RT1-O1l1 (RT1 class Ib, locus O1 like 1) - Rat Genome Database

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Gene: RT1-O1l1 (RT1 class Ib, locus O1 like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: RT1-O1l1
Name: RT1 class Ib, locus O1 like 1
RGD ID: 41288091
Description: Predicted to enable peptide antigen binding activity and signaling receptor binding activity. Predicted to be involved in several processes, including antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent; antigen processing and presentation of endogenous peptide antigen via MHC class Ib; and positive regulation of T cell mediated cytotoxicity. Predicted to be located in lumenal side of endoplasmic reticulum membrane and phagocytic vesicle membrane. Predicted to be part of MHC class I protein complex. Predicted to be active in external side of plasma membrane and extracellular space.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: H-2 class I histocompatibility antigen, Q7 alpha chain-like; H-2 class I histocompatibility antigen, Q9 alpha chain-like; LOC120093125
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8202,627,434 - 2,664,895 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.2202,624,073 - 2,658,023 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl202,623,953 - 2,692,081 (+)EnsemblmRatBN7.2
Cytogenetic Map20p12NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.

Genomics

Variants

.
Variants in RT1-O1l1
602 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2306850Pia40Pristane induced arthritis QTL 400.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2015332005306452Rat
61474Eae1Experimental allergic encephalomyelitis QTL 13nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)2016693431Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20126925056Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20133724594Rat
7387283Uae44Urinary albumin excretion QTL 440.1712urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)20126128279Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600300Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20153308346533083Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124164241Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20134066551Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129193376Rat
70154Insul2Insulin level QTL 23.75blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)2016693431Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20127341128Rat
724519Bp144Blood pressure QTL 1440.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2013629303Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129193376Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129193376Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129193376Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129193376Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20114100378Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578510Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600300Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
7 1 11 45 66 130 87 11 42 36 32 14 14

Sequence


RefSeq Acc Id: XM_039099255   ⟹   XP_038955183
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8202,627,434 - 2,631,799 (+)NCBI
mRatBN7.2202,624,073 - 2,626,979 (+)NCBI
RefSeq Acc Id: XM_039099256   ⟹   XP_038955184
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8202,627,434 - 2,640,738 (+)NCBI
mRatBN7.2202,624,073 - 2,636,874 (+)NCBI
RefSeq Acc Id: XM_039099257   ⟹   XP_038955185
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8202,627,434 - 2,664,895 (+)NCBI
mRatBN7.2202,624,073 - 2,658,023 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038955183 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955184 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955185 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000098081.2
  ENSRNOP00000105343
  ENSRNOP00000105343.1
RefSeq Acc Id: XP_038955185   ⟸   XM_039099257
- UniProtKB: A0A8J8Y6P7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955184   ⟸   XM_039099256
- UniProtKB: A0A8J8Y6P7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955183   ⟸   XM_039099255
- UniProtKB: A0A8J8Y6P7 (UniProtKB/TrEMBL)

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:41288091 AgrOrtholog
BioCyc Gene G2FUF-4825 BioCyc
Ensembl Genes ENSRNOG00000031607 Ensembl
  ENSRNOG00000082801 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000036147 ENTREZGENE
  ENSRNOT00000036147.9 UniProtKB/TrEMBL
  ENSRNOT00000120399.2 UniProtKB/TrEMBL
NCBI Gene LOC120093125 ENTREZGENE
PhenoGen RT1-O1l1 PhenoGen
RatGTEx ENSRNOG00000031607 RatGTEx
  ENSRNOG00000082801 RatGTEx
UniProt A0A8J8Y6P7 ENTREZGENE
  A0ABK0L346_RAT UniProtKB/TrEMBL
  A0ABK0L5Z4_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 RT1-O1l1  RT1 class Ib, locus O1 like 1  LOC120093125  H-2 class I histocompatibility antigen, Q7 alpha chain-like  Symbol and Name Changed 1299863 APPROVED
2021-01-27 LOC120093125  H-2 class I histocompatibility antigen, Q7 alpha chain-like      Symbol and Name status set to provisional 70820 PROVISIONAL