Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | ISO | Necab2 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of NECAB2 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | ISO | Necab2 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of NECAB2 mRNA] | CTD | PMID:22206623 | 17beta-estradiol 3-benzoate | decreases methylation | EXP | | 6480464 | estradiol 3-benzoate results in decreased methylation of NECAB2 promoter | CTD | PMID:27415467 | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Necab2 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | Necab2 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | 4,4'-sulfonyldiphenol | decreases expression | ISO | Necab2 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of NECAB2 mRNA | CTD | PMID:30951980 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of NECAB2 mRNA | CTD | PMID:24780913 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of NECAB2 mRNA | CTD | PMID:31881176 | acrylamide | decreases expression | ISO | NECAB2 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of NECAB2 mRNA | CTD | PMID:32763439 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of NECAB2 mRNA | CTD | PMID:16483693 | arsenous acid | decreases expression | ISO | NECAB2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of NECAB2 mRNA | CTD | PMID:20458559 | benzo[a]pyrene | decreases methylation | ISO | NECAB2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of NECAB2 3' UTR more ... | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | NECAB2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of NECAB2 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | increases methylation | ISO | Necab2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased methylation of NECAB2 exon and Benzo(a)pyrene results in increased methylation of NECAB2 intron | CTD | PMID:27901495 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | NECAB2 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of NECAB2 mRNA | CTD | PMID:31163220 | bisphenol A | decreases methylation | ISO | Necab2 (Mus musculus) | 6480464 | bisphenol A results in decreased methylation of NECAB2 promoter | CTD | PMID:27312807 | bisphenol A | decreases expression | ISO | Necab2 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of NECAB2 mRNA | CTD | PMID:32156529 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of NECAB2 mRNA | CTD | PMID:30816183 and PMID:34947998 | bisphenol F | decreases expression | ISO | Necab2 (Mus musculus) | 6480464 | bisphenol F results in decreased expression of NECAB2 mRNA | CTD | PMID:30951980 | butanal | decreases expression | ISO | NECAB2 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of NECAB2 mRNA | CTD | PMID:26079696 | carbon nanotube | decreases expression | ISO | Necab2 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | cisplatin | multiple interactions | ISO | NECAB2 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of NECAB2 mRNA | CTD | PMID:27392435 | cocaine | affects expression | EXP | | 6480464 | Cocaine affects the expression of NECAB2 mRNA | CTD | PMID:20187946 | cocaine | decreases expression | EXP | | 6480464 | Cocaine results in decreased expression of NECAB2 protein | CTD | PMID:25100957 | diarsenic trioxide | decreases expression | ISO | NECAB2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of NECAB2 mRNA | CTD | PMID:20458559 | doxorubicin | increases expression | ISO | NECAB2 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of NECAB2 mRNA | CTD | PMID:30031762 | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of NECAB2 mRNA | CTD | PMID:29391264 | ethylparaben | decreases expression | ISO | NECAB2 (Homo sapiens) | 6480464 | ethyl-p-hydroxybenzoate results in decreased expression of NECAB2 mRNA | CTD | PMID:37690743 | flavonoids | increases expression | EXP | | 6480464 | Flavonoids results in increased expression of NECAB2 mRNA | CTD | PMID:18035473 | folic acid | multiple interactions | ISO | Necab2 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of NECAB2 mRNA] | CTD | PMID:22206623 | GW 4064 | increases expression | ISO | Necab2 (Mus musculus) | 6480464 | GW 4064 results in increased expression of NECAB2 mRNA | CTD | PMID:26655953 | ochratoxin A | increases expression | EXP | | 6480464 | ochratoxin A results in increased expression of NECAB2 mRNA | CTD | PMID:18417182 and PMID:37162024 | ochratoxin A | decreases methylation | EXP | | 6480464 | ochratoxin A results in decreased methylation of NECAB2 gene | CTD | PMID:37162024 | ozone | multiple interactions | ISO | Necab2 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of NECAB2 mRNA | CTD | PMID:34911549 | ozone | increases expression | ISO | Necab2 (Mus musculus) | 6480464 | Ozone results in increased expression of NECAB2 mRNA | CTD | PMID:33026818 | paracetamol | affects expression | ISO | Necab2 (Mus musculus) | 6480464 | Acetaminophen affects the expression of NECAB2 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of NECAB2 mRNA | CTD | PMID:30723492 | PCB138 | multiple interactions | ISO | Necab2 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | pentanal | decreases expression | ISO | NECAB2 (Homo sapiens) | 6480464 | pentanal results in decreased expression of NECAB2 mRNA | CTD | PMID:26079696 | pirinixic acid | multiple interactions | ISO | Necab2 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of NECAB2 mRNA | CTD | PMID:19710929 | propanal | decreases expression | ISO | NECAB2 (Homo sapiens) | 6480464 | propionaldehyde results in decreased expression of NECAB2 mRNA | CTD | PMID:26079696 | rotenone | increases expression | ISO | NECAB2 (Homo sapiens) | 6480464 | Rotenone results in increased expression of NECAB2 mRNA | CTD | PMID:29955902 | silicon dioxide | decreases expression | ISO | NECAB2 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of NECAB2 mRNA | CTD | PMID:25895662 | sodium arsenite | decreases expression | ISO | NECAB2 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of NECAB2 mRNA | CTD | PMID:29301061 | sulforaphane | increases expression | ISO | NECAB2 (Homo sapiens) | 6480464 | sulforaphane results in increased expression of NECAB2 mRNA | CTD | PMID:31838189 | sunitinib | increases expression | ISO | NECAB2 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of NECAB2 mRNA | CTD | PMID:31533062 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of NECAB2 mRNA | CTD | PMID:34492290 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of NECAB2 mRNA | CTD | PMID:33387578 | trichostatin A | decreases expression | ISO | NECAB2 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of NECAB2 mRNA | CTD | PMID:24935251 | trimellitic anhydride | decreases expression | ISO | Necab2 (Mus musculus) | 6480464 | trimellitic anhydride results in decreased expression of NECAB2 mRNA | CTD | PMID:19042947 | valproic acid | affects expression | ISO | Necab2 (Mus musculus) | 6480464 | Valproic Acid affects the expression of NECAB2 mRNA | CTD | PMID:17292431 | valproic acid | increases methylation | ISO | NECAB2 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of NECAB2 gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | NECAB2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of NECAB2 mRNA | CTD | PMID:25979313 | zinc sulfate | increases expression | ISO | NECAB2 (Homo sapiens) | 6480464 | Zinc Sulfate results in increased expression of NECAB2 mRNA | CTD | PMID:19013360 | |