Nup58 (nucleoporin 58) - Rat Genome Database

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Gene: Nup58 (nucleoporin 58) Rattus norvegicus
Analyze
Symbol: Nup58
Name: nucleoporin 58
RGD ID: 631334
Description: Enables identical protein binding activity and nuclear localization sequence binding activity. A structural constituent of nuclear pore. Involved in nucleocytoplasmic transport and regulation of protein import into nucleus. Located in nuclear envelope. Part of nuclear pore. Orthologous to human NUP58 (nucleoporin 58); PARTICIPATES IN mRNA nuclear export pathway; RNA transport pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,4-dinitrotoluene; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 58 kDa nucleoporin; nucleoporin like 1; nucleoporin p45; nucleoporin p58; nucleoporin p58/p45; nucleoporin-like 1; nucleoporin-like protein 1; Nup45; Nupl1; p58/p45
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Nup58_v2 ; Nup58_v3 ; Nup58_v1 ; Nup58_v4
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81538,534,340 - 38,583,959 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1538,533,614 - 38,583,178 (-)EnsemblGRCr8
mRatBN7.21534,358,170 - 34,407,160 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1534,358,277 - 34,407,060 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1536,229,670 - 36,261,919 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01537,380,301 - 37,412,551 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01535,835,892 - 35,868,141 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01540,496,754 - 40,545,933 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1540,513,342 - 40,545,824 (-)Ensemblrn6Rnor6.0
Rnor_5.01544,308,883 - 44,358,084 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41539,317,826 - 39,350,075 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1534,076,434 - 34,108,683 (-)NCBICelera
RGSC_v3.11539,332,153 - 39,365,788 (-)NCBI
Cytogenetic Map15p12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (EXP)
2-palmitoylglycerol  (ISO)
3-chloropropane-1,2-diol  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
cisplatin  (ISO)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dibenz[a,h]anthracene  (EXP)
dibenzo[a,l]pyrene  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dimethyl sulfoxide  (ISO)
dorsomorphin  (ISO)
endosulfan  (ISO)
fenvalerate  (EXP)
flavonoids  (EXP)
fluoranthene  (EXP)
genistein  (ISO)
GSK-J4  (ISO)
hydrogen peroxide  (ISO)
indometacin  (EXP)
ivermectin  (ISO)
ketamine  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
N(6)-dimethylallyladenine  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
nitrates  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
paracetamol  (ISO)
phenobarbital  (ISO)
pyrogallol  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Gradient of increasing affinity of importin beta for nucleoporins along the pathway of nuclear import. Ben-Efraim I and Gerace L, J Cell Biol. 2001 Jan 22;152(2):411-7.
2. Regulation of mRNA trafficking by nuclear pore complexes. Bonnet A and Palancade B, Genes (Basel). 2014 Sep 2;5(3):767-91. doi: 10.3390/genes5030767.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Structural analysis of the p62 complex, an assembly of O-linked glycoproteins that localizes near the central gated channel of the nuclear pore complex. Guan T, etal., Mol Biol Cell. 1995 Nov;6(11):1591-603.
5. cDNA cloning and analysis of the expression of nucleoporin p45. Hu T and Gerace L, Gene 1998 Oct 23;221(2):245-53.
6. Molecular and functional characterization of the p62 complex, an assembly of nuclear pore complex glycoproteins. Hu T, etal., J Cell Biol 1996 Aug;134(3):589-601.
7. Allosteric Regulation in Gating the Central Channel of the Nuclear Pore Complex. Koh J and Blobel G, Cell. 2015 Jun 4;161(6):1361-73. doi: 10.1016/j.cell.2015.05.013.
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Molecular architecture of the transport channel of the nuclear pore complex. Solmaz SR, etal., Cell. 2011 Oct 28;147(3):590-602. doi: 10.1016/j.cell.2011.09.034.
11. The stoichiometry of the nucleoporin 62 subcomplex of the nuclear pore in solution. Ulrich A, etal., Mol Biol Cell. 2014 May;25(9):1484-92. doi: 10.1091/mbc.E13-12-0745. Epub 2014 Feb 26.
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:17379812   PMID:26025361  


Genomics

Comparative Map Data
Nup58
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81538,534,340 - 38,583,959 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1538,533,614 - 38,583,178 (-)EnsemblGRCr8
mRatBN7.21534,358,170 - 34,407,160 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1534,358,277 - 34,407,060 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1536,229,670 - 36,261,919 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01537,380,301 - 37,412,551 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01535,835,892 - 35,868,141 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01540,496,754 - 40,545,933 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1540,513,342 - 40,545,824 (-)Ensemblrn6Rnor6.0
Rnor_5.01544,308,883 - 44,358,084 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41539,317,826 - 39,350,075 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1534,076,434 - 34,108,683 (-)NCBICelera
RGSC_v3.11539,332,153 - 39,365,788 (-)NCBI
Cytogenetic Map15p12NCBI
NUP58
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381325,301,625 - 25,349,800 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1325,301,524 - 25,365,390 (+)Ensemblhg38GRCh38
GRCh371325,875,763 - 25,923,938 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361324,773,666 - 24,814,561 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341324,773,665 - 24,814,561NCBI
Celera136,939,918 - 6,980,809 (+)NCBICelera
Cytogenetic Map13q12.13NCBI
HuRef136,690,062 - 6,730,691 (+)NCBIHuRef
CHM1_11325,843,885 - 25,884,759 (+)NCBICHM1_1
T2T-CHM13v2.01324,511,318 - 24,559,471 (+)NCBIT2T-CHM13v2.0
Nup58
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391460,442,733 - 60,488,951 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1460,442,731 - 60,488,956 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm39 Ensembl1460,422,061 - 60,488,880 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381460,205,284 - 60,251,479 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1460,205,282 - 60,251,507 (-)Ensemblmm10GRCm38
GRCm38.p6 Ensembl1460,184,612 - 60,251,431 (-)Ensemblmm10GRCm38
MGSCv371460,838,305 - 60,870,215 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361459,173,578 - 59,205,488 (-)NCBIMGSCv36mm8
Celera1458,009,157 - 58,041,065 (-)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1431.62NCBI
Nup58
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554974,762,316 - 4,830,547 (+)Ensembl
ChiLan1.0NW_0049554974,762,316 - 4,830,320 (+)NCBIChiLan1.0ChiLan1.0
NUP58
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21424,896,010 - 24,946,435 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11316,006,071 - 16,056,478 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0136,593,682 - 6,634,397 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11324,944,910 - 24,985,657 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1324,948,081 - 24,992,854 (+)EnsemblpanPan2panpan1.1
NUP58
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12514,106,135 - 14,158,518 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2514,106,187 - 14,158,464 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2514,185,956 - 14,238,412 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02514,236,442 - 14,289,531 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2514,236,494 - 14,289,555 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12514,118,744 - 14,171,646 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02514,120,919 - 14,173,588 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02514,169,367 - 14,222,519 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Nup58
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945116,363,560 - 116,413,033 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936688985,746 - 1,025,407 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936688986,037 - 1,025,351 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NUP58
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl113,225,268 - 3,259,427 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1113,225,185 - 3,266,163 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2112,493,997 - 2,499,480 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NUP58
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.134,695,071 - 4,743,659 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl34,695,137 - 4,737,195 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605739,706,724 - 39,748,086 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nup58
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477613,149,019 - 13,219,370 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462477613,149,918 - 13,219,571 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Nup58
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11264,163,186 - 64,211,742 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Nup58
159 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:1543
Count of miRNA genes:360
Interacting mature miRNAs:512
Transcripts:ENSRNOT00000017204, ENSRNOT00000063943
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15231575947315759Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15139411584Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15144836456Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)153185580392671517Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152852773273527732Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152272835342072050Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)152233635152597086Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15278592347785923Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152233635167336351Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat

Markers in Region
RH131539  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21534,379,545 - 34,379,727 (+)MAPPERmRatBN7.2
Rnor_6.01540,518,132 - 40,518,313NCBIRnor6.0
Rnor_5.01544,330,244 - 44,330,425UniSTSRnor5.0
RGSC_v3.41539,322,620 - 39,322,801UniSTSRGSC3.4
Celera1534,081,228 - 34,081,409UniSTS
RH 3.4 Map15229.1UniSTS
Cytogenetic Map15p12UniSTS
RH144130  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21534,373,420 - 34,373,657 (+)MAPPERmRatBN7.2
Rnor_6.01540,512,007 - 40,512,243NCBIRnor6.0
Rnor_5.01544,324,119 - 44,324,355UniSTSRnor5.0
RGSC_v3.41539,316,495 - 39,316,731UniSTSRGSC3.4
Celera1534,075,103 - 34,075,339UniSTS
RH 3.4 Map15220.4UniSTS
Cytogenetic Map15p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000017204   ⟹   ENSRNOP00000017204
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1538,533,614 - 38,583,178 (-)Ensembl
mRatBN7.2 Ensembl1534,358,277 - 34,407,060 (-)Ensembl
Rnor_6.0 Ensembl1540,513,342 - 40,545,824 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000063943   ⟹   ENSRNOP00000063452
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1538,552,942 - 38,583,102 (-)Ensembl
mRatBN7.2 Ensembl1534,376,778 - 34,406,940 (-)Ensembl
Rnor_6.0 Ensembl1540,518,043 - 40,542,495 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095956   ⟹   ENSRNOP00000084647
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1538,549,544 - 38,583,178 (-)Ensembl
mRatBN7.2 Ensembl1534,373,383 - 34,407,060 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101273   ⟹   ENSRNOP00000078538
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1538,549,544 - 38,583,178 (-)Ensembl
mRatBN7.2 Ensembl1534,373,383 - 34,407,060 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000132958   ⟹   ENSRNOP00000110527
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1538,555,621 - 38,573,727 (-)Ensembl
RefSeq Acc Id: NM_139091   ⟹   NP_620791
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81538,550,916 - 38,583,165 (-)NCBI
mRatBN7.21534,374,752 - 34,407,003 (-)NCBI
Rnor_6.01540,513,338 - 40,545,824 (-)NCBI
Rnor_5.01544,308,883 - 44,358,084 (-)NCBI
RGSC_v3.41539,317,826 - 39,350,075 (-)RGD
Celera1534,076,434 - 34,108,683 (-)RGD
Sequence:
RefSeq Acc Id: XM_006252093   ⟹   XP_006252155
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81538,534,340 - 38,583,959 (-)NCBI
mRatBN7.21534,358,170 - 34,407,158 (-)NCBI
Rnor_6.01540,496,754 - 40,545,933 (-)NCBI
Rnor_5.01544,308,883 - 44,358,084 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039092981   ⟹   XP_038948909
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81538,549,542 - 38,583,333 (-)NCBI
mRatBN7.21534,373,378 - 34,407,158 (-)NCBI
RefSeq Acc Id: XM_039092982   ⟹   XP_038948910
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81538,534,340 - 38,583,959 (-)NCBI
mRatBN7.21534,358,170 - 34,407,160 (-)NCBI
RefSeq Acc Id: NP_620791   ⟸   NM_139091
- UniProtKB: Q9QWK7 (UniProtKB/Swiss-Prot),   Q9JHE1 (UniProtKB/Swiss-Prot),   Q9Z2W7 (UniProtKB/Swiss-Prot),   P70581 (UniProtKB/Swiss-Prot),   A6K695 (UniProtKB/TrEMBL),   A0A8I6G353 (UniProtKB/TrEMBL),   A6K694 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252155   ⟸   XM_006252093
- Peptide Label: isoform X2
- UniProtKB: A0A8L2Q9I5 (UniProtKB/TrEMBL),   A6K693 (UniProtKB/TrEMBL),   A6K694 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000063452   ⟸   ENSRNOT00000063943
Ensembl Acc Id: ENSRNOP00000017204   ⟸   ENSRNOT00000017204
RefSeq Acc Id: XP_038948910   ⟸   XM_039092982
- Peptide Label: isoform X3
- UniProtKB: A6K694 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038948909   ⟸   XM_039092981
- Peptide Label: isoform X1
- UniProtKB: A6K694 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000078538   ⟸   ENSRNOT00000101273
Ensembl Acc Id: ENSRNOP00000084647   ⟸   ENSRNOT00000095956
Ensembl Acc Id: ENSRNOP00000110527   ⟸   ENSRNOT00000132958

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P70581-F1-model_v2 AlphaFold P70581 1-585 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699734
Promoter ID:EPDNEW_R10257
Type:multiple initiation site
Name:Nup58_1
Description:nucleoporin 58
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01540,545,858 - 40,545,918EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:631334 AgrOrtholog
BioCyc Gene G2FUF-13535 BioCyc
Ensembl Genes ENSRNOG00000012644 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000017204 ENTREZGENE
  ENSRNOT00000063943.3 UniProtKB/Swiss-Prot
  ENSRNOT00000095956 ENTREZGENE
  ENSRNOT00000095956.1 UniProtKB/Swiss-Prot
  ENSRNOT00000101273 ENTREZGENE
Gene3D-CATH 6.10.140.1350 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7190650 IMAGE-MGC_LOAD
InterPro Nucleoporin_p58/p45 UniProtKB/Swiss-Prot
KEGG Report rno:245922 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93109 IMAGE-MGC_LOAD
NCBI Gene 245922 ENTREZGENE
PANTHER NUCLEOPORIN P58/P45 UniProtKB/Swiss-Prot
  PTHR13437 UniProtKB/Swiss-Prot
Pfam Nucleoporin_FG2 UniProtKB/Swiss-Prot
PhenoGen Nup58 PhenoGen
RatGTEx ENSRNOG00000012644 RatGTEx
UniProt A0A8I6G353 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2Q9I5 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0M523_RAT UniProtKB/TrEMBL
  A6K693 ENTREZGENE, UniProtKB/TrEMBL
  A6K694 ENTREZGENE, UniProtKB/TrEMBL
  A6K695 ENTREZGENE, UniProtKB/TrEMBL
  D3ZVG3_RAT UniProtKB/TrEMBL
  NUP58_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q9JHE1 ENTREZGENE
  Q9QWK7 ENTREZGENE
  Q9Z2W7 ENTREZGENE
UniProt Secondary Q9JHE1 UniProtKB/Swiss-Prot
  Q9QWK7 UniProtKB/Swiss-Prot
  Q9Z2W7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-19 Nup58  nucleoporin 58  Nupl1  nucleoporin like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Nupl1  nucleoporin like 1  p58/p45  nucleoporin p58  Symbol and Name updated 1299863 APPROVED