Defa5-ps2 (defensin alpha 5, pseudogene 2) - Rat Genome Database

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Gene: Defa5-ps2 (defensin alpha 5, pseudogene 2) Rattus norvegicus
Analyze
Symbol: Defa5-ps2
Name: defensin alpha 5, pseudogene 2
RGD ID: 41289242
Description: Predicted to be involved in defense response to fungus and killing of cells of another organism. Predicted to be located in extracellular space.
Type: pseudo (Ensembl: protein-coding)
RefSeq Status: MODEL
Previously known as: Defa12-ps; ENSRNOG00000062701; LOC120097536; neutrophil antibiotic peptide NP-2-like
Related Functional Gene: Defa5  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81677,094,241 - 77,095,164 (-)NCBIGRCr8
mRatBN7.21670,391,781 - 70,392,695 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1670,391,781 - 70,392,695 (-)NCBImRatBN7.2 Ensembl
mRatBN7.2 Ensembl1670,391,781 - 70,392,695 (-)EnsemblmRatBN7.2 Ensembl
Cytogenetic Map16q12.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:15494476  


Genomics

Variants

.
Variants in Defa5-ps2
10 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
70215Niddm29Non-insulin dependent diabetes mellitus QTL 293.54blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)161900443575226532Rat
1578768Stresp22Stress response QTL 222.8thymus mass (VT:0004954)thymus wet weight (CMO:0000855)163528887080288870Rat
2293690Bss45Bone structure and strength QTL 455.130.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)163775215682752156Rat
2300163Bmd64Bone mineral density QTL 645.30.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)163775215682752156Rat
7205510Activ5Activity QTL 53.780.00028locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)164239634584729064Rat
8694429Bw164Body weight QTL 16450.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)165272646484729064Rat
8694364Abfw7Abdominal fat weight QTL 712.220.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)165272646484729064Rat
7411648Foco22Food consumption QTL 22150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)165272646484729064Rat
631525Pia14Pristane induced arthritis QTL 144.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)165571108783402471Rat
1298527Arunc2Aerobic running capacity QTL 22.9exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)166853271675029966Rat


Expression


Sequence

Nucleotide Sequences
GenBank Nucleotide AY746422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000088257   ⟹   ENSRNOP00000072461
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1670,391,781 - 70,392,695 (-)Ensembl
Protein Sequences
Ensembl Protein ENSRNOP00000072461.2
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000072461   ⟸   ENSRNOT00000088257
Protein Domains
Mammalian defensins

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-10835 BioCyc
Ensembl Genes ENSRNOG00000062701 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000088257.2 UniProtKB/TrEMBL
InterPro Alpha-defensin UniProtKB/TrEMBL
  Alpha-defensin_C UniProtKB/TrEMBL
  Defensin_beta/alpha UniProtKB/TrEMBL
NCBI Gene LOC120097536 ENTREZGENE
PANTHER DEFENSIN ALPHA 10-RELATED UniProtKB/TrEMBL
  PTHR11876 UniProtKB/TrEMBL
Pfam Defensin_1 UniProtKB/TrEMBL
PhenoGen Defa5-ps2 PhenoGen
PIRSF Alpha-defensin UniProtKB/TrEMBL
PROSITE DEFENSIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000062701 RatGTEx
SMART DEFSN UniProtKB/TrEMBL
Superfamily-SCOP Defensin-like UniProtKB/TrEMBL
UniProt A0A0G2K311_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-10 Defa5-ps2  defensin alpha 5, pseudogene 2  LOC120097536  neutrophil antibiotic peptide NP-2-like  Symbol and Name Changed 1299863 APPROVED
2022-06-02 LOC120097536  neutrophil antibiotic peptide NP-2-like  ENSRNOG00000062701    Data merged from RGD:150342570 737654 PROVISIONAL
2021-08-31 ENSRNOG00000062701        Symbol and Name status set to provisional 45752 PROVISIONAL
2021-01-27 LOC120097536  neutrophil antibiotic peptide NP-2-like      Symbol and Name status set to provisional 70820 PROVISIONAL