PPIF (peptidylprolyl isomerase F)

Help | FTP Download | Citing RGD | Contact Us

Keyword

Gene: PPIF (peptidylprolyl isomerase F) Homo sapiens

Symbol:

PPIF

Name:

peptidylprolyl isomerase F

Description:

The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

cyclophilin 3; cyclophilin D; cyclophilin F; Cyp-D; CyP-M; CYP3; CypD; FLJ90798; MGC117207; mitochondrial cyclophilin; OTTHUMP00000019925; OTTHUMP00000019926; peptidyl-prolyl cis-trans isomerase F, mitochondrial; peptidyl-prolyl cis-trans isomerase, mitochondral; peptidyl-prolyl cis-trans isomerase, mitochondrial; PPIase F; rotamase F

Orthologs:

Mus musculus : Ppif (peptidylprolyl isomerase F (cyclophilin F)) MGI
Rattus norvegicus : Ppif (peptidylprolyl isomerase F)

Latest Assembly:

Human Genome Assembly GRCh37

NCBI Annotation Information:

Note: This gene encodes a 178 aa mature peptide that is found in the mitochondrion. It has been labeled 'cyclophilin D'. This same name has also been applied to a different cytoplasmic protein of 370 aa, which is represented by Entrez GeneID 5481, PPID. [10 Oct 2008]

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	10	81,480,435 - 81,488,305	+	NCBI
Human Genome Assembly HuRef	10	75,101,849 - 75,109,719	+	NCBI
Human Genome Assembly GRCh37	10	81,107,220 - 81,115,090	+	NCBI
Human Genome Assembly Build 36	10	80,777,226 - 80,785,096	+	NCBI
Human Cytogenetic Map	10	q22-q23		NCBI
Human Genome Assembly	10	80,777,225 - 80,785,093		NCBI