Chn1 (chimerin 1) - Rat Genome Database

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Gene: Chn1 (chimerin 1) Rattus norvegicus
Analyze
Symbol: Chn1
Name: chimerin 1
RGD ID: 620139
Description: Predicted to enable GTPase activator activity and ephrin receptor binding activity. Predicted to be involved in ephrin receptor signaling pathway; motor neuron axon guidance; and regulation of axonogenesis. Human ortholog(s) of this gene implicated in Duane retraction syndrome. Orthologous to human CHN1 (chimerin 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A-chimaerin; alpha-chimerin; chimerin (chimaerin) 1; N-chimaerin; N-chimerin; NC; rho GTPase-activating protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8378,917,329 - 79,084,040 (-)NCBIGRCr8
mRatBN7.2358,509,822 - 58,676,462 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl358,510,536 - 58,676,490 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx361,903,426 - 62,070,497 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0370,487,079 - 70,654,162 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0368,252,108 - 68,419,189 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0360,512,360 - 60,668,413 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl360,513,077 - 60,611,924 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0366,992,186 - 67,147,012 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4356,144,053 - 56,186,665 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1356,040,424 - 56,083,037 (-)NCBI
Celera358,037,858 - 58,080,474 (-)NCBICelera
Cytogenetic Map3q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Developmental regulation and neuronal expression of the mRNA of rat n-chimaerin, a p21rac GAP:cDNA sequence. Lim HH, etal., Biochem J 1992 Oct 15;287 ( Pt 2):415-22.
4. Developmental regulation and neuronal expression of the mRNA of rat n-chimaerin, a p21rac GAP:cDNA sequence. Lim HH, etal., Biochem J 1992 Oct 15;287 ( Pt 2):415-22.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15483118   PMID:15489334   PMID:17719550   PMID:17785183   PMID:17911252   PMID:21056981   PMID:22369992  


Genomics

Comparative Map Data
Chn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8378,917,329 - 79,084,040 (-)NCBIGRCr8
mRatBN7.2358,509,822 - 58,676,462 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl358,510,536 - 58,676,490 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx361,903,426 - 62,070,497 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0370,487,079 - 70,654,162 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0368,252,108 - 68,419,189 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0360,512,360 - 60,668,413 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl360,513,077 - 60,611,924 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0366,992,186 - 67,147,012 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4356,144,053 - 56,186,665 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1356,040,424 - 56,083,037 (-)NCBI
Celera358,037,858 - 58,080,474 (-)NCBICelera
Cytogenetic Map3q23NCBI
CHN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382174,798,809 - 175,005,381 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2174,798,809 - 175,005,381 (-)EnsemblGRCh38hg38GRCh38
GRCh372175,663,537 - 175,870,109 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362175,372,338 - 175,578,361 (-)NCBINCBI36Build 36hg18NCBI36
Build 342175,489,740 - 175,695,461NCBI
Celera2169,277,589 - 169,483,716 (-)NCBICelera
Cytogenetic Map2q31.1NCBI
HuRef2167,544,975 - 167,750,776 (-)NCBIHuRef
CHM1_12175,670,072 - 175,876,103 (-)NCBICHM1_1
T2T-CHM13v2.02175,287,561 - 175,494,136 (-)NCBIT2T-CHM13v2.0
Chn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39273,441,004 - 73,605,723 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl273,441,004 - 73,605,690 (-)EnsemblGRCm39 Ensembl
GRCm38273,610,660 - 73,775,367 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl273,610,660 - 73,775,346 (-)EnsemblGRCm38mm10GRCm38
MGSCv37273,448,717 - 73,613,403 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36273,411,584 - 73,461,205 (-)NCBIMGSCv36mm8
Celera275,297,418 - 75,408,740 (-)NCBICelera
Cytogenetic Map2C3NCBI
cM Map243.78NCBI
Chn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955449574,407 - 635,566 (+)NCBIChiLan1.0ChiLan1.0
CHN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21377,461,632 - 77,672,824 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B77,476,538 - 77,685,703 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B62,074,405 - 62,283,013 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B179,527,971 - 179,694,524 (-)NCBIpanpan1.1PanPan1.1panPan2
CHN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13618,785,470 - 18,990,409 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3618,786,073 - 18,980,993 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3618,794,209 - 18,999,749 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03618,922,240 - 19,128,093 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3618,921,400 - 19,118,599 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13618,998,481 - 19,204,056 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03618,997,206 - 19,202,881 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03619,107,993 - 19,313,290 (-)NCBIUU_Cfam_GSD_1.0
Chn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303135,953,039 - 136,123,796 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365094,506,311 - 4,678,313 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365094,507,042 - 4,677,681 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1580,730,716 - 80,927,746 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11580,731,243 - 80,927,746 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21589,940,525 - 90,059,474 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CHN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11060,334,829 - 60,540,309 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1060,331,214 - 60,488,785 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040139,071,168 - 139,270,190 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Chn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478711,989,587 - 12,176,925 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Chn1
755 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:146
Count of miRNA genes:95
Interacting mature miRNAs:119
Transcripts:ENSRNOT00000068745
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)32824968773249687Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35378111291609953Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)33068464275684642Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)32824968773249687Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
1582249Bw77Body weight QTL 773.20.0025epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)35318459364655484Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
12879868Am6Aortic mass QTL 60.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)33142640370668733Rat
11565451Bw177Body weight QTL 1770.002body mass (VT:0001259)body weight (CMO:0000012)33142640370668733Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
11565452Kidm57Kidney mass QTL 570.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)33142640370668733Rat
12879866Cm94Cardiac mass QTL 940.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)33142640370668733Rat
12879867Cm95Cardiac mass QTL 950.047heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)33142640370668733Rat
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)34382736490905114Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)35318469289878207Rat
2302055Pia30Pristane induced arthritis QTL 303.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)32793691972936919Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)33945463789115240Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)33370334778196190Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)32846857173468571Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)32846857173468571Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)33945463789115240Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)33068464275684642Rat
1300169Bp177Blood pressure QTL 1772.96arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)33370334761017857Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2302276Bw82Body weight QTL 824.32body mass (VT:0001259)body weight (CMO:0000012)33945463762951183Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)33851780383517803Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32824968773249687Rat
10450804Scl70Serum cholesterol level QTL 704.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)32824968773249687Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)31695470861954708Rat
10450794Scl69Serum cholesterol level QTL 696.30.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)32824968773249687Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
2301400Cm68Cardiac mass QTL 680.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)33142640370668733Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat

Markers in Region
D3Rat39  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2358,539,543 - 58,539,716 (+)MAPPERmRatBN7.2
Rnor_6.0360,542,336 - 60,542,508NCBIRnor6.0
Rnor_5.0367,021,434 - 67,021,606UniSTSRnor5.0
RGSC_v3.4356,173,044 - 56,173,217RGDRGSC3.4
RGSC_v3.4356,173,045 - 56,173,217UniSTSRGSC3.4
RGSC_v3.1356,069,335 - 56,069,642RGD
Celera358,066,862 - 58,067,026UniSTS
SHRSP x BN Map337.2498UniSTS
SHRSP x BN Map337.2498RGD
Cytogenetic Map3q23UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000068745   ⟹   ENSRNOP00000060544
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl358,510,631 - 58,676,208 (-)Ensembl
Rnor_6.0 Ensembl360,513,077 - 60,611,924 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098029   ⟹   ENSRNOP00000093006
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl358,511,155 - 58,676,208 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099938   ⟹   ENSRNOP00000081883
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl358,510,536 - 58,676,200 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000102625   ⟹   ENSRNOP00000082258
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl358,510,536 - 58,676,490 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000102775   ⟹   ENSRNOP00000097347
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl358,510,551 - 58,676,197 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107752   ⟹   ENSRNOP00000083871
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl358,511,275 - 58,676,200 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116234   ⟹   ENSRNOP00000093273
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl358,510,536 - 58,676,490 (-)Ensembl
RefSeq Acc Id: NM_001399177   ⟹   NP_001386106
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8378,917,329 - 79,083,950 (-)NCBI
mRatBN7.2358,509,822 - 58,676,462 (-)NCBI
RefSeq Acc Id: NM_032083   ⟹   NP_114472
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8378,917,329 - 78,960,726 (-)NCBI
mRatBN7.2358,509,822 - 58,553,221 (-)NCBI
Rnor_6.0360,513,088 - 60,555,956 (-)NCBI
Rnor_5.0366,992,186 - 67,147,012 (-)NCBI
RGSC_v3.4356,144,053 - 56,186,665 (-)RGD
Celera358,037,858 - 58,080,474 (-)RGD
Sequence:
RefSeq Acc Id: XM_006234386   ⟹   XP_006234448
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8378,918,043 - 79,049,782 (-)NCBI
mRatBN7.2358,510,410 - 58,642,085 (-)NCBI
Rnor_6.0360,512,360 - 60,642,857 (-)NCBI
Rnor_5.0366,992,186 - 67,147,012 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039105973   ⟹   XP_038961901
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8378,918,043 - 79,075,285 (-)NCBI
mRatBN7.2358,510,410 - 58,676,195 (-)NCBI
RefSeq Acc Id: XM_063284708   ⟹   XP_063140778
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8378,918,043 - 79,031,463 (-)NCBI
RefSeq Acc Id: XM_063284709   ⟹   XP_063140779
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8378,918,043 - 78,960,762 (-)NCBI
RefSeq Acc Id: XR_010064703
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8378,987,371 - 79,084,040 (-)NCBI
RefSeq Acc Id: NP_114472   ⟸   NM_032083
- Peptide Label: isoform 2
- UniProtKB: P30337 (UniProtKB/Swiss-Prot),   Q505J4 (UniProtKB/Swiss-Prot),   A6HMA4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234448   ⟸   XM_006234386
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A036 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000060544   ⟸   ENSRNOT00000068745
RefSeq Acc Id: XP_038961901   ⟸   XM_039105973
- Peptide Label: isoform X2
- UniProtKB: A0A8I6ASS0 (UniProtKB/TrEMBL),   A0A8I6AHR6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000082258   ⟸   ENSRNOT00000102625
Ensembl Acc Id: ENSRNOP00000083871   ⟸   ENSRNOT00000107752
Ensembl Acc Id: ENSRNOP00000081883   ⟸   ENSRNOT00000099938
Ensembl Acc Id: ENSRNOP00000093273   ⟸   ENSRNOT00000116234
Ensembl Acc Id: ENSRNOP00000093006   ⟸   ENSRNOT00000098029
Ensembl Acc Id: ENSRNOP00000097347   ⟸   ENSRNOT00000102775
RefSeq Acc Id: NP_001386106   ⟸   NM_001399177
- Peptide Label: isoform 1
RefSeq Acc Id: XP_063140778   ⟸   XM_063284708
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063140779   ⟸   XM_063284709
- Peptide Label: isoform X4
Protein Domains
Phorbol-ester/DAG-type   Rho-GAP   SH2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P30337-F1-model_v2 AlphaFold P30337 1-334 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620139 AgrOrtholog
BioCyc Gene G2FUF-49363 BioCyc
Ensembl Genes ENSRNOG00000017939 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000068745.4 UniProtKB/TrEMBL
  ENSRNOT00000098029.1 UniProtKB/TrEMBL
  ENSRNOT00000099938.1 UniProtKB/TrEMBL
  ENSRNOT00000102625.1 UniProtKB/TrEMBL
  ENSRNOT00000102775.1 UniProtKB/TrEMBL
  ENSRNOT00000107752.1 UniProtKB/TrEMBL
  ENSRNOT00000116234.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.555.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/TrEMBL
  3.30.60.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7315609 IMAGE-MGC_LOAD
InterPro C1-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chimaerin_SH2 UniProtKB/TrEMBL
  CHN1/CHN2 UniProtKB/TrEMBL
  DAG/PE-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PE/DAG-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rho-type_GAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGAP_chimaerin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
KEGG Report rno:84030 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105381 IMAGE-MGC_LOAD
NCBI Gene 84030 ENTREZGENE
PANTHER CHIMERIN FAMILY MEMBER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  N-CHIMAERIN UniProtKB/Swiss-Prot
  N-CHIMAERIN UniProtKB/TrEMBL
  N-CHIMAERIN UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
PhenoGen Chn1 PhenoGen
PIRSF N-chimaerin UniProtKB/TrEMBL
PRINTS DAGPEDOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE RHOGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000017939 RatGTEx
SMART RhoGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SM00109 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48350 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
  SSF57889 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A140TAJ1_RAT UniProtKB/TrEMBL
  A0A8I5ZU15_RAT UniProtKB/TrEMBL
  A0A8I5ZUM2_RAT UniProtKB/TrEMBL
  A0A8I6A036 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AHR6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AID6_RAT UniProtKB/TrEMBL
  A0A8I6ASS0 ENTREZGENE, UniProtKB/TrEMBL
  A6HMA4 ENTREZGENE, UniProtKB/TrEMBL
  CHIN_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q505J4 ENTREZGENE
UniProt Secondary Q505J4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-25 Chn1  chimerin 1  Chn1  chimerin (chimaerin) 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Chn1  chimerin (chimaerin) 1      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Chn1  chimerin (chimaerin) 1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_homology 97% amino acid identity with human homolog 724724
gene_protein 334 amino acids; 38.2 kDa; pI 8.04 724724