Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Dlgap2 | Rat | (-)-cotinine | multiple interactions | ISO | DLGAP2 (Homo sapiens) | 6480464 | [Tobacco Smoke Pollution results in increased abundance of Cotinine] which affects the methylation of DLGAP2 more ... | CTD | PMID:34009014 | Dlgap2 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Dlgap2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DLGAP2 mRNA | CTD | PMID:17942748 | Dlgap2 | Rat | 2,3',4,4',5-Pentachlorobiphenyl | decreases expression | ISO | Dlgap2 (Mus musculus) | 6480464 | 2,3',4,4',5-pentachlorobiphenyl results in decreased expression of DLGAP2 mRNA | CTD | PMID:31388691 | Dlgap2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Dlgap2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DLGAP2 mRNA | CTD | PMID:17942748 | Dlgap2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DLGAP2 mRNA | CTD | PMID:32109520 | Dlgap2 | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | DLGAP2 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of DLGAP2 gene | CTD | PMID:31601247 | Dlgap2 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of DLGAP2 mRNA | CTD | PMID:24780913|PMID:37926403 | Dlgap2 | Rat | aflatoxin B1 | affects methylation | ISO | DLGAP2 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the methylation of DLGAP2 intron | CTD | PMID:30157460 | Dlgap2 | Rat | Aflatoxin B2 alpha | affects methylation | ISO | DLGAP2 (Homo sapiens) | 6480464 | aflatoxin B2 affects the methylation of DLGAP2 intron | CTD | PMID:30157460 | Dlgap2 | Rat | all-trans-retinoic acid | increases expression | ISO | Dlgap2 (Mus musculus) | 6480464 | Tretinoin results in increased expression of DLGAP2 mRNA | CTD | PMID:36189433 | Dlgap2 | Rat | all-trans-retinoic acid | multiple interactions | ISO | Dlgap2 (Mus musculus) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of DLGAP2 mRNA | CTD | PMID:36189433 | Dlgap2 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of DLGAP2 mRNA | CTD | PMID:16483693 | Dlgap2 | Rat | arsane | affects methylation | ISO | DLGAP2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of DLGAP2 gene | CTD | PMID:25304211 | Dlgap2 | Rat | arsenic atom | affects methylation | ISO | DLGAP2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of DLGAP2 gene | CTD | PMID:25304211 | Dlgap2 | Rat | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of DLGAP2 gene | CTD | PMID:28931070|PMID:35440735 | Dlgap2 | Rat | benzo[a]pyrene | increases methylation | ISO | Dlgap2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased methylation of DLGAP2 intron | CTD | PMID:27901495 | Dlgap2 | Rat | benzo[a]pyrene | decreases expression | ISO | DLGAP2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of DLGAP2 mRNA | CTD | PMID:32234424 | Dlgap2 | Rat | benzo[a]pyrene | affects methylation | ISO | DLGAP2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of DLGAP2 3' UTR; Benzo(a)pyrene affects the methylation of DLGAP2 5' more ... | CTD | PMID:27901495|PMID:30157460 | Dlgap2 | Rat | benzo[e]pyrene | affects methylation | ISO | DLGAP2 (Homo sapiens) | 6480464 | benzo(e)pyrene affects the methylation of DLGAP2 intron | CTD | PMID:30157460 | Dlgap2 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Dlgap2 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of DLGAP2 mRNA | CTD | PMID:34319233 | Dlgap2 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of DLGAP2 mRNA | CTD | PMID:25181051|PMID:30816183 | Dlgap2 | Rat | bisphenol A | affects methylation | ISO | DLGAP2 (Homo sapiens) | 6480464 | bisphenol A affects the methylation of DLGAP2 gene | CTD | PMID:31601247 | Dlgap2 | Rat | bisphenol A | multiple interactions | ISO | DLGAP2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of DLGAP2 gene | CTD | PMID:31601247 | Dlgap2 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of DLGAP2 gene | CTD | PMID:28505145 | Dlgap2 | Rat | Butylbenzyl phthalate | decreases methylation | ISO | Dlgap2 (Mus musculus) | 6480464 | butylbenzyl phthalate results in decreased methylation of DLGAP2 intron | CTD | PMID:28392331 | Dlgap2 | Rat | CGP 52608 | multiple interactions | ISO | DLGAP2 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to DLGAP2 gene] | CTD | PMID:28238834 | Dlgap2 | Rat | chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of DLGAP2 mRNA | CTD | PMID:18668222 | Dlgap2 | Rat | choline | multiple interactions | ISO | Dlgap2 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ... | CTD | PMID:20938992 | Dlgap2 | Rat | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of DLGAP2 mRNA | CTD | PMID:26577399|PMID:27523638 | Dlgap2 | Rat | dichloroacetic acid | increases expression | ISO | Dlgap2 (Mus musculus) | 6480464 | Dichloroacetic Acid results in increased expression of DLGAP2 mRNA | CTD | PMID:28962523 | Dlgap2 | Rat | dimethylarsinic acid | increases methylation | EXP | | 6480464 | Cacodylic Acid results in increased methylation of DLGAP2 gene | CTD | PMID:37958445 | Dlgap2 | Rat | disodium selenite | decreases expression | ISO | DLGAP2 (Homo sapiens) | 6480464 | Sodium Selenite results in decreased expression of DLGAP2 mRNA | CTD | PMID:18175754 | Dlgap2 | Rat | ethanol | affects splicing | ISO | Dlgap2 (Mus musculus) | 6480464 | Ethanol affects the splicing of DLGAP2 mRNA | CTD | PMID:30319688 | Dlgap2 | Rat | folic acid | multiple interactions | ISO | Dlgap2 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ... | CTD | PMID:20938992 | Dlgap2 | Rat | fulvestrant | multiple interactions | ISO | DLGAP2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of DLGAP2 gene | CTD | PMID:31601247 | Dlgap2 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of DLGAP2 mRNA | CTD | PMID:33387578 | Dlgap2 | Rat | ibuprofen | multiple interactions | EXP | | 6480464 | Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of DLGAP2 mRNA] | CTD | PMID:24333387 | Dlgap2 | Rat | L-methionine | multiple interactions | ISO | Dlgap2 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ... | CTD | PMID:20938992 | Dlgap2 | Rat | lead diacetate | multiple interactions | ISO | Dlgap2 (Mus musculus) | 6480464 | [lead acetate results in increased abundance of Lead] which results in increased methylation of DLGAP2 more ... | CTD | PMID:33445541 | Dlgap2 | Rat | lead(0) | multiple interactions | ISO | Dlgap2 (Mus musculus) | 6480464 | [lead acetate results in increased abundance of Lead] which results in increased methylation of DLGAP2 more ... | CTD | PMID:33445541 | Dlgap2 | Rat | levonorgestrel | multiple interactions | ISO | DLGAP2 (Homo sapiens) | 6480464 | [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of DLGAP2 mRNA | CTD | PMID:19074003 | Dlgap2 | Rat | memantine | multiple interactions | EXP | | 6480464 | Memantine inhibits the reaction [Streptozocin results in decreased expression of DLGAP2 mRNA] | CTD | PMID:24333387 | Dlgap2 | Rat | methapyrilene | affects methylation | ISO | DLGAP2 (Homo sapiens) | 6480464 | Methapyrilene affects the methylation of DLGAP2 intron | CTD | PMID:30157460 | Dlgap2 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of DLGAP2 gene | CTD | PMID:35440735 | Dlgap2 | Rat | mono(2-ethylhexyl) phthalate | multiple interactions | ISO | Dlgap2 (Mus musculus) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of DLGAP2 mRNA | CTD | PMID:36189433 | Dlgap2 | Rat | N-Nitrosopyrrolidine | decreases expression | ISO | DLGAP2 (Homo sapiens) | 6480464 | N-Nitrosopyrrolidine results in decreased expression of DLGAP2 mRNA | CTD | PMID:32234424 | Dlgap2 | Rat | Nor-9-carboxy-delta9-THC | multiple interactions | ISO | DLGAP2 (Homo sapiens) | 6480464 | [Cannabinoids results in increased abundance of 11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid] which affects the methylation of DLGAP2 gene | CTD | PMID:30521419 | Dlgap2 | Rat | paracetamol | decreases expression | ISO | DLGAP2 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of DLGAP2 mRNA | CTD | PMID:26690555 | Dlgap2 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of DLGAP2 mRNA | CTD | PMID:33387578 | Dlgap2 | Rat | sodium arsenite | affects methylation | ISO | DLGAP2 (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of DLGAP2 gene | CTD | PMID:28589171 | Dlgap2 | Rat | sodium arsenite | increases expression | ISO | DLGAP2 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of DLGAP2 mRNA | CTD | PMID:29301061|PMID:38568856 | Dlgap2 | Rat | streptozocin | multiple interactions | EXP | | 6480464 | Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of DLGAP2 mRNA]; Memantine inhibits the more ... | CTD | PMID:24333387 | Dlgap2 | Rat | streptozocin | decreases expression | EXP | | 6480464 | Streptozocin results in decreased expression of DLGAP2 mRNA | CTD | PMID:24333387 | Dlgap2 | Rat | testosterone undecanoate | multiple interactions | ISO | DLGAP2 (Homo sapiens) | 6480464 | [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of DLGAP2 mRNA | CTD | PMID:19074003 | Dlgap2 | Rat | titanium dioxide | decreases methylation | ISO | Dlgap2 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of DLGAP2 gene | CTD | PMID:35295148 | Dlgap2 | Rat | titanium dioxide | increases methylation | ISO | Dlgap2 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of DLGAP2 gene | CTD | PMID:35295148 | Dlgap2 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of DLGAP2 mRNA | CTD | PMID:33387578 | Dlgap2 | Rat | trichostatin A | decreases expression | ISO | DLGAP2 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of DLGAP2 mRNA | CTD | PMID:24935251 | Dlgap2 | Rat | troglitazone | decreases expression | EXP | | 6480464 | troglitazone results in decreased expression of DLGAP2 mRNA | CTD | PMID:21515302 | Dlgap2 | Rat | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of DLGAP2 mRNA | CTD | PMID:29427782 | Dlgap2 | Rat | valproic acid | affects splicing | EXP | | 6480464 | Valproic Acid affects the splicing of DLGAP2 mRNA | CTD | PMID:29427782 | | 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