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Gene: Rgs7 (regulator of G-protein signaling 7) Rattus norvegicus

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Symbol:

Rgs7

Name:

regulator of G-protein signaling 7

RGD ID:

3570

Description:

Enables G-protein alpha-subunit binding activity and G-protein beta-subunit binding activity. Involved in several processes, including positive regulation of potassium ion transmembrane transport; response to amphetamine; and response to ethanol. Located in nuclear envelope. Part of protein-containing complex. Orthologous to human RGS7 (regulator of G protein signaling 7); PARTICIPATES IN dopamine signaling pathway via D1 family of receptors; dopamine signaling pathway via D2 family of receptors; G protein mediated signaling pathway via Galphai family; INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RGS7 (regulator of G protein signaling 7)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Rgs7 (regulator of G protein signaling 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rgs7 (regulator of G protein signaling 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RGS7 (regulator of G protein signaling 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RGS7 (regulator of G protein signaling 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rgs7 (regulator of G protein signaling 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RGS7 (regulator of G protein signaling 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RGS7 (regulator of G protein signaling 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rgs7 (regulator of G protein signaling 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Rgs7 (regulator of G protein signaling 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	RGS7 (regulator of G protein signaling 7)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rgs7 (regulator of G protein signaling 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rgs7a (regulator of G protein signaling 7a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rgs7a (regulator of G protein signaling 7a)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rgs7b (regulator of G protein signaling 7b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rgs7b (regulator of G protein signaling 7b)	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	egl-10	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	egl-10	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	RSG7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	RSG7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rgs6	Alliance	DIOPT (InParanoid\|OrthoInspector\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	89,511,492 - 89,941,082 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	89,511,150 - 89,940,987 (-)	Ensembl				GRCr8
mRatBN7.2	13	86,979,269 - 87,408,834 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	86,979,279 - 87,408,888 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	89,484,142 - 89,917,175 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	90,884,436 - 91,317,445 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	88,061,466 - 88,488,430 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	93,095,659 - 93,534,452 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	93,095,200 - 93,307,199 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	97,560,710 - 97,998,950 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	90,732,429 - 91,210,368 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	86,580,200 - 87,006,930 (-)	NCBI		Celera
RGSC_v3.1	13	90,921,312 - 91,400,404 (-)	NCBI
Cytogenetic Map	13	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Experimental Seizures (IEP)

intellectual disability (ISO)

morphine dependence (ISO)

stroke (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,3,5-trinitro-1,3,5-triazinane (EXP)

17beta-estradiol (EXP,ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

ammonium chloride (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

Azoxymethane (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (EXP)

CGP 52608 (ISO)

cisplatin (ISO)

clozapine (EXP)

copper atom (EXP,ISO)

copper(0) (EXP,ISO)

curcumin (ISO)

dextran sulfate (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

entinostat (ISO)

ethanol (ISO)

fulvestrant (ISO)

genistein (ISO)

lead(0) (ISO)

maneb (ISO)

mercury dibromide (ISO)

methapyrilene (ISO)

methotrexate (ISO)

methoxychlor (EXP)

mono(2-ethylhexyl) phthalate (ISO)

morphine (ISO)

okadaic acid (ISO)

olanzapine (EXP)

p-chloromercuribenzoic acid (ISO)

paracetamol (ISO)

paraquat (ISO)

phenylmercury acetate (ISO)

potassium chromate (ISO)

quercetin (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

temozolomide (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichostatin A (ISO)

valproic acid (ISO)

vinclozolin (EXP)

WIN 55212-2 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

G protein-coupled receptor signaling pathway (IBA,IEA,ISO)

intracellular signal transduction (IEA)

negative regulation of G protein-coupled receptor signaling pathway (ISO,ISS)

negative regulation of signal transduction (IEA)

positive regulation of GTPase activity (ISO)

positive regulation of potassium ion transmembrane transport (IDA)

regulation of G protein-coupled receptor signaling pathway (IDA,IEA,ISO)

regulation of monoatomic cation transmembrane transport (IEA)

regulation of postsynaptic membrane potential (ISO)

response to amphetamine (IEP)

response to ethanol (IEP)

Cellular Component

cell tip (ISO)

cytoplasm (IBA,IEA)

cytosol (IEA,ISO)

dendrite (ISO)

dendrite terminus (ISO)

glutamatergic synapse (ISO)

membrane (IEA)

neuron projection (IBA)

nuclear envelope (IDA)

nucleus (ISO)

plasma membrane (IBA,IEA,ISO)

postsynaptic membrane (ISO)

presynapse (ISO)

presynaptic membrane (ISO)

protein-containing complex (IDA)

Molecular Function

G-protein alpha-subunit binding (IDA,ISO)

G-protein beta-subunit binding (IPI,ISO)

GTPase activator activity (IBA,IEA,ISO,ISS)

protein binding (IPI,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

dopamine signaling pathway via D1 family of receptors (ISO)

dopamine signaling pathway via D2 family of receptors (ISO)

G protein mediated signaling pathway via Galphai family (ISO)

G protein mediated signaling pathway via Galphas family (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	The physiology, signaling, and pharmacology of dopamine receptors.	Beaulieu JM and Gainetdinov RR, Pharmacol Rev. 2011 Mar;63(1):182-217. doi: 10.1124/pr.110.002642. Epub 2011 Feb 8.
2.	A region-specific increase in Galphaq and Galpha11 proteins in brains of rats during cocaine withdrawal.	Carrasco GA, etal., J Pharmacol Exp Ther. 2003 Dec;307(3):1012-9. Epub 2003 Oct 8.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
5.	Regulation of regulators of G protein signaling mRNA expression in rat brain by acute and chronic electroconvulsive seizures.	Gold SJ, etal., J Neurochem. 2002 Aug;82(4):828-38.
6.	Postnatal induction and localization of R7BP, a membrane-anchoring protein for regulator of G protein signaling 7 family-Gbeta5 complexes in brain.	Grabowska D, etal., Neuroscience. 2008 Feb 19;151(4):969-82. doi: 10.1016/j.neuroscience.2007.11.045. Epub 2007 Dec 8.
7.	Spinal cord injury induces expression of RGS7 in microglia/macrophages in rats.	Hausmann ON, etal., Eur J Neurosci. 2002 Feb;15(4):602-12.
8.	Expression of RGS2, RGS4 and RGS7 in the developing postnatal brain.	Ingi T and Aoki Y, Eur J Neurosci. 2002 Mar;15(5):929-36.
9.	Chronic cold exposure increases RGS7 expression and decreases alpha(2)-autoreceptor-mediated inhibition of noradrenergic locus coeruleus neurons.	Jedema HP, etal., Eur J Neurosci. 2008 May;27(9):2433-43.
10.	EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins.	Koelle MR and Horvitz HR, Cell 1996 Jan 12;84(1):115-25.
11.	Chronic intermittent ethanol exposure selectively alters the expression of Ga subunit isoforms and RGS subtypes in rat prefrontal cortex.	Luessen DJ, etal., Brain Res. 2017 Oct 1;1672:106-112. doi: 10.1016/j.brainres.2017.07.014. Epub 2017 Jul 21.
12.	Expression of neural RGS-R7 and Gbeta5 Proteins in Response to Acute and Chronic Morphine.	López-Fando A, etal., Neuropsychopharmacology. 2005 Jan;30(1):99-110. doi: 10.1038/sj.npp.1300515.
13.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
14.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
15.	GOA pipeline	RGD automated data pipeline
16.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
17.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
18.	RGS7 and RGS8 differentially accelerate G protein-mediated modulation of K+ currents.	Saitoh O, etal., J Biol Chem 1999 Apr 2;274(14):9899-904.
19.	The brain gene expression profile of dopamine D2/D3 receptors and associated signaling proteins following amphetamine self-administration.	Sun H, etal., Neuroscience. 2015 Oct 29;307:253-61. doi: 10.1016/j.neuroscience.2015.08.053. Epub 2015 Aug 28.
20.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
21.	Complexes of the G protein subunit gbeta 5 with the regulators of G protein signaling RGS7 and RGS9. Characterization in native tissues and in transfected cells.	Witherow DS, etal., J Biol Chem. 2000 Aug 11;275(32):24872-80.

Additional References at PubMed

PMID:9315921	PMID:10521509	PMID:15897264	PMID:19376773	PMID:21343290	PMID:22689652	PMID:22871113	PMID:24755289	PMID:27965545

Genomics

Comparative Map Data

Rgs7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	89,511,492 - 89,941,082 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	89,511,150 - 89,940,987 (-)	Ensembl				GRCr8
mRatBN7.2	13	86,979,269 - 87,408,834 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	86,979,279 - 87,408,888 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	89,484,142 - 89,917,175 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	90,884,436 - 91,317,445 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	88,061,466 - 88,488,430 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	93,095,659 - 93,534,452 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	93,095,200 - 93,307,199 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	97,560,710 - 97,998,950 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	90,732,429 - 91,210,368 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	86,580,200 - 87,006,930 (-)	NCBI		Celera
RGSC_v3.1	13	90,921,312 - 91,400,404 (-)	NCBI
Cytogenetic Map	13	q24	NCBI

RGS7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	240,774,742 - 241,357,230 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	240,767,636 - 241,357,374 (-)	Ensembl			hg38	GRCh38
GRCh37	1	240,938,042 - 241,520,530 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	239,005,440 - 239,587,101 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	1	237,264,911 - 237,846,519	NCBI
Celera	1	214,195,486 - 214,775,530 (-)	NCBI		Celera
Cytogenetic Map	1	q43	NCBI
HuRef	1	211,396,767 - 211,978,931 (-)	NCBI		HuRef
CHM1_1	1	242,211,139 - 242,793,223 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	240,186,136 - 240,768,709 (-)	NCBI		T2T-CHM13v2.0

Rgs7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	174,886,642 - 175,320,287 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	174,886,653 - 175,320,066 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	1	175,059,076 - 175,492,862 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	175,059,087 - 175,492,500 (-)	Ensembl			mm10	GRCm38
MGSCv37	1	176,989,207 - 177,422,676 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	1	176,895,892 - 177,329,065 (-)	NCBI		MGSCv36	mm8
Celera	1	182,147,940 - 182,583,035 (-)	NCBI		Celera
Cytogenetic Map	1	H3	NCBI
cM Map	1	81.11	NCBI

Rgs7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	10,670,009 - 11,127,757 (+)	Ensembl
ChiLan1.0	NW_004955406	10,669,127 - 11,127,564 (+)	NCBI	ChiLan1.0	ChiLan1.0

RGS7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	7,788,859 - 8,380,229 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	8,013,025 - 8,603,631 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	216,329,373 - 216,919,898 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	221,313,329 - 221,899,673 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	221,313,924 - 221,899,627 (-)	Ensembl			panPan2	panpan1.1

RGS7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	32,296,337 - 32,792,085 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	32,296,695 - 32,792,036 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	31,844,360 - 32,355,859 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	32,121,410 - 32,620,141 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	32,121,410 - 32,618,757 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	31,959,165 - 32,454,995 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	31,990,446 - 32,479,343 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	32,231,779 - 32,720,515 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Rgs7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	45,194,086 - 45,660,702 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936526	9,088,350 - 9,551,899 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936526	9,087,820 - 9,552,482 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RGS7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	11,950,901 - 12,322,359 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	10	11,950,897 - 12,322,382 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	14,263,678 - 14,421,091 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RGS7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	77,876,831 - 78,444,732 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	77,876,833 - 78,191,928 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666055	79,989,999 - 80,571,537 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rgs7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624771	11,206,421 - 11,723,749 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624771	11,205,772 - 11,724,980 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Rgs7
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	10	53,610,007 - 53,800,301 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Rgs7
2336 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	93
Count of miRNA genes:	74
Interacting mature miRNAs:	85
Transcripts:	ENSRNOT00000065041
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	21120177	109350286	Rat
738027	Lnnr6	Liver neoplastic nodule remodeling QTL 6	3.3		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	13	65613454	109350286	Rat
7387280	Uae43	Urinary albumin excretion QTL 43	5.69	0.4174	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	68983334	109350286	Rat
1298066	Bp159	Blood pressure QTL 159		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	48639634	93639634	Rat
10755495	Bp387	Blood pressure QTL 387	3.78		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	37216241	90057603	Rat
2293702	Bss34	Bone structure and strength QTL 34	4.61	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	13	67635937	109350286	Rat
1576318	Schws5	Schwannoma susceptibility QTL 5		0.0351	nervous system integrity trait (VT:0010566)	post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)	13	64497900	109350286	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	11081740	103588154	Rat
1354655	Bp241	Blood pressure QTL 241	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	38975045	103588154	Rat
8655951	Rf63	Renal function QTL 63	12.2		blood urea nitrogen amount (VT:0005265)	plasma urea nitrogen level (CMO:0000586)	13	71610804	109350286	Rat
4889606	Gluco63	Glucose level QTL 63	2.86	0.003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	13	83286150	109350286	Rat
8655959	Pur32	Proteinuria QTL 32	8.4		urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	72984506	99745408	Rat
1302791	Stl29	Serum triglyceride level QTL 29	3.3	0.0011	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	13	89333129	92500981	Rat
2293687	Bss26	Bone structure and strength QTL 26	4.6	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	13	67635937	109350286	Rat
12879475	Bp400	Blood pressure QTL 400			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	64375743	109350286	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	103588154	Rat
724564	Uae11	Urinary albumin excretion QTL 11	5.7		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	13	47354258	94285672	Rat
2293341	Glom15	Glomerulus QTL 15	9.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	13	67635937	109350286	Rat

Markers in Region

D13Rat187

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	13	89,773,194 - 89,773,402 (+)	Marker Load Pipeline
mRatBN7.2	13	87,240,998 - 87,241,206 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	93,368,290 - 93,368,497	NCBI	Rnor6.0
Rnor_5.0	13	97,832,701 - 97,832,908	UniSTS	Rnor5.0
RGSC_v3.4	13	91,043,346 - 91,043,554	RGD	RGSC3.4
RGSC_v3.4	13	91,043,347 - 91,043,554	UniSTS	RGSC3.4
Celera	13	86,839,776 - 86,839,983	UniSTS
RGSC_v3.1	13	91,232,231 - 91,232,438	RGD
RH 3.4 Map	13	583.4	UniSTS
RH 3.4 Map	13	583.4	RGD
RH 2.0 Map	13	633.1	RGD
SHRSP x BN Map	13	40.7498	RGD
Cytogenetic Map	13	q24-q25	UniSTS

D13Uia7

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	87,311,410 - 87,311,565 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	93,438,419 - 93,438,573	NCBI	Rnor6.0
Rnor_5.0	13	97,902,797 - 97,902,951	UniSTS	Rnor5.0
RGSC_v3.4	13	91,113,973 - 91,114,128	RGD	RGSC3.4
RGSC_v3.4	13	91,113,974 - 91,114,128	UniSTS	RGSC3.4
Celera	13	86,910,157 - 86,910,311	UniSTS
RGSC_v3.1	13	91,302,857 - 91,303,012	RGD
Cytogenetic Map	13	q24-q25	UniSTS

D13Mco21

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	13	89,744,312 - 89,744,427 (+)	Marker Load Pipeline
mRatBN7.2	13	87,212,117 - 87,212,232 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	93,340,676 - 93,340,790	NCBI	Rnor6.0
Rnor_5.0	13	97,805,084 - 97,805,198	UniSTS	Rnor5.0
RGSC_v3.4	13	91,012,798 - 91,012,913	RGD	RGSC3.4
RGSC_v3.4	13	91,012,799 - 91,012,913	UniSTS	RGSC3.4
Celera	13	86,812,654 - 86,812,768	UniSTS
RGSC_v3.1	13	91,201,682 - 91,201,797	RGD
Cytogenetic Map	13	q24-q25	UniSTS

D13Ulb2

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	87,016,284 - 87,016,569 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	93,132,654 - 93,132,936	NCBI	Rnor6.0
Rnor_5.0	13	97,597,607 - 97,597,889	UniSTS	Rnor5.0
RGSC_v3.4	13	90,769,328 - 90,769,610	UniSTS	RGSC3.4
Celera	13	86,617,203 - 86,617,485	UniSTS
Cytogenetic Map	13	q24-q25	UniSTS

RH131359

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	86,979,344 - 86,979,548 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	93,095,723 - 93,095,926	NCBI	Rnor6.0
Rnor_5.0	13	97,560,774 - 97,560,977	UniSTS	Rnor5.0
RGSC_v3.4	13	90,732,493 - 90,732,696	UniSTS	RGSC3.4
Celera	13	86,580,264 - 86,580,467	UniSTS
RH 3.4 Map	13	585.8	UniSTS
Cytogenetic Map	13	q24-q25	UniSTS

RH134962

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	87,358,211 - 87,358,361 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	93,485,214 - 93,485,363	NCBI	Rnor6.0
Rnor_5.0	13	97,949,592 - 97,949,741	UniSTS	Rnor5.0
RGSC_v3.4	13	91,160,769 - 91,160,918	UniSTS	RGSC3.4
Celera	13	86,956,950 - 86,957,099	UniSTS
RH 3.4 Map	13	585.0	UniSTS
Cytogenetic Map	13	q24-q25	UniSTS

BF402644

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	87,365,385 - 87,365,492 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	93,492,388 - 93,492,494	NCBI	Rnor6.0
Rnor_5.0	13	97,956,766 - 97,956,872	UniSTS	Rnor5.0
RGSC_v3.4	13	91,167,943 - 91,168,049	UniSTS	RGSC3.4
Celera	13	86,964,065 - 86,964,171	UniSTS
RH 3.4 Map	13	583.4	UniSTS
Cytogenetic Map	13	q24-q25	UniSTS

AU046960

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	87,370,449 - 87,370,564 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	93,497,409 - 93,497,523	NCBI	Rnor6.0
Rnor_5.0	13	97,961,812 - 97,961,926	UniSTS	Rnor5.0
RGSC_v3.4	13	91,173,326 - 91,173,440	UniSTS	RGSC3.4
Celera	13	86,969,125 - 86,969,239	UniSTS
Cytogenetic Map	13	q24-q25	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
11	11	47	152	64	63	32	30	32	6	236	109	10	124	76	86	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_019343	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091028	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091029	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091030	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091031	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091032	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272559	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272560	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272561	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB024398	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC109958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U32328	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000065041 ⟹ ENSRNOP00000063631

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	89,511,492 - 89,711,971 (-)	Ensembl
mRatBN7.2 Ensembl	13	86,979,279 - 87,179,776 (-)	Ensembl
Rnor_6.0 Ensembl	13	93,095,200 - 93,307,199 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000106278 ⟹ ENSRNOP00000094085

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	89,519,259 - 89,940,987 (-)	Ensembl
mRatBN7.2 Ensembl	13	86,995,343 - 87,408,693 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000107041 ⟹ ENSRNOP00000076773

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	89,511,150 - 89,940,987 (-)	Ensembl
mRatBN7.2 Ensembl	13	86,979,490 - 87,408,888 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000112294 ⟹ ENSRNOP00000090982

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	89,511,492 - 89,940,987 (-)	Ensembl
mRatBN7.2 Ensembl	13	86,979,490 - 87,408,888 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000116817 ⟹ ENSRNOP00000082844

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	89,511,490 - 89,892,575 (-)	Ensembl
mRatBN7.2 Ensembl	13	86,979,279 - 87,408,609 (-)	Ensembl

RefSeq Acc Id:

NM_019343 ⟹ NP_062216

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	89,511,492 - 89,941,050 (-)	NCBI
mRatBN7.2	13	86,979,279 - 87,408,825 (-)	NCBI
Rnor_6.0	13	93,095,659 - 93,534,452 (-)	NCBI
Rnor_5.0	13	97,560,710 - 97,998,950 (-)	NCBI
RGSC_v3.4	13	90,732,429 - 91,210,368 (-)	RGD
Celera	13	86,580,200 - 87,006,930 (-)	RGD

Sequence:

show sequence

TGAGGCCGCCTTGGCCGAGGAGGGCAGACTGATCATCCTTGTATCTGAGCTACCAAGTTCTGTG
TGAAATGGCTCAGGGGAATAATTATGGCCAGACCAGCAATGGGGTGGCAGAGGAATCACCGAAC
ATGCTGGTGTACAGAAAGATGGAAGATGTCATAGCACGTATGCAAGATGAAAAAAATGGAATTC
CCATCCGTACCGTCAAAAGCTTCCTTTCCAAGATCCCCAGTGTTTTCTCTGGGTCAGACATTGT
TCAGTGGTTAATAAAGAACTTAACTATAGAAGATCCAGTGGAGGCTCTCCATTTGGGAACGCTA
ATGGCTGCCCATGGCTACTTCTTTCCCATCTCAGATCATGTCCTCACACTCAAGGATGATGGCA
CCTTCTACCGGTTTCAAACACCCTATTTTTGGCCGTCAAATTGTTGGGAGCCAGAAAACACAGA
CTATGCTGTTTACCTCTGCAAGAGAACAATGCAAAACAAGGCAAGGCTAGAGCTAGCAGACTAC
GAAGCCGAGAGCCTGGCCAGGCTGCAGAGGGCATTTGCCCGGAAGTGGGAGTTCATTTTTATGC
AAGCAGAAGCACAAGCTAAAGTGGACAAGAAGAGGGACAAAATTGAAAGGAAGATCCTCGATAG
TCAGGAGAGAGCATTCTGGGATGTCCACAGGCCTGTGCCTGGGTGTGTAAATACTACAGAAGTG
GACATCAAGAAATCATCCCGGATGAGAAACCCACACAAAACACGCAAGTCTGTCTATGGTTTAC
AAAATGACATCCGAAGTCACAGTCCCACCCACACACCCACACCAGAAACCAAGCCTCCAACAGA
AGATGAGTTGCACCGACAGATAAAATACTGGCAAATACAGTTAGATAGACATCGGTTAAAAATG
TCAAAAGTTGCTGATAGTCTACTAAGTTATACGGAACAGTATGTAGAGTATGACCCATTTCTTG
TACCGCCTGACCCTTCCAACCCATGGCTCTCAGATGATACGACATTCTGGGAACTTGAAGCAAG
CAAAGAACCAAGTCAACAGAGGGTAAAACGATGGGGTTTTGGCATGGATGAGGCACTGAAAGAC
CCAGTTGGGAGAGAGCAGTTCCTTAAGTTTCTAGAATCAGAATTCAGCTCAGAGAACTTAAGGT
TCTGGTTGGCAGTGGAGGACCTGAAGAAAAGGCCTATCCGAGAGGTCCCCTCTCGAGTACAGGA
AATATGGCAAGAATTTCTGGCTCCGGGGGCCCCCAGTGCCATTAACTTGGATTCGAAGAGTTAT
GACAAGACCACACAGAATGTGAAGGAACCAGGACGATACACATTCGAAGATGCTCAGGAGCACA
TTTACAAGCTGATGAAGAGTGACTCATACCCCCGCTTTATAAGATCTAGTGCCTACCAGGAACT
TCTACAGGCAAAGAGAAAGGGCAGAAACATCCCTATTTTCCCATGCCATAAAAACTGTACACCA
ACACTGAGGGCCAGCACTAACCTGTTATGAAAAGAGGGGAAATCTCTCACATCCAAGAGGTTAA
CAAGCCTTGTTCAGTCTTACTAAAAGGATCGTCTTCGTCACATGAGAGCTGGACGGAGCCATCG
CCCATACCTTGTAGCCCATCGCGCTGTTACCTGGAGCCAAGGATGTTAGACCAAGATGTTGCAT
GAATGAAGGACCTGAGTTGTTCTGTGTGCACATAAAGGCATCACATTTGCCAAGGGACACTGTC
ATCTCATTGCCTCCATCTTCCCGTGCCGTTTGCTTCCCTCTCTCCTCGTACTAAGCTGGATCTG
TGTCCTTTTCTTTTTAACGAGTTCAAGTGAAGGAAAACTTTATTTGTCCCCCCTTCCTCTCTTT
TTCTTAAAGCTTCTGCTAGATGCACAGTTCACTGAAAATTCAGTCAGTCACAAACTGGAAGAAT
TGTAAAAGAAAAAAAAGTATACATCACTAAGTACACACGTGGCTTCACATCTATTAAATAATAA
ATTGGCATGGAAGGAAGGTGTCATTTCACCCGTGTATCCACAGTCTTAAGCAAGCGCCCATCTT
CATCTGTTCTCTGGACATTGTCTGTTCATGTTTCTTGCATTTATTTTTATACCATATTTAAATG
AGAAAACACCTTTTACTCCAGATGTATCAAAGTTGACCTCTTCTCTGTAAATTTGTGTATGTTT
ATATTGTTGTTTTATCTTTCATTAAAAGATGCAGAATCTC

hide sequence

RefSeq Acc Id:

XM_039091028 ⟹ XP_038946956

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	89,512,142 - 89,940,696 (-)	NCBI
mRatBN7.2	13	86,979,269 - 87,408,425 (-)	NCBI

RefSeq Acc Id:

XM_039091029 ⟹ XP_038946957

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	89,512,142 - 89,940,454 (-)	NCBI
mRatBN7.2	13	86,979,269 - 87,408,104 (-)	NCBI

RefSeq Acc Id:

XM_039091030 ⟹ XP_038946958

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	89,512,062 - 89,941,056 (-)	NCBI
mRatBN7.2	13	86,979,269 - 87,408,834 (-)	NCBI

RefSeq Acc Id:

XM_039091031 ⟹ XP_038946959

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	89,511,494 - 89,941,056 (-)	NCBI
mRatBN7.2	13	86,979,269 - 87,408,833 (-)	NCBI

RefSeq Acc Id:

XM_039091032 ⟹ XP_038946960

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	89,512,141 - 89,941,035 (-)	NCBI
mRatBN7.2	13	86,979,269 - 87,408,834 (-)	NCBI

RefSeq Acc Id:

XM_063272559 ⟹ XP_063128629

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	89,511,494 - 89,940,454 (-)	NCBI

RefSeq Acc Id:

XM_063272560 ⟹ XP_063128630

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	89,511,494 - 89,940,755 (-)	NCBI

RefSeq Acc Id:

XM_063272561 ⟹ XP_063128631

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	89,511,494 - 89,941,082 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_062216	(Get FASTA)	NCBI Sequence Viewer
	XP_038946956	(Get FASTA)	NCBI Sequence Viewer
	XP_038946957	(Get FASTA)	NCBI Sequence Viewer
	XP_038946958	(Get FASTA)	NCBI Sequence Viewer
	XP_038946959	(Get FASTA)	NCBI Sequence Viewer
	XP_038946960	(Get FASTA)	NCBI Sequence Viewer
	XP_063128629	(Get FASTA)	NCBI Sequence Viewer
	XP_063128630	(Get FASTA)	NCBI Sequence Viewer
	XP_063128631	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC52368	(Get FASTA)	NCBI Sequence Viewer
	BAA75635	(Get FASTA)	NCBI Sequence Viewer
	EDL94767	(Get FASTA)	NCBI Sequence Viewer
	EDL94768	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000076773
	ENSRNOP00000082844.1
	ENSRNOP00000090982
	ENSRNOP00000094085
GenBank Protein	P49803	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_062216 ⟸ NM_019343

- UniProtKB:

Q9R0R0 (UniProtKB/Swiss-Prot), P49803 (UniProtKB/Swiss-Prot), A6JGB2 (UniProtKB/TrEMBL), A0A8I6AKV4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAQGNNYGQTSNGVAEESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGSDIVQ
WLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNCWEPENTDY
AVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKKRDKIERKILDSQ
ERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSHSPTHTPTPETKPPTED
ELHRQIKYWQIQLDRHRLKMSKVADSLLSYTEQYVEYDPFLVPPDPSNPWLSDDTTFWELEASK
EPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENLRFWLAVEDLKKRPIREVPSRVQEI
WQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFEDAQEHIYKLMKSDSYPRFIRSSAYQELL
QAKRKGRNIPIFPCHKNCTPTLRASTNLL

hide sequence

Ensembl Acc Id:

ENSRNOP00000063631 ⟸ ENSRNOT00000065041

RefSeq Acc Id:	XP_038946960 ⟸ XM_039091032
- Peptide Label:	isoform X4
- UniProtKB:	A0A8I6AKV4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038946958 ⟸ XM_039091030
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I5YBW3 (UniProtKB/TrEMBL), A0A8I6AKV4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038946959 ⟸ XM_039091031
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I6AAQ8 (UniProtKB/TrEMBL), A6JGB1 (UniProtKB/TrEMBL), A0A8I6AKV4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038946956 ⟸ XM_039091028
- Peptide Label:	isoform X1
- UniProtKB:	P49803 (UniProtKB/Swiss-Prot), Q9R0R0 (UniProtKB/Swiss-Prot), A6JGB2 (UniProtKB/TrEMBL), A0A8I6AKV4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038946957 ⟸ XM_039091029
- Peptide Label:	isoform X1
- UniProtKB:	P49803 (UniProtKB/Swiss-Prot), Q9R0R0 (UniProtKB/Swiss-Prot), A6JGB2 (UniProtKB/TrEMBL), A0A8I6AKV4 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000082844 ⟸ ENSRNOT00000116817

Ensembl Acc Id:

ENSRNOP00000076773 ⟸ ENSRNOT00000107041

Ensembl Acc Id:

ENSRNOP00000090982 ⟸ ENSRNOT00000112294

Ensembl Acc Id:

ENSRNOP00000094085 ⟸ ENSRNOT00000106278

RefSeq Acc Id:	XP_063128631 ⟸ XM_063272561
- Peptide Label:	isoform X5
- UniProtKB:	A0A8I6AKV4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063128630 ⟸ XM_063272560
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I6AAQ8 (UniProtKB/TrEMBL), A6JGB1 (UniProtKB/TrEMBL), A0A8I6AKV4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063128629 ⟸ XM_063272559
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I6AAQ8 (UniProtKB/TrEMBL), A6JGB1 (UniProtKB/TrEMBL), A0A8I6AKV4 (UniProtKB/TrEMBL)

Protein Domains

DEP G protein gamma RGS

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P49803-F1-model_v2	AlphaFold	P49803	1-477	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:3570	AgrOrtholog
BioCyc Gene	G2FUF-17241	BioCyc
Ensembl Genes	ENSRNOG00000021984	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000106278	ENTREZGENE
	ENSRNOT00000107041	ENTREZGENE
	ENSRNOT00000112294	ENTREZGENE
	ENSRNOT00000116817.1	UniProtKB/Swiss-Prot
Gene3D-CATH	1.10.10.10	UniProtKB/Swiss-Prot
	1.10.1240.60	UniProtKB/Swiss-Prot
	1.10.167.10	UniProtKB/Swiss-Prot
	4.10.260.10	UniProtKB/Swiss-Prot
InterPro	DEP_dom	UniProtKB/Swiss-Prot
	G-protein_gamma-like_dom	UniProtKB/Swiss-Prot
	GGL_sf	UniProtKB/Swiss-Prot
	RGS	UniProtKB/Swiss-Prot
	RGS6/7/9/11	UniProtKB/Swiss-Prot
	RGS6/7/9/11_DHEX_sf	UniProtKB/Swiss-Prot
	RGS_DHEX	UniProtKB/Swiss-Prot
	RGS_sf	UniProtKB/Swiss-Prot
	RGS_subdomain_2	UniProtKB/Swiss-Prot
	WH-like_DNA-bd_sf	UniProtKB/Swiss-Prot
	WH_DNA-bd_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:54296	UniProtKB/Swiss-Prot
NCBI Gene	54296	ENTREZGENE
PANTHER	LP21163P	UniProtKB/Swiss-Prot
	REGULATOR OF G-PROTEIN SIGNALING 7	UniProtKB/Swiss-Prot
Pfam	DEP	UniProtKB/Swiss-Prot
	G-gamma	UniProtKB/Swiss-Prot
	RGS	UniProtKB/Swiss-Prot
	RGS_DHEX	UniProtKB/Swiss-Prot
PhenoGen	Rgs7	PhenoGen
PRINTS	RGSPROTEIN	UniProtKB/Swiss-Prot
PROSITE	DEP	UniProtKB/Swiss-Prot
	RGS	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000021984	RatGTEx
SMART	DEP	UniProtKB/Swiss-Prot
	G_gamma	UniProtKB/Swiss-Prot
	GGL	UniProtKB/Swiss-Prot
	RGS	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF46785	UniProtKB/Swiss-Prot
	SSF48097	UniProtKB/Swiss-Prot
	SSF48670	UniProtKB/Swiss-Prot
TIGR	TC208242
UniProt	A0A8I5YBW3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AAQ8	ENTREZGENE
	A0A8I6AKV4	ENTREZGENE, UniProtKB/TrEMBL
	A6JGB1	ENTREZGENE, UniProtKB/TrEMBL
	A6JGB2	ENTREZGENE, UniProtKB/TrEMBL
	D3ZWG2_RAT	UniProtKB/TrEMBL
	P49803	ENTREZGENE
	Q9R0R0	ENTREZGENE
	RGS7_RAT	UniProtKB/Swiss-Prot
UniProt Secondary	Q9R0R0	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2002-06-10	Rgs7	regulator of G-protein signaling 7			Name updated	70584	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

RGD Manual Annotations

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Imported Disease Annotations - CTD

RGD Manual Annotations