Rgs7 (regulator of G protein signaling 7) - Rat Genome Database

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Gene: Rgs7 (regulator of G protein signaling 7) Heterocephalus glaber
Analyze
Symbol: Rgs7
Name: regulator of G protein signaling 7
RGD ID: 18910033
Description: ENCODES a protein that exhibits G-protein alpha-subunit binding (ortholog); G-protein beta-subunit binding (ortholog); INVOLVED IN G protein-coupled receptor signaling pathway (ortholog); negative regulation of G protein-coupled receptor signaling pathway (ortholog); positive regulation of potassium ion transmembrane transport (ortholog); PARTICIPATES IN dopamine signaling pathway via D1 family of receptors; dopamine signaling pathway via D2 family of receptors; G protein mediated signaling pathway via Galphai family; ASSOCIATED WITH Experimental Seizures (ortholog); gastrointestinal stromal tumor (ortholog); Hereditary Leiomyomatosis and Renal Cell Cancer (ortholog); FOUND IN cell tip (ortholog); cytosol (ortholog); dendrite (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: regulator of G-protein signaling 7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477111,206,421 - 11,723,749 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477111,205,772 - 11,724,980 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Rgs7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477111,206,421 - 11,723,749 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477111,205,772 - 11,724,980 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
RGS7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381240,774,742 - 241,357,230 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1240,767,636 - 241,357,374 (-)EnsemblGRCh38hg38GRCh38
GRCh371240,938,042 - 241,520,530 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361239,005,440 - 239,587,101 (-)NCBINCBI36Build 36hg18NCBI36
Build 341237,264,911 - 237,846,519NCBI
Celera1214,195,486 - 214,775,530 (-)NCBICelera
Cytogenetic Map1q43NCBI
HuRef1211,396,767 - 211,978,931 (-)NCBIHuRef
CHM1_11242,211,139 - 242,793,223 (-)NCBICHM1_1
T2T-CHM13v2.01240,186,136 - 240,768,709 (-)NCBIT2T-CHM13v2.0
Rgs7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391174,886,642 - 175,320,287 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1174,886,653 - 175,320,066 (-)EnsemblGRCm39 Ensembl
GRCm381175,059,076 - 175,492,862 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1175,059,087 - 175,492,500 (-)EnsemblGRCm38mm10GRCm38
MGSCv371176,989,207 - 177,422,676 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361176,895,892 - 177,329,065 (-)NCBIMGSCv36mm8
Celera1182,147,940 - 182,583,035 (-)NCBICelera
Cytogenetic Map1H3NCBI
cM Map181.11NCBI
Rgs7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81389,511,492 - 89,941,082 (-)NCBIGRCr8
mRatBN7.21386,979,269 - 87,408,834 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1386,979,279 - 87,408,888 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1389,484,142 - 89,917,175 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01390,884,436 - 91,317,445 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01388,061,466 - 88,488,430 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01393,095,659 - 93,534,452 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1393,095,200 - 93,307,199 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01397,560,710 - 97,998,950 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41390,732,429 - 91,210,368 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11390,921,312 - 91,400,404 (-)NCBI
Celera1386,580,200 - 87,006,930 (-)NCBICelera
Cytogenetic Map13q24NCBI
Rgs7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540610,670,009 - 11,127,757 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540610,669,127 - 11,127,564 (+)NCBIChiLan1.0ChiLan1.0
RGS7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v217,788,859 - 8,380,229 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan118,013,025 - 8,603,631 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01216,329,373 - 216,919,898 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11221,313,329 - 221,899,673 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1221,313,924 - 221,899,627 (-)Ensemblpanpan1.1panPan2
RGS7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1732,296,337 - 32,792,085 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl732,296,695 - 32,792,036 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha731,844,360 - 32,355,859 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0732,121,410 - 32,620,141 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl732,121,410 - 32,618,757 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1731,959,165 - 32,454,995 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0731,990,446 - 32,479,343 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0732,231,779 - 32,720,515 (-)NCBIUU_Cfam_GSD_1.0
Rgs7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934445,194,086 - 45,660,702 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365269,088,350 - 9,551,899 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365269,087,820 - 9,552,482 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RGS7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1011,950,901 - 12,322,359 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11011,950,897 - 12,322,382 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21014,263,678 - 14,421,091 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RGS7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12577,876,831 - 78,444,732 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2577,876,833 - 78,191,928 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605579,989,999 - 80,571,537 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021265464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021265465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021265467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021265468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021265469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021265470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021265471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021265472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021265473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021265474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021265475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01050504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01050505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01050506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01050507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01050508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01050509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01050510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01050511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01050512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01050513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01050514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01050515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01050516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01050517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01050518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSHGLT00000011470   ⟹   ENSHGLP00000011343
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477111,206,421 - 11,723,749 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000011471   ⟹   ENSHGLP00000011344
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477111,206,421 - 11,228,361 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000011472   ⟹   ENSHGLP00000011345
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477111,213,159 - 11,723,749 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000011473   ⟹   ENSHGLP00000011346
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477111,213,159 - 11,233,472 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000011474   ⟹   ENSHGLP00000011347
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477111,222,608 - 11,723,749 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000011475   ⟹   ENSHGLP00000011348
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477111,222,608 - 11,233,412 (-)Ensembl
RefSeq Acc Id: XM_021265464   ⟹   XP_021121123
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477111,205,772 - 11,724,297 (-)NCBI
RefSeq Acc Id: XM_021265465   ⟹   XP_021121124
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477111,205,772 - 11,724,300 (-)NCBI
RefSeq Acc Id: XM_021265467   ⟹   XP_021121126
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477111,205,772 - 11,724,298 (-)NCBI
RefSeq Acc Id: XM_021265468   ⟹   XP_021121127
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477111,205,772 - 11,724,291 (-)NCBI
RefSeq Acc Id: XM_021265469   ⟹   XP_021121128
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477111,205,772 - 11,724,296 (-)NCBI
RefSeq Acc Id: XM_021265470   ⟹   XP_021121129
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477111,205,772 - 11,724,980 (-)NCBI
RefSeq Acc Id: XM_021265471   ⟹   XP_021121130
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477111,205,772 - 11,724,572 (-)NCBI
RefSeq Acc Id: XM_021265472   ⟹   XP_021121131
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477111,205,772 - 11,724,297 (-)NCBI
RefSeq Acc Id: XM_021265473   ⟹   XP_021121132
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477111,205,772 - 11,724,301 (-)NCBI
RefSeq Acc Id: XM_021265474   ⟹   XP_021121133
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477111,205,772 - 11,724,291 (-)NCBI
RefSeq Acc Id: XM_021265475   ⟹   XP_021121134
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477111,205,772 - 11,724,296 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021121129   ⟸   XM_021265470
- Peptide Label: isoform X6
- UniProtKB: G5BGU2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021121130   ⟸   XM_021265471
- Peptide Label: isoform X6
- UniProtKB: G5BGU2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021121132   ⟸   XM_021265473
- Peptide Label: isoform X8
- UniProtKB: G5BGU2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021121124   ⟸   XM_021265465
- Peptide Label: isoform X2
- UniProtKB: G5BGU2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021121126   ⟸   XM_021265467
- Peptide Label: isoform X3
- UniProtKB: G5BGU2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021121131   ⟸   XM_021265472
- Peptide Label: isoform X7
- UniProtKB: G5BGU2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021121123   ⟸   XM_021265464
- Peptide Label: isoform X1
- UniProtKB: G5BGU2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021121128   ⟸   XM_021265469
- Peptide Label: isoform X5
- UniProtKB: G5BGU2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021121134   ⟸   XM_021265475
- Peptide Label: isoform X10
- UniProtKB: G5BGU2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021121133   ⟸   XM_021265474
- Peptide Label: isoform X9
- UniProtKB: G5BGU2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021121127   ⟸   XM_021265468
- Peptide Label: isoform X4
- UniProtKB: G5BGU2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000011347   ⟸   ENSHGLT00000011474
RefSeq Acc Id: ENSHGLP00000011345   ⟸   ENSHGLT00000011472
RefSeq Acc Id: ENSHGLP00000011344   ⟸   ENSHGLT00000011471
RefSeq Acc Id: ENSHGLP00000011343   ⟸   ENSHGLT00000011470
RefSeq Acc Id: ENSHGLP00000011348   ⟸   ENSHGLT00000011475
RefSeq Acc Id: ENSHGLP00000011346   ⟸   ENSHGLT00000011473


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000008134 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000011470 ENTREZGENE
  ENSHGLT00000011472 ENTREZGENE
  ENSHGLT00000011474 ENTREZGENE
Gene3D-CATH 1.10.1240.60 UniProtKB/TrEMBL
  Regulator of G-protein Signalling 4, domain 2 UniProtKB/TrEMBL
  Transducin (heterotrimeric G protein), gamma chain UniProtKB/TrEMBL
  Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain UniProtKB/TrEMBL
InterPro DEP_dom UniProtKB/TrEMBL
  G-protein_gamma-like_dom UniProtKB/TrEMBL
  GGL_sf UniProtKB/TrEMBL
  RGS UniProtKB/TrEMBL
  RGS6/7/9/11 UniProtKB/TrEMBL
  RGS6/7/9/11_DHEX_sf UniProtKB/TrEMBL
  RGS_DHEX UniProtKB/TrEMBL
  RGS_sf UniProtKB/TrEMBL
  RGS_subdomain_2 UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene Rgs7 ENTREZGENE
PANTHER LP21163P UniProtKB/TrEMBL
  REGULATOR OF G-PROTEIN SIGNALING 7 UniProtKB/TrEMBL
Pfam DEP UniProtKB/TrEMBL
  G-gamma UniProtKB/TrEMBL
  RGS UniProtKB/TrEMBL
  RGS_DHEX UniProtKB/TrEMBL
PRINTS RGSPROTEIN UniProtKB/TrEMBL
PROSITE DEP UniProtKB/TrEMBL
  RGS UniProtKB/TrEMBL
SMART DEP UniProtKB/TrEMBL
  G_gamma UniProtKB/TrEMBL
  GGL UniProtKB/TrEMBL
  RGS UniProtKB/TrEMBL
Superfamily-SCOP Regulator of G-protein signaling, RGS UniProtKB/TrEMBL
  Transducin (heterotrimeric G protein), gamma chain UniProtKB/TrEMBL
  Winged helix' DNA-binding domain UniProtKB/TrEMBL
UniProt G5BGU2 ENTREZGENE, UniProtKB/TrEMBL