Bin1 (bridging integrator 1) - Rat Genome Database

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Gene: Bin1 (bridging integrator 1) Rattus norvegicus
Analyze
Symbol: Bin1
Name: bridging integrator 1
RGD ID: 621786
Description: Enables GTPase binding activity. Involved in positive regulation of endocytosis and synaptic vesicle endocytosis. Located in several cellular components, including T-tubule; Z disc; and axon. Is active in glutamatergic synapse. Is extrinsic component of synaptic vesicle membrane. Human ortholog(s) of this gene implicated in breast carcinoma; centronuclear myopathy 2; and prostate adenocarcinoma. Orthologous to human BIN1 (bridging integrator 1); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Amph2; amphiphysin II; amphiphysin IIamph2; amphiphysin-like protein; MGC105358; myc box dependent interacting protein 1; myc box-dependent-interacting protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81824,282,840 - 24,341,461 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1824,283,801 - 24,341,458 (+)EnsemblGRCr8
mRatBN7.21824,009,731 - 24,067,267 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1824,009,653 - 24,067,263 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1824,137,876 - 24,195,311 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01824,896,662 - 24,953,442 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01824,232,875 - 24,290,326 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01825,163,575 - 25,222,139 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1825,163,561 - 25,222,135 (+)Ensemblrn6Rnor6.0
Rnor_5.01824,878,678 - 24,937,712 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41824,813,407 - 24,872,852 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1823,761,867 - 23,818,116 (+)NCBICelera
RGSC_v3.11824,840,052 - 24,899,497 (+)NCBI
Cytogenetic Map18p12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,6-dinitrotoluene  (EXP)
2-butoxyethanol  (ISO)
2-palmitoylglycerol  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
6-propyl-2-thiouracil  (EXP)
acetylsalicylic acid  (EXP)
aconitine  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
alachlor  (EXP)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
amphetamine  (EXP)
aristolochic acid A  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (EXP)
bortezomib  (ISO)
butyric acid  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
choline  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
diazinon  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dieldrin  (EXP)
diethylstilbestrol  (EXP)
doxorubicin  (ISO)
elemental selenium  (ISO)
ethanol  (ISO)
etoposide  (ISO)
fipronil  (EXP)
folic acid  (ISO)
FR900359  (ISO)
genistein  (EXP)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
ketoconazole  (EXP)
L-methionine  (ISO)
lithium atom  (ISO)
lithium hydride  (ISO)
methamphetamine  (EXP)
methoxychlor  (EXP)
nickel sulfate  (ISO)
nitrates  (ISO)
okadaic acid  (ISO)
ozone  (EXP)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
PCB138  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
selenium atom  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
temozolomide  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Amphiphysin II (SH3P9; BIN1), a member of the amphiphysin/Rvs family, is concentrated in the cortical cytomatrix of axon initial segments and nodes of ranvier in brain and around T tubules in skeletal muscle. Butler MH, etal., J Cell Biol. 1997 Jun 16;137(6):1355-67.
2. Immunohistochemical analysis of Bin1/Amphiphysin II in human tissues: diverse sites of nuclear expression and losses in prostate cancer. DuHadaway JB, etal., J Cell Biochem. 2003 Feb 15;88(3):635-42.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Losses of the tumor suppressor BIN1 in breast carcinoma are frequent and reflect deficits in programmed cell death capacity. Ge K, etal., Int J Cancer. 2000 Feb 1;85(3):376-83.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Clathrin interacts specifically with amphiphysin and is displaced by dynamin. McMahon HT, etal., FEBS Lett 1997 Aug 18;413(2):319-22.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Synaptojanin forms two separate complexes in the nerve terminal. Interactions with endophilin and amphiphysin. Micheva KD, etal., J Biol Chem. 1997 Oct 24;272(43):27239-45. doi: 10.1074/jbc.272.43.27239.
9. Mouse Genome Database (MGD) Mouse Genome Database (MGD)
10. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
11. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
12. Online Mendelian Inheritance in Man, OMIM (TM). Online Mendelian Inheritance in Man, OMIM (TM).
13. Crystal structure of the amphiphysin-2 SH3 domain and its role in the prevention of dynamin ring formation. Owen DJ, etal., EMBO J 1998 Sep 15;17(18):5273-85.
14. GOA pipeline RGD automated data pipeline
15. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. The NECAP PHear domain increases clathrin accessory protein binding potential. Ritter B, etal., EMBO J. 2007 Sep 19;26(18):4066-77. Epub 2007 Aug 30.
18. NECAP 1 regulates AP-2 interactions to control vesicle size, number, and cargo during clathrin-mediated endocytosis. Ritter B, etal., PLoS Biol. 2013 Oct;11(10):e1001670. doi: 10.1371/journal.pbio.1001670. Epub 2013 Oct 1.
19. Crystal structure of the alpha appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly. Traub LM, etal., Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):8907-12.
20. Amphiphysin heterodimers: potential role in clathrin-mediated endocytosis. Wigge P, etal., Mol Biol Cell 1997 Oct;8(10):2003-15.
Additional References at PubMed
PMID:8782822   PMID:9195986   PMID:9694653   PMID:10036185   PMID:10412034   PMID:11382783   PMID:11498538   PMID:12477932   PMID:15126636   PMID:15953416   PMID:16530520   PMID:18348166  
PMID:19004523   PMID:21700703   PMID:22871113   PMID:23399914   PMID:23917616   PMID:24534009   PMID:24755653   PMID:24836577   PMID:25051234   PMID:25332206   PMID:26506308   PMID:27179792  
PMID:27760323   PMID:28235806   PMID:28755476   PMID:29476059   PMID:31413325  


Genomics

Comparative Map Data
Bin1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81824,282,840 - 24,341,461 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1824,283,801 - 24,341,458 (+)EnsemblGRCr8
mRatBN7.21824,009,731 - 24,067,267 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1824,009,653 - 24,067,263 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1824,137,876 - 24,195,311 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01824,896,662 - 24,953,442 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01824,232,875 - 24,290,326 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01825,163,575 - 25,222,139 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1825,163,561 - 25,222,135 (+)Ensemblrn6Rnor6.0
Rnor_5.01824,878,678 - 24,937,712 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41824,813,407 - 24,872,852 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1823,761,867 - 23,818,116 (+)NCBICelera
RGSC_v3.11824,840,052 - 24,899,497 (+)NCBI
Cytogenetic Map18p12NCBI
BIN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382127,048,023 - 127,107,154 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2127,048,017 - 127,107,556 (-)Ensemblhg38GRCh38
GRCh372127,805,599 - 127,864,730 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362127,522,077 - 127,581,334 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342127,521,838 - 127,581,094NCBI
Celera2121,117,653 - 121,176,919 (-)NCBICelera
Cytogenetic Map2q14.3NCBI
HuRef2120,113,344 - 120,172,651 (-)NCBIHuRef
CHM1_12127,809,107 - 127,868,406 (-)NCBICHM1_1
T2T-CHM13v2.02127,482,408 - 127,541,545 (-)NCBIT2T-CHM13v2.0
Bin1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391832,509,671 - 32,568,793 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1832,510,283 - 32,568,790 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381832,376,618 - 32,435,740 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1832,377,230 - 32,435,737 (+)Ensemblmm10GRCm38
MGSCv371832,536,871 - 32,595,394 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361832,520,267 - 32,578,741 (+)NCBIMGSCv36mm8
Celera1832,859,551 - 32,918,381 (+)NCBICelera
Cytogenetic Map18B1NCBI
cM Map1818.01NCBI
Bin1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554593,399,611 - 3,422,621 (+)Ensembl
ChiLan1.0NW_0049554593,376,149 - 3,423,157 (+)NCBIChiLan1.0ChiLan1.0
BIN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21348,536,717 - 48,596,250 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B48,551,951 - 48,611,232 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B33,168,767 - 33,228,075 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B127,716,543 - 127,775,378 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B127,716,550 - 127,775,378 (-)EnsemblpanPan2panpan1.1
BIN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11923,503,934 - 23,534,407 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1923,375,363 - 23,534,303 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1923,722,237 - 23,775,092 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01924,808,041 - 24,860,795 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1924,807,994 - 24,860,791 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11923,511,306 - 23,564,134 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01923,700,703 - 23,753,544 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01924,831,980 - 24,884,833 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Bin1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530397,432,383 - 97,489,370 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646944,127,970 - 44,185,246 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493646944,128,308 - 44,185,739 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BIN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1525,328,674 - 25,383,652 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11525,328,679 - 25,379,675 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21529,008,956 - 29,057,185 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BIN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1103,112,605 - 3,173,522 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl103,113,868 - 3,173,620 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606119,562,554 - 19,622,802 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bin1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473213,544,507 - 13,592,795 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473213,543,975 - 13,592,942 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Bin1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11511,805,337 - 11,862,135 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Bin1
290 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:504
Count of miRNA genes:179
Interacting mature miRNAs:201
Transcripts:ENSRNOT00000017573, ENSRNOT00000042287, ENSRNOT00000049898, ENSRNOT00000051370
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2301410Bp317Blood pressure QTL 3170.004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181221923726822399Rat
2301409Cm70Cardiac mass QTL 700.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)18706572852065728Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)182201556261600538Rat
1331735Rf44Renal function QTL 442.981urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)181564228031610627Rat
61382Bp46Blood pressure QTL 4618.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181221668431644508Rat
12904716Am21Aortic mass QTL 210.005aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)18706572852065728Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182349405785487725Rat
8552968Pigfal19Plasma insulin-like growth factor 1 level QTL 1911.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)18126032889Rat
12904714Cm131Cardiac mass QTL 1310.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)18706572852065728Rat
12904715Cm132Cardiac mass QTL 1320.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)18706572852065728Rat
1331781Scl28Serum cholesterol level QTL 283.995blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)18125071266Rat
6903345Bp349Blood pressure QTL 3493.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18391722648917226Rat
2313082Bss85Bone structure and strength QTL 850.80.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)181522610142690662Rat
6903347Bp350Blood pressure QTL 3504.4arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18131610627Rat
2312568Glom21Glomerulus QTL 2120.005kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)18546045542690191Rat
6903349Bp351Blood pressure QTL 3513.5arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18391722648917226Rat
6903351Bp352Blood pressure QTL 3523.3arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18391722648917226Rat
1331766Bp236Blood pressure QTL 2363.022arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18131610627Rat
631264Scl22Serum cholesterol level QTL 226.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)181221668431644508Rat
1331775Bp235Blood pressure QTL 2353.201arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181564228031610627Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18144930869Rat
12904680Bw189Body weight QTL 1890.019body mass (VT:0001259)body weight (CMO:0000012)181221923726822399Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181955353285493247Rat
2293708Bss46Bone structure and strength QTL 468.80.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)181206648257066482Rat
1641910Colcr3Colorectal carcinoma resistance QTL 35.020.000007intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)18125022372Rat
12904693Am20Aortic mass QTL 200.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)181221923726822399Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181206648285493247Rat
12904695Kidm73Kidney mass QTL 730.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)181221923726822399Rat
2312598Bp340Blood pressure QTL 3400.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18381190230809809Rat
12904689Cm128Cardiac mass QTL 1280.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)181221923726822399Rat
12904690Cm129Cardiac mass QTL 1290.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)181221923726822399Rat
2300180Bmd67Bone mineral density QTL 674.80.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)18134566578Rat
12904691Cm130Cardiac mass QTL 1300.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)181221923726822399Rat
9590248Scort10Serum corticosterone level QTL 1019.710.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)18126032889Rat
2299160Iddm35Insulin dependent diabetes mellitus QTL 352.79blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)18448264849482648Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18154490981Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181206648285493247Rat
11565454Kidm59Kidney mass QTL 590.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)18706572852065728Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181564228086134022Rat
2293661Bss50Bone structure and strength QTL 504.640.0003lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)18134566578Rat
61375Bp41Blood pressure QTL 412.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)18430735449307354Rat

Markers in Region
U86405  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21824,066,791 - 24,066,931 (+)MAPPERmRatBN7.2
Rnor_6.01825,221,664 - 25,221,803NCBIRnor6.0
Rnor_5.01824,937,237 - 24,937,376UniSTSRnor5.0
RGSC_v3.41824,872,380 - 24,872,519UniSTSRGSC3.4
Celera1823,817,644 - 23,817,783UniSTS
Cytogenetic Map18p12UniSTS
PMC156129P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21824,044,651 - 24,045,610 (+)MAPPERmRatBN7.2
Rnor_6.01825,198,511 - 25,199,469NCBIRnor6.0
Rnor_5.01824,913,661 - 24,914,619UniSTSRnor5.0
RGSC_v3.41824,848,568 - 24,849,526UniSTSRGSC3.4
Celera1823,795,110 - 23,796,068UniSTS
Cytogenetic Map18p12UniSTS
RH141034  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21824,067,010 - 24,067,196 (+)MAPPERmRatBN7.2
Rnor_6.01825,221,883 - 25,222,068NCBIRnor6.0
Rnor_5.01824,937,456 - 24,937,641UniSTSRnor5.0
RGSC_v3.41824,872,599 - 24,872,784UniSTSRGSC3.4
Celera1823,817,863 - 23,818,048UniSTS
RH 3.4 Map18301.1UniSTS
Cytogenetic Map18p12UniSTS
RH141074  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21824,059,836 - 24,060,025 (+)MAPPERmRatBN7.2
Rnor_6.01825,214,717 - 25,214,905NCBIRnor6.0
Rnor_5.01824,930,290 - 24,930,478UniSTSRnor5.0
RGSC_v3.41824,865,433 - 24,865,621UniSTSRGSC3.4
Celera1823,810,698 - 23,810,886UniSTS
RH 3.4 Map18301.8UniSTS
Cytogenetic Map18p12UniSTS
PMC156129P2  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81824,318,029 - 24,318,302 (+)Marker Load Pipeline
mRatBN7.21824,043,830 - 24,044,103 (+)MAPPERmRatBN7.2
Rnor_6.01825,197,690 - 25,197,962NCBIRnor6.0
Rnor_5.01824,912,840 - 24,913,112UniSTSRnor5.0
RGSC_v3.41824,847,747 - 24,848,019UniSTSRGSC3.4
Celera1823,794,289 - 23,794,561UniSTS
Cytogenetic Map18p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_053959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039096550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039096554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039096555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039096556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC089109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y13380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000017573   ⟹   ENSRNOP00000017573
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1824,283,951 - 24,341,458 (+)Ensembl
mRatBN7.2 Ensembl1824,009,804 - 24,067,263 (+)Ensembl
Rnor_6.0 Ensembl1825,163,648 - 25,222,135 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000042287   ⟹   ENSRNOP00000042320
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1824,283,951 - 24,341,458 (+)Ensembl
mRatBN7.2 Ensembl1824,009,804 - 24,067,263 (+)Ensembl
Rnor_6.0 Ensembl1825,163,561 - 25,222,135 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000049898   ⟹   ENSRNOP00000040191
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1824,284,013 - 24,341,448 (+)Ensembl
mRatBN7.2 Ensembl1824,009,797 - 24,067,256 (+)Ensembl
Rnor_6.0 Ensembl1825,163,604 - 25,222,132 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096264   ⟹   ENSRNOP00000087136
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1824,283,801 - 24,341,454 (+)Ensembl
mRatBN7.2 Ensembl1824,009,653 - 24,067,257 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105880   ⟹   ENSRNOP00000077086
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1824,283,956 - 24,341,448 (+)Ensembl
mRatBN7.2 Ensembl1824,009,804 - 24,067,263 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000111732   ⟹   ENSRNOP00000097221
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1824,303,855 - 24,341,456 (+)Ensembl
mRatBN7.2 Ensembl1824,029,658 - 24,067,260 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119810   ⟹   ENSRNOP00000094103
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1824,283,964 - 24,341,454 (+)Ensembl
mRatBN7.2 Ensembl1824,009,653 - 24,067,257 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000127521   ⟹   ENSRNOP00000101123
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1824,283,801 - 24,341,454 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000136210   ⟹   ENSRNOP00000100862
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1824,283,856 - 24,341,454 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000149219   ⟹   ENSRNOP00000111965
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1824,284,002 - 24,341,454 (+)Ensembl
RefSeq Acc Id: NM_053959   ⟹   NP_446411
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81824,283,951 - 24,341,458 (+)NCBI
mRatBN7.21824,009,748 - 24,067,267 (+)NCBI
Rnor_6.01825,163,648 - 25,222,136 (+)NCBI
Rnor_5.01824,878,678 - 24,937,712 (+)NCBI
RGSC_v3.41824,813,407 - 24,872,852 (+)RGD
Celera1823,761,867 - 23,818,116 (+)RGD
Sequence:
RefSeq Acc Id: XM_006254496   ⟹   XP_006254558
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81824,283,861 - 24,341,461 (+)NCBI
mRatBN7.21824,009,731 - 24,067,267 (+)NCBI
Rnor_6.01825,163,575 - 25,222,139 (+)NCBI
Rnor_5.01824,878,678 - 24,937,712 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006254497   ⟹   XP_006254559
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81824,283,861 - 24,341,461 (+)NCBI
mRatBN7.21824,009,731 - 24,067,267 (+)NCBI
Rnor_6.01825,163,575 - 25,222,139 (+)NCBI
Rnor_5.01824,878,678 - 24,937,712 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006254499   ⟹   XP_006254561
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81824,283,861 - 24,341,461 (+)NCBI
mRatBN7.21824,009,731 - 24,067,267 (+)NCBI
Rnor_6.01825,163,575 - 25,222,139 (+)NCBI
Rnor_5.01824,878,678 - 24,937,712 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006254500   ⟹   XP_006254562
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81824,283,861 - 24,341,461 (+)NCBI
mRatBN7.21824,009,731 - 24,067,267 (+)NCBI
Rnor_6.01825,163,575 - 25,222,139 (+)NCBI
Rnor_5.01824,878,678 - 24,937,712 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006254501   ⟹   XP_006254563
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81824,283,861 - 24,341,461 (+)NCBI
mRatBN7.21824,009,731 - 24,067,267 (+)NCBI
Rnor_6.01825,163,575 - 25,222,139 (+)NCBI
Rnor_5.01824,878,678 - 24,937,712 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006254502   ⟹   XP_006254564
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81824,283,861 - 24,341,461 (+)NCBI
mRatBN7.21824,009,731 - 24,067,267 (+)NCBI
Rnor_6.01825,163,575 - 25,222,139 (+)NCBI
Rnor_5.01824,878,678 - 24,937,712 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006254503   ⟹   XP_006254565
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81824,283,861 - 24,341,461 (+)NCBI
mRatBN7.21824,009,731 - 24,067,267 (+)NCBI
Rnor_6.01825,163,575 - 25,222,139 (+)NCBI
Rnor_5.01824,878,678 - 24,937,712 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006254504   ⟹   XP_006254566
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81824,283,811 - 24,341,461 (+)NCBI
mRatBN7.21824,009,731 - 24,067,267 (+)NCBI
Rnor_6.01825,163,575 - 25,222,139 (+)NCBI
Rnor_5.01824,878,678 - 24,937,712 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006254505   ⟹   XP_006254567
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81824,282,840 - 24,341,461 (+)NCBI
mRatBN7.21824,009,731 - 24,067,267 (+)NCBI
Rnor_6.01825,163,575 - 25,222,139 (+)NCBI
Rnor_5.01824,878,678 - 24,937,712 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008772014   ⟹   XP_008770236
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81824,283,861 - 24,341,461 (+)NCBI
mRatBN7.21824,009,731 - 24,067,267 (+)NCBI
Rnor_6.01825,163,575 - 25,222,139 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600830   ⟹   XP_017456319
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81824,283,861 - 24,341,461 (+)NCBI
mRatBN7.21824,009,731 - 24,067,267 (+)NCBI
Rnor_6.01825,163,575 - 25,222,139 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600831   ⟹   XP_017456320
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81824,283,861 - 24,341,461 (+)NCBI
mRatBN7.21824,009,731 - 24,067,267 (+)NCBI
Rnor_6.01825,163,575 - 25,222,139 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600832   ⟹   XP_017456321
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81824,282,840 - 24,341,461 (+)NCBI
mRatBN7.21824,009,731 - 24,067,267 (+)NCBI
Rnor_6.01825,163,575 - 25,222,139 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039096550   ⟹   XP_038952478
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81824,283,861 - 24,341,461 (+)NCBI
mRatBN7.21824,009,731 - 24,067,267 (+)NCBI
RefSeq Acc Id: XM_039096554   ⟹   XP_038952482
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81824,283,861 - 24,341,461 (+)NCBI
mRatBN7.21824,009,731 - 24,067,267 (+)NCBI
RefSeq Acc Id: XM_039096555   ⟹   XP_038952483
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81824,283,861 - 24,341,461 (+)NCBI
mRatBN7.21824,009,731 - 24,067,267 (+)NCBI
RefSeq Acc Id: XM_039096556   ⟹   XP_038952484
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81824,283,861 - 24,341,461 (+)NCBI
mRatBN7.21824,009,731 - 24,067,267 (+)NCBI
RefSeq Acc Id: XM_063277071   ⟹   XP_063133141
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81824,283,861 - 24,341,461 (+)NCBI
RefSeq Acc Id: XM_063277073   ⟹   XP_063133143
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81824,283,861 - 24,341,461 (+)NCBI
RefSeq Acc Id: XM_063277074   ⟹   XP_063133144
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81824,283,861 - 24,341,461 (+)NCBI
RefSeq Acc Id: XM_063277075   ⟹   XP_063133145
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81824,303,863 - 24,341,461 (+)NCBI
RefSeq Acc Id: XM_063277077   ⟹   XP_063133147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81824,303,864 - 24,341,461 (+)NCBI
RefSeq Acc Id: XM_063277078   ⟹   XP_063133148
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81824,303,868 - 24,341,461 (+)NCBI
Protein Sequences
Protein RefSeqs NP_446411 (Get FASTA)   NCBI Sequence Viewer  
  XP_006254558 (Get FASTA)   NCBI Sequence Viewer  
  XP_006254559 (Get FASTA)   NCBI Sequence Viewer  
  XP_006254561 (Get FASTA)   NCBI Sequence Viewer  
  XP_006254562 (Get FASTA)   NCBI Sequence Viewer  
  XP_006254563 (Get FASTA)   NCBI Sequence Viewer  
  XP_006254564 (Get FASTA)   NCBI Sequence Viewer  
  XP_006254565 (Get FASTA)   NCBI Sequence Viewer  
  XP_006254566 (Get FASTA)   NCBI Sequence Viewer  
  XP_006254567 (Get FASTA)   NCBI Sequence Viewer  
  XP_008770236 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456319 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456320 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456321 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952478 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952482 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952483 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952484 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133141 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133143 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133144 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133145 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133147 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133148 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH89109 (Get FASTA)   NCBI Sequence Viewer  
  CAA73807 (Get FASTA)   NCBI Sequence Viewer  
  EDL76189 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000017573
  ENSRNOP00000017573.7
  ENSRNOP00000040191
  ENSRNOP00000042320
  ENSRNOP00000077086
  ENSRNOP00000087136
  ENSRNOP00000094103
  ENSRNOP00000097221
  ENSRNOP00000100862
  ENSRNOP00000101123
GenBank Protein O08839 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_446411   ⟸   NM_053959
- UniProtKB: O08839 (UniProtKB/Swiss-Prot),   A6J2Q7 (UniProtKB/TrEMBL),   F1LMX1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254567   ⟸   XM_006254505
- Peptide Label: isoform X21
- UniProtKB: Q5HZA7 (UniProtKB/TrEMBL),   D4ACI3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254558   ⟸   XM_006254496
- Peptide Label: isoform X1
- UniProtKB: F1LMX1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254561   ⟸   XM_006254499
- Peptide Label: isoform X4
- UniProtKB: F1LMX1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254562   ⟸   XM_006254500
- Peptide Label: isoform X7
- UniProtKB: F1LMX1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254564   ⟸   XM_006254502
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_006254563   ⟸   XM_006254501
- Peptide Label: isoform X8
- UniProtKB: D4A4P1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254559   ⟸   XM_006254497
- Peptide Label: isoform X2
- UniProtKB: D4A4P1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254565   ⟸   XM_006254503
- Peptide Label: isoform X11
- UniProtKB: A0A8I6A3N4 (UniProtKB/TrEMBL),   D4A4P1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254566   ⟸   XM_006254504
- Peptide Label: isoform X19
- UniProtKB: A0A8J8YMC5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770236   ⟸   XM_008772014
- Peptide Label: isoform X17
- Sequence:
RefSeq Acc Id: XP_017456319   ⟸   XM_017600830
- Peptide Label: isoform X6
- UniProtKB: F1LMX1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456320   ⟸   XM_017600831
- Peptide Label: isoform X13
- Sequence:
RefSeq Acc Id: XP_017456321   ⟸   XM_017600832
- Peptide Label: isoform X20
- Sequence:
Ensembl Acc Id: ENSRNOP00000017573   ⟸   ENSRNOT00000017573
Ensembl Acc Id: ENSRNOP00000042320   ⟸   ENSRNOT00000042287
Ensembl Acc Id: ENSRNOP00000040191   ⟸   ENSRNOT00000049898
RefSeq Acc Id: XP_038952482   ⟸   XM_039096554
- Peptide Label: isoform X14
RefSeq Acc Id: XP_038952478   ⟸   XM_039096550
- Peptide Label: isoform X3
- UniProtKB: F1LMX1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038952484   ⟸   XM_039096556
- Peptide Label: isoform X18
- UniProtKB: A0A8I5Y9B3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038952483   ⟸   XM_039096555
- Peptide Label: isoform X15
- UniProtKB: A0A8I6ANM7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000087136   ⟸   ENSRNOT00000096264
Ensembl Acc Id: ENSRNOP00000094103   ⟸   ENSRNOT00000119810
Ensembl Acc Id: ENSRNOP00000077086   ⟸   ENSRNOT00000105880
Ensembl Acc Id: ENSRNOP00000097221   ⟸   ENSRNOT00000111732
RefSeq Acc Id: XP_063133143   ⟸   XM_063277073
- Peptide Label: isoform X9
- UniProtKB: F1LMX1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133144   ⟸   XM_063277074
- Peptide Label: isoform X12
- UniProtKB: D4A4P1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133141   ⟸   XM_063277071
- Peptide Label: isoform X5
- UniProtKB: D4A4P1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133145   ⟸   XM_063277075
- Peptide Label: isoform X16
RefSeq Acc Id: XP_063133147   ⟸   XM_063277077
- Peptide Label: isoform X22
RefSeq Acc Id: XP_063133148   ⟸   XM_063277078
- Peptide Label: isoform X23
- UniProtKB: A0A8I6AU27 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000101123   ⟸   ENSRNOT00000127521
Ensembl Acc Id: ENSRNOP00000100862   ⟸   ENSRNOT00000136210
Ensembl Acc Id: ENSRNOP00000111965   ⟸   ENSRNOT00000149219
Protein Domains
BAR   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O08839-F1-model_v2 AlphaFold O08839 1-588 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700688
Promoter ID:EPDNEW_R11209
Type:initiation region
Name:Bin1_1
Description:bridging integrator 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01825,163,592 - 25,163,652EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621786 AgrOrtholog
BIND 130568
  130569
  130570
BioCyc Gene G2FUF-8035 BioCyc
Ensembl Genes ENSRNOG00000012852 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000017573 ENTREZGENE
  ENSRNOT00000017573.8 UniProtKB/Swiss-Prot
  ENSRNOT00000042287 ENTREZGENE
  ENSRNOT00000049898 ENTREZGENE
  ENSRNOT00000096264 ENTREZGENE
  ENSRNOT00000105880 ENTREZGENE
  ENSRNOT00000111732 ENTREZGENE
  ENSRNOT00000119810 ENTREZGENE
  ENSRNOT00000127521 ENTREZGENE
  ENSRNOT00000136210 ENTREZGENE
Gene3D-CATH 1.20.1270.60 UniProtKB/Swiss-Prot
  SH3 Domains UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7311357 IMAGE-MGC_LOAD
InterPro AH/BAR_dom_sf UniProtKB/Swiss-Prot
  Amphiphysin UniProtKB/Swiss-Prot
  Amphiphysin-2_SH3 UniProtKB/Swiss-Prot
  Amphiphysin_2 UniProtKB/Swiss-Prot
  BAR_dom UniProtKB/Swiss-Prot
  SH3-like_dom_sf UniProtKB/Swiss-Prot
  SH3_domain UniProtKB/Swiss-Prot
KEGG Report rno:117028 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105358 IMAGE-MGC_LOAD
NCBI Gene 117028 ENTREZGENE
PANTHER AMPHIPHYSIN UniProtKB/Swiss-Prot
  PTHR46514:SF4 UniProtKB/Swiss-Prot
Pfam BAR UniProtKB/Swiss-Prot
  SH3_9 UniProtKB/Swiss-Prot
PhenoGen Bin1 PhenoGen
PRINTS AMPHIPHYSIN UniProtKB/Swiss-Prot
  AMPHIPHYSIN2 UniProtKB/Swiss-Prot
  SH3DOMAIN UniProtKB/Swiss-Prot
PROSITE BAR UniProtKB/Swiss-Prot
  SH3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000012852 RatGTEx
SMART BAR UniProtKB/Swiss-Prot
  SH3 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF103657 UniProtKB/Swiss-Prot
  SSF50044 UniProtKB/Swiss-Prot
UniProt A0A8I5Y9B3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A3N4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ANM7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AU27 ENTREZGENE, UniProtKB/TrEMBL
  A0A8J8YMC5 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L9U3_RAT UniProtKB/TrEMBL
  A0ABK0LG93_RAT UniProtKB/TrEMBL
  A0ABK0LLZ1_RAT UniProtKB/TrEMBL
  A6J2Q7 ENTREZGENE, UniProtKB/TrEMBL
  BIN1_RAT UniProtKB/Swiss-Prot
  D4A4P1 ENTREZGENE, UniProtKB/TrEMBL
  D4ACI3 ENTREZGENE
  F1LMX1 ENTREZGENE, UniProtKB/TrEMBL
  O08839 ENTREZGENE
  Q5HZA7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-01-20 Bin1  bridging integrator 1    myc box dependent interacting protein 1  Name updated 1299863 APPROVED
2002-08-07 Bin1  myc box dependent interacting protein 1      Symbol and Name status set to provisional 70820 PROVISIONAL