Pip4k2a (phosphatidylinositol-5-phosphate 4-kinase type 2 alpha) - Rat Genome Database

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Gene: Pip4k2a (phosphatidylinositol-5-phosphate 4-kinase type 2 alpha) Rattus norvegicus
Analyze
Symbol: Pip4k2a
Name: phosphatidylinositol-5-phosphate 4-kinase type 2 alpha
RGD ID: 621708
Description: Predicted to enable 1-phosphatidylinositol-4-phosphate 5-kinase activity; 1-phosphatidylinositol-5-phosphate 4-kinase activity; and protein homodimerization activity. Predicted to be involved in several processes, including 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process; autophagosome-lysosome fusion; and megakaryocyte development. Predicted to be located in autophagosome; cytosol; and lysosome. Predicted to be active in plasma membrane. Orthologous to human PIP4K2A (phosphatidylinositol-5-phosphate 4-kinase type 2 alpha); PARTICIPATES IN phosphoinositide metabolic pathway; inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha; 1-phosphatidylinositol-5-phosphate 4-kinase 2-alpha; 1-phosphatidylinositol-5-phosphate 4-kinase A; diphosphoinositide kinase 2-alpha; LOC100363127; LOC100909950; phosphatidylinositol 5-phosphate 4-kinase type II alpha; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha-like; phosphatidylinositol-4-phosphate 5-kinase, type II, alpha; phosphatidylinositol-5-phosphate 4-kinase type-2 alpha; phosphatidylinositol-5-phosphate 4-kinase type-2 alpha-like; phosphatidylinositol-5-phosphate 4-kinase, type II, alpha; PI(5)P 4-kinase type II alpha; PIP4KII-alpha; Pip5k2a; PIPK2 alpha; ptdIns(5)P-4-kinase isoform 2-alpha; uncharacterized LOC100909950
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81786,405,080 - 86,576,597 (-)NCBIGRCr8
mRatBN7.21781,496,669 - 81,668,180 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1781,496,670 - 81,668,029 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1784,970,346 - 85,134,961 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01788,805,740 - 88,970,367 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01782,822,473 - 82,987,105 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01785,533,056 - 85,748,843 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01787,260,013 - 87,284,895 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01787,360,739 - 87,463,987 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41792,950,531 - 93,111,944 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11792,963,045 - 93,122,777NCBI
Celera1780,777,213 - 80,940,203 (-)NCBICelera
Cytogenetic Map17q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
melanoma  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-tribromophenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
butan-1-ol  (ISO)
cadmium dichloride  (ISO)
carbonyl sulfide  (EXP)
chlorpyrifos  (EXP)
choline  (ISO)
clobetasol  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (EXP)
Dibutyl phosphate  (ISO)
diethylstilbestrol  (ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
folic acid  (ISO)
fonofos  (ISO)
formaldehyde  (ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
isoflurane  (ISO)
ivermectin  (ISO)
ketamine  (EXP)
L-methionine  (ISO)
mercury dibromide  (ISO)
methapyrilene  (ISO)
methimazole  (EXP)
nickel atom  (ISO)
paracetamol  (ISO)
parathion  (ISO)
phenylmercury acetate  (ISO)
phenytoin  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
rifampicin  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
temozolomide  (ISO)
terbufos  (ISO)
testosterone  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
triphenyl phosphate  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
autophagosome  (IEA,ISO)
cytosol  (IEA,ISO)
lysosome  (IEA,ISO,ISS)
nucleus  (IEA)
photoreceptor inner segment  (IEA)
photoreceptor outer segment  (IEA)
plasma membrane  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family. Ishihara H, etal., J Biol Chem 1998 Apr 10;273(15):8741-8.
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:16434494   PMID:22206666   PMID:23758345   PMID:25495341   PMID:25578879  


Genomics

Comparative Map Data
Pip4k2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81786,405,080 - 86,576,597 (-)NCBIGRCr8
mRatBN7.21781,496,669 - 81,668,180 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1781,496,670 - 81,668,029 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1784,970,346 - 85,134,961 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01788,805,740 - 88,970,367 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01782,822,473 - 82,987,105 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01785,533,056 - 85,748,843 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01787,260,013 - 87,284,895 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01787,360,739 - 87,463,987 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41792,950,531 - 93,111,944 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11792,963,045 - 93,122,777NCBI
Celera1780,777,213 - 80,940,203 (-)NCBICelera
Cytogenetic Map17q12.3NCBI
PIP4K2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381022,534,854 - 22,714,578 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1022,534,854 - 22,714,578 (-)EnsemblGRCh38hg38GRCh38
GRCh371022,823,783 - 23,003,507 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361022,863,772 - 23,043,509 (-)NCBINCBI36Build 36hg18NCBI36
Build 341022,865,828 - 23,043,490NCBI
Celera1022,511,468 - 22,691,158 (-)NCBICelera
Cytogenetic Map10p12.2NCBI
HuRef1022,484,658 - 22,664,398 (-)NCBIHuRef
CHM1_11022,824,227 - 23,003,964 (-)NCBICHM1_1
T2T-CHM13v2.01022,553,890 - 22,733,579 (-)NCBIT2T-CHM13v2.0
Pip4k2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39218,847,066 - 19,003,101 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl218,847,066 - 19,002,937 (-)EnsemblGRCm39 Ensembl
GRCm38218,842,255 - 18,998,291 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl218,842,255 - 18,998,126 (-)EnsemblGRCm38mm10GRCm38
MGSCv37218,763,883 - 18,919,748 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36218,760,014 - 18,915,870 (-)NCBIMGSCv36mm8
Celera218,734,163 - 18,892,750 (-)NCBICelera
Cytogenetic Map2A3NCBI
Pip4k2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554296,336,355 - 6,399,672 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554296,231,135 - 6,399,672 (+)NCBIChiLan1.0ChiLan1.0
PIP4K2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2835,214,901 - 35,394,214 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11035,220,226 - 35,399,538 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01022,691,355 - 22,870,628 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11023,066,771 - 23,141,230 (-)NCBIpanpan1.1PanPan1.1panPan2
PIP4K2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1210,464,019 - 10,642,365 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl210,463,010 - 10,640,327 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha29,157,521 - 9,335,592 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.028,663,138 - 8,841,553 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl28,663,029 - 8,840,895 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.128,027,620 - 8,205,381 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.028,110,958 - 8,289,331 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.028,279,324 - 8,457,701 (+)NCBIUU_Cfam_GSD_1.0
Pip4k2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934422,420,301 - 22,576,740 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365205,383,737 - 5,540,203 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365205,383,737 - 5,540,176 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIP4K2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1052,224,389 - 52,408,922 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11052,224,367 - 52,408,928 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21057,880,198 - 58,064,685 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PIP4K2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1922,306,307 - 22,482,074 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl922,306,312 - 22,481,954 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605128,057,994 - 28,238,500 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pip4k2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247965,962,999 - 6,113,087 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247965,963,005 - 6,113,081 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pip4k2a
1188 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:715
Count of miRNA genes:305
Interacting mature miRNAs:395
Transcripts:ENSRNOT00000022375
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8694181Bw151Body weight QTL 1514.360.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
1358295Aocep1Aortic cell protein QTL 16.17e-07thoracic aorta cellular protein amount (VT:0010598)aortic cell percentage174099000585990005Rat
12904736Cm121Cardiac mass QTL 1210.043heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)177177462182479847Rat
7411575Bw140Body weight QTL 14030.20.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
2317060Aia26Adjuvant induced arthritis QTL 263.22joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)173828150983281509Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175349882882479847Rat
7411577Bw141Body weight QTL 1410.001body mass (VT:0001259)body weight gain (CMO:0000420)176261951686533673Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175090909986022412Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)174992015486533673Rat
2317045Aia11Adjuvant induced arthritis QTL 114.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)176078142686533673Rat
2317054Aia12Adjuvant induced arthritis QTL 124.24joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)173828150983281509Rat
2302365Gluco40Glucose level QTL 404.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)175724684382046127Rat
2303580Gluco49Glucose level QTL 492blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)175004027186533673Rat

Markers in Region
RH143686  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21781,497,324 - 81,497,425 (+)MAPPERmRatBN7.2
Rnor_6.01785,533,712 - 85,533,812NCBIRnor6.0
Rnor_5.01787,260,669 - 87,260,769UniSTSRnor5.0
RGSC_v3.41792,951,187 - 92,951,287UniSTSRGSC3.4
Celera1780,777,869 - 80,777,969UniSTS
RH 3.4 Map17831.5UniSTS
Cytogenetic Map17q12.3UniSTS
RH142512  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21781,605,835 - 81,605,978 (+)MAPPERmRatBN7.2
Rnor_6.01786,695,393 - 86,695,535NCBIRnor6.0
Rnor_6.01785,686,686 - 85,686,828NCBIRnor6.0
Rnor_5.01788,400,558 - 88,400,700UniSTSRnor5.0
Rnor_5.01787,402,059 - 87,402,201UniSTSRnor5.0
RGSC_v3.41793,049,180 - 93,049,322UniSTSRGSC3.4
Celera1780,878,300 - 80,878,442UniSTS
RH 3.4 Map17812.5UniSTS
Cytogenetic Map17q12.3UniSTS
RH139055  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21781,498,774 - 81,498,904 (+)MAPPERmRatBN7.2
Rnor_6.01785,535,162 - 85,535,291NCBIRnor6.0
Rnor_5.01787,262,119 - 87,262,248UniSTSRnor5.0
RGSC_v3.41792,952,637 - 92,952,766UniSTSRGSC3.4
Celera1780,779,319 - 80,779,448UniSTS
RH 3.4 Map17834.5UniSTS
Cytogenetic Map17q12.3UniSTS
AI577465  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21781,496,740 - 81,496,842 (+)MAPPERmRatBN7.2
Rnor_6.01785,533,128 - 85,533,229NCBIRnor6.0
Rnor_5.01787,260,085 - 87,260,186UniSTSRnor5.0
RGSC_v3.41792,950,603 - 92,950,704UniSTSRGSC3.4
Celera1780,777,285 - 80,777,386UniSTS
RH 3.4 Map17831.4UniSTS
Cytogenetic Map17q12.3UniSTS
BE118396  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21781,499,475 - 81,499,636 (+)MAPPERmRatBN7.2
Rnor_6.01785,535,861 - 85,536,021NCBIRnor6.0
Rnor_5.01787,262,818 - 87,262,978UniSTSRnor5.0
RGSC_v3.41792,953,336 - 92,953,496UniSTSRGSC3.4
Celera1780,780,018 - 80,780,178UniSTS
RH 3.4 Map17833.5UniSTS
Cytogenetic Map17q12.3UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSRNOT00000022375   ⟹   ENSRNOP00000022375
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1781,496,670 - 81,668,029 (-)Ensembl
RefSeq Acc Id: NM_053926   ⟹   NP_446378
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81786,405,080 - 86,576,430 (-)NCBI
mRatBN7.21781,496,669 - 81,668,029 (-)NCBI
Rnor_6.01785,533,056 - 85,748,843 (-)NCBI
Rnor_5.01787,260,013 - 87,284,895 (-)NCBI
Rnor_5.01787,360,739 - 87,463,987 (-)NCBI
RGSC_v3.41792,950,531 - 93,111,944 (-)RGD
Celera1780,777,213 - 80,940,203 (-)RGD
Sequence:
RefSeq Acc Id: XM_039095304   ⟹   XP_038951232
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81786,408,921 - 86,576,597 (-)NCBI
mRatBN7.21781,496,669 - 81,668,180 (-)NCBI
RefSeq Acc Id: XM_039095305   ⟹   XP_038951233
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81786,405,080 - 86,459,418 (-)NCBI
mRatBN7.21781,496,669 - 81,551,005 (-)NCBI
RefSeq Acc Id: XM_039095306   ⟹   XP_038951234
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81786,405,080 - 86,576,597 (-)NCBI
mRatBN7.21781,496,669 - 81,668,179 (-)NCBI
RefSeq Acc Id: NP_446378   ⟸   NM_053926
- UniProtKB: Q9R0I8 (UniProtKB/Swiss-Prot),   A6JM97 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038951232   ⟸   XM_039095304
- Peptide Label: isoform X1
- UniProtKB: A6JM97 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951234   ⟸   XM_039095306
- Peptide Label: isoform X3
- UniProtKB: A6JM97 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951233   ⟸   XM_039095305
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000022375   ⟸   ENSRNOT00000022375
Protein Domains
PIPK

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LX22-F1-model_v2 AlphaFold F1LX22 1-194 view protein structure
AF-Q9R0I8-F1-model_v2 AlphaFold Q9R0I8 1-406 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621708 AgrOrtholog
BioCyc Gene G2FUF-8548 BioCyc
BioCyc Pathway PWY-6351 [D-myo-inositol (1,4,5)-trisphosphate biosynthesis] BioCyc
  PWY-6367 [D-myo-inositol-5-phosphate metabolism] BioCyc
BioCyc Pathway Image PWY-6351 BioCyc
  PWY-6367 BioCyc
Ensembl Genes ENSRNOG00000016670 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055010925 UniProtKB/Swiss-Prot
  ENSRNOG00060020405 UniProtKB/Swiss-Prot
  ENSRNOG00065003110 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000022375 UniProtKB/TrEMBL
  ENSRNOT00000022375.8 UniProtKB/Swiss-Prot
  ENSRNOT00055018504 UniProtKB/Swiss-Prot
  ENSRNOT00060035398 UniProtKB/Swiss-Prot
  ENSRNOT00065004375 UniProtKB/Swiss-Prot
Gene3D-CATH 2-Layer Sandwich UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.800.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro PInositol-4-P-4/5-kinase_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PInositol-4-P-5-kinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PInositol-4-P-5-kinase_core UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PInositol-4-P-5-kinase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:116723 UniProtKB/Swiss-Prot
NCBI Gene 116723 ENTREZGENE
PANTHER PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE TYPE-2 ALPHA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR23086 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PIP5K UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pip4k2a PhenoGen
PROSITE PIPK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016670 RatGTEx
  ENSRNOG00055010925 RatGTEx
  ENSRNOG00060020405 RatGTEx
  ENSRNOG00065003110 RatGTEx
SMART PIPKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SAICAR synthase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6JM97 ENTREZGENE, UniProtKB/TrEMBL
  F1LX22_RAT UniProtKB/TrEMBL
  PI42A_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Pip4k2a  phosphatidylinositol-5-phosphate 4-kinase type 2 alpha  LOC100909950  uncharacterized LOC100909950  Data merged from RGD:6501048 737654 PROVISIONAL
2016-04-20 Pip4k2a  phosphatidylinositol-5-phosphate 4-kinase type 2 alpha  Pip4k2a  phosphatidylinositol-5-phosphate 4-kinase, type II, alpha  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-04-17 Pip4k2a  phosphatidylinositol-5-phosphate 4-kinase, type II, alpha  LOC100363127  phosphatidylinositol-5-phosphate 4-kinase type-2 alpha-like  Data merged from RGD:2324762 737654 PROVISIONAL
2012-07-05 LOC100909950  uncharacterized LOC100909950      Symbol and Name status set to provisional 70820 PROVISIONAL
2010-05-12 LOC100363127  phosphatidylinositol-5-phosphate 4-kinase type-2 alpha-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-02-25 Pip4k2a  phosphatidylinositol-5-phosphate 4-kinase, type II, alpha  Pip5k2a  phosphatidylinositol-4-phosphate 5-kinase, type II, alpha  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-02-26 Pip5k2a  phosphatidylinositol-4-phosphate 5-kinase, type II, alpha      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Pip5k2a  phosphatidylinositol-4-phosphate 5-kinase, type II, alpha      Symbol and Name status set to provisional 70820 PROVISIONAL