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Gene: Arf2 (ADP-ribosylation factor 2) Rattus norvegicus

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Symbol:

Arf2 (Ensembl: Arf1)

Name:

ADP-ribosylation factor 2 (Ensembl:ADP-ribosylation factor 1)

RGD ID:

621271

Description:

Predicted to enable GTP binding activity. Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Predicted to be located in Golgi apparatus. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human ARL17B (ARF like GTPase 17B); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; alpha-Zearalanol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

MGC114313

RGD Orthologs

Human

Mouse

Pig

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ARL17B (ARF like GTPase 17B)	HGNC	EggNOG, Ensembl
Mus musculus (house mouse):	Arf2 (ARF GTPase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ARF2 (ADP-ribosylation factor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ARF1 (ARF GTPase 1)	HGNC	OrthoDB, Treefam
Homo sapiens (human):	ARF3 (ARF GTPase 3)	HGNC	OrthoDB
Homo sapiens (human):	ARL17A (ARF like GTPase 17A)	HGNC	Ensembl
Alliance orthologs ³
Mus musculus (house mouse):	Arf2 (ARF GTPase 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ARL17A (ARF like GTPase 17A)	Alliance	DIOPT (HGNC)
Homo sapiens (human):	ARL17B (ARF like GTPase 17B)	Alliance	DIOPT (HGNC\|PhylomeDB)
Danio rerio (zebrafish):	arf2b (ADP-ribosylation factor 2b)	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PhylomeDB)
Danio rerio (zebrafish):	arf1 (ADP-ribosylation factor 1)	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	arf2a (ADP-ribosylation factor 2a)	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	ARF1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	ARF1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	ARF2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	ARF2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Arf79F	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|PANTHER)
Drosophila melanogaster (fruit fly):	Arf79F	Alliance	DIOPT (Hieranoid\|OMA\|OrthoFinder\|PANTHER)
Caenorhabditis elegans (roundworm):	arf-1.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	arf-1.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	arf1	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	89,367,843 - 89,389,644 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	89,368,044 - 89,389,651 (+)	Ensembl				GRCr8
mRatBN7.2	10	88,867,836 - 88,889,654 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	88,867,836 - 88,889,659 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	93,906,655 - 93,928,391 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	93,370,144 - 93,391,815 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	88,765,181 - 88,786,917 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	10	92,512,470 - 92,534,125 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	10	93,243,364 - 93,265,019 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	10	94,688,959 - 94,710,614 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	10	94,792,786 - 94,814,463 (+)	NCBI		F344_StmMcwi
Rnor_6.0	10	92,018,562 - 92,040,335 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	92,018,562 - 92,040,333 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	91,783,781 - 91,805,591 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	93,114,540 - 93,136,313 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	87,565,485 - 87,587,254 (+)	NCBI		Celera
RGSC_v3.1	10	93,128,909 - 93,150,681 (+)	NCBI
Cytogenetic Map	10	q32.1	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

hereditary breast ovarian cancer syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP,ISO)

17beta-estradiol (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-vinylcyclohexene dioxide (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

alpha-Zearalanol (EXP)

amitrole (EXP)

amphetamine (EXP)

arsane (ISO)

arsenic atom (ISO)

azoxystrobin (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

Butylbenzyl phthalate (ISO)

chlorpyrifos (EXP)

copper(II) sulfate (ISO)

dexamethasone (ISO)

fenvalerate (EXP)

furan (EXP)

gentamycin (EXP)

glyphosate (EXP)

imidacloprid (EXP)

indometacin (ISO)

isoprenaline (ISO)

leflunomide (ISO)

oxazepam (ISO)

paracetamol (ISO)

perfluorohexanesulfonic acid (ISO)

perfluorooctanoic acid (EXP)

phenobarbital (ISO)

pirinixic acid (ISO)

S-nitrosoglutathione (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

succimer (ISO)

tamoxifen (ISO)

tetrachloromethane (EXP)

thiabendazole (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

triptonide (ISO)

trovafloxacin (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

intracellular protein transport (IBA)

protein transport (IEA)

vesicle-mediated transport (IBA,IEA)

Cellular Component

cytoplasm (IBA)

Golgi apparatus (IEA,ISO,ISS)

nucleoplasm (ISO)

plasma membrane (IBA)

Molecular Function

GTP binding (IBA,IEA)

GTPase activity (IEA)

metal ion binding (IEA)

nucleotide binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
4.	Interspecies relationships among ADP-ribosylation factors (ARFs): evidence of evolutionary pressure to maintain individual identities.	Price SR, etal., Mol Cell Biochem 1996 Jun 7;159(1):15-23.
5.	GOA pipeline	RGD automated data pipeline
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8947846	PMID:12477932	PMID:22082260	PMID:24625528	PMID:32357304

Genomics

Comparative Map Data

Arf2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	89,367,843 - 89,389,644 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	89,368,044 - 89,389,651 (+)	Ensembl				GRCr8
mRatBN7.2	10	88,867,836 - 88,889,654 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	88,867,836 - 88,889,659 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	93,906,655 - 93,928,391 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	93,370,144 - 93,391,815 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	88,765,181 - 88,786,917 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	10	92,512,470 - 92,534,125 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	10	93,243,364 - 93,265,019 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	10	94,688,959 - 94,710,614 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	10	94,792,786 - 94,814,463 (+)	NCBI		F344_StmMcwi
Rnor_6.0	10	92,018,562 - 92,040,335 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	92,018,562 - 92,040,333 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	91,783,781 - 91,805,591 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	93,114,540 - 93,136,313 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	87,565,485 - 87,587,254 (+)	NCBI		Celera
RGSC_v3.1	10	93,128,909 - 93,150,681 (+)	NCBI
Cytogenetic Map	10	q32.1	NCBI

ARL17B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	46,274,184 - 46,361,787 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	46,274,184 - 46,361,766 (-)	Ensembl			hg38	GRCh38
GRCh38.p14 Ensembl	17	46,499,780 - 46,579,695 (-)	Ensembl			hg38	GRCh38
GRCh37	17	44,351,550 - 44,439,153 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	41,784,502 - 41,794,826 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Cytogenetic Map	17	q21.31	NCBI
HuRef	17	40,477,082 - 40,477,202 (-)	NCBI		HuRef
HuRef	17	39,312,323 - 39,312,702 (+)	NCBI		HuRef
CHM1_1	17	43,815,492 - 43,870,139 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	47,136,194 - 47,223,769 (-)	NCBI		T2T-CHM13v2.0

Arf2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	103,857,551 - 103,876,176 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	103,857,565 - 103,876,163 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	11	103,966,725 - 103,985,350 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	103,966,739 - 103,985,337 (+)	Ensembl			mm10	GRCm38
MGSCv37	11	103,828,185 - 103,846,650 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	11	103,782,961 - 103,801,426 (+)	NCBI		MGSCv36	mm8
Celera	11	115,682,724 - 115,701,306 (+)	NCBI		Celera
Cytogenetic Map	11	E1	NCBI
cM Map	11	67.64	NCBI

ARF2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	12	17,432,594 - 17,447,976 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	17,474,691 - 17,479,635 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Pig Cytomap	12	p13	NCBI

Variants

Variants in Arf2
202 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	193
Count of miRNA genes:	134
Interacting mature miRNAs:	167
Transcripts:	ENSRNOT00000006483
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1549846	Scl47	Serum cholesterol level QTL 47	3.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	10	51071897	96071897	Rat
1298069	Bp168	Blood pressure QTL 168	5.5		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	10	27023535	98502431	Rat
8657410	Bp374	Blood pressure QTL 374			heart left ventricle size trait (VT:0002753)	heart left ventricle end-diastolic diameter (CMO:0000982)	10	67476608	107713808	Rat
631552	Vetf2	Vascular elastic tissue fragility QTL 2	4.5	0.0002	aorta elastic tissue integrity trait (VT:0010556)	artery internal elastic lamina non-tumorous lesion count (CMO:0001913)	10	35509383	91417879	Rat
61449	Ciaa2	CIA Autoantibody QTL 2	7.1		blood autoantibody amount (VT:0003725)	calculated serum anti-type 2 collagen antibody titer (CMO:0001279)	10	63719161	107713808	Rat
631555	Bp134	Blood pressure QTL 134		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	81012077	91729860	Rat
61325	Aia5	Adjuvant induced arthritis QTL 5		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
1298078	Stresp5	Stress response QTL 5	2.99	0.00025	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	10	42546145	107713808	Rat
1549831	Bss6	Bone structure and strength QTL 6	4		lumbar vertebra strength trait (VT:0010574)	vertebra ultimate force (CMO:0001678)	10	58073360	103073360	Rat
12903252	Cm113	Cardiac mass QTL 113		0.047	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	10	66817119	107713808	Rat
70164	Bw21	Body weight QTL 21	4.36	0.00005	body mass (VT:0001259)	body weight (CMO:0000012)	10	54296336	99451733	Rat
4889948	Bss91	Bone structure and strength QTL 91	4		tibia area (VT:1000281)	tibia midshaft total cross-sectional area (CMO:0001715)	10	83061236	92869129	Rat
1579919	Bp281	Blood pressure QTL 281		0.01	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	50464802	95464802	Rat
2298548	Neuinf7	Neuroinflammation QTL 7	3.4		nervous system integrity trait (VT:0010566)	spinal cord RT1-B protein level (CMO:0002132)	10	64939013	107713808	Rat
1302404	Cia27	Collagen induced arthritis QTL 27	2.6	0.0045	joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	10	76951790	107713808	Rat
1300107	Rf18	Renal function QTL 18	3.41		urine output (VT:0003620)	timed urine volume (CMO:0000260)	10	79272424	102982300	Rat
8694173	Bw149	Body weight QTL 149	4.38	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	10	44939359	89939359	Rat
2300218	Hpcl2	Hepatic cholesterol level QTL 2			liver cholesterol amount (VT:0010498)	liver cholesterol level (CMO:0001597)	10	45529164	96099749	Rat
70168	Eae12	Experimental allergic encephalomyelitis QTL 12		0.0009	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	10	73599825	107713808	Rat
70171	Cari1	Carrageenan-induced inflammation QTL 1	4.9	0.0005	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	10	54296227	107713808	Rat
10450495	Bp383	Blood pressure QTL 383		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	76743133	95464802	Rat
12903269	Am15	Aortic mass QTL 15		0.042	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	10	66817119	107713808	Rat
10450493	Bp382	Blood pressure QTL 382		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	50860288	95860288	Rat
2313856	Bp342	Blood pressure QTL 342	4.4	0.0001	life span trait (VT:0005372)	age at time of death (CMO:0001193)	10	87807758	96620484	Rat
12903266	Cm114	Cardiac mass QTL 114		0.02	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	10	66817119	107713808	Rat
61354	Pia10	Pristane induced arthritis QTL 10		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
2292617	Ept18	Estrogen-induced pituitary tumorigenesis QTL 18	3.9		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	10	73950353	96620293	Rat
2313103	Bss80	Bone structure and strength QTL 80	2	0.0001	tibia strength trait (VT:1000284)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	10	62556066	107556066	Rat
12880372	Am12	Aortic mass QTL 12		0.003	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	10	66817119	107713808	Rat
70193	Mcs7	Mammary carcinoma susceptibility QTL 7	2.38		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	10	72724423	107713808	Rat
2313105	Bss79	Bone structure and strength QTL 79	1.8	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	10	62556066	107556066	Rat
12880375	Kidm66	Kidney mass QTL 66		0.009	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	10	66817119	107713808	Rat
61363	Oia3	Oil induced arthritis QTL 3		0.001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	87807758	107713808	Rat
9589030	Epfw9	Epididymal fat weight QTL 9	19.24	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	10	44939359	89939359	Rat
1357344	Bp249	Blood pressure QTL 249		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	67241334	98502431	Rat
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14991535	107556066	Rat
12880370	Cm105	Cardiac mass QTL 105		0.008	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	10	66817119	107713808	Rat
12880371	Cm106	Cardiac mass QTL 106		0.007	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	10	66817119	107713808	Rat
2306970	Anxrr22	Anxiety related response QTL 22	5.95		fear/anxiety-related behavior trait (VT:1000241)	number of periods of voluntary immobility (CMO:0001045)	10	61843496	98710773	Rat
11565453	Kidm58	Kidney mass QTL 58		0.002	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	10	66817119	107713808	Rat
1359017	Hrtrt21	Heart rate QTL 21	2.4		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	10	73695339	97272278	Rat
7387312	Bw125	Body weight QTL 125	3	0.0047	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight (CMO:0000356)	10	65390777	107713808	Rat
6893357	Bw102	Body weight QTL 102	0.5	0.36	body mass (VT:0001259)	body weight (CMO:0000012)	10	81012077	101828297	Rat
724556	Pur2	Proteinuria QTL 2	5.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	22931373	91127454	Rat
2306793	Ean5	Experimental allergic neuritis QTL 5	4.7		nervous system integrity trait (VT:0010566)	IFNG-secreting splenocyte count (CMO:0002122)	10	73049656	94495280	Rat
2306792	Ean4	Experimental allergic neuritis QTL 4	4		nervous system integrity trait (VT:0010566)	IFNG-secreting splenocyte count (CMO:0002122)	10	49495492	94495492	Rat
61387	Bp1	Blood pressure QTL 1	5.1		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	52269185	107713808	Rat
61396	Bp9	Blood pressure QTL 9	4.8	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	68920187	107713808	Rat
1358915	Stresp7	Stress response QTL 7	3.52		blood norepinephrine amount (VT:0005663)	plasma norepinephrine level (CMO:0001010)	10	65307813	107713808	Rat
634320	Niddm49	Non-insulin dependent diabetes mellitus QTL 49	4.41		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	10	89039175	107713808	Rat
70363	Bp71	Blood pressure QTL 71		0.04	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	61843496	106843496	Rat
1331791	Cm31	Cardiac mass QTL 31	3.84606		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	29800910	91417879	Rat
70364	Bp72	Blood pressure QTL 72			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	88900501	96620484	Rat
6893366	Bw106	Body weight QTL 106	0.3	0.47	body mass (VT:0001259)	body weight (CMO:0000012)	10	70698731	107713808	Rat
631530	Tls3	T-lymphoma susceptibility QTL 3	0	0.0001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	10	27587226	96099902	Rat
1354608	Cm33	Cardiac mass QTL 33	2.8		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	10	55307972	93608131	Rat
1558643	Cm44	Cardiac mass QTL 44	4.8	0.0000368	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	61843496	100198886	Rat
631267	Cia20	Collagen induced arthritis QTL 20	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
631269	Cia22	Collagen induced arthritis QTL 22	8.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	40535708	107713808	Rat
1576308	Schws1	Schwannoma susceptibility QTL 1		0.0041	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	10	40535708	107713808	Rat
631268	Cia21	Collagen induced arthritis QTL 21	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	14991535	107713808	Rat
7207811	Bmd90	Bone mineral density QTL 90	5.2		femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	10	49943710	94943710	Rat
631270	Cia23	Collagen induced arthritis QTL 23	3.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	40535708	107713808	Rat
7411614	Foco18	Food consumption QTL 18		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	10	44939359	89939359	Rat
1581559	Eae18	Experimental allergic encephalomyelitis QTL 18		0.00002	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	10	66108888	107555881	Rat
6893336	Cm75	Cardiac mass QTL 75	0.1	0.87	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	10	61843496	100198886	Rat
631547	Bp87	Blood pressure QTL 87	4.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	47869129	92869129	Rat
61427	Cia16	Collagen induced arthritis QTL 16	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	6864618	96620484	Rat
12880055	Am11	Aortic mass QTL 11		0.004	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	10	84503487	96432422	Rat
2292438	Bp311	Blood pressure QTL 311			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	76743133	95604677	Rat
2301398	Kidm38	Kidney mass QTL 38		0.002	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	10	84503487	96432422	Rat
2292436	Bp310	Blood pressure QTL 310			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	50604677	95604677	Rat
1600367	Mcs15	Mammary carcinoma susceptibility QTL 15	4.5		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	10	72724423	107713808	Rat
1358188	Ept9	Estrogen-induced pituitary tumorigenesis QTL 9	3.9		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	10	73950353	96620293	Rat
631537	Oia4	Oil induced arthritis QTL 4			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	76128947	107713808	Rat
634354	Rends3	Renal damage susceptibility QTL 3		0.05	kidney blood vessel morphology trait (VT:0000530)	organ lesion measurement (CMO:0000677)	10	61997479	106997479	Rat
2301405	Cm69	Cardiac mass QTL 69		0.031	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	10	66817119	107713808	Rat
631542	Bp82	Blood pressure QTL 82	6.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	27023535	99451848	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	162	91	90	59	92	59	6	356	192	11	141	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_024150	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039086909	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC131613	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC098915	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	L12381	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000006483 ⟹ ENSRNOP00000006483

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	89,368,044 - 89,389,626 (+)	Ensembl
mRatBN7.2 Ensembl	10	88,867,836 - 88,889,659 (+)	Ensembl
Rnor_6.0 Ensembl	10	92,018,562 - 92,040,333 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000113470 ⟹ ENSRNOP00000077987

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	89,368,395 - 89,389,651 (+)	Ensembl
mRatBN7.2 Ensembl	10	88,868,290 - 88,889,597 (+)	Ensembl

RefSeq Acc Id:

NM_024150 ⟹ NP_077064

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	89,367,843 - 89,389,624 (+)	NCBI
mRatBN7.2	10	88,867,836 - 88,889,619 (+)	NCBI
Dahl_SR_JrHsd	10	92,512,470 - 92,534,125 (+)	NCBI
Lyon_Normotensive	10	93,243,364 - 93,265,019 (+)	NCBI
Lyon_Hypertensive	10	94,688,959 - 94,710,614 (+)	NCBI
F344_StmMcwi	10	94,792,786 - 94,814,463 (+)	NCBI
Rnor_6.0	10	92,018,562 - 92,040,335 (+)	NCBI
Rnor_5.0	10	91,783,781 - 91,805,591 (+)	NCBI
RGSC_v3.4	10	93,114,540 - 93,136,313 (+)	RGD
Celera	10	87,565,485 - 87,587,254 (+)	RGD

Sequence:

show sequence

GGTGGAGTAGCGGTTTCCTTAGTGGCTTTGTGAAGGTGTTCACTGCAGAGACTGGTTGCAGAAT
TCAGCTACGATGGGGAACGTTTTTGAAAAGCTGTTTAAAAGCCTATTTGGGAAAAAGGAAATGC
GGATTCTCATGGTGGGCTTAGATGCAGCTGGCAAAACGACGATCTTGTACAAACTGAAGCTGGG
AGAGATTGTGACAACCATCCCCACCATAGGTTTCAACGTGGAGACCGTAGAATATAAAAACATC
AGCTTCACAGTCTGGGATGTTGGTGGCCAGGACAAAATCAGACCTTTGTGGCGACATTACTTCC
AGAACACTCAAGGTCTGATATTCGTGGTTGATAGTAACGACAGAGAGCGGGTCAATGAGGCCCG
GGAAGAACTGACCAGAATGCTAGCAGAAGATGAGCTCAGAGACGCAGTCTTATTGGTGTTTGTA
AACAAACAGGATCTTCCTAATGCTATGAACGCAGCAGAGATCACAGACAAGCTTGGCTTACATT
CACTTCGCCAGAGAAACTGGTACATTCAGGCTACCTGTGCGACCAGTGGAGATGGGCTTTACGA
AGGCCTGGACTGGCTCTCCAACCAACTCAAGAACCAGAAGTGATCAGAAGCAGCCCATTCCCCA
TGCCTTGTGGCAAAGGCAGCTGGCCTTTCCCGTGTGCATGTGAGTGCGTGAGGAGCCATGTGGC
CGTGTGGCTGGGAGTGGGGCAGCTTTCTCACACCGTGCCTTATCCACGCTATACGAACACCAGT
ACTCCATTTTAAGAAAACCAGTGTTACATTTGGAATGCTACCGTCCATTTCACGAGCTTTGATG
GTCTTTTCGCTGAGGCCTCCCCGGTGTGATAGCCAGAATATCTCTAGGCTGGAAAAGAAGAGAG
CTGGAGGCAGGCAGGTCCCGTTGTTGCCATCCTGGGTTTGGCCTCTCCACACACTCGGAATCCC
GTTGGACTTTGGTGTCCTTTTACAAAAAGAAAGGAAGGGCTGCCATTCTTTCCATTGTGCCAAA
GCTAGCAGCTCACTTGTAGTGCTTTAAAGCTGTCAAGAAGAAGGATACGTTATTACCACAGTGT
GAGAGGTTCAGAGGGGAATACTTCCCCAGAGTTCTGTTAGTTCAAACTGACGCATTTAGCTGTT
TTAGTCCAAGGAATCAGTGACCTTTTTCATTAGAGTATCAAGACTGTAACACTAGAGAAGTTTC
CAGCCTGTCCCATACTTGCCAAACGGAAACTCTGTGGGCTGCTGGCCCAACAGGAGGCCAGAAC
TCTTCCCCTAAGCCTCCTGGTCCACAGCGGAGTAAAGGTTGTGGGGAGTGAAGTGAGGTAGCTC
TTGTGTTCTGGCATCACGTCTCAGTCCCCTGAGGCTGCTGCTCCCACTTCTCTGCTCTGTGCTG
AGTGTTCTTCACATGCAGCAGACAGTGCTCCTGGTGGAGTTGTCACTGTGTCCCCTTGTCCTGG
TCTACTGTGGGCTTTTGATTAGTATCTGTTTCCAGAACCGCACACCCGTGAGTTCTGAGTGTGT
GTGAGAAAGTCAGGAGGTTAATTTAGAAGATGAAGGTCCCAGTGGCCCCCATACTCCCTGGGTT
GGTGCTAAACTTTGCTCTGAGAAGCGCCTTTTCTTCAGACTGCTCTCACTCTCCCTCATCAATG
GCAGTGGCATCTGAAGAGCAGCTTGGATATGTGTGCTGTGTCGTCCTGCAGATAGTTGATAGGA
AGGCCCAGAGAGGAGCTGGCTTCAGCCCTAAGCCCTTCTGGCCACATAGCTCTGGGCCACATTT
GTACCTAAGCCCCTTTACTGCTTAATGTTTTAAAACTCCTTTCAGAAAAAAATTAACCCCTGCT
ACAGAAGGGGGAATGCAAACTGAACTTCAAATAAATCTTGTTCATTGGTAACAAAGTTAAGCTA
GGAAAAAAAATTCCATGCCATTGTAAATGTGAGCTGTGATGTTTTTCTTTAAAATATCTTGAAT
GTTCATTGCAATACTGGTGACTGAGTCCAGATGTGATTTTTAACGTCAGATGAATTCCTGAGAA
ATGTTTAAGTTGTACACCTCCCATTGGCTGGGAGCCTCTTGCCCTTTGTAATTATGCTTAGTGT
GCCTGGCCTGGTGCTAGGCTGCAGTAAACCTGGTGACTGGTTAGATAATAAAGAACTTACTTGG
GAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039086909 ⟹ XP_038942837

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	89,368,093 - 89,389,644 (+)	NCBI
mRatBN7.2	10	88,867,954 - 88,889,654 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_077064	(Get FASTA)	NCBI Sequence Viewer
	XP_038942837	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA40686	(Get FASTA)	NCBI Sequence Viewer
	AAH98915	(Get FASTA)	NCBI Sequence Viewer
	EDM06289	(Get FASTA)	NCBI Sequence Viewer
	EDM06290	(Get FASTA)	NCBI Sequence Viewer
	EDM06291	(Get FASTA)	NCBI Sequence Viewer
	EDM06292	(Get FASTA)	NCBI Sequence Viewer
	EDM06293	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000006483
	ENSRNOP00000006483.4
	ENSRNOP00000077987
GenBank Protein	P84082	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_077064 ⟸ NM_024150
- UniProtKB:	Q4KM00 (UniProtKB/Swiss-Prot), P84082 (UniProtKB/Swiss-Prot), A6HJT6 (UniProtKB/TrEMBL), A0A8I5ZKF2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGNVFEKLFKSLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFT VWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELTRMLAEDELRDAVLLVFVNKQ DLPNAMNAAEITDKLGLHSLRQRNWYIQATCATSGDGLYEGLDWLSNQLKNQK hide sequence

Ensembl Acc Id:

ENSRNOP00000006483 ⟸ ENSRNOT00000006483

RefSeq Acc Id:	XP_038942837 ⟸ XM_039086909
- Peptide Label:	isoform X1
- UniProtKB:	P84082 (UniProtKB/Swiss-Prot), Q4KM00 (UniProtKB/Swiss-Prot), A6HJT6 (UniProtKB/TrEMBL), A0A8I5ZKF2 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000077987 ⟸ ENSRNOT00000113470

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P84082-F1-model_v2	AlphaFold	P84082	1-181	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13697817

Promoter ID:

EPDNEW_R8342

Type:

initiation region

Name:

Arf2_1

Description:

ADP-ribosylation factor 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	10	92,018,542 - 92,018,602	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621271	AgrOrtholog
BioCyc Gene	G2FUF-23024	BioCyc
Ensembl Genes	ENSRNOG00000004807	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000006483	ENTREZGENE
	ENSRNOT00000006483.6	UniProtKB/Swiss-Prot
	ENSRNOT00000113470	ENTREZGENE
Gene3D-CATH	3.40.50.300	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7461110	IMAGE-MGC_LOAD
InterPro	Arf1_5_like	UniProtKB/Swiss-Prot
	P-loop_NTPase	UniProtKB/Swiss-Prot
	Small_GTP-bd_dom	UniProtKB/Swiss-Prot
	Small_GTPase_ARF	UniProtKB/Swiss-Prot
	Small_GTPase_ARF/SAR	UniProtKB/Swiss-Prot
KEGG Report	rno:79119	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:114313	IMAGE-MGC_LOAD
NCBI Gene	79119	ENTREZGENE
PANTHER	PTHR11711	UniProtKB/Swiss-Prot
Pfam	Arf	UniProtKB/Swiss-Prot
PhenoGen	Arf2	PhenoGen
PRINTS	SAR1GTPBP	UniProtKB/Swiss-Prot
PROSITE	ARF	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000004807	RatGTEx
SMART	ARF	UniProtKB/Swiss-Prot
	RAB	UniProtKB/Swiss-Prot
	SAR	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF52540	UniProtKB/Swiss-Prot
UniProt	A0A8I5ZKF2	ENTREZGENE, UniProtKB/TrEMBL
	A6HJT4_RAT	UniProtKB/TrEMBL
	A6HJT6	ENTREZGENE, UniProtKB/TrEMBL
	A6HJT8_RAT	UniProtKB/TrEMBL
	ARF2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q4KM00	ENTREZGENE
UniProt Secondary	P10947	UniProtKB/Swiss-Prot
	P16500	UniProtKB/Swiss-Prot
	Q4KM00	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-09-10	Arf2	ADP-ribosylation factor 2			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Arf2	ADP-ribosylation factor 2			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar