Ecm1 (extracellular matrix protein 1)

Advanced Search (OLGA)

Gene: Ecm1 (extracellular matrix protein 1) Rattus norvegicus

Analyze

Symbol:

Ecm1

Name:

extracellular matrix protein 1

RGD ID:

620357

Description:

Predicted to enable interleukin-2 receptor binding activity and protease binding activity. Predicted to be involved in several processes, including negative regulation of bone mineralization; positive regulation of canonical NF-kappaB signal transduction; and positive regulation of endothelial cell proliferation. Predicted to act upstream of or within several processes, including regulation of T cell migration; regulation of type 2 immune response; and skeletal system development. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Human ortholog(s) of this gene implicated in lipoid proteinosis. Orthologous to human ECM1 (extracellular matrix protein 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

secretory component p85

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ECM1 (extracellular matrix protein 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Ecm1 (extracellular matrix protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ecm1 (extracellular matrix protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ECM1 (extracellular matrix protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ECM1 (extracellular matrix protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ecm1 (extracellular matrix protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ECM1 (extracellular matrix protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ECM1 (extracellular matrix protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ecm1 (extracellular matrix protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Ecm1 (extracellular matrix protein 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ECM1 (extracellular matrix protein 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ecm1b (extracellular matrix protein 1b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	ecm1a (extracellular matrix protein 1a)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	185,976,439 - 185,981,656 (-)	NCBI		GRCr8
mRatBN7.2	2	183,287,491 - 183,292,729 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	183,287,322 - 183,292,671 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	190,952,324 - 190,957,491 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	188,747,934 - 188,753,625 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	183,584,856 - 183,590,023 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	197,855,468 - 197,860,973 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	197,855,460 - 197,860,699 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	217,345,268 - 217,350,509 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	190,525,156 - 190,530,323 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	190,489,759 - 190,489,956 (-)	NCBI
Celera	2	175,817,503 - 175,822,670 (-)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

hepatocellular carcinoma (ISO)

immunodeficiency 42 (ISO)

lipoid proteinosis (ISO)

MHC class II deficiency (ISO)

parathyroid carcinoma (ISO)

severe congenital neutropenia 3 (ISO)

severe congenital neutropenia 5 (ISO)

Spontaneous Abortions (ISO)

Stomach Neoplasms (ISO)

ulcerative colitis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

(S)-nicotine (ISO)

1,2-dibromoethane (ISO)

1,2-dimethylhydrazine (ISO)

1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (ISO)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

2-hydroxypropanoic acid (ISO)

2-nitrotoluene (ISO)

2-palmitoylglycerol (ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3-chloropropane-1,2-diol (EXP)

3-methylcholanthrene (ISO)

3-Nitrobenzanthrone (ISO)

4,4'-diaminodiphenylmethane (EXP)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

acetamide (EXP)

acrylamide (EXP)

actinomycin D (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

aluminium atom (ISO)

aluminium(0) (ISO)

ammonium chloride (EXP)

aristolochic acid A (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

benzoates (ISO)

beta-lapachone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

butanal (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

calcitriol (ISO)

camptothecin (ISO)

carbon nanotube (ISO)

chrysene (ISO)

cisplatin (ISO)

copper(II) chloride (ISO)

Cuprizon (EXP)

deoxynivalenol (ISO)

diarsenic trioxide (ISO)

dibenz[a,h]anthracene (ISO)

Dibutyl phosphate (ISO)

diclofenac (ISO)

diethylstilbestrol (EXP)

doxorubicin (ISO)

ethanol (ISO)

fenthion (ISO)

fipronil (EXP)

flutamide (EXP)

folic acid (ISO)

folpet (ISO)

glycidol (ISO)

inulin (ISO)

isoprenaline (ISO)

ivermectin (ISO)

lead diacetate (ISO)

leflunomide (EXP)

methidathion (ISO)

methyl carbamate (ISO)

mono(2-ethylhexyl) phthalate (ISO)

N-nitrosodiethylamine (ISO)

nefazodone (EXP)

nickel sulfate (ISO)

nicotine (ISO)

Nutlin-3 (ISO)

ozone (ISO)

paclitaxel (ISO)

paracetamol (EXP,ISO)

pentachlorophenol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP)

phenethyl isothiocyanate (EXP)

phenobarbital (ISO)

phenylephrine (EXP)

pirinixic acid (ISO)

potassium chromate (ISO)

potassium dichromate (ISO)

progesterone (ISO)

propanal (ISO)

rac-lactic acid (ISO)

rotenone (EXP)

silicon dioxide (EXP,ISO)

sodium arsenite (ISO)

sodium dichromate (ISO)

Soman (EXP)

sunitinib (ISO)

temozolomide (ISO)

tetrachloromethane (ISO)

tetraphene (ISO)

thiram (ISO)

trichloroethene (EXP,ISO)

triphenyl phosphate (EXP)

troglitazone (ISO)

urethane (ISO)

vinclozolin (EXP)

vorinostat (EXP)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

angiogenesis (IEA)

biological_process (ND)

biomineral tissue development (IEA)

chondrocyte development (IEA,ISO)

endochondral bone growth (IEA,ISO)

inflammatory response (IEA,ISO)

negative regulation of bone mineralization (IEA,ISO,ISS)

negative regulation of cytokine-mediated signaling pathway (IEA,ISO)

negative regulation of peptidase activity (ISO,ISS)

ossification (IEA)

positive regulation of angiogenesis (IEA,ISO,ISS)

positive regulation of canonical NF-kappaB signal transduction (ISO)

positive regulation of endothelial cell proliferation (IEA,ISO,ISS)

regulation of bone mineralization (IBA,ISO)

regulation of T cell migration (IEA,ISO)

regulation of transcription by RNA polymerase II (IEA,ISO)

regulation of type 2 immune response (IEA,ISO)

signal transduction (IEA)

Cellular Component

collagen-containing extracellular matrix (IBA,IEA,ISO)

extracellular space (IBA,IEA,ISO)

Molecular Function

interleukin-2 receptor binding (IEA,ISO)

protease binding (IEA,ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Molecular cloning, characterization, and genetic mapping of the cDNA coding for a novel secretory protein of mouse. Demonstration of alternative splicing in skin and cartilage.	Bhalerao J, etal., J Biol Chem 1995 Jul 7;270(27):16385-94.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Lipoid proteinosis maps to 1q21 and is caused by mutations in the extracellular matrix protein 1 gene (ECM1).	Hamada T, etal., Hum Mol Genet 2002 Apr 1;11(7):833-40.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
7.	GOA pipeline	RGD automated data pipeline
8.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:11165938	PMID:11292659	PMID:12477932	PMID:12604605	PMID:12761501	PMID:15489334	PMID:16512877	PMID:19199708	PMID:19275936	PMID:20138147	PMID:20870722	PMID:21217760
PMID:23376485	PMID:24006456	PMID:27068509

Genomics

Comparative Map Data

Ecm1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	185,976,439 - 185,981,656 (-)	NCBI		GRCr8
mRatBN7.2	2	183,287,491 - 183,292,729 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	183,287,322 - 183,292,671 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	190,952,324 - 190,957,491 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	188,747,934 - 188,753,625 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	183,584,856 - 183,590,023 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	197,855,468 - 197,860,973 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	197,855,460 - 197,860,699 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	217,345,268 - 217,350,509 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	190,525,156 - 190,530,323 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	190,489,759 - 190,489,956 (-)	NCBI
Celera	2	175,817,503 - 175,822,670 (-)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

ECM1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	150,508,109 - 150,513,789 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	150,508,062 - 150,513,789 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	150,480,585 - 150,486,265 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	148,747,207 - 148,752,660 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	123,596,250 - 123,602,028 (+)	NCBI		Celera
Cytogenetic Map	1	q21.2	NCBI
HuRef	1	121,858,654 - 121,864,432 (+)	NCBI		HuRef
CHM1_1	1	151,876,297 - 151,882,073 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	149,632,949 - 149,638,627 (+)	NCBI		T2T-CHM13v2.0

Ecm1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	95,641,459 - 95,646,880 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	95,641,459 - 95,646,881 (-)	Ensembl		GRCm39 Ensembl
GRCm38	3	95,734,147 - 95,739,876 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	95,734,147 - 95,739,569 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	95,538,071 - 95,543,492 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	95,819,554 - 95,824,967 (-)	NCBI		MGSCv36	mm8
Celera	3	97,167,107 - 97,172,528 (-)	NCBI		Celera
Cytogenetic Map	3	F2.1	NCBI
cM Map	3	40.91	NCBI

Ecm1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955413	290,363 - 299,130 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955413	293,295 - 299,293 (-)	NCBI	ChiLan1.0	ChiLan1.0

ECM1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	99,324,741 - 99,330,326 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	99,069,972 - 99,084,160 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	125,853,337 - 125,858,904 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	129,502,041 - 129,507,819 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	129,502,041 - 129,507,819 (+)	Ensembl	panpan1.1		panPan2

ECM1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	59,696,125 - 59,701,990 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	59,696,477 - 59,701,744 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	59,142,307 - 59,148,147 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	60,711,672 - 60,717,511 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	60,697,493 - 60,717,511 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	59,542,109 - 59,547,950 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	59,625,886 - 59,631,725 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	60,353,552 - 60,359,392 (+)	NCBI		UU_Cfam_GSD_1.0

Ecm1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	21,720,545 - 21,726,229 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936580	750,736 - 756,771 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936580	750,423 - 756,765 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ECM1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	98,615,778 - 98,621,836 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	98,615,776 - 98,633,081 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	107,904,906 - 107,909,543 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ECM1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Vero_WHO_p1.0	NW_023666038	12,777,257 - 12,783,212 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ecm1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624772	18,233,727 - 18,240,601 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624772	18,234,537 - 18,239,896 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ecm1
29 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	40
Count of miRNA genes:	39
Interacting mature miRNAs:	40
Transcripts:	ENSRNOT00000028740
Prediction methods:	Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358356	Srcrt1	Stress Responsive Cort QTL1	3.66		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	2	161699179	222436696	Rat
1578648	Bss11	Bone structure and strength QTL 11	4.7		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	2	114837527	211674221	Rat
1331734	Bp204	Blood pressure QTL 204	3.61192		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	168358098	223265385	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66118463	226797303	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	81754530	227146641	Rat
1298076	Bp166	Blood pressure QTL 166		0.0009	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	136445150	202447032	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	18960362	228801039	Rat
152025245	Scl81	Serum cholesterol level QTL 81	3.49		blood cholesterol amount (VT:0000180)		2	122609194	206936711	Rat
70162	Bp63	Blood pressure QTL 63	5.64		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	2	169745596	214745596	Rat
1554319	Bmd2	Bone mineral density QTL 2	13.4	0.0001	lumbar vertebra area (VT:0010570)	lumbar vertebra cross-sectional area (CMO:0001689)	2	114837675	212549332	Rat
12879836	Kidm61	Kidney mass QTL 61		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	152413072	185122374	Rat
1581569	Uae32	Urinary albumin excretion QTL 32		0.0001	urine protein amount (VT:0005160)	urine albumin excretion rate (CMO:0000757)	2	78665619	219826953	Rat
10043136	Iddm54	Insulin dependent diabetes mellitus QTL 54	3.4	0.0001	blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	2	143657411	190602963	Rat
12879837	Am2	Aortic mass QTL 2		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	2	152413072	185122374	Rat
1302793	Bw16	Body weight QTL 16	5	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	2	157142209	202446871	Rat
12879838	Cm86	Cardiac mass QTL 86		0.002	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	152413072	185122374	Rat
61467	Bp14	Blood pressure QTL 14	2.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	43154682	202446871	Rat
12879839	Cm85	Cardiac mass QTL 85		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	2	152413072	185122374	Rat
61469	Bp16	Blood pressure QTL 16	5.64		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	2	169745596	214745596	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	2	135552573	202446871	Rat
1549833	Bp257	Blood pressure QTL 257		0.003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	168354880	185122374	Rat
1358900	Bw48	Body weight QTL 48	4.88		body mass (VT:0001259)	body weight (CMO:0000012)	2	157142078	211086598	Rat
1359030	Bp277	Blood pressure QTL 277			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	114837527	185876470	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	56043031	202447032	Rat
12879840	Bw179	Body weight QTL 179		0.005	body mass (VT:0001259)	body weight (CMO:0000012)	2	152413072	185122374	Rat
1581502	Esta3	Estrogen-induced thymic atrophy QTL 3			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	2	136916935	189599348	Rat
9589044	Scfw1	Subcutaneous fat weight QTL 1	5.8	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	2	182171407	227171407	Rat
8694435	Bw166	Body weight QTL 166	14.08	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	2	182171407	227171407	Rat
1359032	Hrtrt18	Heart rate QTL 18			heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	2	157142078	192625452	Rat
2301966	Bp322	Blood pressure QTL 322	3.58		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	150540301	202447032	Rat
1298080	Bp163	Blood pressure QTL 163		0.02	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66118275	202447032	Rat
8662832	Vetf7	Vascular elastic tissue fragility QTL 7	3.5		aorta elastin amount (VT:0003905)	aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)	2	81689826	221035911	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
8694194	Abfw1	Abdominal fat weight QTL 1	11.7	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	2	182171407	227171407	Rat
1641891	Alcrsp17	Alcohol response QTL 17			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	149559561	249053267	Rat
1359022	Ppulsi1	Prepulse inhibition QTL 1	3.63		prepulse inhibition trait (VT:0003088)	acoustic startle response measurement (CMO:0001519)	2	136916935	213594495	Rat
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	78665619	249053267	Rat
2300189	Bmd48	Bone mineral density QTL 48	5.8	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	2	179335906	224335906	Rat
61374	Edpm2	Estrogen-dependent pituitary mass QTL 2	4.42	0.86	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	76539322	202447032	Rat
8662843	Vetf9	Vascular elastic tissue fragility QTL 9	2.05		thoracic aorta molecular composition trait (VT:0010568)	aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)	2	157142078	226277316	Rat
631501	Bp101	Blood pressure QTL 101	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	150341684	202446871	Rat
2307174	Activ3	Activity QTL 3	4.83	0.000058	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	2	168594495	213594495	Rat
1331794	Bp202	Blood pressure QTL 202	3.66819		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	141194931	223265385	Rat
71113	Cari2	Carrageenan-induced inflammation QTL 2	2.7	0.009	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	2	141596551	202447032	Rat
1331805	Cm29	Cardiac mass QTL 29	3.50746		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	2	141194931	223265385	Rat
1598805	Memor8	Memory QTL 8	3		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	2	150341585	189039377	Rat
634308	Sach6	Saccharin preference QTL 6	4.9		taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	2	112456140	212696837	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
724568	Uae13	Urinary albumin excretion QTL 13	4.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	2	143157029	210020885	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
1300165	Rf9	Renal function QTL 9	3.28		kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	2	133914684	202447032	Rat
61401	Niddm2	Non-insulin dependent diabetes mellitus QTL 2	4.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	144599348	189599348	Rat
631507	Bp105	Blood pressure QTL 105		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	112456140	212696837	Rat
1641925	Alcrsp2	Alcohol response QTL 2			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	149559561	221167075	Rat
1354609	Niddm62	Non-insulin dependent diabetes mellitus QTL 62	4.72	0.000006	insulin secretion trait (VT:0003564)	plasma insulin level (CMO:0000342)	2	150540301	202447032	Rat
1598833	Bp295	Blood pressure QTL 295	3.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	147798556	192798556	Rat
61417	Cia10	Collagen induced arthritis QTL 10	3.4		joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	2	179946951	224946951	Rat
1354622	Kidm16	Kidney mass QTL 16	3		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	2	81754530	222436696	Rat
631266	Bp132	Blood pressure QTL 132		0.0005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	46123260	202447032	Rat
631522	Bp74	Blood pressure QTL 74		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	172710921	184114403	Rat
8694383	Bw158	Body weight QTL 158	7.69	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	2	182171407	227171407	Rat
7488927	Bp365	Blood pressure QTL 365		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	162765032	207765032	Rat
1598838	Bp290	Blood pressure QTL 290	1.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	166539266	211539266	Rat
7488925	Bp364	Blood pressure QTL 364		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	160564068	205564068	Rat
2306901	Bp337	Blood pressure QTL 337		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	164073756	227146641	Rat
1354605	Rf48	Renal function QTL 48	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	2	74786664	206665859	Rat
6903312	Bw112	Body weight QTL 112	3.2	0.0013	body mass (VT:0001259)	body weight (CMO:0000012)	2	143657569	184114274	Rat
1354601	Slep1	Serum leptin concentration QTL 1	5.39		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	2	43171017	184114403	Rat
2293084	Iddm26	Insulin dependent diabetes mellitus QTL 26	2.9		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	174930955	213594495	Rat

Markers in Region

Ecm1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	183,292,489 - 183,292,676 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	197,860,466 - 197,860,652	NCBI	Rnor6.0
Rnor_5.0	2	217,350,266 - 217,350,452	UniSTS	Rnor5.0
RGSC_v3.4	2	190,530,154 - 190,530,340	UniSTS	RGSC3.4
Celera	2	175,822,501 - 175,822,687	UniSTS
Cytogenetic Map	2	q34	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_053882	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006232942	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101580	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281170	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC141102	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC085879	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U42581	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000028740 ⟹ ENSRNOP00000028740

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	183,287,322 - 183,292,671 (-)	Ensembl
Rnor_6.0 Ensembl	2	197,855,460 - 197,860,699 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000105287 ⟹ ENSRNOP00000085798

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	183,287,492 - 183,291,472 (-)	Ensembl

RefSeq Acc Id:

NM_053882 ⟹ NP_446334

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	185,976,439 - 185,981,606 (-)	NCBI
mRatBN7.2	2	183,287,491 - 183,292,659 (-)	NCBI
Rnor_6.0	2	197,855,468 - 197,860,635 (-)	NCBI
Rnor_5.0	2	217,345,268 - 217,350,509 (-)	NCBI
RGSC_v3.4	2	190,525,156 - 190,530,323 (-)	RGD
Celera	2	175,817,503 - 175,822,670 (-)	RGD

Sequence:

show sequence

GCAGCAGCCAGAGGAGCAGGCTTGCAGCAAGTGGCCCAGCCCCTTCAGGTCTAGATCTGCCTGT
GACAACTGCTGCTGGGTGACCCGTGACCAGTTCTTACCCCAGGATGGGGACCATACGCAGCTCA
GCCTTGATCTTGGCCTGCTTGGCTCTTGCTTCTGCTGCCTCTGAGGGAGCCTTCAAGGTTTCAG
ACCAGAGAGAGATGAAGCCAGAGCACCTCTTCCAGCACCTCCATGAAGTAGGCTATGCAGCACC
CCCTTCCCCACCACAAACCCGGAGACTCCAAGTTCACCACTCCGAAACTTCTCCGCATGACCCT
CCCCTCTTTGAGGAACAAAAAGAAGTGCAGCCCCCTTCTTCCCCAGAAGACATCCCTGTGTATG
AGGAGGAATGGCTCACTTTCCTAAACCCTAATGTAGGTAAAGTGGATCCTGCTCTCCCTCAAGA
AGCCATCCCCCTGCAGAAAGAGCAGCCCCCTCCTCGAATCCCAATTGAACAGAAGGAAATAGAC
CCACCTGTCCAACATCAGGAGGAGATTGTTCAGTCCCGGCAGAAAGAGGAGAAGCCACCCACCT
TGACGGGCCAGCATCCTCCAGAGCCCCGAACTTGGAATCCAGCCCGTCACTGCCAGCAGGGACG
GAGAGGTATCTGGGGCCACCGGCTGGATGGCTTCCCTCCTGGACGGCCTTCTCCAGACAATCTG
AAGCAGATCTGCCTTCCTGAGCGCCAGCACGTGGTCTATGGCCCCTGGAACCTGCCACAGACTG
GCTACTCTCACCTTAGTCGCCAGGGAGAGGCCCTCAATTTGCTGGAGACCGGATATTCCCGCTG
CTGTCGCTGCCGCAGCGACACAAATCGCCTAGACTGTGTGAAGCTTGTGTGGGAGGACGCAATG
ACCCAGTTCTGTGAGGCTGAATTCTCTGTCAAGACCCGACCCCACCTGTGCTGCAAACAGCGTG
GGGAGGAGCGATTCTCTTGCTTCCAGAAGGAAGCTCCTCGGCCCGACTACCTGCTCCGACCCTG
CCCCATCCACCAGACTGGCATTTCCTCAGGAACCCAACTGCCTTTCCCTCCGGGGTTGCCCACA
CCGGACAATGTCAAAAACATCTGTCTCCTGAGACGCTTCCGCTCCGTGCCGCGCAACCTCCCAG
CTACTGACGCCATCCAGAGGCAGCTGCAGGCTCTGACCCGGCTGGAGACGGAGTTCCAGCGCTG
CTGCCGCCAGGGTCACAACCACACTTGCACATGGAAGGCCTGGGAGGATACCCTGGATGGATAC
TGTGATCGGGAGCTGGCTATAAAGACCCACCCCCACTCGTGCTGCCACTACCCTCCAAGTCCTG
CCCGTGATGAATGTTTTGCCCACCTCGCTCCCTATCCCAACTATGACCGGGATCTCTTGACCGT
TGACCTTAGCCGAGTCACCCCCAACCTCATGGACCATCTCTGTGGAAACGGAAGAGTTCTCAGC
AAGCATAAACAGATCCCTGGCCTGATCCAGAACATGACTGTCCGCTGCTGCGAGCTGCCATACC
CAGAACAGGCCTGCTGTGGTGAGGAGGAGAAACTGGCTTTCATTGAGGATCTCTGTGGTCCCCG
GAGGAACTCCTGGAAAGATCCTGCCCTCTGCTGTACCTTGTCTCCTGGAGATAAACAAGCCAAC
TGCTTCAATACCAACTACCTGAGGAATGTGGCTTTAGTGGCTGGAGACACTGGGAATGCCACTG
GCCTGGGGCAGCAGGGCCCAACTGGGGGAACAAATGTCGGCCCCGCCCCTGGGTCCAAGGAAGA
ATGAGTCACCCTGAGCCTCAGAGGATTAGATGGGGTACCCCGCCCTACTCCACCCTCCTTGAAC
ACTCATTACAATAAATGCCTCTTGGATTTGGCAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006232942 ⟹ XP_006233004

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	185,976,439 - 185,981,656 (-)	NCBI
mRatBN7.2	2	183,287,491 - 183,292,719 (-)	NCBI
Rnor_6.0	2	197,855,468 - 197,860,973 (-)	NCBI
Rnor_5.0	2	217,345,268 - 217,350,509 (-)	NCBI

Sequence:

show sequence

ATCCCCAAGTAAAATTCTTAGTGCCCGTCCCCCCACTTCATTCAGGAGGGTGCCAGATCCCCTC
TCTATAAAGGACAATACGCAGGAGGGAAGCCCAGACACAAGTTAAGGGTGCAGTGCCAACTTGC
TCCGTGGTTCTCTGCATCAGTTCTGAGGGGTCTCATGAGTGTCCCCTCCATCACCTCCACTCTT
CCCAGGCTAAGGAGGCTCCTGGAGGCTGGGAGGCGTGACTGTAAGGGGAGGAGCCGCTGGGACT
GAGTCATGGCAGGAAACAGGAGGGAGGGCGGGAGATAGCATATAAAGAGAGACAGCAGGCCTTG
AAGTTCACAGCGGCAGTAGCAGCAGCCAGAGGAGCAGGCTTGCAGCAAGTGGCCCAGCCCCTTC
AGGTCTAGATCTGCCTGTGACAACTGCTGCTGGGTGACCCGTGACCAGTTCTTACCCCAGGATG
GGGACCATACGCAGCTCAGCCTTGATCTTGGCCTGCTTGGCTCTTGCTTCTGCTGCCTCTGAGG
GAGCCTTCAAGGTTTCAGACCAGAGAGAGATGAAGCCAGAGCACCTCTTCCAGCACCTCCATGA
AGGCTATGCAGCACCCCCTTCCCCACCACAAACCCGGAGACTCCAAGTTCACCACTCCGAAACT
TCTCCGCATGACCCTCCCCTCTTTGAGGAACAAAAAGAAGTGCAGCCCCCTTCTTCCCCAGAAG
ACATCCCTGTGTATGAGGAGGAATGGCTCACTTTCCTAAACCCTAATGTAGGTAAAGTGGATCC
TGCTCTCCCTCAAGAAGCCATCCCCCTGCAGAAAGAGCAGCCCCCTCCTCGAATCCCAATTGAA
CAGAAGGAAATAGACCCACCTGTCCAACATCAGGAGGAGATTGTTCAGTCCCGGCAGAAAGAGG
AGAAGCCACCCACCTTGACGGGCCAGCATCCTCCAGAGCCCCGAACTTGGAATCCAGCCCGTCA
CTGCCAGCAGGGACGGAGAGGTATCTGGGGCCACCGGCTGGATGGCTTCCCTCCTGGACGGCCT
TCTCCAGACAATCTGAAGCAGATCTGCCTTCCTGAGCGCCAGCACGTGGTCTATGGCCCCTGGA
ACCTGCCACAGACTGGCTACTCTCACCTTAGTCGCCAGGGAGAGGCCCTCAATTTGCTGGAGAC
CGGATATTCCCGCTGCTGTCGCTGCCGCAGCGACACAAATCGCCTAGACTGTGTGAAGCTTGTG
TGGGAGGACGCAATGACCCAGTTCTGTGAGGCTGAATTCTCTGTCAAGACCCGACCCCACCTGT
GCTGCAAACAGCGTGGGGAGGAGCGATTCTCTTGCTTCCAGAAGGAAGCTCCTCGGCCCGACTA
CCTGCTCCGACCCTGCCCCATCCACCAGACTGGCATTTCCTCAGGAACCCAACTGCCTTTCCCT
CCGGGGTTGCCCACACCGGACAATGTCAAAAACATCTGTCTCCTGAGACGCTTCCGCTCCGTGC
CGCGCAACCTCCCAGCTACTGACGCCATCCAGAGGCAGCTGCAGGCTCTGACCCGGCTGGAGAC
GGAGTTCCAGCGCTGCTGCCGCCAGGGTCACAACCACACTTGCACATGGAAGGCCTGGGAGGAT
ACCCTGGATGGATACTGTGATCGGGAGCTGGCTATAAAGACCCACCCCCACTCGTGCTGCCACT
ACCCTCCAAGTCCTGCCCGTGATGAATGTTTTGCCCACCTCGCTCCCTATCCCAACTATGACCG
GGATCTCTTGACCGTTGACCTTAGCCGAGTCACCCCCAACCTCATGGACCATCTCTGTGGAAAC
GGAAGAGTTCTCAGCAAGCATAAACAGATCCCTGGCCTGATCCAGAACATGACTGTCCGCTGCT
GCGAGCTGCCATACCCAGAACAGGCCTGCTGTGGTGAGGAGGAGAAACTGGCTTTCATTGAGGA
TCTCTGTGGTCCCCGGAGGAACTCCTGGAAAGATCCTGCCCTCTGCTGTACCTTGTCTCCTGGA
GATAAACAAGCCAACTGCTTCAATACCAACTACCTGAGGAATGTGGCTTTAGTGGCTGGAGACA
CTGGGAATGCCACTGGCCTGGGGCAGCAGGGCCCAACTGGGGGAACAAATGTCGGCCCCGCCCC
TGGGTCCAAGGAAGAATGAGTCACCCTGAGCCTCAGAGGATTAGATGGGGTACCCCGCCCTACT
CCACCCTCCTTGAACACTCATTACAATAAATGCCTCTTGGATTTGGCA

hide sequence

RefSeq Acc Id:

XM_039101580 ⟹ XP_038957508

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	185,976,439 - 185,981,652 (-)	NCBI
mRatBN7.2	2	183,287,491 - 183,292,718 (-)	NCBI

RefSeq Acc Id:

XM_063281170 ⟹ XP_063137240

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	185,976,439 - 185,981,654 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_446334	(Get FASTA)	NCBI Sequence Viewer
	XP_006233004	(Get FASTA)	NCBI Sequence Viewer
	XP_038957508	(Get FASTA)	NCBI Sequence Viewer
	XP_063137240	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA84385	(Get FASTA)	NCBI Sequence Viewer
	AAH85879	(Get FASTA)	NCBI Sequence Viewer
	EDL85691	(Get FASTA)	NCBI Sequence Viewer
	EDL85692	(Get FASTA)	NCBI Sequence Viewer
	EDL85693	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000028740.4
	ENSRNOP00000085798.1
	ENSRNOP00055045361
	ENSRNOP00060018037
	ENSRNOP00065032963
GenBank Protein	Q62894	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_446334 ⟸ NM_053882
- Peptide Label:	precursor
- UniProtKB:	Q5U2S9 (UniProtKB/Swiss-Prot), Q62894 (UniProtKB/Swiss-Prot), A6K307 (UniProtKB/TrEMBL), A0A8L2QGP4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGTIRSSALILACLALASAASEGAFKVSDQREMKPEHLFQHLHEVGYAAPPSPPQTRRLQVHHS ETSPHDPPLFEEQKEVQPPSSPEDIPVYEEEWLTFLNPNVGKVDPALPQEAIPLQKEQPPPRIP IEQKEIDPPVQHQEEIVQSRQKEEKPPTLTGQHPPEPRTWNPARHCQQGRRGIWGHRLDGFPPG RPSPDNLKQICLPERQHVVYGPWNLPQTGYSHLSRQGEALNLLETGYSRCCRCRSDTNRLDCVK LVWEDAMTQFCEAEFSVKTRPHLCCKQRGEERFSCFQKEAPRPDYLLRPCPIHQTGISSGTQLP FPPGLPTPDNVKNICLLRRFRSVPRNLPATDAIQRQLQALTRLETEFQRCCRQGHNHTCTWKAW EDTLDGYCDRELAIKTHPHSCCHYPPSPARDECFAHLAPYPNYDRDLLTVDLSRVTPNLMDHLC GNGRVLSKHKQIPGLIQNMTVRCCELPYPEQACCGEEEKLAFIEDLCGPRRNSWKDPALCCTLS PGDKQANCFNTNYLRNVALVAGDTGNATGLGQQGPTGGTNVGPAPGSKEE hide sequence

RefSeq Acc Id:	XP_006233004 ⟸ XM_006232942
- Peptide Label:	isoform X1
- UniProtKB:	A0A8L2QGP4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGTIRSSALILACLALASAASEGAFKVSDQREMKPEHLFQHLHEGYAAPPSPPQTRRLQVHHSE TSPHDPPLFEEQKEVQPPSSPEDIPVYEEEWLTFLNPNVGKVDPALPQEAIPLQKEQPPPRIPI EQKEIDPPVQHQEEIVQSRQKEEKPPTLTGQHPPEPRTWNPARHCQQGRRGIWGHRLDGFPPGR PSPDNLKQICLPERQHVVYGPWNLPQTGYSHLSRQGEALNLLETGYSRCCRCRSDTNRLDCVKL VWEDAMTQFCEAEFSVKTRPHLCCKQRGEERFSCFQKEAPRPDYLLRPCPIHQTGISSGTQLPF PPGLPTPDNVKNICLLRRFRSVPRNLPATDAIQRQLQALTRLETEFQRCCRQGHNHTCTWKAWE DTLDGYCDRELAIKTHPHSCCHYPPSPARDECFAHLAPYPNYDRDLLTVDLSRVTPNLMDHLCG NGRVLSKHKQIPGLIQNMTVRCCELPYPEQACCGEEEKLAFIEDLCGPRRNSWKDPALCCTLSP GDKQANCFNTNYLRNVALVAGDTGNATGLGQQGPTGGTNVGPAPGSKEE hide sequence

Ensembl Acc Id:

ENSRNOP00000028740 ⟸ ENSRNOT00000028740

RefSeq Acc Id:	XP_038957508 ⟸ XM_039101580
- Peptide Label:	isoform X2
- UniProtKB:	A0A8L2QGP4 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000085798 ⟸ ENSRNOT00000105287

RefSeq Acc Id:	XP_063137240 ⟸ XM_063281170
- Peptide Label:	isoform X3

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q62894-F1-model_v2	AlphaFold	Q62894	1-562	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691555

Promoter ID:

EPDNEW_R2079

Type:

multiple initiation site

Name:

Ecm1_1

Description:

extracellular matrix protein 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	197,860,647 - 197,860,707	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620357	AgrOrtholog
BioCyc Gene	G2FUF-52076	BioCyc
Ensembl Genes	ENSRNOG00000021166	Ensembl, UniProtKB/TrEMBL
	ENSRNOG00055031669	UniProtKB/Swiss-Prot
	ENSRNOG00060013364	UniProtKB/Swiss-Prot
	ENSRNOG00065023596	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000028740.6	UniProtKB/TrEMBL
	ENSRNOT00000105287.1	UniProtKB/TrEMBL
	ENSRNOT00055054879	UniProtKB/Swiss-Prot
	ENSRNOT00060022793	UniProtKB/Swiss-Prot
	ENSRNOT00065040468	UniProtKB/Swiss-Prot
Gene3D-CATH	1.10.246.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7191762	IMAGE-MGC_LOAD
InterPro	ECM1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Serum_albumin-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:116662	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:94653	IMAGE-MGC_LOAD
NCBI Gene	116662	ENTREZGENE
PANTHER	EXTRACELLULAR MATRIX PROTEIN 1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR16776	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	ECM1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Ecm1	PhenoGen
RatGTEx	ENSRNOG00000021166	RatGTEx
	ENSRNOG00055031669	RatGTEx
	ENSRNOG00060013364	RatGTEx
	ENSRNOG00065023596	RatGTEx
Superfamily-SCOP	SSF48552	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I6A022_RAT	UniProtKB/TrEMBL
	A0A8L2QGP4	ENTREZGENE, UniProtKB/TrEMBL
	A6K307	ENTREZGENE, UniProtKB/TrEMBL
	A6K308_RAT	UniProtKB/TrEMBL
	A6K309_RAT	UniProtKB/TrEMBL
	ECM1_RAT	UniProtKB/Swiss-Prot
	Q5U2S9	ENTREZGENE
	Q62894	ENTREZGENE
UniProt Secondary	Q5U2S9	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-09-10	Ecm1	extracellular matrix protein 1			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Ecm1	extracellular matrix protein 1			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM