Khdrbs3 (KH RNA binding domain containing, signal transduction associated 3) - Rat Genome Database

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Gene: Khdrbs3 (KH RNA binding domain containing, signal transduction associated 3) Rattus norvegicus
Analyze
Symbol: Khdrbs3
Name: KH RNA binding domain containing, signal transduction associated 3
RGD ID: 620921
Description: Enables single-stranded RNA binding activity. Involved in mRNA processing; regulation of RNA splicing; and spermatogenesis. Located in nucleus. Orthologous to human KHDRBS3 (KH RNA binding domain containing, signal transduction associated 3); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Etle; etoile, Sam68-like protein SLM-2; KH domain containing, RNA binding, signal transduction associated 3; KH domain-containing, RNA-binding, signal transduction-associated protein 3; rSLM-2; sam68-like mammalian protein 2; SLM-2; Slm2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87102,726,628 - 102,884,545 (+)NCBIGRCr8
mRatBN7.27100,837,707 - 100,995,644 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7100,837,934 - 100,988,460 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7102,574,664 - 102,718,063 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07104,776,349 - 104,919,747 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07104,717,109 - 104,860,445 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07110,031,819 - 110,179,475 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7110,031,696 - 110,179,468 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07109,965,269 - 110,111,230 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47106,539,015 - 106,614,745 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17106,573,244 - 106,648,972 (+)NCBI
Celera797,331,783 - 97,474,062 (+)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IDA,IEA,ISO)
protein-containing complex  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Heterogeneous nuclear ribonucleoprotein G regulates splice site selection by binding to CC(A/C)-rich regions in pre-mRNA. Heinrich B, etal., J Biol Chem. 2009 May 22;284(21):14303-15. Epub 2009 Mar 12.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. The STAR/GSG family protein rSLM-2 regulates the selection of alternative splice sites. Stoss O, etal., J Biol Chem 2001 Mar 23;276(12):8665-73.
9. p59(fyn)-mediated phosphorylation regulates the activity of the tissue-specific splicing factor rSLM-1. Stoss O, etal., Mol Cell Neurosci 2004 Sep;27(1):8-21.
10. T-STAR/ETOILE: a novel relative of SAM68 that interacts with an RNA-binding protein implicated in spermatogenesis. Venables JP, etal., Hum Mol Genet. 1999 Jun;8(6):959-69.
Additional References at PubMed
PMID:10749975   PMID:19561594   PMID:22196734   PMID:22681889  


Genomics

Comparative Map Data
Khdrbs3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87102,726,628 - 102,884,545 (+)NCBIGRCr8
mRatBN7.27100,837,707 - 100,995,644 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7100,837,934 - 100,988,460 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7102,574,664 - 102,718,063 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07104,776,349 - 104,919,747 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07104,717,109 - 104,860,445 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07110,031,819 - 110,179,475 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7110,031,696 - 110,179,468 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07109,965,269 - 110,111,230 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47106,539,015 - 106,614,745 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17106,573,244 - 106,648,972 (+)NCBI
Celera797,331,783 - 97,474,062 (+)NCBICelera
Cytogenetic Map7q34NCBI
KHDRBS3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388135,457,456 - 135,656,516 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8135,457,456 - 135,656,722 (+)EnsemblGRCh38hg38GRCh38
GRCh378136,469,699 - 136,659,853 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368136,538,898 - 136,729,031 (+)NCBINCBI36Build 36hg18NCBI36
Build 348136,538,897 - 136,729,028NCBI
Celera8132,642,482 - 132,831,891 (+)NCBICelera
Cytogenetic Map8q24.23NCBI
HuRef8131,785,096 - 131,974,740 (+)NCBIHuRef
CHM1_18136,511,650 - 136,701,600 (+)NCBICHM1_1
T2T-CHM13v2.08136,575,311 - 136,774,451 (+)NCBIT2T-CHM13v2.0
Khdrbs3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391568,800,155 - 68,973,064 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1568,800,269 - 68,973,060 (+)EnsemblGRCm39 Ensembl
GRCm381568,928,392 - 69,101,794 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1568,928,420 - 69,101,211 (+)EnsemblGRCm38mm10GRCm38
MGSCv371568,758,850 - 68,923,949 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361568,758,089 - 68,923,188 (+)NCBIMGSCv36mm8
Celera1570,448,119 - 70,614,372 (+)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1530.36NCBI
Khdrbs3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554619,751,057 - 9,915,943 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554619,751,057 - 9,926,211 (+)NCBIChiLan1.0ChiLan1.0
KHDRBS3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27152,848,167 - 153,047,670 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18128,381,719 - 128,580,807 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08132,131,953 - 132,331,310 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18135,084,505 - 135,282,770 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8135,084,505 - 135,282,766 (+)Ensemblpanpan1.1panPan2
KHDRBS3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11331,397,501 - 31,583,198 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1331,392,842 - 31,605,257 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1331,374,685 - 31,559,991 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01331,768,586 - 31,954,402 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1331,763,092 - 31,954,398 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11331,490,283 - 31,675,703 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01331,584,104 - 31,769,857 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01331,934,428 - 32,120,024 (+)NCBIUU_Cfam_GSD_1.0
Khdrbs3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244053036,806,218 - 6,977,811 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647014,239,841 - 14,403,916 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647014,232,114 - 14,403,910 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KHDRBS3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl46,282,076 - 6,446,389 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.146,289,577 - 6,446,494 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.246,127,960 - 6,284,514 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KHDRBS3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18129,814,228 - 130,044,479 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8129,911,686 - 130,035,258 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603910,035,579 - 10,236,195 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Khdrbs3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473520,425,148 - 20,586,626 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473520,415,996 - 20,586,632 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Khdrbs3
1131 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:85
Count of miRNA genes:62
Interacting mature miRNAs:77
Transcripts:ENSRNOT00000012753
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)762004452101773158Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)780221299112308525Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)762004452101773158Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
1298525Cm1Cardiac mass QTL 12.7heart mass (VT:0007028)heart wet weight (CMO:0000069)799736187103146217Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)761074194106074194Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)780221299109401111Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)753612714103945643Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
2317035Aia16Adjuvant induced arthritis QTL 162.71joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)759238038104238038Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)794811085116738842Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)793595647106839474Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
10450828Scl79Serum cholesterol level QTL 793.50.001blood HDL cholesterol amount (VT:0000184)blood low density lipoprotein cholesterol level (CMO:0000053)789867376101773158Rat

Markers in Region
D7Rat100  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27100,865,992 - 100,866,189 (+)MAPPERmRatBN7.2
Rnor_6.07110,056,517 - 110,056,713NCBIRnor6.0
Rnor_5.07109,990,044 - 109,990,240UniSTSRnor5.0
Celera797,353,709 - 97,353,923UniSTS
RH 3.4 Map7693.3UniSTS
RH 3.4 Map7693.3RGD
RH 2.0 Map7526.5RGD
SHRSP x BN Map756.84RGD
FHH x ACI Map747.8299RGD
Cytogenetic Map7q34UniSTS
D7Rat53  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27100,874,472 - 100,874,685 (+)MAPPERmRatBN7.2
Rnor_6.07110,065,540 - 110,065,752NCBIRnor6.0
Rnor_5.07109,998,231 - 109,998,443UniSTSRnor5.0
Celera797,362,214 - 97,362,426UniSTS
RH 3.4 Map7693.3UniSTS
RH 3.4 Map7693.3RGD
RH 2.0 Map7533.9RGD
FHH x ACI Map747.8299RGD
Cytogenetic Map7q34UniSTS
D7Rat159  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27100,963,583 - 100,963,703 (+)MAPPERmRatBN7.2
Rnor_6.07110,154,795 - 110,154,914NCBIRnor6.0
Rnor_5.07110,086,417 - 110,086,536UniSTSRnor5.0
RGSC_v3.47106,587,929 - 106,588,048UniSTSRGSC3.4
RGSC_v3.47106,587,928 - 106,588,048RGDRGSC3.4
RGSC_v3.17106,622,158 - 106,622,278RGD
FHH x ACI Map747.8299UniSTS
FHH x ACI Map747.8299RGD
Cytogenetic Map7q34UniSTS
BE119914  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27100,839,897 - 100,840,061 (+)MAPPERmRatBN7.2
Rnor_6.07110,033,656 - 110,033,819NCBIRnor6.0
Rnor_5.07109,967,106 - 109,967,269UniSTSRnor5.0
Celera797,333,669 - 97,333,832UniSTS
RH 3.4 Map7695.1UniSTS
Cytogenetic Map7q34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 43 16 6 9 6 74 23 41 10
Low 2 41 35 10 35 8 11 12 1 8
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000012753   ⟹   ENSRNOP00000012753
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7100,837,934 - 100,988,460 (+)Ensembl
Rnor_6.0 Ensembl7110,031,696 - 110,179,468 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000097337   ⟹   ENSRNOP00000096934
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7100,837,934 - 100,988,460 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000112404   ⟹   ENSRNOP00000076402
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7100,838,339 - 100,988,460 (+)Ensembl
RefSeq Acc Id: NM_022249   ⟹   NP_071585
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87102,726,843 - 102,877,372 (+)NCBI
mRatBN7.27100,837,934 - 100,988,467 (+)NCBI
Rnor_6.07110,031,819 - 110,179,475 (+)NCBI
Rnor_5.07109,965,269 - 110,111,230 (+)NCBI
RGSC_v3.47106,539,015 - 106,614,745 (+)RGD
Celera797,331,783 - 97,474,062 (+)RGD
Sequence:
RefSeq Acc Id: XM_063264202   ⟹   XP_063120272
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87102,756,629 - 102,877,372 (+)NCBI
RefSeq Acc Id: XM_063264203   ⟹   XP_063120273
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87102,762,422 - 102,877,372 (+)NCBI
RefSeq Acc Id: XM_063264204   ⟹   XP_063120274
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87102,727,433 - 102,877,372 (+)NCBI
RefSeq Acc Id: XR_005486718
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87102,726,628 - 102,884,545 (+)NCBI
mRatBN7.27100,837,707 - 100,995,644 (+)NCBI
RefSeq Acc Id: XR_010053039
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87102,727,525 - 102,884,545 (+)NCBI
RefSeq Acc Id: NP_071585   ⟸   NM_022249
- UniProtKB: Q9JLP1 (UniProtKB/Swiss-Prot),   F1LMN8 (UniProtKB/TrEMBL),   A6HRU0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000012753   ⟸   ENSRNOT00000012753
RefSeq Acc Id: ENSRNOP00000096934   ⟸   ENSRNOT00000097337
RefSeq Acc Id: ENSRNOP00000076402   ⟸   ENSRNOT00000112404
RefSeq Acc Id: XP_063120274   ⟸   XM_063264204
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063120272   ⟸   XM_063264202
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063120273   ⟸   XM_063264203
- Peptide Label: isoform X2
Protein Domains
K Homology   KH   KHDRBS Qua1   Sam68 tyrosine-rich

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JLP1-F1-model_v2 AlphaFold Q9JLP1 1-346 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620921 AgrOrtholog
BioCyc Gene G2FUF-33092 BioCyc
Ensembl Genes ENSRNOG00000009539 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012753 ENTREZGENE
  ENSRNOT00000012753.8 UniProtKB/TrEMBL
  ENSRNOT00000097337.1 UniProtKB/TrEMBL
  ENSRNOT00000112404.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1370.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro BBP-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KH_dom_type_1_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Qua1_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sam68-YY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:64015 UniProtKB/Swiss-Prot
NCBI Gene 64015 ENTREZGENE
PANTHER KH DOMAIN-CONTAINING, RNA-BINDING, SIGNAL TRANSDUCTION-ASSOCIATED PROTEIN 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11208 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Qua1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sam68-YY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB KHDRBS3 RGD
PhenoGen Khdrbs3 PhenoGen
RatGTEx ENSRNOG00000009539 RatGTEx
SMART SM00322 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54791 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5YBJ1_RAT UniProtKB/TrEMBL
  A0A8I6AMW6_RAT UniProtKB/TrEMBL
  A6HRU0 ENTREZGENE, UniProtKB/TrEMBL
  A6HRU1_RAT UniProtKB/TrEMBL
  A6HRU2_RAT UniProtKB/TrEMBL
  F1LMN8 ENTREZGENE, UniProtKB/TrEMBL
  KHDR3_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-01 Khdrbs3  KH RNA binding domain containing, signal transduction associated 3  Khdrbs3  KH domain containing, RNA binding, signal transduction associated 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Khdrbs3  KH domain containing, RNA binding, signal transduction associated 3    etoile, Sam68-like protein SLM-2  Name updated 1299863 APPROVED
2004-09-10 Khdrbs3  etoile, Sam68-like protein SLM-2  Etle    Symbol and Name updated 1299863 APPROVED
2002-08-07 Etle  etoile, Sam68-like protein SLM-2      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_product member of the STAR (signal transduction and activation of RNA) protein family 632715