Zfp423 (zinc finger protein 423) - Rat Genome Database

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Pathways
Gene: Zfp423 (zinc finger protein 423) Rattus norvegicus
Analyze
Symbol: Zfp423
Name: zinc finger protein 423
RGD ID: 621664
Description: Enables identical protein binding activity and sequence-specific DNA binding activity. Involved in negative regulation of DNA-templated transcription. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in nephronophthisis 14. Orthologous to human ZNF423 (zinc finger protein 423); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Olf-1/EBF associated Zn finger protein Roaz; olf1/EBF-associated zinc finger protein; Roaz; smad- and Olf-interacting zinc finger protein; Znf423
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81935,282,149 - 35,580,775 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1935,282,110 - 35,580,773 (+)EnsemblGRCr8
mRatBN7.21919,111,213 - 19,407,373 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1919,110,238 - 19,407,373 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1920,790,704 - 21,086,843 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01925,985,352 - 26,281,344 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01928,949,192 - 29,245,348 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01920,147,201 - 20,405,999 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1920,147,037 - 20,406,003 (+)Ensemblrn6Rnor6.0
Rnor_5.01931,166,356 - 31,417,977 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41920,475,864 - 20,739,236 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1919,045,848 - 19,288,099 (+)NCBICelera
RGSC_v3.11920,443,834 - 20,744,062 (+)NCBI
Cytogenetic Map19p11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
atrazine  (EXP,ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (EXP,ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
chrysene  (ISO)
clobetasol  (ISO)
clofazimine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (ISO)
cytarabine  (ISO)
decabromodiphenyl ether  (EXP)
dibenz[a,h]anthracene  (ISO)
dorsomorphin  (ISO)
ethanol  (ISO)
finasteride  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
gentamycin  (EXP)
L-methionine  (ISO)
lead(0)  (ISO)
lithium chloride  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
monosodium L-glutamate  (EXP)
N,N-diethyl-m-toluamide  (EXP)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
paracetamol  (ISO)
perfluorooctanoic acid  (EXP)
permethrin  (EXP)
pirinixic acid  (EXP,ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sulindac  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
tributylstannane  (ISO)
triflumizole  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Zfp423 Maintains White Adipocyte Identity through Suppression of the Beige Cell Thermogenic Gene Program. Shao M, etal., Cell Metab. 2016 Jun 14;23(6):1167-1184. doi: 10.1016/j.cmet.2016.04.023. Epub 2016 May 26.
8. Cloning and functional characterization of Roaz, a zinc finger protein that interacts with O/E-1 to regulate gene expression: implications for olfactory neuronal development. Tsai RY and Reed RR, J Neurosci. 1997 Jun 1;17(11):4159-69.
9. Identification of DNA recognition sequences and protein interaction domains of the multiple-Zn-finger protein Roaz. Tsai RY and Reed RR, Mol Cell Biol 1998 Nov;18(11):6447-56.
Additional References at PubMed
PMID:10660046   PMID:20547764   PMID:24913911  


Genomics

Comparative Map Data
Zfp423
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81935,282,149 - 35,580,775 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1935,282,110 - 35,580,773 (+)EnsemblGRCr8
mRatBN7.21919,111,213 - 19,407,373 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1919,110,238 - 19,407,373 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1920,790,704 - 21,086,843 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01925,985,352 - 26,281,344 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01928,949,192 - 29,245,348 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01920,147,201 - 20,405,999 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1920,147,037 - 20,406,003 (+)Ensemblrn6Rnor6.0
Rnor_5.01931,166,356 - 31,417,977 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41920,475,864 - 20,739,236 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1919,045,848 - 19,288,099 (+)NCBICelera
RGSC_v3.11920,443,834 - 20,744,062 (+)NCBI
Cytogenetic Map19p11NCBI
ZNF423
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381649,487,524 - 49,859,279 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1649,487,524 - 49,857,919 (-)Ensemblhg38GRCh38
GRCh371649,521,435 - 49,891,830 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361648,082,022 - 48,418,419 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341648,082,022 - 48,418,419NCBI
Celera1634,037,933 - 34,374,016 (-)NCBICelera
Cytogenetic Map16q12.1NCBI
HuRef1635,413,949 - 35,779,476 (-)NCBIHuRef
CHM1_11650,931,825 - 51,299,125 (-)NCBICHM1_1
T2T-CHM13v2.01655,285,346 - 55,656,988 (-)NCBIT2T-CHM13v2.0
Zfp423
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39888,388,438 - 88,688,665 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl888,388,438 - 88,686,223 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38887,661,810 - 87,962,053 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl887,661,810 - 87,959,595 (-)Ensemblmm10GRCm38
MGSCv37890,185,709 - 90,483,494 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36890,551,915 - 90,849,700 (-)NCBIMGSCv36mm8
Celera891,927,923 - 92,193,957 (-)NCBICelera
Cytogenetic Map8C3NCBI
cM Map842.29NCBI
Znf423
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554337,700,734 - 8,009,451 (-)Ensembl
ChiLan1.0NW_0049554337,700,965 - 8,018,437 (-)NCBIChiLan1.0ChiLan1.0
ZNF423
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21858,945,567 - 59,311,916 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11664,850,814 - 65,217,052 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01629,748,405 - 30,118,999 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11648,635,379 - 48,969,776 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1648,639,118 - 48,969,727 (-)EnsemblpanPan2panpan1.1
ZNF423
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1265,512,342 - 65,778,410 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl265,438,842 - 65,778,407 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha262,021,969 - 62,355,695 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0265,995,487 - 66,329,228 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl265,987,645 - 66,329,218 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1262,818,056 - 63,152,768 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0263,837,882 - 64,171,956 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0264,726,999 - 65,060,818 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Znf423
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934956,632,360 - 56,889,357 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364752,699,702 - 3,010,912 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364752,699,722 - 2,956,734 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF423
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl634,932,597 - 35,299,688 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1634,929,286 - 35,299,695 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2630,708,117 - 31,005,158 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZNF423
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1535,281,679 - 35,657,045 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl535,278,652 - 35,621,956 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604740,921,545 - 41,224,662 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znf423
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247576,742,132 - 7,061,058 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247576,742,289 - 7,060,907 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Zfp423
1698 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:13
Count of miRNA genes:12
Interacting mature miRNAs:13
Transcripts:ENSRNOT00000020028
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19799775052997750Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)191922068964220689Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19799775052997750Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)19574806450748064Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)193128753251431640Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19799775052997750Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19799775052997750Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)192010930665109306Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat
61407Scl12Serum cholesterol level QTL 120.001blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)193009938347207961Rat

Markers in Region
D19Rat39  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21919,352,209 - 19,352,458 (+)MAPPERmRatBN7.2
Rnor_6.01920,350,843 - 20,351,091NCBIRnor6.0
Rnor_5.01931,363,477 - 31,363,725UniSTSRnor5.0
RGSC_v3.41920,683,784 - 20,684,033RGDRGSC3.4
RGSC_v3.41920,683,785 - 20,684,033UniSTSRGSC3.4
Celera1919,232,891 - 19,233,139UniSTS
RGSC_v3.11920,688,576 - 20,688,880RGD
FHH x ACI Map1921.16RGD
FHH x ACI Map1921.16UniSTS
Cytogenetic Map19p11UniSTS
D19Rat51  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01931,249,034 - 31,249,261NCBIRnor5.0
Rnor_5.01931,249,035 - 31,249,261NCBIRnor5.0
RGSC_v3.41920,551,182 - 20,551,408RGDRGSC3.4
RGSC_v3.41920,551,183 - 20,551,408UniSTSRGSC3.4
Celera1919,118,830 - 19,119,055UniSTS
RGSC_v3.11920,555,988 - 20,556,256RGD
FHH x ACI Map1921.2UniSTS
FHH x ACI Map1921.2RGD
Cytogenetic Map19p11UniSTS
AU046515  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81935,368,977 - 35,369,246 (+)Marker Load Pipeline
Rnor_6.01920,193,702 - 20,193,938NCBIRnor6.0
Rnor_5.01931,206,804 - 31,207,040UniSTSRnor5.0
Celera1919,076,601 - 19,076,869UniSTS
Cytogenetic Map19p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
14 12 67 164 91 90 59 57 59 6 316 157 11 143 78 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000020028   ⟹   ENSRNOP00000020028
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1935,345,764 - 35,580,773 (+)Ensembl
mRatBN7.2 Ensembl1919,172,352 - 19,407,373 (+)Ensembl
Rnor_6.0 Ensembl1920,147,037 - 20,406,003 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101491   ⟹   ENSRNOP00000082983
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1935,321,367 - 35,580,773 (+)Ensembl
mRatBN7.2 Ensembl1919,110,238 - 19,407,373 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101895   ⟹   ENSRNOP00000085196
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1935,284,662 - 35,580,773 (+)Ensembl
mRatBN7.2 Ensembl1919,111,230 - 19,407,373 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000148161   ⟹   ENSRNOP00000108545
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1935,284,668 - 35,580,773 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000153975   ⟹   ENSRNOP00000107589
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1935,447,473 - 35,580,773 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000163933   ⟹   ENSRNOP00000108072
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1935,282,110 - 35,580,773 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000172110   ⟹   ENSRNOP00000101941
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1935,299,684 - 35,580,773 (+)Ensembl
RefSeq Acc Id: NM_001393718   ⟹   NP_001380647
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81935,284,640 - 35,580,773 (+)NCBI
mRatBN7.21919,111,213 - 19,407,373 (+)NCBI
RefSeq Acc Id: XM_063278328   ⟹   XP_063134398
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81935,284,645 - 35,562,251 (+)NCBI
RefSeq Acc Id: XM_063278329   ⟹   XP_063134399
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81935,300,219 - 35,562,251 (+)NCBI
RefSeq Acc Id: XM_063278330   ⟹   XP_063134400
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81935,303,255 - 35,562,251 (+)NCBI
RefSeq Acc Id: XM_063278331   ⟹   XP_063134401
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81935,438,301 - 35,562,251 (+)NCBI
RefSeq Acc Id: XM_063278332   ⟹   XP_063134402
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81935,436,911 - 35,562,251 (+)NCBI
RefSeq Acc Id: XM_063278333   ⟹   XP_063134403
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81935,300,226 - 35,580,775 (+)NCBI
RefSeq Acc Id: XM_063278334   ⟹   XP_063134404
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81935,282,149 - 35,580,775 (+)NCBI
Ensembl Acc Id: ENSRNOP00000020028   ⟸   ENSRNOT00000020028
Ensembl Acc Id: ENSRNOP00000082983   ⟸   ENSRNOT00000101491
Ensembl Acc Id: ENSRNOP00000085196   ⟸   ENSRNOT00000101895
RefSeq Acc Id: NP_001380647   ⟸   NM_001393718
- UniProtKB: Q63681 (UniProtKB/Swiss-Prot),   O08961 (UniProtKB/Swiss-Prot),   A0A8I5ZY81 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063134404   ⟸   XM_063278334
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A1R1 (UniProtKB/TrEMBL),   A6KDA7 (UniProtKB/TrEMBL),   F1LR04 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063134398   ⟸   XM_063278328
- Peptide Label: isoform X1
- UniProtKB: Q63681 (UniProtKB/Swiss-Prot),   O08961 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063134399   ⟸   XM_063278329
- Peptide Label: isoform X2
- UniProtKB: F1LR04 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063134403   ⟸   XM_063278333
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A1R1 (UniProtKB/TrEMBL),   A6KDA7 (UniProtKB/TrEMBL),   F1LR04 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063134400   ⟸   XM_063278330
- Peptide Label: isoform X2
- UniProtKB: F1LR04 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063134402   ⟸   XM_063278332
- Peptide Label: isoform X2
- UniProtKB: F1LR04 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063134401   ⟸   XM_063278331
- Peptide Label: isoform X2
- UniProtKB: F1LR04 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000108545   ⟸   ENSRNOT00000148161
Ensembl Acc Id: ENSRNOP00000101941   ⟸   ENSRNOT00000172110
Ensembl Acc Id: ENSRNOP00000108072   ⟸   ENSRNOT00000163933
Ensembl Acc Id: ENSRNOP00000107589   ⟸   ENSRNOT00000153975
Protein Domains
C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O08961-F1-model_v2 AlphaFold O08961 1-1311 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621664 AgrOrtholog
BioCyc Gene G2FUF-6266 BioCyc
Ensembl Genes ENSRNOG00000014658 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000101895 ENTREZGENE
  ENSRNOT00000153975 ENTREZGENE
Gene3D-CATH Classic Zinc Finger UniProtKB/Swiss-Prot
InterPro Znf_C2H2_sf UniProtKB/Swiss-Prot
  Znf_C2H2_type UniProtKB/Swiss-Prot
NCBI Gene 94188 ENTREZGENE
PANTHER BLOODY FINGERS-RELATED UniProtKB/Swiss-Prot
  KRAB AND ZINC FINGER DOMAIN-CONTAINING UniProtKB/Swiss-Prot
Pfam zf-C2H2 UniProtKB/Swiss-Prot
  zf-C2H2_6 UniProtKB/Swiss-Prot
PhenoGen Zfp423 PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000014658 RatGTEx
SMART ZnF_C2H2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57667 UniProtKB/Swiss-Prot
UniProt A0A8I5ZY81 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A1R1 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LK46_RAT UniProtKB/TrEMBL
  A0ABK0LRJ1_RAT UniProtKB/TrEMBL
  A0ABK0LZQ5_RAT UniProtKB/TrEMBL
  A0ABK0M264_RAT UniProtKB/TrEMBL
  A6KDA7 ENTREZGENE, UniProtKB/TrEMBL
  A6KDA8_RAT UniProtKB/TrEMBL
  F1LR04 ENTREZGENE, UniProtKB/TrEMBL
  O08961 ENTREZGENE
  Q63681 ENTREZGENE
  ZN423_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q63681 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-11-17 Zfp423  zinc finger protein 423      Symbol and Name updated 1299863 APPROVED
2002-08-07 Roaz  Olf-1/EBF associated Zn finger protein Roaz      Symbol and Name status set to provisional 70820 PROVISIONAL