Slco1a8 (solute carrier organic anion transporter family, member 1a8) - Rat Genome Database

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Gene: Slco1a8 (solute carrier organic anion transporter family, member 1a8) Rattus norvegicus
Analyze
Symbol: Slco1a8
Name: solute carrier organic anion transporter family, member 1a8
RGD ID: 621387
Description: Enables organic anion transmembrane transporter activity. Involved in monoatomic anion transmembrane transport. Predicted to be located in plasma membrane. Predicted to be active in basolateral plasma membrane. Orthologous to human SLCO1A2 (solute carrier organic anion transporter family member 1A2); PARTICIPATES IN multispecific organic anion transporter mediated transport pathway; bile acid transport pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; cocaine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: kidney specific organic anion transporter; OAT-K1; OAT-K2; rOAT-K; rOAT-K1; rOAT-K11; rOAT-K13; rOAT-K14; rOAT-K2; rOAT-K3; rOAT-K5; rOAT-K6; rOAT-K7; rOAT-K8; rOAT-K9; Slc21a4; Slco1a3; sodium-independent organic anion transporter K1; solute carrier family 21 member 4; solute carrier organic anion transporter family member 1A3
RGD Orthologs
Mouse
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84176,706,205 - 176,749,723 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4176,706,208 - 176,745,669 (-)EnsemblGRCr8
mRatBN7.24174,975,119 - 175,018,640 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4174,975,122 - 175,014,586 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4181,270,011 - 181,313,531 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04177,054,304 - 177,097,823 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04175,674,830 - 175,718,362 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04176,255,603 - 176,299,119 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4176,255,603 - 176,295,195 (-)Ensemblrn6Rnor6.0
Rnor_5.04240,471,781 - 240,515,297 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44179,552,664 - 179,596,180 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4163,509,979 - 163,552,607 (-)NCBICelera
RGSC_v3.14179,797,787 - 179,841,302 (-)NCBI
Cytogenetic Map4q44NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Cloning and functional characterization of a new multispecific organic anion transporter, OAT-K2, in rat kidney. Masuda S, etal., Mol Pharmacol 1999 Apr;55(4):743-52.
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Cloning and functional characterization of a novel rat organic anion transporter mediating basolateral uptake of methotrexate in the kidney. Saito H, etal., J Biol Chem 1996 Aug 23;271(34):20719-25.
Additional References at PubMed
PMID:12180133   PMID:12477932  


Genomics

Comparative Map Data
Slco1a8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84176,706,205 - 176,749,723 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4176,706,208 - 176,745,669 (-)EnsemblGRCr8
mRatBN7.24174,975,119 - 175,018,640 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4174,975,122 - 175,014,586 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4181,270,011 - 181,313,531 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04177,054,304 - 177,097,823 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04175,674,830 - 175,718,362 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04176,255,603 - 176,299,119 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4176,255,603 - 176,295,195 (-)Ensemblrn6Rnor6.0
Rnor_5.04240,471,781 - 240,515,297 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44179,552,664 - 179,596,180 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4163,509,979 - 163,552,607 (-)NCBICelera
RGSC_v3.14179,797,787 - 179,841,302 (-)NCBI
Cytogenetic Map4q44NCBI
Slco1a8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396141,917,540 - 141,957,989 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6141,917,571 - 141,957,140 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm386141,971,833 - 142,012,263 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6141,971,845 - 142,011,414 (-)Ensemblmm10GRCm38
MGSCv376141,920,717 - 141,957,266 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv366141,934,602 - 141,971,151 (-)NCBIMGSCv36mm8
Celera6145,032,864 - 145,069,442 (-)NCBICelera
Cytogenetic Map6G2NCBI
cM Map673.21NCBI

Variants

.
Variants in Slco1a8
71 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:1264
Count of miRNA genes:177
Interacting mature miRNAs:203
Transcripts:ENSRNOT00000000026, ENSRNOT00000015112, ENSRNOT00000039877, ENSRNOT00000043025, ENSRNOT00000049303, ENSRNOT00000051461
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4146370897184426481Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4134095016179095016Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4146370897184426481Rat
6478757Anxrr44Anxiety related response QTL 440.01087locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4140059299181024663Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4157292416184426481Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4147299608184426481Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
6478782Anxrr52Anxiety related response QTL 520.02091locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
6478720Alc23Alcohol consumption QTL 230.00509drinking behavior trait (VT:0001422)ethanol drink intake rate to body weight ratio (CMO:0001616)4155834926184426481Rat
6478785Anxrr53Anxiety related response QTL 530.01397locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)4100752691179366077Rat
1581566Eae21Experimental allergic encephalomyelitis QTL 216.2body mass (VT:0001259)maximum body weight loss to initial body weight ratio (CMO:0001400)4137447185182447185Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4137430611182430611Rat
6478728Anxrr36Anxiety related response QTL 360.01061locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4148121375176967367Rat
6478733Anxrr37Anxiety related response QTL 370.00095locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
6478737Anxrr38Anxiety related response QTL 380.00159locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4160623982184426481Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat

Markers in Region
RH139685  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24174,975,217 - 174,975,415 (+)MAPPERmRatBN7.2
Rnor_6.04176,255,699 - 176,255,896NCBIRnor6.0
Rnor_5.04240,471,877 - 240,472,074UniSTSRnor5.0
RGSC_v3.44179,552,760 - 179,552,957UniSTSRGSC3.4
Celera4163,510,075 - 163,510,272UniSTS
RH 3.4 Map41043.4UniSTS
Cytogenetic Map4q44UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
2 7 5 28 30 38 21 10 21 1 124 20 2 23 75 31 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_030837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB012662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF445993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF445994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF445995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF445996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF445997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF445998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF445999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF446000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF446001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF446002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF446003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF446004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF446005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF446006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC085730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D79981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000000026   ⟹   ENSRNOP00000000026
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4176,706,208 - 176,745,654 (-)Ensembl
mRatBN7.2 Ensembl4174,975,122 - 175,014,571 (-)Ensembl
Rnor_6.0 Ensembl4176,255,603 - 176,295,050 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000015112   ⟹   ENSRNOP00000015112
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl4176,256,225 - 176,294,997 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000039877   ⟹   ENSRNOP00000046778
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4176,706,208 - 176,745,669 (-)Ensembl
mRatBN7.2 Ensembl4174,975,122 - 175,014,586 (-)Ensembl
Rnor_6.0 Ensembl4176,255,603 - 176,295,071 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000049303   ⟹   ENSRNOP00000047645
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl4176,256,876 - 176,295,195 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000051461   ⟹   ENSRNOP00000050159
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl4176,256,225 - 176,294,997 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107409   ⟹   ENSRNOP00000086457
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4176,706,208 - 176,745,601 (-)Ensembl
mRatBN7.2 Ensembl4174,975,122 - 175,012,873 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113317   ⟹   ENSRNOP00000090137
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4176,706,208 - 176,745,654 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000143612   ⟹   ENSRNOP00000102932
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4176,706,208 - 176,745,601 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000149874   ⟹   ENSRNOP00000099561
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4176,706,208 - 176,745,654 (-)Ensembl
RefSeq Acc Id: NM_030837   ⟹   NP_110464
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84176,706,208 - 176,749,723 (-)NCBI
mRatBN7.24174,975,122 - 175,018,640 (-)NCBI
Rnor_6.04176,255,603 - 176,299,119 (-)NCBI
Rnor_5.04240,471,781 - 240,515,297 (-)NCBI
RGSC_v3.44179,552,664 - 179,596,180 (-)RGD
Celera4163,509,979 - 163,552,607 (-)RGD
Sequence:
RefSeq Acc Id: XM_039108402   ⟹   XP_038964330
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84176,706,205 - 176,747,125 (-)NCBI
mRatBN7.24174,975,128 - 175,015,574 (-)NCBI
RefSeq Acc Id: XM_039108403   ⟹   XP_038964331
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84176,706,205 - 176,747,125 (-)NCBI
mRatBN7.24174,975,128 - 175,015,574 (-)NCBI
RefSeq Acc Id: XM_039108405   ⟹   XP_038964333
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84176,706,205 - 176,747,125 (-)NCBI
mRatBN7.24174,975,128 - 175,015,574 (-)NCBI
RefSeq Acc Id: XM_039108406   ⟹   XP_038964334
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84176,706,205 - 176,747,125 (-)NCBI
mRatBN7.24174,975,128 - 175,015,574 (-)NCBI
RefSeq Acc Id: XM_039108409   ⟹   XP_038964337
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84176,706,205 - 176,747,125 (-)NCBI
mRatBN7.24174,975,128 - 175,015,574 (-)NCBI
RefSeq Acc Id: XM_063286728   ⟹   XP_063142798
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84176,706,205 - 176,747,125 (-)NCBI
RefSeq Acc Id: XM_063286729   ⟹   XP_063142799
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84176,706,205 - 176,747,125 (-)NCBI
RefSeq Acc Id: XM_063286730   ⟹   XP_063142800
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84176,706,205 - 176,747,125 (-)NCBI
Protein Sequences
Protein RefSeqs NP_110464 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964330 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964331 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964333 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964334 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964337 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142798 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142799 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142800 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH85730 (Get FASTA)   NCBI Sequence Viewer  
  AAL84221 (Get FASTA)   NCBI Sequence Viewer  
  AAL84222 (Get FASTA)   NCBI Sequence Viewer  
  AAL84223 (Get FASTA)   NCBI Sequence Viewer  
  AAL84224 (Get FASTA)   NCBI Sequence Viewer  
  AAL84225 (Get FASTA)   NCBI Sequence Viewer  
  AAL84226 (Get FASTA)   NCBI Sequence Viewer  
  AAL84227 (Get FASTA)   NCBI Sequence Viewer  
  AAL84228 (Get FASTA)   NCBI Sequence Viewer  
  AAL84229 (Get FASTA)   NCBI Sequence Viewer  
  AAL84230 (Get FASTA)   NCBI Sequence Viewer  
  AAL84231 (Get FASTA)   NCBI Sequence Viewer  
  AAL84232 (Get FASTA)   NCBI Sequence Viewer  
  AAL84233 (Get FASTA)   NCBI Sequence Viewer  
  AAL84234 (Get FASTA)   NCBI Sequence Viewer  
  BAA11476 (Get FASTA)   NCBI Sequence Viewer  
  BAA77793 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000000026
  ENSRNOP00000000026.5
  ENSRNOP00000086457
  ENSRNOP00000090137
  ENSRNOP00000099561
  ENSRNOP00000102932
GenBank Protein P70502 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_110464   ⟸   NM_030837
- UniProtKB: A6IMQ2 (UniProtKB/TrEMBL),   A0A0A0MXT4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000000026   ⟸   ENSRNOT00000000026
Ensembl Acc Id: ENSRNOP00000050159   ⟸   ENSRNOT00000051461
Ensembl Acc Id: ENSRNOP00000046778   ⟸   ENSRNOT00000039877
Ensembl Acc Id: ENSRNOP00000047645   ⟸   ENSRNOT00000049303
Ensembl Acc Id: ENSRNOP00000015112   ⟸   ENSRNOT00000015112
RefSeq Acc Id: XP_038964337   ⟸   XM_039108409
- Peptide Label: isoform X8
- UniProtKB: A6IMQ4 (UniProtKB/TrEMBL),   A6IMR9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038964333   ⟸   XM_039108405
- Peptide Label: isoform X5
- UniProtKB: A6IMQ6 (UniProtKB/TrEMBL),   A6IMS1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038964334   ⟸   XM_039108406
- Peptide Label: isoform X6
- UniProtKB: A6IMR1 (UniProtKB/TrEMBL),   A6IMR5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038964331   ⟸   XM_039108403
- Peptide Label: isoform X3
- UniProtKB: A6IMR2 (UniProtKB/TrEMBL),   A6IMR6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038964330   ⟸   XM_039108402
- Peptide Label: isoform X2
- UniProtKB: A6IMQ0 (UniProtKB/TrEMBL),   A6IMR5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000086457   ⟸   ENSRNOT00000107409
RefSeq Acc Id: XP_063142800   ⟸   XM_063286730
- Peptide Label: isoform X7
- UniProtKB: A6IMR9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142799   ⟸   XM_063286729
- Peptide Label: isoform X4
- UniProtKB: A6IMS3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142798   ⟸   XM_063286728
- Peptide Label: isoform X1
- UniProtKB: A6IMQ2 (UniProtKB/TrEMBL),   A0A0A0MXT4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000102932   ⟸   ENSRNOT00000143612
Ensembl Acc Id: ENSRNOP00000099561   ⟸   ENSRNOT00000149874
Ensembl Acc Id: ENSRNOP00000090137   ⟸   ENSRNOT00000113317
Protein Domains
Kazal-like   Major facilitator superfamily (MFS) profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P70502-F1-model_v2 AlphaFold P70502 1-670 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693496
Promoter ID:EPDNEW_R4006
Type:multiple initiation site
Name:Slc21a4_1
Description:kidney specific organic anion transporter
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04176,295,008 - 176,295,068EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621387 AgrOrtholog
BioCyc Gene G2FUF-42502 BioCyc
Ensembl Genes ENSRNOG00000010388 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000000026 ENTREZGENE
  ENSRNOT00000000026.7 UniProtKB/Swiss-Prot
  ENSRNOT00000107409 ENTREZGENE
  ENSRNOT00000113317 ENTREZGENE
  ENSRNOT00000143612 ENTREZGENE
  ENSRNOT00000149874 ENTREZGENE
Gene3D-CATH 1.20.1250.20 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7110926 IMAGE-MGC_LOAD
InterPro Kazal_dom UniProtKB/Swiss-Prot
  Kazal_dom_sf UniProtKB/Swiss-Prot
  MFS_trans_sf UniProtKB/Swiss-Prot
  OATP UniProtKB/Swiss-Prot
KEGG Report rno:80899 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93404 IMAGE-MGC_LOAD
NCBI Gene 80899 ENTREZGENE
PANTHER PTHR11388 UniProtKB/Swiss-Prot
  SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1A2 UniProtKB/Swiss-Prot
Pfam Kazal_2 UniProtKB/Swiss-Prot
  OATP UniProtKB/Swiss-Prot
PhenoGen Slco1a8 PhenoGen
PROSITE KAZAL_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000010388 RatGTEx
Superfamily-SCOP SSF100895 UniProtKB/Swiss-Prot
  SSF103473 UniProtKB/Swiss-Prot
UniProt A0A0A0MXT4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A8V7_RAT UniProtKB/TrEMBL
  A6IMQ0 ENTREZGENE, UniProtKB/TrEMBL
  A6IMQ2 ENTREZGENE, UniProtKB/TrEMBL
  A6IMQ4 ENTREZGENE, UniProtKB/TrEMBL
  A6IMQ6 ENTREZGENE, UniProtKB/TrEMBL
  A6IMR1 ENTREZGENE, UniProtKB/TrEMBL
  A6IMR2 ENTREZGENE, UniProtKB/TrEMBL
  A6IMR5 ENTREZGENE, UniProtKB/TrEMBL
  A6IMR6 ENTREZGENE, UniProtKB/TrEMBL
  A6IMR9 ENTREZGENE, UniProtKB/TrEMBL
  A6IMS1 ENTREZGENE, UniProtKB/TrEMBL
  A6IMS3 ENTREZGENE, UniProtKB/TrEMBL
  P70502 ENTREZGENE
  Q5U341_RAT UniProtKB/TrEMBL
  SO1A3_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q8R008 UniProtKB/Swiss-Prot
  Q8R4J0 UniProtKB/Swiss-Prot
  Q8R4J1 UniProtKB/Swiss-Prot
  Q8R4J2 UniProtKB/Swiss-Prot
  Q8R4J3 UniProtKB/Swiss-Prot
  Q8R4J4 UniProtKB/Swiss-Prot
  Q8R4J5 UniProtKB/Swiss-Prot
  Q8R4J6 UniProtKB/Swiss-Prot
  Q8R4J7 UniProtKB/Swiss-Prot
  Q8R4J8 UniProtKB/Swiss-Prot
  Q8R4J9 UniProtKB/Swiss-Prot
  Q8R4K0 UniProtKB/Swiss-Prot
  Q8R4K1 UniProtKB/Swiss-Prot
  Q9WTM0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-05-14 Slco1a8  solute carrier organic anion transporter family, member 1a8  Slco1a3  solute carrier organic anion transporter family member 1A3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2020-05-14 Slco1a3  solute carrier organic anion transporter family member 1A3  Slc21a4  kidney specific organic anion transporter  Name and Symbol changed 629549 APPROVED
2002-08-07 Slc21a4  kidney specific organic anion transporter      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to the basolateral membrane in renal tubules 729732