Selenbp1 (selenium binding protein 1) - Rat Genome Database

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Gene: Selenbp1 (selenium binding protein 1) Rattus norvegicus
Analyze
Symbol: Selenbp1
Name: selenium binding protein 1
RGD ID: 620571
Description: Predicted to enable methanethiol oxidase activity. Predicted to be involved in protein transport. Predicted to act upstream of or within brown fat cell differentiation. Predicted to be located in cytosol; fibrillar center; and membrane. Orthologous to human SELENBP1 (selenium binding protein 1); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 56 kDa selenium-binding protein; methanethiol oxidase; MTO; rSBP; SBP56; Selenbp2; selenium binding protein 2; selenium-binding protein 1; selenium-binding protein 2; SP56
RGD Orthologs
Human
Mouse
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
NCBI Annotation Information: Note: LOC103689947 appears to be a duplicate placement of Selenbp1 on Rnor_6.0 (Annot. Release 105) that is present on Rn_Celera but is absent from the previous reference assembly (Rnor_5.0) and not supported by syntenic regions in mouse and human. It appears that Selenbp1 was annotated on Rn_Celera as LOC103689947. Selenbp1 annotation on Rnor_6.0 is thus supported by annotation on Rn_Celera (as LOC103689947) and additionally, synteny with mouse and human. BLAST analysis of the LOC103689947 underlying component AABR07012460.1 shows 99% identity with a ~60 kb region of NC_005101.4 including where Selenbp1 is annotated. Annotation of Selenbp1 at this location on Rnor_6.0 is supported by annotation of LOC103689947 on Rn_Celera. This apparent duplication could be explained by misassembly of several underlying components on Rnor_6.0. [17 Mar 2015]
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82185,183,022 - 185,193,612 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2185,183,004 - 185,194,295 (+)EnsemblGRCr8
mRatBN7.22182,494,004 - 182,504,594 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2182,493,978 - 182,504,594 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2190,158,745 - 190,169,478 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02187,954,452 - 187,965,170 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02182,791,220 - 182,801,953 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02195,416,472 - 195,423,665 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2195,416,469 - 195,423,787 (-)Ensemblrn6Rnor6.0
Rnor_6.0 Ensembl2196,105,569 - 196,113,149 (-)Ensemblrn6Rnor6.0
Rnor_5.02214,896,716 - 214,903,904 (-)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.02215,588,465 - 215,598,473 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42189,840,450 - 189,881,332 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2175,037,375 - 175,046,988 (+)NCBICelera
RGSC_v3.12189,785,972 - 189,796,482 (+)NCBI
Cytogenetic Map2q34NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-alpha-phellandrene  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrotoluene  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
2-amino-2-deoxy-D-glucopyranose  (EXP)
2-bromohexadecanoic acid  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
4-hydroxynon-2-enal  (ISO)
4-nitrophenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (EXP)
all-trans-retinoic acid  (EXP)
alpha-phellandrene  (ISO)
alpha-pinene  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
amphetamine  (EXP)
aniline  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
Benzo[k]fluoranthene  (ISO)
beta-D-glucosamine  (EXP)
bilirubin IXalpha  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bleomycin A2  (EXP)
bromobenzene  (EXP)
Bufotalin  (ISO)
buta-1,3-diene  (ISO)
C60 fullerene  (EXP)
cadmium atom  (EXP,ISO)
cadmium dichloride  (ISO)
cadmium sulfate  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
chlorohydrocarbon  (EXP)
chloroprene  (ISO)
ciguatoxin CTX1B  (ISO)
clobetasol  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
coumarin  (EXP)
coumestrol  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
D-penicillamine  (EXP)
dexamethasone  (ISO)
dibenzofurans  (ISO)
dibutyl phthalate  (EXP,ISO)
diethylstilbestrol  (ISO)
dimethyl sulfoxide  (ISO)
dimethylarsinic acid  (EXP)
dioxygen  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
erlotinib hydrochloride  (ISO)
estriol  (ISO)
estrone  (ISO)
flutamide  (EXP)
folic acid  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glycerol  (ISO)
glyphosate  (ISO)
indometacin  (ISO)
inulin  (ISO)
isoflavones  (ISO)
ivermectin  (ISO)
lead diacetate  (ISO)
leflunomide  (EXP)
lipopolysaccharide  (ISO)
manganese(II) chloride  (EXP)
methanethiol  (ISO)
methapyrilene  (EXP)
methimazole  (EXP)
methoxychlor  (ISO)
methylmercury chloride  (EXP,ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-Nitrosopyrrolidine  (ISO)
naphthalene  (ISO)
nefazodone  (EXP)
nickel atom  (ISO)
nitrofen  (EXP)
Nonylphenol  (ISO)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
p-toluidine  (EXP)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
phenethyl isothiocyanate  (EXP)
phenylephrine  (EXP)
phenylmercury acetate  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
progesterone  (EXP,ISO)
propane-1,2-diol  (ISO)
propiconazole  (ISO)
quercetin  (EXP,ISO)
resveratrol  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
Soman  (EXP)
succimer  (ISO)
sulfadimethoxine  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tanespimycin  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
thiram  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA)
membrane  (IEA)
nucleolus  (IEA,ISO)
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
2. Different patterns of regulation of the genes encoding the closely related 56 kDa selenium- and acetaminophen-binding proteins in normal tissues and during carcinogenesis. Lanfear J, etal., Carcinogenesis 1993 Mar;14(3):335-40.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
8. Integrated microarray analysis provided novel insights to the pathogenesis of glaucoma. Wang J, etal., Mol Med Rep. 2017 Dec;16(6):8735-8746. doi: 10.3892/mmr.2017.7711. Epub 2017 Oct 4.
Additional References at PubMed
PMID:15632090   PMID:16502470   PMID:18492766   PMID:19056867   PMID:23376485   PMID:23533145   PMID:25931508   PMID:27578022  


Genomics

Comparative Map Data
Selenbp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82185,183,022 - 185,193,612 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2185,183,004 - 185,194,295 (+)EnsemblGRCr8
mRatBN7.22182,494,004 - 182,504,594 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2182,493,978 - 182,504,594 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2190,158,745 - 190,169,478 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02187,954,452 - 187,965,170 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02182,791,220 - 182,801,953 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02195,416,472 - 195,423,665 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2195,416,469 - 195,423,787 (-)Ensemblrn6Rnor6.0
Rnor_6.0 Ensembl2196,105,569 - 196,113,149 (-)Ensemblrn6Rnor6.0
Rnor_5.02214,896,716 - 214,903,904 (-)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.02215,588,465 - 215,598,473 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42189,840,450 - 189,881,332 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2175,037,375 - 175,046,988 (+)NCBICelera
RGSC_v3.12189,785,972 - 189,796,482 (+)NCBI
Cytogenetic Map2q34NCBI
SELENBP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381151,364,304 - 151,372,705 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1151,364,302 - 151,372,716 (-)Ensemblhg38GRCh38
GRCh371151,336,780 - 151,345,181 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361149,603,404 - 149,611,788 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341148,149,853 - 148,158,237NCBI
Celera1124,452,070 - 124,460,453 (-)NCBICelera
Cytogenetic Map1q21.3NCBI
HuRef1122,714,749 - 122,723,196 (-)NCBIHuRef
CHM1_11152,732,433 - 152,740,866 (-)NCBICHM1_1
T2T-CHM13v2.01150,487,989 - 150,496,432 (-)NCBIT2T-CHM13v2.0
Selenbp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39394,840,394 - 94,852,069 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl394,840,367 - 94,852,069 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38394,933,083 - 94,944,758 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl394,933,056 - 94,944,758 (+)Ensemblmm10GRCm38
MGSCv37394,737,005 - 94,748,680 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36395,018,487 - 95,030,162 (+)NCBIMGSCv36mm8
Celera396,364,442 - 96,376,009 (+)NCBICelera
Cytogenetic Map3F2.1NCBI
cM Map340.74NCBI
Selenbp1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1362,308,846 - 62,319,589 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Selenbp1
103 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:174
Count of miRNA genes:136
Interacting mature miRNAs:143
Transcripts:ENSRNOT00000028510
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2163997722225110681Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2169358774214358774Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2170656145239614549Rat
631566Bp90Blood pressure QTL 900.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2149957381221199885Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845370229470703Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)283465462229820014Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2138595962205135428Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
1581576Pur7Proteinuria QTL 70.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)280396178220931218Rat
1581578Cm49Cardiac mass QTL 494.90.01heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2145807215220931416Rat
152025245Scl81Serum cholesterol level QTL 813.49blood cholesterol amount (VT:0000180)2124537199209621565Rat
631198Cm22Cardiac mass QTL 224.30.0008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)278269809208420281Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2122597372215234002Rat
12879836Kidm61Kidney mass QTL 610.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2154723085199723085Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)280396178220931218Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2145807215190807215Rat
12879837Am2Aortic mass QTL 20.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2154723085199723085Rat
1302793Bw16Body weight QTL 1650.0001body mass (VT:0001259)body weight (CMO:0000012)2159440891205135267Rat
10043139Iddm55Insulin dependent diabetes mellitus QTL 553.10.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2150313808195313808Rat
12879838Cm86Cardiac mass QTL 860.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2154723085199723085Rat
12879839Cm85Cardiac mass QTL 850.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2154723085199723085Rat
1549833Bp257Blood pressure QTL 2570.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2170652929215652929Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2159440891220931218Rat
4889834Pur24Proteinuria QTL 245.80.014urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)2171994826205135428Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2143565208188565208Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
12879840Bw179Body weight QTL 1790.005body mass (VT:0001259)body weight (CMO:0000012)2154723085199723085Rat
1581502Esta3Estrogen-induced thymic atrophy QTL 3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2139067258192287892Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2184856304229856304Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2184856304229856304Rat
1359032Hrtrt18Heart rate QTL 18heart pumping trait (VT:2000009)heart rate (CMO:0000002)2159440760195313808Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2144882354205135428Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845182205135428Rat
1357991Ael2Aortic elastin QTL 24.20.000071aorta elastin amount (VT:0003905)aortic elastin2169227906214227906Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)283400752223709938Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2184856304229856304Rat
1578671Bmd10Bone mineral density QTL 105.4femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)2175931416220931416Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2151869660251712708Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)280396034220931416Rat
2300189Bmd48Bone mineral density QTL 485.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)2182024327227024327Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)278269809205135428Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2159440760228950743Rat
2301408Kidm36Kidney mass QTL 360.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2184482291229482291Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2143344967251712708Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2143746578205135428Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2143344967251712708Rat
1598805Memor8Memory QTL 83exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2150096616195096616Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2114384617215381366Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2145306936212705578Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2113746222205135428Rat
61401Niddm2Non-insulin dependent diabetes mellitus QTL 24.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2147287892192287892Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2114384617215381366Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2151869660223841096Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2117415288205135428Rat
1598833Bp295Blood pressure QTL 2953.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150096616195096616Rat
61417Cia10Collagen induced arthritis QTL 103.4joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)2182635347227635347Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)283465462225110681Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)247856345205135428Rat
631522Bp74Blood pressure QTL 740.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2175008837220008837Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2184856304229856304Rat
7488927Bp365Blood pressure QTL 3650.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2165453811210453811Rat
7488925Bp364Blood pressure QTL 3640.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2163253030208253030Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166372086229820014Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)276328396209350714Rat

Markers in Region
D2Rat126  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr82185,223,932 - 185,224,165 (+)Marker Load Pipeline
mRatBN7.22182,534,917 - 182,535,150 (+)MAPPERmRatBN7.2
Rnor_6.02196,134,296 - 196,134,528NCBIRnor6.0
Rnor_5.02215,628,982 - 215,629,214UniSTSRnor5.0
RGSC_v3.42189,869,153 - 189,869,386RGDRGSC3.4
RGSC_v3.42189,869,154 - 189,869,386UniSTSRGSC3.4
Celera2175,076,961 - 175,077,193UniSTS
RGSC_v3.12189,828,562 - 189,828,794RGD
RH 3.4 Map21212.1UniSTS
RH 3.4 Map21212.1RGD
RH 2.0 Map2884.4RGD
SHRSP x BN Map270.0098RGD
Cytogenetic Map2q34UniSTS
RH144445  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22182,540,402 - 182,540,529 (+)MAPPERmRatBN7.2
Rnor_6.02196,139,781 - 196,139,907NCBIRnor6.0
Rnor_5.02215,634,467 - 215,634,593UniSTSRnor5.0
RGSC_v3.42189,874,639 - 189,874,765UniSTSRGSC3.4
Celera2175,082,442 - 175,082,568UniSTS
RH 3.4 Map21199.1UniSTS
Cytogenetic Map2q34UniSTS
AI072618  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22182,528,466 - 182,528,601 (+)MAPPERmRatBN7.2
Rnor_6.02196,127,845 - 196,127,979NCBIRnor6.0
Rnor_5.02215,622,531 - 215,622,665UniSTSRnor5.0
RGSC_v3.42189,862,703 - 189,862,837UniSTSRGSC3.4
Celera2175,070,511 - 175,070,645UniSTS
RH 3.4 Map21199.1UniSTS
Cytogenetic Map2q34UniSTS
BE115799  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22182,537,643 - 182,537,862 (+)MAPPERmRatBN7.2
Rnor_6.02196,137,022 - 196,137,240NCBIRnor6.0
Rnor_5.02215,631,708 - 215,631,926UniSTSRnor5.0
RGSC_v3.42189,871,880 - 189,872,098UniSTSRGSC3.4
Celera2175,079,683 - 175,079,901UniSTS
RH 3.4 Map21197.2UniSTS
Cytogenetic Map2q34UniSTS
RH135301  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22182,495,388 - 182,495,596 (+)MAPPERmRatBN7.2
Rnor_6.02196,096,163 - 196,096,370NCBIRnor6.0
Rnor_6.02195,407,048 - 195,407,255NCBIRnor6.0
Rnor_5.02215,589,882 - 215,590,089UniSTSRnor5.0
Rnor_5.02214,887,287 - 214,887,494UniSTSRnor5.0
RGSC_v3.42189,831,021 - 189,831,228UniSTSRGSC3.4
Celera2175,038,799 - 175,039,006UniSTS
RH 3.4 Map21200.9UniSTS
Cytogenetic Map2q34UniSTS
BI282436  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22182,504,372 - 182,504,544 (-)MAPPERmRatBN7.2
Rnor_6.02196,105,642 - 196,105,813NCBIRnor6.0
Rnor_6.02195,416,527 - 195,416,698NCBIRnor6.0
Rnor_5.02215,598,247 - 215,598,418UniSTSRnor5.0
Rnor_5.02214,896,766 - 214,896,937UniSTSRnor5.0
RGSC_v3.42189,840,500 - 189,840,671UniSTSRGSC3.4
Celera2175,046,762 - 175,046,933UniSTS
RH 3.4 Map21195.1UniSTS
Cytogenetic Map2q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 1 22 38 15 23 11 63 11 166 98 11 34 48 40 12 11 11

Sequence


Ensembl Acc Id: ENSRNOT00000071603   ⟹   ENSRNOP00000064790
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2185,183,094 - 185,194,295 (+)Ensembl
mRatBN7.2 Ensembl2182,497,282 - 182,504,594 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000088465   ⟹   ENSRNOP00000071154
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2185,186,553 - 185,194,295 (+)Ensembl
mRatBN7.2 Ensembl2182,497,535 - 182,504,594 (+)Ensembl
Rnor_6.0 Ensembl2196,105,569 - 196,113,149 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097461   ⟹   ENSRNOP00000083317
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2185,183,004 - 185,194,295 (+)Ensembl
mRatBN7.2 Ensembl2182,493,978 - 182,504,594 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101667   ⟹   ENSRNOP00000094007
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2185,183,004 - 185,194,295 (+)Ensembl
mRatBN7.2 Ensembl2182,493,978 - 182,504,594 (+)Ensembl
RefSeq Acc Id: NM_001329893   ⟹   NP_001316822
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82185,183,022 - 185,193,612 (+)NCBI
mRatBN7.22182,494,004 - 182,504,594 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001316822 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH74008 (Get FASTA)   NCBI Sequence Viewer  
  BAB83134 (Get FASTA)   NCBI Sequence Viewer  
  EDL85767 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000094007
  ENSRNOP00000094007.1
GenBank Protein Q8VIF7 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Acc Id: ENSRNOP00000071154   ⟸   ENSRNOT00000088465
Ensembl Acc Id: ENSRNOP00000064790   ⟸   ENSRNOT00000071603
Ensembl Acc Id: ENSRNOP00000083317   ⟸   ENSRNOT00000097461
Ensembl Acc Id: ENSRNOP00000094007   ⟸   ENSRNOT00000101667
RefSeq Acc Id: NP_001316822   ⟸   NM_001329893
- UniProtKB: Q8VIF7 (UniProtKB/Swiss-Prot),   A6K2T3 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VIF7-F1-model_v2 AlphaFold Q8VIF7 1-472 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620571 AgrOrtholog
Ensembl Genes ENSRNOG00000047158 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00000053812 Ensembl
Ensembl Transcript ENSRNOT00000101667 ENTREZGENE
  ENSRNOT00000101667.1 UniProtKB/Swiss-Prot
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7100467 IMAGE-MGC_LOAD
InterPro Se-bd UniProtKB/Swiss-Prot
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:103689947 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91524 IMAGE-MGC_LOAD
NCBI Gene Selenbp1 ENTREZGENE
PANTHER METHANETHIOL OXIDASE UniProtKB/Swiss-Prot
  PTHR23300 UniProtKB/Swiss-Prot
Pfam SBP56 UniProtKB/Swiss-Prot
PhenoGen Selenbp1 PhenoGen
RatGTEx ENSRNOG00000047158 RatGTEx
  ENSRNOG00000053812 RatGTEx
Superfamily-SCOP 3-carboxy-cis,cis-mucoante lactonizing enzyme UniProtKB/Swiss-Prot
UniProt A0A0G2JZR8_RAT UniProtKB/TrEMBL
  A0A8I5ZWC7_RAT UniProtKB/TrEMBL
  A6K2T3 ENTREZGENE, UniProtKB/TrEMBL
  F1LRJ9_RAT UniProtKB/TrEMBL
  Q8VIF7 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-03-01 Selenbp1  selenium binding protein 1  Selenbp2  selenium binding protein 2  Data merged from RGD:9292945 737654 PROVISIONAL
2021-12-20 Selenbp2  selenium binding protein 2  LOC103689947  selenium-binding protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-08-25 LOC103689947  selenium-binding protein 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-02-22 Selenbp1  selenium binding protein 1  Selenbp1  selenium binding protein 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Selenbp1  selenium binding protein 2  Selenbp2    Symbol and Name updated 1299863 APPROVED
2002-08-07 Selenbp2  selenium binding protein 2      Symbol and Name status set to provisional 70820 PROVISIONAL