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Gene: Iars1 (isoleucyl-tRNA synthetase 1) Rattus norvegicus

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Symbol:

Iars1

Name:

isoleucyl-tRNA synthetase 1

RGD ID:

621022

Description:

Predicted to enable GTPase binding activity and isoleucine-tRNA ligase activity. Predicted to be involved in isoleucyl-tRNA aminoacylation. Predicted to be located in cytoplasm. Predicted to be part of aminoacyl-tRNA synthetase multienzyme complex. Orthologous to human IARS1 (isoleucyl-tRNA synthetase 1); PARTICIPATES IN aminoacyl-tRNA biosynthetic pathway; valine, leucine and isoleucine biosynthetic pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Iars; Iarsl; isoleucine tRNA synthetase; isoleucine--tRNA ligase, cytoplasmic; isoleucine--tRNA ligase, cytoplasmic-like; isoleucine-tRNA synthetase; isoleucine-tRNA synthetase-like; isoleucyl tRNA synthetase; isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase, cytoplasmic; LOC103690033; LOC306804

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	IARS1 (isoleucyl-tRNA synthetase 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Iars1 (isoleucyl-tRNA synthetase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Iars1 (isoleucyl-tRNA synthetase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	IARS1 (isoleucyl-tRNA synthetase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	IARS1 (isoleucyl-tRNA synthetase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Iars1 (isoleucyl-tRNA synthetase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	IARS1 (isoleucyl-tRNA synthetase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	IARS1 (isoleucyl-tRNA synthetase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Iars1 (isoleucyl-tRNA synthetase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Iars1 (isoleucyl-tRNA synthetase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	NEFH (neurofilament heavy chain)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	IARS1 (isoleucyl-tRNA synthetase 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Iars1 (isoleucyl-tRNA synthetase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	iars (isoleucyl-tRNA synthetase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	ILS1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	IleRS	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	iars-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	iars1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	iars1	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	15,147,357 - 15,193,716 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	17	15,147,357 - 15,193,652 (-)	Ensembl				GRCr8
mRatBN7.2	17	14,940,919 - 14,987,277 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	14,940,924 - 14,987,237 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	17	14,827,845 - 14,874,168 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	16,432,900 - 16,479,224 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	14,754,642 - 14,800,962 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	15,356,016 - 15,402,680 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	15,355,529 - 15,402,649 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	17	16,604,188 - 16,614,960 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	17	17,414,466 - 17,461,119 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	17	20,895,852 - 20,942,180 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	17	14,672,657 - 14,718,804 (-)	NCBI		Celera
RGSC_v3.1	17	20,895,861 - 20,937,378 (-)	NCBI
Cytogenetic Map	17	p14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Developmental Disabilities (ISO)

genetic disease (ISO)

GROWTH RETARDATION, INTELLECTUAL DEVELOPMENTAL DISORDER, HYPOTONIA, AND HEPATOPATHY (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

1-chloro-2,4-dinitrobenzene (ISO)

1-naphthyl isothiocyanate (EXP)

1-nitropyrene (ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dimethoxyphenol (ISO)

2,6-dinitrotoluene (EXP)

3-chloropropane-1,2-diol (EXP)

4,4'-sulfonyldiphenol (ISO)

4-amino-2,6-dinitrotoluene (EXP)

acetylsalicylic acid (ISO)

aconitine (EXP)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amphetamine (EXP)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

bisphenol F (ISO)

buspirone (EXP)

cadmium dichloride (EXP,ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chloroacetaldehyde (ISO)

chlorpyrifos (ISO)

chromium(6+) (ISO)

cidofovir anhydrous (ISO)

cisplatin (ISO)

clodronic acid (ISO)

cobalt dichloride (ISO)

Cuprizon (EXP)

cyclosporin A (EXP,ISO)

diarsenic trioxide (ISO)

diclofenac (ISO)

dioxygen (ISO)

elemental selenium (ISO)

enzyme inhibitor (ISO)

epoxiconazole (ISO)

fenofibrate (EXP,ISO)

fenthion (ISO)

flutamide (EXP)

folic acid (ISO)

FR900359 (ISO)

fulvestrant (ISO)

furfural (ISO)

gentamycin (EXP)

ibuprofen (EXP,ISO)

ifosfamide (ISO)

ivermectin (ISO)

L-ascorbic acid (ISO)

lead diacetate (EXP)

lead(0) (ISO)

menadione (ISO)

mercury dichloride (EXP)

metformin (EXP)

methapyrilene (EXP)

methidathion (ISO)

methoxychlor (EXP)

methyl methanesulfonate (ISO)

methylparaben (ISO)

N(4)-hydroxycytidine (ISO)

N-methyl-4-phenylpyridinium (EXP,ISO)

nefazodone (EXP)

nitrates (ISO)

paracetamol (ISO)

paraquat (EXP)

perfluorononanoic acid (ISO)

quercetin (ISO)

resveratrol (ISO)

SB 431542 (ISO)

selenium atom (ISO)

sodium arsenite (ISO)

sodium chloride (ISO)

sunitinib (ISO)

tetrachloroethene (ISO)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

trimellitic anhydride (ISO)

triptonide (ISO)

trovafloxacin (ISO)

tunicamycin (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

aminoacyl-tRNA metabolism involved in translational fidelity (IEA)

isoleucyl-tRNA aminoacylation (IBA,IEA,ISO)

translation (IEA)

tRNA aminoacylation for protein translation (IEA)

Cellular Component

aminoacyl-tRNA synthetase multienzyme complex (IEA,ISO)

cytoplasm (ISO)

cytosol (IEA,ISO)

Molecular Function

aminoacyl-tRNA deacylase activity (IEA)

aminoacyl-tRNA ligase activity (IEA)

ATP binding (IEA)

GTPase binding (ISO)

isoleucine-tRNA ligase activity (IBA,IEA,ISO)

ligase activity (IEA)

nucleotide binding (IEA)

protein binding (ISO)

tRNA binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

aminoacyl-tRNA biosynthetic pathway (IEA)

valine, leucine and isoleucine biosynthetic pathway (IEA)

External Pathway Database Links

KEGG Pathway

Valine, leucine and isoleucine biosynthesis

References

References - curated

#	Reference Title	Reference Citation
1.	A systematic analysis of 40 random genes in cultured vascular smooth muscle subtypes reveals a heterogeneity of gene expression and identifies the tight junction gene zonula occludens 2 as a marker of epithelioid "pup" smooth muscle cells and a participant in carotid neointimal formation.	Adams LD, etal., Arterioscler Thromb Vasc Biol 1999 Nov;19(11):2600-8.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
4.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
5.	GOA pipeline	RGD automated data pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8052601	PMID:12060739	PMID:12477932	PMID:16210410	PMID:19131329	PMID:19289464	PMID:19946888	PMID:20458337	PMID:22424946	PMID:24337748	PMID:33450132

Genomics

Comparative Map Data

Iars1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	15,147,357 - 15,193,716 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	17	15,147,357 - 15,193,652 (-)	Ensembl				GRCr8
mRatBN7.2	17	14,940,919 - 14,987,277 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	14,940,924 - 14,987,237 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	17	14,827,845 - 14,874,168 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	16,432,900 - 16,479,224 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	14,754,642 - 14,800,962 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	15,356,016 - 15,402,680 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	15,355,529 - 15,402,649 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	17	16,604,188 - 16,614,960 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	17	17,414,466 - 17,461,119 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	17	20,895,852 - 20,942,180 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	17	14,672,657 - 14,718,804 (-)	NCBI		Celera
RGSC_v3.1	17	20,895,861 - 20,937,378 (-)	NCBI
Cytogenetic Map	17	p14	NCBI

IARS1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	92,210,207 - 92,293,697 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	92,210,207 - 92,293,854 (-)	Ensembl			hg38	GRCh38
GRCh37	9	94,972,489 - 95,055,979 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	94,012,446 - 94,095,859 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	9	92,052,179 - 92,135,522	NCBI
Celera	9	65,408,928 - 65,492,347 (-)	NCBI		Celera
Cytogenetic Map	9	q22.31	NCBI
HuRef	9	64,650,352 - 64,733,811 (-)	NCBI		HuRef
CHM1_1	9	95,118,853 - 95,202,471 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	104,376,735 - 104,460,226 (-)	NCBI		T2T-CHM13v2.0

Iars1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	49,835,606 - 49,887,743 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	49,835,576 - 49,887,743 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	13	49,682,130 - 49,734,267 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	49,682,100 - 49,734,267 (+)	Ensembl			mm10	GRCm38
MGSCv37	13	49,777,499 - 49,829,636 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	13	49,694,081 - 49,746,194 (+)	NCBI		MGSCv36	mm8
Celera	13	50,772,786 - 50,823,970 (+)	NCBI		Celera
Cytogenetic Map	13	A5	NCBI
cM Map	13	25.38	NCBI

Iars1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955515	5,498,231 - 5,557,629 (+)	Ensembl
ChiLan1.0	NW_004955515	5,506,064 - 5,558,075 (+)	NCBI	ChiLan1.0	ChiLan1.0

IARS1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	47,136,048 - 47,219,577 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	47,138,434 - 47,221,967 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	63,332,030 - 63,415,567 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	91,406,008 - 91,489,167 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	91,406,008 - 91,489,167 (-)	Ensembl			panPan2	panpan1.1

IARS1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	99,045,023 - 99,113,865 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	99,045,102 - 99,113,620 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	99,438,844 - 99,507,644 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	99,662,000 - 99,730,810 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	99,662,052 - 99,730,810 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	99,274,953 - 99,343,693 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	99,010,147 - 99,079,155 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	99,766,929 - 99,835,896 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Iars1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	7,672,824 - 7,732,017 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936487	1,886,552 - 1,948,498 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936487	1,889,428 - 1,948,447 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IARS1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	41,945,770 - 42,022,760 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	3	41,945,846 - 42,022,610 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	42,962,905 - 43,014,138 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IARS1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	102,745,155 - 102,819,638 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	102,744,569 - 102,819,603 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666038	91,017,103 - 91,091,888 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Iars1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624868	4,063,002 - 4,168,715 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624868	4,062,938 - 4,168,712 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Iars1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	14	68,653,047 - 68,700,058 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Iars1
221 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	300
Count of miRNA genes:	183
Interacting mature miRNAs:	201
Transcripts:	ENSRNOT00000019862
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354581	Bp247	Blood pressure QTL 247	4.5		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	17	1	43999106	Rat
2300002	Iddm36	Insulin dependent diabetes mellitus QTL 36	1.98		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	17	9266755	40968173	Rat
2293664	Bmd28	Bone mineral density QTL 28	5.1	0.0001	femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	17	4360057	27233623	Rat
8552966	Pigfal18	Plasma insulin-like growth factor 1 level QTL 18	8.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	17	12860942	57860942	Rat
1300123	Bp194	Blood pressure QTL 194	2.82		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	2120843	42054133	Rat
1582224	Epfw4	Epididymal fat weight QTL 4	3.5	0.0058	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	17	9206505	23859062	Rat
1582225	Bw67	Body weight QTL 67	6.2	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	17	9206505	23859062	Rat
2302377	Scl61	Serum cholesterol level QTL 61	4.36		blood HDL cholesterol amount (VT:0000184)	serum high density lipoprotein cholesterol level (CMO:0000361)	17	6221998	58177198	Rat
1582226	Bw64	Body weight QTL 64	4.2	0.0017	body mass (VT:0001259)	body weight (CMO:0000012)	17	9206505	23859062	Rat
9589151	Insul30	Insulin level QTL 30	8.82	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	17	12860942	57860942	Rat
10401807	Kidm52	Kidney mass QTL 52			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	17	1	31706603	Rat
10054088	Scort28	Serum corticosterone level QTL 28	2.04	0.0102	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	17	4733534	49733534	Rat
9589057	Scfw6	Subcutaneous fat weight QTL 6	8.62	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	17	12860942	57860942	Rat
1582208	Kidm32	Kidney mass QTL 32	3.9	0.0018	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	17	9206505	23859062	Rat
9590154	Scort9	Serum corticosterone level QTL 9	23.57	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	17	12860942	57860942	Rat
9590088	Insglur7	Insulin/glucose ratio QTL 7	20.38	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	17	12860942	57860942	Rat
1549900	Iddm20	Insulin dependent diabetes mellitus QTL 20	3.7		pancreas integrity trait (VT:0010560)	percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)	17	1	22181410	Rat
2317053	Aia25	Adjuvant induced arthritis QTL 25	2.69		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	17	10604694	55604694	Rat
1354613	Kidm14	Kidney mass QTL 14	6.2		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	17	1	36045694	Rat
7411666	Foco31	Food consumption QTL 31	11.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	17	12860942	57860942	Rat
2324619	Coatc4	Coat color QTL 4		0.001	coat/hair pigmentation trait (VT:0010463)	pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)	17	1	21499218	Rat
2303627	Vencon8	Ventilatory control QTL 8		0.001	respiration trait (VT:0001943)	tidal volume (CMO:0000222)	17	4733534	49733534	Rat
1581553	Pur14	Proteinuria QTL 14	5.3	0.0001	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	17	7985243	16523460	Rat
70184	BpQTLcluster14	Blood pressure QTL cluster 14	3.38		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	17	8574342	32199534	Rat
1582258	Bw76	Body weight QTL 76	4.6	0.0005	body mass (VT:0001259)	body weight (CMO:0000012)	17	9206505	23859062	Rat
631207	Niddm41	Non-insulin dependent diabetes mellitus QTL 41			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	17	1	38037084	Rat
1582199	Insul5	Insulin level QTL 5	3.4	0.0119	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	17	9206505	23859062	Rat
1354662	Rf49	Renal function QTL 49	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	17	1	43999106	Rat
2293648	Bmd31	Bone mineral density QTL 31	4.5	0.0001	femur size trait (VT:1000369)	femoral neck cortical cross-sectional area (CMO:0001702)	17	4360057	27233623	Rat
1354658	Spl8	Serum phospholipid level QTL 8	3.8		blood VLDL phospholipid amount (VT:0010507)	blood very low density lipoprotein phospholipid level (CMO:0001571)	17	1	43999106	Rat
1641902	Colcr7	Colorectal carcinoma resistance QTL 7	3.35	0.0044	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	17	2120843	22087569	Rat
1582241	Bw70	Body weight QTL 70	4.6	0.0003	body mass (VT:0001259)	body weight (CMO:0000012)	17	9206505	23859062	Rat
1582245	Bw73	Body weight QTL 73	4.6	0.0004	body mass (VT:0001259)	body weight (CMO:0000012)	17	9206505	23859062	Rat
9590316	Scort21	Serum corticosterone level QTL 21	4.75	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	17	1	22877318	Rat

Markers in Region

RH141803

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	17	14,990,604 - 14,990,815 (+)	MAPPER	mRatBN7.2
Rnor_6.0	17	15,406,019 - 15,406,229	NCBI	Rnor6.0
Rnor_6.0	17	14,565,982 - 14,566,192	NCBI	Rnor6.0
Rnor_5.0	17	17,464,469 - 17,464,679	UniSTS	Rnor5.0
Rnor_5.0	17	16,618,303 - 16,618,513	UniSTS	Rnor5.0
RGSC_v3.4	17	20,945,568 - 20,945,778	UniSTS	RGSC3.4
Celera	17	14,722,192 - 14,722,402	UniSTS
RH 3.4 Map	17	157.3	UniSTS
Cytogenetic Map	17	p14	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	164	91	90	59	92	59	6	356	192	11	143	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001100572	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006253706	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008771533	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063276354	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC091369	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473977	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000019862 ⟹ ENSRNOP00000019862

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	15,147,357 - 15,193,652 (-)	Ensembl
mRatBN7.2 Ensembl	17	14,940,924 - 14,987,237 (-)	Ensembl
Rnor_6.0 Ensembl	17	15,356,016 - 15,402,631 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000078166 ⟹ ENSRNOP00000071046

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	17	14,940,924 - 14,987,237 (-)	Ensembl
Rnor_6.0 Ensembl	17	14,541,949 - 14,557,792 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000086344 ⟹ ENSRNOP00000069534

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	17	14,940,926 - 14,987,237 (-)	Ensembl
Rnor_6.0 Ensembl	17	15,355,529 - 15,398,988 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093637 ⟹ ENSRNOP00000076307

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	17	14,940,926 - 14,987,237 (-)	Ensembl
Rnor_6.0 Ensembl	17	15,356,019 - 15,402,649 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000101044 ⟹ ENSRNOP00000085677

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	17	14,941,664 - 14,987,237 (-)	Ensembl

RefSeq Acc Id:

NM_001100572 ⟹ NP_001094042

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	15,147,357 - 15,193,652 (-)	NCBI
mRatBN7.2	17	14,940,919 - 14,987,217 (-)	NCBI
Rnor_6.0	17	15,356,016 - 15,402,631 (-)	NCBI
Rnor_5.0	17	17,414,466 - 17,461,119 (-)	NCBI
RGSC_v3.4	17	20,895,852 - 20,942,180 (-)	RGD
Celera	17	14,672,657 - 14,718,804 (-)	NCBI

Sequence:

show sequence

GTGGTCGCAGTCTGCAACCTGAGCTTGCTCACCTCAGGGTTCCCAGGTGAGCCGCACCCTCCGC
CCTTCCGGGCCTCAGAGCGAGGCCTGCCGGTGTAACTATCTGTGGATAGCACCAGGCGGTGAAA
AAGGAGCACGCTGATTCCTTCCGTGAGTGAGCTGCGGGCACAGAGCTATTTCCACAGAGCCTTC
GTGGAGGGAGACAACAGAATGGTTCAACAAGTTCCGGAAAACATCAGCTTTCCTGCTGAAGAAG
AAAAAATCTTACAGTTCTGGTCCAAATACAACTGTTTCCAGGAATGCCTAAAGCAGTCAAAGCT
CAGGCCAAAGTTTACCTTCTATGATGGGCCTCCCTTCGCTACTGGACTGCCTCACTACGGACAC
ATACTTGCGGGGACAATTAAAGATATAGTTACAAGATACGCTCACCAGAGCGGGTTTCACGTCG
ACAGAAGATTCGGGTGGGATTGTCATGGCTTACCTGTGGAGTACGAGATTGACAAGACCCTGGG
GATCAAAGGGCCAGAGGACGTGGCCAAGATGGGGATCGCAGAGTACAACAAGCAGTGCCGAGCT
ATTGTGATGAGGTACTCCGCCGAGTGGAAGTCTACTGTTACCAGGCTTGGCCGATGGATCGACT
TTGACAATGACTACAAAACCCTGTACCCACAATTCATGGAATCAGTCTGGTGGGTCTTCAAGCA
GCTGTATGACAAAGGCCTCGTGTACAGAGGCGTGAAAGTCATGCCCTTCTCCACCGCGTGTGGA
ACTCCACTCTCCAACTTCGAGTCGAACCAGAATTACAAGGACGTTCAGGACCCTTCAGTATTTG
TAACGTTCCCTTTGGAGGAAGATGAAAACACATCCTTAGTTGCTTGGACAACCACTCCGTGGAC
CCTACCCAGTAACCTTGCGCTATGTGTCAATCCAGAAATACAGTATGTGAAGATCAAAGACGTT
TCCAGGGGGAAGTTGTTCATTTTGATGGAAGCCAGATTGTCGGCCCTCTATAAACAAGAGAGCG
ACTATGAGATCCTTGAAAGGTTTCCTGGTGCCTCTCTCAAAGGCAAGAAATACAAGCCGTTGTT
TGACTACTTTATTAAGTGTAAGGAGAACGGTGCCTTCACCGTGCTTGTTGACCACTATGTGAAG
GATGAAGAAGGCACAGGTGTCGTTCACCAGGCTCCTTACTTTGGCGCTGACGATCATCGAGTCT
GTATGGACTTCAACATCATTCAGAAAGACTCAGCCCCTGTTTGTCCTGTGGATGCTTCAGGCTG
CTTCACAGAGGAAGTGACACATTTTGTCGGGCAGTATGTGAAGGATGCTGACAAAAATATCATC
AGGATGTTGAAGGAGCAGGGCCGACTGCTCGTGGCAAGCACCTTCACTCACAGCTACCCTTTCT
GCTGGAGGTCGGACACTCCCCTCATTTACAAGTCCGTGCCCAGCTGGTTCGTGCGGGTGGAGCA
CATGGTGGACCAGCTACTGAAGAACAATGATCTGTGTTACTGGGTCCCAGAGTTTGTACGAGAA
AAACGGTTTGGAAATTGGCTGAAGGAGGCACGTGACTGGGCAATTTCCCGAAACAGATACTGGG
GCACCCCCATCCCACTGTGGGTCAGTGAAGACTTTGAGGAGGTAGTGTGCATCGGGTCAGTGGC
AGAACTTGAAGAATTGTCAGGAACAAAAATCTCAGATCTCCACAGAGAGAGCATCGACCACCTG
ACCATACCATCCCGCTGCGGGAAAGGACCGTTGCGGCGTGTCTCTGAGGTGTTTGACTGTTGGT
TCGAGAGTGGAAGTATGCCTTACGCCCAGGTTCATTACCCCTTTGAGAGCAAGCGAGAGTTCGA
GGATGCCTTTCCCGCAGACTTCATTGCTGAAGGCATCGATCAAACCAGAGGATGGTTTTACACC
CTGCTAGTGCTAGCCACAGCCCTCTTTGGACAACCACCTTTCAAGAACGTGATTGTGAACGGCC
TCATCTTGGCAAGTGATGGCCAAAAAATGAGCAAACGGAAAAAGAACTACCCAGATCCGGTTTC
CATCATCAATAAGTACGGTGCCGACGCCCTCAGGTTATATCTGATCAATTCCCCTGTGGTGAGA
GCAGAAAACCTGCGCTTCAAGGAGGAAGGCGTACGGGATGTCCTCAAAGACGTGCTGCTCCCAT
GGTACAACGCATACCGCTTCTTCATCCAGAACGTCTTTAGGCTGCACAAGGAAGAAGAAGTAGA
GTTTCTGTACAACGAGCACACGGTCCGAGAAAGCCCCAACATCACCGACCGGTGGATTCTGTCC
TTCATGCAGTCGCTCATTGCGTTCTTTGAGACGGAAATGGCAGCTTACAGGCTGTACACTGTGG
TGCCTCGCCTGGTCAAGTTCGTAGATATTCTGACCAACTGGTACGTCCGAATGAACAGGAGAAG
ATTAAAGGGGGAGAATGGCATGGAAGACTGTGTTATGGCTCTGGAGACTCTGTTCAGTGTCCTG
CTTTCTCTGTGCAGACTGATGGCCCCTTACACACCCTTTCTTACTGAACTGATGTACCAGAACC
TGAAGCTGCTGATTGACCCTGCATCTATCCGGGACAAGGACACCCTCAGCATCCACTACCTCAT
GCTGCCTCATGTTCGAGAGGAGCTGATTGACAAGAAAACTGAGAACGCCGTGTCTAGAATGCAG
TCCGTGATTGAGCTTGGGAGAGTGATTCGAGACCGGAAAACTATTCCAATAAAGTATCCCTTGA
AGGAAATTGTCGTCATCCACCAAGACCCAGAAGCTCTTGAGGATATCAAGTCCTTGGAGAAGTA
TATCATTGAGGAACTAAATGTTCGAAAAGTTACACTGTCTACTGATAAAAACAAGTATGGCATT
CGACTGAGGGCTGAGCCAGATCACATGGTCCTTGGGAAACGTCTGAAGGGAGCCTTTAAAGCAG
TGATGGTGGCCGTAAAGCAGCTGAGCAATGAGGAGCTGGAGCAGTTTCAGAAGAGTGGGAGCAT
CGTCGTGGAAGGCCATGAATTACACGAAGAAGATATTCGTCTCATGTACACCTTTGACCAGGCC
ACAGGAGGCACTGCACAGTTTGAAGCACACTCTGATGCTCAGGCTTTAGTTCTCTTAGATGTCA
CACCTGACCAGTCAATGGTGGACGAAGGCATGGCTCGGGAAGTCATCAATCGCATCCAGAAGCT
TCGCAAGAAGTGCAACCTGGTTCCGACGGATGAAATAACAGTTTACTATAATGCCAAATCTGAA
GGAAGATACTTGAGTAATGTCATCGAAAGCCACACTGACTTCATATATGCCACTATCAAAGCTC
CCTTGAAGCCCTATCCAGTTCCTACATCAGATAATATCCTTATTCAAGAGCAAACACAGTTAAA
GGGGTACGAGCTGGAAATCACGATCACCAGAGGATCCTGTGTGCCTGGGCCCGCTTGTGCTTAT
GTGAACCTTAACATTTGTGCAAATGGCACTGAGCAAGGTGGAGTGTTACTCCTGGAGAATCCGA
AGGGTGATAATCAGTTGAACCTTGAGAAGCTGAAGAGCGTCATTACCAGCATATTCGGTGTTAA
AAGCACAGGGCTGTCAGTCTTCAACGGTGGAACAGAATTACAGAACCAGACTGACTTGCTGAGC
CTCAGTGGAAGGACGCTGTGTGTGACTGCAGGAGCATCCCTGGCTCCAGCCAGCAGCCCCAGCA
CCCTTCTCTGTCAGTACATCAACCTGCAGCTCGTGAACGCAGAGCCACAAGAGTGTTTAACAGG
AACTGTGGGCACCCTCCTGCTTGAAAACCCACTTGGACAGAACGGGCTCACCCACCAAGGGCTT
GTGTACGAAGCAGCCAAGGTGTTTGGACTGCGCAGCCGGAGGCTAAAGCTGTTCCTGAATGAGA
CTCAGACACAAGAAATTACAGAAGATATCCCAATGAAGACTTTGAATATGAAGACTGTATATGT
TTCTGTCTTGCCAACGACTGCAGATGGCTAACAGTTAGTTATCAGTATGCCCTCAGTCAGCCTG
CCTTCCTGAATCTGCCCATCTCCTTACACACACACACACACACACACACACACACACACACACA
CACACACACACAGAGGCTCAGTGACGGTGTCTCCCTGGGACTCGTGTCTAATATGCTGCTTTGA
ACCTTCAATTCAAATGGGGATTGACTGACTTGAGACCTCACATAATGTTCACATTTAACCTTAA
ACACCTATGCAGTCCTGTGGGGGAGGGTCCTAACGTTACCTCAGCACCACAAAGCTTATTTCTA
TACTCGAGTTCTTCAGTACAGAAAGCGGAAGTGGTTTAAATGGCATAGTACATATACATACATA
TATATATAGCCTTGTAAAACTGATTTGTGACCTTGTGAAGAAATGGATATGTTATATATTTCTG
CTACCTGGATTTTCCTGGGTAATTTGATGAAATATTTTAAGTTTGATTAAATCAAAGTAAACAC
TCTCTCAGATACTG

hide sequence

RefSeq Acc Id:

XM_006253706 ⟹ XP_006253768

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	15,147,364 - 15,193,716 (-)	NCBI
mRatBN7.2	17	14,941,414 - 14,987,277 (-)	NCBI
Rnor_6.0	17	15,356,023 - 15,402,680 (-)	NCBI
Rnor_5.0	17	17,414,466 - 17,461,119 (-)	NCBI

Sequence:

show sequence

GGGGTTGAGCCTGGCACTGTCAGTATTGCATCACCTCCAGACGCGGAACGTGGTCGCAGTCTGC
AACCTGAGCTTGCTCACCTCAGGGTTCCCAGCAACAGAATGGTTCAACAAGTTCCGGAAAACAT
CAGCTTTCCTGCTGAAGAAGAAAAAATCTTACAGTTCTGGTCCAAATACAACTGTTTCCAGGAA
TGCCTAAAGCAGTCAAAGCTCAGGCCAAAGTTTACCTTCTATGATGGGCCTCCCTTCGCTACTG
GACTGCCTCACTACGGACACATACTTGCGGGGACAATTAAAGATATAGTTACAAGATACGCTCA
CCAGAGCGGGTTTCACGTCGACAGAAGATTCGGGTGGGATTGTCATGGCTTACCTGTGGAGTAC
GAGATTGACAAGACCCTGGGGATCAAAGGGCCAGAGGACGTGGCCAAGATGGGGATCGCAGAGT
ACAACAAGCAGTGCCGAGCTATTGTGATGAGGTACTCCGCCGAGTGGAAGTCTACTGTTACCAG
GCTTGGCCGATGGATCGACTTTGACAATGACTACAAAACCCTGTACCCACAATTCATGGAATCA
GTCTGGTGGGTCTTCAAGCAGCTGTATGACAAAGGCCTCGTGTACAGAGGCGTGAAAGTCATGC
CCTTCTCCACCGCGTGTGGAACTCCACTCTCCAACTTCGAGTCGAACCAGAATTACAAGGACGT
TCAGGACCCTTCAGTATTTGTAACGTTCCCTTTGGAGGAAGATGAAAACACATCCTTAGTTGCT
TGGACAACCACTCCGTGGACCCTACCCAGTAACCTTGCGCTATGTGTCAATCCAGAAATACAGT
ATGTGAAGATCAAAGACGTTTCCAGGGGGAAGTTGTTCATTTTGATGGAAGCCAGATTGTCGGC
CCTCTATAAACAAGAGAGCGACTATGAGATCCTTGAAAGGTTTCCTGGTGCCTCTCTCAAAGGC
AAGAAATACAAGCCGTTGTTTGACTACTTTATTAAGTGTAAGGAGAACGGTGCCTTCACCGTGC
TTGTTGACCACTATGTGAAGGATGAAGAAGGCACAGGTGTCGTTCACCAGGCTCCTTACTTTGG
CGCTGACGATCATCGAGTCTGTATGGACTTCAACATCATTCAGAAAGACTCAGCCCCTGTTTGT
CCTGTGGATGCTTCAGGCTGCTTCACAGAGGAAGTGACACATTTTGTCGGGCAGTATGTGAAGG
ATGCTGACAAAAATATCATCAGGATGTTGAAGGAGCAGGGCCGACTGCTCGTGGCAAGCACCTT
CACTCACAGCTACCCTTTCTGCTGGAGGTCGGACACTCCCCTCATTTACAAGTCCGTGCCCAGC
TGGTTCGTGCGGGTGGAGCACATGGTGGACCAGCTACTGAAGAACAATGATCTGTGTTACTGGG
TCCCAGAGTTTGTACGAGAAAAACGGTTTGGAAATTGGCTGAAGGAGGCACGTGACTGGGCAAT
TTCCCGAAACAGATACTGGGGCACCCCCATCCCACTGTGGGTCAGTGAAGACTTTGAGGAGGTA
GTGTGCATCGGGTCAGTGGCAGAACTTGAAGAATTGTCAGGAACAAAAATCTCAGATCTCCACA
GAGAGAGCATCGACCACCTGACCATACCATCCCGCTGCGGGAAAGGACCGTTGCGGCGTGTCTC
TGAGGTGTTTGACTGTTGGTTCGAGAGTGGAAGTATGCCTTACGCCCAGGTTCATTACCCCTTT
GAGAGCAAGCGAGAGTTCGAGGATGCCTTTCCCGCAGACTTCATTGCTGAAGGCATCGATCAAA
CCAGAGGATGGTTTTACACCCTGCTAGTGCTAGCCACAGCCCTCTTTGGACAACCACCTTTCAA
GAACGTGATTGTGAACGGCCTCATCTTGGCAAGTGATGGCCAAAAAATGAGCAAACGGAAAAAG
AACTACCCAGATCCGGTTTCCATCATCAATAAGTACGGTGCCGACGCCCTCAGGTTATATCTGA
TCAATTCCCCTGTGGTGAGAGCAGAAAACCTGCGCTTCAAGGAGGAAGGCGTACGGGATGTCCT
CAAAGACGTGCTGCTCCCATGGTACAACGCATACCGCTTCTTCATCCAGAACGTCTTTAGGCTG
CACAAGGAAGAAGAAGTAGAGTTTCTGTACAACGAGCACACGGTCCGAGAAAGCCCCAACATCA
CCGACCGGTGGATTCTGTCCTTCATGCAGTCGCTCATTGCGTTCTTTGAGACGGAAATGGCAGC
TTACAGGCTGTACACTGTGGTGCCTCGCCTGGTCAAGTTCGTAGATATTCTGACCAACTGGTAC
GTCCGAATGAACAGGAGAAGATTAAAGGGGGAGAATGGCATGGAAGACTGTGTTATGGCTCTGG
AGACTCTGTTCAGTGTCCTGCTTTCTCTGTGCAGACTGATGGCCCCTTACACACCCTTTCTTAC
TGAACTGATGTACCAGAACCTGAAGCTGCTGATTGACCCTGCATCTATCCGGGACAAGGACACC
CTCAGCATCCACTACCTCATGCTGCCTCATGTTCGAGAGGAGCTGATTGACAAGAAAACTGAGA
ACGCCGTGTCTAGAATGCAGTCCGTGATTGAGCTTGGGAGAGTGATTCGAGACCGGAAAACTAT
TCCAATAAAGTATCCCTTGAAGGAAATTGTCGTCATCCACCAAGACCCAGAAGCTCTTGAGGAT
ATCAAGTCCTTGGAGAAGTATATCATTGAGGAACTAAATGTTCGAAAAGTTACACTGTCTACTG
ATAAAAACAAGTATGGCATTCGACTGAGGGCTGAGCCAGATCACATGGTCCTTGGGAAACGTCT
GAAGGGAGCCTTTAAAGCAGTGATGGTGGCCGTAAAGCAGCTGAGCAATGAGGAGCTGGAGCAG
TTTCAGAAGAGTGGGAGCATCGTCGTGGAAGGCCATGAATTACACGAAGAAGATATTCGTCTCA
TGTACACCTTTGACCAGGCCACAGGAGGCACTGCACAGTTTGAAGCACACTCTGATGCTCAGGC
TTTAGTTCTCTTAGATGTCACACCTGACCAGTCAATGGTGGACGAAGGCATGGCTCGGGAAGTC
ATCAATCGCATCCAGAAGCTTCGCAAGAAGTGCAACCTGGTTCCGACGGATGAAATAACAGTTT
ACTATAATGCCAAATCTGAAGGAAGATACTTGAGTAATGTCATCGAAAGCCACACTGACTTCAT
ATATGCCACTATCAAAGCTCCCTTGAAGCCCTATCCAGTTCCTACATCAGATAATATCCTTATT
CAAGAGCAAACACAGTTAAAGGGGTACGAGCTGGAAATCACGATCACCAGAGGATCCTGTGTGC
CTGGGCCCGCTTGTGCTTATGTGAACCTTAACATTTGTGCAAATGGCACTGAGCAAGGTGGAGT
GTTACTCCTGGAGAATCCGAAGGGTGATAATCAGTTGAACCTTGAGAAGCTGAAGAGCGTCATT
ACCAGCATATTCGGTGTTAAAAGCACAGGGCTGTCAGTCTTCAACGGTGGAACAGAATTACAGA
ACCAGACTGACTTGCTGAGCCTCAGTGGAAGGACGCTGTGTGTGACTGCAGGAGCATCCCTGGC
TCCAGCCAGCAGCCCCAGCACCCTTCTCTGTCAGTACATCAACCTGCAGCTCGTGAACGCAGAG
CCACAAGAGTGTTTAACAGGAACTGTGGGCACCCTCCTGCTTGAAAACCCACTTGGACAGAACG
GGCTCACCCACCAAGGGCTTGTGTACGAAGCAGCCAAGGTGTTTGGACTGCGCAGCCGGAGGCT
AAAGCTGTTCCTGAATGAGACTCAGACACAAGAAATTACAGAAGATATCCCAATGAAGACTTTG
AATATGAAGACTGTATATGTTTCTGTCTTGCCAACGACTGCAGATGGCTAACAGTTAGTTATCA
GTATGCCCTCAGTCAGCCTGCCTTCCTGAATCTGCCCATCTCCTTACACACACACACACACACA
CACACACACACACACACACACACACACACACAGAGGCTCAGTGACGGTGTCTCCCTGGGACTCG
TGTCTAATATGCTGCTTTGAACCTTCAATTCAAATGGGGATTGACTGACTTGAGACCTCACATA
ATGTTCACATTTAACCTTAAACACCTATGCAGTCCTGTGGGGGAGGGTCCTAACGTTACCTCAG
CACCACAAAGCTTATTTCTATACTCGAGTTCTTCAGTACAGAAAGCGGAAGTGGTTTAAATGGC
ATAGTACATATACATACATATATATATAGCCTTGTAAAACTGATTTGTGACCTTGTGAAGAAAT
GGATATGTTATATATTTCTGCTACCTGGATTTTCCTGGGTAATTTGATGAAATATTTTAAGTTT
GATTAAATCAAAGTAAACACTCTCTCA

hide sequence

RefSeq Acc Id:

XM_008771533 ⟹ XP_008769755

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	15,147,364 - 15,193,684 (-)	NCBI
mRatBN7.2	17	14,941,414 - 14,987,254 (-)	NCBI
Rnor_6.0	17	15,356,023 - 15,402,679 (-)	NCBI

Sequence:

show sequence

GGGTTGAGCCTGGCACTGTCAGTATTGCATCACCTCCAGACGCGGAACGTGGTCGCAGTCTGCA
ACCTGAGCTTGCTCACCTCAGGGTTCCCAGGTGAGCCGCACCCTCCGCCCTTCCGGGCCTCAGA
GCGAGGCCTGCCGGTGTAACTATCTGTGGATAGCACCAGGCGGTGAAAAAGGAGCACGCTGATT
CCTTCCGTGAGTGAGCTGCGGGCACAGAGCTATTTCCACAGAGCCTTCGTGGAGGGAGAATAAC
TTTAGCTTGTGTCAAGTTGACGGAAAGCCATCCAGCACAAGAAGTGATTGAGCAACAGAATGGT
TCAACAAGTTCCGGAAAACATCAGCTTTCCTGCTGAAGAAGAAAAAATCTTACAGTTCTGGTCC
AAATACAACTGTTTCCAGGAATGCCTAAAGCAGTCAAAGCTCAGGCCAAAGTTTACCTTCTATG
ATGGGCCTCCCTTCGCTACTGGACTGCCTCACTACGGACACATACTTGCGGGGACAATTAAAGA
TATAGTTACAAGATACGCTCACCAGAGCGGGTTTCACGTCGACAGAAGATTCGGGTGGGATTGT
CATGGCTTACCTGTGGAGTACGAGATTGACAAGACCCTGGGGATCAAAGGGCCAGAGGACGTGG
CCAAGATGGGGATCGCAGAGTACAACAAGCAGTGCCGAGCTATTGTGATGAGGTACTCCGCCGA
GTGGAAGTCTACTGTTACCAGGCTTGGCCGATGGATCGACTTTGACAATGACTACAAAACCCTG
TACCCACAATTCATGGAATCAGTCTGGTGGGTCTTCAAGCAGCTGTATGACAAAGGCCTCGTGT
ACAGAGGCGTGAAAGTCATGCCCTTCTCCACCGCGTGTGGAACTCCACTCTCCAACTTCGAGTC
GAACCAGAATTACAAGGACGTTCAGGACCCTTCAGTATTTGTAACGTTCCCTTTGGAGGAAGAT
GAAAACACATCCTTAGTTGCTTGGACAACCACTCCGTGGACCCTACCCAGTAACCTTGCGCTAT
GTGTCAATCCAGAAATACAGTATGTGAAGATCAAAGACGTTTCCAGGGGGAAGTTGTTCATTTT
GATGGAAGCCAGATTGTCGGCCCTCTATAAACAAGAGAGCGACTATGAGATCCTTGAAAGGTTT
CCTGGTGCCTCTCTCAAAGGCAAGAAATACAAGCCGTTGTTTGACTACTTTATTAAGTGTAAGG
AGAACGGTGCCTTCACCGTGCTTGTTGACCACTATGTGAAGGATGAAGAAGGCACAGGTGTCGT
TCACCAGGCTCCTTACTTTGGCGCTGACGATCATCGAGTCTGTATGGACTTCAACATCATTCAG
AAAGACTCAGCCCCTGTTTGTCCTGTGGATGCTTCAGGCTGCTTCACAGAGGAAGTGACACATT
TTGTCGGGCAGTATGTGAAGGATGCTGACAAAAATATCATCAGGATGTTGAAGGAGCAGGGCCG
ACTGCTCGTGGCAAGCACCTTCACTCACAGCTACCCTTTCTGCTGGAGGTCGGACACTCCCCTC
ATTTACAAGTCCGTGCCCAGCTGGTTCGTGCGGGTGGAGCACATGGTGGACCAGCTACTGAAGA
ACAATGATCTGTGTTACTGGGTCCCAGAGTTTGTACGAGAAAAACGGTTTGGAAATTGGCTGAA
GGAGGCACGTGACTGGGCAATTTCCCGAAACAGATACTGGGGCACCCCCATCCCACTGTGGGTC
AGTGAAGACTTTGAGGAGGTAGTGTGCATCGGGTCAGTGGCAGAACTTGAAGAATTGTCAGGAA
CAAAAATCTCAGATCTCCACAGAGAGAGCATCGACCACCTGACCATACCATCCCGCTGCGGGAA
AGGACCGTTGCGGCGTGTCTCTGAGGTGTTTGACTGTTGGTTCGAGAGTGGAAGTATGCCTTAC
GCCCAGGTTCATTACCCCTTTGAGAGCAAGCGAGAGTTCGAGGATGCCTTTCCCGCAGACTTCA
TTGCTGAAGGCATCGATCAAACCAGAGGATGGTTTTACACCCTGCTAGTGCTAGCCACAGCCCT
CTTTGGACAACCACCTTTCAAGAACGTGATTGTGAACGGCCTCATCTTGGCAAGTGATGGCCAA
AAAATGAGCAAACGGAAAAAGAACTACCCAGATCCGGTTTCCATCATCAATAAGTACGGTGCCG
ACGCCCTCAGGTTATATCTGATCAATTCCCCTGTGGTGAGAGCAGAAAACCTGCGCTTCAAGGA
GGAAGGCGTACGGGATGTCCTCAAAGACGTGCTGCTCCCATGGTACAACGCATACCGCTTCTTC
ATCCAGAACGTCTTTAGGCTGCACAAGGAAGAAGAAGTAGAGTTTCTGTACAACGAGCACACGG
TCCGAGAAAGCCCCAACATCACCGACCGGTGGATTCTGTCCTTCATGCAGTCGCTCATTGCGTT
CTTTGAGACGGAAATGGCAGCTTACAGGCTGTACACTGTGGTGCCTCGCCTGGTCAAGTTCGTA
GATATTCTGACCAACTGGTACGTCCGAATGAACAGGAGAAGATTAAAGGGGGAGAATGGCATGG
AAGACTGTGTTATGGCTCTGGAGACTCTGTTCAGTGTCCTGCTTTCTCTGTGCAGACTGATGGC
CCCTTACACACCCTTTCTTACTGAACTGATGTACCAGAACCTGAAGCTGCTGATTGACCCTGCA
TCTATCCGGGACAAGGACACCCTCAGCATCCACTACCTCATGCTGCCTCATGTTCGAGAGGAGC
TGATTGACAAGAAAACTGAGAACGCCGTGTCTAGAATGCAGTCCGTGATTGAGCTTGGGAGAGT
GATTCGAGACCGGAAAACTATTCCAATAAAGTATCCCTTGAAGGAAATTGTCGTCATCCACCAA
GACCCAGAAGCTCTTGAGGATATCAAGTCCTTGGAGAAGTATATCATTGAGGAACTAAATGTTC
GAAAAGTTACACTGTCTACTGATAAAAACAAGTATGGCATTCGACTGAGGGCTGAGCCAGATCA
CATGGTCCTTGGGAAACGTCTGAAGGGAGCCTTTAAAGCAGTGATGGTGGCCGTAAAGCAGCTG
AGCAATGAGGAGCTGGAGCAGTTTCAGAAGAGTGGGAGCATCGTCGTGGAAGGCCATGAATTAC
ACGAAGAAGATATTCGTCTCATGTACACCTTTGACCAGGCCACAGGAGGCACTGCACAGTTTGA
AGCACACTCTGATGCTCAGGCTTTAGTTCTCTTAGATGTCACACCTGACCAGTCAATGGTGGAC
GAAGGCATGGCTCGGGAAGTCATCAATCGCATCCAGAAGCTTCGCAAGAAGTGCAACCTGGTTC
CGACGGATGAAATAACAGTTTACTATAATGCCAAATCTGAAGGAAGATACTTGAGTAATGTCAT
CGAAAGCCACACTGACTTCATATATGCCACTATCAAAGCTCCCTTGAAGCCCTATCCAGTTCCT
ACATCAGATAATATCCTTATTCAAGAGCAAACACAGTTAAAGGGGTACGAGCTGGAAATCACGA
TCACCAGAGGATCCTGTGTGCCTGGGCCCGCTTGTGCTTATGTGAACCTTAACATTTGTGCAAA
TGGCACTGAGCAAGGTGGAGTGTTACTCCTGGAGAATCCGAAGGGTGATAATCAGTTGAACCTT
GAGAAGCTGAAGAGCGTCATTACCAGCATATTCGGTGTTAAAAGCACAGGGCTGTCAGTCTTCA
ACGGTGGAACAGAATTACAGAACCAGACTGACTTGCTGAGCCTCAGTGGAAGGACGCTGTGTGT
GACTGCAGGAGCATCCCTGGCTCCAGCCAGCAGCCCCAGCACCCTTCTCTGTCAGTACATCAAC
CTGCAGCTCGTGAACGCAGAGCCACAAGAGTGTTTAACAGGAACTGTGGGCACCCTCCTGCTTG
AAAACCCACTTGGACAGAACGGGCTCACCCACCAAGGGCTTGTGTACGAAGCAGCCAAGGTGTT
TGGACTGCGCAGCCGGAGGCTAAAGCTGTTCCTGAATGAGACTCAGACACAAGAAATTACAGAA
GATATCCCAATGAAGACTTTGAATATGAAGACTGTATATGTTTCTGTCTTGCCAACGACTGCAG
ATGGCTAACAGTTAGTTATCAGTATGCCCTCAGTCAGCCTGCCTTCCTGAATCTGCCCATCTCC
TTACACACACACACACACACACACACACACACACACACACACACACACACACAGAGGCTCAGTG
ACGGTGTCTCCCTGGGACTCGTGTCTAATATGCTGCTTTGAACCTTCAATTCAAATGGGGATTG
ACTGACTTGAGACCTCACATAATGTTCACATTTAACCTTAAACACCTATGCAGTCCTGTGGGGG
AGGGTCCTAACGTTACCTCAGCACCACAAAGCTTATTTCTATACTCGAGTTCTTCAGTACAGAA
AGCGGAAGTGGTTTAAATGGCATAGTACATATACATACATATATATATAGCCTTGTAAAACTGA
TTTGTGACCTTGTGAAGAAATGGATATGTTATATATTTCTGCTACCTGGATTTTCCTGGGTAAT
TTGATGAAATATTTTAAGTTTGATTAAATCAAAGTAAACACTCTCTCA

hide sequence

RefSeq Acc Id:

XM_063276354 ⟹ XP_063132424

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	15,147,364 - 15,193,675 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001094042	(Get FASTA)	NCBI Sequence Viewer
	XP_006253768	(Get FASTA)	NCBI Sequence Viewer
	XP_008769755	(Get FASTA)	NCBI Sequence Viewer
	XP_063132424	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH91369	(Get FASTA)	NCBI Sequence Viewer
	EDL98104	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000019862
	ENSRNOP00000019862.6

RefSeq Acc Id:

NP_001094042 ⟸ NM_001100572

- UniProtKB:

A0A1W2Q6K1 (UniProtKB/TrEMBL), A6J6V4 (UniProtKB/TrEMBL), F1LS86 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MVQQVPENISFPAEEEKILQFWSKYNCFQECLKQSKLRPKFTFYDGPPFATGLPHYGHILAGTI
KDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIKGPEDVAKMGIAEYNKQCRAIVMRYS
AEWKSTVTRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACGTPLSNF
ESNQNYKDVQDPSVFVTFPLEEDENTSLVAWTTTPWTLPSNLALCVNPEIQYVKIKDVSRGKLF
ILMEARLSALYKQESDYEILERFPGASLKGKKYKPLFDYFIKCKENGAFTVLVDHYVKDEEGTG
VVHQAPYFGADDHRVCMDFNIIQKDSAPVCPVDASGCFTEEVTHFVGQYVKDADKNIIRMLKEQ
GRLLVASTFTHSYPFCWRSDTPLIYKSVPSWFVRVEHMVDQLLKNNDLCYWVPEFVREKRFGNW
LKEARDWAISRNRYWGTPIPLWVSEDFEEVVCIGSVAELEELSGTKISDLHRESIDHLTIPSRC
GKGPLRRVSEVFDCWFESGSMPYAQVHYPFESKREFEDAFPADFIAEGIDQTRGWFYTLLVLAT
ALFGQPPFKNVIVNGLILASDGQKMSKRKKNYPDPVSIINKYGADALRLYLINSPVVRAENLRF
KEEGVRDVLKDVLLPWYNAYRFFIQNVFRLHKEEEVEFLYNEHTVRESPNITDRWILSFMQSLI
AFFETEMAAYRLYTVVPRLVKFVDILTNWYVRMNRRRLKGENGMEDCVMALETLFSVLLSLCRL
MAPYTPFLTELMYQNLKLLIDPASIRDKDTLSIHYLMLPHVREELIDKKTENAVSRMQSVIELG
RVIRDRKTIPIKYPLKEIVVIHQDPEALEDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEP
DHMVLGKRLKGAFKAVMVAVKQLSNEELEQFQKSGSIVVEGHELHEEDIRLMYTFDQATGGTAQ
FEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYNAKSEGRYLSN
VIESHTDFIYATIKAPLKPYPVPTSDNILIQEQTQLKGYELEITITRGSCVPGPACAYVNLNIC
ANGTEQGGVLLLENPKGDNQLNLEKLKSVITSIFGVKSTGLSVFNGGTELQNQTDLLSLSGRTL
CVTAGASLAPASSPSTLLCQYINLQLVNAEPQECLTGTVGTLLLENPLGQNGLTHQGLVYEAAK
VFGLRSRRLKLFLNETQTQEITEDIPMKTLNMKTVYVSVLPTTADG

hide sequence

RefSeq Acc Id:	XP_006253768 ⟸ XM_006253706
- Peptide Label:	isoform X1
- UniProtKB:	A0A1W2Q6K1 (UniProtKB/TrEMBL), A6J6V4 (UniProtKB/TrEMBL), F1LS86 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVQQVPENISFPAEEEKILQFWSKYNCFQECLKQSKLRPKFTFYDGPPFATGLPHYGHILAGTI KDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIKGPEDVAKMGIAEYNKQCRAIVMRYS AEWKSTVTRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACGTPLSNF ESNQNYKDVQDPSVFVTFPLEEDENTSLVAWTTTPWTLPSNLALCVNPEIQYVKIKDVSRGKLF ILMEARLSALYKQESDYEILERFPGASLKGKKYKPLFDYFIKCKENGAFTVLVDHYVKDEEGTG VVHQAPYFGADDHRVCMDFNIIQKDSAPVCPVDASGCFTEEVTHFVGQYVKDADKNIIRMLKEQ GRLLVASTFTHSYPFCWRSDTPLIYKSVPSWFVRVEHMVDQLLKNNDLCYWVPEFVREKRFGNW LKEARDWAISRNRYWGTPIPLWVSEDFEEVVCIGSVAELEELSGTKISDLHRESIDHLTIPSRC GKGPLRRVSEVFDCWFESGSMPYAQVHYPFESKREFEDAFPADFIAEGIDQTRGWFYTLLVLAT ALFGQPPFKNVIVNGLILASDGQKMSKRKKNYPDPVSIINKYGADALRLYLINSPVVRAENLRF KEEGVRDVLKDVLLPWYNAYRFFIQNVFRLHKEEEVEFLYNEHTVRESPNITDRWILSFMQSLI AFFETEMAAYRLYTVVPRLVKFVDILTNWYVRMNRRRLKGENGMEDCVMALETLFSVLLSLCRL MAPYTPFLTELMYQNLKLLIDPASIRDKDTLSIHYLMLPHVREELIDKKTENAVSRMQSVIELG RVIRDRKTIPIKYPLKEIVVIHQDPEALEDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEP DHMVLGKRLKGAFKAVMVAVKQLSNEELEQFQKSGSIVVEGHELHEEDIRLMYTFDQATGGTAQ FEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYNAKSEGRYLSN VIESHTDFIYATIKAPLKPYPVPTSDNILIQEQTQLKGYELEITITRGSCVPGPACAYVNLNIC ANGTEQGGVLLLENPKGDNQLNLEKLKSVITSIFGVKSTGLSVFNGGTELQNQTDLLSLSGRTL CVTAGASLAPASSPSTLLCQYINLQLVNAEPQECLTGTVGTLLLENPLGQNGLTHQGLVYEAAK VFGLRSRRLKLFLNETQTQEITEDIPMKTLNMKTVYVSVLPTTADG hide sequence

RefSeq Acc Id:	XP_008769755 ⟸ XM_008771533
- Peptide Label:	isoform X1
- UniProtKB:	A0A1W2Q6K1 (UniProtKB/TrEMBL), A6J6V4 (UniProtKB/TrEMBL), F1LS86 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVQQVPENISFPAEEEKILQFWSKYNCFQECLKQSKLRPKFTFYDGPPFATGLPHYGHILAGTI KDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIKGPEDVAKMGIAEYNKQCRAIVMRYS AEWKSTVTRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACGTPLSNF ESNQNYKDVQDPSVFVTFPLEEDENTSLVAWTTTPWTLPSNLALCVNPEIQYVKIKDVSRGKLF ILMEARLSALYKQESDYEILERFPGASLKGKKYKPLFDYFIKCKENGAFTVLVDHYVKDEEGTG VVHQAPYFGADDHRVCMDFNIIQKDSAPVCPVDASGCFTEEVTHFVGQYVKDADKNIIRMLKEQ GRLLVASTFTHSYPFCWRSDTPLIYKSVPSWFVRVEHMVDQLLKNNDLCYWVPEFVREKRFGNW LKEARDWAISRNRYWGTPIPLWVSEDFEEVVCIGSVAELEELSGTKISDLHRESIDHLTIPSRC GKGPLRRVSEVFDCWFESGSMPYAQVHYPFESKREFEDAFPADFIAEGIDQTRGWFYTLLVLAT ALFGQPPFKNVIVNGLILASDGQKMSKRKKNYPDPVSIINKYGADALRLYLINSPVVRAENLRF KEEGVRDVLKDVLLPWYNAYRFFIQNVFRLHKEEEVEFLYNEHTVRESPNITDRWILSFMQSLI AFFETEMAAYRLYTVVPRLVKFVDILTNWYVRMNRRRLKGENGMEDCVMALETLFSVLLSLCRL MAPYTPFLTELMYQNLKLLIDPASIRDKDTLSIHYLMLPHVREELIDKKTENAVSRMQSVIELG RVIRDRKTIPIKYPLKEIVVIHQDPEALEDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEP DHMVLGKRLKGAFKAVMVAVKQLSNEELEQFQKSGSIVVEGHELHEEDIRLMYTFDQATGGTAQ FEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYNAKSEGRYLSN VIESHTDFIYATIKAPLKPYPVPTSDNILIQEQTQLKGYELEITITRGSCVPGPACAYVNLNIC ANGTEQGGVLLLENPKGDNQLNLEKLKSVITSIFGVKSTGLSVFNGGTELQNQTDLLSLSGRTL CVTAGASLAPASSPSTLLCQYINLQLVNAEPQECLTGTVGTLLLENPLGQNGLTHQGLVYEAAK VFGLRSRRLKLFLNETQTQEITEDIPMKTLNMKTVYVSVLPTTADG hide sequence

Ensembl Acc Id:

ENSRNOP00000076307 ⟸ ENSRNOT00000093637

Ensembl Acc Id:

ENSRNOP00000019862 ⟸ ENSRNOT00000019862

Ensembl Acc Id:

ENSRNOP00000069534 ⟸ ENSRNOT00000086344

Ensembl Acc Id:

ENSRNOP00000071046 ⟸ ENSRNOT00000078166

Ensembl Acc Id:

ENSRNOP00000085677 ⟸ ENSRNOT00000101044

RefSeq Acc Id:	XP_063132424 ⟸ XM_063276354
- Peptide Label:	isoform X1
- UniProtKB:	A0A1W2Q6K1 (UniProtKB/TrEMBL), A6J6V4 (UniProtKB/TrEMBL), F1LS86 (UniProtKB/TrEMBL)

Protein Domains

Aminoacyl-tRNA synthetase class Ia Isoleucine--tRNA ligase cytoplasmic ubiquitin-like Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2JZH2-F1-model_v2	AlphaFold	A0A0G2JZH2	1-501	view protein structure
AF-F1LS86-F1-model_v2	AlphaFold	F1LS86	1-1262	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700350

Promoter ID:

EPDNEW_R10872

Type:

initiation region

Name:

Iars_1

Description:

isoleucyl-tRNA synthetase

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	17	15,402,648 - 15,402,708	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621022	AgrOrtholog
BioCyc Gene	G2FUF-10009	BioCyc
BioCyc Pathway	TRNA-CHARGING-PWY [tRNA charging]	BioCyc
BioCyc Pathway Image	TRNA-CHARGING-PWY	BioCyc
Ensembl Genes	ENSRNOG00000014616	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOG00000052977	Ensembl
Ensembl Transcript	ENSRNOT00000019862	ENTREZGENE
	ENSRNOT00000019862.8	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.620	UniProtKB/TrEMBL
	Isoleucyl-tRNA Synthetase, Domain 1	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7319346	IMAGE-MGC_LOAD
InterPro	aa-tRNA-synth_I_CS	UniProtKB/TrEMBL
	aa-tRNA-synth_Ia	UniProtKB/TrEMBL
	Anticodon_Ile_ABEc	UniProtKB/TrEMBL
	Ile-tRNA-ligase	UniProtKB/TrEMBL
	Ile-tRNA-ligase_type2	UniProtKB/TrEMBL
	Rossmann-like_a/b/a_fold	UniProtKB/TrEMBL
	tRNAsynth_1a_anticodon-bd	UniProtKB/TrEMBL
	Ubiquitin_IARS1	UniProtKB/TrEMBL
	V/L/I-tRNA-synth_anticodon-bd	UniProtKB/TrEMBL
	Val/Leu/Ile-tRNA-synth_edit	UniProtKB/TrEMBL
KEGG Report	rno:306804	UniProtKB/TrEMBL
MGC_CLONE	MGC:109429	IMAGE-MGC_LOAD
NCBI Gene	Iars1	ENTREZGENE
PANTHER	ISOLEUCINE--TRNA LIGASE, CYTOPLASMIC	UniProtKB/TrEMBL
	PTHR42780	UniProtKB/TrEMBL
Pfam	Anticodon_1	UniProtKB/TrEMBL
	DUF5915	UniProtKB/TrEMBL
	tRNA-synt_1	UniProtKB/TrEMBL
	Ubiquitin_IARS1	UniProtKB/TrEMBL
PhenoGen	Iars1	PhenoGen
PRINTS	TRNASYNTHILE	UniProtKB/TrEMBL
PROSITE	AA_TRNA_LIGASE_I	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000014616	RatGTEx
	ENSRNOG00000052977	RatGTEx
Superfamily-SCOP	Nucleotidylyl transferase	UniProtKB/TrEMBL
	tRNAsyn_1a_bind	UniProtKB/TrEMBL
	ValRS_IleRS_edit	UniProtKB/TrEMBL
UniProt	A0A1W2Q6K1	ENTREZGENE
	A6J6V4	ENTREZGENE, UniProtKB/TrEMBL
	F1LS86	ENTREZGENE, UniProtKB/TrEMBL
	Q5BJR3_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Iars1	isoleucyl-tRNA synthetase 1	LOC103690033	isoleucine--tRNA ligase, cytoplasmic-like	Data merged from RGD:9226700	737654	PROVISIONAL
2019-08-08	Iars1	isoleucyl-tRNA synthetase 1	Iars	isoleucyl-tRNA synthetase	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2014-08-25	LOC103690033	isoleucine--tRNA ligase, cytoplasmic-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-11-06	Iars	isoleucyl-tRNA synthetase	Iars	isoleucine-tRNA synthetase	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-23	Iars	isoleucine-tRNA synthetase	Iarsl	isoleucine-tRNA synthetase-like	Symbol and Name updated to reflect Human and Mouse nomenclature	1299863	APPROVED
2008-09-23	Iarsl	isoleucine-tRNA synthetase-like	Iars	isoleucine-tRNA synthetase	Data merged from RGD:1308206	737654	APPROVED
2008-05-05	Iars	isoleucine-tRNA synthetase	Iars_predicted	isoleucine-tRNA synthetase (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-05-05	Iarsl	isoleucine-tRNA synthetase-like	Iars	isoleucine-tRNA synthetase	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	Iars	isoleucine-tRNA synthetase			Symbol and Name status set to approved	1299863	APPROVED
2005-01-12	Iars_predicted	isoleucine-tRNA synthetase (predicted)			Symbol and Name status set to approved	70820	APPROVED
2002-08-07	Iars	isoleucine-tRNA synthetase			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed in the vascular smooth muscle cells	631940
gene_process	maybe involved in determining distinctive epithelioid phenotype of smooth muscle cells	631940
gene_regulation	over-expressed after injury	631940

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

External Pathway Database Links

BioCyc Pathways

External Pathway Database Links

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

External Pathway Database Links

BioCyc Pathways

External Pathway Database Links