Dnah11 (dynein, axonemal, heavy chain 11) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Dnah11 (dynein, axonemal, heavy chain 11) Rattus norvegicus
Analyze
Symbol: Dnah11
Name: dynein, axonemal, heavy chain 11
RGD ID: 621088
Description: Predicted to enable dynein intermediate chain binding activity; dynein light intermediate chain binding activity; and minus-end-directed microtubule motor activity. Predicted to be involved in cilium movement involved in cell motility and protein localization to motile cilium. Predicted to act upstream of or within several processes, including determination of left/right symmetry; flagellated sperm motility; and regulation of cilium beat frequency. Predicted to be located in 9+0 motile cilium and proximal portion of axoneme. Predicted to be part of dynein complex. Predicted to be active in 9+2 motile cilium and axoneme. Human ortholog(s) of this gene implicated in Kartagener syndrome and primary ciliary dyskinesia 7. Orthologous to human DNAH11 (dynein axonemal heavy chain 11); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Dnahc11; dynein axonemal heavy chain 11; dynein heavy chain 11, axonemal; dynein, axon, heavy chain 11; dynein, axonemal, heavy polypeptide 11
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Dnah11Tn(sb-T2/Bart3)2.293Mcwi  
Genetic Models: F344-Dnah11Tn(sb-T2/Bart3)2.293Mcwi
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86144,982,130 - 145,298,523 (-)NCBIGRCr8
mRatBN7.26138,839,175 - 139,155,554 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6138,839,177 - 139,155,536 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.06145,784,893 - 146,099,212 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6145,785,275 - 146,099,053 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06154,698,519 - 155,011,384 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46145,190,931 - 145,516,859 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16145,376,140 - 145,389,155 (-)NCBI
Celera6136,492,481 - 136,807,626 (-)NCBICelera
Cytogenetic Map6q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnah11RatKartagener syndrome susceptibilityISODNAH11 (Homo sapiens)734893DNA:nonsense mutation more ...RGD 
1 to 12 of 12 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnah11Ratcleft palate  ISODNAH11 (Homo sapiens)8554872ClinVar Annotator: match by term: Cleft palateClinVarPMID:24033266 more ...
Dnah11RatCognitive Dysfunction  ISODNAH11 (Homo sapiens)8554872ClinVar Annotator: match by term: Cognitive impairmentClinVarPMID:24033266 more ...
Dnah11Ratgenetic disease  ISODNAH11 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:28492532
Dnah11Rathypomyelinating leukodystrophy 5  ISODNAH11 (Homo sapiens)8554872ClinVar Annotator: match by term: Hypomyelination and Congenital CataractClinVarPMID:18022865 more ...
Dnah11Ratinfertility  ISODNAH11 (Homo sapiens)8554872ClinVar Annotator: match by term: InfertilityClinVarPMID:25741868 and PMID:28492532
Dnah11RatLaterality Defects, Autosomal Dominant  ISODNAH11 (Homo sapiens)8554872ClinVar Annotator: match by term: Laterality defects and autosomal dominantClinVarPMID:18022865 more ...
Dnah11Ratmale infertility  ISODNAH11 (Homo sapiens)8554872ClinVar Annotator: match by term: Male infertilityClinVarPMID:22184204 more ...
Dnah11Ratperiventricular leukomalacia  ISODNAH11 (Homo sapiens)8554872ClinVar Annotator: match by term: Periventricular leukomalaciaClinVarPMID:24033266 more ...
Dnah11Ratpleomorphic xanthoastrocytoma  ISODNAH11 (Homo sapiens)8554872ClinVar Annotator: match by term: Pleomorphic xanthoastrocytomaClinVarPMID:28299358
Dnah11Ratprimary ciliary dyskinesia  ISODNAH11 (Homo sapiens)8554872ClinVar Annotator: match by term: Primary ciliary dyskinesiaClinVarPMID:16199547 more ...
Dnah11Ratprimary ciliary dyskinesia 3  ISODNAH11 (Homo sapiens)8554872ClinVar Annotator: match by term: Primary ciliary dyskinesia 3ClinVar 
Dnah11Ratprimary ciliary dyskinesia 7  ISODNAH11 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:12142464 more ...
1 to 12 of 12 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnah11Ratautism spectrum disorder  ISODNAH11 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:35663546
Dnah11RatCoronary Disease  ISODNAH11 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:19060911
Dnah11RatDyslipidemias  ISODNAH11 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:19060911
Dnah11Ratprimary ciliary dyskinesia 7  ISODNAH11 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Dnah11RatWeight Gain  ISODNAH11 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:19030233
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnah11Ratatrioventricular septal defect  ISSDnah11 (Mus musculus)13592920OMIM:600309 more ...MouseDO 
Dnah11RatKartagener syndrome  ISSDnah11 (Mus musculus)13592920 MouseDO 
Dnah11Ratprimary ciliary dyskinesia 7  ISSDnah11 (Mus musculus)13592920OMIM:611884MouseDO 
Dnah11Ratvisceral heterotaxy  ISSDnah11 (Mus musculus)13592920OMIM:306955 more ...MouseDO 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnah11Ratprimary ciliary dyskinesia 7  ISODNAH11 (Homo sapiens)7240710 OMIM 

1 to 20 of 66 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnah11Rat1,2-dichloroethane decreases expressionISODnah11 (Mus musculus)6480464ethylene dichloride results in decreased expression of DNAH11 mRNACTDPMID:28960355
Dnah11Rat17beta-estradiol multiple interactionsISODNAH11 (Homo sapiens)6480464[Estradiol co-treated with TGFB1 protein] results in decreased expression of DNAH11 mRNACTDPMID:30165855
Dnah11Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISODNAH11 (Homo sapiens)6480464Tetrachlorodibenzodioxin affects the expression of DNAH11 mRNACTDPMID:22574217
Dnah11Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISODnah11 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of DNAH11 mRNACTDPMID:33956508
Dnah11Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of DNAH11 mRNACTDPMID:32109520
Dnah11Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISODnah11 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of DNAH11 mRNACTDPMID:26377647
Dnah11Rat2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expressionISODnah11 (Mus musculus)64804642 more ...CTDPMID:38648751
Dnah11Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISODNAH11 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of DNAH11 mRNACTDPMID:28628672
Dnah11Rat4,4'-sulfonyldiphenol multiple interactionsISODNAH11 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of DNAH11 mRNACTDPMID:28628672
Dnah11Rat4,4'-sulfonyldiphenol affects methylationISODnah11 (Mus musculus)6480464bisphenol S affects the methylation of DNAH11 geneCTDPMID:31683443
Dnah11Rat4,4'-sulfonyldiphenol increases methylationISODnah11 (Mus musculus)6480464bisphenol S results in increased methylation of DNAH11 exonCTDPMID:33297965
Dnah11Rat4-hydroxyphenyl retinamide increases expressionISODnah11 (Mus musculus)6480464Fenretinide results in increased expression of DNAH11 mRNACTDPMID:28973697
Dnah11Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of DNAH11 mRNACTDPMID:30047161
Dnah11Ratacrylamide decreases expressionEXP 6480464Acrylamide results in decreased expression of DNAH11 mRNACTDPMID:28959563
Dnah11Ratacrylamide decreases expressionISODNAH11 (Homo sapiens)6480464Acrylamide results in decreased expression of DNAH11 mRNACTDPMID:32763439
Dnah11Ratalpha-Zearalanol multiple interactionsEXP 6480464[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of DNAH11 mRNACTDPMID:35163327
Dnah11Ratamitrole decreases expressionEXP 6480464Amitrole results in decreased expression of DNAH11 mRNACTDPMID:30047161
Dnah11Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of DNAH11 mRNACTDPMID:16483693
Dnah11Ratarsenite(3-) increases expressionISODNAH11 (Homo sapiens)6480464arsenite results in increased expression of DNAH11 mRNACTDPMID:23974009
Dnah11Ratarsenite(3-) decreases methylationISODNAH11 (Homo sapiens)6480464arsenite results in decreased methylation of DNAH11 promoterCTDPMID:23974009

1 to 20 of 66 rows

Biological Process
1 to 16 of 16 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnah11Ratbiological_process  ND 159840704/2007: no relevant rat dataRGD 
Dnah11Ratcardiac septum morphogenesis acts_upstream_of_or_withinISODnah11 (Mus musculus)1624291MGI:4821828 PMID:27340223RGDPMID:27340223
Dnah11Ratcilium movement acts_upstream_of_or_withinISODnah11 (Mus musculus)1624291MGI:2152963 PMID:10556073RGDPMID:10556073
Dnah11Ratcilium movement involved in cell motility involved_inIBAFB:FBgn0001313 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Dnah11Ratdetermination of left/right asymmetry in nervous system acts_upstream_of_or_withinISODnah11 (Mus musculus)1624291MGI:1856917 PMID:18414654RGDPMID:18414654
Dnah11Ratdetermination of left/right symmetry acts_upstream_of_or_withinISODNAH11 (Homo sapiens)1624291 PMID:12142464 more ...RGDPMID:12142464 more ...
Dnah11Ratdetermination of left/right symmetry acts_upstream_of_or_withinISODnah11 (Mus musculus)1624291MGI:1856917 more ...RGDMGI:48750 more ...
Dnah11Ratepithelial cilium movement involved in determination of left/right asymmetry acts_upstream_of_or_withinISODnah11 (Mus musculus)1624291MGI:1856917 PMID:10549278 and PMID:22102620RGDPMID:10549278 and PMID:22102620
Dnah11Ratepithelial cilium movement involved in extracellular fluid movement acts_upstream_of_or_withinISODnah11 (Mus musculus)1624291MGI:1856917 more ...RGDPMID:22102620
Dnah11Ratflagellated sperm motility acts_upstream_of_or_withinISODNAH11 (Homo sapiens)1624291 PMID:18492703RGDPMID:18492703
Dnah11Ratflagellated sperm motility acts_upstream_of_or_withinISODnah11 (Mus musculus)1624291MGI:1856917 PMID:22102620RGDPMID:22102620
Dnah11Ratheart development acts_upstream_of_or_withinISODnah11 (Mus musculus)1624291 PMID:25807483RGDPMID:25807483
Dnah11Ratlearning or memory acts_upstream_of_or_withinISODnah11 (Mus musculus)1624291MGI:1856917 PMID:21103351RGDPMID:21103351
Dnah11Ratmicrotubule-based movement involved_inIEAInterPro:IPR004273 and InterPro:IPR0269831600115GO_REF:0000002InterProGO_REF:0000002
Dnah11Ratprotein localization to motile cilium involved_inISODNAH11 (Homo sapiens)1624291 PMID:33139725RGDPMID:33139725
Dnah11Ratregulation of cilium beat frequency acts_upstream_of_or_withinISODNAH11 (Homo sapiens)1624291 PMID:18022865 more ...RGDPMID:18022865 more ...
1 to 16 of 16 rows

Cellular Component
1 to 20 of 24 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnah11Rat9+0 motile cilium located_inISODnah11 (Mus musculus)1624291 PMID:26909801 and PMID:33347437RGDPMID:26909801 and PMID:33347437
Dnah11Rat9+2 motile cilium located_inISODNAH11 (Homo sapiens)1624291 PMID:26909801RGDPMID:26909801
Dnah11Rat9+2 motile cilium located_inISODnah11 (Mus musculus)1624291 PMID:26909801 and PMID:33347437RGDPMID:26909801 and PMID:33347437
Dnah11Rat9+2 motile cilium is_active_inIBAFB:FBgn0001313 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Dnah11Rat9+2 motile cilium located_inISODNAH11 (Sus scrofa)1624291 PMID:33139725RGDPMID:33139725
Dnah11Rataxoneme located_inISODNAH11 (Homo sapiens)1624291 PMID:31178125RGDPMID:31178125
Dnah11Rataxoneme located_inISODnah11 (Mus musculus)1624291 PMID:26909801 and PMID:33347437RGDPMID:26909801 and PMID:33347437
Dnah11Rataxoneme is_active_inIBAMGI:1100864 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Dnah11Rataxoneme located_inISODNAH11 (Sus scrofa)1624291 PMID:33139725RGDPMID:33139725
Dnah11Ratcell projection located_inIEAUniProtKB-KW:KW-09661600115GO_REF:0000043UniProtGO_REF:0000043
Dnah11Ratcilium located_inISODnah11 (Mus musculus)1624291 PMID:31887266RGDPMID:31887266
Dnah11Ratcilium located_inIEAUniProtKB-KW:KW-09691600115GO_REF:0000043UniProtGO_REF:0000043
Dnah11Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Dnah11Ratcytoskeleton located_inIEAUniProtKB-KW:KW-02061600115GO_REF:0000043UniProtGO_REF:0000043
Dnah11Ratdynein complex part_ofIBAFB:FBgn0261797 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Dnah11Ratdynein complex part_ofIEAUniProtKB-KW:KW-02431600115GO_REF:0000043UniProtGO_REF:0000043
Dnah11Ratdynein complex part_ofIEAInterPro:IPR004273 and InterPro:IPR0269831600115GO_REF:0000002InterProGO_REF:0000002
Dnah11Ratextracellular region located_inIEAGO:00033511600115GO_REF:0000108GOCGO_REF:0000108
Dnah11Ratmicrotubule located_inIEAUniProtKB-KW:KW-04931600115GO_REF:0000043UniProtGO_REF:0000043
Dnah11Ratmotile cilium located_inISODNAH11 (Homo sapiens)1624291 PMID:31178125RGDPMID:31178125
1 to 20 of 24 rows

Molecular Function
1 to 11 of 11 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnah11RatATP binding enablesIEAUniProtKB-KW:KW-00671600115GO_REF:0000043UniProtGO_REF:0000043
Dnah11RatATP binding enablesIEAInterPro:IPR0356991600115GO_REF:0000002InterProGO_REF:0000002
Dnah11RatATP hydrolysis activity enablesIEAInterPro:IPR0035931600115GO_REF:0000002InterProGO_REF:0000002
Dnah11Ratdynein intermediate chain binding enablesIBAPANTHER:PTN000743491 and dictyBase:DDB_G02763551600115GO_REF:0000033GO_CentralGO_REF:0000033
Dnah11Ratdynein intermediate chain binding enablesIEAInterPro:IPR0269831600115GO_REF:0000002InterProGO_REF:0000002
Dnah11Ratdynein light intermediate chain binding enablesIBAMGI:103147 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Dnah11Ratdynein light intermediate chain binding enablesIEAInterPro:IPR0269831600115GO_REF:0000002InterProGO_REF:0000002
Dnah11Ratminus-end-directed microtubule motor activity enablesIBAPANTHER:PTN000743491 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Dnah11Ratminus-end-directed microtubule motor activity enablesIEAInterPro:IPR0042731600115GO_REF:0000002InterProGO_REF:0000002
Dnah11Ratnucleotide binding enablesIEAUniProtKB-KW:KW-05471600115GO_REF:0000043UniProtGO_REF:0000043
Dnah11Ratprotein binding enablesISODNAH11 (Sus scrofa)1624291UniProtKB:A0A480NP79 and PMID:33139725RGDPMID:33139725
1 to 11 of 11 rows


1 to 9 of 9 rows
#
Reference Title
Reference Citation
1. Mutations in the DNAH11 (axonemal heavy chain dynein type 11) gene cause one form of situs inversus totalis and most likely primary ciliary dyskinesia. Bartoloni L, etal., Proc Natl Acad Sci U S A 2002 Aug 6;99(16):10282-6. Epub 2002 Jul 25.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. Identification and molecular evolution of new dynein-like protein sequences in rat brain. Tanaka Y, etal., J Cell Sci 1995 May;108 ( Pt 5):1883-93.
1 to 9 of 9 rows
PMID:9353118   PMID:10549278   PMID:10556073   PMID:18022865   PMID:18414654   PMID:18492703   PMID:21103351   PMID:22102620   PMID:22184204   PMID:22499950   PMID:25807483   PMID:26909801  
PMID:27340223   PMID:31178125  



Dnah11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86144,982,130 - 145,298,523 (-)NCBIGRCr8
mRatBN7.26138,839,175 - 139,155,554 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6138,839,177 - 139,155,536 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.06145,784,893 - 146,099,212 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6145,785,275 - 146,099,053 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06154,698,519 - 155,011,384 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46145,190,931 - 145,516,859 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16145,376,140 - 145,389,155 (-)NCBI
Celera6136,492,481 - 136,807,626 (-)NCBICelera
Cytogenetic Map6q33NCBI
DNAH11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38721,543,039 - 21,901,839 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl721,543,039 - 21,901,839 (+)EnsemblGRCh38hg38GRCh38
GRCh37721,582,657 - 21,941,457 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36721,549,358 - 21,907,982 (+)NCBINCBI36Build 36hg18NCBI36
Build 34721,356,072 - 21,714,701NCBI
Celera721,568,334 - 21,927,147 (+)NCBICelera
Cytogenetic Map7p15.3NCBI
HuRef721,468,066 - 21,826,836 (+)NCBIHuRef
CHM1_1721,583,500 - 21,941,892 (+)NCBICHM1_1
T2T-CHM13v2.0721,679,184 - 22,038,139 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2721,634,147 - 21,992,554 (+)NCBI
Dnah11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912117,841,717 - 118,162,778 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12117,841,717 - 118,162,778 (-)EnsemblGRCm39 Ensembl
GRCm3812117,877,982 - 118,199,043 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12117,877,982 - 118,199,043 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712119,116,455 - 119,437,516 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612112,081,403 - 112,243,674 (-)NCBIMGSCv36mm8
MGSCv3612118,322,088 - 118,643,145 (-)NCBIMGSCv36mm8
Cytogenetic Map12F2NCBI
cM Map1263.25NCBI
Dnah11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541024,044,886 - 24,352,626 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541024,045,333 - 24,352,626 (+)NCBIChiLan1.0ChiLan1.0
DNAH11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2626,407,257 - 26,765,415 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1774,731,984 - 75,089,431 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0722,228,345 - 22,585,681 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1721,540,932 - 21,897,485 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl721,540,932 - 21,897,485 (+)Ensemblpanpan1.1panPan2
DNAH11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11435,468,080 - 35,784,621 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1435,468,154 - 35,784,806 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1435,010,233 - 35,326,619 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01435,391,909 - 35,710,339 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1435,391,935 - 35,710,334 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11435,511,481 - 35,830,033 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01435,211,138 - 35,527,954 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01435,544,474 - 35,863,246 (+)NCBIUU_Cfam_GSD_1.0
Dnah11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511879,695,026 - 80,008,043 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365467,370,381 - 7,681,020 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365467,370,180 - 7,681,835 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNAH11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl990,423,092 - 90,768,353 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1990,420,044 - 90,768,327 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2999,840,344 - 100,218,083 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DNAH11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12136,350,606 - 36,722,018 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2136,350,707 - 36,720,511 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604267,858,273 - 68,228,833 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dnah11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247398,811,082 - 9,135,815 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247398,810,127 - 9,136,044 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Dnah11
2100 total Variants

Predicted Target Of
Summary Value
Count of predictions:28
Count of miRNA genes:28
Interacting mature miRNAs:28
Transcripts:ENSRNOT00000007233
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 9 of 9 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)6122549046140994061Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6112636280140994061Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6122549046140286318Rat

1 to 9 of 9 rows
D6Rat3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26138,922,743 - 138,922,889 (+)MAPPERmRatBN7.2
Rnor_6.06145,868,453 - 145,868,598NCBIRnor6.0
Rnor_5.06154,781,896 - 154,782,041UniSTSRnor5.0
RGSC_v3.46145,279,033 - 145,279,536RGDRGSC3.4
RGSC_v3.46145,279,292 - 145,279,437UniSTSRGSC3.4
RGSC_v3.16145,285,479 - 145,285,624RGD
Celera6136,575,859 - 136,576,004UniSTS
RH 3.4 Map6907.6RGD
RH 3.4 Map6907.6UniSTS
RH 2.0 Map61234.2RGD
SHRSP x BN Map683.9998RGD
Cytogenetic Map6q33UniSTS
RH131860  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26138,973,184 - 138,973,382 (+)MAPPERmRatBN7.2
Rnor_6.06145,918,851 - 145,919,048NCBIRnor6.0
Rnor_5.06154,832,365 - 154,832,562UniSTSRnor5.0
RGSC_v3.46145,330,406 - 145,330,603UniSTSRGSC3.4
Celera6136,625,801 - 136,625,998UniSTS
RH 3.4 Map6905.1UniSTS
Cytogenetic Map6q33UniSTS
AU049492  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr86145,010,550 - 145,010,776 (+)Marker Load Pipeline
mRatBN7.26138,867,600 - 138,867,826 (+)MAPPERmRatBN7.2
Rnor_6.06145,813,312 - 145,813,537NCBIRnor6.0
Rnor_5.06154,726,555 - 154,726,780UniSTSRnor5.0
RGSC_v3.46145,218,632 - 145,218,857UniSTSRGSC3.4
Cytogenetic Map6q33UniSTS


This gene Dnah11 is modified in the following models/strains:
F344-Dnah11Tn(sb-T2/Bart3)2.293Mcwi    




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 72 71 40 25 40 6 199 97 93 45 60 31


1 to 23 of 23 rows
RefSeq Transcripts XM_001061747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039078101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC118412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D26503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 23 of 23 rows

Ensembl Acc Id: ENSRNOT00000007233   ⟹   ENSRNOP00000007233
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6138,839,177 - 139,155,536 (-)Ensembl
Rnor_6.0 Ensembl6145,785,275 - 146,099,053 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000102541   ⟹   ENSRNOP00000089399
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6138,839,177 - 139,155,536 (-)Ensembl
RefSeq Acc Id: XM_039078091   ⟹   XP_038934019
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86144,982,130 - 145,298,523 (-)NCBI
mRatBN7.26138,839,175 - 139,155,553 (-)NCBI
RefSeq Acc Id: XM_039078092   ⟹   XP_038934020
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86144,982,130 - 145,298,523 (-)NCBI
mRatBN7.26138,839,175 - 139,155,553 (-)NCBI
RefSeq Acc Id: XM_039078093   ⟹   XP_038934021
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86144,982,130 - 145,298,523 (-)NCBI
mRatBN7.26138,839,175 - 139,155,553 (-)NCBI
RefSeq Acc Id: XM_039078094   ⟹   XP_038934022
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86144,982,130 - 145,298,523 (-)NCBI
mRatBN7.26138,839,175 - 139,155,553 (-)NCBI
RefSeq Acc Id: XM_039078095   ⟹   XP_038934023
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86144,982,130 - 145,296,180 (-)NCBI
mRatBN7.26138,839,175 - 139,153,214 (-)NCBI
RefSeq Acc Id: XM_039078097   ⟹   XP_038934025
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86144,982,130 - 145,290,205 (-)NCBI
mRatBN7.26138,839,175 - 139,147,236 (-)NCBI
RefSeq Acc Id: XM_039078099   ⟹   XP_038934027
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86144,982,130 - 145,213,671 (-)NCBI
mRatBN7.26138,839,175 - 139,070,703 (-)NCBI
RefSeq Acc Id: XM_039078100   ⟹   XP_038934028
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86144,982,130 - 145,200,647 (-)NCBI
mRatBN7.26138,839,175 - 139,057,679 (-)NCBI
RefSeq Acc Id: XM_039078101   ⟹   XP_038934029
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86144,982,130 - 145,176,988 (-)NCBI
mRatBN7.26138,839,175 - 139,033,329 (-)NCBI
RefSeq Acc Id: XM_063262808   ⟹   XP_063118878
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86144,982,130 - 145,298,523 (-)NCBI
RefSeq Acc Id: XM_063262809   ⟹   XP_063118879
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86144,982,130 - 145,219,855 (-)NCBI
RefSeq Acc Id: XM_063262810   ⟹   XP_063118880
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86144,982,130 - 145,298,523 (-)NCBI
1 to 5 of 14 rows
1 to 5 of 14 rows
Ensembl Acc Id: ENSRNOP00000007233   ⟸   ENSRNOT00000007233
RefSeq Acc Id: XP_038934022   ⟸   XM_039078094
- Peptide Label: isoform X5
- UniProtKB: E9PU24 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038934021   ⟸   XM_039078093
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038934020   ⟸   XM_039078092
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038934019   ⟸   XM_039078091
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GH84 (UniProtKB/TrEMBL)
AAA+ ATPase   Dynein heavy chain 3 AAA+ lid   Dynein heavy chain AAA 5 extension   Dynein heavy chain AAA lid   Dynein heavy chain AAA module D4   Dynein heavy chain ATP-binding dynein motor region   Dynein heavy chain C-terminal   Dynein heavy chain coiled coil stalk   Dynein heavy chain region D6 P-loop


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 40 of 62 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-35475 BioCyc
Ensembl Genes ENSRNOG00000005451 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000007233 ENTREZGENE
  ENSRNOT00000007233.7 UniProtKB/TrEMBL
  ENSRNOT00000102541.1 UniProtKB/TrEMBL
  ENSRNOT00000152917 ENTREZGENE
  ENSRNOT00000170678 ENTREZGENE
Gene3D-CATH 1.10.287.2620 UniProtKB/TrEMBL
  1.10.472.130 UniProtKB/TrEMBL
  1.10.8.1220 UniProtKB/TrEMBL
  1.10.8.710 UniProtKB/TrEMBL
  1.10.8.720 UniProtKB/TrEMBL
  1.20.1270.280 UniProtKB/TrEMBL
  1.20.140.100 UniProtKB/TrEMBL
  1.20.58.1120 UniProtKB/TrEMBL
  1.20.920.20 UniProtKB/TrEMBL
  1.20.920.30 UniProtKB/TrEMBL
  3.10.490.20 UniProtKB/TrEMBL
  3.20.180.20 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
  6.10.140.1060 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  AAA_6 UniProtKB/TrEMBL
  AAA_lid_11 UniProtKB/TrEMBL
  AAA_lid_11_sf UniProtKB/TrEMBL
  DHC_D5 UniProtKB/TrEMBL
  DHC_fam UniProtKB/TrEMBL
  DNAH3_AAA_lid_1 UniProtKB/TrEMBL
  Dynein_2_C UniProtKB/TrEMBL
  Dynein_2_N UniProtKB/TrEMBL
  Dynein_AAA1S UniProtKB/TrEMBL
  Dynein_AAA5_ext UniProtKB/TrEMBL
  Dynein_C UniProtKB/TrEMBL
  Dynein_C_barrel UniProtKB/TrEMBL
  Dynein_HC_stalk UniProtKB/TrEMBL
  Dynein_heavy_chain_D4_dom UniProtKB/TrEMBL
  Dynein_heavy_dom UniProtKB/TrEMBL
  Dynein_heavy_dom-1 UniProtKB/TrEMBL
  Dynein_heavy_dom-2 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
1 to 40 of 62 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-17 Dnah11  dynein, axonemal, heavy chain 11  Dnahc11  dynein, axonemal, heavy chain 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-10 Dnahc11  dynein, axonemal, heavy chain 11  Dnah11  dynein, axonemal, heavy chain 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-22 Dnah11  dynein, axonemal, heavy chain 11  Dnah11  dynein, axonemal, heavy polypeptide 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Dnah11  dynein, axonemal, heavy polypeptide 11  Dnahc11  dynein, axon, heavy chain 11  Symbol and Name updated 1299863 APPROVED
2002-08-07 Dnahc11  dynein, axon, heavy chain 11      Symbol and Name status set to provisional 70820 PROVISIONAL