Ppif (peptidylprolyl isomerase F) - Rat Genome Database

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Gene: Ppif (peptidylprolyl isomerase F) Rattus norvegicus
Analyze
Symbol: Ppif
Name: peptidylprolyl isomerase F
RGD ID: 628670
Description: Enables cyclosporin A binding activity; peptide binding activity; and peptidyl-prolyl cis-trans isomerase activity. Involved in regulation of apoptotic process and regulation of mitochondrial membrane permeability. Located in mitochondrial inner membrane. Is active in mitochondrial matrix. Orthologous to human PPIF (peptidylprolyl isomerase F); PARTICIPATES IN toxoplasmosis pathway; INTERACTS WITH 1,1'-azobis(N,N-dimethylformamide); 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cyclophilin D; cyclophilin F; CyP-D; CypD; MGC93084; Peptidyl-prolyl cis-trans isomerase; peptidyl-prolyl cis-trans isomerase F, mitochondrial; peptidyl-prolyl cis-trans isomerase, mitochondrial; peptidylprolyl isomerase F (cyclophilin F); PPIase; PPIase F; rotamase; rotamase F
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Arunc2 Arunc1
Latest Assembly: GRCr8 - GRCr8 Assembly
NCBI Annotation Information: Note: This gene encodes a 177 aa mature peptide that is found in the mitochondrion. It has been labeled 'cyclophilin D'. This same name has also been applied to a different cytoplasmic protein of 370 aa, which is represented by GeneID 361967, Ppid. [12 Mar 2012]
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8161,264,001 - 1,270,722 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl161,263,541 - 1,316,954 (+)EnsemblGRCr8
mRatBN7.2161,257,197 - 1,263,919 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl161,257,106 - 1,263,913 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx161,263,511 - 1,270,232 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0162,409,364 - 2,416,086 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0161,270,127 - 1,276,849 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0161,979,191 - 1,985,912 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl161,979,191 - 1,985,908 (+)Ensemblrn6Rnor6.0
Rnor_5.0161,955,730 - 1,962,451 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4161,292,835 - 1,299,556 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera161,234,115 - 1,240,836 (+)NCBICelera
RGSC_v3.1161,292,834 - 1,299,555 (+)NCBI
Cytogenetic Map16p16NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)
intestinal disease  (ISO)
Ulcer  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1'-azobis(N,N-dimethylformamide)  (EXP,ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
albendazole  (ISO)
all-trans-retinoic acid  (ISO)
AM-251  (ISO)
amlodipine  (EXP,ISO)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
auranofin  (EXP,ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
celastrol  (ISO)
choline  (ISO)
cilnidipine  (EXP,ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
corosolic acid  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
curcumin  (ISO)
cyclosporin A  (EXP,ISO)
DDE  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
diclofenac  (ISO)
diquat  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
eugenol  (EXP)
flutamide  (EXP)
folic acid  (ISO)
gedunin  (ISO)
genistein  (EXP)
glycidyl methacrylate  (ISO)
hydrogen peroxide  (EXP,ISO)
iohexol  (EXP,ISO)
isoprenaline  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
kainic acid  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
levofloxacin  (EXP)
LY294002  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
melphalan  (ISO)
menadione  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylparaben  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
NADP zwitterion  (EXP)
NADP(+)  (EXP)
nifedipine  (EXP,ISO)
nitrates  (ISO)
nitrofen  (EXP)
ochratoxin A  (ISO)
oleanolic acid  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (EXP,ISO)
quinolinic acid  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
senecionine  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
sulforaphane  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Purification and N-terminal sequencing of peptidyl-prolyl cis-trans-isomerase from rat liver mitochondrial matrix reveals the existence of a distinct mitochondrial cyclophilin. Connern CP and Halestrap AP, Biochem J 1992 Jun 1;284 ( Pt 2):381-5.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Mitochondrion as a novel site of dichloroacetate biotransformation by glutathione transferase zeta 1. Li W, etal., J Pharmacol Exp Ther. 2011 Jan;336(1):87-94. doi: 10.1124/jpet.110.173195. Epub 2010 Sep 30.
4. Cyclophilin-D promotes the mitochondrial permeability transition but has opposite effects on apoptosis and necrosis. Li Y, etal., Biochem J. 2004 Oct 1;383(Pt 1):101-9.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Direct demonstration of a specific interaction between cyclophilin-D and the adenine nucleotide translocase confirms their role in the mitochondrial permeability transition. Woodfield K, etal., Biochem J. 1998 Dec 1;336 ( Pt 2):287-90.
Additional References at PubMed
PMID:12077116   PMID:12477932   PMID:14651853   PMID:15489334   PMID:15800626   PMID:15800627   PMID:16103352   PMID:16551620   PMID:16675492   PMID:16876914   PMID:18350175   PMID:18614015  
PMID:18667415   PMID:18684715   PMID:18951528   PMID:19094991   PMID:19228691   PMID:19299432   PMID:19801635   PMID:19832699   PMID:20364102   PMID:20588055   PMID:20651005   PMID:20676357  
PMID:21281446   PMID:22726440   PMID:23063677   PMID:26387735   PMID:26975474   PMID:27864141  


Genomics

Comparative Map Data
Ppif
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8161,264,001 - 1,270,722 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl161,263,541 - 1,316,954 (+)EnsemblGRCr8
mRatBN7.2161,257,197 - 1,263,919 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl161,257,106 - 1,263,913 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx161,263,511 - 1,270,232 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0162,409,364 - 2,416,086 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0161,270,127 - 1,276,849 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0161,979,191 - 1,985,912 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl161,979,191 - 1,985,908 (+)Ensemblrn6Rnor6.0
Rnor_5.0161,955,730 - 1,962,451 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4161,292,835 - 1,299,556 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera161,234,115 - 1,240,836 (+)NCBICelera
RGSC_v3.1161,292,834 - 1,299,555 (+)NCBI
Cytogenetic Map16p16NCBI
PPIF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381079,347,469 - 79,355,334 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1079,347,466 - 79,355,337 (+)Ensemblhg38GRCh38
GRCh371081,107,225 - 81,115,090 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361080,777,226 - 80,785,096 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341080,777,225 - 80,785,093NCBI
Celera1074,393,355 - 74,401,225 (+)NCBICelera
Cytogenetic Map10q22.3NCBI
HuRef1075,101,849 - 75,109,719 (+)NCBIHuRef
CHM1_11081,390,186 - 81,398,056 (+)NCBICHM1_1
T2T-CHM13v2.01080,216,813 - 80,224,678 (+)NCBIT2T-CHM13v2.0
Ppif
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391425,693,998 - 25,700,892 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1425,694,578 - 25,700,892 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381425,693,574 - 25,700,468 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1425,694,154 - 25,700,468 (+)Ensemblmm10GRCm38
MGSCv371426,513,656 - 26,519,954 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361424,527,354 - 24,533,652 (+)NCBIMGSCv36mm8
Celera1422,018,432 - 22,024,722 (+)NCBICelera
Cytogenetic Map14A3NCBI
cM Map1415.06NCBI
Ppif
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543713,295,663 - 13,302,175 (-)Ensembl
ChiLan1.0NW_00495543713,295,766 - 13,301,918 (-)NCBIChiLan1.0ChiLan1.0
PPIF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2891,486,543 - 91,496,372 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11091,491,867 - 91,501,079 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01075,860,197 - 75,868,098 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11078,521,996 - 78,530,211 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1078,521,642 - 78,530,202 (+)EnsemblpanPan2panpan1.1
PPIF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1429,074,806 - 29,080,487 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha429,197,719 - 29,204,179 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0429,374,690 - 29,381,134 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl429,374,690 - 29,380,211 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1429,245,431 - 29,251,855 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0429,447,801 - 29,454,224 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0429,801,525 - 29,807,938 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ppif
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721351,911,849 - 51,918,430 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936521404,544 - 411,539 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936521404,574 - 411,381 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPIF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1481,667,672 - 81,689,495 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11481,674,671 - 81,681,977 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21488,334,121 - 88,341,247 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PPIF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1952,109,865 - 52,117,703 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl952,109,272 - 52,117,483 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604812,454,125 - 12,466,531 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppif
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475412,336,427 - 12,342,687 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475412,336,474 - 12,342,687 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ppif
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1131,798,959 - 1,805,378 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ppif
76 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:113
Count of miRNA genes:81
Interacting mature miRNAs:97
Transcripts:ENSRNOT00000014382
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)1638712345387123Rat
1549842Bp248Blood pressure QTL 2480.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1638712345387123Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133425095Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139568015Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139568015Rat
631524Bp75Blood pressure QTL 750.05arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)161177108157035Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683908666195506Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683908666195506Rat
12903955Kidm69Kidney mass QTL 690.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)168392304234212Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683908666195506Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126734272Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16126734272Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683908652786090Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683908666195506Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126734272Rat

Markers in Region
RH128271  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2161,263,583 - 1,263,788 (+)MAPPERmRatBN7.2
Rnor_6.0161,985,577 - 1,985,781NCBIRnor6.0
Rnor_5.0161,962,116 - 1,962,320UniSTSRnor5.0
RGSC_v3.4161,299,221 - 1,299,425UniSTSRGSC3.4
Celera161,240,501 - 1,240,705UniSTS
Cytogenetic Map16p16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000014382   ⟹   ENSRNOP00000014382
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl161,257,215 - 1,263,913 (+)Ensembl
Rnor_6.0 Ensembl161,979,191 - 1,985,908 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000106999   ⟹   ENSRNOP00000085863
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl161,263,541 - 1,270,717 (+)Ensembl
mRatBN7.2 Ensembl161,257,106 - 1,263,909 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000134148   ⟹   ENSRNOP00000100547
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl161,263,541 - 1,299,332 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000139138   ⟹   ENSRNOP00000106563
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl161,263,541 - 1,316,954 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000173909   ⟹   ENSRNOP00000105319
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl161,263,541 - 1,299,239 (+)Ensembl
RefSeq Acc Id: NM_172243   ⟹   NP_758443
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8161,264,001 - 1,270,722 (+)NCBI
mRatBN7.2161,257,197 - 1,263,919 (+)NCBI
Rnor_6.0161,979,191 - 1,985,912 (+)NCBI
Rnor_5.0161,955,730 - 1,962,451 (+)NCBI
RGSC_v3.4161,292,835 - 1,299,556 (+)RGD
Celera161,234,115 - 1,240,836 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_758443 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB08453 (Get FASTA)   NCBI Sequence Viewer  
  AAH86977 (Get FASTA)   NCBI Sequence Viewer  
  EDL75095 (Get FASTA)   NCBI Sequence Viewer  
  EDL75096 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000085863
  ENSRNOP00000085863.1
GenBank Protein P29117 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_758443   ⟸   NM_172243
- Peptide Label: precursor
- UniProtKB: P29117 (UniProtKB/Swiss-Prot),   A6KMH2 (UniProtKB/TrEMBL),   A0A8L2Q6S2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000014382   ⟸   ENSRNOT00000014382
Ensembl Acc Id: ENSRNOP00000085863   ⟸   ENSRNOT00000106999
Ensembl Acc Id: ENSRNOP00000106563   ⟸   ENSRNOT00000139138
Ensembl Acc Id: ENSRNOP00000105319   ⟸   ENSRNOT00000173909
Ensembl Acc Id: ENSRNOP00000100547   ⟸   ENSRNOT00000134148
Protein Domains
PPIase cyclophilin-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P29117-F1-model_v2 AlphaFold P29117 1-206 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699891
Promoter ID:EPDNEW_R10415
Type:initiation region
Name:Ppif_1
Description:peptidylprolyl isomerase F
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0161,979,145 - 1,979,205EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628670 AgrOrtholog
BioCyc Gene G2FUF-12271 BioCyc
Ensembl Genes ENSRNOG00000010558 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000106999 ENTREZGENE
  ENSRNOT00000106999.1 UniProtKB/Swiss-Prot
Gene3D-CATH 2.40.100.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7193156 IMAGE-MGC_LOAD
InterPro Cyclophilin-like_dom_sf UniProtKB/Swiss-Prot
  Cyclophilin-type_PPIase_CS UniProtKB/Swiss-Prot
  Cyclophilin-type_PPIase_dom UniProtKB/Swiss-Prot
KEGG Report rno:282819 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93084 IMAGE-MGC_LOAD
NCBI Gene 282819 ENTREZGENE
PANTHER PEPTIDYL-PROLYL CIS-TRANS ISOMERASE UniProtKB/Swiss-Prot
  PEPTIDYL-PROLYL CIS-TRANS ISOMERASE F, MITOCHONDRIAL UniProtKB/Swiss-Prot
Pfam Pro_isomerase UniProtKB/Swiss-Prot
PhenoGen Ppif PhenoGen
PRINTS CSAPPISMRASE UniProtKB/Swiss-Prot
PROSITE CSA_PPIASE_1 UniProtKB/Swiss-Prot
  CSA_PPIASE_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000010558 RatGTEx
Superfamily-SCOP SSF50891 UniProtKB/Swiss-Prot
UniProt A0A8L2Q6S2 ENTREZGENE
  A0ABK0L8J1_RAT UniProtKB/TrEMBL
  A0ABK0L8K0_RAT UniProtKB/TrEMBL
  A0ABK0LU85_RAT UniProtKB/TrEMBL
  A6KMH2 ENTREZGENE, UniProtKB/TrEMBL
  A6KMH3_RAT UniProtKB/TrEMBL
  P29117 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-04-23 Ppif  peptidylprolyl isomerase F  Ppif  peptidylprolyl isomerase F (cyclophilin F)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Ppif  peptidylprolyl isomerase F (cyclophilin F)    peptidylprolyl isomerase F  Name updated 1299863 APPROVED
2003-02-27 Ppif  peptidylprolyl isomerase F      Symbol and Name status set to provisional 70820 PROVISIONAL