CHN2 (chimerin 2) - Rat Genome Database

Name: CHN2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: CHN2 (chimerin 2) Canis lupus familiaris

Analyze

Symbol:

CHN2

Name:

chimerin 2

RGD ID:

12188282

Description:

ENCODES a protein that exhibits GTPase activator activity (ortholog); INVOLVED IN acrosome assembly (ortholog); ASSOCIATED WITH Congenital Hypomyelinating Neuropathy 2 (ortholog); Liver Neoplasms (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN synapse (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

beta-chimaerin; chimerin (chimaerin) 2

RGD Orthologs

Human

Mouse

Rat

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	14	42,217,678 - 42,513,370 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	14	42,217,739 - 42,512,188 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	14	41,652,123 - 41,947,336 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	14	42,159,196 - 42,454,949 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	14	42,159,050 - 42,454,964 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	14	42,276,263 - 42,571,902 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	14	41,955,181 - 42,250,617 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	14	42,313,119 - 42,608,875 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Congenital Hypomyelinating Neuropathy 2 (ISO)

Liver Neoplasms (ISO)

pleomorphic xanthoastrocytoma (ISO)

pre-malignant neoplasm (ISO)

schizophrenia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

acrosome assembly (ISO)

regulation of small GTPase mediated signal transduction (IEA)

signal transduction (IEA)

Cellular Component

synapse (IEA)

Molecular Function

GTPase activator activity (IEA,ISO)

metal ion binding (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

CHN2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	14	42,217,678 - 42,513,370 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	14	42,217,739 - 42,512,188 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	14	41,652,123 - 41,947,336 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	14	42,159,196 - 42,454,949 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	14	42,159,050 - 42,454,964 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	14	42,276,263 - 42,571,902 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	14	41,955,181 - 42,250,617 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	14	42,313,119 - 42,608,875 (+)	NCBI		UU_Cfam_GSD_1.0

CHN2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	29,146,591 - 29,514,328 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	29,146,547 - 29,514,328 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	29,186,207 - 29,553,944 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Cytogenetic Map	7	p14.3	NCBI
HuRef	7	29,115,775 - 29,435,673 (+)	NCBI		HuRef
CHM1_1	7	29,234,238 - 29,554,150 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	7	29,284,405 - 29,652,211 (+)	NCBI		T2T-CHM13v2.0

Chn2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	54,016,917 - 54,278,797 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	54,016,539 - 54,278,795 (+)	Ensembl		GRCm39 Ensembl
GRCm38	6	54,039,932 - 54,301,812 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	54,039,554 - 54,301,810 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	53,989,926 - 54,251,806 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	54,202,399 - 54,231,388 (+)	NCBI		MGSCv36	mm8
Celera	6	54,569,510 - 54,833,021 (+)	NCBI		Celera
Cytogenetic Map	6	B3	NCBI
cM Map	6	26.54	NCBI

Chn2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	84,478,989 - 84,738,068 (+)	NCBI		GRCr8
mRatBN7.2	4	83,148,616 - 83,407,711 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	83,147,983 - 83,407,709 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	88,370,092 - 88,629,056 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	84,145,507 - 84,404,477 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	82,568,244 - 82,827,277 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	84,423,708 - 84,452,989 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	84,194,347 - 84,454,500 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	149,084,648 - 149,113,929 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	82,649,232 - 82,678,513 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	82,933,853 - 82,963,134 (+)	NCBI
Celera	4	78,252,779 - 78,282,084 (+)	NCBI		Celera
Cytogenetic Map	4	q24	NCBI

Variants

Variants in CHN2
3801 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium			8	3	5	3			6		9
Low	5	5	14	3	1	3	6	1	6		1	6
Below cutoff								5		8

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_014119074	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_014119075	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038494943	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038494944	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038557212	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038557213	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038621152	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038621153	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038686834	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038686835	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_532501	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000159	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000208	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000037549 ⟹ ENSCAFP00000033083

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	14	42,217,739 - 42,512,003 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000065758 ⟹ ENSCAFP00000057554

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	14	42,478,680 - 42,512,188 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000067084 ⟹ ENSCAFP00000055772

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	14	42,478,680 - 42,512,188 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000076329 ⟹ ENSCAFP00000053988

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	14	42,478,680 - 42,512,003 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000088627 ⟹ ENSCAFP00000058718

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	14	42,478,680 - 42,511,546 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845031726 ⟹ ENSCAFP00845024830

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	14	42,159,050 - 42,453,586 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845031820 ⟹ ENSCAFP00845024895

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	14	42,159,060 - 42,454,964 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845031956 ⟹ ENSCAFP00845024989

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	14	42,159,060 - 42,454,964 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845032054 ⟹ ENSCAFP00845025062

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	14	42,247,468 - 42,454,964 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845032180 ⟹ ENSCAFP00845025158

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	14	42,255,834 - 42,454,964 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845032291 ⟹ ENSCAFP00845025243

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	14	42,420,334 - 42,453,126 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845032365 ⟹ ENSCAFP00845025298

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	14	42,420,400 - 42,454,944 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845032418 ⟹ ENSCAFP00845025345

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	14	42,420,400 - 42,454,944 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845032450 ⟹ ENSCAFP00845025368

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	14	42,420,400 - 42,454,944 (+)	Ensembl

RefSeq Acc Id:

XM_014119074 ⟹ XP_013974549

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	14	42,478,614 - 42,513,370 (+)	NCBI
Dog10K_Boxer_Tasha	14	41,912,690 - 41,947,336 (+)	NCBI

Sequence:

show sequence

TGCAGACAGGACGCAGCTGCCTCGAATCTGCTGCCTGACATTAGCCGCGGTTCGGAAGACCTGC
CAGCGCTGAGCCTTCACGGGGGAATCTAGAAGGATGTGGGGTGCAGGCACTATGTTCTCCGAGG
AACTGTGGCCGGAAAATGAGAAAAAATGTGCGGTGCTTCGGAAGCCTAAGCAAGATCTCGTCCC
TGGTCCGAAGGGCCGCCCTCACGCACAACGACAACCACTTCAACTACGAGAAGACCCACAACTT
CAAGGTCCATACATTCCGAGGCCCGCACTGGTGTGAATACTGTGCCAACTTCATGTGGGGGCTC
ATTGCCCAAGGGGTTCGGTGCTCAGACTGTGGATTGAATGTACACAAACAGTGTTCCAAGCACG
TTCCCAACGACTGTCAACCTGATCTCAAGAGGATTAAGAAGGTGTACTGTTGTGACCTCACAAC
ACTTGTGAAGGCTCACAATACTCAGAGACCCATGGTGGTAGACATATGCATACGGGAAATTGAA
GCAAGAGGATTGAAGTCAGAAGGCCTTTACAGAGTCTCTGGGTTCACTGAACACATCGAAGATG
TCAAGATGGCATTTGACAGAGATGGTGAAAAGGCAGATATATCTGCCAACATCTACCCAGACAT
AAACATCATCACTGGAGCCCTTAAACTATACTTCAGAGACTTACCCATTCCTGTTATCACCTAT
GACACCTATCCCAAATTTATTGAGGCAGCAAAAATCTCCAACGCAGATGAGAGGCTGGAAGCCG
TCCATGACGTGCTGATGCTGCTGCCCCCTGCCCACTATGAGACCCTCCGATACCTGATGATCCA
CCTCAAGAAGGTGACTATGAATGAGAAGGACAATTTCATGAATGCTGAAAATCTGGGGATCGTG
TTTGGGCCCACACTGATGAGGTCCCCTGAGGACAGCACCCTCACCACCCTCCATGATATGCGGT
ACCAAAAGCTGATCGTGCAGATTTTAATAGAAAATGAAGATGTTTTGTTTTAATCCTCCAGGGA
AATGAGCCTCATGGCCCCAGCCCCATCTAAGTTGATAAGGCTAGAGGAGTAAAAACATTTCTTA
CACTTGATTCGTTTTCCAAACAAATGAGAGAATTTCCAGGACCACAGTGGATTTGTCAAGTCGG
CTACTGTGTCTCATAGACACTCGCCTCCTCCACGTAAGAACAGCAGGGGTGAGAGTGACCAAAG
GCCTCCTCTTGGGTCTCTGCTGTGCCTCCTACATATGCCTGTTTTGCTGGAAGAGTGATTAATA
AATCTTTCTTTAACTTATTAAAAAAAAAAAAAAACAACCTAGATCTTTAAGCTTCCGTCTTATC
AGTAATTAAAGGGAATTTAATTCATAGAGGTACTTGATACAGTTATACATTTTCCACTTACAGA
AAGAAGACAATTCTATGTTAAATGTTAAATGAAACTTATATTGTAAAATGTATTTTTATTTTAG
CTGCAAGAATGTTACTTTATTTCAGCAAATAGAACTCAATGCAGTGCATTGATTATGACCCTGT
GTACCTTGTCCTGCTTCTTGCTGTGATCCCTGAAAAAGTTTACCATGAATGCAGTATTATCTTG
ACATACCTCTGTCCTTATCAGTGCTTTGCAATGAAAGTTCACCGGCCACCTGTGTCCCTGCTTT
TGATAGGTTTTGCTGTTGAGCACTGGCATTTTGCAGTCGTACGGTATATGTTTATAGCAATTGT
AGGATGGTCTGAAACATCCACAGATTTTCTTTCCTTAGACATTTTGTGAAATCCCAAAGTATGT
TTTGCCATTGGTCAGAGTCTCTCCGTATCATGTGTGTATATCCCAGAACATGCAGAATGTGGTC
ATTTTACATAAAATGATGCGGGATGGTTAAATCTGGGCCATGTAAAAAGTTAACACTTTCCCTA
GGTTCTTTTCGGTCCAGCACTCTGAATTCACCTATTAATGACAAGTTGTATTTTTGTCACATTT
CTGTATTTAGGAAAAGTGAATCTGCAGAAAAATTACTGATTTTTTTCCATTTTTGCTTTATAAA
CAAGCCTATTTTTAAAAGTAAGAATGAGTAAGTTTGGTTTTTACAAATATTTGTTCCTCCTTGA
CAAAAGTAGCTCTGTATGGATCATAATTTAATATGATTTTATCATGATAGTTCCATCTTCTTGG
TTATATTTATCTTAGCATGAGCTTTTCACAGCAAGATTTCTATATTTTGTAACATAGGTAAAAT
TTTAAAGCATCAAAAACTGTAAATCTAAATTTTTTTTTCTGAAATCCAACCACAATGTCTTTTC
CTCTGATTGTCTAAGATGATCCATGTACTTACTCACTAGTCTTGTTTTTGAGTGAACAGAAGAG
AATTACTGTGTGATAAATGATCTGGAATGAGGAGGGCAGTGCAATTGTTGTCCTGGACAGTCCC
AAGGGCTACGCGGATGGACTTCGTTGGCACACCGGGGGGGGTTAAAATGGTTCTGCTGGGTCCC
TGCTATTATTGTTCCTCCCAACTGTACAGATTTGTTTGTTGTAGCTTATGTACTTCTTGATACT
GTCAAAAAATTATCTGAAAATGGTTTTATTTTGTGAAGTGAATAATACTTTGTAATTTATGATA
GTGTAAATGGAAGGAAAAGCATTAAATGTATTAAATTCTTCTGTCTATCATC

hide sequence

RefSeq Acc Id:

XM_038494943 ⟹ XP_038350871

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	14	42,276,263 - 42,571,902 (+)	NCBI

RefSeq Acc Id:

XM_038494944 ⟹ XP_038350872

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	14	42,537,305 - 42,571,902 (+)	NCBI

RefSeq Acc Id:

XM_038557212 ⟹ XP_038413140

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	14	42,313,119 - 42,608,875 (+)	NCBI

RefSeq Acc Id:

XM_038557213 ⟹ XP_038413141

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	14	42,574,217 - 42,608,875 (+)	NCBI

RefSeq Acc Id:

XM_038621152 ⟹ XP_038477080

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	14	41,955,181 - 42,250,617 (+)	NCBI

RefSeq Acc Id:

XM_038621153 ⟹ XP_038477081

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	14	42,215,963 - 42,250,617 (+)	NCBI

RefSeq Acc Id:

XM_038686834 ⟹ XP_038542762

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	14	42,159,196 - 42,454,949 (+)	NCBI

RefSeq Acc Id:

XM_038686835 ⟹ XP_038542763

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	14	42,420,278 - 42,454,949 (+)	NCBI

RefSeq Acc Id:

XM_532501 ⟹ XP_532501

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	14	42,217,678 - 42,513,370 (+)	NCBI
Dog10K_Boxer_Tasha	14	41,652,123 - 41,947,336 (+)	NCBI

Sequence:

show sequence

TAAGTGCAAGCGGAGTCCGGAGGCTGGGGCTCCGCGCGCTTCCCCAGGACTTTGCCATGGGCTG
GGGGCCGCGGGGGCAGCGGCGGCGGCGTCCGCACCCGCACCGGGGCTGAGCAGCAGCGACGCGC
GGGGCGCGAGATGGCAGCGTCCAGCAACTCCAGCCTGTCCGGCTCCTCCGTGTCCTCCGATGCT
GAAGAATACCAGCCTCCAATATGGAAATCATACTTGTATCAATTACAGCAAGAGGCCCCTCGTC
CCAAGAGGATCATTTGTCCTGGGGAGGTGGAGAACAGACCAAAATATTATGGAAGAGAGTTTCA
CGGGATCATCTCCCGGGAACAGGCAGACGAGCTTCTCGGAGGCGTGGAGGGCGCCTACATTCTT
AGAGAAAGTCAGCGCCAGCCAGGATGCTACACATTAGCTCTCAGATTTGGAAACCAGACTTTAA
ACTACAGGCTCTTCTATGATGGAAAACACTTTGTGGGCGAGAAGAGGTTTGAATCGATTCACGA
TCTGGTCACAGATGGCTTGATAACATTGTACATAGAAACAAAGGCTTCTGAATACATTTCCAAA
ATGACAACAAACCCCATTTATGAACACATTGGATATGCCACTCTACTCCGAGAAAAAGTATCCA
GGAGGCTGAGCAGGTCTAAAAATGAATCAAGAAAAACAAGCGTTACAAATGAAGAACACACAAC
AGTTGAAAAGATCTCGTCCCTGGTCCGAAGGGCCGCCCTCACGCACAACGACAACCACTTCAAC
TACGAGAAGACCCACAACTTCAAGGTCCATACATTCCGAGGCCCGCACTGGTGTGAATACTGTG
CCAACTTCATGTGGGGGCTCATTGCCCAAGGGGTTCGGTGCTCAGACTGTGGATTGAATGTACA
CAAACAGTGTTCCAAGCACGTTCCCAACGACTGTCAACCTGATCTCAAGAGGATTAAGAAGGTG
TACTGTTGTGACCTCACAACACTTGTGAAGGCTCACAATACTCAGAGACCCATGGTGGTAGACA
TATGCATACGGGAAATTGAAGCAAGAGGATTGAAGTCAGAAGGCCTTTACAGAGTCTCTGGGTT
CACTGAACACATCGAAGATGTCAAGATGGCATTTGACAGAGATGGTGAAAAGGCAGATATATCT
GCCAACATCTACCCAGACATAAACATCATCACTGGAGCCCTTAAACTATACTTCAGAGACTTAC
CCATTCCTGTTATCACCTATGACACCTATCCCAAATTTATTGAGGCAGCAAAAATCTCCAACGC
AGATGAGAGGCTGGAAGCCGTCCATGACGTGCTGATGCTGCTGCCCCCTGCCCACTATGAGACC
CTCCGATACCTGATGATCCACCTCAAGAAGGTGACTATGAATGAGAAGGACAATTTCATGAATG
CTGAAAATCTGGGGATCGTGTTTGGGCCCACACTGATGAGGTCCCCTGAGGACAGCACCCTCAC
CACCCTCCATGATATGCGGTACCAAAAGCTGATCGTGCAGATTTTAATAGAAAATGAAGATGTT
TTGTTTTAATCCTCCAGGGAAATGAGCCTCATGGCCCCAGCCCCATCTAAGTTGATAAGGCTAG
AGGAGTAAAAACATTTCTTACACTTGATTCGTTTTCCAAACAAATGAGAGAATTTCCAGGACCA
CAGTGGATTTGTCAAGTCGGCTACTGTGTCTCATAGACACTCGCCTCCTCCACGTAAGAACAGC
AGGGGTGAGAGTGACCAAAGGCCTCCTCTTGGGTCTCTGCTGTGCCTCCTACATATGCCTGTTT
TGCTGGAAGAGTGATTAATAAATCTTTCTTTAACTTATTAAAAAAAAAAAAAAACAACCTAGAT
CTTTAAGCTTCCGTCTTATCAGTAATTAAAGGGAATTTAATTCATAGAGGTACTTGATACAGTT
ATACATTTTCCACTTACAGAAAGAAGACAATTCTATGTTAAATGTTAAATGAAACTTATATTGT
AAAATGTATTTTTATTTTAGCTGCAAGAATGTTACTTTATTTCAGCAAATAGAACTCAATGCAG
TGCATTGATTATGACCCTGTGTACCTTGTCCTGCTTCTTGCTGTGATCCCTGAAAAAGTTTACC
ATGAATGCAGTATTATCTTGACATACCTCTGTCCTTATCAGTGCTTTGCAATGAAAGTTCACCG
GCCACCTGTGTCCCTGCTTTTGATAGGTTTTGCTGTTGAGCACTGGCATTTTGCAGTCGTACGG
TATATGTTTATAGCAATTGTAGGATGGTCTGAAACATCCACAGATTTTCTTTCCTTAGACATTT
TGTGAAATCCCAAAGTATGTTTTGCCATTGGTCAGAGTCTCTCCGTATCATGTGTGTATATCCC
AGAACATGCAGAATGTGGTCATTTTACATAAAATGATGCGGGATGGTTAAATCTGGGCCATGTA
AAAAGTTAACACTTTCCCTAGGTTCTTTTCGGTCCAGCACTCTGAATTCACCTATTAATGACAA
GTTGTATTTTTGTCACATTTCTGTATTTAGGAAAAGTGAATCTGCAGAAAAATTACTGATTTTT
TTCCATTTTTGCTTTATAAACAAGCCTATTTTTAAAAGTAAGAATGAGTAAGTTTGGTTTTTAC
AAATATTTGTTCCTCCTTGACAAAAGTAGCTCTGTATGGATCATAATTTAATATGATTTTATCA
TGATAGTTCCATCTTCTTGGTTATATTTATCTTAGCATGAGCTTTTCACAGCAAGATTTCTATA
TTTTGTAACATAGGTAAAATTTTAAAGCATCAAAAACTGTAAATCTAAATTTTTTTTTCTGAAA
TCCAACCACAATGTCTTTTCCTCTGATTGTCTAAGATGATCCATGTACTTACTCACTAGTCTTG
TTTTTGAGTGAACAGAAGAGAATTACTGTGTGATAAATGATCTGGAATGAGGAGGGCAGTGCAA
TTGTTGTCCTGGACAGTCCCAAGGGCTACGCGGATGGACTTCGTTGGCACACCGGGGGGGGTTA
AAATGGTTCTGCTGGGTCCCTGCTATTATTGTTCCTCCCAACTGTACAGATTTGTTTGTTGTAG
CTTATGTACTTCTTGATACTGTCAAAAAATTATCTGAAAATGGTTTTATTTTGTGAAGTGAATA
ATACTTTGTAATTTATGATAGTGTAAATGGAAGGAAAAGCATTAAATGTATTAAATTCTTCTGT
CTATCATC

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Protein Sequences


Protein RefSeqs	XP_013974549	(Get FASTA)	NCBI Sequence Viewer
	XP_038350871	(Get FASTA)	NCBI Sequence Viewer
	XP_038350872	(Get FASTA)	NCBI Sequence Viewer
	XP_038413140	(Get FASTA)	NCBI Sequence Viewer
	XP_038413141	(Get FASTA)	NCBI Sequence Viewer
	XP_038477080	(Get FASTA)	NCBI Sequence Viewer
	XP_038477081	(Get FASTA)	NCBI Sequence Viewer
	XP_038542762	(Get FASTA)	NCBI Sequence Viewer
	XP_038542763	(Get FASTA)	NCBI Sequence Viewer
	XP_532501	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000033083.3
	ENSCAFP00000053988.1
	ENSCAFP00000055772.1
	ENSCAFP00000057554.1
	ENSCAFP00000058718.1
	ENSCAFP00000067017.1
	ENSCAFP00000067993.1
	ENSCAFP00000070215.1
	ENSCAFP00000071471.1
	ENSCAFP00030010470.1
	ENSCAFP00030010534.1
	ENSCAFP00030010574.1
	ENSCAFP00030010632.1
	ENSCAFP00030010705.1
	ENSCAFP00030010773.1
	ENSCAFP00030010858.1
	ENSCAFP00030010870.1
	ENSCAFP00030010886.1
	ENSCAFP00030010897.1
	ENSCAFP00040017878.1
	ENSCAFP00040017950.1
	ENSCAFP00040018039.1
	ENSCAFP00040018177.1
	ENSCAFP00040018217.1
	ENSCAFP00040018250.1
	ENSCAFP00040018282.1
	ENSCAFP00845024830.1
	ENSCAFP00845024895
	ENSCAFP00845024895.1
	ENSCAFP00845024989.1
	ENSCAFP00845025062.1
	ENSCAFP00845025158.1
	ENSCAFP00845025243.1
	ENSCAFP00845025298.1
	ENSCAFP00845025345.1
	ENSCAFP00845025368.1

RefSeq Acc Id:	XP_532501 ⟸ XM_532501
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0S9H2 (UniProtKB/TrEMBL), A0A8I3NV41 (UniProtKB/TrEMBL), A0A8I3NU16 (UniProtKB/TrEMBL), A0A8P0SQC4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAASSNSSLSGSSVSSDAEEYQPPIWKSYLYQLQQEAPRPKRIICPGEVENRPKYYGREFHGII SREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRLFYDGKHFVGEKRFESIHDLVT DGLITLYIETKASEYISKMTTNPIYEHIGYATLLREKVSRRLSRSKNESRKTSVTNEEHTTVEK ISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQC SKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEH IEDVKMAFDRDGEKADISANIYPDINIITGALKLYFRDLPIPVITYDTYPKFIEAAKISNADER LEAVHDVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRSPEDSTLTTLH DMRYQKLIVQILIENEDVLF hide sequence

RefSeq Acc Id:	XP_013974549 ⟸ XM_014119074
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0JU01 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRKNVRCFGSLSKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGV RCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLK SEGLYRVSGFTEHIEDVKMAFDRDGEKADISANIYPDINIITGALKLYFRDLPIPVITYDTYPK FIEAAKISNADERLEAVHDVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTL MRSPEDSTLTTLHDMRYQKLIVQILIENEDVLF hide sequence

RefSeq Acc Id:

ENSCAFP00000058718 ⟸ ENSCAFT00000088627

RefSeq Acc Id:

ENSCAFP00000053988 ⟸ ENSCAFT00000076329

RefSeq Acc Id:

ENSCAFP00000033083 ⟸ ENSCAFT00000037549

RefSeq Acc Id:

ENSCAFP00000055772 ⟸ ENSCAFT00000067084

RefSeq Acc Id:

ENSCAFP00000057554 ⟸ ENSCAFT00000065758

RefSeq Acc Id:	XP_038350871 ⟸ XM_038494943
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038350872 ⟸ XM_038494944
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038477080 ⟸ XM_038621152
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038477081 ⟸ XM_038621153
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038542762 ⟸ XM_038686834
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0S9H2 (UniProtKB/TrEMBL), A0A8I3NV41 (UniProtKB/TrEMBL), A0A8I3NU16 (UniProtKB/TrEMBL), A0A8P0SQC4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038542763 ⟸ XM_038686835
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0JU01 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038413140 ⟸ XM_038557212
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0S9H2 (UniProtKB/TrEMBL), A0A8I3NU16 (UniProtKB/TrEMBL), A0A8I3NV41 (UniProtKB/TrEMBL), A0A8P0SQC4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038413141 ⟸ XM_038557213
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0JU01 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845024989 ⟸ ENSCAFT00845031956

RefSeq Acc Id:

ENSCAFP00845025345 ⟸ ENSCAFT00845032418

RefSeq Acc Id:

ENSCAFP00845025243 ⟸ ENSCAFT00845032291

RefSeq Acc Id:

ENSCAFP00845025158 ⟸ ENSCAFT00845032180

RefSeq Acc Id:

ENSCAFP00845025368 ⟸ ENSCAFT00845032450

RefSeq Acc Id:

ENSCAFP00845025062 ⟸ ENSCAFT00845032054

RefSeq Acc Id:

ENSCAFP00845024895 ⟸ ENSCAFT00845031820

RefSeq Acc Id:

ENSCAFP00845024830 ⟸ ENSCAFT00845031726

RefSeq Acc Id:

ENSCAFP00845025298 ⟸ ENSCAFT00845032365

Protein Domains

Phorbol-ester/DAG-type Rho-GAP SH2

Promoters

RGD ID:

13685796

Promoter ID:

EPDNEW_C3864

Type:

initiation region

Name:

CHN2_1

Description:

chimerin 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	14	42,217,668 - 42,217,728	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000003023	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030006432	UniProtKB/TrEMBL
	ENSCAFG00040011159	UniProtKB/TrEMBL
	ENSCAFG00845017921	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000037549.4	UniProtKB/TrEMBL
	ENSCAFT00000065758.2	UniProtKB/TrEMBL
	ENSCAFT00000067084.2	UniProtKB/TrEMBL
	ENSCAFT00000076329.2	UniProtKB/TrEMBL
	ENSCAFT00000088627.2	UniProtKB/TrEMBL
	ENSCAFT00000095369.1	UniProtKB/TrEMBL
	ENSCAFT00000096028.1	UniProtKB/TrEMBL
	ENSCAFT00000098348.1	UniProtKB/TrEMBL
	ENSCAFT00000105354.1	UniProtKB/TrEMBL
	ENSCAFT00030011954.1	UniProtKB/TrEMBL
	ENSCAFT00030012023.1	UniProtKB/TrEMBL
	ENSCAFT00030012078.1	UniProtKB/TrEMBL
	ENSCAFT00030012160.1	UniProtKB/TrEMBL
	ENSCAFT00030012236.1	UniProtKB/TrEMBL
	ENSCAFT00030012310.1	UniProtKB/TrEMBL
	ENSCAFT00030012411.1	UniProtKB/TrEMBL
	ENSCAFT00030012426.1	UniProtKB/TrEMBL
	ENSCAFT00030012443.1	UniProtKB/TrEMBL
	ENSCAFT00030012455.1	UniProtKB/TrEMBL
	ENSCAFT00040020600.1	UniProtKB/TrEMBL
	ENSCAFT00040020683.1	UniProtKB/TrEMBL
	ENSCAFT00040020784.1	UniProtKB/TrEMBL
	ENSCAFT00040020938.1	UniProtKB/TrEMBL
	ENSCAFT00040020983.1	UniProtKB/TrEMBL
	ENSCAFT00040021017.1	UniProtKB/TrEMBL
	ENSCAFT00040021057.1	UniProtKB/TrEMBL
	ENSCAFT00845031726.1	UniProtKB/TrEMBL
	ENSCAFT00845031820	ENTREZGENE
	ENSCAFT00845031820.1	UniProtKB/TrEMBL
	ENSCAFT00845031956.1	UniProtKB/TrEMBL
	ENSCAFT00845032054.1	UniProtKB/TrEMBL
	ENSCAFT00845032180.1	UniProtKB/TrEMBL
	ENSCAFT00845032291.1	UniProtKB/TrEMBL
	ENSCAFT00845032365.1	UniProtKB/TrEMBL
	ENSCAFT00845032418.1	UniProtKB/TrEMBL
	ENSCAFT00845032450.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.555.10	UniProtKB/TrEMBL
	3.30.505.10	UniProtKB/TrEMBL
	3.30.60.20	UniProtKB/TrEMBL
InterPro	C1-like_sf	UniProtKB/TrEMBL
	Chimaerin_SH2	UniProtKB/TrEMBL
	CHN1/CHN2	UniProtKB/TrEMBL
	DAG/PE-bd	UniProtKB/TrEMBL
	PE/DAG-bd	UniProtKB/TrEMBL
	Rho_GTPase_activation_prot	UniProtKB/TrEMBL
	RhoGAP_chimaerin	UniProtKB/TrEMBL
	RhoGAP_dom	UniProtKB/TrEMBL
	SH2	UniProtKB/TrEMBL
	SH2_dom_sf	UniProtKB/TrEMBL
NCBI Gene	CHN2	ENTREZGENE
PANTHER	BETA-CHIMAERIN	UniProtKB/TrEMBL
	CHIMERIN FAMILY MEMBER	UniProtKB/TrEMBL
Pfam	C1_1	UniProtKB/TrEMBL
	RhoGAP	UniProtKB/TrEMBL
	SH2	UniProtKB/TrEMBL
PIRSF	N-chimaerin	UniProtKB/TrEMBL
PRINTS	DAGPEDOMAIN	UniProtKB/TrEMBL
	SH2DOMAIN	UniProtKB/TrEMBL
PROSITE	RHOGAP	UniProtKB/TrEMBL
	SH2	UniProtKB/TrEMBL
	ZF_DAG_PE_1	UniProtKB/TrEMBL
	ZF_DAG_PE_2	UniProtKB/TrEMBL
SMART	RhoGAP	UniProtKB/TrEMBL
	SH2	UniProtKB/TrEMBL
	SM00109	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48350	UniProtKB/TrEMBL
	SSF55550	UniProtKB/TrEMBL
	SSF57889	UniProtKB/TrEMBL
UniProt	A0A8C0JU01	ENTREZGENE
	A0A8C0MEM8_CANLF	UniProtKB/TrEMBL
	A0A8C0MJE3_CANLF	UniProtKB/TrEMBL
	A0A8C0MJL3_CANLF	UniProtKB/TrEMBL
	A0A8C0MKS8_CANLF	UniProtKB/TrEMBL
	A0A8C0MKT7_CANLF	UniProtKB/TrEMBL
	A0A8C0MRK8_CANLF	UniProtKB/TrEMBL
	A0A8C0RE74_CANLF	UniProtKB/TrEMBL
	A0A8C0S9H2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0SB75_CANLF	UniProtKB/TrEMBL
	A0A8C0YVP0_CANLF	UniProtKB/TrEMBL
	A0A8I3NU16	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3NV36_CANLF	UniProtKB/TrEMBL
	A0A8I3NV41	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3NVT6_CANLF	UniProtKB/TrEMBL
	A0A8I3NZ97_CANLF	UniProtKB/TrEMBL
	A0A8I3P5E9_CANLF	UniProtKB/TrEMBL
	A0A8I3P5M2_CANLF	UniProtKB/TrEMBL
	A0A8I3PB15_CANLF	UniProtKB/TrEMBL
	A0A8I3S0E6_CANLF	UniProtKB/TrEMBL
	A0A8P0P6T8_CANLF	UniProtKB/TrEMBL
	A0A8P0P7U4_CANLF	UniProtKB/TrEMBL
	A0A8P0SQC4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0T6C8_CANLF	UniProtKB/TrEMBL
	A0A8P0T7Z6_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:49738	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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