Hes3 (hes family bHLH transcription factor 3) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Hes3 (hes family bHLH transcription factor 3) Rattus norvegicus
Analyze
Symbol: Hes3
Name: hes family bHLH transcription factor 3
RGD ID: 621339
Description: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of DNA-templated transcription. Predicted to be active in nucleus. Orthologous to human HES3 (hes family bHLH transcription factor 3); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 6-propyl-2-thiouracil; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: hairy and enhancer of split 3; hairy and enhancer of split 3 (Drosophila); transcription factor HES-3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85168,076,337 - 168,082,270 (-)NCBIGRCr8
mRatBN7.25162,793,611 - 162,799,578 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5162,794,367 - 162,796,261 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5165,497,390 - 165,499,284 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05167,318,992 - 167,320,886 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05167,281,192 - 167,283,086 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05169,463,196 - 169,469,795 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5169,464,989 - 169,467,153 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05173,017,857 - 173,020,507 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45169,516,965 - 169,518,859 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15169,527,152 - 169,529,047 (-)NCBI
Celera5161,025,648 - 161,027,542 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA,IEA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split. Sasai Y, etal., Genes Dev 1992 Dec;6(12B):2620-34.
Additional References at PubMed
PMID:10858455   PMID:11500373   PMID:11522634   PMID:19050759  


Genomics

Comparative Map Data
Hes3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85168,076,337 - 168,082,270 (-)NCBIGRCr8
mRatBN7.25162,793,611 - 162,799,578 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5162,794,367 - 162,796,261 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5165,497,390 - 165,499,284 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05167,318,992 - 167,320,886 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05167,281,192 - 167,283,086 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05169,463,196 - 169,469,795 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5169,464,989 - 169,467,153 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05173,017,857 - 173,020,507 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45169,516,965 - 169,518,859 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15169,527,152 - 169,529,047 (-)NCBI
Celera5161,025,648 - 161,027,542 (-)NCBICelera
Cytogenetic Map5q36NCBI
HES3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3816,244,179 - 6,245,578 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl16,244,179 - 6,245,578 (+)EnsemblGRCh38hg38GRCh38
GRCh3716,304,239 - 6,305,638 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3616,226,849 - 6,228,225 (+)NCBINCBI36Build 36hg18NCBI36
Celera15,418,756 - 5,420,142 (+)NCBICelera
Cytogenetic Map1p36.31NCBI
HuRef15,452,365 - 5,454,401 (+)NCBIHuRef
CHM1_116,292,896 - 6,294,282 (+)NCBICHM1_1
T2T-CHM13v2.015,769,823 - 5,771,222 (+)NCBIT2T-CHM13v2.0
Hes3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394152,369,707 - 152,376,133 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4152,370,429 - 152,376,119 (-)EnsemblGRCm39 Ensembl
GRCm384152,285,250 - 152,291,911 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4152,285,972 - 152,291,662 (-)EnsemblGRCm38mm10GRCm38
MGSCv374151,660,081 - 151,665,771 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364151,129,772 - 151,135,462 (-)NCBIMGSCv36mm8
Celera4154,572,853 - 154,579,001 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map483.01NCBI
Hes3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554866,272,757 - 6,273,721 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554866,272,757 - 6,273,721 (-)NCBIChiLan1.0ChiLan1.0
HES3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21221,977,474 - 221,981,958 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11220,618,837 - 220,623,273 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v015,008,155 - 5,012,868 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.116,264,032 - 6,268,002 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl16,265,738 - 6,266,937 (+)Ensemblpanpan1.1panPan2
HES3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1560,134,351 - 60,136,924 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl560,135,918 - 60,136,924 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha560,145,732 - 60,146,738 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0560,351,678 - 60,353,519 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl560,351,678 - 60,352,684 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1560,351,013 - 60,352,019 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0560,217,827 - 60,219,665 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0560,619,280 - 60,620,286 (+)NCBIUU_Cfam_GSD_1.0
Hes3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505830,607,847 - 30,613,685 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366231,096,870 - 1,097,858 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366231,096,519 - 1,098,175 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HES3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl667,133,482 - 67,135,292 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1667,134,259 - 67,138,639 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2662,038,600 - 62,042,601 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HES3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120125,493,703 - 125,500,577 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605429,600,131 - 29,601,550 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hes3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248185,153,717 - 5,161,026 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248185,156,428 - 5,160,858 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hes3
15 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:63
Count of miRNA genes:56
Interacting mature miRNAs:61
Transcripts:ENSRNOT00000014536
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5151113452164465185Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5151113452166875058Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5154828214166875058Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system nervous system renal system reproductive system respiratory system
High
Medium 12
Low 1 27 4
Below cutoff 10 9 7 2 7 13 1 12 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000014536   ⟹   ENSRNOP00000014535
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5162,794,367 - 162,796,261 (-)Ensembl
Rnor_6.0 Ensembl5169,464,989 - 169,467,153 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000118276   ⟹   ENSRNOP00000088398
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5162,794,367 - 162,795,698 (-)Ensembl
RefSeq Acc Id: NM_022687   ⟹   NP_073178
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85168,077,093 - 168,078,987 (-)NCBI
mRatBN7.25162,794,367 - 162,796,261 (-)NCBI
Rnor_6.05169,465,274 - 169,467,168 (-)NCBI
Rnor_5.05173,017,857 - 173,020,507 (-)NCBI
RGSC_v3.45169,516,965 - 169,518,859 (-)RGD
Celera5161,025,648 - 161,027,542 (-)RGD
Sequence:
RefSeq Acc Id: XM_008764381   ⟹   XP_008762603
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85168,076,337 - 168,082,270 (-)NCBI
mRatBN7.25162,793,611 - 162,799,578 (-)NCBI
Rnor_6.05169,463,196 - 169,469,774 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017593612   ⟹   XP_017449101
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85168,076,337 - 168,081,470 (-)NCBI
mRatBN7.25162,793,611 - 162,798,650 (-)NCBI
Rnor_6.05169,463,196 - 169,469,656 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017593614   ⟹   XP_017449103
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85168,076,337 - 168,081,470 (-)NCBI
mRatBN7.25162,793,611 - 162,798,650 (-)NCBI
Rnor_6.05169,463,196 - 169,469,656 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_073178   ⟸   NM_022687
- UniProtKB: Q04667 (UniProtKB/Swiss-Prot),   A6IUH9 (UniProtKB/TrEMBL),   A0A8I6AIT4 (UniProtKB/TrEMBL),   A6IUH8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008762603   ⟸   XM_008764381
- Peptide Label: isoform X1
- UniProtKB: Q04667 (UniProtKB/Swiss-Prot),   A6IUH9 (UniProtKB/TrEMBL),   A0A8I6AIT4 (UniProtKB/TrEMBL),   A6IUH8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449103   ⟸   XM_017593614
- Peptide Label: isoform X1
- UniProtKB: Q04667 (UniProtKB/Swiss-Prot),   A6IUH9 (UniProtKB/TrEMBL),   A0A8I6AIT4 (UniProtKB/TrEMBL),   A6IUH8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449101   ⟸   XM_017593612
- Peptide Label: isoform X1
- UniProtKB: Q04667 (UniProtKB/Swiss-Prot),   A6IUH9 (UniProtKB/TrEMBL),   A0A8I6AIT4 (UniProtKB/TrEMBL),   A6IUH8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000014535   ⟸   ENSRNOT00000014536
RefSeq Acc Id: ENSRNOP00000088398   ⟸   ENSRNOT00000118276
Protein Domains
bHLH   Orange

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q04667-F1-model_v2 AlphaFold Q04667 1-175 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621339 AgrOrtholog
BioCyc Gene G2FUF-39016 BioCyc
Ensembl Genes ENSRNOG00000010893 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055015907 UniProtKB/Swiss-Prot
  ENSRNOG00060003630 UniProtKB/Swiss-Prot
  ENSRNOG00065002068 UniProtKB/Swiss-Prot
  ENSRNOG00065009925 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000014536 ENTREZGENE
  ENSRNOT00000014536.4 UniProtKB/Swiss-Prot
  ENSRNOT00000118276.1 UniProtKB/TrEMBL
  ENSRNOT00055027065 UniProtKB/Swiss-Prot
  ENSRNOT00060005978 UniProtKB/Swiss-Prot
  ENSRNOT00065002716 UniProtKB/Swiss-Prot
  ENSRNOT00065015950 UniProtKB/Swiss-Prot
Gene3D-CATH 4.10.280.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Orange_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:64628 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 64628 ENTREZGENE
PANTHER BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR HES-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hes3 PhenoGen
PROSITE BHLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ORANGE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010893 RatGTEx
  ENSRNOG00055015907 RatGTEx
  ENSRNOG00060003630 RatGTEx
  ENSRNOG00065002068 RatGTEx
  ENSRNOG00065009925 RatGTEx
SMART HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6AIT4 ENTREZGENE, UniProtKB/TrEMBL
  A6IUH8 ENTREZGENE, UniProtKB/TrEMBL
  A6IUH9 ENTREZGENE, UniProtKB/TrEMBL
  HES3_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-11 Hes3  hes family bHLH transcription factor 3  Hes3  hairy and enhancer of split 3 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Hes3  hairy and enhancer of split 3 (Drosophila)    transcription factor HES-3  Name updated 1299863 APPROVED
2002-08-07 Hes3  transcription factor HES-3      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed only in cerebellar Purkinje cells 61625