Rxrg (retinoid X receptor gamma) - Rat Genome Database

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Gene: Rxrg (retinoid X receptor gamma) Rattus norvegicus
Analyze
Symbol: Rxrg
Name: retinoid X receptor gamma
RGD ID: 620046
Description: Predicted to enable molecular condensate scaffold activity; nuclear receptor activity; and retinoic acid-responsive element binding activity. Involved in several processes, including nervous system development; regulation of myelination; and response to retinoic acid. Predicted to be located in cytoplasm and nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human RXRG (retinoid X receptor gamma); PARTICIPATES IN retinoic acid signaling pathway; eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; non-small cell lung carcinoma pathway; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC102553986; MGC109416; nuclear receptor subfamily 2 group B member 3; retinoic acid receptor RXR-gamma; retinoic acid receptor RXR-gamma-like; retinoic X receptor gamma-1; RXR gamma-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81382,276,330 - 82,318,097 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1382,276,291 - 82,318,095 (+)EnsemblGRCr8
mRatBN7.21379,743,430 - 79,785,173 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1379,743,563 - 79,785,167 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1382,373,401 - 82,414,881 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01383,680,439 - 83,722,040 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01380,918,510 - 80,960,010 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01385,818,473 - 85,868,555 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1385,818,427 - 85,868,552 (+)Ensemblrn6Rnor6.0
Rnor_5.01390,460,380 - 90,511,048 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41383,256,823 - 83,298,724 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1379,448,171 - 79,489,515 (+)NCBICelera
RGSC_v3.11383,287,103 - 83,307,114 (+)NCBI
Cytogenetic Map13q24NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dinitrotoluene  (EXP)
2-hydroxyphytanic acid  (ISO)
3,3',5-triiodo-L-thyronine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-phenoxybenzoic acid  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
9-cis-retinoic acid  (ISO)
acrylamide  (EXP)
aldrin  (ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (EXP,ISO)
amiodarone  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
benzo[a]pyrene  (EXP,ISO)
beta-naphthoflavone  (EXP)
bexarotene  (ISO)
bezafibrate  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cadmium sulfate  (ISO)
carbon nanotube  (ISO)
cefaloridine  (EXP)
CGP 52608  (ISO)
chlorpromazine  (ISO)
clofibrate  (EXP)
clozapine  (EXP)
Cuprizon  (EXP)
D-gluconic acid  (EXP)
deoxycholic acid  (EXP)
dexamethasone  (ISO)
Di-n-hexyl phthalate  (ISO)
dibutyl phthalate  (EXP,ISO)
diethyl phthalate  (ISO)
diethylstilbestrol  (EXP)
diheptyl phthalate  (ISO)
diisobutyl phthalate  (EXP)
diisononyl phthalate  (ISO)
Dimethyl phthalate  (ISO)
dimethyl sulfoxide  (ISO)
dioxygen  (EXP)
dipentyl phthalate  (ISO)
dipropyl phthalate  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
fentin hydroxide  (ISO)
fenvalerate  (ISO)
fulvestrant  (ISO)
gamma-hexachlorocyclohexane  (EXP)
genistein  (EXP)
glafenine  (EXP)
griseofulvin  (ISO)
haloperidol  (EXP,ISO)
hydralazine  (ISO)
indometacin  (EXP)
ketamine  (EXP)
ketoconazole  (EXP)
lead diacetate  (EXP)
lipopolysaccharide  (ISO)
mercury dichloride  (EXP)
methapyrilene  (EXP)
methotrexate  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
Muraglitazar  (EXP)
N-methyl-N-nitrosourea  (EXP)
N-nitrosodiethylamine  (EXP)
nimesulide  (EXP)
paracetamol  (ISO)
paraquat  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
phthalic acid  (ISO)
pirinixic acid  (EXP,ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
quercetin  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
Tesaglitazar  (EXP)
testosterone  (EXP)
tetrachloromethane  (EXP)
tetracycline  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
tributylstannane  (EXP,ISO)
trichloroethene  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
triticonazole  (EXP)
valproic acid  (ISO)
vinyl carbamate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Expression of peroxisome proliferator-activated receptors (PPARs) and retinoic acid receptors (RXRs) in rat cortical neurons. Cimini A, etal., Neuroscience. 2005;130(2):325-37.
2. WNT10A/ß-catenin pathway in tumorigenesis of papillary thyroid carcinoma. Dong T, etal., Oncol Rep. 2017 Aug;38(2):1287-1294. doi: 10.3892/or.2017.5777. Epub 2017 Jul 3.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Regulation of retinoid X receptor-gamma gene transcript levels in rat heart cells. Georgiades P and Brickell PM, Cell Biol Int. 1998;22(6):457-63.
5. Differential expression of the rat retinoid X receptor gamma gene during skeletal muscle differentiation suggests a role in myogenesis. Georgiades P and Brickell PM, Dev Dyn 1997 Nov;210(3):227-35.
6. Retinoid X receptor-gamma gene expression is developmentally regulated in the embryonic rodent peripheral nervous system. Georgiades P, etal., Anat Embryol (Berl). 1998 Jun;197(6):477-84.
7. International Union of Pharmacology. LXIII. Retinoid X receptors. Germain P, etal., Pharmacol Rev. 2006 Dec;58(4):760-72.
8. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
9. Antiestrogenic activity of vitamin A in in vivo uterotrophic assay. Koda T, etal., Life Sci. 2007 Feb 13;80(10):945-9. Epub 2006 Nov 22.
10. Retinoic acid regulates myelin formation in the peripheral nervous system. Latasa MJ, etal., Glia. 2010 Sep;58(12):1451-64.
11. Epigenetic inactivation of retinoid X receptor genes in non-small cell lung cancer and the relationship with clinicopathologic features. Lee SM, etal., Cancer Genet Cytogenet. 2010 Feb;197(1):39-45. doi: 10.1016/j.cancergencyto.2009.10.008.
12. Vitamin A regulation of gene expression: molecular mechanism of a prototype gene. McGrane MM J Nutr Biochem. 2007 Aug;18(8):497-508. Epub 2007 Feb 22.
13. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
14. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
15. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
16. GOA pipeline RGD automated data pipeline
17. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
18. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
19. Time-response effects of testicular gene expression profiles in Sprague-Dawley male rats treated with di(n-butyl) phthalate. Ryu JY, etal., J Toxicol Environ Health A. 2008;71(23):1542-9.
Additional References at PubMed
PMID:1312497   PMID:7823919   PMID:7831303   PMID:8391126   PMID:12477932   PMID:15878969   PMID:17195188   PMID:17963722   PMID:23017197   PMID:30015907  


Genomics

Comparative Map Data
Rxrg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81382,276,330 - 82,318,097 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1382,276,291 - 82,318,095 (+)EnsemblGRCr8
mRatBN7.21379,743,430 - 79,785,173 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1379,743,563 - 79,785,167 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1382,373,401 - 82,414,881 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01383,680,439 - 83,722,040 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01380,918,510 - 80,960,010 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01385,818,473 - 85,868,555 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1385,818,427 - 85,868,552 (+)Ensemblrn6Rnor6.0
Rnor_5.01390,460,380 - 90,511,048 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41383,256,823 - 83,298,724 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1379,448,171 - 79,489,515 (+)NCBICelera
RGSC_v3.11383,287,103 - 83,307,114 (+)NCBI
Cytogenetic Map13q24NCBI
RXRG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381165,400,922 - 165,445,126 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1165,400,922 - 165,445,355 (-)Ensemblhg38GRCh38
GRCh371165,370,159 - 165,414,363 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361163,636,974 - 163,681,054 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341162,102,008 - 162,146,088NCBI
Celera1138,475,332 - 138,519,756 (-)NCBICelera
Cytogenetic Map1q23.3NCBI
HuRef1136,616,922 - 136,661,341 (-)NCBIHuRef
CHM1_11166,792,871 - 166,837,301 (-)NCBICHM1_1
T2T-CHM13v2.01164,747,271 - 164,791,474 (-)NCBIT2T-CHM13v2.0
Rxrg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391167,425,902 - 167,467,191 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1167,425,953 - 167,467,192 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381167,598,362 - 167,639,623 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1167,598,384 - 167,639,623 (+)Ensemblmm10GRCm38
MGSCv371169,528,493 - 169,569,754 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361169,435,059 - 169,476,298 (+)NCBIMGSCv36mm8
Celera1170,022,008 - 170,069,461 (+)NCBICelera
Cytogenetic Map1H2.3NCBI
cM Map174.99NCBI
Rxrg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546211,238,794 - 11,281,956 (+)Ensembl
ChiLan1.0NW_00495546211,238,963 - 11,281,905 (+)NCBIChiLan1.0ChiLan1.0
RXRG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2184,320,687 - 84,365,083 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1183,989,216 - 84,033,594 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01140,832,717 - 140,877,046 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11144,623,133 - 144,667,503 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1144,623,133 - 144,723,494 (-)EnsemblpanPan2panpan1.1
RXRG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13817,867,123 - 17,912,328 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3817,867,182 - 17,920,085 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3817,922,970 - 17,968,200 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03817,947,065 - 17,992,337 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3817,947,141 - 18,000,604 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13817,919,625 - 17,964,835 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03818,271,342 - 18,316,575 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03818,565,728 - 18,610,954 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rxrg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344101,933,905 - 101,979,926 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648119,789,641 - 19,826,698 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648119,789,753 - 19,826,665 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RXRG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl485,308,508 - 85,357,137 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1485,158,313 - 85,357,116 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2492,982,235 - 93,063,524 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RXRG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12563,444,128 - 63,490,594 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2563,443,944 - 63,490,635 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605565,204,356 - 65,250,988 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rxrg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248263,736,290 - 3,780,338 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248263,723,056 - 3,969,597 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Rxrg
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11046,905,306 - 46,946,978 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rxrg
252 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:100
Count of miRNA genes:68
Interacting mature miRNAs:80
Transcripts:ENSRNOT00000006117
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134863963493639634Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133721624190057603Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
8655951Rf63Renal function QTL 6312.2blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)1371610804109350286Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)137161080489333251Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134874981487285480Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133996821183286298Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)137161080489333251Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137298450699745408Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)137161080489333251Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1367635937109350286Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134098358585983585Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)134735425894285672Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)1365613454109350286Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1368983334109350286Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)136242459288113509Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1367635937109350286Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
1576318Schws5Schwannoma susceptibility QTL 50.0351nervous system integrity trait (VT:0010566)post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)1364497900109350286Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133981472684814726Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133996821184968211Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1364375743109350286Rat
11530006Niddm72Non-insulin dependent diabetes mellitus QTL 720.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)133828629883286298Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1367635937109350286Rat

Markers in Region
RH129058  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21379,785,001 - 79,785,172 (+)MAPPERmRatBN7.2
Rnor_6.01385,868,378 - 85,868,548NCBIRnor6.0
Rnor_5.01390,510,875 - 90,511,045UniSTSRnor5.0
RGSC_v3.41383,298,558 - 83,298,728UniSTSRGSC3.4
Celera1379,489,349 - 79,489,519UniSTS
RH 3.4 Map13525.1UniSTS
Cytogenetic Map13q24UniSTS
RH135186  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21379,779,475 - 79,779,660 (+)MAPPERmRatBN7.2
Rnor_6.01385,862,852 - 85,863,036NCBIRnor6.0
Rnor_5.01390,505,349 - 90,505,533UniSTSRnor5.0
RGSC_v3.41383,293,032 - 83,293,216UniSTSRGSC3.4
Celera1379,483,823 - 79,484,007UniSTS
RH 3.4 Map13525.7UniSTS
Cytogenetic Map13q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 12 67 148 91 90 59 74 59 6 331 174 11 127 81 88 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000006117   ⟹   ENSRNOP00000006117
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1382,276,291 - 82,318,095 (+)Ensembl
mRatBN7.2 Ensembl1379,743,563 - 79,785,167 (+)Ensembl
Rnor_6.0 Ensembl1385,818,473 - 85,868,543 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000077227   ⟹   ENSRNOP00000070882
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1382,291,235 - 82,318,095 (+)Ensembl
mRatBN7.2 Ensembl1379,758,315 - 79,785,167 (+)Ensembl
Rnor_6.0 Ensembl1385,818,427 - 85,868,552 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000121542   ⟹   ENSRNOP00000105016
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1382,276,808 - 82,318,095 (+)Ensembl
RefSeq Acc Id: NM_031765   ⟹   NP_113953
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81382,276,487 - 82,318,092 (+)NCBI
mRatBN7.21379,743,563 - 79,785,168 (+)NCBI
Rnor_6.01385,818,473 - 85,868,544 (+)NCBI
Rnor_5.01390,460,380 - 90,511,048 (+)NCBI
RGSC_v3.41383,256,823 - 83,298,724 (+)RGD
Celera1379,448,171 - 79,489,515 (+)RGD
Sequence:
RefSeq Acc Id: XM_039091122   ⟹   XP_038947050
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81382,276,330 - 82,318,097 (+)NCBI
mRatBN7.21379,743,430 - 79,785,173 (+)NCBI
RefSeq Acc Id: XM_039091123   ⟹   XP_038947051
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81382,296,370 - 82,318,097 (+)NCBI
mRatBN7.21379,763,444 - 79,785,173 (+)NCBI
RefSeq Acc Id: NP_113953   ⟸   NM_031765
- UniProtKB: Q5BJR8 (UniProtKB/Swiss-Prot),   A6IDL7 (UniProtKB/TrEMBL),   A0A0G2JZ22 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000006117   ⟸   ENSRNOT00000006117
Ensembl Acc Id: ENSRNOP00000070882   ⟸   ENSRNOT00000077227
RefSeq Acc Id: XP_038947050   ⟸   XM_039091122
- Peptide Label: isoform X1
- UniProtKB: A0A8L2Q373 (UniProtKB/TrEMBL),   A0A0G2JZ22 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038947051   ⟸   XM_039091123
- Peptide Label: isoform X2
- UniProtKB: Q64116 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000105016   ⟸   ENSRNOT00000121542
Protein Domains
NR LBD   Nuclear receptor

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5BJR8-F1-model_v2 AlphaFold Q5BJR8 1-463 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698991
Promoter ID:EPDNEW_R9501
Type:multiple initiation site
Name:Rxrg_1
Description:retinoid X receptor gamma
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01385,818,358 - 85,818,418EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620046 AgrOrtholog
BioCyc Gene G2FUF-17505 BioCyc
Ensembl Genes ENSRNOG00000004537 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000006117 ENTREZGENE
  ENSRNOT00000121542 ENTREZGENE
Gene3D-CATH 1.10.565.10 UniProtKB/Swiss-Prot
  3.30.50.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7319081 IMAGE-MGC_LOAD
InterPro NHR-like_dom_sf UniProtKB/Swiss-Prot
  Nuc_recep-AF1 UniProtKB/Swiss-Prot
  Nucl_hrmn_rcpt_lig-bd UniProtKB/Swiss-Prot
  Nuclear_hormone_rcpt_NR2 UniProtKB/Swiss-Prot
  Nuclear_hrmn_rcpt UniProtKB/Swiss-Prot
  Retinoid-X_rcpt/HNF4 UniProtKB/Swiss-Prot
  Znf_hrmn_rcpt UniProtKB/Swiss-Prot
  Znf_NHR/GATA UniProtKB/Swiss-Prot
KEGG Report rno:83574 UniProtKB/Swiss-Prot
MGC_CLONE MGC:109416 IMAGE-MGC_LOAD
NCBI Gene 83574 ENTREZGENE
PANTHER NUCLEAR HORMONE RECEPTOR UniProtKB/Swiss-Prot
Pfam Hormone_recep UniProtKB/Swiss-Prot
  Nuc_recep-AF1 UniProtKB/Swiss-Prot
  zf-C4 UniProtKB/Swiss-Prot
PhenoGen Rxrg PhenoGen
PRINTS RETINOIDXR UniProtKB/Swiss-Prot
  STRDHORMONER UniProtKB/Swiss-Prot
  STROIDFINGER UniProtKB/Swiss-Prot
PROSITE NR_LBD UniProtKB/Swiss-Prot
  NUCLEAR_REC_DBD_1 UniProtKB/Swiss-Prot
  NUCLEAR_REC_DBD_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000004537 RatGTEx
SMART HOLI UniProtKB/Swiss-Prot
  ZnF_C4 UniProtKB/Swiss-Prot
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/Swiss-Prot
  SSF48508 UniProtKB/Swiss-Prot
UniProt A0A0G2JZ22 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2Q373 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LTK4_RAT UniProtKB/TrEMBL
  A6IDL7 ENTREZGENE, UniProtKB/TrEMBL
  A6IDL8_RAT UniProtKB/TrEMBL
  Q5BJR8 ENTREZGENE
  Q64116 ENTREZGENE, UniProtKB/TrEMBL
  RXRG_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Rxrg  retinoid X receptor gamma  LOC102553986  retinoic acid receptor RXR-gamma-like  Data merged from RGD:7606576 737654 PROVISIONAL
2013-12-18 LOC102553986  retinoic acid receptor RXR-gamma-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-20 Rxrg  retinoid X receptor gamma      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Rxrg  retinoid X receptor gamma      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in differentiating myoblasts, but not in proliferating myoblasts 633976