Cd69 (Cd69 molecule) - Rat Genome Database

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Gene: Cd69 (Cd69 molecule) Rattus norvegicus
Analyze
Symbol: Cd69
Name: Cd69 molecule
RGD ID: 61318
Description: Enables calcium ion binding activity. Predicted to be involved in cellular response to xenobiotic stimulus and negative regulation of T cell migration. Predicted to act upstream of or within T cell migration; negative regulation of T-helper 17 cell lineage commitment; and sphingosine-1-phosphate receptor signaling pathway. Predicted to be located in external side of plasma membrane. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane. Orthologous to human CD69 (CD69 molecule); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: C-type lectin domain family 2 member A; CD69 antigen; early activation antigen CD69
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Ciaa4 Cia24
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84164,411,485 - 164,419,403 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4164,411,485 - 164,419,509 (-)EnsemblGRCr8
mRatBN7.24162,725,446 - 162,733,364 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4162,725,446 - 162,733,542 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4168,960,276 - 168,968,194 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04164,743,221 - 164,751,139 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04163,377,272 - 163,385,190 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04163,041,147 - 163,049,065 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4163,041,141 - 163,049,084 (-)Ensemblrn6Rnor6.0
Rnor_5.04211,685,114 - 211,693,033 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44166,527,683 - 166,535,601 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4151,413,397 - 151,421,315 (-)NCBICelera
RGSC_v3.14166,773,564 - 166,775,469 (-)NCBI
Cytogenetic Map4q42NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-anisomycin  (ISO)
(-)-demecolcine  (ISO)
1-(5-isoquinolinesulfonyl)-2-methylpiperazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-tert-butylhydroquinone  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3'-diindolylmethane  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-(2-methylpiperazine-1-sulfonyl)isoquinoline  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acetamide  (EXP)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
beta-D-glucan  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
bucladesine  (ISO)
buta-1,3-diene  (ISO)
Calcimycin  (ISO)
cannabidiol  (ISO)
capsiate  (ISO)
carbon nanotube  (ISO)
chloroprene  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
dacarbazine  (ISO)
decabromodiphenyl ether  (EXP)
delta-tocotrienol  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dieldrin  (ISO)
dimethylarsinic acid  (ISO)
dioxygen  (ISO)
diuron  (ISO)
enniatin  (ISO)
erlotinib hydrochloride  (ISO)
ethyl methanesulfonate  (ISO)
flucloxacillin  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
gamma-hexachlorocyclohexane  (ISO)
graphite  (EXP)
halothane  (ISO)
hydroquinone  (ISO)
indole-3-methanol  (ISO)
ionomycin  (ISO)
isotretinoin  (ISO)
L-ascorbic acid  (ISO)
lipopolysaccharide  (ISO)
malathion  (ISO)
MC1568  (ISO)
methyl methanesulfonate  (ISO)
methylarsonic acid  (ISO)
mifepristone  (ISO)
mocetinostat  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
N-(6-acetamidohexyl)acetamide  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
ochratoxin A  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
Pentoxifylline  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
prostratin  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
tamibarotene  (ISO)
tetraphene  (ISO)
thapsigargin  (ISO)
Theaflavin 3,3'-digallate  (ISO)
titanium dioxide  (ISO)
Tolmetin glucuronide  (ISO)
topotecan  (EXP)
Tributyltin oxide  (ISO)
trichloroacetic acid  (ISO)
trichostatin A  (ISO)
Triptolide  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
vorinostat  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Genetic dissection of a rat model for rheumatoid arthritis: significant gender influences on autosomal modifier loci Furuya T, etal., Hum Mol Genet 2000 Sep 22;9(15):2241-50
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. Lymphocyte activation receptors: new structural paradigms in group V of C-type animal lectins. Pavlicek J, etal., Biochem Soc Trans 2004 Dec;32(Pt 6):1124-6.
6. Molecular characterization of binding of calcium and carbohydrates by an early activation antigen of lymphocytes CD69. Pavlicek J, etal., Biochemistry 2003 Aug 12;42(31):9295-306.
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Functional analysis of ligand-binding and signal transduction domains of CD69 and CD23 C-type lectin leukocyte receptors. Sancho D, etal., J Immunol 2000 Oct 1;165(7):3868-75.
Additional References at PubMed
PMID:7589135   PMID:7630421   PMID:11101293   PMID:12477932   PMID:12697665   PMID:15184345   PMID:15240667   PMID:16227984   PMID:16301745   PMID:16973387   PMID:17082577   PMID:17137799  
PMID:18776904   PMID:18792410   PMID:18836449   PMID:19008373   PMID:19015308   PMID:19109165   PMID:19349303   PMID:19723499   PMID:20544345   PMID:21357543   PMID:21460847  


Genomics

Comparative Map Data
Cd69
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84164,411,485 - 164,419,403 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4164,411,485 - 164,419,509 (-)EnsemblGRCr8
mRatBN7.24162,725,446 - 162,733,364 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4162,725,446 - 162,733,542 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4168,960,276 - 168,968,194 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04164,743,221 - 164,751,139 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04163,377,272 - 163,385,190 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04163,041,147 - 163,049,065 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4163,041,141 - 163,049,084 (-)Ensemblrn6Rnor6.0
Rnor_5.04211,685,114 - 211,693,033 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44166,527,683 - 166,535,601 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4151,413,397 - 151,421,315 (-)NCBICelera
RGSC_v3.14166,773,564 - 166,775,469 (-)NCBI
Cytogenetic Map4q42NCBI
CD69
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38129,752,486 - 9,760,901 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl129,752,486 - 9,760,901 (-)Ensemblhg38GRCh38
GRCh37129,905,082 - 9,913,497 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36129,796,349 - 9,804,764 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34129,796,350 - 9,804,764NCBI
Celera1215,066,458 - 15,074,875 (-)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef129,648,014 - 9,656,429 (-)NCBIHuRef
CHM1_1129,874,021 - 9,882,437 (-)NCBICHM1_1
T2T-CHM13v2.0129,638,644 - 9,647,057 (-)NCBIT2T-CHM13v2.0
Cd69
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396129,244,287 - 129,252,332 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6129,244,288 - 129,252,399 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm386129,267,324 - 129,275,375 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6129,267,325 - 129,275,436 (-)Ensemblmm10GRCm38
MGSCv376129,217,343 - 129,225,387 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv366129,233,018 - 129,241,062 (-)NCBIMGSCv36mm8
Celera6130,989,995 - 130,998,041 (-)NCBICelera
Cytogenetic Map6F3NCBI
cM Map663.21NCBI
Cd69
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554135,579,072 - 5,587,491 (+)Ensembl
ChiLan1.0NW_0049554135,579,037 - 5,586,238 (+)NCBIChiLan1.0ChiLan1.0
CD69
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21015,243,088 - 15,251,508 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11215,239,847 - 15,248,267 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0129,800,446 - 9,808,874 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11210,049,668 - 10,058,094 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1210,049,668 - 10,058,094 (-)EnsemblpanPan2panpan1.1
CD69
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12736,197,202 - 36,205,045 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2736,197,175 - 36,204,597 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2710,416,968 - 10,424,807 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02736,545,864 - 36,553,699 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2736,545,852 - 36,553,251 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12736,429,091 - 36,436,930 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02736,456,497 - 36,464,333 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0279,942,252 - 9,950,090 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
CD69
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl562,077,988 - 62,085,900 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1562,078,134 - 62,084,961 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2564,909,979 - 64,916,924 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap5q25NCBI
CD69
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1119,659,154 - 9,666,342 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl119,659,029 - 9,665,914 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660891,735,439 - 1,742,246 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cd69
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248604,345,232 - 4,365,817 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248604,345,497 - 4,364,251 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Cd69
241 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:363
Count of miRNA genes:199
Interacting mature miRNAs:237
Transcripts:ENSRNOT00000010422
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4146370897184426481Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4134095016179095016Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4149763204169799698Rat
6478757Anxrr44Anxiety related response QTL 440.01087locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4146370897184426481Rat
1358364Sradr4Stress Responsive Adrenal Weight QTL 44.92adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)4131384565176384565Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4123870974168870974Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4140059299181024663Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4157292416184426481Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4106848959168870974Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)494638356168870820Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4127263297172263297Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4126334185171334185Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4147299608184426481Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
6478782Anxrr52Anxiety related response QTL 520.02091locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4124700988169700988Rat
6478720Alc23Alcohol consumption QTL 230.00509drinking behavior trait (VT:0001422)ethanol drink intake rate to body weight ratio (CMO:0001616)4155834926184426481Rat
6478785Anxrr53Anxiety related response QTL 530.01397locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)4100752691179366077Rat
1581566Eae21Experimental allergic encephalomyelitis QTL 216.2body mass (VT:0001259)maximum body weight loss to initial body weight ratio (CMO:0001400)4137447185182447185Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4137430611182430611Rat
6478728Anxrr36Anxiety related response QTL 360.01061locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)486709649168870974Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4134199006168870974Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4148121375176967367Rat
6478733Anxrr37Anxiety related response QTL 370.00095locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
6478737Anxrr38Anxiety related response QTL 380.00159locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4160623982184426481Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
12798525Anxrr57Anxiety related response QTL 573.210.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4148834094168870974Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 11 42 82 88 87 56 92 56 6 308 166 11 57 62 74 31 11 11

Sequence


Ensembl Acc Id: ENSRNOT00000091644   ⟹   ENSRNOP00000070664
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4164,411,485 - 164,419,339 (-)Ensembl
mRatBN7.2 Ensembl4162,725,446 - 162,733,300 (-)Ensembl
Rnor_6.0 Ensembl4163,041,141 - 163,049,084 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119283   ⟹   ENSRNOP00000078398
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4164,411,485 - 164,419,509 (-)Ensembl
mRatBN7.2 Ensembl4162,725,446 - 162,733,542 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000153540   ⟹   ENSRNOP00000105129
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4164,411,485 - 164,419,403 (-)Ensembl
RefSeq Acc Id: NM_134327   ⟹   NP_599154
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84164,411,485 - 164,419,403 (-)NCBI
mRatBN7.24162,725,446 - 162,733,364 (-)NCBI
Rnor_6.04163,041,147 - 163,049,065 (-)NCBI
Rnor_5.04211,685,114 - 211,693,033 (-)NCBI
RGSC_v3.44166,527,683 - 166,535,601 (-)RGD
Celera4151,413,397 - 151,421,315 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_599154 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH88219 (Get FASTA)   NCBI Sequence Viewer  
  AAL87637 (Get FASTA)   NCBI Sequence Viewer  
  ADK94898 (Get FASTA)   NCBI Sequence Viewer  
  EDM01751 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000070664.2
  ENSRNOP00000078398.2
  ENSRNOP00000105129
  ENSRNOP00000105129.1
RefSeq Acc Id: NP_599154   ⟸   NM_134327
- UniProtKB: Q5M851 (UniProtKB/TrEMBL),   D9Z4I9 (UniProtKB/TrEMBL),   A0A8I6G1Q9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070664   ⟸   ENSRNOT00000091644
Ensembl Acc Id: ENSRNOP00000078398   ⟸   ENSRNOT00000119283
Ensembl Acc Id: ENSRNOP00000105129   ⟸   ENSRNOT00000153540
Protein Domains
C-type lectin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5M851-F1-model_v2 AlphaFold Q5M851 1-199 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693432
Promoter ID:EPDNEW_R3957
Type:single initiation site
Name:Cd69_1
Description:Cd69 molecule
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04163,049,085 - 163,049,145EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61318 AgrOrtholog
BioCyc Gene G2FUF-42795 BioCyc
Ensembl Genes ENSRNOG00000056783 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000091644.3 UniProtKB/TrEMBL
  ENSRNOT00000119283.2 UniProtKB/TrEMBL
  ENSRNOT00000153540 ENTREZGENE
  ENSRNOT00000153540.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.100.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7384461 IMAGE-MGC_LOAD
InterPro C-type_lectin UniProtKB/TrEMBL
  C-type_lectin-like UniProtKB/TrEMBL
  C-type_lectin/matrix_domain UniProtKB/TrEMBL
  C-type_lectin_fold UniProtKB/TrEMBL
  NKR-like_CTLD UniProtKB/TrEMBL
KEGG Report rno:29187 UniProtKB/TrEMBL
MGC_CLONE MGC:108945 IMAGE-MGC_LOAD
NCBI Gene 29187 ENTREZGENE
PANTHER C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 UniProtKB/TrEMBL
  EARLY ACTIVATION ANTIGEN CD69 UniProtKB/TrEMBL
Pfam Lectin_C UniProtKB/TrEMBL
PhenoGen Cd69 PhenoGen
PROSITE C_TYPE_LECTIN_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000056783 RatGTEx
SMART CLECT UniProtKB/TrEMBL
Superfamily-SCOP C-type_lectin_fold UniProtKB/TrEMBL
UniProt A0A0G2JYI2_RAT UniProtKB/TrEMBL
  A0A8I6G1Q9 ENTREZGENE, UniProtKB/TrEMBL
  D9Z4I9 ENTREZGENE, UniProtKB/TrEMBL
  Q5M851 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-29 Cd69  Cd69 molecule  Cd69  CD69 antigen  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Cd69  CD69 antigen      Symbol and Name status set to approved 70585 APPROVED
2001-10-22 Cd69  CD69 antigen      Name updated 68916 PENDING

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction binds calcium 634727
gene_product member of the C-type lectin family 634727