Ralgapa1 (Ral GTPase activating protein catalytic subunit alpha 1) - Rat Genome Database

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Gene: Ralgapa1 (Ral GTPase activating protein catalytic subunit alpha 1) Rattus norvegicus
Analyze
Symbol: Ralgapa1
Name: Ral GTPase activating protein catalytic subunit alpha 1
RGD ID: 620642
Description: Predicted to enable GTPase activator activity and protein heterodimerization activity. Predicted to be involved in activation of GTPase activity. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Orthologous to human RALGAPA1 (Ral GTPase activating protein catalytic subunit alpha 1); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GAP-related-interacting partner to E12; Garnl1; GRIPE; GTPase activating RANGAP domain-like 1; GTPase activating Rap/RanGAP domain-like 1; GTPase-activating RapGAP domain-like 1; p240; Ral GTPase activating protein catalytic alpha subunit 1; Ral GTPase activating protein, alpha subunit 1 (catalytic); ral GTPase-activating protein alpha subunit 1; ral GTPase-activating protein subunit alpha-1; tuberin-like protein 1; tulip 1; Tulip1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8678,712,554 - 78,987,486 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl678,701,832 - 78,987,486 (-)EnsemblGRCr8
mRatBN7.2672,977,432 - 73,252,378 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl672,977,432 - 73,252,378 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx673,399,057 - 73,673,165 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0673,705,427 - 73,979,553 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0673,132,937 - 73,407,056 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0676,386,971 - 76,661,530 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl676,396,784 - 76,608,864 (-)Ensemblrn6Rnor6.0
Rnor_5.0685,920,793 - 86,193,578 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4675,849,629 - 76,163,553 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera671,819,235 - 72,085,407 (-)NCBICelera
RGSC_v3.1675,853,593 - 76,049,363 (-)NCBI
Cytogenetic Map6q23NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,6-dinitrotoluene  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
6-propyl-2-thiouracil  (EXP)
Aflatoxin B2 alpha  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (ISO)
caffeine  (ISO)
chromium atom  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dimethyl sulfoxide  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
FR900359  (ISO)
gamma-hexachlorocyclohexane  (EXP)
genistein  (EXP)
gentamycin  (EXP)
glyphosate  (ISO)
hydrogen peroxide  (ISO)
lead diacetate  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methamphetamine  (ISO)
methapyrilene  (EXP)
methimazole  (EXP)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
nicotinic acid  (ISO)
oxaliplatin  (EXP)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (EXP)
propiconazole  (EXP)
resveratrol  (ISO)
rotenone  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
tamoxifen  (ISO)
thioacetamide  (EXP)
topotecan  (EXP)
triphenyl phosphate  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA,ISO,ISS)
nucleus  (IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Cloning and characterization of GRIPE, a novel interacting partner of the transcription factor E12 in developing mouse forebrain. Heng JI and Tan SS, J Biol Chem 2002 Nov 8;277(45):43152-9.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:12477932   PMID:19520869  


Genomics

Comparative Map Data
Ralgapa1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8678,712,554 - 78,987,486 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl678,701,832 - 78,987,486 (-)EnsemblGRCr8
mRatBN7.2672,977,432 - 73,252,378 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl672,977,432 - 73,252,378 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx673,399,057 - 73,673,165 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0673,705,427 - 73,979,553 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0673,132,937 - 73,407,056 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0676,386,971 - 76,661,530 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl676,396,784 - 76,608,864 (-)Ensemblrn6Rnor6.0
Rnor_5.0685,920,793 - 86,193,578 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4675,849,629 - 76,163,553 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera671,819,235 - 72,085,407 (-)NCBICelera
RGSC_v3.1675,853,593 - 76,049,363 (-)NCBI
Cytogenetic Map6q23NCBI
RALGAPA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381435,538,356 - 35,809,295 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1435,538,352 - 35,809,304 (-)Ensemblhg38GRCh38
GRCh371436,007,562 - 36,278,501 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361435,077,309 - 35,348,183 (-)NCBIBuild 36Build 36hg18NCBI36
Celera1415,871,418 - 16,142,289 (-)NCBICelera
Cytogenetic Map14q13.2NCBI
HuRef1416,121,448 - 16,392,248 (-)NCBIHuRef
CHM1_11436,007,239 - 36,278,471 (-)NCBICHM1_1
T2T-CHM13v2.01429,726,082 - 29,997,030 (-)NCBIT2T-CHM13v2.0
Ralgapa1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391255,649,673 - 55,868,522 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1255,649,681 - 55,867,952 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381255,602,888 - 55,821,574 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1255,602,896 - 55,821,167 (-)Ensemblmm10GRCm38
MGSCv371256,703,886 - 56,922,154 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361256,521,029 - 56,739,297 (-)NCBIMGSCv36mm8
Celera1256,752,528 - 56,970,531 (-)NCBICelera
Cytogenetic Map12C1NCBI
cM Map1224.06NCBI
Ralgapa1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540925,337,699 - 25,583,657 (+)Ensembl
ChiLan1.0NW_00495540925,336,503 - 25,582,881 (+)NCBIChiLan1.0ChiLan1.0
RALGAPA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21536,852,776 - 37,123,524 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11436,069,279 - 36,340,001 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01416,292,189 - 16,562,880 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11434,472,884 - 34,743,430 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1434,472,880 - 34,743,430 (-)EnsemblpanPan2panpan1.1
RALGAPA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1814,221,516 - 14,463,481 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl814,222,749 - 14,462,998 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha814,017,673 - 14,259,618 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0814,327,816 - 14,570,610 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl814,327,816 - 14,570,547 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1814,028,892 - 14,271,002 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0814,094,489 - 14,336,412 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0814,384,204 - 14,626,322 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ralgapa1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864046,143,552 - 46,361,013 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364949,659,285 - 9,866,408 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364949,649,444 - 9,866,942 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RALGAPA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl764,141,014 - 64,372,694 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1764,140,977 - 64,372,683 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2769,115,446 - 69,174,647 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RALGAPA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12412,344,951 - 12,615,669 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2412,344,934 - 12,615,622 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660531,309,431 - 1,586,599 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ralgapa1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248381,040,525 - 1,258,151 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248381,040,108 - 1,269,000 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ralgapa1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1768,844,343 - 69,200,969 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ralgapa1
2616 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:328
Count of miRNA genes:189
Interacting mature miRNAs:231
Transcripts:ENSRNOT00000010824, ENSRNOT00000065230
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)64451097489510974Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)671278722116278722Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)664367996109367996Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)66345744194939581Rat
4889933Bss88Bone structure and strength QTL 883.8tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)65368492198684921Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)64095756485957564Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)64604735391047353Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)64515378690153786Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6186868070Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)66303731995934232Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63902865986867923Rat
5684963Bss99Bone structure and strength QTL 993.1tibia area (VT:1000281)tibia area measurement (CMO:0001382)65368492198684921Rat
5684992Bmd83Bone mineral density QTL 824.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)65368492198684921Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)678204640123204640Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)676937178121937178Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)64016318385163183Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)66345744194939581Rat

Markers in Region
AU047282  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2673,083,877 - 73,084,032 (+)MAPPERmRatBN7.2
Rnor_6.0676,493,032 - 76,493,188NCBIRnor6.0
Rnor_5.0686,025,765 - 86,025,921UniSTSRnor5.0
RGSC_v3.4675,959,706 - 75,959,862UniSTSRGSC3.4
Celera671,923,229 - 71,923,385UniSTS
Cytogenetic Map6q23UniSTS
AI563624  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2672,977,588 - 72,977,736 (+)MAPPERmRatBN7.2
Rnor_6.0676,387,128 - 76,387,275NCBIRnor6.0
Rnor_5.0685,920,946 - 85,921,093UniSTSRnor5.0
RGSC_v3.4675,849,782 - 75,849,929UniSTSRGSC3.4
Celera671,819,392 - 71,819,539UniSTS
Cytogenetic Map6q23UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000010824   ⟹   ENSRNOP00000010824
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl678,722,347 - 78,933,353 (-)Ensembl
mRatBN7.2 Ensembl672,986,789 - 73,198,245 (-)Ensembl
Rnor_6.0 Ensembl676,396,784 - 76,608,864 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000065230   ⟹   ENSRNOP00000059440
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl678,715,365 - 78,987,486 (-)Ensembl
mRatBN7.2 Ensembl673,020,311 - 73,252,378 (-)Ensembl
Rnor_6.0 Ensembl676,455,334 - 76,552,559 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000083857   ⟹   ENSRNOP00000073377
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl678,712,554 - 78,987,486 (-)Ensembl
mRatBN7.2 Ensembl672,977,432 - 73,252,378 (-)Ensembl
Rnor_6.0 Ensembl676,430,644 - 76,535,517 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100461   ⟹   ENSRNOP00000077870
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl678,712,554 - 78,987,486 (-)Ensembl
mRatBN7.2 Ensembl672,977,432 - 73,252,378 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107390   ⟹   ENSRNOP00000090394
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl678,712,554 - 78,987,486 (-)Ensembl
mRatBN7.2 Ensembl672,977,432 - 73,252,378 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115007   ⟹   ENSRNOP00000085629
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl678,713,718 - 78,987,486 (-)Ensembl
mRatBN7.2 Ensembl672,978,228 - 73,252,378 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000135549   ⟹   ENSRNOP00000112734
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl678,755,417 - 78,987,486 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000137071   ⟹   ENSRNOP00000100959
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl678,701,832 - 78,987,486 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000155190   ⟹   ENSRNOP00000103346
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl678,712,554 - 78,894,330 (-)Ensembl
RefSeq Acc Id: NM_020083   ⟹   NP_064468
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8678,712,554 - 78,987,486 (-)NCBI
mRatBN7.2672,977,432 - 73,252,378 (-)NCBI
Rnor_6.0676,386,971 - 76,661,530 (-)NCBI
Rnor_5.0685,920,793 - 86,193,578 (-)NCBI
Celera671,819,235 - 72,085,407 (-)NCBI
Sequence:
RefSeq Acc Id: NP_064468   ⟸   NM_020083
- UniProtKB: O55008 (UniProtKB/Swiss-Prot),   O55007 (UniProtKB/Swiss-Prot),   F1LSW3 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000059440   ⟸   ENSRNOT00000065230
Ensembl Acc Id: ENSRNOP00000010824   ⟸   ENSRNOT00000010824
Ensembl Acc Id: ENSRNOP00000073377   ⟸   ENSRNOT00000083857
Ensembl Acc Id: ENSRNOP00000085629   ⟸   ENSRNOT00000115007
Ensembl Acc Id: ENSRNOP00000090394   ⟸   ENSRNOT00000107390
Ensembl Acc Id: ENSRNOP00000077870   ⟸   ENSRNOT00000100461
Ensembl Acc Id: ENSRNOP00000100959   ⟸   ENSRNOT00000137071
Ensembl Acc Id: ENSRNOP00000103346   ⟸   ENSRNOT00000155190
Ensembl Acc Id: ENSRNOP00000112734   ⟸   ENSRNOT00000135549
Protein Domains
Rap-GAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O55007-F1-model_v2 AlphaFold O55007 1-2035 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694611
Promoter ID:EPDNEW_R5133
Type:single initiation site
Name:Ralgapa1_1
Description:Ral GTPase activating protein catalytic alpha subunit 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0676,552,587 - 76,552,647EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620642 AgrOrtholog
BioCyc Gene G2FUF-37483 BioCyc
Ensembl Genes ENSRNOG00000046256 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000065230.5 UniProtKB/Swiss-Prot
  ENSRNOT00000083857 ENTREZGENE
Gene3D-CATH 3.40.50.11210 UniProtKB/Swiss-Prot
InterPro ARM-type_fold UniProtKB/Swiss-Prot
  Rap/Ran-GAP_sf UniProtKB/Swiss-Prot
  Rap_GAP_dom UniProtKB/Swiss-Prot
  RGPA/RALGAPB_N UniProtKB/Swiss-Prot
  Tuberin/Ral-act_asu UniProtKB/Swiss-Prot
KEGG Report rno:56785 UniProtKB/Swiss-Prot
NCBI Gene 56785 ENTREZGENE
PANTHER PTHR10063 UniProtKB/Swiss-Prot
  RAL GTPASE-ACTIVATING PROTEIN SUBUNIT ALPHA-1 UniProtKB/Swiss-Prot
Pfam RALGAPB_N UniProtKB/Swiss-Prot
  Rap_GAP UniProtKB/Swiss-Prot
PhenoGen Ralgapa1 PhenoGen
PROSITE RAPGAP UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000046256 RatGTEx
Superfamily-SCOP SSF111347 UniProtKB/Swiss-Prot
  SSF48371 UniProtKB/Swiss-Prot
UniProt A0A0A0MY46_RAT UniProtKB/TrEMBL
  A0A140TAA3_RAT UniProtKB/TrEMBL
  A0A8I5Y6U1_RAT UniProtKB/TrEMBL
  A0A8I6A9F7_RAT UniProtKB/TrEMBL
  A0A8I6GE30_RAT UniProtKB/TrEMBL
  A0A8L2R757_RAT UniProtKB/TrEMBL
  A0ABK0L2W6_RAT UniProtKB/TrEMBL
  A0ABK0LDQ7_RAT UniProtKB/TrEMBL
  A0ABK0M6X6_RAT UniProtKB/TrEMBL
  F1LSW3 ENTREZGENE
  O55007 ENTREZGENE
  O55008 ENTREZGENE
  RGPA1_RAT UniProtKB/Swiss-Prot
UniProt Secondary F1LSW3 UniProtKB/Swiss-Prot
  O55008 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-12-06 Ralgapa1  Ral GTPase activating protein catalytic subunit alpha 1  Ralgapa1  Ral GTPase activating protein catalytic alpha subunit 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-03 Ralgapa1  Ral GTPase activating protein catalytic alpha subunit 1  Ralgapa1  Ral GTPase activating protein, alpha subunit 1 (catalytic)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-08-02 Ralgapa1  Ral GTPase activating protein, alpha subunit 1 (catalytic)  Garnl1  GTPase activating Rap/RanGAP domain-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-24 Garnl1  GTPase activating Rap/RanGAP domain-like 1  Garnl1  GTPase activating RANGAP domain-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Garnl1  GTPase activating RANGAP domain-like 1  Tulip1  tuberin-like protein 1  Symbol and Name updated 1299863 APPROVED
2002-08-07 Tulip1  tuberin-like protein 1      Symbol and Name status set to provisional 70820 PROVISIONAL