Myo5b (myosin Vb) - Rat Genome Database

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Gene: Myo5b (myosin Vb) Rattus norvegicus
Analyze
Symbol: Myo5b
Name: myosin Vb
RGD ID: 621347
Description: Enables ATP hydrolysis activity; ionotropic glutamate receptor binding activity; and small GTPase binding activity. Involved in several processes, including cellular response to glycine; endosomal transport; and positive regulation of neurogenesis. Located in several cellular components, including dendritic spine; neuronal cell body; and recycling endosome. Is active in several cellular components, including Schaffer collateral - CA1 synapse; postsynaptic actin cytoskeleton; and postsynaptic recycling endosome membrane. Human ortholog(s) of this gene implicated in microvillus inclusion disease and progressive familial intrahepatic cholestasis. Orthologous to human MYO5B (myosin VB); PARTICIPATES IN vasopressin signaling pathway; insulin responsive facilitative sugar transporter mediated glucose transport pathway; vasopressin signaling pathway via receptor type 2; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: myosin 5B; myosin heavy chain myr 6; Myosin of the dilute-myosin-V family; myosin-Vb; Myr6; unconventional myosin-Vb
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81870,313,717 - 70,613,918 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1870,311,990 - 70,613,918 (+)EnsemblGRCr8
mRatBN7.21868,038,759 - 68,341,568 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1868,038,759 - 68,338,745 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1870,146,914 - 70,446,818 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01870,812,463 - 71,116,126 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01868,671,318 - 68,972,854 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01870,426,865 - 70,729,985 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1870,427,007 - 70,729,030 (+)Ensemblrn6Rnor6.0
Rnor_5.01869,568,169 - 69,869,070 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41871,381,068 - 71,580,824 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1866,217,242 - 66,515,213 (+)NCBICelera
RGSC_v3.11871,454,267 - 71,654,025 (+)NCBI
Cytogenetic Map18q12.2NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(1->4)-beta-D-glucan  (ISO)
(S)-nicotine  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,6-dimethoxyphenol  (ISO)
2,6-dinitrotoluene  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
entinostat  (ISO)
enzyme inhibitor  (ISO)
ethanol  (EXP,ISO)
folic acid  (ISO)
furfural  (ISO)
gentamycin  (EXP)
glyphosate  (EXP)
GSK-J4  (ISO)
haloperidol  (ISO)
inulin  (ISO)
kainic acid  (ISO)
methamphetamine  (ISO)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
nicotine  (ISO)
okadaic acid  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
pirinixic acid  (EXP,ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
Soman  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Physiology and pathophysiology of the vasopressin-regulated renal water reabsorption. Boone M and Deen PM, Pflugers Arch. 2008 Sep;456(6):1005-24. Epub 2008 Apr 23.
2. Requirement of myosin Vb.Rab11a.Rab11-FIP2 complex in cholesterol-regulated translocation of NPC1L1 to the cell surface. Chu BB, etal., J Biol Chem. 2009 Aug 14;284(33):22481-90. doi: 10.1074/jbc.M109.034355. Epub 2009 Jun 19.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Muscle cells engage Rab8A and myosin Vb in insulin-dependent GLUT4 translocation. Ishikura S and Klip A, Am J Physiol Cell Physiol. 2008 Oct;295(4):C1016-25. Epub 2008 Aug 13.
5. BDNF regulates Rab11-mediated recycling endosome dynamics to induce dendritic branching. Lazo OM, etal., J Neurosci. 2013 Apr 3;33(14):6112-22. doi: 10.1523/JNEUROSCI.4630-12.2013.
6. Involvement of myosin Vb in glutamate receptor trafficking. Lise MF, etal., J Biol Chem. 2006 Feb 10;281(6):3669-78. Epub 2005 Dec 7.
7. Myosin Vb controls biogenesis of post-Golgi Rab10 carriers during axon development. Liu Y, etal., Nat Commun. 2013;4:2005. doi: 10.1038/ncomms3005.
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. A Role of myosin Vb and Rab11-FIP2 in the aquaporin-2 shuttle. Nedvetsky PI, etal., Traffic. 2007 Feb;8(2):110-23. Epub 2006 Dec 6.
10. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
11. Chemical-genetic inhibition of a sensitized mutant myosin Vb demonstrates a role in peripheral-pericentriolar membrane traffic. Provance DW, etal., Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):1868-73. Epub 2004 Feb 6.
12. GOA pipeline RGD automated data pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Rho GTPases in insulin-stimulated glucose uptake. Satoh T Small GTPases. 2014;5:e28102. doi: 10.4161/sgtp.28102. Epub 2014 Mar 10.
16. Role for myosin-V motor proteins in the selective delivery of Kv channel isoforms to the membrane surface of cardiac myocytes. Schumacher-Bass SM, etal., Circ Res. 2014 Mar 14;114(6):982-92. doi: 10.1161/CIRCRESAHA.114.302711. Epub 2014 Feb 7.
17. MST3 kinase phosphorylates TAO1/2 to enable Myosin Va function in promoting spine synapse development. Ultanir SK, etal., Neuron. 2014 Dec 3;84(5):968-82. doi: 10.1016/j.neuron.2014.10.025. Epub 2014 Nov 13.
18. Myosin Vb mobilizes recycling endosomes and AMPA receptors for postsynaptic plasticity. Wang Z, etal., Cell. 2008 Oct 31;135(3):535-48. doi: 10.1016/j.cell.2008.09.057.
19. Cloning and characterization of myr 6, an unconventional myosin of the dilute/myosin-V family. Zhao LP, etal., Proc Natl Acad Sci U S A 1996 Oct 1;93(20):10826-31.
Additional References at PubMed
PMID:17462998   PMID:17507647   PMID:19056867   PMID:20124353   PMID:21206382   PMID:22114352   PMID:23389633   PMID:30545898  


Genomics

Comparative Map Data
Myo5b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81870,313,717 - 70,613,918 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1870,311,990 - 70,613,918 (+)EnsemblGRCr8
mRatBN7.21868,038,759 - 68,341,568 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1868,038,759 - 68,338,745 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1870,146,914 - 70,446,818 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01870,812,463 - 71,116,126 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01868,671,318 - 68,972,854 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01870,426,865 - 70,729,985 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1870,427,007 - 70,729,030 (+)Ensemblrn6Rnor6.0
Rnor_5.01869,568,169 - 69,869,070 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41871,381,068 - 71,580,824 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1866,217,242 - 66,515,213 (+)NCBICelera
RGSC_v3.11871,454,267 - 71,654,025 (+)NCBI
Cytogenetic Map18q12.2NCBI
MYO5B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381849,822,789 - 50,195,147 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1849,822,789 - 50,195,164 (-)Ensemblhg38GRCh38
GRCh371847,349,159 - 47,721,517 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361845,603,099 - 45,975,382 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341845,603,183 - 45,975,176NCBI
Celera1844,205,823 - 44,578,011 (-)NCBICelera
Cytogenetic Map18q21.1NCBI
HuRef1844,203,440 - 44,575,850 (-)NCBIHuRef
CHM1_11847,344,771 - 47,717,073 (-)NCBICHM1_1
T2T-CHM13v2.01850,024,565 - 50,396,878 (-)NCBIT2T-CHM13v2.0
Myo5b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391874,575,435 - 74,905,769 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1874,574,007 - 74,904,564 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381874,442,364 - 74,772,698 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1874,440,936 - 74,771,493 (+)Ensemblmm10GRCm38
MGSCv371874,602,273 - 74,931,131 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361874,567,984 - 74,896,170 (+)NCBIMGSCv36mm8
Celera1875,677,935 - 75,995,786 (+)NCBICelera
Cytogenetic Map18E2NCBI
cM Map1850.7NCBI
Myo5b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540234,892,652 - 35,143,704 (-)Ensembl
ChiLan1.0NW_00495540234,892,652 - 35,247,431 (-)NCBIChiLan1.0ChiLan1.0
MYO5B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21767,353,649 - 67,723,298 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11853,046,252 - 53,415,901 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01843,207,387 - 43,575,951 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11846,551,603 - 46,783,739 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1846,555,259 - 46,786,223 (-)EnsemblpanPan2panpan1.1
MYO5B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1778,671,636 - 79,006,010 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl778,671,616 - 79,006,006 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha778,076,067 - 78,407,834 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0778,734,540 - 79,067,184 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl778,734,614 - 79,067,103 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1778,448,208 - 78,782,608 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0778,479,066 - 78,811,670 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0778,763,776 - 79,096,706 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Myo5b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494437,781,039 - 37,998,722 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649712,932,789 - 13,234,244 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493649712,932,367 - 13,236,916 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYO5B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl199,418,449 - 99,810,139 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1199,418,242 - 99,810,934 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21109,021,575 - 109,119,992 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MYO5B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11830,759,345 - 31,143,139 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1830,759,764 - 31,143,474 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660504,906,479 - 5,290,645 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myo5b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477813,347,705 - 13,740,767 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462477813,352,285 - 13,740,621 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Myo5b
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11557,226,779 - 57,524,577 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Myo5b
1408 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:264
Count of miRNA genes:170
Interacting mature miRNAs:194
Transcripts:ENSRNOT00000019512
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182507112683910656Rat
1331730Scl27Serum cholesterol level QTL 273.826blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)185449080186134022Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182349405785487725Rat
1331742Bp228Blood pressure QTL 2283.88752arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050577371277Rat
1298072Cia26Collagen induced arthritis QTL 263.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)186438376279484311Rat
631834Sach3Saccharin preference QTL 33.90.01consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)183857591983575919Rat
12904668Bw188Body weight QTL 1880.03body mass (VT:0001259)body weight (CMO:0000012)182682218671822186Rat
12904669Cm125Cardiac mass QTL 1250.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)182682218671822186Rat
6893683Bw110Body weight QTL 1102.70.002body mass (VT:0001259)body weight (CMO:0000012)184562030686134022Rat
12904670Cm126Cardiac mass QTL 1260.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)182682218671822186Rat
7794793Mcs34Mammary carcinoma susceptibility QTL 341.54mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)186563556785897775Rat
12904677Kidm72Kidney mass QTL 720.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)182682218671822186Rat
9589041Epfw12Epididymal fat weight QTL 1217.080.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)184891573786134022Rat
8694432Bw165Body weight QTL 1653.810.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)184891573786134022Rat
12904673Cm127Cardiac mass QTL 1270.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)182682218671822186Rat
12904675Am19Aortic mass QTL 190.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)182682218671822186Rat
1331774Bp226Blood pressure QTL 2264.41065arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050577371277Rat
9589816Gluco68Glucose level QTL 687.250.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)183199089176990891Rat
1331770Bp234Blood pressure QTL 2343.807arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)184562030686134022Rat
2301969Bp324Blood pressure QTL 3244.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)186198220476619168Rat
2303120Mamtr8Mammary tumor resistance QTL 80.001mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)183161050585493247Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181206648285493247Rat
12880368Bw187Body weight QTL 1870.045body mass (VT:0001259)body weight (CMO:0000012)183337915878379158Rat
724542Kidm2Kidney mass QTL 22.6kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)186144685386134022Rat
61367Iddm4Insulin dependent diabetes mellitus QTL 42.330.0074blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)184046238385462383Rat
1359020Ppulsi2Prepulse inhibition QTL 22.71prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)185449080176272247Rat
2312600Bp341Blood pressure QTL 3410.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)186160038472538878Rat
9590318Scort22Serum corticosterone level QTL 227.640.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)183199089176990891Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181206648285493247Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181564228086134022Rat
12904069Cm123Cardiac mass QTL 1230.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)183337915878379158Rat
1331798Bp224Blood pressure QTL 2243.53873arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050577371277Rat
12904070Cm124Cardiac mass QTL 1240.01heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)183337915878379158Rat
2303584Gluco55Glucose level QTL 552blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)185079521286134022Rat
12904071Am18Aortic mass QTL 180.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)183337915878379158Rat
2301413Bp318Blood pressure QTL 3180.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182682218671822186Rat
61383Bp47Blood pressure QTL 4717.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)183152278376522783Rat
12904067Cm122Cardiac mass QTL 1220.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)183337915878379158Rat
61384Bp48Blood pressure QTL 4819.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)186289225779484461Rat
2301417Bp319Blood pressure QTL 3190.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183337915878379158Rat
12904073Kidm71Kidney mass QTL 710.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)183337915878379158Rat
738008Hcar14Hepatocarcinoma resistance QTL 144.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion number (CMO:0001462)185782524385493247Rat
1331776Bp225Blood pressure QTL 2252.829arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)183161050577371277Rat
631518Bw11Body weight QTL 112.8body mass (VT:0001259)body weight (CMO:0000012)183612162681121626Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)183199089176990891Rat
8694366Abfw8Abdominal fat weight QTL 86.380.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)184891573786134022Rat
631509Sald2Serum aldosterone level QTL 22.9blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)182641582171415821Rat
631274Sprol1Serum protein level QTL 15.3blood total protein amount (VT:0005567)serum total protein level (CMO:0000661)183164450879484311Rat
1358193Emca2Estrogen-induced mammary cancer QTL 21.6mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)186584644786134022Rat
1598832Glom11Glomerulus QTL 112.9kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)185326667186134022Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181955353285493247Rat
8694378Bw157Body weight QTL 1573.590.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)183199089176990891Rat
2303571Bw92Body weight QTL 923body mass (VT:0001259)body weight (CMO:0000012)185079521286134022Rat
631675Iddm15Insulin dependent diabetes mellitus QTL 15urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)186289225779484461Rat
61429Cia17Collagen induced arthritis QTL 174.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)183161050572538878Rat

Markers in Region
D18Rat10  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81870,333,871 - 70,334,028 (+)Marker Load Pipeline
mRatBN7.21868,058,657 - 68,058,814 (+)MAPPERmRatBN7.2
Rnor_6.01870,446,814 - 70,446,970NCBIRnor6.0
Rnor_5.01869,587,777 - 69,587,933UniSTSRnor5.0
RGSC_v3.41871,265,847 - 71,266,175RGDRGSC3.4
RGSC_v3.41871,265,925 - 71,266,081UniSTSRGSC3.4
Celera1866,236,361 - 66,236,517UniSTS
RGSC_v3.11871,339,126 - 71,339,282RGD
RH 3.4 Map18686.9UniSTS
RH 3.4 Map18686.9RGD
RH 2.0 Map18242.1RGD
SHRSP x BN Map1842.1199RGD
Cytogenetic Map18q12.2-q12.3UniSTS
BF403782  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21868,313,892 - 68,313,994 (+)MAPPERmRatBN7.2
Rnor_6.01870,702,613 - 70,702,714NCBIRnor6.0
Rnor_5.01869,842,127 - 69,842,228UniSTSRnor5.0
RGSC_v3.41871,556,004 - 71,556,105UniSTSRGSC3.4
Celera1866,490,362 - 66,490,463UniSTS
RH 3.4 Map18689.2UniSTS
Cytogenetic Map18q12.2-q12.3UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 11 64 161 91 90 59 66 59 6 342 162 11 140 97 93 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_017083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600852 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039096575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039096576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U60416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000019512   ⟹   ENSRNOP00000019512
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1870,313,976 - 70,613,918 (+)Ensembl
mRatBN7.2 Ensembl1868,038,759 - 68,338,745 (+)Ensembl
Rnor_6.0 Ensembl1870,427,103 - 70,727,462 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000085318   ⟹   ENSRNOP00000069482
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1870,435,262 - 70,606,832 (+)Ensembl
mRatBN7.2 Ensembl1868,159,911 - 68,331,659 (+)Ensembl
Rnor_6.0 Ensembl1870,548,607 - 70,727,092 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000087959   ⟹   ENSRNOP00000072468
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1870,313,976 - 70,613,918 (+)Ensembl
mRatBN7.2 Ensembl1868,038,759 - 68,338,745 (+)Ensembl
Rnor_6.0 Ensembl1870,427,007 - 70,729,030 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000094389   ⟹   ENSRNOP00000081367
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1870,400,448 - 70,613,915 (+)Ensembl
mRatBN7.2 Ensembl1868,125,244 - 68,338,745 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096247   ⟹   ENSRNOP00000079126
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1870,311,990 - 70,613,915 (+)Ensembl
mRatBN7.2 Ensembl1868,038,759 - 68,338,745 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117025   ⟹   ENSRNOP00000091793
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1870,420,077 - 70,613,915 (+)Ensembl
mRatBN7.2 Ensembl1868,144,771 - 68,338,745 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000138842   ⟹   ENSRNOP00000110049
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1870,435,109 - 70,606,832 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000154755   ⟹   ENSRNOP00000105443
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1870,312,181 - 70,613,915 (+)Ensembl
RefSeq Acc Id: NM_017083   ⟹   NP_058779
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,313,976 - 70,613,918 (+)NCBI
mRatBN7.21868,038,759 - 68,338,745 (+)NCBI
Rnor_6.01870,427,103 - 70,727,462 (+)NCBI
Rnor_5.01869,568,169 - 69,869,070 (+)NCBI
RGSC_v3.41871,381,068 - 71,580,824 (+)RGD
Celera1866,217,242 - 66,515,213 (+)RGD
Sequence:
RefSeq Acc Id: XM_006254908   ⟹   XP_006254970
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,478,386 - 70,613,918 (+)NCBI
mRatBN7.21868,203,112 - 68,341,568 (+)NCBI
Rnor_6.01870,591,613 - 70,729,985 (+)NCBI
Rnor_5.01869,568,169 - 69,869,070 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008772085   ⟹   XP_008770307
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,400,405 - 70,613,918 (+)NCBI
mRatBN7.21868,125,211 - 68,341,568 (+)NCBI
Rnor_6.01870,513,791 - 70,729,985 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008772086   ⟹   XP_008770308
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,400,405 - 70,613,918 (+)NCBI
mRatBN7.21868,125,211 - 68,338,375 (+)NCBI
Rnor_6.01870,513,791 - 70,729,985 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600852   ⟹   XP_017456341
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,400,405 - 70,613,918 (+)NCBI
mRatBN7.21868,125,211 - 68,341,568 (+)NCBI
Rnor_6.01870,513,791 - 70,729,985 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600854   ⟹   XP_017456343
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,432,325 - 70,613,918 (+)NCBI
mRatBN7.21868,157,158 - 68,338,375 (+)NCBI
Rnor_6.01870,545,760 - 70,729,985 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600855   ⟹   XP_017456344
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,400,405 - 70,613,918 (+)NCBI
mRatBN7.21868,125,211 - 68,341,568 (+)NCBI
Rnor_6.01870,513,791 - 70,729,985 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039096575   ⟹   XP_038952503
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,400,405 - 70,613,918 (+)NCBI
mRatBN7.21868,125,211 - 68,341,568 (+)NCBI
RefSeq Acc Id: XM_039096576   ⟹   XP_038952504
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,544,183 - 70,613,918 (+)NCBI
mRatBN7.21868,264,441 - 68,341,568 (+)NCBI
RefSeq Acc Id: XM_063277098   ⟹   XP_063133168
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,400,405 - 70,613,918 (+)NCBI
RefSeq Acc Id: XM_063277099   ⟹   XP_063133169
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,400,212 - 70,613,918 (+)NCBI
RefSeq Acc Id: XM_063277100   ⟹   XP_063133170
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,313,717 - 70,613,918 (+)NCBI
RefSeq Acc Id: XM_063277101   ⟹   XP_063133171
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,400,405 - 70,613,918 (+)NCBI
RefSeq Acc Id: XM_063277102   ⟹   XP_063133172
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,400,405 - 70,613,918 (+)NCBI
RefSeq Acc Id: XM_063277103   ⟹   XP_063133173
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,400,405 - 70,613,918 (+)NCBI
RefSeq Acc Id: XM_063277104   ⟹   XP_063133174
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,400,420 - 70,613,918 (+)NCBI
RefSeq Acc Id: XM_063277105   ⟹   XP_063133175
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,410,329 - 70,613,918 (+)NCBI
RefSeq Acc Id: NP_058779   ⟸   NM_017083
- UniProtKB: F1M3R4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254970   ⟸   XM_006254908
- Peptide Label: isoform X14
- UniProtKB: F1M3R4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770307   ⟸   XM_008772085
- Peptide Label: isoform X1
- UniProtKB: F1M3R4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770308   ⟸   XM_008772086
- Peptide Label: isoform X7
- UniProtKB: A0A8I6ACS1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456344   ⟸   XM_017600855
- Peptide Label: isoform X6
- UniProtKB: A0A8I5ZST3 (UniProtKB/TrEMBL),   A0A8I6ACS1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456341   ⟸   XM_017600852
- Peptide Label: isoform X2
- UniProtKB: F1M3R4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456343   ⟸   XM_017600854
- Peptide Label: isoform X3
- UniProtKB: F1M3R4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069482   ⟸   ENSRNOT00000085318
Ensembl Acc Id: ENSRNOP00000072468   ⟸   ENSRNOT00000087959
Ensembl Acc Id: ENSRNOP00000019512   ⟸   ENSRNOT00000019512
RefSeq Acc Id: XP_038952503   ⟸   XM_039096575
- Peptide Label: isoform X10
- UniProtKB: A0A8I6G4V2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038952504   ⟸   XM_039096576
- Peptide Label: isoform X15
- UniProtKB: A6KRF7 (UniProtKB/TrEMBL),   A6KRF8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000079126   ⟸   ENSRNOT00000096247
Ensembl Acc Id: ENSRNOP00000081367   ⟸   ENSRNOT00000094389
Ensembl Acc Id: ENSRNOP00000091793   ⟸   ENSRNOT00000117025
RefSeq Acc Id: XP_063133170   ⟸   XM_063277100
- Peptide Label: isoform X8
- UniProtKB: A0A0G2K318 (UniProtKB/TrEMBL),   F1M3R4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133169   ⟸   XM_063277099
- Peptide Label: isoform X5
- UniProtKB: F1M3R4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133168   ⟸   XM_063277098
- Peptide Label: isoform X4
- UniProtKB: F1M3R4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133172   ⟸   XM_063277102
- Peptide Label: isoform X11
- UniProtKB: A0A8I6G4V2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133171   ⟸   XM_063277101
- Peptide Label: isoform X9
- UniProtKB: A0A8I6ACS1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133173   ⟸   XM_063277103
- Peptide Label: isoform X12
- UniProtKB: A0A8I6G4V2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133174   ⟸   XM_063277104
- Peptide Label: isoform X13
- UniProtKB: F1M3R4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133175   ⟸   XM_063277105
- Peptide Label: isoform X13
- UniProtKB: F1M3R4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000105443   ⟸   ENSRNOT00000154755
Ensembl Acc Id: ENSRNOP00000110049   ⟸   ENSRNOT00000138842
Protein Domains
Dilute   IQ   Myosin motor   Myosin N-terminal SH3-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P70569-F1-model_v2 AlphaFold P70569 1-1846 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700866
Promoter ID:EPDNEW_R11389
Type:initiation region
Name:Myo5b_1
Description:myosin Vb
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01870,427,065 - 70,427,125EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621347 AgrOrtholog
BioCyc Gene G2FUF-7025 BioCyc
Ensembl Genes ENSRNOG00000014104 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000019512 ENTREZGENE
  ENSRNOT00000085318 ENTREZGENE
  ENSRNOT00000094389 ENTREZGENE
  ENSRNOT00000154755 ENTREZGENE
Gene3D-CATH 1.10.10.820 UniProtKB/Swiss-Prot
  1.20.5.190 UniProtKB/Swiss-Prot
  1.20.58.530 UniProtKB/Swiss-Prot
  3.40.850.10 UniProtKB/Swiss-Prot
  6.20.240.20 UniProtKB/Swiss-Prot
  Myosin VI head, motor domain, U50 subdomain UniProtKB/Swiss-Prot
InterPro Dilute_dom UniProtKB/Swiss-Prot
  IQ_motif_EF-hand-BS UniProtKB/Swiss-Prot
  Kinesin_motor_dom_sf UniProtKB/Swiss-Prot
  Myo5b_CBD UniProtKB/Swiss-Prot
  Myosin_head_motor_dom UniProtKB/Swiss-Prot
  Myosin_N UniProtKB/Swiss-Prot
  MYSc_Myo5 UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
KEGG Report rno:25132 UniProtKB/Swiss-Prot
NCBI Gene 25132 ENTREZGENE
PANTHER MYOSIN UniProtKB/Swiss-Prot
  UNCONVENTIONAL MYOSIN-VB UniProtKB/Swiss-Prot
Pfam DIL UniProtKB/Swiss-Prot
  Myosin_head UniProtKB/Swiss-Prot
  PF00612 UniProtKB/Swiss-Prot
PhenoGen Myo5b PhenoGen
PRINTS MYOSINHEAVY UniProtKB/Swiss-Prot
PROSITE DILUTE UniProtKB/Swiss-Prot
  MYOSIN_MOTOR UniProtKB/Swiss-Prot
  PS50096 UniProtKB/Swiss-Prot
  SH3_LIKE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000014104 RatGTEx
SMART DIL UniProtKB/Swiss-Prot
  MYSc UniProtKB/Swiss-Prot
  SM00015 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt A0A0G2JVH1_RAT UniProtKB/TrEMBL
  A0A0G2K318 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZST3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ACS1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G4V2 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L669_RAT UniProtKB/TrEMBL
  A0ABK0LV10_RAT UniProtKB/TrEMBL
  A6KRF7 ENTREZGENE, UniProtKB/TrEMBL
  A6KRF8 ENTREZGENE, UniProtKB/TrEMBL
  A6KRF9_RAT UniProtKB/TrEMBL
  F1M3R4 ENTREZGENE, UniProtKB/TrEMBL
  MYO5B_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-05-27 Myo5b  myosin Vb  Myo5b  myosin 5B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2003-04-09 Myo5b  myosin 5B      Symbol and Name updated 629477 APPROVED
2003-03-06 Myo5b  myosin 5B  Myr6  Myosin of the dilute-myosin-V family  Data merged from RGD:3147 628472 PROVISIONAL
2002-08-07 Myo5b        Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Myr6  Myosin of the dilute-myosin-V family      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in brain, highest expression in choroid plexus and the limbic system, 633433