Ero1a (endoplasmic reticulum oxidoreductase 1 alpha) - Rat Genome Database

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Gene: Ero1a (endoplasmic reticulum oxidoreductase 1 alpha) Rattus norvegicus
Analyze
Symbol: Ero1a
Name: endoplasmic reticulum oxidoreductase 1 alpha
RGD ID: 621713
Description: Predicted to enable protein-disulfide reductase activity and thiol oxidase activity. Involved in cellular response to hypoxia. Located in dendrite. Orthologous to human ERO1A (endoplasmic reticulum oxidoreductase 1 alpha); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: endoplasmic oxidoreductin-1-like protein; endoplasmic reticulum oxidoreductase alpha; endoplasmic reticulum oxidoreductin-1-like protein; ERO1-L; ERO1-L-alpha; ERO1-like (S. cerevisiae); ERO1-like protein alpha; Ero1l; global ischemia-induced protein 11; LOC360278; oxidoreductin-1-L-alpha
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81520,974,771 - 21,010,170 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1520,972,679 - 21,018,039 (-)EnsemblGRCr8
mRatBN7.21518,495,037 - 18,530,440 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1518,492,945 - 18,530,478 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1521,289,698 - 21,325,207 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01522,246,643 - 22,282,158 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01520,503,217 - 20,538,731 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01519,619,947 - 19,655,381 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1519,619,973 - 19,655,381 (-)Ensemblrn6Rnor6.0
Rnor_5.01523,585,168 - 23,620,355 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41521,169,438 - 21,205,536 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1518,923,324 - 18,958,689 (-)NCBICelera
RGSC_v3.11521,169,450 - 21,205,536NCBI
Cytogenetic Map15p14NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
1H-pyrazole  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
adefovir pivoxil  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
antimycin A  (ISO)
apocynin  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzene-1,2,4-triol  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (EXP,ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
calyculin A  (ISO)
carbon monoxide  (EXP)
chloroacetaldehyde  (ISO)
chlorogenic acid  (EXP)
chlorpromazine  (EXP)
chromium(6+)  (ISO)
cidofovir anhydrous  (ISO)
cobalt atom  (EXP)
cobalt dichloride  (EXP,ISO)
cyclosporin A  (ISO)
D-glucose  (EXP,ISO)
decabromodiphenyl ether  (EXP,ISO)
deguelin  (ISO)
desferrioxamine B  (EXP,ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
diclofenac  (ISO)
dioxygen  (EXP,ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
enzyme inhibitor  (ISO)
ethanol  (ISO)
ethidium  (ISO)
ethyl methanesulfonate  (ISO)
Evodiamine  (ISO)
fenofibrate  (EXP)
fenpyroximate  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
furfural  (ISO)
gentamycin  (EXP)
glucose  (EXP,ISO)
gold atom  (ISO)
gold(0)  (ISO)
homocysteine  (ISO)
ifosfamide  (ISO)
indometacin  (ISO)
isoniazide  (ISO)
ivermectin  (ISO)
ketoconazole  (EXP)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
metformin  (EXP)
methyl methanesulfonate  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
nickel dichloride  (EXP,ISO)
nickel subsulfide  (ISO)
NMS-873  (ISO)
ochratoxin A  (ISO)
okadaic acid  (EXP)
paracetamol  (ISO)
parthenolide  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
Pf-06840003  (ISO)
picoxystrobin  (ISO)
propiconazole  (ISO)
pyruvic acid  (ISO)
rac-lactic acid  (ISO)
resveratrol  (EXP,ISO)
rotenone  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sirolimus  (EXP)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
sodium fluoride  (ISO)
sotorasib  (ISO)
succimer  (ISO)
sulforaphane  (EXP)
sunitinib  (ISO)
T-2 toxin  (EXP)
tacrolimus hydrate  (ISO)
tebufenpyrad  (ISO)
temozolomide  (ISO)
Tesaglitazar  (EXP)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetrathiomolybdate(2-)  (ISO)
thapsigargin  (EXP,ISO)
thifluzamide  (ISO)
trametinib  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
uridine  (ISO)
valproic acid  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Ero1-L, an ischemia-inducible gene from rat brain with homology to global ischemia-induced gene 11 (Giig11), is localized to neuronal dendrites by a dispersed identifier (ID) element-dependent mechanism. Chen D, etal., J Neurochem 2003 May;85(3):670-9.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. The cellular oxygen tension regulates expression of the endoplasmic oxidoreductase ERO1-Lalpha. Gess B, etal., Eur J Biochem. 2003 May;270(10):2228-35.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Accelerated senescence in kidneys of low-birth-weight rats after catch-up growth. Luyckx VA, etal., Am J Physiol Renal Physiol. 2009 Dec;297(6):F1697-705. doi: 10.1152/ajprenal.00462.2009. Epub 2009 Oct 14.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:10671517   PMID:11707400   PMID:15601821   PMID:18492766   PMID:19752026   PMID:19946888   PMID:20308425   PMID:22981861   PMID:23589496   PMID:25122773   PMID:25452428   PMID:30058081  
PMID:31176989   PMID:32626998   PMID:35086342  


Genomics

Comparative Map Data
Ero1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81520,974,771 - 21,010,170 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1520,972,679 - 21,018,039 (-)EnsemblGRCr8
mRatBN7.21518,495,037 - 18,530,440 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1518,492,945 - 18,530,478 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1521,289,698 - 21,325,207 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01522,246,643 - 22,282,158 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01520,503,217 - 20,538,731 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01519,619,947 - 19,655,381 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1519,619,973 - 19,655,381 (-)Ensemblrn6Rnor6.0
Rnor_5.01523,585,168 - 23,620,355 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41521,169,438 - 21,205,536 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1518,923,324 - 18,958,689 (-)NCBICelera
RGSC_v3.11521,169,450 - 21,205,536NCBI
Cytogenetic Map15p14NCBI
ERO1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381452,639,915 - 52,695,558 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1452,639,915 - 52,696,025 (-)Ensemblhg38GRCh38
GRCh371453,106,633 - 53,162,276 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361452,178,355 - 52,232,169 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341452,178,356 - 52,232,169NCBI
Celera1432,976,214 - 33,030,020 (-)NCBICelera
Cytogenetic Map14q22.1NCBI
HuRef1433,269,409 - 33,323,505 (-)NCBIHuRef
CHM1_11453,047,533 - 53,101,335 (-)NCBICHM1_1
T2T-CHM13v2.01446,847,757 - 46,903,365 (-)NCBIT2T-CHM13v2.0
Ero1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391445,520,544 - 45,556,029 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1445,520,544 - 45,556,228 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381445,283,087 - 45,318,572 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1445,283,087 - 45,318,771 (-)Ensemblmm10GRCm38
MGSCv371445,903,996 - 45,938,202 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361444,206,198 - 44,240,404 (-)NCBIMGSCv36mm8
Celera1441,464,909 - 41,498,352 (-)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1422.86NCBI
Ero1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540910,502,554 - 10,530,376 (+)Ensembl
ChiLan1.0NW_00495540910,495,892 - 10,533,383 (+)NCBIChiLan1.0ChiLan1.0
ERO1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21553,770,587 - 53,826,868 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11452,987,098 - 53,043,159 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01433,236,087 - 33,292,127 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11451,520,048 - 51,575,792 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1451,520,048 - 51,575,798 (-)EnsemblpanPan2panpan1.1
ERO1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1828,864,642 - 28,913,864 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl828,864,925 - 28,914,368 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha828,609,553 - 28,658,814 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0829,030,663 - 29,080,527 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl829,029,758 - 29,081,013 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1828,704,719 - 28,754,465 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0828,776,955 - 28,826,980 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0829,105,676 - 29,155,434 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ero1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864076,380,350 - 76,425,758 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366972,154,065 - 2,199,926 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366972,154,517 - 2,199,913 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ERO1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1182,265,261 - 182,318,195 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11182,268,651 - 182,318,147 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21202,436,374 - 202,588,694 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ERO1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12429,708,521 - 29,777,939 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2429,717,710 - 29,777,918 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605317,992,077 - 18,051,108 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ero1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473116,425,437 - 16,473,043 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473116,425,496 - 16,476,120 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ero1a
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11277,722,061 - 77,755,378 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ero1a
246 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:364
Count of miRNA genes:226
Interacting mature miRNAs:277
Transcripts:ENSRNOT00000009404
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15231575947315759Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15278592347785923Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15139411584Rat
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15132342855Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15144836456Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
5685002Bss103Bone structure and strength QTL 1032.8tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)151691152132439851Rat

Markers in Region
RH143391  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21518,530,310 - 18,530,410 (+)MAPPERmRatBN7.2
Rnor_6.01519,655,252 - 19,655,351NCBIRnor6.0
Rnor_5.01523,620,226 - 23,620,325UniSTSRnor5.0
RGSC_v3.41521,205,407 - 21,205,506UniSTSRGSC3.4
Celera1518,958,560 - 18,958,659UniSTS
RH 3.4 Map15145.2UniSTS
Cytogenetic Map15p14UniSTS
AI599520  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21518,493,244 - 18,493,392 (+)MAPPERmRatBN7.2
Rnor_6.01519,618,155 - 19,618,302NCBIRnor6.0
Rnor_5.01523,583,376 - 23,583,523UniSTSRnor5.0
RGSC_v3.41521,167,646 - 21,167,793UniSTSRGSC3.4
Celera1518,921,532 - 18,921,679UniSTS
RH 3.4 Map15149.6UniSTS
Cytogenetic Map15p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000009404   ⟹   ENSRNOP00000009404
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1520,972,679 - 21,018,039 (-)Ensembl
mRatBN7.2 Ensembl1518,495,838 - 18,530,477 (-)Ensembl
Rnor_6.0 Ensembl1519,619,973 - 19,655,381 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100831   ⟹   ENSRNOP00000094942
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1520,972,679 - 21,010,177 (-)Ensembl
mRatBN7.2 Ensembl1518,492,946 - 18,530,478 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116811   ⟹   ENSRNOP00000094430
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1520,972,679 - 21,010,177 (-)Ensembl
mRatBN7.2 Ensembl1518,492,945 - 18,530,447 (-)Ensembl
RefSeq Acc Id: NM_138528   ⟹   NP_612537
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81520,974,771 - 21,010,170 (-)NCBI
mRatBN7.21518,495,037 - 18,530,440 (-)NCBI
Rnor_6.01519,619,947 - 19,655,381 (-)NCBI
Rnor_5.01523,585,168 - 23,620,355 (-)NCBI
RGSC_v3.41521,169,438 - 21,205,536 (-)RGD
Celera1518,923,324 - 18,958,689 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001420791 (Get FASTA)   NCBI Sequence Viewer  
  NP_612537 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAK01420 (Get FASTA)   NCBI Sequence Viewer  
  AAL61547 (Get FASTA)   NCBI Sequence Viewer  
  AAL61548 (Get FASTA)   NCBI Sequence Viewer  
  AAL96669 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000094430
  ENSRNOP00000094430.1
GenBank Protein Q8R4A1 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_612537   ⟸   NM_138528
- Peptide Label: precursor
- UniProtKB: Q8VH30 (UniProtKB/Swiss-Prot),   Q8VH29 (UniProtKB/Swiss-Prot),   Q8R4A1 (UniProtKB/Swiss-Prot),   A0A8I6B1Q4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000009404   ⟸   ENSRNOT00000009404
Ensembl Acc Id: ENSRNOP00000094942   ⟸   ENSRNOT00000100831
Ensembl Acc Id: ENSRNOP00000094430   ⟸   ENSRNOT00000116811

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8R4A1-F1-model_v2 AlphaFold Q8R4A1 1-464 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699595
Promoter ID:EPDNEW_R10118
Type:multiple initiation site
Name:Ero1a_1
Description:endoplasmic reticulum oxidoreductase 1 alpha
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01519,655,416 - 19,655,476EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621713 AgrOrtholog
BioCyc Gene G2FUF-14222 BioCyc
Ensembl Genes ENSRNOG00000006462 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000116811 ENTREZGENE
  ENSRNOT00000116811.1 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7099384 IMAGE-MGC_LOAD
InterPro Ero1 UniProtKB/Swiss-Prot
  ERO1-like_sf UniProtKB/Swiss-Prot
KEGG Report rno:171562 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91493 IMAGE-MGC_LOAD
NCBI Gene 171562 ENTREZGENE
PANTHER ERO1-LIKE PROTEIN ALPHA UniProtKB/Swiss-Prot
  PTHR12613 UniProtKB/Swiss-Prot
Pfam ERO1 UniProtKB/Swiss-Prot
PhenoGen Ero1a PhenoGen
PIRSF ERO1 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000006462 RatGTEx
Superfamily-SCOP SSF110019 UniProtKB/Swiss-Prot
UniProt A0A8I6B1Q4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2UI53 ENTREZGENE, UniProtKB/TrEMBL
  A6KDZ5 ENTREZGENE, UniProtKB/TrEMBL
  ERO1A_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q8VH29 ENTREZGENE
  Q8VH30 ENTREZGENE
UniProt Secondary Q8VH29 UniProtKB/Swiss-Prot
  Q8VH30 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-07-07 Ero1a  endoplasmic reticulum oxidoreductase 1 alpha  Ero1a  endoplasmic reticulum oxidoreductase alpha  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-06-24 Ero1a  endoplasmic reticulum oxidoreductase alpha  Ero1l  ERO1-like (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-02-23 Ero1l  ERO1-like (S. cerevisiae)  Ero1l_predicted  ERO1-like (S. cerevisiae) (predicted)  Data merged from RGD:1308220 737654 APPROVED
2005-01-20 Ero1l  ERO1-like (S. cerevisiae)      Symbol and Name status set to approved 1299863 APPROVED
2005-01-12 Ero1l_predicted  ERO1-like (S. cerevisiae) (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-08-07 Ero1l  ERO1-like (S. cerevisiae)      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_homology homologous to ischemia-inducible gene 11(Giig11) 632668
gene_process involved in oxidative endoplasmic reticulum protein folding 632668