Dlgap2 (DLG associated protein 2) - Rat Genome Database

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Gene: Dlgap2 (DLG associated protein 2) Rattus norvegicus
Analyze
Symbol: Dlgap2
Name: DLG associated protein 2
RGD ID: 620224
Description: Enables protein domain specific binding activity. Predicted to be involved in modulation of chemical synaptic transmission. Located in dendritic spine. Orthologous to human DLGAP2 (DLG associated protein 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DAP-2; discs large homolog associated protein 2; discs large homolog-associated protein 2; discs, large (Drosophila) homolog-associated protein 2; disks large-associated protein 2; postsynaptic density 95; PSD-95/SAP90-associated protein-2; PSD-95/SAP90-binding protein 2; SAP90/PSD-95-associated protein 2; SAPAP2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81681,489,059 - 82,198,693 (-)NCBIGRCr8
mRatBN7.21674,786,771 - 75,496,402 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1674,791,509 - 75,496,407 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1680,070,840 - 80,774,723 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01683,524,409 - 84,228,270 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01678,773,458 - 79,476,474 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01679,872,238 - 80,596,977 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1679,872,323 - 79,973,877 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01679,447,602 - 80,163,277 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41679,613,016 - 80,328,220 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11679,613,280 - 80,328,485 (-)NCBI
Celera1672,609,167 - 73,309,082 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Three isoforms of synaptic scaffolding molecule and their characterization. Multimerization between the isoforms and their interaction with N-methyl-D-aspartate receptors and SAP90/PSD-95-associated protein. Hirao K, etal., J Biol Chem 2000 Jan 28;275(4):2966-72.
3. Differential expression of isoforms of PSD-95 binding protein (GKAP/SAPAP1) during rat brain development. Kawashima N, etal., FEBS Lett 1997 Dec 1;418(3):301-4.
4. SNX26, a GTPase-activating protein for Cdc42, interacts with PSD-95 protein and is involved in activity-dependent dendritic spine formation in mature neurons. Kim Y, etal., J Biol Chem. 2013 Oct 11;288(41):29453-66. doi: 10.1074/jbc.M113.468801. Epub 2013 Sep 3.
5. Sharpin, a novel postsynaptic density protein that directly interacts with the shank family of proteins. Lim S, etal., Mol Cell Neurosci 2001 Feb;17(2):385-97.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. CRIPT, a novel postsynaptic protein that binds to the third PDZ domain of PSD-95/SAP90. Niethammer M, etal., Neuron 1998 Apr;20(4):693-707.
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. DAP-1, a novel protein that interacts with the guanylate kinase-like domains of hDLG and PSD-95. Satoh K, etal., Genes Cells. 1997 Jun;2(6):415-24.
13. SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density. Takeuchi M, etal., J Biol Chem 1997 May 2;272(18):11943-51.
14. MAGUIN, a novel neuronal membrane-associated guanylate kinase-interacting protein. Yao I, etal., J Biol Chem 1999 Apr 23;274(17):11889-96.
15. Eye opening induces a rapid dendritic localization of PSD-95 in central visual neurons. Yoshii A, etal., Proc Natl Acad Sci U S A 2003 Feb 4;100(3):1334-9.
Additional References at PubMed
PMID:7569905   PMID:9786987   PMID:12675619   PMID:16332687   PMID:16598705   PMID:16914526   PMID:16990791   PMID:19793403   PMID:21865455   PMID:22871113   PMID:24585759   PMID:25071926  
PMID:29476059   PMID:34818135  


Genomics

Comparative Map Data
Dlgap2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81681,489,059 - 82,198,693 (-)NCBIGRCr8
mRatBN7.21674,786,771 - 75,496,402 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1674,791,509 - 75,496,407 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1680,070,840 - 80,774,723 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01683,524,409 - 84,228,270 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01678,773,458 - 79,476,474 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01679,872,238 - 80,596,977 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1679,872,323 - 79,973,877 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01679,447,602 - 80,163,277 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41679,613,016 - 80,328,220 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11679,613,280 - 80,328,485 (-)NCBI
Celera1672,609,167 - 73,309,082 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
DLGAP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388737,628 - 1,708,476 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8737,628 - 1,708,476 (+)EnsemblGRCh38hg38GRCh38
GRCh378687,628 - 1,656,642 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3681,436,976 - 1,644,049 (+)NCBINCBI36Build 36hg18NCBI36
Build 3481,436,975 - 1,644,047NCBI
Celera81,394,347 - 1,599,502 (+)NCBICelera
Cytogenetic Map8p23.3NCBI
HuRef81,267,051 - 1,471,555 (+)NCBIHuRef
CHM1_181,442,343 - 1,656,072 (+)NCBICHM1_1
T2T-CHM13v2.08529,208 - 1,487,141 (+)NCBIT2T-CHM13v2.0
Dlgap2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39814,145,793 - 14,903,426 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl814,145,865 - 14,897,680 (+)EnsemblGRCm39 Ensembl
GRCm38814,095,776 - 14,853,426 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl814,095,865 - 14,847,680 (+)EnsemblGRCm38mm10GRCm38
MGSCv37814,095,875 - 14,847,687 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36814,095,852 - 14,847,657 (+)NCBIMGSCv36mm8
Celera814,255,751 - 15,011,554 (+)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map86.51NCBI
Dlgap2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540357,964,105 - 58,421,392 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540357,965,571 - 58,493,946 (-)NCBIChiLan1.0ChiLan1.0
DLGAP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2715,420,502 - 16,422,184 (+)NCBINHGRI_mPanPan1-v2
Mhudiblu_PPA_v085,661,423 - 6,661,559 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18861,982 - 1,603,678 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8759,261 - 1,596,858 (+)Ensemblpanpan1.1panPan2
DLGAP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13730,214,555 - 30,842,384 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3730,214,947 - 30,835,991 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3730,915,053 - 31,607,732 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03730,178,682 - 30,869,610 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3730,178,589 - 30,869,356 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13730,145,661 - 30,779,636 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03730,020,698 - 30,718,335 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03730,034,453 - 30,727,882 (+)NCBIUU_Cfam_GSD_1.0
Dlgap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404943586,035 - 958,050 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936615316,449 - 956,192 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936615837,217 - 932,487 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DLGAP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1532,600,234 - 33,267,312 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11532,600,188 - 33,267,319 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21537,078,011 - 37,746,896 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DLGAP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.181,304,284 - 1,380,010 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605442,150,269 - 43,266,697 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dlgap2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624861419,558 - 939,456 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624861419,427 - 939,553 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dlgap2
4917 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:53
Count of miRNA genes:46
Interacting mature miRNAs:50
Transcripts:ENSRNOT00000057845
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
70215Niddm29Non-insulin dependent diabetes mellitus QTL 293.54blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)161900443575226532Rat
1578768Stresp22Stress response QTL 222.8thymus mass (VT:0004954)thymus wet weight (CMO:0000855)163528887080288870Rat
2293690Bss45Bone structure and strength QTL 455.130.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)163775215682752156Rat
2300163Bmd64Bone mineral density QTL 645.30.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)163775215682752156Rat
7205510Activ5Activity QTL 53.780.00028locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)164239634584729064Rat
8694429Bw164Body weight QTL 16450.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)165272646484729064Rat
8694364Abfw7Abdominal fat weight QTL 712.220.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)165272646484729064Rat
7411648Foco22Food consumption QTL 22150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)165272646484729064Rat
631525Pia14Pristane induced arthritis QTL 144.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)165571108783402471Rat
1298527Arunc2Aerobic running capacity QTL 22.9exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)166853271675029966Rat

Markers in Region
D16Rat48  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21675,029,810 - 75,029,966 (+)MAPPERmRatBN7.2
Rnor_6.01680,115,641 - 80,115,794NCBIRnor6.0
Rnor_5.01679,690,255 - 79,690,408UniSTSRnor5.0
RGSC_v3.41679,850,041 - 79,850,195RGDRGSC3.4
RGSC_v3.41679,850,042 - 79,850,195UniSTSRGSC3.4
RGSC_v3.11679,850,307 - 79,850,460RGD
Celera1672,845,336 - 72,845,489UniSTS
RH 3.4 Map16730.4UniSTS
RH 3.4 Map16730.4RGD
SHRSP x BN Map1645.5099UniSTS
SHRSP x BN Map1645.5099RGD
Cytogenetic Map16q12.5UniSTS
D16Rat15  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21675,226,397 - 75,226,532 (+)MAPPERmRatBN7.2
Rnor_6.01680,316,290 - 80,316,424NCBIRnor6.0
Rnor_5.01679,886,331 - 79,886,465UniSTSRnor5.0
RGSC_v3.41680,046,992 - 80,047,126UniSTSRGSC3.4
RGSC_v3.41680,046,991 - 80,047,126RGDRGSC3.4
RGSC_v3.11680,047,257 - 80,047,391RGD
Celera1673,041,297 - 73,041,431UniSTS
RH 3.4 Map16723.1RGD
RH 3.4 Map16723.1UniSTS
RH 2.0 Map16841.4RGD
SHRSP x BN Map1645.5RGD
FHH x ACI Map1642.3699RGD
Cytogenetic Map16q12.5UniSTS
D16Got89  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21675,447,112 - 75,447,243 (+)MAPPERmRatBN7.2
Rnor_6.01680,548,024 - 80,548,154NCBIRnor6.0
Rnor_5.01680,114,125 - 80,114,255UniSTSRnor5.0
RGSC_v3.41680,279,180 - 80,279,311RGDRGSC3.4
RGSC_v3.41680,279,181 - 80,279,311UniSTSRGSC3.4
RGSC_v3.11680,279,446 - 80,279,576RGD
Celera1673,260,873 - 73,261,003UniSTS
RH 3.4 Map16737.6UniSTS
RH 3.4 Map16737.6RGD
RH 2.0 Map16874.8RGD
Cytogenetic Map16q12.5UniSTS
D16Got84  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21675,217,693 - 75,217,952 (+)MAPPERmRatBN7.2
Rnor_6.01680,307,586 - 80,307,844NCBIRnor6.0
Rnor_5.01679,877,627 - 79,877,885UniSTSRnor5.0
RGSC_v3.41680,038,257 - 80,038,753RGDRGSC3.4
RGSC_v3.41680,038,288 - 80,038,546UniSTSRGSC3.4
RGSC_v3.11680,038,553 - 80,038,811RGD
Celera1673,032,593 - 73,032,851UniSTS
RH 3.4 Map16727.8RGD
RH 3.4 Map16727.8UniSTS
Cytogenetic Map16q12.5UniSTS
32.MMHAP64FRC11.seq  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21675,208,366 - 75,208,553 (+)MAPPERmRatBN7.2
Rnor_6.01680,298,259 - 80,298,445NCBIRnor6.0
Rnor_5.01679,868,300 - 79,868,486UniSTSRnor5.0
RGSC_v3.41680,028,961 - 80,029,147UniSTSRGSC3.4
Celera1673,023,266 - 73,023,452UniSTS
Cytogenetic Map16q12.5UniSTS
RH144459  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21675,112,623 - 75,112,789 (+)MAPPERmRatBN7.2
Rnor_6.01680,201,326 - 80,201,491NCBIRnor6.0
Rnor_5.01679,772,884 - 79,773,049UniSTSRnor5.0
RGSC_v3.41679,932,810 - 79,932,975UniSTSRGSC3.4
Celera1672,927,605 - 72,927,770UniSTS
RH 3.4 Map16729.4UniSTS
Cytogenetic Map16q12.5UniSTS
RH138324  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21675,001,743 - 75,001,880 (+)MAPPERmRatBN7.2
Rnor_6.01680,087,458 - 80,087,594NCBIRnor6.0
Rnor_5.01679,662,072 - 79,662,208UniSTSRnor5.0
RGSC_v3.41679,821,978 - 79,822,114UniSTSRGSC3.4
Celera1672,817,272 - 72,817,408UniSTS
Cytogenetic Map16q12.5UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system appendage
High
Medium 21
Low 5 49 14
Below cutoff 2 13 5 7 5 2 2 4 23 6 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000057845   ⟹   ENSRNOP00000054654
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1674,791,509 - 74,924,781 (-)Ensembl
Rnor_6.0 Ensembl1679,872,514 - 79,973,735 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000086896   ⟹   ENSRNOP00000069108
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1674,791,509 - 75,496,249 (-)Ensembl
Rnor_6.0 Ensembl1679,872,323 - 79,973,877 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000107787   ⟹   ENSRNOP00000086979
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1674,791,509 - 75,496,407 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000117188   ⟹   ENSRNOP00000080482
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1674,791,509 - 75,496,407 (-)Ensembl
RefSeq Acc Id: NM_053901   ⟹   NP_446353
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81681,495,374 - 82,198,622 (-)NCBI
mRatBN7.21674,793,098 - 75,496,386 (-)NCBI
Rnor_6.01679,872,238 - 80,596,977 (-)NCBI
Rnor_5.01679,447,602 - 80,163,277 (-)NCBI
RGSC_v3.41679,613,016 - 80,328,220 (-)RGD
Celera1672,609,167 - 73,309,082 (-)RGD
Sequence:
RefSeq Acc Id: XM_039094154   ⟹   XP_038950082
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81681,489,059 - 82,198,693 (-)NCBI
mRatBN7.21674,786,771 - 75,496,402 (-)NCBI
RefSeq Acc Id: XM_039094156   ⟹   XP_038950084
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81681,489,059 - 81,941,987 (-)NCBI
mRatBN7.21674,793,374 - 75,237,922 (-)NCBI
RefSeq Acc Id: XM_039094157   ⟹   XP_038950085
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81681,489,059 - 82,198,637 (-)NCBI
mRatBN7.21674,786,771 - 75,496,402 (-)NCBI
RefSeq Acc Id: XM_063275039   ⟹   XP_063131109
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81681,489,059 - 81,868,143 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_446353   ⟸   NM_053901
- UniProtKB: P97837 (UniProtKB/Swiss-Prot),   A0A8I5ZQT2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000054654   ⟸   ENSRNOT00000057845
RefSeq Acc Id: ENSRNOP00000069108   ⟸   ENSRNOT00000086896
RefSeq Acc Id: XP_038950085   ⟸   XM_039094157
- Peptide Label: isoform X4
- UniProtKB: A0A8I6A4U6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038950082   ⟸   XM_039094154
- Peptide Label: isoform X1
- UniProtKB: P97837 (UniProtKB/Swiss-Prot),   A0A0G2JUI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038950084   ⟸   XM_039094156
- Peptide Label: isoform X3
- UniProtKB: A6IWE1 (UniProtKB/TrEMBL),   F1LSL6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000086979   ⟸   ENSRNOT00000107787
RefSeq Acc Id: ENSRNOP00000080482   ⟸   ENSRNOT00000117188
RefSeq Acc Id: XP_063131109   ⟸   XM_063275039
- Peptide Label: isoform X2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97837-F1-model_v2 AlphaFold P97837 1-1059 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620224 AgrOrtholog
BioCyc Gene G2FUF-10745 BioCyc
Ensembl Genes ENSRNOG00000012573 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000057845.3 UniProtKB/TrEMBL
  ENSRNOT00000086896.2 UniProtKB/TrEMBL
  ENSRNOT00000107787.1 UniProtKB/TrEMBL
  ENSRNOT00000117188 ENTREZGENE
  ENSRNOT00000117188.1 UniProtKB/TrEMBL
InterPro SAPAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:116681 UniProtKB/Swiss-Prot
NCBI Gene 116681 ENTREZGENE
PANTHER PTHR12353 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12353:SF3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam GKAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dlgap2 PhenoGen
RatGTEx ENSRNOG00000012573 RatGTEx
UniProt A0A0G2JUI3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZQT2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A4U6 ENTREZGENE, UniProtKB/TrEMBL
  A6IWE1 ENTREZGENE, UniProtKB/TrEMBL
  A6IWE2_RAT UniProtKB/TrEMBL
  A6IWE3_RAT UniProtKB/TrEMBL
  DLGP2_RAT UniProtKB/Swiss-Prot
  F1LSL6 ENTREZGENE, UniProtKB/TrEMBL
  P97837 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-01 Dlgap2  DLG associated protein 2  Dlgap2  discs large homolog associated protein 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-01-27 Dlgap2  discs large homolog associated protein 2  Dlgap2  discs, large (Drosophila) homolog-associated protein 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Dlgap2  discs, large (Drosophila) homolog-associated protein 2      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Dlgap2  discs, large (Drosophila) homolog-associated protein 2      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to the synaptoneurosome fraction 629555
gene_expression protein is detected in the superior colliculus and visual cortex 629555
gene_process increased localization to dendrites is associated with eye opening 629555
gene_process may play a role in visual neuron development 629555
gene_process may play a role in maintaining postsynaptic densities by concentrating its components to that area 68237