Vps4a (vacuolar protein sorting 4 homolog A) - Rat Genome Database

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Gene: Vps4a (vacuolar protein sorting 4 homolog A) Rattus norvegicus
Analyze
Symbol: Vps4a
Name: vacuolar protein sorting 4 homolog A
RGD ID: 628810
Description: Enables small GTPase binding activity. Predicted to be involved in several processes, including negative regulation of cell cycle process; proteolysis involved in protein catabolic process; and vesicle organization. Predicted to act upstream of or within endosome organization. Located in early endosome. Orthologous to human VPS4A (vacuolar protein sorting 4 homolog A); PARTICIPATES IN autophagy pathway; endocytosis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: vacuolar protein sorting 4 homolog A (S. cerevisiae); vacuolar protein sorting 4a; vacuolar protein sorting 4a (yeast); vacuolar protein sorting protein 4a; vacuolar protein sorting-associated protein 4A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81951,838,411 - 51,858,639 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1951,833,914 - 51,872,423 (+)EnsemblGRCr8
mRatBN7.21934,934,999 - 34,948,888 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1934,934,961 - 34,948,887 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1941,750,699 - 41,763,746 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01942,404,046 - 42,417,093 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01944,703,279 - 44,716,379 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01939,230,050 - 39,243,298 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1939,229,754 - 39,243,496 (+)Ensemblrn6Rnor6.0
Rnor_5.01950,093,663 - 50,106,670 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41936,887,345 - 36,900,864 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1934,358,772 - 34,371,812 (+)NCBICelera
RGSC_v3.11936,892,225 - 36,905,745 (+)NCBI
Cytogenetic Map19q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
centrosome  (IEA,ISO)
cytoplasm  (IBA,IEA,ISO)
cytosol  (IEA,ISO)
early endosome  (IDA,IEA,ISO)
endosome  (IBA,IEA,ISO)
endosome membrane  (IEA,ISO)
Flemming body  (IEA,ISO)
late endosome  (IEA,ISO)
late endosome membrane  (IEA)
lysosome  (IEA,ISO)
midbody  (IEA,ISO,ISS)
nucleus  (IEA,ISO)
perinuclear region of cytoplasm  (IEA,ISO)
plasma membrane  (IEA,ISO)
spindle  (IEA)
spindle pole  (IEA,ISO)
vacuolar membrane  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Information Derived from GenBank Report RGD, Sept. 2003
7. How do ESCRT proteins control autophagy? Rusten TE and Stenmark H, J Cell Sci. 2009 Jul 1;122(Pt 13):2179-83.
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
9. Vps4-A (vacuolar protein sorting 4-A) is a binding partner for a novel Rho family GTPase, Rnd2. Tanaka H, etal., Biochem J. 2002 Jul 15;365(Pt 2):349-53.
Additional References at PubMed
PMID:10637304   PMID:11559748   PMID:11563910   PMID:11595185   PMID:12594041   PMID:15075231   PMID:16193069   PMID:16973552   PMID:17853893   PMID:17928862   PMID:17940959   PMID:18005716  
PMID:18606141   PMID:19129479   PMID:19199708   PMID:20616062   PMID:21238931   PMID:22547407   PMID:22660413   PMID:23533145   PMID:24107264   PMID:24814515   PMID:24878737   PMID:28064406  
PMID:29476059  


Genomics

Comparative Map Data
Vps4a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81951,838,411 - 51,858,639 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1951,833,914 - 51,872,423 (+)EnsemblGRCr8
mRatBN7.21934,934,999 - 34,948,888 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1934,934,961 - 34,948,887 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1941,750,699 - 41,763,746 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01942,404,046 - 42,417,093 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01944,703,279 - 44,716,379 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01939,230,050 - 39,243,298 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1939,229,754 - 39,243,496 (+)Ensemblrn6Rnor6.0
Rnor_5.01950,093,663 - 50,106,670 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41936,887,345 - 36,900,864 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1934,358,772 - 34,371,812 (+)NCBICelera
RGSC_v3.11936,892,225 - 36,905,745 (+)NCBI
Cytogenetic Map19q12NCBI
VPS4A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381669,311,350 - 69,326,939 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1669,311,336 - 69,326,939 (+)Ensemblhg38GRCh38
GRCh371669,345,253 - 69,360,842 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361667,902,788 - 67,916,447 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341667,902,787 - 67,916,446NCBI
Celera1653,859,828 - 53,873,486 (+)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1655,223,517 - 55,237,174 (+)NCBIHuRef
CHM1_11670,753,291 - 70,766,948 (+)NCBICHM1_1
T2T-CHM13v2.01675,113,104 - 75,128,634 (+)NCBIT2T-CHM13v2.0
Vps4a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398107,757,901 - 107,772,392 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8107,757,854 - 107,772,387 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm388107,031,269 - 107,045,760 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8107,031,222 - 107,045,755 (+)Ensemblmm10GRCm38
MGSCv378109,555,226 - 109,569,656 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv368109,920,455 - 109,934,885 (+)NCBIMGSCv36mm8
Celera8111,257,885 - 111,272,306 (+)NCBICelera
Cytogenetic Map8D3NCBI
cM Map853.53NCBI
Vps4a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554847,368,938 - 7,375,969 (-)Ensembl
ChiLan1.0NW_0049554847,368,938 - 7,375,964 (-)NCBIChiLan1.0ChiLan1.0
VPS4A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21878,845,740 - 78,869,672 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11684,767,388 - 84,781,302 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01649,685,827 - 49,699,542 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11668,946,466 - 69,085,714 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1669,074,091 - 69,085,714 (+)EnsemblpanPan2panpan1.1
VPS4A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1580,327,059 - 80,340,380 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha580,311,739 - 80,330,670 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0580,755,360 - 80,774,301 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl580,759,718 - 80,774,322 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1580,582,504 - 80,601,442 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0580,265,344 - 80,284,280 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0580,904,921 - 80,923,853 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Vps4a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934940,144,891 - 40,156,804 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647519,432,229 - 19,444,223 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647519,432,311 - 19,444,223 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VPS4A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl617,654,638 - 17,669,841 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1617,657,792 - 17,669,560 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2616,604,522 - 16,616,293 (-)NCBISscrofa10.2Sscrofa10.2susScr3
VPS4A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1558,081,800 - 58,095,115 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl558,082,521 - 58,095,173 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604720,811,652 - 20,825,117 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vps4a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474617,047,519 - 17,054,738 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474617,044,173 - 17,059,295 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Vps4a
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11726,756,167 - 26,770,097 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Vps4a
93 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:114
Count of miRNA genes:91
Interacting mature miRNAs:99
Transcripts:ENSRNOT00000027607, ENSRNOT00000050612
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19799775052997750Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)191922068964220689Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19799775052997750Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)194622677874246245Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194438513474246245Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19799775052997750Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19799775052997750Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
1354607Gmadr1Adrenal mass QTL 15.83adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)194072709254856850Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)192010930665109306Rat
1354600Salc2Saline consumption QTL 29.910.001drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)194072709254856850Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)194172254674246245Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat
1354633Bw28Body weight QTL 286.04body mass (VT:0001259)body weight (CMO:0000012)194072709254856850Rat

Markers in Region
AW553189  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21934,948,535 - 34,948,650 (+)MAPPERmRatBN7.2
Rnor_6.01939,243,567 - 39,243,681NCBIRnor6.0
Rnor_5.01950,106,939 - 50,107,053UniSTSRnor5.0
RGSC_v3.41936,901,133 - 36,901,247UniSTSRGSC3.4
Celera1934,372,081 - 34,372,195UniSTS
Cytogenetic Map19q12UniSTS
AI325971  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21934,948,630 - 34,948,806 (+)MAPPERmRatBN7.2
Rnor_6.01939,243,662 - 39,243,837NCBIRnor6.0
Rnor_5.01950,107,034 - 50,107,209UniSTSRnor5.0
RGSC_v3.41936,901,228 - 36,901,403UniSTSRGSC3.4
Celera1934,372,176 - 34,372,351UniSTS
Cytogenetic Map19q12UniSTS
RH129713  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21934,948,652 - 34,948,834 (+)MAPPERmRatBN7.2
Rnor_6.01939,243,684 - 39,243,865NCBIRnor6.0
Rnor_5.01950,107,056 - 50,107,237UniSTSRnor5.0
RGSC_v3.41936,901,250 - 36,901,431UniSTSRGSC3.4
Celera1934,372,198 - 34,372,379UniSTS
RH 3.4 Map19315.1UniSTS
Cytogenetic Map19q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000050612   ⟹   ENSRNOP00000046690
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1951,833,914 - 51,858,637 (+)Ensembl
mRatBN7.2 Ensembl1934,934,961 - 34,948,887 (+)Ensembl
Rnor_6.0 Ensembl1939,229,754 - 39,243,496 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000146477   ⟹   ENSRNOP00000100072
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1951,833,914 - 51,872,423 (+)Ensembl
RefSeq Acc Id: NM_145678   ⟹   NP_663711
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81951,844,793 - 51,858,639 (+)NCBI
mRatBN7.21934,935,040 - 34,948,888 (+)NCBI
Rnor_6.01939,230,243 - 39,243,298 (+)NCBI
Rnor_5.01950,093,663 - 50,106,670 (+)NCBI
RGSC_v3.41936,887,345 - 36,900,864 (+)RGD
Celera1934,358,772 - 34,371,812 (+)RGD
Sequence:
RefSeq Acc Id: XM_006255560   ⟹   XP_006255622
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81951,844,726 - 51,857,897 (+)NCBI
mRatBN7.21934,934,999 - 34,947,824 (+)NCBI
Rnor_6.01939,230,050 - 39,242,855 (+)NCBI
Rnor_5.01950,093,663 - 50,106,670 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063277786   ⟹   XP_063133856
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81951,838,413 - 51,858,639 (+)NCBI
RefSeq Acc Id: XM_063277787   ⟹   XP_063133857
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81951,838,411 - 51,858,639 (+)NCBI
RefSeq Acc Id: NP_663711   ⟸   NM_145678
- UniProtKB: Q793F9 (UniProtKB/Swiss-Prot),   A6IYY4 (UniProtKB/TrEMBL),   Q6IRG3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255622   ⟸   XM_006255560
- Peptide Label: isoform X1
- UniProtKB: Q6IRG3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000046690   ⟸   ENSRNOT00000050612
RefSeq Acc Id: XP_063133857   ⟸   XM_063277787
- Peptide Label: isoform X2
- UniProtKB: F7F1Y3 (UniProtKB/TrEMBL),   Q6IRG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133856   ⟸   XM_063277786
- Peptide Label: isoform X2
- UniProtKB: F7F1Y3 (UniProtKB/TrEMBL),   Q6IRG3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000100072   ⟸   ENSRNOT00000146477
Protein Domains
AAA+ ATPase   MIT

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q793F9-F1-model_v2 AlphaFold Q793F9 1-437 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628810 AgrOrtholog
BioCyc Gene G2FUF-5768 BioCyc
Ensembl Genes ENSRNOG00000020351 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000050612 ENTREZGENE
  ENSRNOT00000146477 ENTREZGENE
Gene3D-CATH 1.10.8.60 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot
  Phosphotransferase system, lactose/cellobiose-type IIA subunit UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7096867 IMAGE-MGC_LOAD
InterPro AAA+_ATPase UniProtKB/Swiss-Prot
  AAA_lid_3 UniProtKB/Swiss-Prot
  ATPase_AAA_core UniProtKB/Swiss-Prot
  ATPase_AAA_CS UniProtKB/Swiss-Prot
  MIT UniProtKB/Swiss-Prot
  MIT_dom_sf UniProtKB/Swiss-Prot
  MT-severing_AAA_ATPase UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  Vps4_C UniProtKB/Swiss-Prot
  VPS4_MIT UniProtKB/Swiss-Prot
KEGG Report rno:246772 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91460 IMAGE-MGC_LOAD
NCBI Gene 246772 ENTREZGENE
PANTHER AAA DOMAIN-CONTAINING UniProtKB/Swiss-Prot
  VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4A UniProtKB/Swiss-Prot
Pfam AAA UniProtKB/Swiss-Prot
  AAA_lid_3 UniProtKB/Swiss-Prot
  MIT UniProtKB/Swiss-Prot
  Vps4_C UniProtKB/Swiss-Prot
PhenoGen Vps4a PhenoGen
PROSITE AAA UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000020351 RatGTEx
SMART AAA UniProtKB/Swiss-Prot
  MIT UniProtKB/Swiss-Prot
Superfamily-SCOP SSF116846 UniProtKB/Swiss-Prot
  SSF52540 UniProtKB/Swiss-Prot
UniProt A0ABK0LGR3_RAT UniProtKB/TrEMBL
  A6IYY4 ENTREZGENE, UniProtKB/TrEMBL
  F7F1Y3 ENTREZGENE, UniProtKB/TrEMBL
  Q6IRG3 ENTREZGENE, UniProtKB/TrEMBL
  Q793F9 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-13 Vps4a  vacuolar protein sorting 4 homolog A  Vps4a  vacuolar protein sorting 4 homolog A (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-25 Vps4a  vacuolar protein sorting 4 homolog A (S. cerevisiae)  Vps4a  vacuolar protein sorting 4a (yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Vps4a  vacuolar protein sorting 4a (yeast)    vacuolar protein sorting protein 4a  Name updated 1299863 APPROVED
2003-02-27 Vps4a  vacuolar protein sorting protein 4a      Symbol and Name status set to provisional 70820 PROVISIONAL