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Gene: Tcn2 (transcobalamin 2) Rattus norvegicus

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Symbol:

Tcn2

Name:

transcobalamin 2

RGD ID:

620681

Description:

Enables cobalamin binding activity. Predicted to be involved in cobalamin transport. Located in extracellular space. Human ortholog(s) of this gene implicated in Parkinson's disease; megaloblastic anemia; and transcobalamin II deficiency. Orthologous to human TCN2 (transcobalamin 2); INTERACTS WITH (R,R,R)-alpha-tocopherol; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 17alpha-ethynylestradiol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

TC II; TC-2; Tc2; TCII; Tcn2p; transcobalamin II; transcobalamin II precursor; transcobalamin-2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TCN2 (transcobalamin 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Tcn2 (transcobalamin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tcn2 (transcobalamin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TCN2 (transcobalamin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TCN2 (transcobalamin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tcn2 (transcobalamin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TCN2 (transcobalamin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TCN2 (transcobalamin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tcn2 (transcobalamin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Tcn2 (transcobalamin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	MYBPH (myosin binding protein H)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Tcn2 (transcobalamin 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	TCN2 (transcobalamin 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	TCN2 (transcobalamin 2)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tcn2 (transcobalamin II)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG3556	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	tcn2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	tcn2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	83,036,935 - 83,052,187 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	83,036,935 - 83,051,552 (-)	Ensembl				GRCr8
mRatBN7.2	14	78,813,343 - 78,828,549 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	78,813,343 - 78,828,489 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	83,254,381 - 83,269,024 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	84,494,463 - 84,509,106 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	80,940,036 - 80,954,783 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	84,173,992 - 84,189,299 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	84,174,138 - 84,189,266 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	84,857,864 - 84,873,021 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	84,579,191 - 84,593,641 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	77,725,351 - 77,739,968 (-)	NCBI		Celera
RGSC_v3.1	14	84,598,335 - 84,612,786 (-)	NCBI
Cytogenetic Map	14	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute lymphoblastic leukemia (ISO)

acute myeloid leukemia (ISO)

adenoma (ISO)

autistic disorder (ISO)

Blast Crisis (ISO)

cleft lip (ISO)

Colorectal Neoplasms (ISO)

COVID-19 (ISO)

cryoglobulinemia (ISO)

esophagus squamous cell carcinoma (ISO)

genetic disease (ISO)

Leukoencephalopathies (ISO)

megaloblastic anemia (ISO)

pancytopenia (ISO)

Parkinson's disease (ISO)

Prostatic Neoplasms (ISO)

Refractory Anemia (ISO)

transcobalamin II deficiency (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

(R,R,R)-alpha-tocopherol (EXP)

1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane (EXP)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP,ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-hydroxypropanoic acid (ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

amitrole (EXP)

ammonium chloride (EXP)

amphetamine (EXP)

antirheumatic drug (ISO)

beauvericin (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

buta-1,3-diene (ISO)

butanal (ISO)

C60 fullerene (EXP)

cadmium dichloride (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chloroprene (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

clofibrate (ISO)

crocidolite asbestos (ISO)

Cuprizon (EXP)

cyanocob(III)alamin (ISO)

dexamethasone (ISO)

doxorubicin (ISO)

enniatin (ISO)

ethanol (ISO)

fluoxetine (ISO)

flutamide (EXP)

folic acid (ISO)

gentamycin (EXP)

inulin (ISO)

isoprenaline (ISO)

L-ascorbic acid (EXP)

methimazole (EXP)

methotrexate (ISO)

methylseleninic acid (ISO)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (EXP,ISO)

perfluorooctanoic acid (EXP)

phenobarbital (EXP)

rac-lactic acid (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (EXP,ISO)

Soman (EXP)

succimer (ISO)

tamoxifen (ISO)

tetrachloromethane (EXP,ISO)

theophylline (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (EXP)

tremolite asbestos (ISO)

trichloroethene (EXP)

tungsten (ISO)

valproic acid (ISO)

vancomycin (ISO)

zidovudine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cobalamin transport (IBA,IEA,ISO,ISS,TAS)

cobalt ion transport (IEA)

monoatomic ion transport (IEA)

Cellular Component

external side of plasma membrane (IEA,ISO)

extracellular region (IEA)

extracellular space (IBA,IDA,IEA,ISO)

Molecular Function

cargo receptor ligand activity (IEA,ISO)

cobalamin binding (IBA,IDA,IEA,ISO)

metal ion binding (IEA)

molecular carrier activity (IEA,ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transcobalamin II. A specific marker of renal involvement in essential mixed cryoglobulinemia.	Biosca M, etal., Nephron. 1987;45(3):255-6.
2.	Transfer of cobalamin from intrinsic factor to transcobalamin II.	Brada N, etal., J Nutr Biochem. 2001 Apr;12(4):200-206.
3.	Binding of vitamin B12--rat transcobalamin II and free vitamin B12 to plasma membranes isolated from rat liver.	Fiedler-Nagy C, etal., Br J Haematol. 1975 Nov;31(3):311-21.
4.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5.	[Transcobalamin II levels in blood plasma of children with acute leukemia].	Gudkova MV, etal., Gematol Transfuziol. 1996 Mar-Apr;41(2):10-3.
6.	Identification of two mutant alleles of transcobalamin II in an affected family.	Li N, etal., Hum Mol Genet. 1994 Oct;3(10):1835-40.
7.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
8.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
9.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
10.	Vitamin B12-impaired metabolism produces apoptosis and Parkinson phenotype in rats expressing the transcobalamin-oleosin chimera in substantia nigra.	Orozco-Barrios CE, etal., PLoS One. 2009 Dec 21;4(12):e8268. doi: 10.1371/journal.pone.0008268.
11.	A transcobalamin gene polymorphism and the risk of venous thrombosis. The BRATROS (Brazilian Thrombosis Study).	Pereira AC, etal., Thromb Res. 2006 Mar 10;.
12.	GOA pipeline	RGD automated data pipeline
13.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
15.	Transcobalamin II and its cell surface receptor.	Seetharam B and Li N, Vitam Horm 2000;59:337-66.
16.	No association between the MTHFR A1298C and transcobalamin C776G genetic polymorphisms and hyperhomocysteinemia in thrombotic disease.	Zetterberg H, etal., Thromb Res. 2002 Nov 1;108(2-3):127-31.
17.	The three transcobalamins in myeloproliferative disorders and acute leukaemia.	Zittoun J, etal., Br J Haematol. 1975 Nov;31(3):287-98.

Additional References at PubMed

PMID:8443384	PMID:15488467	PMID:16537422	PMID:23376485	PMID:24006456	PMID:27411955

Genomics

Comparative Map Data

Tcn2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	83,036,935 - 83,052,187 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	83,036,935 - 83,051,552 (-)	Ensembl				GRCr8
mRatBN7.2	14	78,813,343 - 78,828,549 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	78,813,343 - 78,828,489 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	83,254,381 - 83,269,024 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	84,494,463 - 84,509,106 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	80,940,036 - 80,954,783 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	84,173,992 - 84,189,299 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	84,174,138 - 84,189,266 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	84,857,864 - 84,873,021 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	84,579,191 - 84,593,641 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	77,725,351 - 77,739,968 (-)	NCBI		Celera
RGSC_v3.1	14	84,598,335 - 84,612,786 (-)	NCBI
Cytogenetic Map	14	q21	NCBI

TCN2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	22	30,607,174 - 30,627,271 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	22	30,607,003 - 30,627,631 (+)	Ensembl			hg38	GRCh38
GRCh37	22	31,003,161 - 31,023,258 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	22	29,333,161 - 29,353,047 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	22	29,327,714 - 29,347,601	NCBI
Celera	22	14,802,947 - 14,823,211 (+)	NCBI		Celera
Cytogenetic Map	22	q12.2	NCBI
HuRef	22	13,965,286 - 13,985,550 (+)	NCBI		HuRef
CHM1_1	22	30,962,510 - 30,982,925 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	22	31,070,745 - 31,090,856 (+)	NCBI		T2T-CHM13v2.0

Tcn2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	3,867,077 - 3,882,078 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	3,867,192 - 3,882,159 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	11	3,917,077 - 3,932,078 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	3,917,192 - 3,932,159 (-)	Ensembl			mm10	GRCm38
MGSCv37	11	3,817,080 - 3,832,081 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	11	3,817,193 - 3,831,586 (-)	NCBI		MGSCv36	mm8
Celera	11	4,411,604 - 4,426,160 (-)	NCBI		Celera
Cytogenetic Map	11	A1	NCBI
cM Map	11	2.76	NCBI

Tcn2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955455	4,826,694 - 4,849,613 (+)	Ensembl
ChiLan1.0	NW_004955455	4,827,030 - 4,849,810 (+)	NCBI	ChiLan1.0	ChiLan1.0

TCN2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	23	40,566,388 - 40,586,364 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	22	43,264,719 - 43,284,822 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	22	11,635,107 - 11,655,137 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	22	29,435,506 - 29,455,494 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	22	29,435,517 - 29,455,494 (+)	Ensembl			panPan2	panpan1.1

TCN2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	23,693,664 - 23,710,342 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	23,693,773 - 23,709,832 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	23,564,400 - 23,581,079 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	24,077,931 - 24,094,603 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	24,078,013 - 24,094,603 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	23,779,098 - 23,796,016 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	24,042,019 - 24,058,648 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	24,102,548 - 24,119,234 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Tcn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	116,620,289 - 116,636,698 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936904	95,542 - 113,985 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936904	97,535 - 113,886 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TCN2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	47,502,715 - 47,515,965 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	47,496,245 - 47,515,966 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	50,598,159 - 50,627,102 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TCN2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	19	13,489,849 - 13,511,360 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	19	13,490,645 - 13,511,810 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666045	112,616,329 - 112,637,803 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tcn2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624747	6,971,289 - 6,987,440 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624747	6,970,707 - 6,987,946 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Tcn2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	11	72,929,384 - 72,944,549 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Tcn2
192 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	48
Count of miRNA genes:	42
Interacting mature miRNAs:	45
Transcripts:	ENSRNOT00000005934
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
9590294	Uminl4	Urine mineral level QTL 4	5.66	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	14	59848686	104848686	Rat
1582236	Gluco22	Glucose level QTL 22	3.3	0.0164	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	77640071	96755654	Rat
2300197	Scl59	Serum cholesterol level QTL 59			blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	14	77914838	104348525	Rat
70214	Niddm28	Non-insulin dependent diabetes mellitus QTL 28	4.06		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	39009444	84009444	Rat
70153	Bp59	Blood pressure QTL 59	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	14	72970210	87582095	Rat
70187	Pancm5	Pancreatic morphology QTL 5	16.7		pancreas mass (VT:0010144)	pancreas weight to body weight ratio (CMO:0000630)	14	30674469	85041098	Rat
631523	Pia13	Pristane induced arthritis QTL 13	3.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	14	33424686	102238540	Rat
1582259	Gluco23	Glucose level QTL 23	3.1	0.0008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	74255551	109089856	Rat
1582197	Gluco27	Glucose level QTL 27	3.4	0.0006	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	77640071	96755654	Rat
634328	Hc5	Hypercalciuria QTL 5	2.3		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	14	62398852	107398852	Rat
1582250	Gluco26	Glucose level QTL 26	3.3	0.0009	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	77640071	100078267	Rat
2317879	Alcrsp27	Alcohol response QTL 27	3.3	0.63	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	14	60854936	105854936	Rat
1641900	Alcrsp11	Alcohol response QTL 11			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	14	74255551	109089856	Rat
631839	Niddm37	Non-insulin dependent diabetes mellitus QTL 37	3.37		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	11334716	100078267	Rat
1582255	Gluco29	Glucose level QTL 29	3.1	0.0025	blood glucose amount (VT:0000188)	absolute change in blood glucose level area under curve (CMO:0002034)	14	77640071	96755654	Rat
9589034	Epfw11	Epididymal fat weight QTL 11	6	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	14	59848686	104848686	Rat
1582209	Gluco20	Glucose level QTL 20	3.8	0.0005	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	77640071	96755654	Rat
1300136	Rf22	Renal function QTL 22	3.9		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	14	42616258	99224555	Rat
1549834	Scl45	Serum cholesterol level QTL 45	5.8		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	14	65920283	99224555	Rat
738037	Hcas6	Hepatocarcinoma susceptibility QTL 6	2.93		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	14	39411170	87582095	Rat

Markers in Region

AW208754

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	78,813,667 - 78,813,756 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	84,174,317 - 84,174,405	NCBI	Rnor6.0
Rnor_5.0	14	84,858,042 - 84,858,130	UniSTS	Rnor5.0
RGSC_v3.4	14	84,579,367 - 84,579,455	UniSTS	RGSC3.4
Celera	14	77,725,676 - 77,725,764	UniSTS
Cytogenetic Map	14	q21	UniSTS

BE099486

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	78,823,875 - 78,824,030 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	84,184,671 - 84,184,825	NCBI	Rnor6.0
Rnor_5.0	14	84,868,396 - 84,868,550	UniSTS	Rnor5.0
RGSC_v3.4	14	84,589,575 - 84,589,729	UniSTS	RGSC3.4
Celera	14	77,735,884 - 77,736,038	UniSTS
RH 3.4 Map	14	543.6	UniSTS
Cytogenetic Map	14	q21	UniSTS

RH127671

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	78,813,622 - 78,813,839 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	84,174,272 - 84,174,488	NCBI	Rnor6.0
Rnor_5.0	14	84,857,997 - 84,858,213	UniSTS	Rnor5.0
RGSC_v3.4	14	84,579,322 - 84,579,538	UniSTS	RGSC3.4
Celera	14	77,725,631 - 77,725,847	UniSTS
RH 3.4 Map	14	545.2	UniSTS
Cytogenetic Map	14	q21	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	164	91	90	59	92	59	6	356	192	11	143	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_022534	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006251366	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006251367	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006251368	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006251370	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599370	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599371	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF054810	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473963	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000005934 ⟹ ENSRNOP00000005934

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	83,036,935 - 83,051,552 (-)	Ensembl
mRatBN7.2 Ensembl	14	78,813,492 - 78,828,489 (-)	Ensembl
Rnor_6.0 Ensembl	14	84,174,138 - 84,189,266 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093962 ⟹ ENSRNOP00000077856

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	83,036,935 - 83,048,556 (-)	Ensembl
mRatBN7.2 Ensembl	14	78,813,343 - 78,824,964 (-)	Ensembl

RefSeq Acc Id:

NM_022534 ⟹ NP_071979

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	83,036,935 - 83,051,552 (-)	NCBI
mRatBN7.2	14	78,813,343 - 78,827,960 (-)	NCBI
Rnor_6.0	14	84,173,992 - 84,188,755 (-)	NCBI
Rnor_5.0	14	84,857,864 - 84,873,021 (-)	NCBI
RGSC_v3.4	14	84,579,191 - 84,593,641 (-)	RGD
Celera	14	77,725,351 - 77,739,968 (-)	NCBI

Sequence:

show sequence

TGACAAGTTGCTGTCAGACAAGCCCTCAAGGCGGGTTCCAGGAGTCTCTCACCTCCCACCTGTG
CCTGCCATGGAGCTCCTGAAGGCGCTGCTACTCCTGTCTGGAGTCCTCGGGGCTCTTGCTGAAT
TCTGTGTAATACCAAAGATGGACGGCCAGCTGGTAGAGAAGCTGGGCCAGCGTCTCTTACCTTG
GATGGATCGGCTTTCCTCAGAGCAGTTGAACCCCAGCATCTACGTCGGCCTGCGGCTTTCCAGC
ATGCAGGCTGGGACCAAGGAGAACCTCTACCTTCACAACCTCAAACTCCATTACCAGCAGTGCC
TCCTGCGGTCCACCTCGAGTGATGATAACAGTGGTTGCCAGACTAAGATTTCTGGGGGCAGCTT
GGCCCTCTACCTGCTTGCTCTCAGGGCCAACTGTGAGCTCCTGGGGAGCCGAAAGGGTGACAGG
ATGGTCTCACAGCTCAAGTGGTTCTTGGAGGATGAGAAGAAGGCCATTGGGCACCATCATGAAG
GCCACCCCCACACCAGCTATTACCAGTATGGCCTCAGTATCCTGGCCCTGTGCGTCCACCGGAA
GCGGGTCCATGACAGTGTGGTGGGCAAGCTCCTGTATGCTGTTGAACATGACTACTTTACCTAC
CAGGGCCACCTCTCTGTGGACACAGAAGCCATGGCCGGCTTGGCCTTCACCTGTTTGGAACGAT
TCAATTTCAACTCTGACCTGAGACCACGGATCACCACGGCCATCGAGACAGTGCGAGAGAAGAT
CCTGAAGGCCCAGGCCCCTGAGGGCTACTTTGGAAATATCTATAGCACTCCGCTGGCACTACAG
ATGCTAATGACCTCTCCTGGGGTAGGGCTGGGCCCAGCTTGCCTCAAGGCAAGGAAATCCCTGC
TGCTCAGCCTACAGGATGGAGCCTTCCAGAATCCTATGATGATTTCCCAGCTGCTACCCGTCCT
GAACCACAAGACCTACTTGAATCTTATCTCCCCAGACTGCCAGGCACCCAGGGTCATGTTGGTG
CCCGCCACTGAGGACCCTGTCCACTTGTCAGAAGTCAGCGTCACGCTGAAGGTCTCCAGTGTCT
TGCCACCATATGAACGAACAGTTTCCGTCTTTGCTGGGGCCTCCTTGGAAGATGTCCTGAAGAG
GGCGCGAGACCTTGGAGAATTCACGTATGGGACCCAGGCCTCCTTGTCAGGTCCCTACCTGACA
TCCGTACTAGGGAAAGAAGCTGGGGATCGAGAATACTGGCAGCTTCTCCGAGTCCCTGATACCC
CTCTGCTACAAGGCATTGCTGACTACAAACCCAAGAACGGGGAAACCATCGAATTGCGGCTAGT
TAGATGGTAGCCCTAGGCTCCCTCCTGATGTCTTCGGACCCTGCTGCCACCTCAAGTGCGCTTG
GAACAATGTCCCCCAGATCACCTCAGCTAACTTCCCAAAGAGGACCTAAGCCACTGTCCACCTT
AGAGCAGGAAGGAAAACACCTCCTCCCTTAGGGAGGCTGCTAGCTTGAGTGTGGCCCTGCCTGA
CTCCACAGGTCTTTCATGAAGATTGCCCCATAAGTCTGAGGAACAGGATGCCCTCAACTCCCTC
TACATAAAGGAGTCTGTTGGCCATGGGTGTTGTGAGTACCATTGCTCTGGGACTGGGGTCCTAC
AAGAAGGACCTCCATGGCCCAAGTGCTGTGGTTCTGACCCACACACCCTACCCCTGCTCTCTCT
CAGGATGGTGGTCCCAAAGCTGGTCGTGAAGCAGCCTTTGGCCCTCAACAGGGTCTTCCAACAC
AATTAAAGCCTTGATTTACCTTATGTGGCTGCAGTGTCCTGGTGCCTCATGTTTACTGCCTGGG
AGGAGGGGGAGCAGAGACAGAAGAGACCTCCGGCAGGACTTTGATTGCTCTCTTTAGTGTATCG
CATGGTGAACCGGCATAAACAGAGTTGACGAATCTTTCTAAA

hide sequence

RefSeq Acc Id:

XM_006251366 ⟹ XP_006251428

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	83,037,082 - 83,052,187 (-)	NCBI
mRatBN7.2	14	78,813,490 - 78,828,531 (-)	NCBI
Rnor_6.0	14	84,174,139 - 84,189,299 (-)	NCBI
Rnor_5.0	14	84,857,864 - 84,873,021 (-)	NCBI

Sequence:

show sequence

AGAACAGCTGACGACAGAGCTCCGTCACGTGACCACCACTGTTCCCTGCTCAGTTTCTTGTCCC
CGAGAGTCAGAGTAAGTACTTTCCAGGGACTCCCGTGAAGTGCACCAGCAGCGTGCTTCCGGGT
GTTGAAGGGACAATTAATCTGTGAGGTTGCCTCTTTCTAAGCAAGTGACAAGTTGCTGTCAGAC
AAGCCCTCAAGGCGGGTTCCAGGAGTCTCTCACCTCCCACCTGTGCCTGCCATGGAGCTCCTGA
AGGCGCTGCTACTCCTGTCTGGAGTCCTCGGGGCTCTTGCTGAATTCTGTGTAATACCAAAGAT
GGACGGCCAGCTGGTAGAGAAGCTGGGCCAGCGTCTCTTACCTTGGATGGATCGGCTTTCCTCA
GAGCAGTTGAACCCCAGCATCTACGTCGGCCTGCGGCTTTCCAGCATGCAGGCTGGGACCAAGG
AGAACCTCTACCTTCACAACCTCAAACTCCATTACCAGCAGTGCCTCCTGCGGTCCACCTCGAG
TGATGATAACAGTGGTTGCCAGACTAAGATTTCTGGGGGCAGCTTGGCCCTCTACCTGCTTGCT
CTCAGGGCCAACTGTGAGCTCCTGGGGAGCCGAAAGGGTGACAGGATGGTCTCACAGCTCAAGT
GGTTCTTGGAGGATGAGAAGAAGGCCATTGGGCACCATCATGAAGGCCACCCCCACACCAGCTA
TTACCAGTATGGCCTCAGTATCCTGGCCCTGTGCGTCCACCGGAAGCGGGTCCATGACAGTGTG
GTGGGCAAGCTCCTGTATGCTGTTGAACATGACTACTTTACCTACCAGGGCCACCTCTCTGTGG
ACACAGAAGCCATGGCCGGCTTGGCCTTCACCTGTTTGGAACGATTCAATTTCAACTCTGACCT
GAGACCACGGATCACCACGGCCATCGAGACAGTGCGAGAGAAGATCCTGAAGGCCCAGGCCCCT
GAGGGCTACTTTGGAAATATCTATAGCACTCCGCTGGCACTACAGATGCTAATGACCTCTCCTG
GGGTAGGGCTGGGCCCAGCTTGCCTCAAGGCAAGGAAATCCCTGCTGCTCAGCCTACAGGATGG
AGCCTTCCAGAATCCTATGATGATTTCCCAGCTGCTACCCGTCCTGAACCACAAGACCTACTTG
AATCTTATCTCCCCAGACTGCCAGGCACCCAGGGTCATGTTGGTGCCCGCCACTGAGGACCCTG
TCCACTTGTCAGAAGTCAGCGTCACGCTGAAGGTCTCCAGTGTCTTGCCACCATATGAACGAAC
AGTTTCCGTCTTTGCTGGGGCCTCCTTGGAAGATGTCCTGAAGAGGGCGCGAGACCTTGGAGAA
TTCACGTATGGGACCCAGGCCTCCTTGTCAGGTCCCTACCTGACATCCGTACTAGGGAAAGAAG
CTGGGGATCGAGAATACTGGCAGCTTCTCCGAGTCCCTGATACCCCTCTGCTACAAGGCATTGC
TGACTACAAACCCAAGAACGGGGAAACCATCGAATTGCGGCTAGTTAGATGGTAGCCCTAGGCT
CCCTCCTGATGTCTTCGGACCCTGCTGCCACCTCAAGTGCGCTTGGAACAATGTCCCCCAGATC
ACCTCAGCTAACTTCCCAAAGAGGACCTAAGCCACTGTCCACCTTAGAGCAGGAAGGAAAACAC
CTCCTCCCTTAGGGAGGCTGCTAGCTTGAGTGTGGCCCTGCCTGACTCCACAGGTCTTTCATGA
AGATTGCCCCATAAGTCTGAGGAACAGGATGCCCTCAACTCCCTCTACATAAAGGAGTCTGTTG
GCCATGGGTGTTGTGAGTACCATTGCTCTGGGACTGGGGTCCTACAAGAAGGACCTCCATGGCC
CAAGTGCTGTGGTTCTGACCCACACACCCTACCCCTGCTCTCTCTCAGGATGGTGGTCCCAAAG
CTGGTCGTGAAGCAGCCTTTGGCCCTCAACAGGGTCTTCCAACACAATTAAAGCCTTGATTTAC
CTTA

hide sequence

RefSeq Acc Id:

XM_006251367 ⟹ XP_006251429

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	83,037,082 - 83,052,095 (-)	NCBI
mRatBN7.2	14	78,813,490 - 78,828,492 (-)	NCBI
Rnor_6.0	14	84,174,139 - 84,189,297 (-)	NCBI
Rnor_5.0	14	84,857,864 - 84,873,021 (-)	NCBI

Sequence:

show sequence

AACAGCTGACGACAGAGCTCCGTCACGTGACCACCACTGTTCCCTGCTCAGTTTCTTGTCCCCG
AGAGTCAGAGTAAGTACTTTCCAGGGACTCCCGTGAAGTGCACCAGCGTGCTTCCGGGTGTTGA
AGGGACAATTAATCTGTGAGGTTGCCTCTTTCTAAGCAAGTGACAAGTTGCTGTCAGACAAGCC
CTCAAGGCGGGTTCCAGGAGTCTCTCACCTCCCACCTGTGCCTGCCATGGAGCTCCTGAAGGCG
CTGCTACTCCTGTCTGGAGTCCTCGGGGCTCTTGCTGAATTCTGTGTAATACCAAAGATGGACG
GCCAGCTGGTAGAGAAGCTGGGCCAGCGTCTCTTACCTTGGATGGATCGGCTTTCCTCAGAGCA
GTTGAACCCCAGCATCTACGTCGGCCTGCGGCTTTCCAGCATGCAGGCTGGGACCAAGGAGAAC
CTCTACCTTCACAACCTCAAACTCCATTACCAGCAGTGCCTCCTGCGGTCCACCTCGAGTGATG
ATAACAGTGGTTGCCAGACTAAGATTTCTGGGGGCAGCTTGGCCCTCTACCTGCTTGCTCTCAG
GGCCAACTGTGAGCTCCTGGGGAGCCGAAAGGGTGACAGGATGGTCTCACAGCTCAAGTGGTTC
TTGGAGGATGAGAAGAAGGCCATTGGGCACCATCATGAAGGCCACCCCCACACCAGCTATTACC
AGTATGGCCTCAGTATCCTGGCCCTGTGCGTCCACCGGAAGCGGGTCCATGACAGTGTGGTGGG
CAAGCTCCTGTATGCTGTTGAACATGACTACTTTACCTACCAGGGCCACCTCTCTGTGGACACA
GAAGCCATGGCCGGCTTGGCCTTCACCTGTTTGGAACGATTCAATTTCAACTCTGACCTGAGAC
CACGGATCACCACGGCCATCGAGACAGTGCGAGAGAAGATCCTGAAGGCCCAGGCCCCTGAGGG
CTACTTTGGAAATATCTATAGCACTCCGCTGGCACTACAGATGCTAATGACCTCTCCTGGGGTA
GGGCTGGGCCCAGCTTGCCTCAAGGCAAGGAAATCCCTGCTGCTCAGCCTACAGGATGGAGCCT
TCCAGAATCCTATGATGATTTCCCAGCTGCTACCCGTCCTGAACCACAAGACCTACTTGAATCT
TATCTCCCCAGACTGCCAGGCACCCAGGGTCATGTTGGTGCCCGCCACTGAGGACCCTGTCCAC
TTGTCAGAAGTCAGCGTCACGCTGAAGGTCTCCAGTGTCTTGCCACCATATGAACGAACAGTTT
CCGTCTTTGCTGGGGCCTCCTTGGAAGATGTCCTGAAGAGGGCGCGAGACCTTGGAGAATTCAC
GTATGGGACCCAGGCCTCCTTGTCAGGTCCCTACCTGACATCCGTACTAGGGAAAGAAGCTGGG
GATCGAGAATACTGGCAGCTTCTCCGAGTCCCTGATACCCCTCTGCTACAAGGCATTGCTGACT
ACAAACCCAAGAACGGGGAAACCATCGAATTGCGGCTAGTTAGATGGTAGCCCTAGGCTCCCTC
CTGATGTCTTCGGACCCTGCTGCCACCTCAAGTGCGCTTGGAACAATGTCCCCCAGATCACCTC
AGCTAACTTCCCAAAGAGGACCTAAGCCACTGTCCACCTTAGAGCAGGAAGGAAAACACCTCCT
CCCTTAGGGAGGCTGCTAGCTTGAGTGTGGCCCTGCCTGACTCCACAGGTCTTTCATGAAGATT
GCCCCATAAGTCTGAGGAACAGGATGCCCTCAACTCCCTCTACATAAAGGAGTCTGTTGGCCAT
GGGTGTTGTGAGTACCATTGCTCTGGGACTGGGGTCCTACAAGAAGGACCTCCATGGCCCAAGT
GCTGTGGTTCTGACCCACACACCCTACCCCTGCTCTCTCTCAGGATGGTGGTCCCAAAGCTGGT
CGTGAAGCAGCCTTTGGCCCTCAACAGGGTCTTCCAACACAATTAAAGCCTTGATTTACCTTA

hide sequence

RefSeq Acc Id:

XM_006251368 ⟹ XP_006251430

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	83,037,082 - 83,052,141 (-)	NCBI
mRatBN7.2	14	78,813,490 - 78,828,549 (-)	NCBI
Rnor_6.0	14	84,174,139 - 84,189,295 (-)	NCBI
Rnor_5.0	14	84,857,864 - 84,873,021 (-)	NCBI

Sequence:

show sequence

CAGCTGACGACAGAGCTCCGTCACGTGACCACCACTGTTCCCTGCTCAGTTTCTTGTCCCCGAG
AGTCAGAGTAAGTACTTTCCAGGGACTCCCGTGAAGTGCACCAGCAAGTGACAAGTTGCTGTCA
GACAAGCCCTCAAGGCGGGTTCCAGGAGTCTCTCACCTCCCACCTGTGCCTGCCATGGAGCTCC
TGAAGGCGCTGCTACTCCTGTCTGGAGTCCTCGGGGCTCTTGCTGAATTCTGTGTAATACCAAA
GATGGACGGCCAGCTGGTAGAGAAGCTGGGCCAGCGTCTCTTACCTTGGATGGATCGGCTTTCC
TCAGAGCAGTTGAACCCCAGCATCTACGTCGGCCTGCGGCTTTCCAGCATGCAGGCTGGGACCA
AGGAGAACCTCTACCTTCACAACCTCAAACTCCATTACCAGCAGTGCCTCCTGCGGTCCACCTC
GAGTGATGATAACAGTGGTTGCCAGACTAAGATTTCTGGGGGCAGCTTGGCCCTCTACCTGCTT
GCTCTCAGGGCCAACTGTGAGCTCCTGGGGAGCCGAAAGGGTGACAGGATGGTCTCACAGCTCA
AGTGGTTCTTGGAGGATGAGAAGAAGGCCATTGGGCACCATCATGAAGGCCACCCCCACACCAG
CTATTACCAGTATGGCCTCAGTATCCTGGCCCTGTGCGTCCACCGGAAGCGGGTCCATGACAGT
GTGGTGGGCAAGCTCCTGTATGCTGTTGAACATGACTACTTTACCTACCAGGGCCACCTCTCTG
TGGACACAGAAGCCATGGCCGGCTTGGCCTTCACCTGTTTGGAACGATTCAATTTCAACTCTGA
CCTGAGACCACGGATCACCACGGCCATCGAGACAGTGCGAGAGAAGATCCTGAAGGCCCAGGCC
CCTGAGGGCTACTTTGGAAATATCTATAGCACTCCGCTGGCACTACAGATGCTAATGACCTCTC
CTGGGGTAGGGCTGGGCCCAGCTTGCCTCAAGGCAAGGAAATCCCTGCTGCTCAGCCTACAGGA
TGGAGCCTTCCAGAATCCTATGATGATTTCCCAGCTGCTACCCGTCCTGAACCACAAGACCTAC
TTGAATCTTATCTCCCCAGACTGCCAGGCACCCAGGGTCATGTTGGTGCCCGCCACTGAGGACC
CTGTCCACTTGTCAGAAGTCAGCGTCACGCTGAAGGTCTCCAGTGTCTTGCCACCATATGAACG
AACAGTTTCCGTCTTTGCTGGGGCCTCCTTGGAAGATGTCCTGAAGAGGGCGCGAGACCTTGGA
GAATTCACGTATGGGACCCAGGCCTCCTTGTCAGGTCCCTACCTGACATCCGTACTAGGGAAAG
AAGCTGGGGATCGAGAATACTGGCAGCTTCTCCGAGTCCCTGATACCCCTCTGCTACAAGGCAT
TGCTGACTACAAACCCAAGAACGGGGAAACCATCGAATTGCGGCTAGTTAGATGGTAGCCCTAG
GCTCCCTCCTGATGTCTTCGGACCCTGCTGCCACCTCAAGTGCGCTTGGAACAATGTCCCCCAG
ATCACCTCAGCTAACTTCCCAAAGAGGACCTAAGCCACTGTCCACCTTAGAGCAGGAAGGAAAA
CACCTCCTCCCTTAGGGAGGCTGCTAGCTTGAGTGTGGCCCTGCCTGACTCCACAGGTCTTTCA
TGAAGATTGCCCCATAAGTCTGAGGAACAGGATGCCCTCAACTCCCTCTACATAAAGGAGTCTG
TTGGCCATGGGTGTTGTGAGTACCATTGCTCTGGGACTGGGGTCCTACAAGAAGGACCTCCATG
GCCCAAGTGCTGTGGTTCTGACCCACACACCCTACCCCTGCTCTCTCTCAGGATGGTGGTCCCA
AAGCTGGTCGTGAAGCAGCCTTTGGCCCTCAACAGGGTCTTCCAACACAATTAAAGCCTTGATT
TACCTTA

hide sequence

RefSeq Acc Id:

XM_006251370 ⟹ XP_006251432

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	83,037,082 - 83,052,101 (-)	NCBI
mRatBN7.2	14	78,813,490 - 78,828,510 (-)	NCBI
Rnor_6.0	14	84,174,139 - 84,189,290 (-)	NCBI
Rnor_5.0	14	84,857,864 - 84,873,021 (-)	NCBI

Sequence:

show sequence

GACGACAGAGCTCCGTCACGTGACCACCACTGTTCCCTGCTCAGTTTCTTGTCCCCGAGAGTCA
GAGTAAGTACTTTCCAGGGACTCCCGTGAAGTGCACCAGTGACAAGTTGCTGTCAGACAAGCCC
TCAAGGCGGGTTCCAGGAGTCTCTCACCTCCCACCTGTGCCTGCCATGGAGCTCCTGAAGGCGC
TGCTACTCCTGTCTGGAGTCCTCGGGGCTCTTGCTGAATTCTGTGTAATACCAAAGATGGACGG
CCAGCTGGTAGAGAAGCTGGGCCAGCGTCTCTTACCTTGGATGGATCGGCTTTCCTCAGAGCAG
TTGAACCCCAGCATCTACGTCGGCCTGCGGCTTTCCAGCATGCAGGCTGGGACCAAGGAGAACC
TCTACCTTCACAACCTCAAACTCCATTACCAGCAGTGCCTCCTGCGGTCCACCTCGAGTGATGA
TAACAGTGGTTGCCAGACTAAGATTTCTGGGGGCAGCTTGGCCCTCTACCTGCTTGCTCTCAGG
GCCAACTGTGAGCTCCTGGGGAGCCGAAAGGGTGACAGGATGGTCTCACAGCTCAAGTGGTTCT
TGGAGGATGAGAAGAAGGCCATTGGGCACCATCATGAAGGCCACCCCCACACCAGCTATTACCA
GTATGGCCTCAGTATCCTGGCCCTGTGCGTCCACCGGAAGCGGGTCCATGACAGTGTGGTGGGC
AAGCTCCTGTATGCTGTTGAACATGACTACTTTACCTACCAGGGCCACCTCTCTGTGGACACAG
AAGCCATGGCCGGCTTGGCCTTCACCTGTTTGGAACGATTCAATTTCAACTCTGACCTGAGACC
ACGGATCACCACGGCCATCGAGACAGTGCGAGAGAAGATCCTGAAGGCCCAGGCCCCTGAGGGC
TACTTTGGAAATATCTATAGCACTCCGCTGGCACTACAGATGCTAATGACCTCTCCTGGGGTAG
GGCTGGGCCCAGCTTGCCTCAAGGCAAGGAAATCCCTGCTGCTCAGCCTACAGGATGGAGCCTT
CCAGAATCCTATGATGATTTCCCAGCTGCTACCCGTCCTGAACCACAAGACCTACTTGAATCTT
ATCTCCCCAGACTGCCAGGCACCCAGGGTCATGTTGGTGCCCGCCACTGAGGACCCTGTCCACT
TGTCAGAAGTCAGCGTCACGCTGAAGGTCTCCAGTGTCTTGCCACCATATGAACGAACAGTTTC
CGTCTTTGCTGGGGCCTCCTTGGAAGATGTCCTGAAGAGGGCGCGAGACCTTGGAGAATTCACG
TATGGGACCCAGGCCTCCTTGTCAGGTCCCTACCTGACATCCGTACTAGGGAAAGAAGCTGGGG
ATCGAGAATACTGGCAGCTTCTCCGAGTCCCTGATACCCCTCTGCTACAAGGCATTGCTGACTA
CAAACCCAAGAACGGGGAAACCATCGAATTGCGGCTAGTTAGATGGTAGCCCTAGGCTCCCTCC
TGATGTCTTCGGACCCTGCTGCCACCTCAAGTGCGCTTGGAACAATGTCCCCCAGATCACCTCA
GCTAACTTCCCAAAGAGGACCTAAGCCACTGTCCACCTTAGAGCAGGAAGGAAAACACCTCCTC
CCTTAGGGAGGCTGCTAGCTTGAGTGTGGCCCTGCCTGACTCCACAGGTCTTTCATGAAGATTG
CCCCATAAGTCTGAGGAACAGGATGCCCTCAACTCCCTCTACATAAAGGAGTCTGTTGGCCATG
GGTGTTGTGAGTACCATTGCTCTGGGACTGGGGTCCTACAAGAAGGACCTCCATGGCCCAAGTG
CTGTGGTTCTGACCCACACACCCTACCCCTGCTCTCTCTCAGGATGGTGGTCCCAAAGCTGGTC
GTGAAGCAGCCTTTGGCCCTCAACAGGGTCTTCCAACACAATTAAAGCCTTGATTTACCTTA

hide sequence

RefSeq Acc Id:

XM_017599370 ⟹ XP_017454859

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	83,037,082 - 83,052,093 (-)	NCBI
mRatBN7.2	14	78,813,490 - 78,828,448 (-)	NCBI
Rnor_6.0	14	84,174,139 - 84,189,288 (-)	NCBI

Sequence:

show sequence

CGACAGAGCTCCGTCACGTGACCACCACTGTTCCCTGCTCAGTTTCTTGTCCCCGAGAGTCAGA
CAGCGTGCTTCCGGGTGTTGAAGGGACAATTAATCTGTGAGGTTGCCTCTTTCTAAGCAAGTGA
CAAGTTGCTGTCAGACAAGCCCTCAAGGCGGGTTCCAGGAGTCTCTCACCTCCCACCTGTGCCT
GCCATGGAGCTCCTGAAGGCGCTGCTACTCCTGTCTGGAGTCCTCGGGGCTCTTGCTGAATTCT
GTGTAATACCAAAGATGGACGGCCAGCTGGTAGAGAAGCTGGGCCAGCGTCTCTTACCTTGGAT
GGATCGGCTTTCCTCAGAGCAGTTGAACCCCAGCATCTACGTCGGCCTGCGGCTTTCCAGCATG
CAGGCTGGGACCAAGGAGAACCTCTACCTTCACAACCTCAAACTCCATTACCAGCAGTGCCTCC
TGCGGTCCACCTCGAGTGATGATAACAGTGGTTGCCAGACTAAGATTTCTGGGGGCAGCTTGGC
CCTCTACCTGCTTGCTCTCAGGGCCAACTGTGAGCTCCTGGGGAGCCGAAAGGGTGACAGGATG
GTCTCACAGCTCAAGTGGTTCTTGGAGGATGAGAAGAAGGCCATTGGGCACCATCATGAAGGCC
ACCCCCACACCAGCTATTACCAGTATGGCCTCAGTATCCTGGCCCTGTGCGTCCACCGGAAGCG
GGTCCATGACAGTGTGGTGGGCAAGCTCCTGTATGCTGTTGAACATGACTACTTTACCTACCAG
GGCCACCTCTCTGTGGACACAGAAGCCATGGCCGGCTTGGCCTTCACCTGTTTGGAACGATTCA
ATTTCAACTCTGACCTGAGACCACGGATCACCACGGCCATCGAGACAGTGCGAGAGAAGATCCT
GAAGGCCCAGGCCCCTGAGGGCTACTTTGGAAATATCTATAGCACTCCGCTGGCACTACAGATG
CTAATGACCTCTCCTGGGGTAGGGCTGGGCCCAGCTTGCCTCAAGGCAAGGAAATCCCTGCTGC
TCAGCCTACAGGATGGAGCCTTCCAGAATCCTATGATGATTTCCCAGCTGCTACCCGTCCTGAA
CCACAAGACCTACTTGAATCTTATCTCCCCAGACTGCCAGGCACCCAGGGTCATGTTGGTGCCC
GCCACTGAGGACCCTGTCCACTTGTCAGAAGTCAGCGTCACGCTGAAGGTCTCCAGTGTCTTGC
CACCATATGAACGAACAGTTTCCGTCTTTGCTGGGGCCTCCTTGGAAGATGTCCTGAAGAGGGC
GCGAGACCTTGGAGAATTCACGTATGGGACCCAGGCCTCCTTGTCAGGTCCCTACCTGACATCC
GTACTAGGGAAAGAAGCTGGGGATCGAGAATACTGGCAGCTTCTCCGAGTCCCTGATACCCCTC
TGCTACAAGGCATTGCTGACTACAAACCCAAGAACGGGGAAACCATCGAATTGCGGCTAGTTAG
ATGGTAGCCCTAGGCTCCCTCCTGATGTCTTCGGACCCTGCTGCCACCTCAAGTGCGCTTGGAA
CAATGTCCCCCAGATCACCTCAGCTAACTTCCCAAAGAGGACCTAAGCCACTGTCCACCTTAGA
GCAGGAAGGAAAACACCTCCTCCCTTAGGGAGGCTGCTAGCTTGAGTGTGGCCCTGCCTGACTC
CACAGGTCTTTCATGAAGATTGCCCCATAAGTCTGAGGAACAGGATGCCCTCAACTCCCTCTAC
ATAAAGGAGTCTGTTGGCCATGGGTGTTGTGAGTACCATTGCTCTGGGACTGGGGTCCTACAAG
AAGGACCTCCATGGCCCAAGTGCTGTGGTTCTGACCCACACACCCTACCCCTGCTCTCTCTCAG
GATGGTGGTCCCAAAGCTGGTCGTGAAGCAGCCTTTGGCCCTCAACAGGGTCTTCCAACACAAT
TAAAGCCTTGATTTACCTTA

hide sequence

Protein Sequences


Protein RefSeqs	NP_071979	(Get FASTA)	NCBI Sequence Viewer
	XP_006251428	(Get FASTA)	NCBI Sequence Viewer
	XP_006251429	(Get FASTA)	NCBI Sequence Viewer
	XP_006251430	(Get FASTA)	NCBI Sequence Viewer
	XP_006251432	(Get FASTA)	NCBI Sequence Viewer
	XP_017454859	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD55672	(Get FASTA)	NCBI Sequence Viewer
	EDM00197	(Get FASTA)	NCBI Sequence Viewer
	EDM00198	(Get FASTA)	NCBI Sequence Viewer
	EDM00199	(Get FASTA)	NCBI Sequence Viewer
	EDM00200	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000005934
GenBank Protein	Q9R0D6	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_071979 ⟸ NM_022534
- Peptide Label:	precursor
- UniProtKB:	Q9R0D6 (UniProtKB/Swiss-Prot), G3V6K1 (UniProtKB/TrEMBL), A6IKD4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MELLKALLLLSGVLGALAEFCVIPKMDGQLVEKLGQRLLPWMDRLSSEQLNPSIYVGLRLSSMQ AGTKENLYLHNLKLHYQQCLLRSTSSDDNSGCQTKISGGSLALYLLALRANCELLGSRKGDRMV SQLKWFLEDEKKAIGHHHEGHPHTSYYQYGLSILALCVHRKRVHDSVVGKLLYAVEHDYFTYQG HLSVDTEAMAGLAFTCLERFNFNSDLRPRITTAIETVREKILKAQAPEGYFGNIYSTPLALQML MTSPGVGLGPACLKARKSLLLSLQDGAFQNPMMISQLLPVLNHKTYLNLISPDCQAPRVMLVPA TEDPVHLSEVSVTLKVSSVLPPYERTVSVFAGASLEDVLKRARDLGEFTYGTQASLSGPYLTSV LGKEAGDREYWQLLRVPDTPLLQGIADYKPKNGETIELRLVRW hide sequence

RefSeq Acc Id:	XP_006251428 ⟸ XM_006251366
- Peptide Label:	isoform X1
- UniProtKB:	Q9R0D6 (UniProtKB/Swiss-Prot), G3V6K1 (UniProtKB/TrEMBL), A6IKD4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MELLKALLLLSGVLGALAEFCVIPKMDGQLVEKLGQRLLPWMDRLSSEQLNPSIYVGLRLSSMQ AGTKENLYLHNLKLHYQQCLLRSTSSDDNSGCQTKISGGSLALYLLALRANCELLGSRKGDRMV SQLKWFLEDEKKAIGHHHEGHPHTSYYQYGLSILALCVHRKRVHDSVVGKLLYAVEHDYFTYQG HLSVDTEAMAGLAFTCLERFNFNSDLRPRITTAIETVREKILKAQAPEGYFGNIYSTPLALQML MTSPGVGLGPACLKARKSLLLSLQDGAFQNPMMISQLLPVLNHKTYLNLISPDCQAPRVMLVPA TEDPVHLSEVSVTLKVSSVLPPYERTVSVFAGASLEDVLKRARDLGEFTYGTQASLSGPYLTSV LGKEAGDREYWQLLRVPDTPLLQGIADYKPKNGETIELRLVRW hide sequence

RefSeq Acc Id:	XP_006251430 ⟸ XM_006251368
- Peptide Label:	isoform X1
- UniProtKB:	Q9R0D6 (UniProtKB/Swiss-Prot), G3V6K1 (UniProtKB/TrEMBL), A6IKD4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MELLKALLLLSGVLGALAEFCVIPKMDGQLVEKLGQRLLPWMDRLSSEQLNPSIYVGLRLSSMQ AGTKENLYLHNLKLHYQQCLLRSTSSDDNSGCQTKISGGSLALYLLALRANCELLGSRKGDRMV SQLKWFLEDEKKAIGHHHEGHPHTSYYQYGLSILALCVHRKRVHDSVVGKLLYAVEHDYFTYQG HLSVDTEAMAGLAFTCLERFNFNSDLRPRITTAIETVREKILKAQAPEGYFGNIYSTPLALQML MTSPGVGLGPACLKARKSLLLSLQDGAFQNPMMISQLLPVLNHKTYLNLISPDCQAPRVMLVPA TEDPVHLSEVSVTLKVSSVLPPYERTVSVFAGASLEDVLKRARDLGEFTYGTQASLSGPYLTSV LGKEAGDREYWQLLRVPDTPLLQGIADYKPKNGETIELRLVRW hide sequence

RefSeq Acc Id:	XP_006251429 ⟸ XM_006251367
- Peptide Label:	isoform X1
- UniProtKB:	Q9R0D6 (UniProtKB/Swiss-Prot), G3V6K1 (UniProtKB/TrEMBL), A6IKD4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MELLKALLLLSGVLGALAEFCVIPKMDGQLVEKLGQRLLPWMDRLSSEQLNPSIYVGLRLSSMQ AGTKENLYLHNLKLHYQQCLLRSTSSDDNSGCQTKISGGSLALYLLALRANCELLGSRKGDRMV SQLKWFLEDEKKAIGHHHEGHPHTSYYQYGLSILALCVHRKRVHDSVVGKLLYAVEHDYFTYQG HLSVDTEAMAGLAFTCLERFNFNSDLRPRITTAIETVREKILKAQAPEGYFGNIYSTPLALQML MTSPGVGLGPACLKARKSLLLSLQDGAFQNPMMISQLLPVLNHKTYLNLISPDCQAPRVMLVPA TEDPVHLSEVSVTLKVSSVLPPYERTVSVFAGASLEDVLKRARDLGEFTYGTQASLSGPYLTSV LGKEAGDREYWQLLRVPDTPLLQGIADYKPKNGETIELRLVRW hide sequence

RefSeq Acc Id:	XP_006251432 ⟸ XM_006251370
- Peptide Label:	isoform X1
- UniProtKB:	Q9R0D6 (UniProtKB/Swiss-Prot), G3V6K1 (UniProtKB/TrEMBL), A6IKD4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MELLKALLLLSGVLGALAEFCVIPKMDGQLVEKLGQRLLPWMDRLSSEQLNPSIYVGLRLSSMQ AGTKENLYLHNLKLHYQQCLLRSTSSDDNSGCQTKISGGSLALYLLALRANCELLGSRKGDRMV SQLKWFLEDEKKAIGHHHEGHPHTSYYQYGLSILALCVHRKRVHDSVVGKLLYAVEHDYFTYQG HLSVDTEAMAGLAFTCLERFNFNSDLRPRITTAIETVREKILKAQAPEGYFGNIYSTPLALQML MTSPGVGLGPACLKARKSLLLSLQDGAFQNPMMISQLLPVLNHKTYLNLISPDCQAPRVMLVPA TEDPVHLSEVSVTLKVSSVLPPYERTVSVFAGASLEDVLKRARDLGEFTYGTQASLSGPYLTSV LGKEAGDREYWQLLRVPDTPLLQGIADYKPKNGETIELRLVRW hide sequence

RefSeq Acc Id:	XP_017454859 ⟸ XM_017599370
- Peptide Label:	isoform X1
- UniProtKB:	Q9R0D6 (UniProtKB/Swiss-Prot), G3V6K1 (UniProtKB/TrEMBL), A6IKD4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MELLKALLLLSGVLGALAEFCVIPKMDGQLVEKLGQRLLPWMDRLSSEQLNPSIYVGLRLSSMQ AGTKENLYLHNLKLHYQQCLLRSTSSDDNSGCQTKISGGSLALYLLALRANCELLGSRKGDRMV SQLKWFLEDEKKAIGHHHEGHPHTSYYQYGLSILALCVHRKRVHDSVVGKLLYAVEHDYFTYQG HLSVDTEAMAGLAFTCLERFNFNSDLRPRITTAIETVREKILKAQAPEGYFGNIYSTPLALQML MTSPGVGLGPACLKARKSLLLSLQDGAFQNPMMISQLLPVLNHKTYLNLISPDCQAPRVMLVPA TEDPVHLSEVSVTLKVSSVLPPYERTVSVFAGASLEDVLKRARDLGEFTYGTQASLSGPYLTSV LGKEAGDREYWQLLRVPDTPLLQGIADYKPKNGETIELRLVRW hide sequence

Ensembl Acc Id:

ENSRNOP00000005934 ⟸ ENSRNOT00000005934

Ensembl Acc Id:

ENSRNOP00000077856 ⟸ ENSRNOT00000093962

Protein Domains

Transcobalamin-like C-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9R0D6-F1-model_v2	AlphaFold	Q9R0D6	1-427	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699434

Promoter ID:

EPDNEW_R9958

Type:

initiation region

Name:

Tcn2_1

Description:

transcobalamin 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	14	84,189,248 - 84,189,308	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620681	AgrOrtholog
BioCyc Gene	G2FUF-15207	BioCyc
Ensembl Genes	ENSRNOG00000004280	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000005934	ENTREZGENE
Gene3D-CATH	1.50.10.20	UniProtKB/Swiss-Prot
	2.170.130.30	UniProtKB/Swiss-Prot
InterPro	Cbl-bd_prot	UniProtKB/Swiss-Prot
	Cobalamin_Transport	UniProtKB/Swiss-Prot
	DUF4430	UniProtKB/Swiss-Prot
NCBI Gene	64365	ENTREZGENE
PANTHER	TRANSCOBALAMIN-1/GASTRIC INTRINSIC FACTOR	UniProtKB/Swiss-Prot
	TRANSCOBALAMIN-2	UniProtKB/Swiss-Prot
Pfam	Cobalamin_bind	UniProtKB/Swiss-Prot
	DUF4430	UniProtKB/Swiss-Prot
PhenoGen	Tcn2	PhenoGen
PROSITE	COBALAMIN_BINDING	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000004280	RatGTEx
UniProt	A0A8I5YCJ2_RAT	UniProtKB/TrEMBL
	A6IKD3_RAT	UniProtKB/TrEMBL
	A6IKD4	ENTREZGENE, UniProtKB/TrEMBL
	A6IKD6_RAT	UniProtKB/TrEMBL
	G3V6K1	ENTREZGENE, UniProtKB/TrEMBL
	Q9R0D6	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-04-22	Tcn2	transcobalamin 2	Tcn2p	transcobalamin II precursor	Symbol and Name updated to reflect Human and Mouse nomenclature	625702	APPROVED
2002-08-07	Tcn2p	transcobalamin II precursor			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_protein	mature product is a nonglycoprotein secretory protein of molecular mass 43 kDa	724784

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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