Calb2 (calbindin 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Calb2 (calbindin 2) Rattus norvegicus
Analyze
Symbol: Calb2
Name: calbindin 2
RGD ID: 620981
Description: Enables calcium ion binding activity. Predicted to be involved in regulation of presynaptic cytosolic calcium ion concentration. Located in cuticular plate and stereocilium. Is active in synapse. Orthologous to human CALB2 (calbindin 2); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH (R)-lipoic acid; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: calretinin; CR; MGC105356
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Eau8
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81955,023,849 - 55,050,858 (-)NCBIGRCr8
mRatBN7.21938,114,435 - 38,141,438 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1938,114,424 - 38,141,438 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1944,920,886 - 44,947,919 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01945,574,230 - 45,601,269 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01947,883,801 - 47,910,840 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01941,482,743 - 41,509,617 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1941,482,728 - 41,509,658 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01952,310,641 - 52,337,700 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41940,023,072 - 40,051,150 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11940,027,952 - 40,056,031 (-)NCBI
Celera1937,512,226 - 37,538,062 (-)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Calb2RatEndometrial Neoplasms  ISOCALB2 (Homo sapiens)2315881protein:decreased expression:endometriumRGD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Calb2Ratautosomal dominant dyskeratosis congenita 6  ISOCALB2 (Homo sapiens)8554872ClinVar Annotator: match by term: Dyskeratosis congenita and autosomal dominant 6ClinVarPMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Calb2Ratamyotrophic lateral sclerosis type 1  ISOCALB2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:11796754
Calb2Ratmalignant mesothelioma  ISOCALB2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:22784439
Calb2RatPeritoneal Neoplasms  ISOCALB2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:22784439
Calb2Ratuveitis  ISOCALB2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:19578012

1 to 20 of 121 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Calb2Rat(R)-lipoic acid multiple interactionsEXP 6480464Thioctic Acid affects the reaction [Propylthiouracil results in increased expression of CALB2 mRNA]CTDPMID:31068541
Calb2Rat1,2-dimethylhydrazine increases expressionISOCalb2 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of CALB2 mRNACTDPMID:22206623
Calb2Rat17beta-estradiol affects expressionISOCALB2 (Homo sapiens)6480464Estradiol affects the expression of CALB2 mRNACTDPMID:14699072
Calb2Rat17beta-estradiol increases expressionISOCALB2 (Homo sapiens)6480464Estradiol results in increased expression of CALB2 mRNACTDPMID:17121429 and PMID:17962382
Calb2Rat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISOCalb2 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Calb2Rat2,2',5,5'-tetrachlorobiphenyl multiple interactionsISOCalb2 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Calb2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOCalb2 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of CALB2 mRNACTDPMID:21570461
Calb2Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of CALB2 mRNACTDPMID:32109520
Calb2Rat2,3,7,8-Tetrachlorodibenzofuran decreases expressionEXP 64804642 more ...CTDPMID:32109520
Calb2Rat2-hydroxypropanoic acid decreases expressionISOCALB2 (Homo sapiens)6480464Lactic Acid results in decreased expression of CALB2 mRNACTDPMID:30851411
Calb2Rat2-palmitoylglycerol increases expressionISOCALB2 (Homo sapiens)64804642-palmitoylglycerol results in increased expression of CALB2 mRNACTDPMID:37199045
Calb2Rat3-chloropropane-1,2-diol increases expressionEXP 6480464alpha-Chlorohydrin results in increased expression of CALB2 mRNACTDPMID:28522335
Calb2Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISOCALB2 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of CALB2 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of CALB2 mRNACTDPMID:28628672
Calb2Rat3-methylcholanthrene multiple interactionsISOCALB2 (Homo sapiens)6480464Methylcholanthrene promotes the reaction [AHR protein binds to CALB2 promoter]CTDPMID:20348232
Calb2Rat5-fluorouracil increases response to substanceISOCALB2 (Homo sapiens)6480464CALB2 protein results in increased susceptibility to FluorouracilCTDPMID:16510598
Calb2Rat5-fluorouracil increases expressionISOCALB2 (Homo sapiens)6480464Fluorouracil results in increased expression of CALB2 mRNACTDPMID:16510598
Calb2Rat6-propyl-2-thiouracil affects expressionEXP 6480464Propylthiouracil affects the expression of CALB2 mRNACTDPMID:24780913
Calb2Rat6-propyl-2-thiouracil multiple interactionsEXP 6480464Thioctic Acid affects the reaction [Propylthiouracil results in increased expression of CALB2 mRNA]CTDPMID:31068541
Calb2Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of CALB2 mRNACTDPMID:31068541
Calb2Rataflatoxin B1 increases expressionISOCALB2 (Homo sapiens)6480464Aflatoxin B1 results in increased expression of CALB2 mRNACTDPMID:32234424

1 to 20 of 121 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Calb2Ratbiological_process  ND 159840701/2009: no relevant rat dataRGD 
Calb2Ratintracellular calcium ion homeostasis involved_inISSUniProtKB:Q083311600115GO_REF:0000024UniProtGO_REF:0000024
Calb2Ratregulation of presynaptic cytosolic calcium ion concentration involved_inIEAGO:00995341600115GO_REF:0000108GOCGO_REF:0000108
Calb2Ratregulation of synaptic plasticity involved_inISSUniProtKB:Q083311600115GO_REF:0000024UniProtGO_REF:0000024
Calb2Ratsynaptic signaling involved_inISSUniProtKB:Q083311600115GO_REF:0000024UniProtGO_REF:0000024

Cellular Component
1 to 20 of 24 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Calb2Ratcuticular plate  IDA 7175527 RGD 
Calb2Ratcytosol located_inIEAUniProtKB:A0A140VK08 and ensembl:ENSP000003075081600115GO_REF:0000107EnsemblGO_REF:0000107
Calb2Ratcytosol is_active_inIBAMGI:88248 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Calb2Ratcytosol located_inISOCALB2 (Homo sapiens)1624291 RGDGO_REF:0000052
Calb2Ratcytosol located_inIEAUniProtKB:P22676 and ensembl:ENSP000003075081600115GO_REF:0000107EnsemblGO_REF:0000107
Calb2Ratdendriole located_inISOCalb2 (Mus musculus)1624291 PMID:33488348RGDPMID:33488348
Calb2Ratdendriole located_inISSUniProtKB:Q083311600115GO_REF:0000024UniProtGO_REF:0000024
Calb2Ratdendrite located_inIEAUniProtKB-SubCell:SL-02831600115GO_REF:0000044UniProtGO_REF:0000044
Calb2Ratdendrite is_active_inIBAMGI:88248 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Calb2Ratgap junction located_inISOCalb2 (Mus musculus)1624291 PMID:12868005RGDPMID:12868005
Calb2Ratneuronal cell body  ISOCalb2 (Chinchilla lanigera)1624291 RGD (All species) and (All species)
Calb2Ratnucleus is_active_inIBAMGI:88248 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Calb2Ratparallel fiber to Purkinje cell synapse is_active_inISOCalb2 (Mus musculus)1624291 PMID:23273895RGDPMID:23273895
Calb2Ratparallel fiber to Purkinje cell synapse is_active_inISSUniProtKB:Q083311600115GO_REF:0000024UniProtGO_REF:0000024
Calb2Ratpresynapse located_inIEAGO:00995091600115GO_REF:0000108GOCGO_REF:0000108
Calb2Ratstereocilium  IDA 7175527 RGD 
Calb2Ratsynapse located_inIEAUniProtKB-SubCell:SL-02581600115GO_REF:0000044UniProtGO_REF:0000044
Calb2Ratsynapse is_active_inIBAFB:FBgn0004580 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Calb2Ratsynapse is_active_inIEP 13702199PMID:7790883SynGO 
Calb2Ratsynapse is_active_inIDA 13702199PMID:7790883SynGO 
1 to 20 of 24 rows

Molecular Function

  

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Calb2Ratcalcium/calcium-mediated signaling pathway   ISOCALB2 (Homo sapiens)7204685 RGD 

1 to 15 of 15 rows
#
Reference Title
Reference Citation
1. De novo expression of calretinin in trimethyltin-induced degeneration of developing rat hippocampus. Businaro R, etal., Brain Res Mol Brain Res 2002 Jan 31;98(1-2):141-4.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. The concentrations of calcium buffering proteins in mammalian cochlear hair cells. Hackney CM, etal., J Neurosci. 2005 Aug 24;25(34):7867-75.
4. Calretinin and CD34 immunoreactivity of the endometrial stroma in normal endometrium and change of the immunoreactivity in dysfunctional uterine bleeding with evidence of 'disordered endometrial stroma'. Mai KT, etal., Pathology. 2008 Aug;40(5):493-9.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. Structural and biochemical characterization of neuronal calretinin domain I-II (residues 1-100). Comparison to homologous calbindin D28k domain I-II (residues 1-93). Palczewska M, etal., Eur J Biochem. 2001 Dec;268(23):6229-37.
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. Cytosolic Ca2+ buffers. Schwaller B, Cold Spring Harb Perspect Biol. 2010 Nov;2(11):a004051. doi: 10.1101/cshperspect.a004051. Epub 2010 Oct 13.
12. Nucleotide sequence of rat calretinin cDNA. Strauss KI and Jacobowitz DM, Neurochem Int 1993 Jun;22(6):541-6.
13. Immunocytochemical detection of calretinin in the claustrum and endopiriform nucleus of the chinchilla. Szalak R, etal., Pol J Vet Sci. 2015;18(4):857-63. doi: 10.1515/pjvs-2015-0111.
14. Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins. Wilhelm BG, etal., Science. 2014 May 30;344(6187):1023-8. doi: 10.1126/science.1252884.
15. Distribution of calretinin, calbindin D28k, and parvalbumin in subcellular fractions of rat cerebellum: effects of calcium. Winsky L and Kuznicki J, J Neurochem. 1995 Jul;65(1):381-8.
1 to 15 of 15 rows
PMID:1988053   PMID:7918640   PMID:12477932   PMID:12577320   PMID:12868005   PMID:14730585   PMID:15093134   PMID:15355314   PMID:15489334   PMID:17177263   PMID:17965879   PMID:18720478  
PMID:18769561   PMID:21080000   PMID:21394464   PMID:21835217   PMID:22037839   PMID:22221733   PMID:23273895   PMID:24134921   PMID:25730969   PMID:25813826   PMID:33040447  



Calb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81955,023,849 - 55,050,858 (-)NCBIGRCr8
mRatBN7.21938,114,435 - 38,141,438 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1938,114,424 - 38,141,438 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1944,920,886 - 44,947,919 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01945,574,230 - 45,601,269 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01947,883,801 - 47,910,840 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01941,482,743 - 41,509,617 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1941,482,728 - 41,509,658 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01952,310,641 - 52,337,700 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41940,023,072 - 40,051,150 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11940,027,952 - 40,056,031 (-)NCBI
Celera1937,512,226 - 37,538,062 (-)NCBICelera
Cytogenetic Map19q12NCBI
CALB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381671,358,723 - 71,390,433 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1671,358,713 - 71,390,436 (+)EnsemblGRCh38hg38GRCh38
GRCh371671,392,626 - 71,424,336 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361669,950,127 - 69,981,842 (+)NCBINCBI36Build 36hg18NCBI36
Build 341669,950,126 - 69,981,836NCBI
Celera1655,708,128 - 55,740,202 (+)NCBICelera
Cytogenetic Map16q22.2NCBI
HuRef1657,186,719 - 57,192,385 (+)NCBIHuRef
HuRef1657,160,840 - 57,186,546 (+)NCBIHuRef
CHM1_11672,805,453 - 72,837,193 (+)NCBICHM1_1
T2T-CHM13v2.01677,174,637 - 77,207,658 (+)NCBIT2T-CHM13v2.0
Calb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398110,869,158 - 110,894,844 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8110,864,134 - 110,894,842 (-)EnsemblGRCm39 Ensembl
GRCm388110,142,526 - 110,168,212 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8110,137,502 - 110,168,210 (-)EnsemblGRCm38mm10GRCm38
MGSCv378112,666,438 - 112,692,106 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368113,031,667 - 113,057,335 (-)NCBIMGSCv36mm8
Celera8114,365,078 - 114,391,219 (-)NCBICelera
Cytogenetic Map8D3NCBI
cM Map857.44NCBI
Calb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554844,075,067 - 4,103,559 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554844,075,103 - 4,103,509 (+)NCBIChiLan1.0ChiLan1.0
CALB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21882,768,831 - 82,801,912 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11688,702,425 - 88,982,493 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01653,620,317 - 53,653,372 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11671,195,770 - 71,227,937 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1671,195,770 - 71,227,937 (+)Ensemblpanpan1.1panPan2
CALB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1577,178,158 - 77,205,663 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl577,177,951 - 77,205,671 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha577,139,985 - 77,167,208 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0577,616,925 - 77,644,159 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl577,616,951 - 77,644,096 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1577,437,354 - 77,464,585 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0577,260,506 - 77,287,715 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0577,759,356 - 77,786,581 (+)NCBIUU_Cfam_GSD_1.0
Calb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934937,217,095 - 37,244,688 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647522,341,822 - 22,372,609 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647522,344,416 - 22,372,015 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CALB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl614,391,857 - 14,420,663 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1614,392,220 - 14,420,663 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2613,904,114 - 13,933,267 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CALB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1554,503,635 - 54,538,304 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl554,504,082 - 54,538,441 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604717,312,991 - 17,345,343 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Calb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474613,548,540 - 13,578,501 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474613,549,339 - 13,577,929 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Calb2
103 total Variants

Predicted Target Of
Summary Value
Count of predictions:88
Count of miRNA genes:73
Interacting mature miRNAs:83
Transcripts:ENSRNOT00000022943
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 18 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)192932249057337602Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)193383821455283146Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19745724942983518Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191082797043544039Rat

1 to 10 of 18 rows
D19Rat71  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81955,039,510 - 55,039,721 (+)Marker Load Pipeline
mRatBN7.21938,130,095 - 38,130,307 (-)MAPPERmRatBN7.2
Rnor_6.01941,493,877 - 41,494,088NCBIRnor6.0
Rnor_5.01952,321,960 - 52,322,171UniSTSRnor5.0
RH 3.4 Map19437.4RGD
RH 3.4 Map19437.4UniSTS
RH 2.0 Map19481.8RGD
SHRSP x BN Map1927.8698RGD
Cytogenetic Map19q12UniSTS
X73985  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21938,114,703 - 38,114,871 (-)MAPPERmRatBN7.2
Rnor_6.01941,509,181 - 41,509,348NCBIRnor6.0
Rnor_5.01952,337,264 - 52,337,431UniSTSRnor5.0
RGSC_v3.41940,023,341 - 40,023,508UniSTSRGSC3.4
Celera1937,512,495 - 37,512,662UniSTS
Cytogenetic Map19q12UniSTS
RH138609  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21938,114,524 - 38,114,704 (-)MAPPERmRatBN7.2
Rnor_6.01941,509,348 - 41,509,527NCBIRnor6.0
Rnor_5.01952,337,431 - 52,337,610UniSTSRnor5.0
RGSC_v3.41940,023,162 - 40,023,341UniSTSRGSC3.4
Celera1937,512,316 - 37,512,495UniSTS
RH 3.4 Map19437.3UniSTS
Cytogenetic Map19q12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 8 27 103 48 48 30 25 30 5 146 61 93 38 60 18



Ensembl Acc Id: ENSRNOT00000022943   ⟹   ENSRNOP00000022943
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1938,114,435 - 38,141,438 (-)Ensembl
Rnor_6.0 Ensembl1941,482,728 - 41,509,658 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096342   ⟹   ENSRNOP00000090456
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1938,114,424 - 38,138,156 (-)Ensembl
RefSeq Acc Id: NM_053988   ⟹   NP_446440
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81955,023,849 - 55,050,858 (-)NCBI
mRatBN7.21938,114,435 - 38,141,438 (-)NCBI
Rnor_6.01941,482,743 - 41,509,617 (+)NCBI
Rnor_5.01952,310,641 - 52,337,700 (+)NCBI
RGSC_v3.41940,023,072 - 40,051,150 (-)RGD
Celera1937,512,226 - 37,538,062 (-)RGD
Sequence:
Protein RefSeqs NP_446440 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH87603 (Get FASTA)   NCBI Sequence Viewer  
  CAA47385 (Get FASTA)   NCBI Sequence Viewer  
  EDL92531 (Get FASTA)   NCBI Sequence Viewer  
  EDL92532 (Get FASTA)   NCBI Sequence Viewer  
  EDL92533 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000022943.2
GenBank Protein P47728 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_446440   ⟸   NM_053988
- UniProtKB: P47728 (UniProtKB/Swiss-Prot),   A6IZ54 (UniProtKB/TrEMBL),   A0A8I6ADK6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000022943   ⟸   ENSRNOT00000022943
Ensembl Acc Id: ENSRNOP00000090456   ⟸   ENSRNOT00000096342
EF-hand

Name Modeler Protein Id AA Range Protein Structure
AF-P47728-F1-model_v2 AlphaFold P47728 1-271 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13701129
Promoter ID:EPDNEW_R11653
Type:single initiation site
Name:Calb2_1
Description:calbindin 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01941,482,726 - 41,482,786EPDNEW


1 to 28 of 28 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-5694 BioCyc
Ensembl Genes ENSRNOG00000016977 Ensembl, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000022943.5 UniProtKB/Swiss-Prot
Gene3D-CATH EF-hand UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7312595 IMAGE-MGC_LOAD
InterPro CALB2 UniProtKB/Swiss-Prot
  Calbindin_Ca-bind UniProtKB/Swiss-Prot
  EF-hand-dom_pair UniProtKB/Swiss-Prot
  EF_Hand_1_Ca_BS UniProtKB/Swiss-Prot
  EF_hand_dom UniProtKB/Swiss-Prot
KEGG Report rno:117059 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105356 IMAGE-MGC_LOAD
NCBI Gene 117059 ENTREZGENE
PANTHER CALBINDIN UniProtKB/Swiss-Prot
  PTHR19972:SF4 UniProtKB/Swiss-Prot
Pfam EF-hand_1 UniProtKB/Swiss-Prot
  EF-hand_7 UniProtKB/Swiss-Prot
PhenoGen Calb2 PhenoGen
PROSITE EF_HAND_1 UniProtKB/Swiss-Prot
  EF_HAND_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000016977 RatGTEx
SMART EFh UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot
UniProt A0A8I6ADK6 ENTREZGENE, UniProtKB/TrEMBL
  A6IZ53_RAT UniProtKB/TrEMBL
  A6IZ54 ENTREZGENE, UniProtKB/TrEMBL
  A6IZ55_RAT UniProtKB/TrEMBL
  CALB2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 28 of 28 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-08-06 Calb2  calbindin 2      Symbol and Name status set to provisional 70820 PROVISIONAL