Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Fgr | Rat | (R)-noradrenaline | increases expression | EXP | | 6480464 | Norepinephrine results in increased expression of FGR mRNA | CTD | PMID:14618266 | Fgr | Rat | 1,1-dichloroethene | increases expression | ISO | Fgr (Mus musculus) | 6480464 | vinylidene chloride results in increased expression of FGR mRNA | CTD | PMID:26682919 | Fgr | Rat | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of FGR mRNA | CTD | PMID:25380136 | Fgr | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Fgr (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FGR mRNA | CTD | PMID:17942748 | Fgr | Rat | 17beta-estradiol | multiple interactions | ISO | FGR (Homo sapiens) | 6480464 | [Estradiol binds to ESR2 protein] which results in increased expression of FGR mRNA | CTD | PMID:20404318 | Fgr | Rat | 17beta-estradiol | increases expression | ISO | FGR (Homo sapiens) | 6480464 | Estradiol results in increased expression of FGR mRNA | CTD | PMID:31614463 | Fgr | Rat | 17beta-estradiol | decreases expression | ISO | Fgr (Mus musculus) | 6480464 | Estradiol results in decreased expression of FGR mRNA | CTD | PMID:39298647 | Fgr | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Fgr (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FGR mRNA | CTD | PMID:17942748 | Fgr | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FGR mRNA | CTD | PMID:33387578 | Fgr | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of FGR mRNA | CTD | PMID:34747641 | Fgr | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Fgr (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of FGR mRNA | CTD | PMID:28922406 | Fgr | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | AHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of FGR mRNA] | CTD | PMID:21215274 | Fgr | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FGR mRNA | CTD | PMID:21215274 | Fgr | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | affects expression | ISO | Fgr (Mus musculus) | 6480464 | 2,2',4,4',5-brominated diphenyl ether affects the expression of FGR mRNA | CTD | PMID:38648751 | Fgr | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of FGR mRNA | CTD | PMID:21346803 | Fgr | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | FGR (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Fgr | Rat | 4,4'-diaminodiphenylmethane | increases expression | EXP | | 6480464 | 4,4'-diaminodiphenylmethane results in increased expression of FGR mRNA | CTD | PMID:25380136 | Fgr | Rat | 4-hydroxynon-2-enal | decreases expression | ISO | Fgr (Mus musculus) | 6480464 | 4-hydroxy-2-nonenal results in decreased expression of FGR mRNA | CTD | PMID:19191707 | Fgr | Rat | 4-hydroxynon-2-enal | increases expression | ISO | Fgr (Mus musculus) | 6480464 | 4-hydroxy-2-nonenal results in increased expression of FGR mRNA | CTD | PMID:19191707 | Fgr | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of FGR mRNA | CTD | PMID:24780913 | Fgr | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of FGR mRNA | CTD | PMID:31881176 | Fgr | Rat | acetylsalicylic acid | decreases expression | ISO | FGR (Homo sapiens) | 6480464 | Aspirin results in decreased expression of FGR mRNA | CTD | PMID:15928584 | Fgr | Rat | aflatoxin B1 | increases methylation | ISO | FGR (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of FGR intron | CTD | PMID:30157460 | Fgr | Rat | Aflatoxin B2 alpha | increases methylation | ISO | FGR (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of FGR intron | CTD | PMID:30157460 | Fgr | Rat | all-trans-retinoic acid | increases expression | ISO | FGR (Homo sapiens) | 6480464 | Tretinoin results in increased expression of FGR mRNA | CTD | PMID:15498508|PMID:16054129|PMID:28053092|PMID:33167477 | Fgr | Rat | all-trans-retinoic acid | multiple interactions | ISO | FGR (Homo sapiens) | 6480464 | [Arsenic Trioxide co-treated with Tretinoin] results in increased expression of FGR mRNA; KAT2B protein promotes more ... | CTD | PMID:28053092|PMID:38179723 | Fgr | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of FGR mRNA | CTD | PMID:16483693 | Fgr | Rat | antirheumatic drug | decreases expression | ISO | FGR (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of FGR mRNA | CTD | PMID:24449571 | Fgr | Rat | arsenous acid | increases expression | ISO | FGR (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of FGR mRNA | CTD | PMID:15761015 | Fgr | Rat | arsenous acid | multiple interactions | ISO | FGR (Homo sapiens) | 6480464 | [Arsenic Trioxide co-treated with Tretinoin] results in increased expression of FGR mRNA | CTD | PMID:38179723 | Fgr | Rat | benzalkonium chloride | increases expression | ISO | Fgr (Mus musculus) | 6480464 | Benzalkonium Compounds results in increased expression of FGR mRNA | CTD | PMID:30171875 | Fgr | Rat | benzo[a]pyrene | decreases expression | ISO | Fgr (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of FGR mRNA | CTD | PMID:21569818 | Fgr | Rat | benzo[a]pyrene | affects methylation | ISO | FGR (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of FGR 5' UTR; Benzo(a)pyrene affects the methylation of FGR promoter | CTD | PMID:27901495 | Fgr | Rat | bis(2-chloroethyl) sulfide | increases expression | ISO | Fgr (Mus musculus) | 6480464 | Mustard Gas results in increased expression of FGR mRNA | CTD | PMID:15674843 | Fgr | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of FGR mRNA | CTD | PMID:25181051 | Fgr | Rat | bisphenol A | decreases expression | ISO | Fgr (Mus musculus) | 6480464 | bisphenol A results in decreased expression of FGR mRNA | CTD | PMID:34585602 | Fgr | Rat | bisphenol A | increases expression | ISO | Fgr (Mus musculus) | 6480464 | bisphenol A results in increased expression of FGR mRNA | CTD | PMID:38701888 | Fgr | Rat | bisphenol A | multiple interactions | ISO | FGR (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Fgr | Rat | bosutinib | decreases activity | EXP | | 6480464 | bosutinib results in decreased activity of FGR protein | CTD | PMID:17114238 | Fgr | Rat | bromobenzene | decreases expression | EXP | | 6480464 | bromobenzene results in decreased expression of FGR mRNA | CTD | PMID:32479839 | Fgr | Rat | buta-1,3-diene | decreases expression | ISO | Fgr (Mus musculus) | 6480464 | 1,3-butadiene results in decreased expression of FGR mRNA | CTD | PMID:29038090 | Fgr | Rat | butan-1-ol | multiple interactions | ISO | FGR (Homo sapiens) | 6480464 | 1-Butanol inhibits the reaction [[N-Formylmethionine Leucyl-Phenylalanine co-treated with dihydrocytochalasin B] results in increased activity of more ... | CTD | PMID:11078731 | Fgr | Rat | Butylbenzyl phthalate | decreases expression | EXP | | 6480464 | butylbenzyl phthalate results in decreased expression of FGR mRNA | CTD | PMID:21241498 | Fgr | Rat | cadmium atom | multiple interactions | ISO | Fgr (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of FGR more ... | CTD | PMID:37236586 | Fgr | Rat | cadmium dichloride | increases expression | ISO | FGR (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of FGR mRNA | CTD | PMID:25596134 | Fgr | Rat | cadmium dichloride | multiple interactions | ISO | Fgr (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of FGR more ... | CTD | PMID:37236586 | Fgr | Rat | cadmium dichloride | decreases expression | ISO | FGR (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of FGR mRNA | CTD | PMID:38382870 | Fgr | Rat | carbon nanotube | increases expression | ISO | Fgr (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in increased expression of FGR mRNA; Nanotubes, Carbon results in increased more ... | CTD | PMID:25554681|PMID:25620056 | Fgr | Rat | chloroprene | decreases expression | EXP | | 6480464 | Chloroprene results in decreased expression of FGR mRNA | CTD | PMID:23125180 | Fgr | Rat | chloroprene | decreases expression | ISO | Fgr (Mus musculus) | 6480464 | Chloroprene results in decreased expression of FGR mRNA | CTD | PMID:23125180 | Fgr | Rat | chlorpromazine | decreases expression | EXP | | 6480464 | Chlorpromazine results in decreased expression of FGR mRNA | CTD | PMID:25596134 | Fgr | Rat | cisplatin | increases expression | ISO | FGR (Homo sapiens) | 6480464 | Cisplatin results in increased expression of FGR mRNA | CTD | PMID:27594783 | Fgr | Rat | Cuprizon | increases expression | EXP | | 6480464 | Cuprizone results in increased expression of FGR mRNA | CTD | PMID:27523638 | Fgr | Rat | cyclosporin A | decreases expression | EXP | | 6480464 | Cyclosporine results in decreased expression of FGR mRNA | CTD | PMID:25596134 | Fgr | Rat | dexamethasone | multiple interactions | ISO | FGR (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Fgr | Rat | diarsenic trioxide | increases expression | ISO | FGR (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of FGR mRNA | CTD | PMID:15761015 | Fgr | Rat | diarsenic trioxide | multiple interactions | ISO | FGR (Homo sapiens) | 6480464 | [Arsenic Trioxide co-treated with Tretinoin] results in increased expression of FGR mRNA | CTD | PMID:38179723 | Fgr | Rat | dichlorine | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] affects the expression of FGR mRNA | CTD | PMID:18636392 | Fgr | Rat | diethyl maleate | decreases expression | EXP | | 6480464 | diethyl maleate results in decreased expression of FGR mRNA | CTD | PMID:21161181 | Fgr | Rat | diethylstilbestrol | increases expression | ISO | FGR (Homo sapiens) | 6480464 | Diethylstilbestrol results in increased expression of FGR mRNA | CTD | PMID:15766595 | Fgr | Rat | Dihydrocytochalasin B | multiple interactions | ISO | FGR (Homo sapiens) | 6480464 | 1-Butanol inhibits the reaction [[N-Formylmethionine Leucyl-Phenylalanine co-treated with dihydrocytochalasin B] results in increased activity of more ... | CTD | PMID:11078731 | Fgr | Rat | dimethylarsinic acid | multiple interactions | ISO | Fgr (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Fgr | Rat | dioxygen | multiple interactions | EXP | | 6480464 | [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression more ... | CTD | PMID:33729688 | Fgr | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of FGR mRNA | CTD | PMID:29391264 | Fgr | Rat | fenofibrate | affects expression | EXP | | 6480464 | Fenofibrate affects the expression of FGR mRNA | CTD | PMID:25596134 | Fgr | Rat | fentanyl | increases expression | EXP | | 6480464 | Fentanyl results in increased expression of FGR mRNA | CTD | PMID:36032789 | Fgr | Rat | genistein | increases expression | ISO | Fgr (Mus musculus) | 6480464 | Genistein results in increased expression of FGR mRNA | CTD | PMID:32186404 | Fgr | Rat | hypochlorous acid | decreases expression | ISO | Fgr (Mus musculus) | 6480464 | Hypochlorous Acid results in decreased expression of FGR mRNA | CTD | PMID:19376150 | Fgr | Rat | indometacin | multiple interactions | ISO | FGR (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Fgr | Rat | leflunomide | decreases expression | EXP | | 6480464 | leflunomide results in decreased expression of FGR mRNA | CTD | PMID:24136188 | Fgr | Rat | lipopolysaccharide | increases expression | ISO | Fgr (Mus musculus) | 6480464 | Lipopolysaccharides results in increased expression of FGR mRNA | CTD | PMID:12057914 | Fgr | Rat | metformin | decreases expression | EXP | | 6480464 | Metformin results in decreased expression of FGR mRNA | CTD | PMID:25596134 | Fgr | Rat | methylarsonic acid | multiple interactions | ISO | Fgr (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Fgr | Rat | Moniliformin | increases expression | ISO | Fgr (Mus musculus) | 6480464 | moniliformin results in increased expression of FGR mRNA | CTD | PMID:39984025 | Fgr | Rat | Muraglitazar | increases expression | EXP | | 6480464 | muraglitazar results in increased expression of FGR mRNA | CTD | PMID:21515302 | Fgr | Rat | N-formyl-L-methionyl-L-leucyl-L-phenylalanine | multiple interactions | ISO | FGR (Homo sapiens) | 6480464 | 1-Butanol inhibits the reaction [[N-Formylmethionine Leucyl-Phenylalanine co-treated with dihydrocytochalasin B] results in increased activity of more ... | CTD | PMID:11078731 | Fgr | Rat | N-formyl-L-methionyl-L-leucyl-L-phenylalanine | increases phosphorylation | ISO | FGR (Homo sapiens) | 6480464 | N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of FGR protein | CTD | PMID:25980585 | Fgr | Rat | N-nitrosodimethylamine | increases expression | EXP | | 6480464 | Dimethylnitrosamine results in increased expression of FGR mRNA | CTD | PMID:25380136 | Fgr | Rat | nickel atom | decreases expression | ISO | FGR (Homo sapiens) | 6480464 | Nickel results in decreased expression of FGR mRNA | CTD | PMID:23195993 | Fgr | Rat | nickel atom | increases expression | ISO | FGR (Homo sapiens) | 6480464 | Nickel results in increased expression of FGR mRNA | CTD | PMID:25583101 | Fgr | Rat | nickel dichloride | affects expression | EXP | | 6480464 | nickel chloride affects the expression of FGR mRNA | CTD | PMID:22546817 | Fgr | Rat | ozone | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] affects the expression of FGR mRNA | CTD | PMID:18636392 | Fgr | Rat | paracetamol | increases expression | ISO | FGR (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of FGR mRNA | CTD | PMID:26690555 | Fgr | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of FGR mRNA | CTD | PMID:33387578 | Fgr | Rat | perfluorooctanoic acid | increases expression | EXP | | 6480464 | perfluorooctanoic acid results in increased expression of FGR mRNA | CTD | PMID:28511854 | Fgr | Rat | phosphatidic acid | increases activity | ISO | FGR (Homo sapiens) | 6480464 | Phosphatidic Acids results in increased activity of FGR protein | CTD | PMID:11078731 | Fgr | Rat | ponatinib | decreases activity | ISO | FGR (Homo sapiens) | 6480464 | ponatinib results in decreased activity of FGR protein | CTD | PMID:19878872 | Fgr | Rat | resveratrol | increases expression | EXP | | 6480464 | resveratrol results in increased expression of FGR mRNA | CTD | PMID:25905778 | Fgr | Rat | SB 431542 | increases expression | ISO | FGR (Homo sapiens) | 6480464 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of FGR protein | CTD | PMID:25670856 | Fgr | Rat | silicon dioxide | increases expression | ISO | FGR (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of FGR mRNA | CTD | PMID:23806026|PMID:25895662 | Fgr | Rat | sodium arsenate | multiple interactions | ISO | Fgr (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Fgr | Rat | sodium arsenate | decreases expression | ISO | Fgr (Mus musculus) | 6480464 | sodium arsenate results in decreased expression of FGR mRNA | CTD | PMID:39847705 | Fgr | Rat | sodium arsenite | decreases expression | ISO | FGR (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of FGR mRNA | CTD | PMID:29301061|PMID:38568856 | Fgr | Rat | sodium arsenite | multiple interactions | ISO | Fgr (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Fgr | Rat | sodium fluoride | increases expression | ISO | Fgr (Mus musculus) | 6480464 | Sodium Fluoride results in increased expression of FGR mRNA | CTD | PMID:27862939 | Fgr | Rat | tamibarotene | increases expression | ISO | FGR (Homo sapiens) | 6480464 | tamibarotene results in increased expression of FGR mRNA | CTD | PMID:15498508 | Fgr | Rat | Tesaglitazar | increases expression | EXP | | 6480464 | tesaglitazar results in increased expression of FGR mRNA | CTD | PMID:21515302 | Fgr | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of FGR mRNA | CTD | PMID:34492290 | Fgr | Rat | titanium dioxide | increases expression | ISO | Fgr (Mus musculus) | 6480464 | titanium dioxide results in increased expression of FGR mRNA | CTD | PMID:23557971 | Fgr | Rat | triphenyl phosphate | affects expression | ISO | FGR (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of FGR mRNA | CTD | PMID:37042841 | Fgr | Rat | triptonide | increases expression | ISO | Fgr (Mus musculus) | 6480464 | triptonide results in increased expression of FGR mRNA | CTD | PMID:33045310 | Fgr | Rat | troglitazone | increases expression | ISO | Fgr (Mus musculus) | 6480464 | troglitazone results in increased expression of FGR mRNA | CTD | PMID:28973697 | Fgr | Rat | tungsten | decreases expression | ISO | Fgr (Mus musculus) | 6480464 | Tungsten results in decreased expression of FGR mRNA | CTD | PMID:30912803 | Fgr | Rat | valproic acid | increases methylation | ISO | FGR (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of FGR gene | CTD | PMID:29154799 | Fgr | Rat | vincristine | decreases expression | ISO | FGR (Homo sapiens) | 6480464 | Vincristine results in decreased expression of FGR mRNA | CTD | PMID:23649840 | |






















