Chn2 (chimerin 2) - Rat Genome Database

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Gene: Chn2 (chimerin 2) Rattus norvegicus
Analyze
Symbol: Chn2
Name: chimerin 2
RGD ID: 620140
Description: Enables GTPase activator activity. Involved in acrosome assembly. Predicted to be located in synapse. Orthologous to human CHN2 (chimerin 2); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: beta-chimaerin; beta-chimerin; chimerin (chimaerin) 2; rho GTPase-activating protein 3
RGD Orthologs
Human
Mouse
Dog
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8484,478,989 - 84,738,068 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl484,704,862 - 84,738,068 (+)EnsemblGRCr8
mRatBN7.2483,148,616 - 83,407,711 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl483,147,983 - 83,407,709 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx488,370,092 - 88,629,056 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0484,145,507 - 84,404,477 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0482,568,244 - 82,827,277 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0484,423,708 - 84,452,989 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl484,194,347 - 84,454,500 (+)Ensemblrn6Rnor6.0
Rnor_5.04149,084,648 - 149,113,929 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4482,649,232 - 82,678,513 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera478,252,779 - 78,282,084 (+)NCBICelera
RGSC_v3.1482,933,853 - 82,963,134 (+)NCBI
Cytogenetic Map4q24NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
Azoxymethane  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dextran sulfate  (ISO)
dibenz[a,h]anthracene  (ISO)
dibenzo[a,l]pyrene  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dimethyl sulfoxide  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
finasteride  (EXP)
flavonoids  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
GSK-J4  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
L-methionine  (ISO)
leflunomide  (EXP,ISO)
methapyrilene  (ISO)
methylmercury chloride  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-Nitrosopyrrolidine  (ISO)
nicotinic acid  (EXP)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorononanoic acid  (ISO)
permethrin  (EXP)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
quercetin  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tetrachloromethane  (EXP,ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)
synapse  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Germ cell beta-chimaerin, a new GTPase-activating protein for p21rac, is specifically expressed during the acrosomal assembly stage in rat testis. Leung T, etal., J Biol Chem 1993 Feb 25;268(6):3813-6.
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8175705  


Genomics

Comparative Map Data
Chn2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8484,478,989 - 84,738,068 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl484,704,862 - 84,738,068 (+)EnsemblGRCr8
mRatBN7.2483,148,616 - 83,407,711 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl483,147,983 - 83,407,709 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx488,370,092 - 88,629,056 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0484,145,507 - 84,404,477 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0482,568,244 - 82,827,277 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0484,423,708 - 84,452,989 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl484,194,347 - 84,454,500 (+)Ensemblrn6Rnor6.0
Rnor_5.04149,084,648 - 149,113,929 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4482,649,232 - 82,678,513 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera478,252,779 - 78,282,084 (+)NCBICelera
RGSC_v3.1482,933,853 - 82,963,134 (+)NCBI
Cytogenetic Map4q24NCBI
CHN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38729,146,591 - 29,514,328 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl729,146,547 - 29,514,334 (+)Ensemblhg38GRCh38
GRCh37729,186,207 - 29,553,944 (+)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map7p14.3NCBI
HuRef729,115,775 - 29,435,673 (+)NCBIHuRef
CHM1_1729,234,238 - 29,554,150 (+)NCBICHM1_1
T2T-CHM13v2.0729,284,405 - 29,652,211 (+)NCBIT2T-CHM13v2.0
Chn2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39654,016,917 - 54,278,797 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl654,016,539 - 54,278,795 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38654,039,932 - 54,301,812 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl654,039,554 - 54,301,810 (+)Ensemblmm10GRCm38
MGSCv37653,989,926 - 54,251,806 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36654,202,399 - 54,231,388 (+)NCBIMGSCv36mm8
Celera654,569,510 - 54,833,021 (+)NCBICelera
Cytogenetic Map6B3NCBI
cM Map626.54NCBI
CHN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11442,217,678 - 42,513,370 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1442,217,739 - 42,512,188 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1441,652,123 - 41,947,336 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01442,159,196 - 42,454,949 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1442,159,050 - 42,454,964 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11442,276,263 - 42,571,902 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01441,955,181 - 42,250,617 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01442,313,119 - 42,608,875 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Chn2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1686,785,958 - 87,046,537 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Chn2
1723 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:32
Count of miRNA genes:26
Interacting mature miRNAs:29
Transcripts:ENSRNOT00000012655
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)439431983123203361Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)459753119104753119Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44140057786400577Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44442502489425024Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)474233320119233320Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)480212111119233320Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)458817672103817672Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)426234499134199155Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)474233320119233320Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)471647492116647492Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482944895154403548Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)427862204126119996Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44140060386400603Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)475939858140508796Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)465060960127749483Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)445429897149763204Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)451085655113588029Rat
61364Iddm2Insulin dependent diabetes mellitus QTL 2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)480216705104243248Rat
2317588Eae27Experimental allergic encephalomyelitis QTL 27nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)469036742114036742Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)440490442117737312Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)457613339151163960Rat
4889969Bss96Bone structure and strength QTL 964.9tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)457613242102613242Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
4889972Bss97Bone structure and strength QTL 975.6tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)457613242102613242Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat
5685009Bmd86Bone mineral density QTL 863.7tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)457613242102613242Rat
2306794Ean2Experimental allergic neuritis QTL 26.4nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)48279077797183061Rat
2306547Iddm38Insulin dependent diabetes mellitus QTL 38blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)468353567113353567Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
2306545Iddm39Insulin dependent diabetes mellitus QTL 39blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)478687630123687630Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41170660492690519Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)474169813134199155Rat
2312569Pur19Proteinuria QTL 193.40.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)459836842104836842Rat
61406Scwia1Streptococcal cell wall induced arthritis QTL 12.3joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)475939858140508796Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)445429897149763204Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)46104105794638356Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)484349032129349032Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)445429709157555683Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)463245026129846354Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)464209744109209744Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1558651Swd3Spike wave discharge measurement QTL 34.620.000024brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)44140057786400577Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)457664252127749483Rat
2306899Bp338Blood pressure QTL 3380.071arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)482336765127336765Rat
631546Bp86Blood pressure QTL 863.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45807987592690793Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)465495851159259805Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat
61434Cia3Collagen induced arthritis QTL 34.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)463224393108224393Rat
7394826Bw126Body weight QTL 1260.002body mass (VT:0001259)body weight gain (CMO:0000420)46390045888813920Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)433538597116185060Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000012655   ⟹   ENSRNOP00000012655
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl484,707,260 - 84,736,551 (+)Ensembl
mRatBN7.2 Ensembl483,376,899 - 83,406,175 (+)Ensembl
Rnor_6.0 Ensembl484,423,653 - 84,452,972 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000084256   ⟹   ENSRNOP00000070229
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl483,283,214 - 83,407,709 (+)Ensembl
Rnor_6.0 Ensembl484,194,347 - 84,454,500 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097181   ⟹   ENSRNOP00000083538
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl484,707,289 - 84,736,550 (+)Ensembl
mRatBN7.2 Ensembl483,377,533 - 83,407,709 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097615   ⟹   ENSRNOP00000077359
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl483,147,983 - 83,407,709 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000100224   ⟹   ENSRNOP00000077273
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl484,707,289 - 84,736,338 (+)Ensembl
mRatBN7.2 Ensembl483,377,533 - 83,405,981 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101363   ⟹   ENSRNOP00000085806
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl483,147,983 - 83,407,709 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000103158   ⟹   ENSRNOP00000093988
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl484,707,289 - 84,736,550 (+)Ensembl
mRatBN7.2 Ensembl483,377,533 - 83,407,709 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000106897   ⟹   ENSRNOP00000096033
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl483,302,401 - 83,406,952 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112440   ⟹   ENSRNOP00000082836
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl484,704,862 - 84,738,068 (+)Ensembl
mRatBN7.2 Ensembl483,374,505 - 83,407,709 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119878   ⟹   ENSRNOP00000089974
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl484,707,289 - 84,736,550 (+)Ensembl
mRatBN7.2 Ensembl483,377,533 - 83,407,709 (+)Ensembl
RefSeq Acc Id: NM_032084   ⟹   NP_114473
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8484,478,989 - 84,738,068 (+)NCBI
mRatBN7.2483,148,616 - 83,407,711 (+)NCBI
Rnor_6.0484,423,708 - 84,452,989 (+)NCBI
Rnor_5.04149,084,648 - 149,113,929 (+)NCBI
RGSC_v3.4482,649,232 - 82,678,513 (+)RGD
Celera478,252,779 - 78,282,084 (+)RGD
Sequence:
RefSeq Acc Id: XM_039108464   ⟹   XP_038964392
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8484,624,920 - 84,736,551 (+)NCBI
mRatBN7.2483,294,596 - 83,407,706 (+)NCBI
RefSeq Acc Id: XM_039108465   ⟹   XP_038964393
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8484,700,750 - 84,736,551 (+)NCBI
mRatBN7.2483,370,556 - 83,407,706 (+)NCBI
RefSeq Acc Id: XM_039108466   ⟹   XP_038964394
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8484,707,175 - 84,736,551 (+)NCBI
mRatBN7.2483,376,918 - 83,407,706 (+)NCBI
RefSeq Acc Id: XM_039108467   ⟹   XP_038964395
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8484,700,753 - 84,736,551 (+)NCBI
mRatBN7.2483,370,556 - 83,407,706 (+)NCBI
RefSeq Acc Id: XM_063286763   ⟹   XP_063142833
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8484,630,192 - 84,736,551 (+)NCBI
RefSeq Acc Id: XM_063286764   ⟹   XP_063142834
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8484,707,234 - 84,736,551 (+)NCBI
RefSeq Acc Id: NP_114473   ⟸   NM_032084
- UniProtKB: A0A8I5Y7G2 (UniProtKB/TrEMBL),   A6K0U4 (UniProtKB/TrEMBL),   A0A8I6A2H3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000012655   ⟸   ENSRNOT00000012655
Ensembl Acc Id: ENSRNOP00000070229   ⟸   ENSRNOT00000084256
RefSeq Acc Id: XP_038964392   ⟸   XM_039108464
- Peptide Label: isoform X1
- UniProtKB: Q03070 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038964393   ⟸   XM_039108465
- Peptide Label: isoform X2
- UniProtKB: Q03070 (UniProtKB/Swiss-Prot),   G3V773 (UniProtKB/TrEMBL),   A6K0U6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038964395   ⟸   XM_039108467
- Peptide Label: isoform X3
- UniProtKB: Q03070 (UniProtKB/Swiss-Prot),   A0A8I5ZYQ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038964394   ⟸   XM_039108466
- Peptide Label: isoform X2
- UniProtKB: Q03070 (UniProtKB/Swiss-Prot),   G3V773 (UniProtKB/TrEMBL),   A6K0U6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000082836   ⟸   ENSRNOT00000112440
Ensembl Acc Id: ENSRNOP00000085806   ⟸   ENSRNOT00000101363
Ensembl Acc Id: ENSRNOP00000077273   ⟸   ENSRNOT00000100224
Ensembl Acc Id: ENSRNOP00000089974   ⟸   ENSRNOT00000119878
Ensembl Acc Id: ENSRNOP00000077359   ⟸   ENSRNOT00000097615
Ensembl Acc Id: ENSRNOP00000096033   ⟸   ENSRNOT00000106897
Ensembl Acc Id: ENSRNOP00000093988   ⟸   ENSRNOT00000103158
Ensembl Acc Id: ENSRNOP00000083538   ⟸   ENSRNOT00000097181
RefSeq Acc Id: XP_063142833   ⟸   XM_063286763
- Peptide Label: isoform X1
- UniProtKB: Q03070 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063142834   ⟸   XM_063286764
- Peptide Label: isoform X2
- UniProtKB: Q03070 (UniProtKB/Swiss-Prot),   A6K0U6 (UniProtKB/TrEMBL),   G3V773 (UniProtKB/TrEMBL)
Protein Domains
Phorbol-ester/DAG-type   Rho-GAP   SH2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q03070-F1-model_v2 AlphaFold Q03070 1-295 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620140 AgrOrtholog
BioCyc Gene G2FUF-44777 BioCyc
Ensembl Genes ENSRNOG00000009411 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000012655 ENTREZGENE
  ENSRNOT00000112440 ENTREZGENE
Gene3D-CATH 1.10.555.10 UniProtKB/Swiss-Prot
  3.30.60.20 UniProtKB/Swiss-Prot
InterPro C1-like_sf UniProtKB/Swiss-Prot
  DAG/PE-bd UniProtKB/Swiss-Prot
  PE/DAG-bd UniProtKB/Swiss-Prot
  Rho-type_GAP UniProtKB/Swiss-Prot
  Rho_GTPase_activation_prot UniProtKB/Swiss-Prot
  RhoGAP_chimaerin UniProtKB/Swiss-Prot
  RhoGAP_dom UniProtKB/Swiss-Prot
KEGG Report rno:84031 UniProtKB/Swiss-Prot
NCBI Gene 84031 ENTREZGENE
PANTHER BETA-CHIMAERIN UniProtKB/Swiss-Prot
  CHIMERIN FAMILY MEMBER UniProtKB/Swiss-Prot
Pfam C1_1 UniProtKB/Swiss-Prot
  RhoGAP UniProtKB/Swiss-Prot
PhenoGen Chn2 PhenoGen
PRINTS DAGPEDOMAIN UniProtKB/Swiss-Prot
PROSITE RHOGAP UniProtKB/Swiss-Prot
  ZF_DAG_PE_1 UniProtKB/Swiss-Prot
  ZF_DAG_PE_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000009411 RatGTEx
SMART RhoGAP UniProtKB/Swiss-Prot
  SM00109 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48350 UniProtKB/Swiss-Prot
  SSF57889 UniProtKB/Swiss-Prot
UniProt A0A8I5Y1D7_RAT UniProtKB/TrEMBL
  A0A8I5Y7G2 ENTREZGENE
  A0A8I5ZXE2_RAT UniProtKB/TrEMBL
  A0A8I5ZYQ0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A2H3 ENTREZGENE
  A0A8I6AAW8_RAT UniProtKB/TrEMBL
  A0A8I6GKJ0_RAT UniProtKB/TrEMBL
  A6K0U4 ENTREZGENE, UniProtKB/TrEMBL
  A6K0U6 ENTREZGENE, UniProtKB/TrEMBL
  CHIO_RAT UniProtKB/Swiss-Prot
  G3V773 ENTREZGENE, UniProtKB/TrEMBL
  Q03070 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-01 Chn2  chimerin 2  Chn2  chimerin (chimaerin) 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Chn2  chimerin (chimaerin) 2      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Chn2  chimerin (chimaerin) 2      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression present at testicular germ cells during acrosomal assembly 724725
gene_protein 34 kDa 724725