Mafg (MAF bZIP transcription factor G) - Rat Genome Database

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Gene: Mafg (MAF bZIP transcription factor G) Rattus norvegicus
Analyze
Symbol: Mafg
Name: MAF bZIP transcription factor G
RGD ID: 619953
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Involved in regulation of cellular pH. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Orthologous to human MAFG (MAF bZIP transcription factor G); PARTICIPATES IN nuclear factor, erythroid 2 like 2 signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: transcription factor MafG; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G; v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein G; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian); v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810106,401,633 - 106,410,159 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.210105,903,307 - 105,911,808 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10105,903,237 - 105,912,026 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx10111,007,074 - 111,015,576 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010110,470,111 - 110,478,613 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010105,823,759 - 105,832,258 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.010109,802,877 - 109,811,476 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10109,806,159 - 109,811,323 (-)Ensemblrn6Rnor6.0
Rnor_5.010109,395,929 - 109,404,465 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.410110,019,741 - 110,024,927 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera10104,449,965 - 104,455,151 (-)NCBICelera
RGSC_v3.110110,034,252 - 110,039,431 (-)NCBI
Cytogenetic Map10q32.3NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(E)-cinnamyl alcohol  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
2-tert-butylhydroquinone  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
4-hydroxynon-2-enal  (ISO)
acrolein  (EXP,ISO)
acrylamide  (ISO)
all-trans-retinoic acid  (ISO)
alpha-hexylcinnamaldehyde  (ISO)
alpha-pinene  (ISO)
amiodarone  (ISO)
ammonium chloride  (EXP)
andrographolide  (ISO)
aristolochic acid A  (ISO)
arotinoid acid  (ISO)
azoxystrobin  (ISO)
Bandrowski's base  (ISO)
Bardoxolone methyl  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzoic acid  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
brequinar  (ISO)
butan-1-ol  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
cadmium sulfate  (ISO)
cannabidiol  (ISO)
CGP 52608  (ISO)
chenodeoxycholic acid  (ISO)
CHIR 99021  (ISO)
chloroacetaldehyde  (ISO)
chloroprene  (ISO)
chlorpyrifos  (ISO)
cinnamyl alcohol  (ISO)
cisplatin  (ISO)
clodronic acid  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
cortisol  (ISO)
CU-O LINKAGE  (ISO)
cyclosporin A  (EXP,ISO)
DDE  (ISO)
deoxycholic acid  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
diethyl malate  (ISO)
diethyl maleate  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
eugenol  (ISO)
fenofibrate  (EXP,ISO)
fenthion  (ISO)
flutamide  (EXP)
folic acid  (ISO)
gentamycin  (EXP)
geraniol  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
GSK-J4  (ISO)
hexane  (ISO)
hydrogen peroxide  (ISO)
hypochlorous acid  (ISO)
ibuprofen  (EXP)
ifosfamide  (ISO)
iron dichloride  (ISO)
isoeugenol  (ISO)
L-ascorbic acid  (ISO)
L-ascorbic acid 2-phosphate  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
lithocholic acid  (ISO)
menadione  (ISO)
mercury dibromide  (ISO)
metformin  (EXP)
methidathion  (ISO)
methyl methanesulfonate  (ISO)
methyl salicylate  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
nefazodone  (ISO)
nickel sulfate  (ISO)
ochratoxin A  (ISO)
organoselenium compound  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP)
paraquat  (ISO)
pentachlorophenol  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
phlorizin  (ISO)
phorone  (EXP)
picoxystrobin  (ISO)
potassium chromate  (ISO)
propan-2-ol  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
reactive oxygen species  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
S-adenosyl-L-methioninate  (ISO)
S-adenosyl-L-methionine  (ISO)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
trans-isoeugenol  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (EXP)
triclosan  (ISO)
troglitazone  (EXP)
tunicamycin  (ISO)
urethane  (ISO)
ursodeoxycholic acid  (ISO)
valproic acid  (ISO)
XAV939  (ISO)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. The Nrf2 regulatory network provides an interface between redox and intermediary metabolism. Hayes JD and Dinkova-Kostova AT, Trends Biochem Sci. 2014 Apr;39(4):199-218. doi: 10.1016/j.tibs.2014.02.002. Epub 2014 Mar 16.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. MafG-2 is a novel Maf protein that is expressed by stimulation of extracellular H(+). Shimokawa N, etal., Cell Signal 2001 Nov;13(11):835-9.
8. Cloning of MafG homologue from the rat brain by differential display and its expression after hypercapnic stimulation. Shimokawa N, etal., Mol Cell Biochem 2000 Jan;203(1-2):135-41.
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:9679061   PMID:12220541   PMID:14517290   PMID:14978030   PMID:15087497   PMID:15574414   PMID:15828020   PMID:17928287  


Genomics

Comparative Map Data
Mafg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810106,401,633 - 106,410,159 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.210105,903,307 - 105,911,808 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10105,903,237 - 105,912,026 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx10111,007,074 - 111,015,576 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010110,470,111 - 110,478,613 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010105,823,759 - 105,832,258 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.010109,802,877 - 109,811,476 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10109,806,159 - 109,811,323 (-)Ensemblrn6Rnor6.0
Rnor_5.010109,395,929 - 109,404,465 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.410110,019,741 - 110,024,927 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera10104,449,965 - 104,455,151 (-)NCBICelera
RGSC_v3.110110,034,252 - 110,039,431 (-)NCBI
Cytogenetic Map10q32.3NCBI
MAFG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381781,918,270 - 81,931,244 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1781,918,270 - 81,927,735 (-)Ensemblhg38GRCh38
GRCh371779,876,146 - 79,885,611 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361777,469,438 - 77,478,879 (-)NCBIBuild 36Build 36hg18NCBI36
Celera1776,480,214 - 76,489,629 (-)NCBICelera
Cytogenetic Map17q25.3NCBI
HuRef1775,277,766 - 75,297,553 (-)NCBIHuRef
CHM1_11779,962,349 - 79,971,791 (-)NCBICHM1_1
T2T-CHM13v2.01782,785,430 - 82,798,403 (-)NCBIT2T-CHM13v2.0
Mafg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911120,515,943 - 120,525,771 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11120,515,943 - 120,524,426 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3811120,625,117 - 120,634,955 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11120,625,117 - 120,633,600 (-)Ensemblmm10GRCm38
MGSCv3711120,489,662 - 120,494,861 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3611120,444,438 - 120,449,637 (-)NCBIMGSCv36mm8
Celera11132,363,642 - 132,365,175 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1184.35NCBI
Mafg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555061,247,293 - 1,252,167 (+)Ensembl
ChiLan1.0NW_0049555061,247,294 - 1,252,167 (+)NCBIChiLan1.0ChiLan1.0
MAFG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21998,454,393 - 98,463,741 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan117103,355,168 - 103,364,469 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01776,323,874 - 76,333,300 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11782,026,365 - 82,035,036 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1782,030,699 - 82,031,278 (-)EnsemblpanPan2panpan1.1
MAFG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.19368,102 - 373,825 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl9372,216 - 372,797 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha9970,324 - 975,925 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.09961,543 - 967,144 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl9965,535 - 966,116 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.19986,697 - 992,297 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.091,113,317 - 1,118,910 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.091,191,956 - 1,200,828 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mafg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602978,486 - 986,842 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365945,424,940 - 5,430,097 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365945,425,117 - 5,430,057 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAFG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl121,071,632 - 1,074,688 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1121,069,074 - 1,078,081 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MAFG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11673,793,362 - 73,801,185 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1673,796,453 - 73,797,034 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607745,244,171 - 45,253,347 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mafg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480110,764,186 - 10,769,454 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462480110,760,599 - 10,769,578 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Mafg
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1963,390,223 - 63,397,791 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mafg
35 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:591
Count of miRNA genes:288
Interacting mature miRNAs:364
Transcripts:ENSRNOT00000054970
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7387312Bw125Body weight QTL 12530.0047retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight (CMO:0000356)1065390777107713808Rat
1354641Bvd2Brain ventricular dilatation QTL 26.360.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)1093723381107556066Rat
8657410Bp374Blood pressure QTL 374heart left ventricle size trait (VT:0002753)heart left ventricle end-diastolic diameter (CMO:0000982)1067476608107713808Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063719161107713808Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1052269185107713808Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042546145107713808Rat
12903252Cm113Cardiac mass QTL 1130.047heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)1066817119107713808Rat
61396Bp9Blood pressure QTL 94.80.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068920187107713808Rat
2298548Neuinf7Neuroinflammation QTL 73.4nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1064939013107713808Rat
1302404Cia27Collagen induced arthritis QTL 272.60.0045joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)1076951790107713808Rat
1358915Stresp7Stress response QTL 73.52blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)1065307813107713808Rat
70168Eae12Experimental allergic encephalomyelitis QTL 120.0009nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)1073599825107713808Rat
634320Niddm49Non-insulin dependent diabetes mellitus QTL 494.41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1089039175107713808Rat
70363Bp71Blood pressure QTL 710.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1061843496106843496Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1054296227107713808Rat
6893366Bw106Body weight QTL 1060.30.47body mass (VT:0001259)body weight (CMO:0000012)1070698731107713808Rat
1576313Pia25Pristane induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1096620293107713808Rat
12903269Am15Aortic mass QTL 150.042aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1066817119107713808Rat
12903266Cm114Cardiac mass QTL 1140.02heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)1066817119107713808Rat
1578672Bmd16Bone mineral density QTL 166.2femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)1097202388107556066Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
1576307Cia28Collagen induced arthritis QTL 28joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1096620293107713808Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040535708107713808Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1062556066107556066Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
1581559Eae18Experimental allergic encephalomyelitis QTL 180.00002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1066108888107555881Rat
70193Mcs7Mammary carcinoma susceptibility QTL 72.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072724423107713808Rat
12880372Am12Aortic mass QTL 120.003aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1066817119107713808Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1062556066107556066Rat
61363Oia3Oil induced arthritis QTL 30.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1087807758107713808Rat
12880375Kidm66Kidney mass QTL 660.009kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1066817119107713808Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
12880370Cm105Cardiac mass QTL 1050.008heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)1066817119107713808Rat
1600367Mcs15Mammary carcinoma susceptibility QTL 154.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072724423107713808Rat
12880371Cm106Cardiac mass QTL 1060.007heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)1066817119107713808Rat
631537Oia4Oil induced arthritis QTL 4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1076128947107713808Rat
1300137Bp186Blood pressure QTL 1863.57arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1091127270107556066Rat
634354Rends3Renal damage susceptibility QTL 30.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)1061997479106997479Rat
61436Cia5Collagen induced arthritis QTL 54.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1091727883107713808Rat
11565453Kidm58Kidney mass QTL 580.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1066817119107713808Rat
2301405Cm69Cardiac mass QTL 690.031heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)1066817119107713808Rat
1578663Bss18Bone structure and strength QTL 183.6femur width (VT:1000666)femoral neck width (CMO:0001695)1097202388107556066Rat

Markers in Region
Mafg  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr810106,406,219 - 106,406,396 (+)Marker Load Pipeline
mRatBN7.210105,907,895 - 105,908,072 (+)MAPPERmRatBN7.2
Rnor_6.010109,807,464 - 109,807,640NCBIRnor6.0
Rnor_5.010109,400,516 - 109,400,692UniSTSRnor5.0
RGSC_v3.410110,021,068 - 110,021,244UniSTSRGSC3.4
Celera10104,451,292 - 104,451,468UniSTS
Cytogenetic Map10q32.3UniSTS
Mafg  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.210105,906,636 - 105,907,531 (+)MAPPERmRatBN7.2
Rnor_6.010109,806,205 - 109,807,099NCBIRnor6.0
Rnor_5.010109,399,257 - 109,400,151UniSTSRnor5.0
Celera10104,450,033 - 104,450,927UniSTS
Cytogenetic Map10q32.3UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_022386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006247912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006247913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006247921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006247922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB026487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB050011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC131537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC078828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000054970   ⟹   ENSRNOP00000051853
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl10105,906,591 - 105,912,026 (-)Ensembl
Rnor_6.0 Ensembl10109,806,159 - 109,811,323 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000104193   ⟹   ENSRNOP00000091294
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl10105,903,237 - 105,911,010 (-)Ensembl
RefSeq Acc Id: NM_022386   ⟹   NP_071781
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,401,633 - 106,410,132 (-)NCBI
mRatBN7.210105,903,307 - 105,911,808 (-)NCBI
Rnor_6.010109,806,137 - 109,811,323 (-)NCBI
Rnor_5.010109,395,929 - 109,404,465 (-)NCBI
RGSC_v3.410110,019,741 - 110,024,927 (-)RGD
Celera10104,449,965 - 104,455,151 (-)RGD
Sequence:
RefSeq Acc Id: XM_006247913   ⟹   XP_006247975
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,401,633 - 106,409,912 (-)NCBI
mRatBN7.210105,903,307 - 105,911,588 (-)NCBI
Rnor_6.010109,802,877 - 109,811,156 (-)NCBI
Rnor_5.010109,395,929 - 109,404,465 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006247921   ⟹   XP_006247983
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,401,633 - 106,409,912 (-)NCBI
mRatBN7.210105,903,307 - 105,911,588 (-)NCBI
Rnor_6.010109,802,877 - 109,811,156 (-)NCBI
Rnor_5.010109,395,929 - 109,404,465 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006247922   ⟹   XP_006247984
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,401,633 - 106,409,912 (-)NCBI
mRatBN7.210105,903,307 - 105,911,588 (-)NCBI
Rnor_6.010109,802,877 - 109,811,156 (-)NCBI
Rnor_5.010109,395,929 - 109,404,465 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008768482   ⟹   XP_008766704
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,401,633 - 106,407,008 (-)NCBI
mRatBN7.210105,903,307 - 105,908,680 (-)NCBI
Rnor_6.010109,802,877 - 109,811,156 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039086787   ⟹   XP_038942715
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,401,633 - 106,409,912 (-)NCBI
mRatBN7.210105,903,307 - 105,911,588 (-)NCBI
RefSeq Acc Id: XM_039086788   ⟹   XP_038942716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,401,633 - 106,409,912 (-)NCBI
mRatBN7.210105,903,307 - 105,911,588 (-)NCBI
RefSeq Acc Id: XM_063269807   ⟹   XP_063125877
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,401,633 - 106,409,912 (-)NCBI
RefSeq Acc Id: XM_063269808   ⟹   XP_063125878
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,401,633 - 106,410,159 (-)NCBI
RefSeq Acc Id: XM_063269809   ⟹   XP_063125879
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,401,633 - 106,409,912 (-)NCBI
RefSeq Acc Id: XM_063269810   ⟹   XP_063125880
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,401,633 - 106,409,912 (-)NCBI
RefSeq Acc Id: XM_063269811   ⟹   XP_063125881
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,401,633 - 106,410,152 (-)NCBI
RefSeq Acc Id: NP_071781   ⟸   NM_022386
- Sequence:
RefSeq Acc Id: XP_006247983   ⟸   XM_006247921
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006247975   ⟸   XM_006247913
- Peptide Label: isoform X1
- UniProtKB: A0A8L2QQP9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006247984   ⟸   XM_006247922
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008766704   ⟸   XM_008768482
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSRNOP00000051853   ⟸   ENSRNOT00000054970
RefSeq Acc Id: XP_038942716   ⟸   XM_039086788
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038942715   ⟸   XM_039086787
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000091294   ⟸   ENSRNOT00000104193
RefSeq Acc Id: XP_063125878   ⟸   XM_063269808
- Peptide Label: isoform X2
- UniProtKB: Q99N83 (UniProtKB/Swiss-Prot),   Q76MX4 (UniProtKB/Swiss-Prot),   A6HLH1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125881   ⟸   XM_063269811
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063125880   ⟸   XM_063269810
- Peptide Label: isoform X2
- UniProtKB: Q99N83 (UniProtKB/Swiss-Prot),   Q76MX4 (UniProtKB/Swiss-Prot),   A6HLH1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125879   ⟸   XM_063269809
- Peptide Label: isoform X2
- UniProtKB: Q99N83 (UniProtKB/Swiss-Prot),   Q76MX4 (UniProtKB/Swiss-Prot),   A6HLH1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125877   ⟸   XM_063269807
- Peptide Label: isoform X2
- UniProtKB: Q99N83 (UniProtKB/Swiss-Prot),   Q76MX4 (UniProtKB/Swiss-Prot),   A6HLH1 (UniProtKB/TrEMBL)
Protein Domains
bZIP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q76MX4-F1-model_v2 AlphaFold Q76MX4 1-189 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697971
Promoter ID:EPDNEW_R8495
Type:multiple initiation site
Name:Mafg_1
Description:MAF bZIP transcription factor G
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.010109,811,376 - 109,811,436EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619953 AgrOrtholog
BioCyc Gene G2FUF-22401 BioCyc
Ensembl Genes ENSRNOG00000036697 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00000072854 ENTREZGENE
Ensembl Transcript ENSRNOT00000104193.1 UniProtKB/Swiss-Prot
  ENSRNOT00000124468 ENTREZGENE
  ENSRNOT00000144958 ENTREZGENE
Gene3D-CATH 1.20.5.170 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7127046 IMAGE-MGC_LOAD
InterPro bZIP UniProtKB/Swiss-Prot
  bZIP_Maf UniProtKB/Swiss-Prot
  bZIP_sf UniProtKB/Swiss-Prot
  TF_DNA-bd_sf UniProtKB/Swiss-Prot
  Transciption_factor_Maf_fam UniProtKB/Swiss-Prot
KEGG Report rno:64188 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93443 IMAGE-MGC_LOAD
NCBI Gene 64188 ENTREZGENE
PANTHER PTHR10129 UniProtKB/Swiss-Prot
  PTHR10129:SF15 UniProtKB/Swiss-Prot
Pfam bZIP_Maf UniProtKB/Swiss-Prot
PhenoGen Mafg PhenoGen
PROSITE BZIP UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000036697 RatGTEx
  ENSRNOG00000072854 RatGTEx
SMART BRLZ UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47454 UniProtKB/Swiss-Prot
  SSF57959 UniProtKB/Swiss-Prot
UniProt A0A8L2QQP9 ENTREZGENE
  A0ABK0LD61_RAT UniProtKB/TrEMBL
  A0ABK0LZI7_RAT UniProtKB/TrEMBL
  A6HLH1 ENTREZGENE, UniProtKB/TrEMBL
  MAFG_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q99N83 ENTREZGENE
UniProt Secondary Q99N83 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-18 Mafg  MAF bZIP transcription factor G  Mafg  v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-07-18 Mafg  v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G  Mafg  v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-30 Mafg  v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)  Mafg  v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Mafg  v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)    v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein G  Name updated 1299863 APPROVED
2002-08-07 Mafg  v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein G      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_transcript splice variant MafG-2 contains an insertion of 27 amino acids 633304