Tnfrsf12a (TNF receptor superfamily member 12A) - Rat Genome Database

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Gene: Tnfrsf12a (TNF receptor superfamily member 12A) Rattus norvegicus
Analyze
Symbol: Tnfrsf12a
Name: TNF receptor superfamily member 12A
RGD ID: 631329
Description: Involved in positive regulation of collagen biosynthetic process. Predicted to be located in cell surface and ruffle. Predicted to be active in plasma membrane. Orthologous to human TNFRSF12A (TNF receptor superfamily member 12A); PARTICIPATES IN cytokine mediated signaling pathway; INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Fn14; MGC72653; tumor necrosis factor receptor superfamily member 12A; tumor necrosis factor receptor superfamily, member 12a
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81013,211,670 - 13,213,666 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1013,211,673 - 13,213,704 (-)EnsemblGRCr8
mRatBN7.21012,707,077 - 12,709,071 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1012,689,890 - 12,709,045 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1017,450,479 - 17,452,451 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01016,939,272 - 16,941,244 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01012,439,729 - 12,441,702 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01012,995,904 - 12,997,930 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1012,995,904 - 12,997,930 (-)Ensemblrn6Rnor6.0
Rnor_5.01012,818,949 - 12,820,975 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41012,940,334 - 12,942,343 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1012,402,383 - 12,404,393 (-)NCBICelera
RGSC_v3.11012,940,333 - 12,942,343 (-)NCBI
Cytogenetic Map10q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-citrinin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-butoxyethanol  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-bromo-2'-deoxyuridine  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acetamide  (EXP)
acrolein  (EXP)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
antimycin A  (ISO)
arachidonic acid  (ISO)
aripiprazole  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
azathioprine  (ISO)
Azoxymethane  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
cefaloridine  (EXP)
chloropicrin  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
ciglitazone  (EXP)
cisplatin  (ISO)
clofibric acid  (EXP)
cobalt dichloride  (EXP,ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
corosolic acid  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
curcumin  (EXP)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dichloroacetic acid  (ISO)
dimethyl sulfoxide  (EXP)
dioxygen  (EXP,ISO)
diquat  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
elemental selenium  (ISO)
Enterolactone  (ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
etoposide  (ISO)
fenamidone  (ISO)
fipronil  (EXP)
fluoranthene  (ISO)
folic acid  (ISO)
formaldehyde  (EXP,ISO)
furan  (EXP,ISO)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
GW 7647  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
indole-3-methanol  (EXP)
indometacin  (ISO)
irinotecan  (EXP)
iron dichloride  (ISO)
isoprenaline  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
leflunomide  (ISO)
Licochalcone B  (ISO)
lidocaine  (EXP)
lipopolysaccharide  (EXP)
manganese(II) chloride  (ISO)
mechlorethamine  (ISO)
melamine  (EXP)
menadione  (ISO)
mercury dichloride  (EXP)
metacetamol  (ISO)
methamphetamine  (EXP)
methapyrilene  (EXP)
methimazole  (EXP)
methotrexate  (ISO)
methylmercury chloride  (ISO)
methylmercury(1+)  (EXP)
microcystin-LR  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-methyl-N-nitrosourea  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (EXP)
naphthalene  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
ochratoxin A  (ISO)
ofloxacin  (EXP)
okadaic acid  (ISO)
orphenadrine  (EXP)
oxaliplatin  (EXP)
ozone  (EXP,ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
pentanal  (ISO)
pentane-2,3-dione  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (EXP,ISO)
phenylephrine  (EXP)
phenylmercury acetate  (ISO)
phosgene  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
propiconazole  (EXP)
quercetin  (ISO)
rac-lactic acid  (ISO)
ranitidine  (EXP)
rotenone  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sodium fluoride  (ISO)
Soman  (EXP)
succimer  (ISO)
sulfadimethoxine  (EXP)
sulforaphane  (EXP)
sunitinib  (ISO)
T-2 toxin  (EXP,ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
toluene 2,4-diisocyanate  (ISO)
topotecan  (EXP)
torcetrapib  (ISO)
triacsin C  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cell surface  (ISO)
membrane  (IEA)
plasma membrane  (IBA,IEA,ISO)
ruffle  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Pro-inflammatory effect of TWEAK/Fn14 interaction on human umbilical vein endothelial cells. Harada N, etal., Biochem Biophys Res Commun 2002 Dec 6;299(3):488-93.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Deletion of Fn14 receptor protects from right heart fibrosis and dysfunction. Novoyatleva T, etal., Basic Res Cardiol. 2013 Mar;108(2):325. doi: 10.1007/s00395-012-0325-x. Epub 2013 Jan 17.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10551889   PMID:11728344   PMID:12477932   PMID:12821115   PMID:14573547   PMID:16762976   PMID:19629561   PMID:20082609   PMID:21525013   PMID:22555979   PMID:23873135   PMID:24571920  
PMID:29249219   PMID:31610210   PMID:34047412  


Genomics

Comparative Map Data
Tnfrsf12a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81013,211,670 - 13,213,666 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1013,211,673 - 13,213,704 (-)EnsemblGRCr8
mRatBN7.21012,707,077 - 12,709,071 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1012,689,890 - 12,709,045 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1017,450,479 - 17,452,451 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01016,939,272 - 16,941,244 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01012,439,729 - 12,441,702 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01012,995,904 - 12,997,930 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1012,995,904 - 12,997,930 (-)Ensemblrn6Rnor6.0
Rnor_5.01012,818,949 - 12,820,975 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41012,940,334 - 12,942,343 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1012,402,383 - 12,404,393 (-)NCBICelera
RGSC_v3.11012,940,333 - 12,942,343 (-)NCBI
Cytogenetic Map10q12NCBI
TNFRSF12A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38163,020,368 - 3,022,383 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl163,018,445 - 3,022,385 (+)Ensemblhg38GRCh38
GRCh37163,070,369 - 3,072,384 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36163,010,361 - 3,012,385 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34163,010,360 - 3,012,382NCBI
Celera163,275,870 - 3,277,940 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef163,042,784 - 3,043,958 (+)NCBIHuRef
CHM1_1163,070,187 - 3,072,258 (+)NCBICHM1_1
T2T-CHM13v2.0163,046,940 - 3,048,955 (+)NCBIT2T-CHM13v2.0
Tnfrsf12a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391723,894,419 - 23,896,423 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1723,894,419 - 23,896,442 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381723,675,445 - 23,677,449 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1723,675,445 - 23,677,468 (-)Ensemblmm10GRCm38
MGSCv371723,812,412 - 23,814,416 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361723,403,067 - 23,405,066 (-)NCBIMGSCv36mm8
Celera1724,181,651 - 24,183,653 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1711.99NCBI
Tnfrsf12a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544214,320,159 - 14,322,146 (-)Ensembl
ChiLan1.0NW_00495544214,320,159 - 14,322,146 (-)NCBIChiLan1.0ChiLan1.0
TNFRSF12A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2183,565,122 - 3,567,175 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1167,343,507 - 7,345,554 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,962,179 - 1,964,223 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1163,134,577 - 3,136,581 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl163,134,577 - 3,136,581 (+)EnsemblpanPan2panpan1.1
TNFRSF12A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,166,160 - 38,168,189 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl638,166,160 - 38,168,189 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha639,406,703 - 39,408,732 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0638,476,762 - 38,478,791 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl638,476,762 - 38,478,906 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1638,162,557 - 38,164,586 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,135,059 - 38,137,088 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0638,610,821 - 38,612,857 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tnfrsf12a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344105,558,357 - 105,560,277 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366941,149,076 - 1,151,151 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366941,149,169 - 1,151,098 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNFRSF12A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl339,166,298 - 39,168,302 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1339,166,288 - 39,168,294 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2340,531,414 - 40,533,682 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TNFRSF12A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.152,763,633 - 2,765,692 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl52,763,714 - 2,765,137 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606828,066,705 - 28,068,765 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tnfrsf12a
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v19982,427 - 984,442 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tnfrsf12a
14 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:365
Count of miRNA genes:201
Interacting mature miRNAs:221
Transcripts:ENSRNOT00000004842
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10666111835509383Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135730538Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10130004247Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1092219745922197Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)10210370847103708Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10117749933Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138832698Rat

Markers in Region
RH129279  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21012,707,219 - 12,707,410 (+)MAPPERmRatBN7.2
Rnor_6.01012,996,042 - 12,996,232NCBIRnor6.0
Rnor_5.01012,819,087 - 12,819,277UniSTSRnor5.0
RGSC_v3.41012,940,472 - 12,940,662UniSTSRGSC3.4
Celera1012,402,521 - 12,402,711UniSTS
Cytogenetic Map10q12UniSTS
BI281199  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21012,706,630 - 12,706,795 (+)MAPPERmRatBN7.2
Rnor_6.01012,995,453 - 12,995,617NCBIRnor6.0
Rnor_5.01012,818,498 - 12,818,662UniSTSRnor5.0
RGSC_v3.41012,939,883 - 12,940,047UniSTSRGSC3.4
Celera1012,401,932 - 12,402,096UniSTS
Cytogenetic Map10q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 160 91 90 59 88 59 6 352 188 11 139 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000004842   ⟹   ENSRNOP00000004843
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1013,211,675 - 13,213,652 (-)Ensembl
mRatBN7.2 Ensembl1012,707,077 - 12,709,045 (-)Ensembl
Rnor_6.0 Ensembl1012,995,904 - 12,997,930 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107526   ⟹   ENSRNOP00000080282
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1013,211,673 - 13,213,704 (-)Ensembl
mRatBN7.2 Ensembl1012,689,890 - 12,709,026 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116910   ⟹   ENSRNOP00000097829
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1013,211,673 - 13,213,619 (-)Ensembl
mRatBN7.2 Ensembl1012,689,890 - 12,709,026 (-)Ensembl
RefSeq Acc Id: NM_181086   ⟹   NP_851600
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81013,211,675 - 13,213,648 (-)NCBI
mRatBN7.21012,707,082 - 12,709,055 (-)NCBI
Rnor_6.01012,995,904 - 12,997,930 (-)NCBI
Rnor_5.01012,818,949 - 12,820,975 (-)NCBI
RGSC_v3.41012,940,334 - 12,942,343 (-)RGD
Celera1012,402,383 - 12,404,393 (-)RGD
Sequence:
RefSeq Acc Id: XM_039085851   ⟹   XP_038941779
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81013,211,670 - 13,213,666 (-)NCBI
mRatBN7.21012,707,077 - 12,709,071 (-)NCBI
RefSeq Acc Id: NP_851600   ⟸   NM_181086
- Peptide Label: precursor
- UniProtKB: Q80XX9 (UniProtKB/TrEMBL),   A6HCK9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000004843   ⟸   ENSRNOT00000004842
RefSeq Acc Id: XP_038941779   ⟸   XM_039085851
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000080282   ⟸   ENSRNOT00000107526
Ensembl Acc Id: ENSRNOP00000097829   ⟸   ENSRNOT00000116910

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V6F9-F1-model_v2 AlphaFold G3V6F9 1-129 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696993
Promoter ID:EPDNEW_R7517
Type:initiation region
Name:Tnfrsf12a_1
Description:TNF receptor superfamily member 12A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01012,997,930 - 12,997,990EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:631329 AgrOrtholog
BioCyc Gene G2FUF-25915 BioCyc
Ensembl Genes ENSRNOG00000003546 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000004842 ENTREZGENE
  ENSRNOT00000004842.7 UniProtKB/TrEMBL
  ENSRNOT00000107526.2 UniProtKB/TrEMBL
  ENSRNOT00000116910.2 UniProtKB/TrEMBL
Gene3D-CATH 4.10.400.20 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6887545 IMAGE-MGC_LOAD
InterPro TNFR_12 UniProtKB/TrEMBL
KEGG Report rno:302965 UniProtKB/TrEMBL
MGC_CLONE MGC:72653 IMAGE-MGC_LOAD
NCBI Gene 302965 ENTREZGENE
PANTHER PTHR32037 UniProtKB/TrEMBL
  TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 12A UniProtKB/TrEMBL
Pfam stn_TNFRSF12A UniProtKB/TrEMBL
PhenoGen Tnfrsf12a PhenoGen
PRINTS TNFACTORR12 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000003546 RatGTEx
UniProt A0A8I5ZQC8_RAT UniProtKB/TrEMBL
  A0A8I6AVJ2_RAT UniProtKB/TrEMBL
  A6HCK9 ENTREZGENE, UniProtKB/TrEMBL
  A6HCL0_RAT UniProtKB/TrEMBL
  G3V6F9_RAT UniProtKB/TrEMBL
  Q80XX9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-07-05 Tnfrsf12a  TNF receptor superfamily member 12A  Tnfrsf12a  tumor necrosis factor receptor superfamily, member 12a  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-02-11 Tnfrsf12a  tumor necrosis factor receptor superfamily, member 12a      Symbol and Name status set to approved 625702 APPROVED