Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Strn3 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Strn3 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of STRN3 mRNA | CTD | PMID:22206623 | Strn3 | Rat | 17beta-estradiol | decreases expression | ISO | STRN3 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of STRN3 mRNA | CTD | PMID:19167446 | Strn3 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | STRN3 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | Strn3 | Rat | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Strn3 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:31388691 | Strn3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Strn3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of STRN3 mRNA | CTD | PMID:24058054 and PMID:24680724 | Strn3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of STRN3 mRNA | CTD | PMID:32109520 | Strn3 | Rat | 2,4,6-tribromophenol | decreases expression | ISO | STRN3 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | Strn3 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of STRN3 mRNA | CTD | PMID:21346803 | Strn3 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of STRN3 mRNA | CTD | PMID:21346803 | Strn3 | Rat | 2-methylcholine | affects expression | ISO | STRN3 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of STRN3 mRNA | CTD | PMID:21179406 | Strn3 | Rat | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | STRN3 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in decreased expression of STRN3 protein | CTD | PMID:31675489 | Strn3 | Rat | aflatoxin B1 | increases expression | ISO | Strn3 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of STRN3 mRNA | CTD | PMID:19770486 | Strn3 | Rat | aflatoxin B1 | decreases methylation | ISO | STRN3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of STRN3 gene | CTD | PMID:27153756 | Strn3 | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of STRN3 mRNA | CTD | PMID:38685447 | Strn3 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of STRN3 mRNA | CTD | PMID:16483693 | Strn3 | Rat | aristolochic acid A | multiple interactions | EXP | | 6480464 | [aristolochic acid I co-treated with aristolochic acid II] results in decreased expression of STRN3 mRNA | CTD | PMID:23912714 | Strn3 | Rat | Aroclor 1254 | decreases expression | ISO | Strn3 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of STRN3 mRNA | CTD | PMID:23650126 | Strn3 | Rat | arsenite(3-) | multiple interactions | ISO | STRN3 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to STRN3 mRNA] | CTD | PMID:32406909 | Strn3 | Rat | arsenous acid | increases expression | ISO | STRN3 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of STRN3 mRNA | CTD | PMID:20458559 | Strn3 | Rat | benzo[a]pyrene | increases methylation | ISO | STRN3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of STRN3 promoter | CTD | PMID:27901495 | Strn3 | Rat | benzo[a]pyrene | affects methylation | ISO | STRN3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of STRN3 intron | CTD | PMID:30157460 | Strn3 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | STRN3 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | Strn3 | Rat | beta-lapachone | decreases expression | ISO | STRN3 (Homo sapiens) | 6480464 | beta-lapachone results in decreased expression of STRN3 mRNA | CTD | PMID:38218311 | Strn3 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of STRN3 mRNA | CTD | PMID:25181051 and PMID:30816183 | Strn3 | Rat | bisphenol A | decreases expression | ISO | STRN3 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of STRN3 protein | CTD | PMID:31675489 | Strn3 | Rat | bisphenol A | affects expression | ISO | STRN3 (Homo sapiens) | 6480464 | bisphenol A affects the expression of STRN3 mRNA | CTD | PMID:30903817 | Strn3 | Rat | bisphenol A | affects methylation | ISO | Strn3 (Mus musculus) | 6480464 | bisphenol A affects the methylation of STRN3 promoter | CTD | PMID:27334623 | Strn3 | Rat | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of STRN3 mRNA | CTD | PMID:33453195 | Strn3 | Rat | cadmium dichloride | decreases expression | ISO | STRN3 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of STRN3 mRNA | CTD | PMID:38382870 | Strn3 | Rat | caffeine | affects phosphorylation | ISO | STRN3 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of STRN3 protein | CTD | PMID:35688186 | Strn3 | Rat | copper(II) sulfate | increases expression | ISO | STRN3 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of STRN3 mRNA | CTD | PMID:19549813 | Strn3 | Rat | coumarin | decreases phosphorylation | ISO | STRN3 (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of STRN3 protein | CTD | PMID:35688186 | Strn3 | Rat | coumestrol | decreases expression | ISO | STRN3 (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of STRN3 mRNA | CTD | PMID:19167446 | Strn3 | Rat | coumestrol | multiple interactions | ISO | STRN3 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 more ... | CTD | PMID:19167446 | Strn3 | Rat | crocidolite asbestos | decreases expression | ISO | Strn3 (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of STRN3 mRNA | CTD | PMID:29279043 | Strn3 | Rat | cyclosporin A | increases expression | ISO | STRN3 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of STRN3 mRNA | CTD | PMID:25562108 | Strn3 | Rat | decabromodiphenyl ether | decreases expression | ISO | STRN3 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in decreased expression of STRN3 protein | CTD | PMID:31675489 | Strn3 | Rat | diarsenic trioxide | increases expression | ISO | STRN3 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of STRN3 mRNA | CTD | PMID:20458559 | Strn3 | Rat | dibenzo[a,l]pyrene | decreases expression | ISO | Strn3 (Mus musculus) | 6480464 | dibenzo(a and l)pyrene results in decreased expression of STRN3 mRNA | CTD | PMID:25908611 | Strn3 | Rat | Dibutyl phosphate | affects expression | ISO | STRN3 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of STRN3 mRNA | CTD | PMID:37042841 | Strn3 | Rat | dibutyl phthalate | increases expression | ISO | Strn3 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of STRN3 mRNA | CTD | PMID:21266533 | Strn3 | Rat | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of STRN3 mRNA | CTD | PMID:21266533 | Strn3 | Rat | dicrotophos | decreases expression | ISO | STRN3 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of STRN3 mRNA | CTD | PMID:28302478 | Strn3 | Rat | dimethylarsinous acid | affects expression | ISO | STRN3 (Homo sapiens) | 6480464 | dimethylarsinous acid affects the expression of STRN3 mRNA | CTD | PMID:20886546 | Strn3 | Rat | Enterolactone | multiple interactions | ISO | STRN3 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of STRN3 mRNA | CTD | PMID:19167446 | Strn3 | Rat | ethanol | affects splicing | ISO | Strn3 (Mus musculus) | 6480464 | Ethanol affects the splicing of STRN3 mRNA | CTD | PMID:30319688 | Strn3 | Rat | folic acid | multiple interactions | ISO | Strn3 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of STRN3 mRNA | CTD | PMID:22206623 | Strn3 | Rat | folic acid | decreases expression | ISO | Strn3 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of STRN3 mRNA | CTD | PMID:25629700 | Strn3 | Rat | FR900359 | increases phosphorylation | ISO | STRN3 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of STRN3 protein | CTD | PMID:37730182 | Strn3 | Rat | isoflurane | increases expression | ISO | Strn3 (Mus musculus) | 6480464 | Isoflurane results in increased expression of STRN3 protein | CTD | PMID:35249202 | Strn3 | Rat | ivermectin | decreases expression | ISO | STRN3 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of STRN3 protein | CTD | PMID:32959892 | Strn3 | Rat | leflunomide | increases expression | ISO | STRN3 (Homo sapiens) | 6480464 | leflunomide results in increased expression of STRN3 mRNA | CTD | PMID:28988120 | Strn3 | Rat | paracetamol | decreases expression | ISO | STRN3 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of STRN3 mRNA | CTD | PMID:21420995 | Strn3 | Rat | perfluorooctane-1-sulfonic acid | decreases expression | ISO | STRN3 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of STRN3 mRNA | CTD | PMID:27153767 | Strn3 | Rat | phenobarbital | affects expression | ISO | Strn3 (Mus musculus) | 6480464 | Phenobarbital affects the expression of STRN3 mRNA | CTD | PMID:23091169 | Strn3 | Rat | resveratrol | multiple interactions | ISO | STRN3 (Homo sapiens) | 6480464 | [Coumestrol co-treated with Resveratrol] results in decreased expression of STRN3 mRNA and [Plant Extracts co-treated with Resveratrol] results in increased expression of STRN3 mRNA | CTD | PMID:19167446 and PMID:23557933 | Strn3 | Rat | sodium arsenate | increases expression | ISO | Strn3 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of STRN3 mRNA | CTD | PMID:30953684 | Strn3 | Rat | sodium arsenite | affects expression | ISO | STRN3 (Homo sapiens) | 6480464 | sodium arsenite affects the expression of STRN3 mRNA | CTD | PMID:20886546 | Strn3 | Rat | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of STRN3 mRNA | CTD | PMID:19072884 | Strn3 | Rat | succimer | multiple interactions | ISO | Strn3 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of STRN3 mRNA | CTD | PMID:21641980 | Strn3 | Rat | testosterone enanthate | affects expression | ISO | STRN3 (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of STRN3 mRNA | CTD | PMID:17440010 | Strn3 | Rat | tetrachloromethane | increases expression | ISO | Strn3 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of STRN3 mRNA | CTD | PMID:31919559 | Strn3 | Rat | titanium dioxide | increases methylation | ISO | Strn3 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of STRN3 gene | CTD | PMID:35295148 | Strn3 | Rat | valproic acid | affects expression | ISO | Strn3 (Mus musculus) | 6480464 | Valproic Acid affects the expression of STRN3 mRNA | CTD | PMID:17292431 | Strn3 | Rat | valproic acid | decreases expression | ISO | STRN3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of STRN3 mRNA | CTD | PMID:23179753 and PMID:27188386 | |