Zp3 (zona pellucida glycoprotein 3) - Rat Genome Database

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Gene: Zp3 (zona pellucida glycoprotein 3) Rattus norvegicus
Analyze
Symbol: Zp3
Name: zona pellucida glycoprotein 3
RGD ID: 620606
Description: Predicted to enable several functions, including acrosin binding activity; identical protein binding activity; and receptor ligand activity. Predicted to be a structural constituent of egg coat. Predicted to be involved in several processes, including oogenesis; positive regulation of immune response; and regulation of gene expression. Predicted to be located in several cellular components, including collagen-containing extracellular matrix; egg coat; and extracellular space. Predicted to be active in extracellular matrix. Orthologous to human ZP3 (zona pellucida glycoprotein 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: zona pellucida glycoprotein 3 (sperm receptor); zona pellucida glycoprotein ZP3; zona pellucida protein C; zona pellucida sperm-binding protein 3; Zp-3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81226,327,161 - 26,334,126 (-)NCBIGRCr8
mRatBN7.21220,690,547 - 20,697,513 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1220,690,547 - 20,697,513 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1221,831,035 - 21,838,010 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01222,443,745 - 22,450,720 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01221,508,864 - 21,516,408 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01223,735,225 - 23,752,734 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1223,735,223 - 23,742,190 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01225,733,873 - 25,740,838 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41221,805,746 - 21,812,711 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11221,792,837 - 21,799,583 (-)NCBI
Celera1222,453,873 - 22,460,838 (-)NCBICelera
Cytogenetic Map12q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Zp3RatChromosome 7q11.23 Deletion Syndrome, Distal, 1.2-MB  ISOZP3 (Homo sapiens)8554872ClinVar Annotator: match by term: DISTAL CHROMOSOME 7q11.23 DELETION SYNDROMEClinVar 
Zp3RatOocyte Maturation Defect 3  ISOZP3 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 more ...
Zp3Ratpleomorphic xanthoastrocytoma  ISOZP3 (Homo sapiens)8554872ClinVar Annotator: match by term: Pleomorphic xanthoastrocytomaClinVarPMID:28299358
Object Symbol
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Original Reference(s)
Zp3RatOocyte Maturation Defect 3  ISOZP3 (Homo sapiens)7240710 OMIM 

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Original Reference(s)
Zp3Rat17alpha-ethynylestradiol multiple interactionsISOZp3 (Mus musculus)6480464[Ibuprofen co-treated with hydroxyibuprofen co-treated with Diclofenac co-treated with Ethinyl Estradiol] results in decreased expression of ZP3 mRNACTDPMID:37844793
Zp3Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOZP3 (Homo sapiens)6480464[Tetrachlorodibenzodioxin co-treated with 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide] results in increased expression of ZP3 mRNACTDPMID:29704546
Zp3Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of ZP3 mRNACTDPMID:33387578
Zp3Rat5-azacytidine increases expressionISOZP3 (Homo sapiens)6480464Azacitidine results in increased expression of ZP3 mRNACTDPMID:20823114
Zp3Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of ZP3 mRNACTDPMID:22504374
Zp3Rataflatoxin B1 increases expressionISOZP3 (Homo sapiens)6480464Aflatoxin B1 results in increased expression of ZP3 mRNACTDPMID:21641981 and PMID:22100608
Zp3Rataflatoxin B1 decreases methylationISOZP3 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of ZP3 promoterCTDPMID:30157460
Zp3Ratall-trans-retinoic acid decreases expressionISOZP3 (Homo sapiens)6480464Tretinoin results in decreased expression of ZP3 mRNACTDPMID:23724009 and PMID:33167477
Zp3Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of ZP3 mRNACTDPMID:16483693
Zp3Rataristolochic acid A increases expressionISOZP3 (Homo sapiens)6480464aristolochic acid I results in increased expression of ZP3 mRNACTDPMID:33212167
Zp3Ratarsane affects methylationISOZP3 (Homo sapiens)6480464Arsenic affects the methylation of ZP3 geneCTDPMID:25304211
Zp3Ratarsenic atom affects methylationISOZP3 (Homo sapiens)6480464Arsenic affects the methylation of ZP3 geneCTDPMID:25304211
Zp3Ratbenzo[a]pyrene affects methylationISOZP3 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of ZP3 5' UTR and Benzo(a)pyrene affects the methylation of ZP3 promoterCTDPMID:27901495
Zp3Ratbenzo[a]pyrene diol epoxide I increases expressionISOZP3 (Homo sapiens)64804647 more ...CTDPMID:20382639
Zp3Ratbexarotene increases expressionEXP 6480464bexarotene results in increased expression of ZP3 mRNACTDPMID:16648578
Zp3Ratbis(2-chloroethyl) sulfide increases expressionISOZP3 (Homo sapiens)6480464Mustard Gas results in increased expression of ZP3 mRNACTDPMID:25102026
Zp3Ratbis(2-ethylhexyl) phthalate increases expressionISOZp3 (Mus musculus)6480464Diethylhexyl Phthalate results in increased expression of ZP3 mRNACTDPMID:33754040
Zp3Ratbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of ZP3 mRNACTDPMID:25181051 and PMID:34947998
Zp3Ratbisphenol A decreases methylationISOZp3 (Mus musculus)6480464bisphenol A results in decreased methylation of ZP3 promoterCTDPMID:27312807
Zp3Ratbisphenol A increases methylationEXP 6480464bisphenol A results in increased methylation of ZP3 geneCTDPMID:28505145

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Biological Process
1 to 20 of 70 rows

  
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Original Reference(s)
Zp3Ratbinding of sperm to zona pellucida involved_inISOZp3 (Mus musculus)1624291UniProtKB:P21754 more ...RGDPMID:11417900 and PMID:9609824
Zp3Ratbinding of sperm to zona pellucida acts_upstream_of_or_withinISOZp3 (Mus musculus)1624291PR:P15535 PMID:11739644 and PMID:9374408RGDPMID:11739644 and PMID:9374408
Zp3Ratbinding of sperm to zona pellucida acts_upstream_of_or_withinIEAUniProtKB:P10761 and ensembl:ENSMUSP000000050731600115GO_REF:0000107EnsemblGO_REF:0000107
Zp3Ratbinding of sperm to zona pellucida involved_inIBAMGI:99215 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Zp3Ratbinding of sperm to zona pellucida involved_inISOZP3 (Canis lupus familiaris)1624291 PMID:12052239RGDPMID:12052239
Zp3Ratbinding of sperm to zona pellucida involved_inISOZP3 (Homo sapiens)1624291UniProtKB:P10761 more ...RGDPMID:19004505 more ...
Zp3Ratbinding of sperm to zona pellucida involved_inIEAUniRule:UR0013767511600115GO_REF:0000104UniProtGO_REF:0000104
Zp3Ratbinding of sperm to zona pellucida involved_inISSUniProtKB:P107611600115GO_REF:0000024UniProtGO_REF:0000024
Zp3Ratblastocyst formation involved_inIEAUniProtKB:P10761 and ensembl:ENSMUSP000000050731600115GO_REF:0000107EnsemblGO_REF:0000107
Zp3Ratblastocyst formation involved_inISOZp3 (Mus musculus)1624291 PMID:20382503RGDPMID:20382503
Zp3Ratblastocyst formation involved_inISSUniProtKB:P107611600115GO_REF:0000024UniProtGO_REF:0000024
Zp3Rategg coat formation involved_inIEAUniRule:UR0013767511600115GO_REF:0000104UniProtGO_REF:0000104
Zp3Rategg coat formation involved_inIEAUniProtKB:P10761 and ensembl:ENSMUSP000000050731600115GO_REF:0000107EnsemblGO_REF:0000107
Zp3Rategg coat formation involved_inISOZp3 (Mus musculus)1624291 PMID:14645511 and PMID:18420282RGDPMID:14645511 and PMID:18420282
Zp3Rategg coat formation involved_inIBAMGI:99215 and PANTHER:PTN0001716621600115GO_REF:0000033GO_CentralGO_REF:0000033
Zp3Rategg coat formation involved_inISSUniProtKB:P107611600115GO_REF:0000024UniProtGO_REF:0000024
Zp3Rathumoral immune response mediated by circulating immunoglobulin involved_inIEAUniProtKB:P10761 and ensembl:ENSMUSP000000050731600115GO_REF:0000107EnsemblGO_REF:0000107
Zp3Rathumoral immune response mediated by circulating immunoglobulin involved_inISOZp3 (Mus musculus)1624291 PMID:20382503RGDPMID:20382503
Zp3Rathumoral immune response mediated by circulating immunoglobulin involved_inISOZP3 (Canis lupus familiaris)1624291 PMID:12052239RGDPMID:12052239
Zp3Rathumoral immune response mediated by circulating immunoglobulin involved_inISSUniProtKB:P107611600115GO_REF:0000024UniProtGO_REF:0000024
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Cellular Component
1 to 19 of 19 rows

  
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Original Reference(s)
Zp3Ratcollagen-containing extracellular matrix located_inISSUniProtKB:P107611600115GO_REF:0000024UniProtGO_REF:0000024
Zp3Ratcollagen-containing extracellular matrix located_inISOZp3 (Mus musculus)1624291 PMID:11906903 and PMID:19052627RGDPMID:11906903 and PMID:19052627
Zp3Ratcollagen-containing extracellular matrix located_inISSUniProtKB:P217541600115GO_REF:0000024UniProtGO_REF:0000024
Zp3Ratcollagen-containing extracellular matrix located_inISOZP3 (Homo sapiens)1624291 PMID:19246320RGDPMID:19246320
Zp3Rategg coat located_inIEAUniProtKB-SubCell:SL-05401600115GO_REF:0000044UniProtGO_REF:0000044
Zp3Rategg coat located_inIEAUniRule:UR0013767511600115GO_REF:0000104UniProtGO_REF:0000104
Zp3Rategg coat located_inISOZP3 (Homo sapiens)1624291 PMID:29895852RGDPMID:29895852
Zp3Rategg coat located_inISSUniProtKB:P217541600115GO_REF:0000024UniProtGO_REF:0000024
Zp3Ratextracellular matrix is_active_inIBAMGI:99215 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Zp3Ratextracellular region located_inIEAUniProtKB-KW:KW-09641600115GO_REF:0000043UniProtGO_REF:0000043
Zp3Ratextracellular space located_inISSUniProtKB:P217541600115GO_REF:0000024UniProtGO_REF:0000024
Zp3Ratextracellular space located_inISOZP3 (Homo sapiens)1624291 PMID:19246320RGDPMID:19246320
Zp3Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Zp3Ratplasma membrane located_inISSUniProtKB:P107611600115GO_REF:0000024UniProtGO_REF:0000024
Zp3Ratplasma membrane located_inIEAUniRule:UR0013767511600115GO_REF:0000104UniProtGO_REF:0000104
Zp3Ratplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043
Zp3Ratplasma membrane located_inIEAUniProtKB:P10761 and ensembl:ENSMUSP000000050731600115GO_REF:0000107EnsemblGO_REF:0000107
Zp3Ratplasma membrane located_inISOZp3 (Mus musculus)1624291 PMID:11417900 more ...RGDPMID:11417900 more ...
Zp3Ratplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044
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Molecular Function
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Original Reference(s)
Zp3Ratacrosin binding enablesISOZP3 (Homo sapiens)1624291UniProtKB:P10323 and PMID:15950651RGDPMID:15950651
Zp3Ratacrosin binding enablesIBAPANTHER:PTN000171662 and UniProtKB:P217541600115GO_REF:0000033GO_CentralGO_REF:0000033
Zp3Ratcarbohydrate binding enablesISSUniProtKB:P217541600115GO_REF:0000024UniProtGO_REF:0000024
Zp3Ratcarbohydrate binding enablesISOZP3 (Homo sapiens)1624291 PMID:19246320RGDPMID:19246320
Zp3Ratidentical protein binding enablesISOZP3 (Homo sapiens) and UniProtKB:P21754-11624291UniProtKB:P21754-1 and PMID:28886344RGDPMID:28886344
Zp3Ratidentical protein binding enablesISOZP3 (Homo sapiens)1624291UniProtKB:P21754 and PMID:26879157RGDPMID:26879157
Zp3Ratprotein binding enablesISOZP3 (Homo sapiens)1624291UniProtKB:O14917 more ...RGDPMID:15950651 more ...
Zp3Ratprotein binding enablesISOZp3 (Mus musculus)1624291PR:P15535 more ...RGDPMID:11417900 more ...
Zp3Ratprotein binding enablesISOZP3 (Homo sapiens) and UniProtKB:P21754-31624291UniProtKB:O75508 more ...RGDPMID:32296183
Zp3Ratreceptor ligand activity enablesIEAUniProtKB:P10761 and ensembl:ENSMUSP000000050731600115GO_REF:0000107EnsemblGO_REF:0000107
Zp3Ratreceptor ligand activity enablesISOZp3 (Mus musculus)1624291 PMID:10793136 and PMID:17258189RGDPMID:10793136 and PMID:17258189
Zp3Ratreceptor ligand activity enablesISSUniProtKB:P107611600115GO_REF:0000024UniProtGO_REF:0000024
Zp3Ratstructural constituent of egg coat enablesIEAUniRule:UR0013767511600115GO_REF:0000104UniProtGO_REF:0000104
Zp3Ratstructural constituent of egg coat enablesIEAUniProtKB:P10761 and ensembl:ENSMUSP000000050731600115GO_REF:0000107EnsemblGO_REF:0000107
Zp3Ratstructural constituent of egg coat enablesISOZp3 (Mus musculus)1624291 PMID:14645511RGDPMID:14645511
Zp3Ratstructural constituent of egg coat enablesISSUniProtKB:P488331600115GO_REF:0000024UniProtGO_REF:0000024
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#
Reference Title
Reference Citation
1. Rat zona pellucida glycoproteins: molecular cloning and characterization of the three major components. Akatsuka K, etal., Mol Reprod Dev 1998 Dec;51(4):454-67.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:9374408   PMID:9609824   PMID:10793136   PMID:11417900   PMID:11739644   PMID:11751269   PMID:11906903   PMID:12052239   PMID:12477932   PMID:14645511   PMID:15579591   PMID:15950651  
PMID:16342937   PMID:17047254   PMID:17258189   PMID:18420282   PMID:18667750   PMID:18667753   PMID:19004505   PMID:19052627   PMID:19246320   PMID:19700799   PMID:20382503   PMID:20394732  
PMID:26879157   PMID:28886344   PMID:29895852   PMID:33624742  



Zp3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81226,327,161 - 26,334,126 (-)NCBIGRCr8
mRatBN7.21220,690,547 - 20,697,513 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1220,690,547 - 20,697,513 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1221,831,035 - 21,838,010 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01222,443,745 - 22,450,720 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01221,508,864 - 21,516,408 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01223,735,225 - 23,752,734 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1223,735,223 - 23,742,190 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01225,733,873 - 25,740,838 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41221,805,746 - 21,812,711 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11221,792,837 - 21,799,583 (-)NCBI
Celera1222,453,873 - 22,460,838 (-)NCBICelera
Cytogenetic Map12q12NCBI
ZP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38776,397,522 - 76,442,069 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl776,397,518 - 76,442,071 (+)EnsemblGRCh38hg38GRCh38
GRCh37776,026,839 - 76,071,386 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36775,864,804 - 75,909,324 (+)NCBINCBI36Build 36hg18NCBI36
Build 34775,671,518 - 75,716,038NCBI
Celera770,895,359 - 70,931,910 (+)NCBICelera
Cytogenetic Map7q11.23NCBI
HuRef771,113,333 - 71,158,989 (+)NCBIHuRef
CHM1_1775,957,109 - 76,001,648 (+)NCBICHM1_1
T2T-CHM13v2.0777,685,187 - 77,730,456 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2775,359,905 - 75,404,452 (+)NCBI
Zp3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395136,008,959 - 136,017,478 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5136,008,953 - 136,017,478 (+)EnsemblGRCm39 Ensembl
GRCm385135,980,105 - 135,988,624 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5135,980,099 - 135,988,624 (+)EnsemblGRCm38mm10GRCm38
MGSCv375136,455,975 - 136,464,494 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365136,264,732 - 136,273,251 (+)NCBIMGSCv36mm8
Celera5132,991,486 - 133,024,448 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map575.62NCBI
Zp3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495545615,013,472 - 15,020,809 (+)NCBIChiLan1.0ChiLan1.0
ZP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2693,508,359 - 93,526,170 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17141,772,997 - 141,790,809 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0767,574,932 - 67,592,757 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1782,872,676 - 82,891,655 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl782,844,162 - 82,891,655 (+)Ensemblpanpan1.1panPan2
ZP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.167,586,212 - 7,594,610 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl67,585,970 - 7,594,610 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha69,281,828 - 9,290,191 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.067,406,839 - 7,415,182 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl67,406,839 - 7,415,182 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.167,375,722 - 7,384,085 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.067,338,676 - 7,347,061 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.067,501,843 - 7,510,213 (+)NCBIUU_Cfam_GSD_1.0
Zp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344132,014,297 - 132,023,299 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365432,013,231 - 2,022,270 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl39,934,760 - 9,944,941 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.139,934,760 - 9,944,924 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.239,837,980 - 9,848,145 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap3pter-p15NCBI
ZP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12810,534,383 - 10,579,828 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2810,562,455 - 10,579,825 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660705,838,035 - 5,855,397 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zp3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474015,037,943 - 15,044,193 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474015,037,818 - 15,044,207 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Zp3
67 total Variants

Predicted Target Of
Summary Value
Count of predictions:56
Count of miRNA genes:52
Interacting mature miRNAs:56
Transcripts:ENSRNOT00000001952
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 55 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
61443Btemp2Thermal response to stress QTL 23.30.000094body temperature trait (VT:0005535)core body temperature (CMO:0001036)121502518320794014Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12852542328064601Rat
737822Alc10Alcohol consumption QTL 102.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)121961087040218516Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)121587265332974238Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123297788Rat

1 to 10 of 55 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
3 1 2 40 19 18 3 14 3 1 35 20 37 9 47 15



Ensembl Acc Id: ENSRNOT00000001952   ⟹   ENSRNOP00000001952
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1220,690,547 - 20,697,513 (-)Ensembl
Rnor_6.0 Ensembl1223,735,223 - 23,742,190 (-)Ensembl
RefSeq Acc Id: NM_053762   ⟹   NP_446214
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81226,327,161 - 26,334,126 (-)NCBI
mRatBN7.21220,690,547 - 20,697,513 (-)NCBI
Rnor_6.01223,735,225 - 23,742,190 (-)NCBI
Rnor_5.01225,733,873 - 25,740,838 (-)NCBI
RGSC_v3.41221,805,746 - 21,812,711 (-)RGD
Celera1222,453,873 - 22,460,838 (-)RGD
Sequence:
Protein RefSeqs NP_446214 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI27489 (Get FASTA)   NCBI Sequence Viewer  
  BAA24456 (Get FASTA)   NCBI Sequence Viewer  
  EDM13334 (Get FASTA)   NCBI Sequence Viewer  
  EDM13335 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000001952
GenBank Protein P97708 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_446214   ⟸   NM_053762
- Peptide Label: precursor
- UniProtKB: A1L124 (UniProtKB/TrEMBL),   F7EZ23 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000001952   ⟸   ENSRNOT00000001952
ZP

Name Modeler Protein Id AA Range Protein Structure
AF-P97708-F1-model_v2 AlphaFold P97708 1-424 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 27 of 27 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-19643 BioCyc
Ensembl Genes ENSRNOG00000001434 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000001952 ENTREZGENE
Gene3D-CATH 2.60.40.4100 UniProtKB/Swiss-Prot
  Zona pellucida, ZP-N domain UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7308805 IMAGE-MGC_LOAD
InterPro ZP-C UniProtKB/Swiss-Prot
  ZP_chr UniProtKB/Swiss-Prot
  ZP_dom UniProtKB/Swiss-Prot
  ZP_dom_CS UniProtKB/Swiss-Prot
KEGG Report rno:114639 UniProtKB/Swiss-Prot
MGC_CLONE MGC:156611 IMAGE-MGC_LOAD
NCBI Gene 114639 ENTREZGENE
PANTHER PTHR11576:SF2 UniProtKB/Swiss-Prot
  ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 UniProtKB/Swiss-Prot
Pfam Zona_pellucida UniProtKB/Swiss-Prot
PhenoGen Zp3 PhenoGen
PRINTS ZPELLUCIDA UniProtKB/Swiss-Prot
PROSITE ZP_1 UniProtKB/Swiss-Prot
  ZP_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001434 RatGTEx
SMART SM00241 UniProtKB/Swiss-Prot
UniProt A1L124 ENTREZGENE, UniProtKB/TrEMBL
  A6J096_RAT UniProtKB/TrEMBL
  F7EZ23 ENTREZGENE, UniProtKB/TrEMBL
  P97708 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary O55084 UniProtKB/Swiss-Prot
1 to 27 of 27 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-18 Zp3  zona pellucida glycoprotein 3  Zp3  zona pellucida glycoprotein 3 (sperm receptor)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-25 Zp3  zona pellucida glycoprotein 3 (sperm receptor)  Zp3  zona pellucida glycoprotein 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Zp3  zona pellucida glycoprotein 3      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Zp3  zona pellucida glycoprotein 3      Symbol and Name status set to provisional 70820 PROVISIONAL

Note Type Note Reference
gene_domains contains six potential N-glycosylation sites and 75 Ser/Thr residues which are possible O-glycosylation sites 634535