Fbxo2 (F-box protein 2) - Rat Genome Database

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Gene: Fbxo2 (F-box protein 2) Rattus norvegicus
Analyze
Symbol: Fbxo2
Name: F-box protein 2
RGD ID: 621751
Description: Predicted to enable amyloid-beta binding activity; carbohydrate binding activity; and denatured protein binding activity. Predicted to contribute to ubiquitin protein ligase activity. Involved in negative regulation of cell population proliferation. Is active in glutamatergic synapse. Is extrinsic component of postsynaptic membrane. Orthologous to human FBXO2 (F-box protein 2); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: F-box only protein 2; neural F box protein NFB42
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85163,876,079 - 163,881,508 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5163,875,757 - 163,881,508 (+)EnsemblGRCr8
mRatBN7.25158,592,926 - 158,598,355 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5158,592,925 - 158,598,355 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5161,309,703 - 161,315,130 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05163,131,494 - 163,136,941 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05163,087,839 - 163,093,286 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05164,972,483 - 164,977,912 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5164,972,480 - 164,977,916 (+)Ensemblrn6Rnor6.0
Rnor_5.05168,630,521 - 168,635,950 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45165,239,080 - 165,244,509 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5156,871,142 - 156,876,571 (+)NCBICelera
RGSC_v3.15165,249,267 - 165,254,697 (+)NCBI
Cytogenetic Map5q36NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methoxyethanol  (EXP)
6-propyl-2-thiouracil  (EXP)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
C60 fullerene  (EXP)
cadmium dichloride  (ISO)
calcitriol  (ISO)
camptothecin  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
cytarabine  (ISO)
DDE  (ISO)
deoxynivalenol  (ISO)
dextran sulfate  (ISO)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
dieldrin  (EXP)
dorsomorphin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
ethanol  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
gentamycin  (EXP)
GSK-J4  (ISO)
isobutanol  (ISO)
isoniazide  (ISO)
ivermectin  (ISO)
ketamine  (EXP)
lead(0)  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
naled  (ISO)
nickel dichloride  (EXP)
niclosamide  (ISO)
Nivalenol  (ISO)
Nutlin-3  (ISO)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
perfluorooctanoic acid  (ISO)
propanal  (ISO)
quercetin  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
T-2 toxin  (EXP)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. A novel F box protein, NFB42, is highly enriched in neurons and induces growth arrest. Erhardt JA, etal., J Biol Chem 1998 Dec 25;273(52):35222-7.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Activity-dependent NMDA receptor degradation mediated by retrotranslocation and ubiquitination. Kato A, etal., Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5600-5. doi: 10.1073/pnas.0501769102. Epub 2005 Apr 4.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9173930   PMID:12140560   PMID:12939278   PMID:14701835   PMID:15723043   PMID:19028597   PMID:21378169   PMID:23376485  


Genomics

Comparative Map Data
Fbxo2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85163,876,079 - 163,881,508 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5163,875,757 - 163,881,508 (+)EnsemblGRCr8
mRatBN7.25158,592,926 - 158,598,355 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5158,592,925 - 158,598,355 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5161,309,703 - 161,315,130 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05163,131,494 - 163,136,941 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05163,087,839 - 163,093,286 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05164,972,483 - 164,977,912 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5164,972,480 - 164,977,916 (+)Ensemblrn6Rnor6.0
Rnor_5.05168,630,521 - 168,635,950 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45165,239,080 - 165,244,509 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5156,871,142 - 156,876,571 (+)NCBICelera
RGSC_v3.15165,249,267 - 165,254,697 (+)NCBI
Cytogenetic Map5q36NCBI
FBXO2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38111,648,387 - 11,654,429 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl111,637,018 - 11,655,785 (-)Ensemblhg38GRCh38
GRCh37111,708,444 - 11,714,486 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36111,631,035 - 11,637,326 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34111,642,715 - 11,649,005NCBI
Celera110,820,505 - 10,826,801 (-)NCBICelera
Cytogenetic Map1p36.22NCBI
HuRef110,862,510 - 10,868,984 (-)NCBIHuRef
CHM1_1111,696,402 - 11,702,875 (-)NCBICHM1_1
T2T-CHM13v2.0111,192,423 - 11,198,481 (-)NCBIT2T-CHM13v2.0
Fbxo2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394148,244,605 - 148,250,874 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4148,245,078 - 148,250,881 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm384148,160,198 - 148,166,420 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4148,160,621 - 148,166,424 (+)Ensemblmm10GRCm38
MGSCv374147,534,777 - 147,540,526 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364147,004,468 - 147,010,217 (+)NCBIMGSCv36mm8
Celera4150,422,125 - 150,427,887 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map478.68NCBI
Fbxo2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554862,212,001 - 2,218,017 (+)Ensembl
ChiLan1.0NW_0049554862,212,001 - 2,217,260 (+)NCBIChiLan1.0ChiLan1.0
FBXO2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21216,571,838 - 216,577,899 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11215,217,956 - 215,224,017 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0110,408,853 - 10,415,174 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1111,626,713 - 11,633,171 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl111,626,713 - 11,633,171 (-)EnsemblpanPan2panpan1.1
FBXO2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1284,563,256 - 84,568,507 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl284,556,547 - 84,568,491 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha281,095,467 - 81,100,690 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0285,226,074 - 85,231,298 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl285,226,182 - 85,231,052 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1281,975,039 - 81,980,259 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0282,975,760 - 82,980,978 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0284,038,529 - 84,043,752 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fbxo2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505834,696,457 - 34,701,333 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936474521,123 - 526,959 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936474521,235 - 526,151 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXO2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl671,740,677 - 71,748,923 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1671,740,647 - 71,747,265 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2665,660,557 - 65,663,671 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FBXO2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120120,136,630 - 120,144,119 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20120,136,702 - 120,144,258 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605424,005,047 - 24,011,590 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbxo2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248181,299,067 - 1,309,667 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248181,300,191 - 1,311,245 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Fbxo2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1112,613,658 - 12,619,413 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Fbxo2
8 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:221
Count of miRNA genes:153
Interacting mature miRNAs:169
Transcripts:ENSRNOT00000012670
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5130249266172190305Rat
1354583Despr3Despair related QTL34.980.0002locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)5132930505172190305Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5141212838172190305Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5149642129171146538Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5160111176171146538Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5133789363172190305Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5134369199172190305Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5136631198172190305Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5156396728172190305Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5133081618172190305Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5138002522170842766Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5133270647172190305Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5160071170172129029Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)5141764300172190305Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5133789363172190305Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5148093485172129029Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5125969677172190305Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5156396728167181764Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5131708216172190305Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5149661912166600247Rat
1298090Bp155Blood pressure QTL 1553.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)5156289283171137955Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133081618172190305Rat

Markers in Region
RH136768  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25158,598,218 - 158,598,317 (+)MAPPERmRatBN7.2
Rnor_6.05164,977,776 - 164,977,874NCBIRnor6.0
Rnor_5.05168,635,814 - 168,635,912UniSTSRnor5.0
RGSC_v3.45165,244,373 - 165,244,471UniSTSRGSC3.4
Celera5156,876,435 - 156,876,533UniSTS
RH 3.4 Map51103.9UniSTS
Cytogenetic Map5q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
15 4 35 158 72 71 40 55 40 6 255 119 10 135 78 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000012670   ⟹   ENSRNOP00000012670
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5158,592,926 - 158,598,355 (+)Ensembl
Rnor_6.0 Ensembl5164,972,480 - 164,977,916 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000115135   ⟹   ENSRNOP00000076638
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5158,595,706 - 158,598,355 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119733   ⟹   ENSRNOP00000090623
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5163,876,124 - 163,881,508 (+)Ensembl
mRatBN7.2 Ensembl5158,592,925 - 158,598,355 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119831   ⟹   ENSRNOP00000089724
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5163,875,757 - 163,881,488 (+)Ensembl
mRatBN7.2 Ensembl5158,593,933 - 158,598,355 (+)Ensembl
RefSeq Acc Id: NM_053511   ⟹   NP_445963
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85163,876,079 - 163,881,508 (+)NCBI
mRatBN7.25158,592,926 - 158,598,355 (+)NCBI
Rnor_6.05164,972,483 - 164,977,912 (+)NCBI
Rnor_5.05168,630,521 - 168,635,950 (+)NCBI
RGSC_v3.45165,239,080 - 165,244,509 (+)RGD
Celera5156,871,142 - 156,876,571 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_445963 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC97505 (Get FASTA)   NCBI Sequence Viewer  
  EDL81115 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000089724
  ENSRNOP00000089724.2
  ENSRNOP00000090623.2
RefSeq Acc Id: NP_445963   ⟸   NM_053511
- UniProtKB: G3V774 (UniProtKB/TrEMBL),   A6IU64 (UniProtKB/TrEMBL),   Q9Z1X8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000012670   ⟸   ENSRNOT00000012670
Ensembl Acc Id: ENSRNOP00000089724   ⟸   ENSRNOT00000119831
Ensembl Acc Id: ENSRNOP00000076638   ⟸   ENSRNOT00000115135
Ensembl Acc Id: ENSRNOP00000090623   ⟸   ENSRNOT00000119733
Protein Domains
F-box   FBA

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V774-F1-model_v2 AlphaFold G3V774 1-296 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694259
Promoter ID:EPDNEW_R4784
Type:single initiation site
Name:Fbxo2_1
Description:F-box protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05164,972,448 - 164,972,508EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621751 AgrOrtholog
BioCyc Gene G2FUF-39172 BioCyc
Ensembl Genes ENSRNOG00000009409 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000119733.2 UniProtKB/TrEMBL
  ENSRNOT00000119831 ENTREZGENE
  ENSRNOT00000119831.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1280.50 UniProtKB/TrEMBL
  Galactose-binding domain-like UniProtKB/TrEMBL
InterPro F-box-assoc_dom UniProtKB/TrEMBL
  F-box_dom_cyclin-like UniProtKB/TrEMBL
  F-box_dom_like UniProtKB/TrEMBL
  F-box_only UniProtKB/TrEMBL
  Galactose-bd-like UniProtKB/TrEMBL
KEGG Report rno:85273 UniProtKB/TrEMBL
NCBI Gene 85273 ENTREZGENE
PANTHER F-BOX ONLY PROTEIN 2 UniProtKB/TrEMBL
  PTHR12125 UniProtKB/TrEMBL
Pfam F-box-like UniProtKB/TrEMBL
  FBA UniProtKB/TrEMBL
PhenoGen Fbxo2 PhenoGen
PROSITE FBA UniProtKB/TrEMBL
  FBOX UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009409 RatGTEx
SMART FBA UniProtKB/TrEMBL
Superfamily-SCOP F-box_dom_Skp2-like UniProtKB/TrEMBL
  Gal_bind_like UniProtKB/TrEMBL
UniProt A0A8I6A9Y7_RAT UniProtKB/TrEMBL
  A0A8I6AAF5_RAT UniProtKB/TrEMBL
  A6IU64 ENTREZGENE, UniProtKB/TrEMBL
  G3V774 ENTREZGENE
  Q9Z1X8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-25 Fbxo2  F-box protein 2  Fbxo2  F-box only protein 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Fbxo2  F-box only protein 2    neural F box protein NFB42  Name updated 1299863 APPROVED
2002-08-07 Fbxo2  neural F box protein NFB42      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized primarily to the cytoplasm of neurons 632756
gene_expression enriched in all major areas of the adult brain 632756