Chn1 (chimerin 1) - Rat Genome Database

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Gene: Chn1 (chimerin 1) Rattus norvegicus
Analyze
Symbol: Chn1
Name: chimerin 1
RGD ID: 620139
Description: Predicted to enable GTPase activator activity and ephrin receptor binding activity. Predicted to be involved in ephrin receptor signaling pathway; motor neuron axon guidance; and regulation of axonogenesis. Human ortholog(s) of this gene implicated in Duane retraction syndrome 2. Orthologous to human CHN1 (chimerin 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A-chimaerin; alpha-chimerin; chimerin (chimaerin) 1; N-chimaerin; N-chimerin; NC; rho GTPase-activating protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8378,917,329 - 79,084,040 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl378,917,329 - 79,084,197 (-)EnsemblGRCr8
mRatBN7.2358,509,822 - 58,676,462 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl358,510,536 - 58,676,490 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx361,903,426 - 62,070,497 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0370,487,079 - 70,654,162 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0368,252,108 - 68,419,189 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0360,512,360 - 60,668,413 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl360,513,077 - 60,611,924 (-)Ensemblrn6Rnor6.0
Rnor_5.0366,992,186 - 67,147,012 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4356,144,053 - 56,186,665 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera358,037,858 - 58,080,474 (-)NCBICelera
RGSC_v3.1356,040,424 - 56,083,037 (-)NCBI
Cytogenetic Map3q23NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Developmental regulation and neuronal expression of the mRNA of rat n-chimaerin, a p21rac GAP:cDNA sequence. Lim HH, etal., Biochem J 1992 Oct 15;287 ( Pt 2):415-22.
4. Developmental regulation and neuronal expression of the mRNA of rat n-chimaerin, a p21rac GAP:cDNA sequence. Lim HH, etal., Biochem J 1992 Oct 15;287 ( Pt 2):415-22.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15483118   PMID:15489334   PMID:17719550   PMID:17785183   PMID:17911252   PMID:21056981   PMID:22369992  


Genomics

Comparative Map Data
Chn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8378,917,329 - 79,084,040 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl378,917,329 - 79,084,197 (-)EnsemblGRCr8
mRatBN7.2358,509,822 - 58,676,462 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl358,510,536 - 58,676,490 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx361,903,426 - 62,070,497 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0370,487,079 - 70,654,162 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0368,252,108 - 68,419,189 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0360,512,360 - 60,668,413 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl360,513,077 - 60,611,924 (-)Ensemblrn6Rnor6.0
Rnor_5.0366,992,186 - 67,147,012 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4356,144,053 - 56,186,665 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera358,037,858 - 58,080,474 (-)NCBICelera
RGSC_v3.1356,040,424 - 56,083,037 (-)NCBI
Cytogenetic Map3q23NCBI
CHN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382174,798,809 - 175,005,381 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2174,798,809 - 175,005,381 (-)Ensemblhg38GRCh38
GRCh372175,663,537 - 175,870,109 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362175,372,338 - 175,578,361 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342175,489,740 - 175,695,461NCBI
Celera2169,277,589 - 169,483,716 (-)NCBICelera
Cytogenetic Map2q31.1NCBI
HuRef2167,544,975 - 167,750,776 (-)NCBIHuRef
CHM1_12175,670,072 - 175,876,103 (-)NCBICHM1_1
T2T-CHM13v2.02175,287,561 - 175,494,136 (-)NCBIT2T-CHM13v2.0
Chn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39273,441,004 - 73,605,723 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl273,441,004 - 73,605,690 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38273,610,660 - 73,775,367 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl273,610,660 - 73,775,346 (-)Ensemblmm10GRCm38
MGSCv37273,448,717 - 73,613,403 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36273,411,584 - 73,461,205 (-)NCBIMGSCv36mm8
Celera275,297,418 - 75,408,740 (-)NCBICelera
Cytogenetic Map2C3NCBI
cM Map243.78NCBI
Chn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955449574,407 - 635,566 (+)NCBIChiLan1.0ChiLan1.0
CHN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21377,461,632 - 77,672,824 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B77,476,538 - 77,685,703 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B62,074,405 - 62,283,013 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B179,527,971 - 179,694,524 (-)NCBIPanPan1.1PanPan1.1panPan2
CHN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13618,785,470 - 18,990,409 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3618,786,073 - 18,980,993 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3618,794,209 - 18,999,749 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03618,922,240 - 19,128,093 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3618,921,400 - 19,118,599 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13618,998,481 - 19,204,056 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03618,997,206 - 19,202,881 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03619,107,993 - 19,313,290 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Chn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303135,953,039 - 136,123,796 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365094,506,311 - 4,678,313 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365094,507,042 - 4,677,681 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1580,730,716 - 80,927,746 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11580,731,243 - 80,927,746 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21589,940,525 - 90,059,474 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CHN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11060,334,829 - 60,540,309 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1060,331,214 - 60,488,785 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040139,071,168 - 139,270,190 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Chn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478711,989,587 - 12,176,925 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Chn1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1550,975,852 - 51,128,819 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Chn1
1009 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:146
Count of miRNA genes:95
Interacting mature miRNAs:119
Transcripts:ENSRNOT00000068745
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)351490129111359995Rat
1358293Bw38Body weight QTL 3860.0000031body mass (VT:0001259)body weight (CMO:0000012)374364268119364268Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)373592611110333156Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)35986366387321459Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)373592512136118980Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)35365182698651826Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)34887661993876619Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)34887661993876619Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)33540319997383526Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)349872657138829559Rat
631832Sach1Saccharin preference QTL 12.70.02consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)34790417292904172Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)35986366387321459Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)35109256196092561Rat
1300169Bp177Blood pressure QTL 1772.96arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)33642511681425116Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)34865774493657744Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)370845569136091483Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)33779691982796919Rat
2302276Bw82Body weight QTL 824.32body mass (VT:0001259)body weight (CMO:0000012)35986366383358329Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)358925062103925062Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)370311536115311536Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)34865774493657744Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)35076614595766145Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)35109256196092561Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)35076614595766145Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)336721849110333156Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)34865774493657744Rat
1582249Bw77Body weight QTL 773.20.0025epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)37359251285062403Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)342158111124558371Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
2325840Bp345Blood pressure QTL 3450.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)33870893183708931Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)34865774493657744Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)33736373482363734Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)33610140381101403Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)34865774493657744Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)342158111124558371Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat

Markers in Region
D3Rat39  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8378,947,048 - 78,947,221 (+)Marker Load Pipeline
mRatBN7.2358,539,543 - 58,539,716 (+)MAPPERmRatBN7.2
Rnor_6.0360,542,336 - 60,542,508NCBIRnor6.0
Rnor_5.0367,021,434 - 67,021,606UniSTSRnor5.0
RGSC_v3.4356,173,044 - 56,173,217RGDRGSC3.4
RGSC_v3.4356,173,045 - 56,173,217UniSTSRGSC3.4
Celera358,066,862 - 58,067,026UniSTS
RGSC_v3.1356,069,335 - 56,069,642RGD
SHRSP x BN Map337.2498UniSTS
SHRSP x BN Map337.2498RGD
Cytogenetic Map3q23UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000068745   ⟹   ENSRNOP00000060544
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl378,917,329 - 79,083,679 (-)Ensembl
mRatBN7.2 Ensembl358,510,631 - 58,676,208 (-)Ensembl
Rnor_6.0 Ensembl360,513,077 - 60,611,924 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098029   ⟹   ENSRNOP00000093006
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl378,917,329 - 79,083,809 (-)Ensembl
mRatBN7.2 Ensembl358,511,155 - 58,676,208 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099938   ⟹   ENSRNOP00000081883
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl378,917,329 - 79,083,792 (-)Ensembl
mRatBN7.2 Ensembl358,510,536 - 58,676,200 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000102625   ⟹   ENSRNOP00000082258
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl378,917,329 - 79,084,197 (-)Ensembl
mRatBN7.2 Ensembl358,510,536 - 58,676,490 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000102775   ⟹   ENSRNOP00000097347
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl378,917,329 - 79,083,664 (-)Ensembl
mRatBN7.2 Ensembl358,510,551 - 58,676,197 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107752   ⟹   ENSRNOP00000083871
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl378,917,329 - 79,072,342 (-)Ensembl
mRatBN7.2 Ensembl358,511,275 - 58,676,200 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116234   ⟹   ENSRNOP00000093273
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl378,917,329 - 79,084,140 (-)Ensembl
mRatBN7.2 Ensembl358,510,536 - 58,676,490 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000140416   ⟹   ENSRNOP00000098759
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl378,917,329 - 79,049,819 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000147108   ⟹   ENSRNOP00000112782
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl378,917,329 - 79,083,950 (-)Ensembl
RefSeq Acc Id: NM_001399177   ⟹   NP_001386106
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8378,917,329 - 79,083,950 (-)NCBI
mRatBN7.2358,509,822 - 58,676,462 (-)NCBI
RefSeq Acc Id: NM_032083   ⟹   NP_114472
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8378,917,329 - 78,960,726 (-)NCBI
mRatBN7.2358,509,822 - 58,553,221 (-)NCBI
Rnor_6.0360,513,088 - 60,555,956 (-)NCBI
Rnor_5.0366,992,186 - 67,147,012 (-)NCBI
RGSC_v3.4356,144,053 - 56,186,665 (-)RGD
Celera358,037,858 - 58,080,474 (-)RGD
Sequence:
RefSeq Acc Id: XM_006234386   ⟹   XP_006234448
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8378,918,043 - 79,049,782 (-)NCBI
mRatBN7.2358,510,410 - 58,642,085 (-)NCBI
Rnor_6.0360,512,360 - 60,642,857 (-)NCBI
Rnor_5.0366,992,186 - 67,147,012 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039105973   ⟹   XP_038961901
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8378,918,043 - 79,075,285 (-)NCBI
mRatBN7.2358,510,410 - 58,676,195 (-)NCBI
RefSeq Acc Id: XM_063284708   ⟹   XP_063140778
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8378,918,043 - 79,031,463 (-)NCBI
RefSeq Acc Id: XM_063284709   ⟹   XP_063140779
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8378,918,043 - 78,960,762 (-)NCBI
RefSeq Acc Id: XR_010064703
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8378,987,371 - 79,084,040 (-)NCBI
RefSeq Acc Id: NP_114472   ⟸   NM_032083
- Peptide Label: isoform 2
- UniProtKB: P30337 (UniProtKB/Swiss-Prot),   Q505J4 (UniProtKB/Swiss-Prot),   A6HMA4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234448   ⟸   XM_006234386
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A036 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000060544   ⟸   ENSRNOT00000068745
RefSeq Acc Id: XP_038961901   ⟸   XM_039105973
- Peptide Label: isoform X2
- UniProtKB: A0A8I6ASS0 (UniProtKB/TrEMBL),   A0A8I6AHR6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000082258   ⟸   ENSRNOT00000102625
Ensembl Acc Id: ENSRNOP00000083871   ⟸   ENSRNOT00000107752
Ensembl Acc Id: ENSRNOP00000081883   ⟸   ENSRNOT00000099938
Ensembl Acc Id: ENSRNOP00000093273   ⟸   ENSRNOT00000116234
Ensembl Acc Id: ENSRNOP00000093006   ⟸   ENSRNOT00000098029
Ensembl Acc Id: ENSRNOP00000097347   ⟸   ENSRNOT00000102775
RefSeq Acc Id: NP_001386106   ⟸   NM_001399177
- Peptide Label: isoform 1
- UniProtKB: A0A8I6A036 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140778   ⟸   XM_063284708
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A036 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140779   ⟸   XM_063284709
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000112782   ⟸   ENSRNOT00000147108
Ensembl Acc Id: ENSRNOP00000098759   ⟸   ENSRNOT00000140416
Protein Domains
Phorbol-ester/DAG-type   Rho-GAP   SH2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P30337-F1-model_v2 AlphaFold P30337 1-334 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620139 AgrOrtholog
BioCyc Gene G2FUF-49363 BioCyc
Ensembl Genes ENSRNOG00000017939 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000068745 ENTREZGENE
  ENSRNOT00000099938 ENTREZGENE
  ENSRNOT00000102775 ENTREZGENE
  ENSRNOT00000140416 ENTREZGENE
Gene3D-CATH 1.10.555.10 UniProtKB/Swiss-Prot
  3.30.60.20 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7315609 IMAGE-MGC_LOAD
InterPro C1-like_sf UniProtKB/Swiss-Prot
  DAG/PE-bd UniProtKB/Swiss-Prot
  PE/DAG-bd UniProtKB/Swiss-Prot
  Rho-type_GAP UniProtKB/Swiss-Prot
  Rho_GTPase_activation_prot UniProtKB/Swiss-Prot
  RhoGAP_chimaerin UniProtKB/Swiss-Prot
  RhoGAP_dom UniProtKB/Swiss-Prot
KEGG Report rno:84030 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105381 IMAGE-MGC_LOAD
NCBI Gene 84030 ENTREZGENE
PANTHER CHIMERIN FAMILY MEMBER UniProtKB/Swiss-Prot
  N-CHIMAERIN UniProtKB/Swiss-Prot
Pfam C1_1 UniProtKB/Swiss-Prot
  RhoGAP UniProtKB/Swiss-Prot
PhenoGen Chn1 PhenoGen
PRINTS DAGPEDOMAIN UniProtKB/Swiss-Prot
PROSITE RHOGAP UniProtKB/Swiss-Prot
  ZF_DAG_PE_1 UniProtKB/Swiss-Prot
  ZF_DAG_PE_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000017939 RatGTEx
SMART RhoGAP UniProtKB/Swiss-Prot
  SM00109 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48350 UniProtKB/Swiss-Prot
  SSF57889 UniProtKB/Swiss-Prot
UniProt A0A140TAJ1_RAT UniProtKB/TrEMBL
  A0A8I5ZU15_RAT UniProtKB/TrEMBL
  A0A8I5ZUM2_RAT UniProtKB/TrEMBL
  A0A8I6A036 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AHR6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AID6_RAT UniProtKB/TrEMBL
  A0A8I6ASS0 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0KWI1_RAT UniProtKB/TrEMBL
  A0ABK0M968_RAT UniProtKB/TrEMBL
  A6HMA4 ENTREZGENE, UniProtKB/TrEMBL
  CHIN_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q505J4 ENTREZGENE
UniProt Secondary Q505J4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-25 Chn1  chimerin 1  Chn1  chimerin (chimaerin) 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Chn1  chimerin (chimaerin) 1      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Chn1  chimerin (chimaerin) 1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_homology 97% amino acid identity with human homolog 724724
gene_protein 334 amino acids; 38.2 kDa; pI 8.04 724724