Gene:	Fzd9 ( Rattus norvegicus ) frizzled homolog 9 (Drosophila)
Description:	relocalizes axin from the cytoplasm to the plasma membrane
ArrayIDs:	A_44_P367465; 6146125; 6686782; GE1277836; 6080762; 6645020; 5849481;  (details...)
Gene Type:	protein-coding
Additional Data
Homologs
Homo sapiens: FZD9     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Fzd9     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Fzd9 Rat Celera Assembly 12 23189657 - 23191971     RGSC genome assembly v3.4 12 22581510 - 22583824     Cytogenetic 12 q12     genome assembly 3.1 12 22572254 - 22574569 Mus musculus Fzd9 Mouse genome assembly build 36.1 5 135724807 - 135726917     Cytogenetic 5 5 G2 Homo sapiens FZD9 human genome assembly 7 72292963 - 72295149     Human genome assembly build 36.2 7 72486045 - 72488386     Cytogenetic 7 q11.23   View comparative maps:      NCBI MapViewer
Genome
View:
Browsers:	Select a browser to viewGene (GBrowse)Gene and SNPs (GBrowse)UCSCVCMAPEnsemblNCBIECRVISTAVISTA+UCSC
Annotation
Molecular Function	Note Reference functions as a Wnt/beta-catenin signaling receptor 632661 Gene Ontology non-G-protein coupled 7TM receptor activity,  G-protein coupled receptor activity,  Wnt receptor activity (details...)
Biological Process	Gene Ontology multicellular organismal development,  G-protein coupled receptor protein signaling pathway,  neuroblast proliferation ...  (details...)
Cellular Component	Gene Ontology perinuclear region of cytoplasm,  integral to membrane,  plasma membrane ...  (details...)
Pathway	Ontology Wnt signaling pathway,  the planar cell polarity Wnt signaling pathway (details...)
Mutation/over- and underexpression	Note Reference in mouse overexpression induces hyperphosphorylation and relocalization of cytosolic beta-catenin 632661
External Links
Databases	DATABASE ID SOURCE SMART: FRI IPI PROSITE: G_PROTEIN_RECEP_F2_4 IPI PROSITE: FZ IPI UNIPARC: UPI00000E726B IPI KEGG Report: rno:266608 ENTREZGENE HomoloGene Group ID: 2619 ENTREZGENE Germonline: 628817 Pfam: Fz IPI Pfam: Frizzled IPI KEGG Pathway: 05217 ENTREZGENE KEGG Pathway: 05210 ENTREZGENE KEGG Pathway: 04916 ENTREZGENE KEGG Pathway: 05200 ENTREZGENE KEGG Pathway: 04310 ENTREZGENE InterPro: Frizzled_Cys-rich. IPI InterPro: Frizzled. IPI InterPro: GPCR_2-like. IPI InterPro: Frizzled_related. IPI InterPro: Frizzled_dom_subgr. IPI InterPro: Frizzled-like_dom. IPI IPI: IPI00203116 IPI Ensembl Protein: ENSRNOP00000001973 IPI Gene3D-CATH: Frizzled_Cys-rich IPI Entrez Gene: Fzd9 ENTREZGENE UniProt: Q8K4C8_RAT IPI Ensembl Genes: ENSRNOG00000001452 IPI Superfamily-SCOP: Frizzled_Cys-rich IPI PANTHER: Fz_related IPI PRINTS: FRIZZLED. IPI
Sequences	Nucleotide: AC090529 Get FASTA Search GEO Profiles Nucleotide: CH473973 Get FASTA Search GEO Profiles Nucleotide: NM_153305 Get FASTA Search GEO Profiles Nucleotide: AF455054 Get FASTA Search GEO Profiles Nucleotide: DQ211688 Get FASTA Search GEO Profiles Nucleotide: DQ211689 Get FASTA Search GEO Profiles (View all 6 Nucleotide Accessions) Protein: NP_695217 Get FASTA Protein: EDM13380 Get FASTA Protein: AAN03014 Get FASTA Protein: ABB20593 Get FASTA Protein: ABB20594 Get FASTA Protein: Q8K4C8 Get FASTA (View all 6 Protein Accessions)
Clusters	UniGene: 96335
References
Curated References	6 references in RGD related to Fzd9
Other References	1 other references at PubMed related to Fzd9
Database Information
RGD ID	628817
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 10-SEP-04: Fzd9 frizzled homolog 9 (Drosophila) APPROVED Symbol and Name status set to approved 1299863 27-FEB-03: Fzd9 frizzled homolog 9 (Drosophila) PROVISIONAL Symbol and Name status set to provisional 70820