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Gene: Mafk (MAF bZIP transcription factor K) Rattus norvegicus

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Symbol:

Mafk

Name:

MAF bZIP transcription factor K

RGD ID:

628633

Description:

Orthologous to human MAFK (MAF bZIP transcription factor K); PARTICIPATES IN nuclear factor, erythroid 2 like 2 signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

transcription factor MafK; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian); v-maf musculoaponeurotic fibrosarcoma oncogene homolog K; v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	19,948,473 - 19,970,351 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	19,948,476 - 19,959,192 (-)	Ensembl				GRCr8
mRatBN7.2	12	14,834,628 - 14,856,414 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	14,832,249 - 14,858,888 (-)	Ensembl				mRatBN7.2
mRatBN7.2 Ensembl	12	14,833,984 - 14,837,048 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	15,643,621 - 15,654,344 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	16,267,374 - 16,278,097 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	15,292,794 - 15,303,525 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	16,923,989 - 16,934,706 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	16,923,990 - 16,934,706 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	18,914,796 - 18,936,523 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	15,312,420 - 15,323,137 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	16,593,511 - 16,604,228 (-)	NCBI		Celera
RGSC_v3.1	12	15,342,348 - 15,353,065 (-)	NCBI
Cytogenetic Map	12	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(E)-cinnamyl alcohol (ISO)

1,2-dimethylhydrazine (ISO)

1-chloro-2,4-dinitrobenzene (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

2-palmitoylglycerol (ISO)

4-(ethoxymethylene)-2-phenyloxazol-5-one (ISO)

6-propyl-2-thiouracil (EXP)

acrolein (ISO)

acrylamide (EXP,ISO)

alpha-hexylcinnamaldehyde (ISO)

alpha-pinene (ISO)

ammonium chloride (EXP)

amphetamine (EXP)

aristolochic acid A (ISO)

arsenous acid (ISO)

Bandrowski's base (ISO)

benzene (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

beta-naphthoflavone (EXP)

bis(2-chloroethyl) sulfide (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

caffeine (ISO)

chenodeoxycholic acid (ISO)

cinnamyl alcohol (ISO)

cisplatin (ISO)

clobetasol (ISO)

clofibrate (ISO)

cobalt dichloride (EXP,ISO)

copper(II) sulfate (ISO)

coumarin (ISO)

CU-O LINKAGE (ISO)

cyclosporin A (ISO)

DDE (ISO)

deoxycholic acid (ISO)

diarsenic trioxide (ISO)

diazinon (EXP)

Dibutyl phosphate (ISO)

dibutyl phthalate (EXP,ISO)

dieldrin (EXP)

diethyl phthalate (ISO)

diethylstilbestrol (EXP)

diisobutyl phthalate (ISO)

diisononyl phthalate (ISO)

dimercaprol (ISO)

dioxygen (ISO)

disulfiram (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

eugenol (ISO)

fluoranthene (ISO)

flutamide (EXP)

folic acid (ISO)

gentamycin (EXP)

glycochenodeoxycholic acid (ISO)

glycocholic acid (ISO)

glycodeoxycholic acid (ISO)

glyphosate (ISO)

hydroquinone O-beta-D-glucopyranoside (ISO)

isoeugenol (ISO)

kojic acid (ISO)

leflunomide (EXP)

lipopolysaccharide (ISO)

methamphetamine (EXP)

methoxychlor (EXP)

methylmercury chloride (ISO)

mono(2-ethylhexyl) phthalate (EXP)

N-methylformamide (ISO)

N-nitrosodiethylamine (EXP)

nefazodone (ISO)

nickel dichloride (EXP)

nickel sulfate (ISO)

nitrofen (EXP)

okadaic acid (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

paraquat (EXP,ISO)

pentachlorophenol (ISO)

perfluorooctanoic acid (EXP)

phenobarbital (ISO)

phenylephrine (EXP)

phenylmercury acetate (ISO)

reactive oxygen species (ISO)

SB 431542 (ISO)

senecionine (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

Soman (EXP)

tacrolimus hydrate (ISO)

tamoxifen (ISO)

tert-butyl hydroperoxide (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

trans-isoeugenol (ISO)

trichloroethene (EXP)

triphenyl phosphate (ISO)

triptonide (ISO)

urethane (ISO)

valdecoxib (EXP)

valproic acid (ISO)

xylitol (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of transcription by RNA polymerase II (ISO)

nervous system development (IDA)

regulation of DNA-templated transcription (IEA,ISO)

Cellular Component

nucleoplasm (ISO)

nucleus (IEA,ISO)

Molecular Function

DNA binding (IEA,ISO)

DNA-binding transcription factor activity (IEA,ISO)

DNA-binding transcription repressor activity, RNA polymerase II-specific (ISO)

protein binding (ISO)

RING-like zinc finger domain binding (IPI)

sequence-specific DNA binding (ISO)

transcription cis-regulatory region binding (IDA,ISO)

transcription coregulator binding (IPI)

Molecular Pathway Annotations Click to see Annotation Detail View

nuclear factor, erythroid 2 like 2 signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	The Nrf2 regulatory network provides an interface between redox and intermediary metabolism.	Hayes JD and Dinkova-Kostova AT, Trends Biochem Sci. 2014 Apr;39(4):199-218. doi: 10.1016/j.tibs.2014.02.002. Epub 2014 Mar 16.
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	The carboxy-terminal Neh3 domain of Nrf2 is required for transcriptional activation.	Nioi P, etal., Mol Cell Biol. 2005 Dec;25(24):10895-906.
5.	Histone acetyltransferase MOZ acts as a co-activator of Nrf2-MafK and induces tumour marker gene expression during hepatocarcinogenesis.	Ohta K, etal., Biochem J. 2007 Mar 15;402(3):559-66.
6.	GOA pipeline	RGD automated data pipeline
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
9.	The basic region and leucine zipper transcription factor MafK is a new nerve growth factor-responsive immediate early gene that regulates neurite outgrowth.	Torocsik B, etal., J Neurosci 2002 Oct 15;22(20):8971-80.

Additional References at PubMed

PMID:8622968	PMID:8887638	PMID:9150357	PMID:9240432	PMID:12220541	PMID:23332764

Genomics

Comparative Map Data

Mafk
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	19,948,473 - 19,970,351 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	19,948,476 - 19,959,192 (-)	Ensembl				GRCr8
mRatBN7.2	12	14,834,628 - 14,856,414 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	14,832,249 - 14,858,888 (-)	Ensembl				mRatBN7.2
mRatBN7.2 Ensembl	12	14,833,984 - 14,837,048 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	15,643,621 - 15,654,344 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	16,267,374 - 16,278,097 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	15,292,794 - 15,303,525 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	16,923,989 - 16,934,706 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	16,923,990 - 16,934,706 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	18,914,796 - 18,936,523 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	15,312,420 - 15,323,137 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	16,593,511 - 16,604,228 (-)	NCBI		Celera
RGSC_v3.1	12	15,342,348 - 15,353,065 (-)	NCBI
Cytogenetic Map	12	q11	NCBI

MAFK
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	1,530,702 - 1,543,043 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	1,530,702 - 1,543,049 (+)	Ensembl			hg38	GRCh38
GRCh37	7	1,570,338 - 1,582,679 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	1,536,894 - 1,549,205 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	7	1,343,608 - 1,354,151	NCBI
Celera	7	1,537,624 - 1,549,935 (+)	NCBI		Celera
Cytogenetic Map	7	p22.3	NCBI
HuRef	7	1,499,263 - 1,503,161 (+)	NCBI		HuRef
CHM1_1	7	1,569,960 - 1,582,262 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	7	1,642,830 - 1,655,171 (+)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	1,622,776 - 1,635,087 (+)	NCBI

Mafk
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	139,777,291 - 139,788,409 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	139,777,268 - 139,788,408 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	139,791,536 - 139,802,653 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	139,791,513 - 139,802,653 (+)	Ensembl			mm10	GRCm38
MGSCv37	5	140,267,490 - 140,278,606 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	140,044,010 - 140,055,126 (+)	NCBI		MGSCv36	mm8
Celera	5	136,846,479 - 136,857,581 (+)	NCBI		Celera
Cytogenetic Map	5	G2	NCBI
cM Map	5	78.81	NCBI

Mafk
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955460	9,155,713 - 9,167,291 (+)	Ensembl
ChiLan1.0	NW_004955460	9,155,713 - 9,167,291 (+)	NCBI	ChiLan1.0	ChiLan1.0

MAFK
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	6,480,254 - 6,492,566 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	54,804,956 - 54,817,267 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	1,778,862 - 1,791,163 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	1,902,411 - 1,909,774 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	1,904,031 - 1,909,774 (+)	Ensembl			panPan2	panpan1.1

MAFK
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	15,421,918 - 15,426,650 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	15,424,095 - 15,425,594 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	16,889,609 - 16,901,307 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	15,547,885 - 15,559,587 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	15,547,886 - 15,559,718 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	15,350,661 - 15,362,365 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	15,277,453 - 15,289,141 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	15,564,445 - 15,576,148 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Mafk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	143,353,784 - 143,364,317 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936754	1,651,704 - 1,656,549 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936754	1,652,412 - 1,656,570 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MAFK
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	1,030,858 - 1,033,671 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	3	1,023,366 - 1,034,855 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	1,138,008 - 1,149,711 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MAFK
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	28	20,057,386 - 20,070,020 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	28	20,060,001 - 20,061,170 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666090	1,647,542 - 1,659,816 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mafk
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624740	27,002,022 - 27,006,324 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624740	26,995,889 - 27,007,258 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Mafk
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	16	13,390,311 - 13,401,210 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Mafk
228 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	233
Count of miRNA genes:	153
Interacting mature miRNAs:	173
Transcripts:	ENSRNOT00000001720
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2312418	Kidm41	Kidney mass QTL 41	3.7	0.0001	kidney mass (VT:0002707)	single kidney wet weight to body weight ratio (CMO:0000622)	12	5921918	25247790	Rat
70213	Niddm27	Non-insulin dependent diabetes mellitus QTL 27	3.72		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	11200494	52308831	Rat
2306789	Ean6	Experimental allergic neuritis QTL 6	4.9		nervous system integrity trait (VT:0010566)	experimental autoimmune neuritis severity score (CMO:0001528)	12	1	29775522	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	3489416	48489416	Rat
1331739	Hrtrt14	Heart rate QTL 14	3.56232		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	12	1	38687564	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	18473041	52308831	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200497	52308831	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	15264248	52308831	Rat
61331	Eau2	Experimental allergic uveoretinitis QTL 2		0.0005	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	12	1	33700600	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	11743528	52308831	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
2293684	Bmd26	Bone mineral density QTL 26	4.4	0.0002	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	12	1	38635130	Rat
6893681	Bw109	Body weight QTL 109	2.3	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	12	1	28133365	Rat
1302792	Scl21	Serum cholesterol level QTL 21	3.8	0.0011	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	12	12233000	30490641	Rat
61404	Bw120	Body weight QTL 120	5.1		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	12	17464979	46784661	Rat
1300174	Bw15	Body weight QTL 15	2.93		body mass (VT:0001259)	body weight loss (CMO:0001399)	12	1	28606299	Rat
1331786	Kidm11	Kidney mass QTL 11	3.571		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	12	16187438	52308831	Rat
1331787	Rf41	Renal function QTL 41	2.998		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	12	1	33700556	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	16135029	52308831	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	16187438	51213550	Rat
1331763	Wbc2	White blood cell count QTL 2	3.162		leukocyte quantity (VT:0000217)	total white blood cell count (CMO:0000365)	12	11200494	52308831	Rat
61416	Pia4	Pristane induced arthritis QTL 4	8.4		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	12	18749469	36488809	Rat
7204484	Bp358	Blood pressure QTL 358		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	1	24849755	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	11200494	52308831	Rat
7387292	Kidm42	Kidney mass QTL 42	3.03	0.0004	kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	12	1	41361854	Rat
61421	Cia12	Collagen induced arthritis QTL 12	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	18749469	34312613	Rat
1298081	Cia25	Collagen induced arthritis QTL 25	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	2747694	47747694	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	18473041	52308831	Rat
2303568	Bw88	Body weight QTL 88	3		body mass (VT:0001259)	body weight (CMO:0000012)	12	1	28606299	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	3087180	48087180	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7243862	Mcs30	Mammary carcinoma susceptibility QTL 30	8.62		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	12	5633306	50633306	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	16135029	52308831	Rat
2293086	Iddm30	Insulin dependent diabetes mellitus QTL 30	3.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	7901625	33938215	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
1331755	Bp219	Blood pressure QTL 219	3.041		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	16187438	33700556	Rat

Markers in Region

BI284461

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	12	19,948,900 - 19,949,085 (+)	Marker Load Pipeline
mRatBN7.2	12	14,835,053 - 14,835,238 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	16,924,415 - 16,924,599	NCBI	Rnor6.0
Rnor_5.0	12	18,915,222 - 18,915,406	UniSTS	Rnor5.0
RGSC_v3.4	12	15,312,846 - 15,313,030	UniSTS	RGSC3.4
Celera	12	16,593,937 - 16,594,121	UniSTS
RH 3.4 Map	12	237.72	UniSTS
Cytogenetic Map	12	q11	UniSTS

Mafk

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	14,834,656 - 14,835,244 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	16,924,018 - 16,924,605	NCBI	Rnor6.0
Rnor_5.0	12	18,914,825 - 18,915,412	UniSTS	Rnor5.0
RGSC_v3.4	12	15,312,449 - 15,313,036	UniSTS	RGSC3.4
Celera	12	16,593,540 - 16,594,127	UniSTS
Cytogenetic Map	12	q11	UniSTS

UniSTS:257105

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	12	19,950,843 - 19,951,810 (+)	Marker Load Pipeline
mRatBN7.2	12	14,836,995 - 14,837,963 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	16,926,357 - 16,927,324	NCBI	Rnor6.0
Rnor_5.0	12	18,917,164 - 18,918,131	UniSTS	Rnor5.0
RGSC_v3.4	12	15,314,788 - 15,315,755	UniSTS	RGSC3.4
Celera	12	16,595,879 - 16,596,846	UniSTS
Cytogenetic Map	12	q11	UniSTS

UniSTS:274182

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	14,836,595 - 14,837,978 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	16,925,957 - 16,927,339	NCBI	Rnor6.0
Rnor_5.0	12	18,916,764 - 18,918,146	UniSTS	Rnor5.0
RGSC_v3.4	12	15,314,388 - 15,315,770	UniSTS	RGSC3.4
Celera	12	16,595,479 - 16,596,861	UniSTS
Cytogenetic Map	12	q11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	161	91	90	59	92	59	6	356	192	11	140	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_145673	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006248915	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089073	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF461686	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC070906	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000001720 ⟹ ENSRNOP00000001720

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	19,948,476 - 19,959,192 (-)	Ensembl
mRatBN7.2 Ensembl	12	14,834,630 - 14,858,888 (-)	Ensembl
Rnor_6.0 Ensembl	12	16,923,990 - 16,934,706 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000094745

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	14,834,443 - 14,839,924 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000098949

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	14,833,984 - 14,837,048 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000099198

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	19,948,476 - 19,953,088 (-)	Ensembl
mRatBN7.2 Ensembl	12	14,834,634 - 14,856,489 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000117128

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	14,832,249 - 14,845,488 (-)	Ensembl

RefSeq Acc Id:

NM_145673 ⟹ NP_663706

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	19,948,475 - 19,959,192 (-)	NCBI
mRatBN7.2	12	14,834,628 - 14,845,345 (-)	NCBI
Rnor_6.0	12	16,923,989 - 16,934,706 (-)	NCBI
Rnor_5.0	12	18,914,796 - 18,936,523 (-)	NCBI
RGSC_v3.4	12	15,312,420 - 15,323,137 (-)	RGD
Celera	12	16,593,511 - 16,604,228 (-)	RGD

Sequence:

show sequence

CCGGGACTTGTTGTTCTTTGCCGAGTCGGAACGAGTAGTCCGAAGCGCGCAGGCGGAGACGGCG
ACTGAGGGGAGCGCGAGAGCAGAAGCGCGCGTGAAGAGTGCGTGTCTACAGGAGCCGCCGCGCC
CGGCCCCGCGCGCGACCCGGCTACGATTTCCTGGTGGTTCCGTCCTGGTGACAGGGCCCGGGTT
ATGACGACTAATCCCAAGCCCAACAAGACATTGAAGGTCAAGAAGGAGGCGGGCGAGAACGCCC
CTGTTCTTAGCGACGATGAGCTGGTGTCCATGTCGGTGCGGGAGCTGAACCAGCACCTGCGGGG
GCTCACCAAGGAGGAGGTAACTCGGCTGAAGCAGCGGCGGCGCACACTCAAGAACCGAGGCTAC
GCCGCCAGCTGTCGCATCAAGCGCGTGACACAGAAGGAGGAGCTGGAGCGGCAGCGGGTGGAGC
TGCAGCAGGAGGTAGAGAAGCTGGCTCGTGAGAACAGCAGCATGCGTCTGGAGCTGGATGCCCT
GCGCTCCAAGTACGAGGCCCTGCAGACCTTCGCACGCACCGTGGCCCGAGGGCCTGTCACACCC
ACCAAGGTGGCCACCACCAGTGTCATCACCATCGTCAAATCCGCAGAGCTCTCCTCCACCTCTG
TGCCCTTCTCAGCGGCCTCCTAGTGTCTGCTGGGGCCGGGCAGGGTGCGGGCAGTGGCACAGCC
CTCATGCCTATCCCAGGCTCCCTGGTACAGATTCCTCATGTCTACCTGCCCACTGTGGACCCTG
CAGGGCTGAGGGCAGGGACGGCAGGGACAGGCAGATGCAGGATAAAAGGGAAGCTCTCATGAGC
CAGTGCCACAAGCAACCCCCACTCACATCTCTCCTTCCCCTGGGGGTACGTCTCTAGGAGCTGA
CAGGAACCACACGGGCAACCGCGATGAACAACTCTAGGCCTCTGTGGCAGAGTGTGAGGACTCA
GTCTTCCACTTCTCCGGTGCCTGCTTATCAGCGTCATCGGTGCCGTCCCCTCTAAGGGCCTCCA
GCTGGGTTGGACACCATCTGTCTGTCACTTCTGGGCTCTGGCCTTCCTGTCCTTACTAAAGGGC
GCTACAACCTGCTTTAGCCCTTAGGTAGAGCCAGGCCCATGTCCTGGGAAACAGTTCCTGATAT
AGCCACTTGCAGGGGCTAATGTATGTGTTCCTGTGTGTACACAGGCTACCATCACAGCCTGTGA
AGACCGGAAACTGCTGGCCAAGTGGGAGAGCCTGGCCGGTATGTGTGCTGAGGGTTACACAAGT
GTCATGGAGTGTCCCTGGAAGTCTGGTAGGCTGCACCCCATTGTGGTGCAGGGGCCACCTGTCC
ACAGAGCCAGCAAACAGCCAGGCTCGGGTTCTCTGGGCCTTAGCAGAGGGGAGAGGCTGGAGAG
GAGCAGGGGAAGCCTGAGAGATGCTAAGGGGTATGTCGGTGGCGTGTGTGTGTTGTTGCGGAAA
GAACAGGAATGAAGTAGACAGGGATAGTGTGGAAGCCGAGGTCCAGGGGATGTGGAAGAGGCCG
AGAGGAATACTGTGGAGGGACAGAGACGACTTCTGGAGGGCCTTATGCACATAGCCATTGTGGG
CAGGTCGGCAAGGACCCCAGGCAGACTATAGGTCACAAATACTCTGCAACTTTGGTGTCCAATT
GTTACCTGCCTTTTCCTCCTTCATAGCACTCTGGGGCCACTGGCCATCTTGGTTTTTTTTAACT
GAAGGAATTGTGTCCTCCAGATCCTGGGGAATATGGTGGACAGGGAGTCAGGGGCAGGCTGAAC
TACAGCCAGGCACTTAGAAAGCACTGTTGGAACCATAGCCTTGGTAGGTAATCCATATTGGATA
TCAATAAGGACCATGGATATTTAAAGAGAGAAGATATATATATATATATAATTATACACACATT
TTATCGTACAGATTTTTCATAACAATTTTCTTTCCCAGTTTGATACTGTAGATCTTTATTAATG
CAGAGTAGGTTGGACAGTGGGGTGGGGAACGGAGGCCCAGGGTGCCAACAGCCTCCCTCAGTCT
TTCTGTGGTGGTGCTGGCAGGCCGGGTCACTGGATGAGTGGTCTCCAGGGTAGGCAGGTGACCA
CTGACTGGCTTGCTGCCCGCTCCTGGCCTCTGGTGGTCCTCCTGGGTGGAGGCCCCATACTCTT
GGCGGCCAGGGGAGACAGGGCTGTCAGTACCACTGGAGCACCTGCAGAGGACACCTGCCAGGAG
GGGGCTGGGAAGGGTGTGAGCATGCCCCATGGCTTCGTGTCACTGAAATTTCATTGTCACAACT
TAATAATATATGGATGTTTTTATTTAAAGATAAAAGTGAGTTTTCTGTCTTGTTCCTCTGACTT
CTTAAAGCAAGCTTTAACTATTTCAAAAGGTGTCAGGGACACATGCCGATCATGCCGAGGCCTG
GCATCCTCAGCCGCCTGCCACTTGGCAATTTCATTTCAATATTTATTTTTTTTTTGTGCTTTTT
TTCCCCCATGTTATAAATTATTGAGAAGAGATCAAGATCACAGACTGTTGGCCCCGTCTGCACC
CTGCCTCATGGCCACCACCTAATTTATTGCTGTACATGTCGCCGTGACTGCTTTTGTATCTTTG
CAATAAAGAATTTCCTGTTTGAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006248915 ⟹ XP_006248977

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	19,948,473 - 19,957,286 (-)	NCBI
mRatBN7.2	12	14,834,628 - 14,843,437 (-)	NCBI
Rnor_6.0	12	16,923,989 - 16,931,564 (-)	NCBI
Rnor_5.0	12	18,914,796 - 18,936,523 (-)	NCBI

Sequence:

show sequence

TCCTCTGACCTTCACACCCACTTTGGCAAGTACACACACACACACACACACAGTCTGGACTTAG
CTGTTTCCTGGGCACATCCCCACTGAAACATGGAGTAGAAGGTGACTGAAGCCCCAGGACCACC
AGGGATGGCACAGAGCCCTAACACGGACCGGGTATCAGAGAGGCCACTCAGTCAGTCAGGGAGA
GGAGGTCAGGTTAGAGGCAGAAGGAGGGCAGCCACAGTTAAGGGAGGTGTGCCATGCAGCCTGC
TGTCAGCCTCGAAGCTGCTTGAGTCACCTCTGCATGTAACTGGGATGACACAGCTTCCTGAGAT
TGCAAATGCAAGGTGACCAGACGTCCTCTAGGCTAGGCAGACAGTTGTGGCTTATGGGAGGGCA
GCCAGCCAGCCAGAGCTGGGTGGAGATGCCCAGCCACGCTCTGTGGGAGGACAGCAAACTGAAA
TCTTAGTGGTCTGCAGTGGCAGGAGCTCATTGGACCAGCTGTGGTGTGTGTTTCATCAGCATGT
GGCCACTGTATGTCGGTAATGTGTTAGCTCCATGTACCCTCAGGGTCCTGGAAAGGGTACTTGG
CTCTGGGTATTTGTGAGAAGCTCTTGAGCAGAGGTGGCCACATCCTTAGTGGCTTTAGGTTCTG
TGGCTCTCAGCTATCTGGGGCTTGAACCTGTTTTTTTGGACAGAATAGGTCTTTCCCTCTCCTC
ATCACCCACCCTGCTCCCTTCCCCCATTCTGGGAGACCAGGAACCTGAAGAGCACACATCCTGG
TCAGCTGGATTGGGGGCTGCAGTTGCTGTTACTCTGCGGAACCCCTGGGTTGGTATCACAGTTG
CAGCAGAGTGAGGTGTGTGACCCAGGTTACGCACTACCCCGGGGAACATGGAGACCCTCTGAGA
CTTTTTCTGGTCCACTGTTGCACTAGTAGCAAGGTCTCTGTAGTTCCCTATCTGTTTCTCCTTT
GGACCTGGCCATGGTCCTCTTTGCTGTGTGCTGGGACTGCCAGGATGTTGTGCAGGAGGGAGGT
GAGGCTGTAAATGCCCCCAGTAGTGCAGTCAATGCAGTGTGGTGCTGGGGAACTGCTTCCGGAG
TGAAAGTAGGATAGGAGATGCATGCCTGGCCCCCCTCCCCTCCGGAGAAAGACAGTCTGCTAGG
GCCTGGGCTACCTGCTGTCTCTGGGCGCCAGGCTGGATTCCCACGCTCTGTGGTGTGCCTCCCT
GCTCGTTATGCACAGGGCGTCTTCTACCCCAGTCCATCCTGAAATGGAAGGAGCTGGGCAGAGG
AGGGGGATCTTCCTAAGTTGTCCAGGTTGACTTTGAACACACTCTGTAGCCCAGGCTGGCCTTG
AACTTGTAAACTTCCCAAGTTCTAGGATGACAGACCTGGTTTGGCCTTTGATGGGTAGGGTGGG
ACTGTACCCATTGGCTTGGTGTATAAGGGACACACTGAGTTGCTGAAAATCTCTGTCCCTTAGA
TCGTCCCCCCATGATTGCCACCAGGCAGAAGGGCATGCCTCTGTCTGACTCAGGGCCAACGTGG
ACCTCACCTTTCACCTGGACAGACTTCTACAATGTTAGTCACGAAGGCTGCAGTCAGAGTTAGT
TTGACAAGGGGTACAGGTGCTCCTGCTGAACAGAGTTCCAGGAACTGGACAGGGTGGGCTGGGG
TAAACACATTAGCTCAGTATAAGTCAGGACTCCTGAGTGGGGGCTTCTCACTACTTGTCGTCTC
TGGGATCTTTTCGCTCACCCTCTTTTTCTGAGGAAATGACCCCGAGCATTGGGAGGTGTTGTCA
TTTGTCCATGGCTCTTGGGGTTTACTTATTTTTAAGCCAGCTGAGGACTGAGGAAGGGTCCCTG
AATGCAGCAGAAGCCCATAAAGAGGGTGGACATGGAGAGAGCCAGGGAGGGGCCCTTCCTGCTG
GCCAGGTGGCCTCCATCCAGTGGTCAGTTGACTCTCATGGGGTCACCTGGGGGCGTAAGCCCCT
GCCCTGTGCACATCCTGGCCACCCGGTGTCACGGTACCATCACTATGGGGGTGGGGAGATTCCC
GCCCGTCACTAAGCGCTGGCCTGCACGTCTCAGCACCCTTGGGTCTGAGTTGAGTCCCCCTTCT
TCCCCGGCACCTTCCTTTTCCGCTGGCAGTGGCCCCTGGGGCCCGTGAGCATGCGGGTGGGAGG
GGTGTCCTTGTGTGGGAATGTGAGCCGGCTCTGTAAACAGCCCGTGACTCACCACATAGCTATG
TCACTGACGCTGGGGTTGCAAGTTGGAAGAGATGCCCAACCCCTCCTCCCTCCTTACACGGAAA
ACTTTCTCAGGGCTCCTAGGCGCCTGGCTTCTGAGAGCTCCTAATGGAGCTAAGGAAGCCCATG
ACTTCTCTGGTGCCGCTGTTCCCTAGCTGGGGCTGGAAGGGGTCTGTGGATACTACTTTGCCCA
CATCCCCATGTGATCTCTTATCAACAGTAGATCACCCCGACAAGCCCTTGTCCATCTCAGGTCC
CAGGGGATACTGTGACAGGTCCATGCTGCTTTACCTAAGCTTCCTGGCCCTGCCCCTGTCCTGG
TCTGCTGACTGCCTACTGAGTGTGACCCGTACTGTCACCAGGGTACTACATTCATTACCAGAGT
CAGTACCTTGTCTCTCGATGGTGGCTTCCTGGCAGTAAGGGTGGTAGGCAGTGGAGACAGGATC
CCATCAGAGGTGAATCACAGGGTGGAGAGATGGAGCCTACAGGTCCCCCACATTTGTGGGGGAA
GGTACAGTGGAGGTCATCCACTGTCTTTTTCATACCTGTTCTCCACATTCTTCTTTTGTGTGAT
TTCCCTAATGTTCCCTGTTCTGTGCCCATCTTTGTCAGGGTTTGAAATACAAGAGGTAGGGGTG
TATCCCACCAAGAGCTGTCCCTGCCCCTCTTACTCCTTCCTCAATTTGTCAGGGAATTGAGTGG
TTTTGTTTACTGCCTGAGAACCTCGTGTTGTCTTTCTGCACAGGCTTGACCCACAAGTCCCAAA
TGCTTTTGGGCTTCTCTGTTGCCATGGCAACTGTGGGGGGTTGGCTACATCCCAGAGTCGTCAT
GGCAACTATCAGAGGGGAATCATGCTTGGGATGCTTTGGCTGGCTTTTTCATGAATGATGAGGG
TGTGTGACACAATGCAGACTGGAGAATGAGAAGGGCGGGCAAGGGGGCTGGCGGGTTGGCCATG
GGGACAGGGCCTGCCAGACAGCCCGGTAAGTCTGCCAGGTGGCTGGAGTTCTCTGCTGGTGTCT
CTGGCTGGATCCTCTGAACCTACTACCCACCAGTAGCCCCCCACCCTACCCATAGGGACCTTGG
GGTCACTCTGAAGGGCTGGGATGGCCTGGGAGGAGTGGTGATGTCACAGCTGCAGTGTCCTTCA
CGCTGCTACGATTTCCTGGTGGTTCCGTCCTGGTGACAGGGCCCGGGTTATGACGACTAATCCC
AAGCCCAACAAGACATTGAAGGTCAAGAAGGAGGCGGGCGAGAACGCCCCTGTTCTTAGCGACG
ATGAGCTGGTGTCCATGTCGGTGCGGGAGCTGAACCAGCACCTGCGGGGGCTCACCAAGGAGGA
GGTAACTCGGCTGAAGCAGCGGCGGCGCACACTCAAGAACCGAGGCTACGCCGCCAGCTGTCGC
ATCAAGCGCGTGACACAGAAGGAGGAGCTGGAGCGGCAGCGGGTGGAGCTGCAGCAGGAGGTAG
AGAAGCTGGCTCGTGAGAACAGCAGCATGCGTCTGGAGCTGGATGCCCTGCGCTCCAAGTACGA
GGCCCTGCAGACCTTCGCACGCACCGTGGCCCGAGGGCCTGTCACACCCACCAAGGTGGCCACC
ACCAGTGTCATCACCATCGTCAAATCCGCAGAGCTCTCCTCCACCTCTGTGCCCTTCTCAGCGG
CCTCCTAGTGTCTGCTGGGGCCGGGCAGGGTGCGGGCAGTGGCACAGCCCTCATGCCTATCCCA
GGCTCCCTGGTACAGATTCCTCATGTCTACCTGCCCACTGTGGACCCTGCAGGGCTGAGGGCAG
GGACGGCAGGGACAGGCAGATGCAGGATAAAAGGGAAGCTCTCATGAGCCAGTGCCACAAGCAA
CCCCCACTCACATCTCTCCTTCCCCTGGGGGTACGTCTCTAGGAGCTGACAGGAACCACACGGG
CAACCGCGATGAACAACTCTAGGCCTCTGTGGCAGAGTGTGAGGACTCAGTCTTCCACTTCTCC
GGTGCCTGCTTATCAGCGTCATCGGTGCCGTCCCCTCTAAGGGCCTCCAGCTGGGTTGGACACC
ATCTGTCTGTCACTTCTGGGCTCTGGCCTTCCTGTCCTTACTAAAGGGCGCTACAACCTGCTTT
AGCCCTTAGGTAGAGCCAGGCCCATGTCCTGGGAAACAGTTCCTGATATAGCCACTTGCAGGGG
CTAATGTATGTGTTCCTGTGTGTACACAGGCTACCATCACAGCCTGTGAAGACCGGAAACTGCT
GGCCAAGTGGGAGAGCCTGGCCGGTATGTGTGCTGAGGGTTACACAAGTGTCATGGAGTGTCCC
TGGAAGTCTGGTAGGCTGCACCCCATTGTGGTGCAGGGGCCACCTGTCCACAGAGCCAGCAAAC
AGCCAGGCTCGGGTTCTCTGGGCCTTAGCAGAGGGGAGAGGCTGGAGAGGAGCAGGGGAAGCCT
GAGAGATGCTAAGGGGTATGTCGGTGGCGTGTGTGTGTTGTTGCGGAAAGAACAGGAATGAAGT
AGACAGGGATAGTGTGGAAGCCGAGGTCCAGGGGATGTGGAAGAGGCCGAGAGGAATACTGTGG
AGGGACAGAGACGACTTCTGGAGGGCCTTATGCACATAGCCATTGTGGGCAGGTCGGCAAGGAC
CCCAGGCAGACTATAGGTCACAAATACTCTGCAACTTTGGTGTCCAATTGTTACCTGCCTTTTC
CTCCTTCATAGCACTCTGGGGCCACTGGCCATCTTGGTTTTTTTTAACTGAAGGAATTGTGTCC
TCCAGATCCTGGGGAATATGGTGGACAGGGAGTCAGGGGCAGGCTGAACTACAGCCAGGCACTT
AGAAAGCACTGTTGGAACCATAGCCTTGGTAGGTAATCCATATTGGATATCAATAAGGACCATG
GATATTTAAAGAGAGAAGATATATATATATATATAATTATACACACATTTTATCGTACAGATTT
TTCATAACAATTTTCTTTCCCAGTTTGATACTGTAGATCTTTATTAATGCAGAGTAGGTTGGAC
AGTGGGGTGGGGAACGGAGGCCCAGGGTGCCAACAGCCTCCCTCAGTCTTTCTGTGGTGGTGCT
GGCAGGCCGGGTCACTGGATGAGTGGTCTCCAGGGTAGGCAGGTGACCACTGACTGGCTTGCTG
CCCGCTCCTGGCCTCTGGTGGTCCTCCTGGGTGGAGGCCCCATACTCTTGGCGGCCAGGGGAGA
CAGGGCTGTCAGTACCACTGGAGCACCTGCAGAGGACACCTGCCAGGAGGGGGCTGGGAAGGGT
GTGAGCATGCCCCATGGCTTCGTGTCACTGAAATTTCATTGTCACAACTTAATAATATATGGAT
GTTTTTATTTAAAGATAAAAGTGAGTTTTCTGTCTTGTTCCTCTGACTTCTTAAAGCAAGCTTT
AACTATTTCAAAAGGTGTCAGGGACACATGCCGATCATGCCGAGGCCTGGCATCCTCAGCCGCC
TGCCACTTGGCAATTTCATTTCAATATTTATTTTTTTTTTGTGCTTTTTTTCCCCCATGTTATA
AATTATTGAGAAGAGATCAAGATCACAGACTGTTGGCCCCGTCTGCACCCTGCCTCATGGCCAC
CACCTAATTTATTGCTGTACATGTCGCCGTGACTGCTTTTGTATCTTTGCAATAAAGAATTTCC
TGTTTGA

hide sequence

RefSeq Acc Id:

XM_039089073 ⟹ XP_038945001

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	19,948,473 - 19,970,351 (-)	NCBI
mRatBN7.2	12	14,834,628 - 14,856,414 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_663706	(Get FASTA)	NCBI Sequence Viewer
	XP_006248977	(Get FASTA)	NCBI Sequence Viewer
	XP_038945001	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH70906	(Get FASTA)	NCBI Sequence Viewer
	AAM73877	(Get FASTA)	NCBI Sequence Viewer
	EDL89750	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000104040.1
	ENSRNOP00000111858
	ENSRNOP00000111858.1

RefSeq Acc Id:	NP_663706 ⟸ NM_145673
- UniProtKB:	Q6IRI7 (UniProtKB/TrEMBL), Q8K4B3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTTNPKPNKTLKVKKEAGENAPVLSDDELVSMSVRELNQHLRGLTKEEVTRLKQRRRTLKNRGY AASCRIKRVTQKEELERQRVELQQEVEKLARENSSMRLELDALRSKYEALQTFARTVARGPVTP TKVATTSVITIVKSAELSSTSVPFSAAS hide sequence

RefSeq Acc Id:	XP_006248977 ⟸ XM_006248915
- Peptide Label:	isoform X1
- UniProtKB:	Q6IRI7 (UniProtKB/TrEMBL), Q8K4B3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTTNPKPNKTLKVKKEAGENAPVLSDDELVSMSVRELNQHLRGLTKEEVTRLKQRRRTLKNRGY AASCRIKRVTQKEELERQRVELQQEVEKLARENSSMRLELDALRSKYEALQTFARTVARGPVTP TKVATTSVITIVKSAELSSTSVPFSAAS hide sequence

Ensembl Acc Id:

ENSRNOP00000001720 ⟸ ENSRNOT00000001720

RefSeq Acc Id:	XP_038945001 ⟸ XM_039089073
- Peptide Label:	isoform X1
- UniProtKB:	Q6IRI7 (UniProtKB/TrEMBL), Q8K4B3 (UniProtKB/TrEMBL)

Protein Domains

bZIP

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6IRI7-F1-model_v2	AlphaFold	Q6IRI7	1-156	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698462

Promoter ID:

EPDNEW_R8987

Type:

multiple initiation site

Name:

Mafk_1

Description:

MAF bZIP transcription factor K

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	12	16,934,739 - 16,934,799	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:628633	AgrOrtholog
BioCyc Gene	G2FUF-19906	BioCyc
Ensembl Genes	ENSRNOG00000001277	Ensembl
	ENSRNOG00000065794	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000001720	ENTREZGENE
	ENSRNOT00000001720.6	UniProtKB/TrEMBL
	ENSRNOT00000099198.2	UniProtKB/TrEMBL
Gene3D-CATH	1.20.5.170	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7103075	IMAGE-MGC_LOAD
InterPro	bZIP_sf	UniProtKB/TrEMBL
	Euk_TF_DNA_bd	UniProtKB/TrEMBL
	TF_bZIP	UniProtKB/TrEMBL
	TF_Maf	UniProtKB/TrEMBL
	Transciption_factor_Maf	UniProtKB/TrEMBL
KEGG Report	rno:246760	UniProtKB/TrEMBL
MGC_CLONE	MGC:91461	IMAGE-MGC_LOAD
NCBI Gene	246760	ENTREZGENE
PANTHER	PTHR10129	UniProtKB/TrEMBL
	PTHR10129:SF26	UniProtKB/TrEMBL
Pfam	bZIP_Maf	UniProtKB/TrEMBL
PhenoGen	Mafk	PhenoGen
PROSITE	BZIP	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000001277	RatGTEx
	ENSRNOG00000065794	RatGTEx
RNAcentral	URS00022AEB3F	RNACentral
	URS00022AF55F	RNACentral
	URS00022B2CE2	RNACentral
	URS00022B4018	RNACentral
	URS00022B5215	RNACentral
SMART	BRLZ	UniProtKB/TrEMBL
Superfamily-SCOP	Euk_transcr_DNA	UniProtKB/TrEMBL
	SSF57959	UniProtKB/TrEMBL
UniProt	A0ABK0LKJ2_RAT	UniProtKB/TrEMBL
	A6K1U2_RAT	UniProtKB/TrEMBL
	Q6IRI7	ENTREZGENE, UniProtKB/TrEMBL
	Q8K4B3	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-05-18	Mafk	MAF bZIP transcription factor K	Mafk	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-07-18	Mafk	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K	Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-10-30	Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)	Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)			Symbol and Name status set to approved	1299863	APPROVED
2003-02-27	Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed in immature neurons	628386
gene_process	involved in neuronal outgrowth and maintenance	628386
gene_process	regulator of neuronal differentiation	628386
gene_product	member of the Maf family of basic region and leucine zipper transciption factors	628386
gene_product	member of the Maf family has a leucine zipper transcriptional repressor	628386
gene_regulation	expression in immature neurons is induced by NGF	628386

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

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Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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RGD Manual Annotations