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Gene: Cabp1 (calcium binding protein 1) Rattus norvegicus

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Symbol:

Cabp1

Name:

calcium binding protein 1

RGD ID:

620385

Description:

Enables several functions, including nuclear localization sequence binding activity; transmembrane transporter binding activity; and type 3 metabotropic glutamate receptor binding activity. Involved in negative regulation of cell communication by electrical coupling; negative regulation of protein import into nucleus; and postsynapse to nucleus signaling pathway. Located in several cellular components, including neuronal cell body; postsynaptic density; and subplasmalemmal coating. Part of protein-containing complex. Is active in glutamatergic synapse and postsynaptic density, intracellular component. Biomarker of temporal lobe epilepsy. Orthologous to human CABP1 (calcium binding protein 1); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 4,4'-sulfonyldiphenol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

calcium-binding protein 1; caldendrin; LOC108353433; uncharacterized LOC108353433

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CABP1 (calcium binding protein 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Cabp1 (calcium binding protein 1)	RGD	RGD
Chinchilla lanigera (long-tailed chinchilla):	Cabp1 (calcium binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CABP1 (calcium binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CABP1 (calcium binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cabp1 (calcium binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CABP1 (calcium binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CABP1 (calcium binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cabp1 (calcium binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Cabp1 (calcium binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	PCP2 (Purkinje cell protein 2)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	CABP1 (calcium binding protein 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Cabp1 (calcium binding protein 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Cabp1 (calcium binding protein 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cabp1a (calcium binding protein 1a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cabp1b (calcium binding protein 1b)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	cabp1b (calcium binding protein 1b)	Alliance	DIOPT (Ensembl Compara\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	cal-5	Alliance	DIOPT (Ensembl Compara\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	cabp1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	47,045,914 - 47,109,614 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	47,085,292 - 47,109,611 (+)	Ensembl				GRCr8
mRatBN7.2	12	41,385,234 - 41,448,930 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	41,378,897 - 41,448,927 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	42,591,942 - 42,616,455 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	43,205,596 - 43,230,109 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	42,266,164 - 42,290,676 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	47,185,449 - 47,209,785 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	47,179,664 - 47,209,784 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	48,980,523 - 49,004,882 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	42,696,383 - 42,720,566 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	43,043,462 - 43,067,622 (+)	NCBI		Celera
RGSC_v3.1	12	42,568,234 - 42,583,529 (+)	NCBI
Cytogenetic Map	12	q16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Chemical and Drug Induced Liver Injury (IEP)

schizophrenia (ISO)

Serotonin Syndrome (IEP)

temporal lobe epilepsy (IEP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

aristolochic acid A (ISO)

arsenite(3-) (EXP)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bis(2-chloroethyl) sulfide (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP,ISO)

butanal (ISO)

CGP 52608 (ISO)

copper(II) sulfate (ISO)

Cuprizon (EXP)

cyclophosphamide (EXP)

diarsenic trioxide (ISO)

dibutyl phthalate (ISO)

dioxygen (ISO)

ethylparaben (ISO)

fulvestrant (ISO)

genistein (ISO)

gentamycin (EXP)

lead(0) (ISO)

methapyrilene (ISO)

mono(2-ethylhexyl) phthalate (ISO)

N-methyl-4-phenylpyridinium (EXP)

ochratoxin A (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorohexanesulfonic acid (ISO)

perfluorooctanoic acid (ISO)

propanal (ISO)

resveratrol (ISO)

S-nitrosoglutathione (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

tremolite asbestos (ISO)

trichloroethene (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

modification of postsynaptic actin cytoskeleton (ISO)

negative regulation of cell communication by electrical coupling (IDA)

negative regulation of protein import into nucleus (IMP)

negative regulation of voltage-gated calcium channel activity (IDA)

phototransduction (IBA)

postsynapse to nucleus signaling pathway (IDA,IEP,IMP)

regulation of synaptic plasticity (NAS)

regulation of voltage-gated calcium channel activity (IDA)

visual perception (IBA,IEA,ISO,ISS)

Cellular Component

axon (IDA)

cytoplasm (IDA,IEA)

cytoskeleton (IEA)

dendrite (IDA)

glutamatergic synapse (IDA,IEP,IMP,ISO)

Golgi membrane (IEA,ISO)

neuronal cell body (IDA)

nucleus (IDA)

perinuclear region of cytoplasm (IDA)

plasma membrane (IBA,IEA,ISO)

postsynaptic density (IBA,IDA,IEA,ISO)

postsynaptic density, intracellular component (IDA)

protein-containing complex (IDA)

secretory granule (IDA)

subplasmalemmal coating (IDA)

Molecular Function

calcium channel regulator activity (IBA)

calcium ion binding (IDA,IEA)

calcium-dependent protein binding (IDA,IEA,IPI,ISO)

identical protein binding (IPI)

metal ion binding (IEA)

nuclear localization sequence binding (IDA)

protein binding (IPI,ISO)

protein domain specific binding (IPI)

transmembrane transporter binding (IPI)

type 3 metabotropic glutamate receptor binding (IPI)

Molecular Pathway Annotations Click to see Annotation Detail View

calcium/calcium-mediated signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	A reduced number of cortical neurons show increased Caldendrin protein levels in chronic schizophrenia.	Bernstein HG, etal., Schizophr Res. 2007 Nov;96(1-3):246-56. doi: 10.1016/j.schres.2007.05.038. Epub 2007 Aug 23.
2.	Ca2+ binding protein-1 inhibits Ca2+ currents and exocytosis in bovine chromaffin cells.	Chen ML, etal., J Biomed Sci. 2008 Mar;15(2):169-81. Epub 2007 Oct 25.
3.	Caldendrin-Jacob: a protein liaison that couples NMDA receptor signalling to the nucleus.	Dieterich DC, etal., PLoS Biol. 2008 Feb;6(2):e34. doi: 10.1371/journal.pbio.0060034.
4.	Dynamic cellular translocation of caldendrin is facilitated by the Ca2+-myristoyl switch of recoverin.	Fries R, etal., J Neurochem. 2010 Jun;113(5):1150-62. doi: 10.1111/j.1471-4159.2010.06676.x. Epub 2010 Mar 17.
5.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
7.	Association of Caldendrin splice isoforms with secretory vesicles in neurohypophyseal axons and the pituitary.	Landwehr M, etal., FEBS Lett. 2003 Jul 17;547(1-3):189-92.
8.	The neuron-specific Ca2+-binding protein caldendrin: gene structure, splice isoforms, and expression in the rat central nervous system.	Laube G, etal., Mol Cell Neurosci. 2002 Mar;19(3):459-75. doi: 10.1006/mcne.2001.1078.
9.	Differential modulation of Ca(v)2.1 channels by calmodulin and Ca2+-binding protein 1.	Lee A, etal., Nat Neurosci 2002 Mar;5(3):210-7.
10.	The diversity of calcium sensor proteins in the regulation of neuronal function.	McCue HV, etal., Cold Spring Harb Perspect Biol. 2010 Aug;2(8):a004085. doi: 10.1101/cshperspect.a004085. Epub 2010 Jul 28.
11.	Ca2+-dependent binding of calcium-binding protein 1 to presynaptic group III metabotropic glutamate receptors and blockage by phosphorylation of the receptors.	Nakajima Y Biochem Biophys Res Commun. 2011 Sep 9;412(4):602-5. doi: 10.1016/j.bbrc.2011.08.006. Epub 2011 Aug 10.
12.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
13.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
15.	Caldendrin, a novel neuronal calcium-binding protein confined to the somato-dendritic compartment.	Seidenbecher CI, etal., J Biol Chem 1998 Aug 14;273(33):21324-31.
16.	Kainate-induced epileptic seizures induce a recruitment of caldendrin to the postsynaptic density in rat brain.	Smalla KH, etal., Brain Res Mol Brain Res. 2003 Aug 19;116(1-2):159-62.
17.	Altered postsynaptic-density-levels of caldendrin in the para-chloroamphetamine-induced serotonin syndrome but not in the rat ketamine model of psychosis.	Smalla KH, etal., Neurochem Res. 2009 Aug;34(8):1405-9. doi: 10.1007/s11064-009-9925-8. Epub 2009 Feb 18.
18.	Caldendrin, a neuron-specific modulator of Cav/1.2 (L-type) Ca2+ channels.	Tippens AL and Lee A, J Biol Chem. 2007 Mar 16;282(11):8464-73. Epub 2007 Jan 15.
19.	Identification of liver proteins and their roles associated with carbon tetrachloride-induced hepatotoxicity.	Wong LL, etal., Hum Exp Toxicol. 2011 Sep;30(9):1369-81. doi: 10.1177/0960327110391388. Epub 2010 Dec 7.
20.	Ca2+-binding protein-1 facilitates and forms a postsynaptic complex with Cav1.2 (L-type) Ca2+ channels.	Zhou H, etal., J Neurosci. 2004 May 12;24(19):4698-708.

Additional References at PubMed

PMID:8889548	PMID:15980432	PMID:16049184	PMID:17055077	PMID:17994197	PMID:19338761	PMID:22664934	PMID:23650371	PMID:25058677	PMID:27822497	PMID:28437073	PMID:29478916

Genomics

Comparative Map Data

Cabp1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	47,045,914 - 47,109,614 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	47,085,292 - 47,109,611 (+)	Ensembl				GRCr8
mRatBN7.2	12	41,385,234 - 41,448,930 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	41,378,897 - 41,448,927 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	42,591,942 - 42,616,455 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	43,205,596 - 43,230,109 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	42,266,164 - 42,290,676 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	47,185,449 - 47,209,785 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	47,179,664 - 47,209,784 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	48,980,523 - 49,004,882 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	42,696,383 - 42,720,566 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	43,043,462 - 43,067,622 (+)	NCBI		Celera
RGSC_v3.1	12	42,568,234 - 42,583,529 (+)	NCBI
Cytogenetic Map	12	q16	NCBI

CABP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	120,640,626 - 120,680,866 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	120,640,590 - 120,667,327 (+)	Ensembl			hg38	GRCh38
GRCh37	12	121,078,429 - 121,105,127 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	119,562,805 - 119,589,510 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	12	119,551,090 - 119,567,845	NCBI
Celera	12	120,712,715 - 120,739,394 (+)	NCBI		Celera
Cytogenetic Map	12	q24.31	NCBI
HuRef	12	118,087,780 - 118,114,466 (+)	NCBI		HuRef
CHM1_1	12	121,047,209 - 121,073,905 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	120,629,781 - 120,669,988 (+)	NCBI		T2T-CHM13v2.0

Cabp1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	115,306,750 - 115,332,440 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	115,306,748 - 115,332,440 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	115,168,691 - 115,194,381 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	115,168,689 - 115,194,381 (-)	Ensembl			mm10	GRCm38
MGSCv37	5	115,618,700 - 115,636,130 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	115,429,955 - 115,447,120 (-)	NCBI		MGSCv36	mm8
Celera	5	112,265,082 - 112,282,516 (-)	NCBI		Celera
Cytogenetic Map	5	F	NCBI
cM Map	5	55.99	NCBI

Cabp1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955455	11,000,763 - 11,016,160 (-)	Ensembl
ChiLan1.0	NW_004955455	11,000,763 - 11,068,922 (-)	NCBI	ChiLan1.0	ChiLan1.0

CABP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	128,710,772 - 128,737,428 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	128,707,150 - 128,733,803 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	118,224,046 - 118,250,696 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	121,605,979 - 121,623,960 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2

CABP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	16,492,484 - 16,523,265 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	16,494,980 - 16,525,873 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	16,758,371 - 16,789,256 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	16,768,053 - 16,789,251 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	16,719,024 - 16,749,945 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	16,794,703 - 16,825,583 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	16,836,775 - 16,867,667 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Cabp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	145,825,410 - 145,847,946 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936668	323,379 - 339,211 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936668	324,299 - 339,334 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CABP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	40,563,159 - 40,587,970 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	40,563,302 - 40,587,975 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	42,996,071 - 43,055,074 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CABP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	115,934,747 - 116,021,645 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666037	129,075,237 - 129,103,423 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cabp1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624747	13,027,844 - 13,050,165 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624747	13,027,839 - 13,050,262 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Cabp1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	16	38,634,337 - 38,660,134 (+)	NCBI		Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	310
Count of miRNA genes:	110
Interacting mature miRNAs:	123
Transcripts:	ENSRNOT00000001551, ENSRNOT00000001552, ENSRNOT00000039281
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631560	Apr1	Acute phase response QTL 1	6.1		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	24805022	52308831	Rat
70213	Niddm27	Non-insulin dependent diabetes mellitus QTL 27	3.72		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	11200494	52308831	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
8693635	Alc28	Alcohol consumption QTL 28	2.7	0.439	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	28717718	50386405	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7411643	Foco20	Food consumption QTL 20		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	25989355	52308831	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	3489416	48489416	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	18473041	52308831	Rat
1300162	Bp188	Blood pressure QTL 188	3.19		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	37764145	51558799	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200497	52308831	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	15264248	52308831	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	11743528	52308831	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
1300175	Cm5	Cardiac mass QTL 5	3.78		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	33700432	51558799	Rat
1331786	Kidm11	Kidney mass QTL 11	3.571		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	12	16187438	52308831	Rat
8693658	Alc33	Alcohol consumption QTL 33	2.1	0.68	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	28717718	49212240	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	16135029	52308831	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	16187438	51213550	Rat
1331763	Wbc2	White blood cell count QTL 2	3.162		leukocyte quantity (VT:0000217)	total white blood cell count (CMO:0000365)	12	11200494	52308831	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	11200494	52308831	Rat
1298081	Cia25	Collagen induced arthritis QTL 25	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	2747694	47747694	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	18473041	52308831	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	3087180	48087180	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7243862	Mcs30	Mammary carcinoma susceptibility QTL 30	8.62		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	12	5633306	50633306	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	16135029	52308831	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
631543	Bp83	Blood pressure QTL 83	5.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	44139558	52308831	Rat

Markers in Region

AU048814

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	41,432,447 - 41,432,668 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	47,193,179 - 47,193,399	NCBI	Rnor6.0
Rnor_5.0	12	48,988,404 - 48,988,624	UniSTS	Rnor5.0
RGSC_v3.4	12	42,704,062 - 42,704,282	UniSTS	RGSC3.4
Celera	12	43,051,095 - 43,051,315	UniSTS
Cytogenetic Map	12	q16	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
15	11	67	158	91	90	59	74	59	6	336	173	9	130	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001033675	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001033676	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_133529	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089041	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC121426	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AI111711	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ315657	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ315761	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BF523318	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Y17048	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000001551 ⟹ ENSRNOP00000001551

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	47,085,292 - 47,109,611 (+)	Ensembl
mRatBN7.2 Ensembl	12	41,424,606 - 41,448,927 (+)	Ensembl
Rnor_6.0 Ensembl	12	47,179,664 - 47,209,357 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000001552 ⟹ ENSRNOP00000001552

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	47,093,720 - 47,109,611 (+)	Ensembl
mRatBN7.2 Ensembl	12	41,433,184 - 41,448,927 (+)	Ensembl
Rnor_6.0 Ensembl	12	47,193,964 - 47,209,784 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000039281 ⟹ ENSRNOP00000033685

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	47,093,720 - 47,109,611 (+)	Ensembl
mRatBN7.2 Ensembl	12	41,433,233 - 41,448,927 (+)	Ensembl
Rnor_6.0 Ensembl	12	47,193,964 - 47,209,784 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000101243 ⟹ ENSRNOP00000078200

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	41,436,635 - 41,448,927 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000114073 ⟹ ENSRNOP00000092742

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	47,102,676 - 47,109,611 (+)	Ensembl
mRatBN7.2 Ensembl	12	41,378,897 - 41,448,927 (+)	Ensembl

RefSeq Acc Id:

NM_001033675 ⟹ NP_001028847

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	47,093,919 - 47,109,614 (+)	NCBI
mRatBN7.2	12	41,433,233 - 41,448,930 (+)	NCBI
Rnor_6.0	12	47,193,964 - 47,209,785 (+)	NCBI
Rnor_5.0	12	48,980,523 - 49,004,882 (+)	NCBI
RGSC_v3.4	12	42,696,383 - 42,720,566 (+)	RGD
Celera	12	43,051,880 - 43,067,622 (+)	NCBI

Sequence:

show sequence

ATGGGCAACTGCGTCAAGTCGCCACTAAGAAACCTCTCGAGAAAGGATAGATCGTTACGACCAG
AGGAGATCGAAGAGCTCCGAGAGGCCTTCCGGGAATTTGACAAGGACAAAGATGGCTACATCAA
CTGCCGGGACCTGGGGAACTGCATGCGCACCATGGGCTACATGCCCACTGAGATGGAACTCATC
GAGCTGTCCCAGCAGATCAACATGAACCTGGGTGGCCACGTGGATTTCGATGACTTTGTGGAAC
TGATGGGCCCTAAACTCCTGGCGGAGACAGCAGATATGATCGGTGTAAAGGAACTGAGAGACGC
CTTTCGGGAGTTTGACACCAACGGTGACGGGGAGATAAGCACGAGCGAGCTGCGAGAGGCCATG
AGGAAGCTCCTGGGTCATCAGGTGGGACACCGGGACATAGAGGAAATTATCCGAGACGTGGACC
TCAATGGAGATGGACGAGTGGACTTCGAAGAGTTTGTCCGGATGATGTCTCGCTGAGGCCGCTG
AGGGGCTCCTCCAGGTCTGCCAACTCCCACAGGCGGGGAGAAGAGCTGAGCTCGCCTCACCCCG
CAGTAGCTGCCGAGAGCCCAGGATGTACTGGCGGATGGGGCCTGCCTGCACCCCGGGGAGGTGC
CCACCCCGGACCCCCACCCCTCTGCACTGTGAAAGACTCACAACTCCTGCAACTGGAAAAGGGG
GCGCCCGCCGGCGAGGAGGCCACAGTGCCAAGCCGGTAGAGGACACGCAAGGCGCCAAGTGCCA
TCTGCCCAGCCGCTGCTGGCTGGGTGGGCCAGGGAGCCCGCCAGCAGACCCCACACAGCATGTC
TGCCCCGAGGGCAGAGCCTTTCAGCGCCCTCCCGATGCCCGTCCCAGCTCGCCTAGCCCTTTGA
TCTCAGAACCAATAAAAAAAACGGAGAATGACAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001033676 ⟹ NP_001028848

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	47,085,292 - 47,109,614 (+)	NCBI
mRatBN7.2	12	41,424,606 - 41,448,930 (+)	NCBI
Rnor_6.0	12	47,185,449 - 47,209,785 (+)	NCBI
Rnor_5.0	12	48,980,523 - 49,004,882 (+)	NCBI
RGSC_v3.4	12	42,696,383 - 42,720,566 (+)	RGD
Celera	12	43,043,462 - 43,067,622 (+)	RGD

Sequence:

show sequence

CCCAGATCCGCAGCGCCGGCCGCCGGGAGCTCGAGGCTCCGGGCGCAGAGGCTGCGCTGTCACA
TGGGCGGCGGCGACGGGGCCGCATTTAAGCGGCCAGGGGACGGCGCCCGCCTGCAGCGCGTCCT
CGGGCTCGGCTCCCGCCGGGCGCCCCGCTCCCTGCCCTCCGGGGGCCCCGCGCCACCCCCGCCG
GGCCATGCGAGCGCGGGCCCCGCCGCGATGAGCTCGCACATCGCCAAGAGCGAGTCCAAGACGT
CGCTGCTCAAGGCGGCGGCGGCGAGCGGGGGCAGCCGGGCTCCCCGCCACAGCTCTGCGCGGGA
CCCCGGGCTGCGTGGCCGCAGGCTGCCCGGTCCCTGCCCCGACTCGCCTGCAACGTGCGGGGAC
CCCAGCTCGCGGAGGCCCCTGTGCCGGCCGGTGCCGCGGGACGAGGGCGCGCGCGGGAGCCGGC
GTGGGCTGCCCCAGGCGCACTGCAGGCCCCGGGAGACGCTACCGCCGGCCCGCGGGCGCGATGG
GGAGGAACGGGGGCTGGCGCCGGCTCTCAGTCTACGGGGCTCCCTGCGATCGCGGGGTCGCGGG
GACCCGGCTCCCGCTGGCACCCCCGAGGCGGACCCGTTCCTCCACCAGCTGCGCCCCATGCTCA
GCTCCGCCTTCGGTCAGGATAGATCGTTACGACCAGAGGAGATCGAAGAGCTCCGAGAGGCCTT
CCGGGAATTTGACAAGGACAAAGATGGCTACATCAACTGCCGGGACCTGGGGAACTGCATGCGC
ACCATGGGCTACATGCCCACTGAGATGGAACTCATCGAGCTGTCCCAGCAGATCAACATGAACC
TGGGTGGCCACGTGGATTTCGATGACTTTGTGGAACTGATGGGCCCTAAACTCCTGGCGGAGAC
AGCAGATATGATCGGTGTAAAGGAACTGAGAGACGCCTTTCGGGAGTTTGACACCAACGGTGAC
GGGGAGATAAGCACGAGCGAGCTGCGAGAGGCCATGAGGAAGCTCCTGGGTCATCAGGTGGGAC
ACCGGGACATAGAGGAAATTATCCGAGACGTGGACCTCAATGGAGATGGACGAGTGGACTTCGA
AGAGTTTGTCCGGATGATGTCTCGCTGAGGCCGCTGAGGGGCTCCTCCAGGTCTGCCAACTCCC
ACAGGCGGGGAGAAGAGCTGAGCTCGCCTCACCCCGCAGTAGCTGCCGAGAGCCCAGGATGTAC
TGGCGGATGGGGCCTGCCTGCACCCCGGGGAGGTGCCCACCCCGGACCCCCACCCCTCTGCACT
GTGAAAGACTCACAACTCCTGCAACTGGAAAAGGGGGCGCCCGCCGGCGAGGAGGCCACAGTGC
CAAGCCGGTAGAGGACACGCAAGGCGCCAAGTGCCATCTGCCCAGCCGCTGCTGGCTGGGTGGG
CCAGGGAGCCCGCCAGCAGACCCCACACAGCATGTCTGCCCCGAGGGCAGAGCCTTTCAGCGCC
CTCCCGATGCCCGTCCCAGCTCGCCTAGCCCTTTGATCTCAGAACCAATAAAAAAAACGGAGAA
TGACAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_133529 ⟹ NP_598213

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	47,093,919 - 47,109,614 (+)	NCBI
mRatBN7.2	12	41,433,233 - 41,448,930 (+)	NCBI
Rnor_6.0	12	47,193,964 - 47,209,785 (+)	NCBI
Rnor_5.0	12	48,980,523 - 49,004,882 (+)	NCBI
RGSC_v3.4	12	42,696,383 - 42,720,566 (+)	RGD
Celera	12	43,051,880 - 43,067,622 (+)	NCBI

Sequence:

show sequence

ATGGGCAACTGCGTCAAGTCGCCACTAAGAAACCTCTCGAGAAAGATGCGCCAGGAGGAGAAGA
CCAGCTACATGGCGGTGCAGACAAGTGAGGATGGGCTGGCGGATGGCGGTGAGCTCCCTGGACC
ACTCATGATGCTGGCCCAGAACTGTGCGGTCATGCACAACCTGCTGGGTCCCGCCTGCATCTTT
CTCCGAAAGGGTTTTGCCGAGAACAGACAACCTGATAGATCGTTACGACCAGAGGAGATCGAAG
AGCTCCGAGAGGCCTTCCGGGAATTTGACAAGGACAAAGATGGCTACATCAACTGCCGGGACCT
GGGGAACTGCATGCGCACCATGGGCTACATGCCCACTGAGATGGAACTCATCGAGCTGTCCCAG
CAGATCAACATGAACCTGGGTGGCCACGTGGATTTCGATGACTTTGTGGAACTGATGGGCCCTA
AACTCCTGGCGGAGACAGCAGATATGATCGGTGTAAAGGAACTGAGAGACGCCTTTCGGGAGTT
TGACACCAACGGTGACGGGGAGATAAGCACGAGCGAGCTGCGAGAGGCCATGAGGAAGCTCCTG
GGTCATCAGGTGGGACACCGGGACATAGAGGAAATTATCCGAGACGTGGACCTCAATGGAGATG
GACGAGTGGACTTCGAAGAGTTTGTCCGGATGATGTCTCGCTGAGGCCGCTGAGGGGCTCCTCC
AGGTCTGCCAACTCCCACAGGCGGGGAGAAGAGCTGAGCTCGCCTCACCCCGCAGTAGCTGCCG
AGAGCCCAGGATGTACTGGCGGATGGGGCCTGCCTGCACCCCGGGGAGGTGCCCACCCCGGACC
CCCACCCCTCTGCACTGTGAAAGACTCACAACTCCTGCAACTGGAAAAGGGGGCGCCCGCCGGC
GAGGAGGCCACAGTGCCAAGCCGGTAGAGGACACGCAAGGCGCCAAGTGCCATCTGCCCAGCCG
CTGCTGGCTGGGTGGGCCAGGGAGCCCGCCAGCAGACCCCACACAGCATGTCTGCCCCGAGGGC
AGAGCCTTTCAGCGCCCTCCCGATGCCCGTCCCAGCTCGCCTAGCCCTTTGATCTCAGAACCAA
TAAAAAAAACGGAGAATGACAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039089041 ⟹ XP_038944969

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	47,045,914 - 47,109,614 (+)	NCBI
mRatBN7.2	12	41,385,234 - 41,448,930 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001028847	(Get FASTA)	NCBI Sequence Viewer
	NP_001028848	(Get FASTA)	NCBI Sequence Viewer
	NP_598213	(Get FASTA)	NCBI Sequence Viewer
	XP_038944969	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	CAC42417	(Get FASTA)	NCBI Sequence Viewer
	CAC43037	(Get FASTA)	NCBI Sequence Viewer
	CAD20347	(Get FASTA)	NCBI Sequence Viewer
	EDM13901	(Get FASTA)	NCBI Sequence Viewer
	EDM13902	(Get FASTA)	NCBI Sequence Viewer
	EDM13903	(Get FASTA)	NCBI Sequence Viewer
	EDM13904	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000001551
	ENSRNOP00000001552
	ENSRNOP00000001552.3
	ENSRNOP00000033685
	ENSRNOP00000033685.3
GenBank Protein	O88751	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001028848 ⟸ NM_001033676
- Peptide Label:	isoform 3
- UniProtKB:	Q91WZ7 (UniProtKB/Swiss-Prot), Q711K8 (UniProtKB/Swiss-Prot), O88751 (UniProtKB/Swiss-Prot), A0A140TA91 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGGGDGAAFKRPGDGARLQRVLGLGSRRAPRSLPSGGPAPPPPGHASAGPAAMSSHIAKSESKT SLLKAAAASGGSRAPRHSSARDPGLRGRRLPGPCPDSPATCGDPSSRRPLCRPVPRDEGARGSR RGLPQAHCRPRETLPPARGRDGEERGLAPALSLRGSLRSRGRGDPAPAGTPEADPFLHQLRPML SSAFGQDRSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMN LGGHVDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVG HRDIEEIIRDVDLNGDGRVDFEEFVRMMSR hide sequence

RefSeq Acc Id:	NP_598213 ⟸ NM_133529
- Peptide Label:	isoform 1
- UniProtKB:	A6J1W3 (UniProtKB/TrEMBL), A0A8I5YC82 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGNCVKSPLRNLSRKMRQEEKTSYMAVQTSEDGLADGGELPGPLMMLAQNCAVMHNLLGPACIF LRKGFAENRQPDRSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQ QINMNLGGHVDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLL GHQVGHRDIEEIIRDVDLNGDGRVDFEEFVRMMSR hide sequence

RefSeq Acc Id:	NP_001028847 ⟸ NM_001033675
- Peptide Label:	isoform 2
- UniProtKB:	A6J1W4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGNCVKSPLRNLSRKDRSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELI ELSQQINMNLGGHVDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSELREAM RKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEFVRMMSR hide sequence

Ensembl Acc Id:

ENSRNOP00000001552 ⟸ ENSRNOT00000001552

Ensembl Acc Id:

ENSRNOP00000001551 ⟸ ENSRNOT00000001551

Ensembl Acc Id:

ENSRNOP00000033685 ⟸ ENSRNOT00000039281

RefSeq Acc Id:	XP_038944969 ⟸ XM_039089041
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSRNOP00000092742 ⟸ ENSRNOT00000114073

Ensembl Acc Id:

ENSRNOP00000078200 ⟸ ENSRNOT00000101243

Protein Domains

EF-hand

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O88751-F1-model_v2	AlphaFold	O88751	1-298	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620385	AgrOrtholog
BioCyc Gene	G2FUF-18977	BioCyc
Ensembl Genes	ENSRNOG00000001173	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000001551	ENTREZGENE
	ENSRNOT00000001552	ENTREZGENE
	ENSRNOT00000001552.8	UniProtKB/Swiss-Prot
	ENSRNOT00000039281	ENTREZGENE
	ENSRNOT00000039281.5	UniProtKB/Swiss-Prot
Gene3D-CATH	EF-hand	UniProtKB/Swiss-Prot
InterPro	CaBP1/2/4/5	UniProtKB/Swiss-Prot
	EF-hand-dom_pair	UniProtKB/Swiss-Prot
	EF_Hand_1_Ca_BS	UniProtKB/Swiss-Prot
	EF_hand_dom	UniProtKB/Swiss-Prot
KEGG Report	rno:171051	UniProtKB/Swiss-Prot
NCBI Gene	171051	ENTREZGENE
PANTHER	CALCIUM-BINDING PROTEIN 1	UniProtKB/Swiss-Prot
	PTHR45917	UniProtKB/Swiss-Prot
Pfam	EF-hand_7	UniProtKB/Swiss-Prot
PhenoGen	Cabp1	PhenoGen
PROSITE	EF_HAND_1	UniProtKB/Swiss-Prot
	EF_HAND_2	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000001173	RatGTEx
SMART	EFh	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF47473	UniProtKB/Swiss-Prot
UniProt	A0A140TA91	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5YC82	ENTREZGENE
	A0A8I6AH55_RAT	UniProtKB/TrEMBL
	A6J1W2_RAT	UniProtKB/TrEMBL
	A6J1W3	ENTREZGENE, UniProtKB/TrEMBL
	A6J1W4	ENTREZGENE, UniProtKB/TrEMBL
	A6J1W5_RAT	UniProtKB/TrEMBL
	CABP1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q711K8	ENTREZGENE
	Q91WZ7	ENTREZGENE
UniProt Secondary	Q711K8	UniProtKB/Swiss-Prot
	Q91WZ7	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Cabp1	calcium binding protein 1	LOC108353433	uncharacterized LOC108353433	Data merged from RGD:11386491	737654	PROVISIONAL
2016-08-02	LOC108353433	uncharacterized LOC108353433			Symbol and Name status set to provisional	70820	PROVISIONAL
2005-01-20	Cabp1	calcium binding protein 1			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Cabp1	calcium binding protein 1			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_cellular_localization	protein is localized to cytoskeleton in dendrites and postsynaptic densities	632450
gene_expression	mRNA expressed in neurons in cerebral cortex, hippocampus and cerebellum	632450
gene_physical_interaction	Cabp1 inhibition of Ca(v)2.1 channels occurs via Capb1 binding to the CaM-binding domain in the Ca(v)2.1	632449
gene_process	enhances inactivation of voltage-gated Ca(v)2.1 channels	632449
gene_protein	protein masses 36 kDa	632450

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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RGD Manual Annotations