Il1rl2 (interleukin 1 receptor-like 2) - Rat Genome Database

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Gene: Il1rl2 (interleukin 1 receptor-like 2) Rattus norvegicus
Analyze
Symbol: Il1rl2
Name: interleukin 1 receptor-like 2
RGD ID: 621782
Description: Predicted to enable NAD+ nucleosidase activity, cyclic ADP-ribose generating and interleukin-1 receptor activity. Predicted to be involved in cell surface receptor signaling pathway and regulation of inflammatory response. Predicted to act upstream of or within several processes, including cytokine-mediated signaling pathway; positive regulation of T cell differentiation; and positive regulation of interleukin-6 production. Predicted to be located in membrane. Predicted to be active in cell surface and plasma membrane. Orthologous to human IL1RL2 (interleukin 1 receptor like 2); INTERACTS WITH alpha-Zearalanol; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: IL-1Rrp2; IL-36 receptor; IL1R-rp2; interleukin-1 receptor-like 2; interleukin-1 receptor-related protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Il1rl2tm1(Myh6-cre)Mhzh
Genetic Models: SD-Il1rl2tm1(Myh6-cre)Mhzh
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8950,087,271 - 50,134,225 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl950,083,903 - 50,204,607 (+)EnsemblGRCr8
mRatBN7.2942,591,658 - 42,639,351 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl942,591,934 - 42,636,667 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx951,094,273 - 51,139,209 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0956,216,970 - 56,261,896 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0954,492,602 - 54,537,352 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0947,044,870 - 47,093,679 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl947,047,832 - 47,095,831 (+)Ensemblrn6Rnor6.0
Rnor_5.0946,733,619 - 46,778,352 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4939,492,187 - 39,537,792 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera940,337,394 - 40,381,411 (+)NCBICelera
RGSC_v3.1939,493,600 - 39,539,206 (+)NCBI
Cytogenetic Map9q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Cloning of a cDNA encoding a novel interleukin-1 receptor related protein (IL 1R-rp2). Lovenberg TW, etal., J Neuroimmunol 1996 Nov;70(2):113-22.
3. Deficiency of Interleukin-36 Receptor Protected Cardiomyocytes from Ischemia-Reperfusion Injury in Cardiopulmonary Bypass. Luo C, etal., Med Sci Monit. 2020 Feb 12;26:e918933. doi: 10.12659/MSM.918933.
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:21860022   PMID:22968459   PMID:23064362  


Genomics

Comparative Map Data
Il1rl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8950,087,271 - 50,134,225 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl950,083,903 - 50,204,607 (+)EnsemblGRCr8
mRatBN7.2942,591,658 - 42,639,351 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl942,591,934 - 42,636,667 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx951,094,273 - 51,139,209 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0956,216,970 - 56,261,896 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0954,492,602 - 54,537,352 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0947,044,870 - 47,093,679 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl947,047,832 - 47,095,831 (+)Ensemblrn6Rnor6.0
Rnor_5.0946,733,619 - 46,778,352 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4939,492,187 - 39,537,792 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera940,337,394 - 40,381,411 (+)NCBICelera
RGSC_v3.1939,493,600 - 39,539,206 (+)NCBI
Cytogenetic Map9q22NCBI
IL1RL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382102,186,973 - 102,243,086 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2102,186,980 - 102,240,002 (+)Ensemblhg38GRCh38
GRCh372102,803,433 - 102,856,462 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362102,169,865 - 102,222,243 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342102,261,950 - 102,314,329NCBI
Celera297,004,649 - 97,057,020 (+)NCBICelera
Cytogenetic Map2q12.1NCBI
HuRef296,567,290 - 96,619,802 (+)NCBIHuRef
CHM1_12102,807,775 - 102,860,073 (+)NCBICHM1_1
T2T-CHM13v2.02102,645,259 - 102,701,349 (+)NCBIT2T-CHM13v2.0
Il1rl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39140,363,697 - 40,406,722 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl140,363,770 - 40,406,722 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38140,324,589 - 40,367,555 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl140,324,610 - 40,367,562 (+)Ensemblmm10GRCm38
MGSCv37140,381,472 - 40,422,316 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36140,269,173 - 40,310,017 (+)NCBIMGSCv36mm8
Celera140,135,784 - 40,176,671 (+)NCBICelera
Cytogenetic Map1BNCBI
cM Map118.96NCBI
Il1rl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554707,704,134 - 7,742,064 (+)Ensembl
ChiLan1.0NW_0049554707,703,369 - 7,742,058 (+)NCBIChiLan1.0ChiLan1.0
IL1RL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21225,995,088 - 26,049,489 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A25,997,849 - 26,051,650 (-)NCBINHGRI_mPanPan1
PanPan1.12A103,237,107 - 103,289,427 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A103,237,996 - 103,289,414 (+)EnsemblpanPan2panpan1.1
IL1RL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11040,776,670 - 40,817,263 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1040,778,590 - 40,816,044 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1040,698,936 - 40,742,868 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01041,639,600 - 41,683,546 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1041,645,070 - 41,682,534 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11041,353,871 - 41,397,328 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01041,635,603 - 41,679,766 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01041,827,554 - 41,871,492 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Il1rl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629290,201,299 - 90,240,726 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936713893,769 - 930,889 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936713893,020 - 932,406 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL1RL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl351,966,691 - 52,011,479 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1351,978,857 - 52,011,607 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2354,382,183 - 54,396,574 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IL1RL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1145,862,140 - 5,912,789 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl145,863,727 - 5,915,370 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041173,542,157 - 173,595,405 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Il1rl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247496,749,007 - 6,779,753 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247496,747,131 - 6,781,908 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Il1rl2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v14116,568,595 - 116,608,993 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Il1rl2
343 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:249
Count of miRNA genes:186
Interacting mature miRNAs:209
Transcripts:ENSRNOT00000019880
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)9671488884474983Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9534647950346479Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)94002992585029925Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9875049253750492Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)93125043268875676Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)94445825699506504Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)92956766474567664Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)94445825685262605Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92956766483835942Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)94172029586720295Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9621499551214995Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9875049253750492Rat
7207805Bmd88Bone mineral density QTL 884femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)93125043265651574Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9534647950416711Rat
1581517Bp284Blood pressure QTL 284arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)93922018684220186Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)948718864108376862Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)94002992585029925Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9621499551214995Rat
1598823Memor16Memory QTL 161.9exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)93145606157460683Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)93496059079960590Rat


Genetic Models
This gene Il1rl2 is modified in the following models/strains:
SD-Il1rl2tm1(Myh6-cre)Mhzh    


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
14 7 62 133 80 85 54 80 54 6 313 167 9 111 73 92 31 8 8

Sequence


Ensembl Acc Id: ENSRNOT00000019880   ⟹   ENSRNOP00000019880
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl950,087,552 - 50,204,607 (+)Ensembl
mRatBN7.2 Ensembl942,591,934 - 42,636,667 (+)Ensembl
Rnor_6.0 Ensembl947,047,832 - 47,095,831 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000135930   ⟹   ENSRNOP00000110127
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl950,087,552 - 50,139,436 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000137233   ⟹   ENSRNOP00000098736
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl950,083,903 - 50,134,216 (+)Ensembl
RefSeq Acc Id: NM_133575   ⟹   NP_598259
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8950,087,552 - 50,132,302 (+)NCBI
mRatBN7.2942,591,934 - 42,636,667 (+)NCBI
Rnor_6.0947,048,915 - 47,093,679 (+)NCBI
Rnor_5.0946,733,619 - 46,778,352 (+)NCBI
RGSC_v3.4939,492,187 - 39,537,792 (+)RGD
Celera940,337,394 - 40,381,411 (+)RGD
Sequence:
RefSeq Acc Id: XM_017596259   ⟹   XP_017451748
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8950,087,271 - 50,134,225 (+)NCBI
mRatBN7.2942,591,658 - 42,639,351 (+)NCBI
Rnor_6.0947,048,447 - 47,093,600 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_598259 (Get FASTA)   NCBI Sequence Viewer  
  XP_017451748 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB53238 (Get FASTA)   NCBI Sequence Viewer  
  EDL99176 (Get FASTA)   NCBI Sequence Viewer  
  EDL99177 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000098736
  ENSRNOP00000110127
GenBank Protein Q62929 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_598259   ⟸   NM_133575
- Peptide Label: precursor
- UniProtKB: Q62929 (UniProtKB/Swiss-Prot),   G3V7W4 (UniProtKB/TrEMBL),   A6INN3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451748   ⟸   XM_017596259
- Peptide Label: isoform X1
- UniProtKB: Q62929 (UniProtKB/Swiss-Prot),   G3V7W4 (UniProtKB/TrEMBL),   A6INN3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000019880   ⟸   ENSRNOT00000019880
Ensembl Acc Id: ENSRNOP00000110127   ⟸   ENSRNOT00000135930
Ensembl Acc Id: ENSRNOP00000098736   ⟸   ENSRNOT00000137233
Protein Domains
Ig-like   Ig-like C2-type   TIR

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62929-F1-model_v2 AlphaFold Q62929 1-561 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621782 AgrOrtholog
BioCyc Gene G2FUF-27724 BioCyc
Ensembl Genes ENSRNOG00000014683 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000135930 ENTREZGENE
  ENSRNOT00000137233 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
  3.40.50.10140 UniProtKB/Swiss-Prot
InterPro Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  Ig_sub2 UniProtKB/Swiss-Prot
  IL-1_rcpt_fam UniProtKB/Swiss-Prot
  IL-1_rcpt_I/II-typ UniProtKB/Swiss-Prot
  TIR_dom UniProtKB/Swiss-Prot
  Toll_tir_struct_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:171106 UniProtKB/Swiss-Prot
NCBI Gene 171106 ENTREZGENE
PANTHER INTERLEUKIN-1 RECEPTOR-LIKE 2 UniProtKB/Swiss-Prot
  PTHR11890 UniProtKB/Swiss-Prot
Pfam Ig_2 UniProtKB/Swiss-Prot
  TIR UniProtKB/Swiss-Prot
PhenoGen Il1rl2 PhenoGen
PRINTS INTRLKN1R12F UniProtKB/Swiss-Prot
  INTRLKN1R1F UniProtKB/Swiss-Prot
PROSITE IG_LIKE UniProtKB/Swiss-Prot
  TIR UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000014683 RatGTEx
SMART IGc2 UniProtKB/Swiss-Prot
  SM00409 UniProtKB/Swiss-Prot
  TIR UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
  SSF52200 UniProtKB/Swiss-Prot
UniProt A0ABK0LF45_RAT UniProtKB/TrEMBL
  A0ABK0M771_RAT UniProtKB/TrEMBL
  A6INN3 ENTREZGENE, UniProtKB/TrEMBL
  G3V7W4 ENTREZGENE, UniProtKB/TrEMBL
  ILRL2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Il1rl2  interleukin 1 receptor-like 2      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Il1rl2  interleukin 1 receptor-like 2      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in lung and epididymis with lower levels of expression detected in the testis and cerebral cortex 729063
gene_function did not bind either [125I]-recombinant human IL 1 alpha or [125I]-recombinant human IL 1 beta with high affinity 729063