Calb2 (calbindin 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Calb2 (calbindin 2) Rattus norvegicus
Analyze
Symbol: Calb2
Name: calbindin 2
RGD ID: 620981
Description: Enables calcium ion binding activity. Predicted to be involved in intracellular calcium ion homeostasis; regulation of synaptic plasticity; and synaptic signaling. Located in cuticular plate and stereocilium. Is active in synapse. Orthologous to human CALB2 (calbindin 2); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH (R)-lipoic acid; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: calretinin; CR; MGC105356
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Eau8
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81955,023,849 - 55,050,858 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1955,023,838 - 55,057,952 (-)EnsemblGRCr8
mRatBN7.21938,114,435 - 38,141,438 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1938,114,424 - 38,141,438 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1944,920,886 - 44,947,919 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01945,574,230 - 45,601,269 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01947,883,801 - 47,910,840 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01941,482,743 - 41,509,617 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1941,482,728 - 41,509,658 (+)Ensemblrn6Rnor6.0
Rnor_5.01952,310,641 - 52,337,700 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41940,023,072 - 40,051,150 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1937,512,226 - 37,538,062 (-)NCBICelera
RGSC_v3.11940,027,952 - 40,056,031 (-)NCBI
Cytogenetic Map19q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(R)-lipoic acid  (EXP)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,4'-trichlorobiphenyl  (ISO)
2-hydroxypropanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
amphetamine  (ISO)
Ampullosporin  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
asbestos  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
butanal  (ISO)
Butylparaben  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
carmustine  (ISO)
cefaloridine  (EXP)
CGP 52608  (ISO)
chlordecone  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
cytarabine  (ISO)
DDE  (EXP)
DDT  (EXP)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
diethylstilbestrol  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (EXP,ISO)
ethylparaben  (ISO)
flusilazole  (EXP)
flutamide  (EXP)
hydroquinone  (ISO)
indometacin  (ISO)
ketamine  (EXP)
ketoconazole  (EXP)
L-ascorbic acid  (EXP)
lead diacetate  (EXP)
lead(0)  (EXP,ISO)
Licochalcone B  (ISO)
lipoic acid  (EXP)
maneb  (ISO)
methamphetamine  (EXP)
methimazole  (EXP)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
oxaliplatin  (ISO)
ozone  (ISO)
panobinostat  (ISO)
paraquat  (ISO)
PCB138  (EXP,ISO)
pentanal  (ISO)
picrotoxin  (EXP)
pirinixic acid  (EXP,ISO)
potassium dichromate  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
rotenone  (ISO)
S-nitrosoglutathione  (ISO)
SB 431542  (ISO)
simvastatin  (EXP)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sotorasib  (ISO)
sterigmatocystin  (EXP)
temozolomide  (ISO)
toluene  (EXP)
trametinib  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cuticular plate  (IDA,IEA)
cytosol  (IBA,IEA,ISO)
dendriole  (ISO,ISS)
dendrite  (IBA,IEA)
gap junction  (ISO)
neuronal cell body  (ISO)
nucleus  (IBA)
parallel fiber to Purkinje cell synapse  (ISO,ISS)
stereocilium  (IDA,IEA)
synapse  (EXP,IBA,IDA,IEA,IEP)
terminal bouton  (HDA,IBA)
vestibular calyx terminal  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. De novo expression of calretinin in trimethyltin-induced degeneration of developing rat hippocampus. Businaro R, etal., Brain Res Mol Brain Res 2002 Jan 31;98(1-2):141-4.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. The concentrations of calcium buffering proteins in mammalian cochlear hair cells. Hackney CM, etal., J Neurosci. 2005 Aug 24;25(34):7867-75.
4. Calretinin and CD34 immunoreactivity of the endometrial stroma in normal endometrium and change of the immunoreactivity in dysfunctional uterine bleeding with evidence of 'disordered endometrial stroma'. Mai KT, etal., Pathology. 2008 Aug;40(5):493-9.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. Structural and biochemical characterization of neuronal calretinin domain I-II (residues 1-100). Comparison to homologous calbindin D28k domain I-II (residues 1-93). Palczewska M, etal., Eur J Biochem. 2001 Dec;268(23):6229-37.
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. Cytosolic Ca2+ buffers. Schwaller B, Cold Spring Harb Perspect Biol. 2010 Nov;2(11):a004051. doi: 10.1101/cshperspect.a004051. Epub 2010 Oct 13.
12. Nucleotide sequence of rat calretinin cDNA. Strauss KI and Jacobowitz DM, Neurochem Int 1993 Jun;22(6):541-6.
13. Immunocytochemical detection of calretinin in the claustrum and endopiriform nucleus of the chinchilla. Szalak R, etal., Pol J Vet Sci. 2015;18(4):857-63. doi: 10.1515/pjvs-2015-0111.
14. Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins. Wilhelm BG, etal., Science. 2014 May 30;344(6187):1023-8. doi: 10.1126/science.1252884.
15. Distribution of calretinin, calbindin D28k, and parvalbumin in subcellular fractions of rat cerebellum: effects of calcium. Winsky L and Kuznicki J, J Neurochem. 1995 Jul;65(1):381-8.
Additional References at PubMed
PMID:1988053   PMID:7918640   PMID:12477932   PMID:12577320   PMID:12868005   PMID:14730585   PMID:15093134   PMID:15355314   PMID:15489334   PMID:17177263   PMID:17965879   PMID:18720478  
PMID:18769561   PMID:21080000   PMID:21394464   PMID:21835217   PMID:22037839   PMID:22221733   PMID:23273895   PMID:24134921   PMID:25730969   PMID:25813826   PMID:28131823   PMID:33040447  


Genomics

Comparative Map Data
Calb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81955,023,849 - 55,050,858 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1955,023,838 - 55,057,952 (-)EnsemblGRCr8
mRatBN7.21938,114,435 - 38,141,438 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1938,114,424 - 38,141,438 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1944,920,886 - 44,947,919 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01945,574,230 - 45,601,269 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01947,883,801 - 47,910,840 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01941,482,743 - 41,509,617 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1941,482,728 - 41,509,658 (+)Ensemblrn6Rnor6.0
Rnor_5.01952,310,641 - 52,337,700 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41940,023,072 - 40,051,150 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1937,512,226 - 37,538,062 (-)NCBICelera
RGSC_v3.11940,027,952 - 40,056,031 (-)NCBI
Cytogenetic Map19q12NCBI
CALB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381671,358,723 - 71,390,433 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1671,358,713 - 71,390,436 (+)Ensemblhg38GRCh38
GRCh371671,392,626 - 71,424,336 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361669,950,127 - 69,981,842 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341669,950,126 - 69,981,836NCBI
Celera1655,708,128 - 55,740,202 (+)NCBICelera
Cytogenetic Map16q22.2NCBI
HuRef1657,186,719 - 57,192,385 (+)NCBIHuRef
HuRef1657,160,840 - 57,186,546 (+)NCBIHuRef
CHM1_11672,805,453 - 72,837,193 (+)NCBICHM1_1
T2T-CHM13v2.01677,174,637 - 77,207,658 (+)NCBIT2T-CHM13v2.0
Calb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398110,869,158 - 110,894,844 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8110,864,134 - 110,894,842 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm388110,142,526 - 110,168,212 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8110,137,502 - 110,168,210 (-)Ensemblmm10GRCm38
MGSCv378112,666,438 - 112,692,106 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv368113,031,667 - 113,057,335 (-)NCBIMGSCv36mm8
Celera8114,365,078 - 114,391,219 (-)NCBICelera
Cytogenetic Map8D3NCBI
cM Map857.44NCBI
Calb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554844,075,067 - 4,103,559 (+)Ensembl
ChiLan1.0NW_0049554844,075,103 - 4,103,509 (+)NCBIChiLan1.0ChiLan1.0
CALB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21882,768,831 - 82,801,912 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11688,702,425 - 88,982,493 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01653,620,317 - 53,653,372 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11671,195,770 - 71,227,937 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1671,195,770 - 71,227,937 (+)EnsemblpanPan2panpan1.1
CALB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1577,178,158 - 77,205,663 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl577,177,951 - 77,205,671 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha577,139,985 - 77,167,208 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0577,616,925 - 77,644,159 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl577,616,951 - 77,644,096 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1577,437,354 - 77,464,585 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0577,260,506 - 77,287,715 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0577,759,356 - 77,786,581 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Calb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934937,217,095 - 37,244,688 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647522,341,822 - 22,372,609 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647522,344,416 - 22,372,015 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CALB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl614,391,857 - 14,420,663 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1614,392,220 - 14,420,663 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2613,904,114 - 13,933,267 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CALB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1554,503,635 - 54,538,304 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl554,504,082 - 54,538,441 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604717,312,991 - 17,345,343 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Calb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474613,548,540 - 13,578,501 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474613,549,339 - 13,577,929 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Calb2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11729,846,727 - 29,873,200 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Calb2
141 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:88
Count of miRNA genes:73
Interacting mature miRNAs:83
Transcripts:ENSRNOT00000022943
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)191922068964220689Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)194622677874246245Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194438513474246245Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)192010930665109306Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)194172254674246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat

Markers in Region
D19Rat71  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81955,039,510 - 55,039,721 (+)Marker Load Pipeline
mRatBN7.21938,130,095 - 38,130,307 (-)MAPPERmRatBN7.2
Rnor_6.01941,493,877 - 41,494,088NCBIRnor6.0
Rnor_5.01952,321,960 - 52,322,171UniSTSRnor5.0
RH 3.4 Map19437.4RGD
RH 3.4 Map19437.4UniSTS
RH 2.0 Map19481.8RGD
SHRSP x BN Map1927.8698RGD
Cytogenetic Map19q12UniSTS
X73985  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21938,114,703 - 38,114,871 (-)MAPPERmRatBN7.2
Rnor_6.01941,509,181 - 41,509,348NCBIRnor6.0
Rnor_5.01952,337,264 - 52,337,431UniSTSRnor5.0
RGSC_v3.41940,023,341 - 40,023,508UniSTSRGSC3.4
Celera1937,512,495 - 37,512,662UniSTS
Cytogenetic Map19q12UniSTS
RH138609  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21938,114,524 - 38,114,704 (-)MAPPERmRatBN7.2
Rnor_6.01941,509,348 - 41,509,527NCBIRnor6.0
Rnor_5.01952,337,431 - 52,337,610UniSTSRnor5.0
RGSC_v3.41940,023,162 - 40,023,341UniSTSRGSC3.4
Celera1937,512,316 - 37,512,495UniSTS
RH 3.4 Map19437.3UniSTS
Cytogenetic Map19q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
12 8 31 130 48 48 30 41 30 5 188 82 1 119 56 68 18 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000022943   ⟹   ENSRNOP00000022943
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1955,023,838 - 55,057,952 (-)Ensembl
mRatBN7.2 Ensembl1938,114,435 - 38,141,438 (-)Ensembl
Rnor_6.0 Ensembl1941,482,728 - 41,509,658 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096342   ⟹   ENSRNOP00000090456
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1938,114,424 - 38,138,156 (-)Ensembl
RefSeq Acc Id: NM_053988   ⟹   NP_446440
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81955,023,849 - 55,050,858 (-)NCBI
mRatBN7.21938,114,435 - 38,141,438 (-)NCBI
Rnor_6.01941,482,743 - 41,509,617 (+)NCBI
Rnor_5.01952,310,641 - 52,337,700 (+)NCBI
RGSC_v3.41940,023,072 - 40,051,150 (-)RGD
Celera1937,512,226 - 37,538,062 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_446440 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH87603 (Get FASTA)   NCBI Sequence Viewer  
  CAA47385 (Get FASTA)   NCBI Sequence Viewer  
  EDL92531 (Get FASTA)   NCBI Sequence Viewer  
  EDL92532 (Get FASTA)   NCBI Sequence Viewer  
  EDL92533 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000022943.2
GenBank Protein P47728 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_446440   ⟸   NM_053988
- UniProtKB: P47728 (UniProtKB/Swiss-Prot),   A6IZ54 (UniProtKB/TrEMBL),   A0A8I6ADK6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000022943   ⟸   ENSRNOT00000022943
Ensembl Acc Id: ENSRNOP00000090456   ⟸   ENSRNOT00000096342
Protein Domains
EF-hand

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P47728-F1-model_v2 AlphaFold P47728 1-271 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701129
Promoter ID:EPDNEW_R11653
Type:single initiation site
Name:Calb2_1
Description:calbindin 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01941,482,726 - 41,482,786EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620981 AgrOrtholog
BioCyc Gene G2FUF-5694 BioCyc
Ensembl Genes ENSRNOG00000016977 Ensembl, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000022943.5 UniProtKB/Swiss-Prot
Gene3D-CATH EF-hand UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7312595 IMAGE-MGC_LOAD
InterPro CALB2 UniProtKB/Swiss-Prot
  Calbindin_Ca-bind UniProtKB/Swiss-Prot
  EF-hand-dom_pair UniProtKB/Swiss-Prot
  EF_Hand_1_Ca_BS UniProtKB/Swiss-Prot
  EF_hand_dom UniProtKB/Swiss-Prot
KEGG Report rno:117059 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105356 IMAGE-MGC_LOAD
NCBI Gene 117059 ENTREZGENE
PANTHER CALBINDIN UniProtKB/Swiss-Prot
  PTHR19972:SF4 UniProtKB/Swiss-Prot
Pfam EF-hand_1 UniProtKB/Swiss-Prot
  EF-hand_7 UniProtKB/Swiss-Prot
PhenoGen Calb2 PhenoGen
PROSITE EF_HAND_1 UniProtKB/Swiss-Prot
  EF_HAND_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000016977 RatGTEx
SMART EFh UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot
UniProt A0A8I6ADK6 ENTREZGENE
  A6IZ53_RAT UniProtKB/TrEMBL
  A6IZ54 ENTREZGENE, UniProtKB/TrEMBL
  A6IZ55_RAT UniProtKB/TrEMBL
  CALB2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-08-06 Calb2  calbindin 2      Symbol and Name status set to provisional 70820 PROVISIONAL