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Gene: Zic1 (Zic family zinc finger 1) Rattus norvegicus

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Symbol:

Zic1

Name:

Zic family zinc finger 1 (Ensembl:Zic family member 1)

RGD ID:

620110

Description:

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including central nervous system development; positive regulation of protein import into nucleus; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within adult walking behavior. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Dandy-Walker syndrome and craniosynostosis 6. Orthologous to human ZIC1 (Zic family member 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Zic family member 1; Zic family member 1 (odd-paired homolog, Drosophila); zic protein member 1; zinc finger protein of the cerebellum 1; zinc finger protein ZIC 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ZIC1 (Zic family zinc finger 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Zic1 (zinc finger protein of the cerebellum 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Zic1 (Zic family zinc finger 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ZIC1 (Zic family zinc finger 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ZIC1 (Zic family zinc finger 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Zic1 (Zic family zinc finger 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ZIC1 (Zic family member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ZIC1 (Zic family zinc finger 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Zic1 (Zic family zinc finger 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Zic1 (Zic family zinc finger 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ZIC1 (Zic family zinc finger 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Zic1 (zinc finger protein of the cerebellum 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	zic1 (zic family member 1 (odd-paired homolog, Drosophila))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ref-2	Alliance	DIOPT (InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ref-2	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	opa	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	opa	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	LOC100493456	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	100,785,282 - 100,797,716 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	100,787,789 - 100,792,427 (-)	Ensembl				GRCr8
mRatBN7.2	8	91,908,548 - 91,918,020 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	91,908,576 - 91,912,731 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	97,587,773 - 97,591,212 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	95,787,021 - 95,790,460 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	93,600,935 - 93,604,373 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	98,733,715 - 98,738,960 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	98,734,295 - 98,738,446 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	98,226,542 - 98,229,980 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	96,314,692 - 96,318,130 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	91,436,069 - 91,439,507 (-)	NCBI		Celera
RGSC_v3.1	8	96,334,146 - 96,337,585 (-)	NCBI
Cytogenetic Map	8	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

craniosynostosis (ISO)

craniosynostosis 6 (ISO)

Dandy-Walker syndrome (ISO,ISS)

genetic disease (ISO)

Joubert syndrome (ISS)

STRUCTURAL BRAIN ANOMALIES WITH IMPAIRED INTELLECTUAL DEVELOPMENT AND CRANIOSYNOSTOSIS (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(S)-nicotine (ISO)

17alpha-ethynylestradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

3,3',5,5'-tetrabromobisphenol A (ISO)

4,4'-sulfonyldiphenol (ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

choline (ISO)

cisplatin (ISO)

coumestrol (ISO)

cyclophosphamide (ISO)

decabromodiphenyl ether (ISO)

dimethylarsinic acid (EXP)

dorsomorphin (ISO)

entinostat (ISO)

ethanol (ISO)

fenvalerate (EXP)

folic acid (ISO)

fonofos (ISO)

iron dichloride (ISO)

L-methionine (ISO)

methylmercury chloride (ISO)

morphine (ISO)

nickel atom (ISO)

nicotine (ISO)

okadaic acid (ISO)

p-chloromercuribenzoic acid (ISO)

panobinostat (ISO)

parathion (ISO)

piperonyl butoxide (EXP)

SB 431542 (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

terbufos (ISO)

testosterone enanthate (ISO)

Tetrachlorobisphenol A (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adult walking behavior (ISO)

biological_process (ND)

brain development (IEA,ISO)

central nervous system development (ISO)

forebrain development (IEA,ISO)

gene expression (IEA,ISO)

hippocampus development (IEA,ISO)

maintenance of cell number (IEA,ISO)

olfactory bulb development (IEA,ISO)

pattern specification process (IEA,ISO)

positive regulation of DNA-templated transcription (IEA,ISO)

positive regulation of protein import into nucleus (IEA,ISO)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

regulation of smoothened signaling pathway (IEA,ISO)

regulation of transcription by RNA polymerase II (IEA)

spinal cord development (IEA,ISO)

Cellular Component

cytoplasm (IEA,ISO)

nucleoplasm (ISO)

nucleus (IEA,ISO)

Molecular Function

DNA binding (IEA)

DNA-binding transcription activator activity, RNA polymerase II-specific (IEA,ISO)

DNA-binding transcription factor activity (IEA,ISO)

metal ion binding (IEA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IEA,ISO)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (IEA,ISO)

sequence-specific double-stranded DNA binding (ISO)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Zic2 controls cerebellar development in cooperation with Zic1.	Aruga J, etal., J Neurosci 2002 Jan 1;22(1):218-25.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Heterozygous deletion of the linked genes ZIC1 and ZIC4 is involved in Dandy-Walker malformation.	Grinberg I, etal., Nat Genet. 2004 Oct;36(10):1053-5. Epub 2004 Aug 29.
5.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
6.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
7.	GOA pipeline	RGD automated data pipeline
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
9.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:7931345	PMID:8542595	PMID:9070329	PMID:9412507	PMID:11053430	PMID:11238441	PMID:11944941	PMID:15207726	PMID:15465018	PMID:18298960	PMID:25907855

Genomics

Comparative Map Data

Zic1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	100,785,282 - 100,797,716 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	100,787,789 - 100,792,427 (-)	Ensembl				GRCr8
mRatBN7.2	8	91,908,548 - 91,918,020 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	91,908,576 - 91,912,731 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	97,587,773 - 97,591,212 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	95,787,021 - 95,790,460 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	93,600,935 - 93,604,373 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	98,733,715 - 98,738,960 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	98,734,295 - 98,738,446 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	98,226,542 - 98,229,980 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	96,314,692 - 96,318,130 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	91,436,069 - 91,439,507 (-)	NCBI		Celera
RGSC_v3.1	8	96,334,146 - 96,337,585 (-)	NCBI
Cytogenetic Map	8	q31	NCBI

ZIC1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	147,409,365 - 147,416,719 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	147,393,422 - 147,510,293 (+)	Ensembl			hg38	GRCh38
GRCh37	3	147,127,152 - 147,134,506 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	148,609,871 - 148,617,196 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	3	148,609,878 - 148,615,046	NCBI
Celera	3	145,539,633 - 145,546,958 (+)	NCBI		Celera
Cytogenetic Map	3	q24	NCBI
HuRef	3	144,503,350 - 144,510,663 (+)	NCBI		HuRef
CHM1_1	3	147,090,188 - 147,097,518 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	150,164,618 - 150,171,972 (+)	NCBI		T2T-CHM13v2.0

Zic1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	91,240,111 - 91,250,136 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	91,240,111 - 91,247,863 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	9	91,358,058 - 91,365,768 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	91,358,058 - 91,365,810 (-)	Ensembl			mm10	GRCm38
MGSCv37	9	91,255,183 - 91,260,637 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	9	91,158,250 - 91,163,704 (-)	NCBI		MGSCv36	mm8
Celera	9	90,951,458 - 90,959,662 (-)	NCBI		Celera
Cytogenetic Map	9	E3.2	NCBI
cM Map	9	48.26	NCBI

Zic1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955474	10,029,174 - 10,033,380 (-)	Ensembl
ChiLan1.0	NW_004955474	10,029,226 - 10,033,104 (-)	NCBI	ChiLan1.0	ChiLan1.0

ZIC1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	145,305,012 - 145,312,262 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	145,310,546 - 145,316,993 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	144,437,075 - 144,443,516 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	152,019,288 - 152,024,497 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	152,019,013 - 152,024,502 (+)	Ensembl			panPan2	panpan1.1

ZIC1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Dog10K_Boxer_Tasha	23	42,405,942 - 42,410,126 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	43,154,161 - 43,158,357 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	23	43,154,177 - 43,162,933 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	23	42,751,244 - 42,755,412 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	42,803,713 - 42,807,873 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	43,055,395 - 43,059,590 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Zic1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	81,731,682 - 81,736,232 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936519	7,994,455 - 8,002,487 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936519	7,997,824 - 8,001,614 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZIC1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	87,745,552 - 87,750,192 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	87,740,769 - 87,750,258 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	95,427,405 - 95,431,044 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ZIC1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	43,280,429 - 43,285,674 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	43,281,433 - 43,284,948 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666041	16,147,496 - 16,153,069 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Zic1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	24,440,192 - 24,448,421 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624730	24,440,717 - 24,444,663 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Zic1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	8	83,101,629 - 83,106,418 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Zic1
71 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	29
Count of miRNA genes:	25
Interacting mature miRNAs:	27
Transcripts:	ENSRNOT00000019860
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
12879878	Bw183	Body weight QTL 183		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	8	62848139	107848139	Rat
1300177	Cm2	Cardiac mass QTL 2	3.65		heart mass (VT:0007028)	heart weight (CMO:0000017)	8	63141536	109261840	Rat
1549909	Stresp11	Stress response QTL 11	6.83	0.0019	stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	8	82352698	127352698	Rat
1549908	Neudeg1	Neurodegradation QTL 1	5.5	0	nervous system integrity trait (VT:0010566)	logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)	8	58337123	103337123	Rat
12879879	Cm99	Cardiac mass QTL 99		0.001	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	62848139	107848139	Rat
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	49849908	118871671	Rat
9590292	Uminl3	Urine mineral level QTL 3	3.62	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	8	80768445	125768445	Rat
1331804	Cm30	Cardiac mass QTL 30	3.77443		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	8	62970527	107970527	Rat
1578769	Uae31	Urinary albumin excretion QTL 31	3.3	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	39106363	103375781	Rat
12879880	Cm100	Cardiac mass QTL 100		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	8	62848139	107848139	Rat
12879881	Cm101	Cardiac mass QTL 101		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	8	62848139	107848139	Rat
12879882	Am8	Aortic mass QTL 8		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	8	62848139	107848139	Rat
12879883	Kidm65	Kidney mass QTL 65		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	8	62848139	107848139	Rat
71120	Niddm21	Non-insulin dependent diabetes mellitus QTL 21	3.73		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	8	66992095	111992095	Rat
8693654	Alc32	Alcohol consumption QTL 32	2	0.755	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	8	97492344	116428905	Rat
1358912	Bw51	Body weight QTL 51	2.95		body mass (VT:0001259)	body weight (CMO:0000012)	8	60248093	105248093	Rat
1578765	Klgr1	Kidney lesion grade QTL 1	3.3	0.0001	kidney morphology trait (VT:0002135)	organ lesion measurement (CMO:0000677)	8	39106363	103375781	Rat
634332	Pia18	Pristane induced arthritis QTL 18	4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	84192326	132782436	Rat
1300171	Bp184	Blood pressure QTL 184	3.66		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	8	79394435	132782436	Rat
1578755	Pur5	Proteinuria QTL 5	3.3	0.0001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	8	39106258	103375958	Rat
2313400	Anxrr25	Anxiety related response QTL 25			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	8	98145073	122898010	Rat
631210	Bw3	Body weight QTL3	5.9		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	8	61019838	121662124	Rat
2293697	Bmd39	Bone mineral density QTL 39			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	8	62848139	107848139	Rat
8662823	Vetf5	Vascular elastic tissue fragility QTL 5	1.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	8	63404444	108404444	Rat
1358896	Bp262	Blood pressure QTL 262	2.89		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	35464071	107982864	Rat
1331837	Bw23	Body weight QTL 23	4.19	0.00007	body mass (VT:0001259)	body weight (CMO:0000012)	8	55428416	107963099	Rat
1331838	Niddm61	Non-insulin dependent diabetes mellitus QTL 61	3.53	0.0004	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	8	62963099	107963099	Rat
8694446	Bw170	Body weight QTL 170	12.07	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	8	80768445	125768445	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	70041301	121080908	Rat
1331769	Rf39	Renal function QTL 39	3.871		urine output (VT:0003620)	timed urine volume (CMO:0000260)	8	50763951	107970527	Rat
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	68690349	119799881	Rat
10450865	Bw175	Body weight QTL 175	4.1		total fat pad mass (VT:0015008)	adipose tissue molecular composition measurement (CMO:0000484)	8	84192326	129192326	Rat
1358907	Cm40	Cardiac mass QTL 40	1.89		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	35464071	107982864	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	55428333	127966348	Rat
2316950	Scl66	Serum cholesterol level QTL 66	4.1		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	39106363	114525825	Rat
2300181	Bmd55	Bone mineral density QTL 55	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	85348065	130348065	Rat
724540	Uae8	Urinary albumin excretion QTL 8	5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	8	39106258	103375958	Rat
10402857	Bp380	Blood pressure QTL 380		0.95	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	62848139	107848139	Rat
1358892	Kidm26	Kidney mass QTL 26	3.69		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	8	35464071	107982864	Rat
2301402	Bp316	Blood pressure QTL 316		0.005	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	62848139	107848139	Rat
631664	Hcar3	Hepatocarcinoma resistance QTL 3	2.9	0.0005	liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	8	62982864	107982864	Rat
8694200	Abfw4	Abdominal fat weight QTL 4	9.07	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	8	80768445	125768445	Rat
8694392	Bw161	Body weight QTL 161	8.06	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	8	80768445	125768445	Rat
61437	Cia6	Collagen induced arthritis QTL 6			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	91340911	131690273	Rat

Markers in Region

UniSTS:466091

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	8	100,788,884 - 100,789,739 (+)	Marker Load Pipeline
mRatBN7.2	8	91,909,138 - 91,909,993 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	98,734,854 - 98,735,708	NCBI	Rnor6.0
Rnor_5.0	8	98,226,637 - 98,227,491	UniSTS	Rnor5.0
RGSC_v3.4	8	96,314,787 - 96,315,641	UniSTS	RGSC3.4
Celera	8	91,436,164 - 91,437,018	UniSTS
Cytogenetic Map	8	q31	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
5	10	9	142	30	30	18	7	18	6	80	36	9	124	13	49	12	9	9

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_022677	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008766454	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082089	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF221839	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000019860 ⟹ ENSRNOP00000019860

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	100,787,789 - 100,792,427 (-)	Ensembl
mRatBN7.2 Ensembl	8	91,908,576 - 91,912,731 (-)	Ensembl
Rnor_6.0 Ensembl	8	98,734,295 - 98,738,446 (-)	Ensembl

RefSeq Acc Id:

NM_022677 ⟹ NP_073168

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	100,788,790 - 100,792,228 (-)	NCBI
mRatBN7.2	8	91,909,044 - 91,912,482 (-)	NCBI
Rnor_6.0	8	98,734,759 - 98,738,197 (-)	NCBI
Rnor_5.0	8	98,226,542 - 98,229,980 (-)	NCBI
RGSC_v3.4	8	96,314,692 - 96,318,130 (-)	RGD
Celera	8	91,436,069 - 91,439,507 (-)	RGD

Sequence:

show sequence

ATGCTCCTGGACGCCGGACCCCAGTATCCAGCGATCGGTGTGACCACCTTTGGTGCATCCCGGC
ACCACTCGGCGGGCGACGTGGCCGAAAGAGACGTGGGCCTGGGTATCAACCCGTTCGCCGACGG
CATGGGCGCCTTCAAGCTCAACCCCAGTTCGCACGAACTGGCCTCGGCCGGCCAGACAGCCTTC
ACGTCGCAGGCTCCGGGCTACGCCGCTGCCGCGGCCCTGGGCCACCATCACCACCCCGGCCACG
TCGGCTCCTACTCCAGCGCTGCTTTCAATTCTACCCGGGACTTTCTGTTCCGCAACCGGGGCTT
CGGCGACGCGGCGGCGGCAGCTAGCGCCCAGCACAGTCTCTTCGCTGCTTCGGCCGGCGGTTTC
GGGGGCCCACACGGCCATACGGACGCCGCGGGCCACCTTCTTTTTTCTGGGCTTCACGAGCAGG
CGGCCGGCCACGCTTCGCCCAACGTGGTCAACGGGCAGATGCGGCTAGGTTTCTCCGGGGACAT
GTACCCACGGCCGGAACAGTACGGCCAGGTGACCAGCCCGCGATCCGAGCACTATGCCGCACCG
CAGCTTCACGGCTATGGGCCCATGAACGTGAACATGGCTGCACACCACGGCGCTGGAGCCTTCT
TCCGCTATATGCGCCAACCCATCAAGCAAGAGCTTATCTGTAAATGGATCGAGCCGGAGCAGCT
GGCCAACCCCAAAAAGTCCTGCAACAAAACTTTCAGCACCATGCACGAGCTGGTCACGCACGTC
ACGGTGGAGCACGTCGGCGGCCCAGAGCAGAGCAACCACATCTGCTTCTGGGAGGAGTGTCCAC
GCGAGGGCAAGCCCTTCAAAGCCAAATACAAACTGGTCAACCACATCCGCGTGCATACGGGCGA
AAAGCCTTTTCCCTGCCCGTTTCCTGGCTGCGGCAAGGTTTTCGCACGTTCAGAGAACCTCAAG
ATCCACAAAAGGACGCACACAGGGGAGAAGCCCTTCAAGTGCGAGTTCGAGGGCTGCGACCGGC
GCTTCGCCAACAGCAGCGACCGCAAGAAGCACATGCACGTGCACACTAGCGACAAGCCCTACCT
TTGCAAGATGTGCGATAAGTCCTACACGCACCCCAGCTCTCTGCGCAAACACATGAAGGTCCAT
GAGTCCTCTTCTCAGGGCTCACAGCCTTCGCCCGCCGCCAGCTCGGGGTATGAATCGTCCACGC
CACCCACCATCGTGTCTCCCACCACAGACAACCCGACCACCAGCTCCATGTCGCCCTCTTCCTC
CGCGGTCCACCACACAGCCGGCCACAGCGCGCTCTCTTCCAATTTTAACGAATGGTACGTTTAA

hide sequence

RefSeq Acc Id:

XM_008766454 ⟹ XP_008764676

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	100,785,282 - 100,793,264 (-)	NCBI
mRatBN7.2	8	91,908,548 - 91,913,505 (-)	NCBI
Rnor_6.0	8	98,733,715 - 98,738,960 (-)	NCBI

Sequence:

show sequence

GGGGGGACGACGGTGTCGTCCTTTCAATTCATTTATCTGCAGGAATGATTGCTGCTATCAGTCT
CGCGCTCACCGCCCGGCTGAGGAGCCTTGACTCGAGGCCCTCTCGGCAGAGACTGAGCGGCGAG
AAAGTGAGAGCCCGGCCGGCGCGGTTCGAGCGGCTGACGCCGGAGCCCGCCTTCTACCGGCCGG
CAGTCACCTCGCTTGCCTGCCTTTGGCCGGGCGGGTGCCGGCTAGCGCCTGGCCACTGCCTGCT
GGCTGAGACTTCGTTAGGTGGGTCGACTCCCCCTCCCTCCTCCTCTTCTTCCTCCTCTTCCTCC
GCCTCCCATTTCTCCTCCTCCTCCTGATCTTCCCTCCTTGGCGGGCGAGGGTGGGGGGGGCGGG
GGAGGCCGGGGCTTGCCCCGTGCAGCCACGATGCTCCTGGACGCCGGACCCCAGTATCCAGCGA
TCGGTGTGACCACCTTTGGTGCATCCCGGCACCACTCGGCGGGCGACGTGGCCGAAAGAGACGT
GGGCCTGGGTATCAACCCGTTCGCCGACGGCATGGGCGCCTTCAAGCTCAACCCCAGTTCGCAC
GAACTGGCCTCGGCCGGCCAGACAGCCTTCACGTCGCAGGCTCCGGGCTACGCCGCTGCCGCGG
CCCTGGGCCACCATCACCACCCCGGCCACGTCGGCTCCTACTCCAGCGCTGCTTTCAATTCTAC
CCGGGACTTTCTGTTCCGCAACCGGGGCTTCGGCGACGCGGCGGCGGCAGCTAGCGCCCAGCAC
AGTCTCTTCGCTGCTTCGGCCGGCGGCTTCGGGGGCCCACACGGCCATACGGACGCCGCGGGCC
ACCTTCTTTTTTCTGGGCTTCACGAGCAGGCGGCCGGCCACGCTTCGCCCAACGTGGTCAACGG
GCAGATGCGGCTAGGTTTCTCCGGGGACATGTACCCACGGCCGGAGCAGTACGGCCAGGTGACC
AGCCCGCGATCCGAGCACTATGCCGCACCGCAGCTTCACGGCTATGGGCCCATGAACGTGAACA
TGGCTGCACACCACGGCGCTGGAGCCTTCTTCCGCTATATGCGCCAACCCATCAAGCAAGAGCT
TATCTGTAAATGGATCGAGCCGGAGCAGCTGGCCAACCCCAAAAAGTCCTGCAACAAAACTTTC
AGCACCATGCACGAGCTGGTCACGCACGTCACGGTGGAGCACGTCGGCGGCCCAGAGCAGAGCA
ACCACATCTGCTTCTGGGAGGAGTGTCCACGCGAGGGCAAGCCCTTCAAAGCCAAATACAAACT
GGTCAACCACATCCGCGTGCATACGGGCGAAAAGCCTTTTCCCTGCCCGTTTCCTGGCTGCGGC
AAGGTTTTCGCGCGTTCAGAGAACCTCAAGATCCACAAAAGGACGCACACAGGGGAGAAGCCCT
TCAAGTGCGAGTTCGAGGGCTGCGACCGGCGCTTCGCCAACAGCAGCGACCGCAAGAAGCACAT
GCACGTGCACACTAGCGACAAGCCCTACCTTTGCAAGATGTGCGATAAGTCCTACACGCACCCC
AGCTCTCTGCGCAAACACATGAAGGTCCATGAGTCCTCTTCTCAGGGCTCACAGCCTTCGCCCG
CCGCCAGCTCGGGGTATGAATCGTCCACGCCACCCACCATCGTGTCTCCCACCACAGACAACCC
GACCACCAGCTCCATGTCGCCCTCTTCCTCCGCGGTCCACCACACAGCCGGCCACAGCGCGCTC
TCTTCCAATTTTAACGAATGGTACGTTTAAAATCAGAAACAAAACATGCCGACCCCCTATTTAA
GAGACTGAACACACACGTATATACATACACAGTATTATTCAAAGAATCCTGAAACTCGAGACAC
CCCTCGTCCCGATCCCGCAAACGTTTGTTTTGTTTGTTTGATTTTGTTTTTAAATCTGCCAGAA
ATCCAGGACTGAGTAAAACAGAGGATGCAACAAACCTTTAGTTCCCCCCTCCCCAAATTTCTTT
TCTTTTTCCCCTCTTTGAAAAGGTTTGGTAGCTGAAGGGCGGGAGGGGTGGACGAGAAGGCGGC
TGCCTGACCGAACACCGCCAAAGGCCCTGATGGCCAATTTCTCTTGGATCAGAACACGCTCTCT
GGGGCTTCAGCTTTTCTTTATCTTCTTGTTTTGTTTTCTTGTAAATACAGAATTATTAGCTTAA
ATCTGTTCTGTTGGATTCTGTATATAGCTACACTTCGGTTGGAGTGGGTGGGTGGGATCGTGGC
GTGGTGGTCTTTGCCTTGGGGAGGGGAGGGCCAGCGGGAGGGGGGAGGGGGAGGGGATGGGCGG
CCGAAAGCCAACTGTTTGTACTGAATGGCGAGAATGTTCTAGTAAATGTGTACCAAAATGTGAA
CTACTTTGTACGATTACAGTCTCCACGTCGACCTAACAGAATATTATTGATATTAATGTGCTTT
TTTTTTGTATAAAGTGCAAACATTTCGTCCCAAAGTCTGAGTACTTTAGTGCAGTGAAATGTTG
TTTCATGTCCTGTCAAGAATTCGTATAGTACGAGCCTGGATCTACGTGTCAAACTGTTCCATTT
GTTTATGTAAAGTGATATTAAAAAGATATAAACTATAGCTGTCCATTGCTTTTGGCAAAATATA
CAACCACACAATGTATATAATTCCTAGTTTCCATATTTATCCGCATGTAAAGGGTCTGGTTTAT
CCATGTTACAGCTATTCAATATTTATGGCTAGAAAAAAAAAACTCGTATGTACACTTTAGTTTC
CAGAACTGTTTGGTAACCTTTCGTACGTTATTAAAGATTCTTAAATCTCA

hide sequence

RefSeq Acc Id:

XM_039082089 ⟹ XP_038938017

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	100,785,282 - 100,797,716 (-)	NCBI
mRatBN7.2	8	91,908,548 - 91,918,020 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_073168	(Get FASTA)	NCBI Sequence Viewer
	XP_008764676	(Get FASTA)	NCBI Sequence Viewer
	XP_038938017	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAF34656	(Get FASTA)	NCBI Sequence Viewer
	EDL77550	(Get FASTA)	NCBI Sequence Viewer
	EDL77551	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000019860
	ENSRNOP00000019860.3

RefSeq Acc Id:

NP_073168 ⟸ NM_022677

- UniProtKB:

Q9JKY2 (UniProtKB/TrEMBL), A6I226 (UniProtKB/TrEMBL), F7FKS2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLLDAGPQYPAIGVTTFGASRHHSAGDVAERDVGLGINPFADGMGAFKLNPSSHELASAGQTAF
TSQAPGYAAAAALGHHHHPGHVGSYSSAAFNSTRDFLFRNRGFGDAAAAASAQHSLFAASAGGF
GGPHGHTDAAGHLLFSGLHEQAAGHASPNVVNGQMRLGFSGDMYPRPEQYGQVTSPRSEHYAAP
QLHGYGPMNVNMAAHHGAGAFFRYMRQPIKQELICKWIEPEQLANPKKSCNKTFSTMHELVTHV
TVEHVGGPEQSNHICFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLK
IHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVH
ESSSQGSQPSPAASSGYESSTPPTIVSPTTDNPTTSSMSPSSSAVHHTAGHSALSSNFNEWYV

hide sequence

RefSeq Acc Id:	XP_008764676 ⟸ XM_008766454
- Peptide Label:	isoform X1
- UniProtKB:	Q9JKY2 (UniProtKB/TrEMBL), A6I226 (UniProtKB/TrEMBL), F7FKS2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLLDAGPQYPAIGVTTFGASRHHSAGDVAERDVGLGINPFADGMGAFKLNPSSHELASAGQTAF TSQAPGYAAAAALGHHHHPGHVGSYSSAAFNSTRDFLFRNRGFGDAAAAASAQHSLFAASAGGF GGPHGHTDAAGHLLFSGLHEQAAGHASPNVVNGQMRLGFSGDMYPRPEQYGQVTSPRSEHYAAP QLHGYGPMNVNMAAHHGAGAFFRYMRQPIKQELICKWIEPEQLANPKKSCNKTFSTMHELVTHV TVEHVGGPEQSNHICFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLK IHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVH ESSSQGSQPSPAASSGYESSTPPTIVSPTTDNPTTSSMSPSSSAVHHTAGHSALSSNFNEWYV hide sequence

Ensembl Acc Id:

ENSRNOP00000019860 ⟸ ENSRNOT00000019860

RefSeq Acc Id:	XP_038938017 ⟸ XM_039082089
- Peptide Label:	isoform X1
- UniProtKB:	Q9JKY2 (UniProtKB/TrEMBL), A6I226 (UniProtKB/TrEMBL), F7FKS2 (UniProtKB/TrEMBL)

Protein Domains

C2H2-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9JKY2-F1-model_v2	AlphaFold	Q9JKY2	1-447	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620110	AgrOrtholog
BioCyc Gene	G2FUF-29563	BioCyc
Ensembl Genes	ENSRNOG00000014644	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000019860	ENTREZGENE
	ENSRNOT00000019860.7	UniProtKB/TrEMBL
Gene3D-CATH	Classic Zinc Finger	UniProtKB/TrEMBL
InterPro	GLI-like	UniProtKB/TrEMBL
	Znf-C2H2_ZIC1-5/GLI1-3-like	UniProtKB/TrEMBL
	Znf_C2H2/integrase_DNA-bd	UniProtKB/TrEMBL
	Znf_C2H2_sf	UniProtKB/TrEMBL
	Znf_ZIC	UniProtKB/TrEMBL
KEGG Report	rno:64618	UniProtKB/TrEMBL
NCBI Gene	64618	ENTREZGENE
PANTHER	GLIS FAMILY ZINC FINGER 2	UniProtKB/TrEMBL
	TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS	UniProtKB/TrEMBL
Pfam	zf-C2H2	UniProtKB/TrEMBL
	zf-C2H2_15	UniProtKB/TrEMBL
	zf_ZIC	UniProtKB/TrEMBL
PhenoGen	Zic1	PhenoGen
PROSITE	ZINC_FINGER_C2H2_1	UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000014644	RatGTEx
SMART	ZnF_C2H2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF57667	UniProtKB/TrEMBL
UniProt	A6I226	ENTREZGENE, UniProtKB/TrEMBL
	A6I227_RAT	UniProtKB/TrEMBL
	F7FKS2	ENTREZGENE, UniProtKB/TrEMBL
	Q9JKY2	ENTREZGENE
UniProt Secondary	Q9JKY2	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2025-11-13	Zic1	Zic family zinc finger 1	Zic1	Zic family member 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-08-01	Zic1	Zic family member 1	Zic1	Zic family member 1 (odd-paired homolog, Drosophila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-25	Zic1	Zic family member 1 (odd-paired homolog, Drosophila)	Zic1	zinc finger protein of the cerebellum 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-11-17	Zic1	zinc finger protein of the cerebellum 1		Zic family member 1 (odd-paired homolog, Drosophila)	Name updated	1299863	APPROVED
2004-09-10	Zic1	Zic family member 1 (odd-paired homolog, Drosophila)		zic protein member 1	Name updated	1299863	APPROVED
2002-08-07	Zic1	zic protein member 1			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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