Inhbe (inhibin subunit beta E) - Rat Genome Database

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Gene: Inhbe (inhibin subunit beta E) Rattus norvegicus
Analyze
Symbol: Inhbe
Name: inhibin subunit beta E
RGD ID: 621196
Description: Predicted to enable cytokine activity. Predicted to be involved in cell surface receptor protein serine/threonine kinase signaling pathway and negative regulation of adipose tissue development. Predicted to act upstream of or within activin receptor signaling pathway. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human INHBE (inhibin subunit beta E); PARTICIPATES IN transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: activin beta E; activin beta-E chain; inhibin beta E; inhibin beta E chain; inhibin beta E subunit
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8765,061,531 - 65,064,519 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl765,061,531 - 65,064,519 (-)EnsemblGRCr8
mRatBN7.2763,176,221 - 63,179,209 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl763,176,219 - 63,179,172 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx765,066,840 - 65,068,267 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0767,269,266 - 67,270,691 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0767,070,582 - 67,072,002 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0770,641,423 - 70,642,848 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl770,640,075 - 70,643,169 (-)Ensemblrn6Rnor6.0
Rnor_5.0770,815,702 - 70,817,127 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4767,308,713 - 67,310,138 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera760,317,558 - 60,318,983 (-)NCBICelera
RGSC_v3.1767,328,105 - 67,331,057 (-)NCBI
Cytogenetic Map7q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,4-dithiothreitol  (ISO)
1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine  (ISO)
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3',5'-cyclic AMP  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-diaminodiphenylmethane  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
amiodarone  (EXP,ISO)
amitriptyline  (ISO)
ammonium chloride  (EXP)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
azoxystrobin  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bosentan  (ISO)
cadmium dichloride  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
carnosic acid  (ISO)
chlorotoluron  (ISO)
chlorpromazine  (ISO)
choline  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (EXP,ISO)
citalopram  (ISO)
clarithromycin  (ISO)
clofibrate  (EXP)
clomipramine  (ISO)
clozapine  (ISO)
cobalt dichloride  (EXP,ISO)
corn oil  (EXP)
cyclosporin A  (ISO)
cyproconazole  (ISO)
decabromodiphenyl ether  (EXP)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
dimethylarsinic acid  (EXP)
disodium selenite  (ISO)
dorsomorphin  (ISO)
doxepin  (ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
erythromycin A  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fentin chloride  (EXP)
flecainide  (ISO)
fluoxetine  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (ISO)
genistein  (ISO)
gentamycin  (EXP)
haloperidol  (ISO)
hydrazine  (ISO)
hydroquinone  (ISO)
imipramine  (ISO)
inulin  (ISO)
iron dichloride  (ISO)
isoniazide  (ISO)
ketoconazole  (ISO)
L-1,4-dithiothreitol  (ISO)
L-ascorbic acid  (ISO)
L-ethionine  (EXP)
lead diacetate  (ISO)
leflunomide  (EXP,ISO)
Licochalcone B  (ISO)
lipopolysaccharide  (EXP,ISO)
loratadine  (ISO)
mercury dibromide  (ISO)
metacetamol  (ISO)
methapyrilene  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
N-Nitrosopyrrolidine  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (EXP)
nelfinavir  (ISO)
nevirapine  (EXP,ISO)
niclosamide  (ISO)
nimesulide  (EXP)
nitrofen  (EXP)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
omeprazole  (EXP)
oxycodone  (EXP)
p-chloromercuribenzoic acid  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
PCB138  (ISO)
pentamidine  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (ISO)
perhexiline  (ISO)
phenformin  (EXP)
phenobarbital  (EXP,ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
quinidine  (ISO)
quinolin-8-ol  (ISO)
ranitidine  (EXP)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sertraline  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sotalol  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tebuconazole  (ISO)
temozolomide  (ISO)
Tesaglitazar  (EXP)
tetrachloromethane  (ISO)
tetracycline  (ISO)
thapsigargin  (ISO)
thifluzamide  (ISO)
thioacetamide  (EXP)
thioridazine  (ISO)
trichloroethene  (EXP)
triptonide  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vincristine  (ISO)
zimeldine  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Overexpression of activin beta(C) or activin beta(E) in the mouse liver inhibits regenerative deoxyribonucleic acid synthesis of hepatic cells. Chabicovsky M, etal., Endocrinology 2003 Aug;144(8):3497-504.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. Cloning and regulation of the rat activin betaE subunit. O'Bryan MK, etal., J Mol Endocrinol 2000 Jun;24(3):409-18.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Expression and dimerization of the rat activin subunits betaC and betaE: evidence for the ormation of novel activin dimers. Vejda S, etal., J Mol Endocrinol 2002 Apr;28(2):137-48.
Additional References at PubMed
PMID:16935389  


Genomics

Comparative Map Data
Inhbe
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8765,061,531 - 65,064,519 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl765,061,531 - 65,064,519 (-)EnsemblGRCr8
mRatBN7.2763,176,221 - 63,179,209 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl763,176,219 - 63,179,172 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx765,066,840 - 65,068,267 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0767,269,266 - 67,270,691 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0767,070,582 - 67,072,002 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0770,641,423 - 70,642,848 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl770,640,075 - 70,643,169 (-)Ensemblrn6Rnor6.0
Rnor_5.0770,815,702 - 70,817,127 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4767,308,713 - 67,310,138 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera760,317,558 - 60,318,983 (-)NCBICelera
RGSC_v3.1767,328,105 - 67,331,057 (-)NCBI
Cytogenetic Map7q22NCBI
INHBE
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381257,455,307 - 57,458,025 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1257,452,323 - 57,459,280 (+)Ensemblhg38GRCh38
GRCh371257,849,090 - 57,851,808 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361256,135,363 - 56,138,058 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341256,135,362 - 56,138,056NCBI
Celera1257,503,083 - 57,505,778 (+)NCBICelera
Cytogenetic Map12q13.3NCBI
HuRef1254,886,854 - 54,889,664 (+)NCBIHuRef
CHM1_11257,817,205 - 57,819,905 (+)NCBICHM1_1
T2T-CHM13v2.01257,423,596 - 57,426,314 (+)NCBIT2T-CHM13v2.0
Inhbe
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910127,185,271 - 127,187,717 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10127,184,726 - 127,190,280 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3810127,349,402 - 127,351,848 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10127,348,857 - 127,354,411 (-)Ensemblmm10GRCm38
MGSCv3710126,786,458 - 126,788,828 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3610126,752,351 - 126,754,721 (-)NCBIMGSCv36mm8
Celera10129,741,900 - 129,744,264 (-)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1074.5NCBI
Inhbe
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554585,177,036 - 5,179,095 (+)Ensembl
ChiLan1.0NW_0049554585,177,036 - 5,179,095 (+)NCBIChiLan1.0ChiLan1.0
INHBE
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21036,882,466 - 36,884,975 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11236,877,499 - 36,881,728 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01231,467,974 - 31,470,700 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11231,724,247 - 31,726,978 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1231,724,252 - 31,726,978 (-)EnsemblpanPan2panpan1.1
INHBE
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1101,558,876 - 1,563,370 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl101,559,770 - 1,562,885 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha101,622,273 - 1,626,266 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0101,568,055 - 1,572,048 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl101,568,174 - 1,572,796 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1101,546,151 - 1,550,142 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0101,787,658 - 1,791,648 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0101,912,977 - 1,916,971 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Inhbe
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494557,253,345 - 57,256,317 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366461,614,745 - 1,616,279 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366461,614,902 - 1,616,482 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
INHBE
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl522,732,516 - 22,734,083 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1522,732,774 - 22,734,716 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2524,808,794 - 24,811,612 (-)NCBISscrofa10.2Sscrofa10.2susScr3
INHBE
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11153,367,304 - 53,369,205 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1153,367,423 - 53,370,322 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037192,597,371 - 192,599,709 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Inhbe
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480210,493,576 - 10,499,565 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462480210,497,618 - 10,499,433 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Inhbe
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11205,785,301 - 205,786,632 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Inhbe
57 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:234
Count of miRNA genes:152
Interacting mature miRNAs:182
Transcripts:ENSRNOT00000010106
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72380760668807606Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74511390390113903Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72663805771638057Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72417947886817926Rat
10059605Kidm47Kidney mass QTL 472.910.05kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)74913799967614020Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)75170064396700643Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)731770293110435881Rat
1298525Cm1Cardiac mass QTL 12.7heart mass (VT:0007028)heart wet weight (CMO:0000069)756625161101625161Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73984590284845902Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73299870277998702Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73617876481178764Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)755498584105834451Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)763889858108889858Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74847504993475049Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73617876481178764Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72862457565788017Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)749682832115766396Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)762963207107963207Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)72154197786817926Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)763889858108889858Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)749682832115766396Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)749682832115766396Rat
2303582Gluco53Glucose level QTL 533blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)74860308793603087Rat
61439Cia8Collagen induced arthritis QTL 85.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)72718291472182914Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 7 26 64 79 75 59 38 59 3 211 87 9 41 50 40 16 4 4

Sequence


Ensembl Acc Id: ENSRNOT00000010106   ⟹   ENSRNOP00000010106
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl765,061,531 - 65,064,519 (-)Ensembl
mRatBN7.2 Ensembl763,176,219 - 63,179,172 (-)Ensembl
Rnor_6.0 Ensembl770,640,075 - 70,643,169 (-)Ensembl
RefSeq Acc Id: NM_031815   ⟹   NP_114003
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8765,061,531 - 65,064,519 (-)NCBI
mRatBN7.2763,176,221 - 63,179,209 (-)NCBI
Rnor_6.0770,641,423 - 70,642,848 (-)NCBI
Rnor_5.0770,815,702 - 70,817,127 (-)NCBI
RGSC_v3.4767,308,713 - 67,310,138 (-)RGD
Celera760,317,558 - 60,318,983 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_114003 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC36741 (Get FASTA)   NCBI Sequence Viewer  
  AAD30133 (Get FASTA)   NCBI Sequence Viewer  
  EDM16469 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000010106
GenBank Protein O88959 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_114003   ⟸   NM_031815
- Peptide Label: precursor
- UniProtKB: Q9R285 (UniProtKB/Swiss-Prot),   O88959 (UniProtKB/Swiss-Prot),   A0A0G2JSJ0 (UniProtKB/TrEMBL),   A6HQV3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000010106   ⟸   ENSRNOT00000010106
Protein Domains
TGF-beta family profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O88959-F1-model_v2 AlphaFold O88959 1-350 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695259
Promoter ID:EPDNEW_R5784
Type:initiation region
Name:Inhbe_1
Description:inhibin beta E subunit
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0770,643,074 - 70,643,134EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621196 AgrOrtholog
BioCyc Gene G2FUF-33749 BioCyc
Ensembl Genes ENSRNOG00000007601 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000010106 ENTREZGENE
Gene3D-CATH 2.10.90.10 UniProtKB/Swiss-Prot
InterPro Cystine-knot_cytokine UniProtKB/Swiss-Prot
  Inhibin_betaC UniProtKB/Swiss-Prot
  TGF-b_C UniProtKB/Swiss-Prot
  TGF-beta-rel UniProtKB/Swiss-Prot
  TGFb_CS UniProtKB/Swiss-Prot
KEGG Report rno:83711 UniProtKB/Swiss-Prot
NCBI Gene 83711 ENTREZGENE
PANTHER INHIBIN BETA E CHAIN UniProtKB/Swiss-Prot
  PTHR11848 UniProtKB/Swiss-Prot
Pfam TGF_beta UniProtKB/Swiss-Prot
PhenoGen Inhbe PhenoGen
PRINTS INHIBINBC UniProtKB/Swiss-Prot
PROSITE TGF_BETA_1 UniProtKB/Swiss-Prot
  TGF_BETA_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000007601 RatGTEx
SMART TGFB UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57501 UniProtKB/Swiss-Prot
UniProt A0A0G2JSJ0 ENTREZGENE, UniProtKB/TrEMBL
  A6HQV3 ENTREZGENE, UniProtKB/TrEMBL
  INHBE_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q9R285 ENTREZGENE
UniProt Secondary Q9R285 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-25 Inhbe  inhibin subunit beta E  Inhbe  inhibin beta E subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-06-01 Inhbe  inhibin beta E subunit  Inhbe  inhibin beta E  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Inhbe  inhibin beta E    activin beta E  Name updated 1299863 APPROVED
2002-08-07 Inhbe  activin beta E      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in hepatocytes 631972