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Gene: Rgs6 (regulator of G-protein signaling 6) Rattus norvegicus

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Symbol:

Rgs6

Name:

regulator of G-protein signaling 6

RGD ID:

3569

Description:

Enables protein domain specific binding activity. Involved in positive regulation of neuron differentiation. Part of protein-containing complex. Human ortholog(s) of this gene implicated in alcohol dependence. Orthologous to human RGS6 (regulator of G protein signaling 6); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptor; INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	107,875,883 - 108,527,472 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	107,876,039 - 108,555,840 (+)	Ensembl				GRCr8
mRatBN7.2	6	102,264,451 - 102,796,311 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	102,264,447 - 102,824,753 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	102,420,755 - 102,953,980 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	102,719,975 - 103,253,217 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	102,089,444 - 102,622,685 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	6	109,248,226 - 109,776,683 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	6	108,657,734 - 109,186,199 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	6	106,451,331 - 106,979,787 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	6	105,603,650 - 106,132,124 (+)	NCBI		F344_StmMcwi
Rnor_6.0	6	106,310,442 - 106,598,668 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	106,496,992 - 106,602,139 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	114,636,387 - 114,736,790 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	106,470,420 - 106,964,581 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	100,100,895 - 100,625,650 (+)	NCBI		Celera
RGSC_v3.1	6	106,940,142 - 106,967,896 (+)	NCBI
Cytogenetic Map	6	q24-q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

alcohol dependence (ISO)

morphine dependence (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1-naphthyl isothiocyanate (EXP)

2,2',5,5'-tetrachlorobiphenyl (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2-palmitoylglycerol (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

amiodarone (ISO)

ammonium chloride (EXP)

atrazine (EXP)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (EXP)

Cuprizon (EXP)

doxorubicin (ISO)

fulvestrant (ISO)

genistein (ISO)

lead(0) (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methapyrilene (ISO)

methoxychlor (EXP)

mono(2-ethylhexyl) phthalate (ISO)

morphine (ISO)

N,N-diethyl-m-toluamide (EXP)

N-nitrosodiethylamine (EXP)

nickel atom (ISO)

paraquat (EXP)

perfluorohexanesulfonic acid (ISO)

perfluorononanoic acid (ISO)

permethrin (EXP)

phenethyl caffeate (EXP)

rotenone (EXP)

sodium arsenite (ISO)

sunitinib (ISO)

titanium dioxide (ISO)

triclosan (ISO)

triphenyl phosphate (ISO)

zidovudine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

G protein-coupled receptor signaling pathway (IEA)

intracellular signal transduction (IEA)

negative regulation of signal transduction (IEA)

positive regulation of GTPase activity (ISO,ISS)

positive regulation of neuron differentiation (IDA)

regulation of G protein-coupled receptor signaling pathway (IEA)

regulation of monoatomic cation transmembrane transport (IEA)

Cellular Component

cytoplasm (IEA)

cytosol (IEA,ISO,ISS)

membrane (IEA,ISO,ISS)

nucleoplasm (IEA,ISO)

nucleus (IEA)

plasma membrane (IEA)

protein-containing complex (IDA)

Molecular Function

GTPase activator activity (IEA,ISO,ISS)

protein binding (ISO)

protein domain specific binding (IPI)

Molecular Pathway Annotations Click to see Annotation Detail View

acetylcholine signaling pathway via muscarinic acetylcholine receptor (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	An association study revealed substantial effects of dominance, epistasis and substance dependence co-morbidity on alcohol dependence symptom count.	Chen G, etal., Addict Biol. 2017 Nov;22(6):1475-1485. doi: 10.1111/adb.12402. Epub 2016 May 5.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Regulators of G-protein signaling (RGS) proteins: region-specific expression of nine subtypes in rat brain.	Gold SJ, etal., J Neurosci 1997 Oct 15;17(20):8024-37.
5.	EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins.	Koelle MR and Horvitz HR, Cell 1996 Jan 12;84(1):115-25.
6.	RGS6 interacts with SCG10 and promotes neuronal differentiation. Role of the G gamma subunit-like (GGL) domain of RGS6.	Liu Z, etal., J Biol Chem 2002 Oct 4;277(40):37832-9. Epub 2002 Jul 24.
7.	Expression of neural RGS-R7 and Gbeta5 Proteins in Response to Acute and Chronic Morphine.	López-Fando A, etal., Neuropsychopharmacology. 2005 Jan;30(1):99-110. doi: 10.1038/sj.npp.1300515.
8.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
9.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
10.	GOA pipeline	RGD automated data pipeline
11.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
13.	RGS Proteins in Heart: Brakes on the Vagus.	Stewart A, etal., Front Physiol. 2012 Apr 13;3:95. doi: 10.3389/fphys.2012.00095. eCollection 2012.

Additional References at PubMed

PMID:10521509

Genomics

Comparative Map Data

Rgs6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	107,875,883 - 108,527,472 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	107,876,039 - 108,555,840 (+)	Ensembl				GRCr8
mRatBN7.2	6	102,264,451 - 102,796,311 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	102,264,447 - 102,824,753 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	102,420,755 - 102,953,980 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	102,719,975 - 103,253,217 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	102,089,444 - 102,622,685 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	6	109,248,226 - 109,776,683 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	6	108,657,734 - 109,186,199 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	6	106,451,331 - 106,979,787 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	6	105,603,650 - 106,132,124 (+)	NCBI		F344_StmMcwi
Rnor_6.0	6	106,310,442 - 106,598,668 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	106,496,992 - 106,602,139 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	114,636,387 - 114,736,790 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	106,470,420 - 106,964,581 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	100,100,895 - 100,625,650 (+)	NCBI		Celera
RGSC_v3.1	6	106,940,142 - 106,967,896 (+)	NCBI
Cytogenetic Map	6	q24-q31	NCBI

RGS6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	71,867,335 - 72,630,029 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	71,932,429 - 72,566,530 (+)	Ensembl			hg38	GRCh38
GRCh37	14	72,398,888 - 73,033,238 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	71,469,539 - 72,102,991 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	14	71,469,585 - 72,100,407	NCBI
Celera	14	52,462,976 - 53,096,417 (+)	NCBI		Celera
Cytogenetic Map	14	q24.2	NCBI
HuRef	14	52,565,478 - 53,199,765 (+)	NCBI		HuRef
CHM1_1	14	72,336,952 - 72,971,253 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	66,072,765 - 66,835,660 (+)	NCBI		T2T-CHM13v2.0

Rgs6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	82,663,325 - 83,208,835 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	82,635,066 - 83,208,830 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	12	82,616,551 - 83,162,061 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	82,588,292 - 83,162,056 (+)	Ensembl			mm10	GRCm38
MGSCv37	12	83,718,025 - 84,259,799 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	12	83,535,886 - 84,077,669 (+)	NCBI		MGSCv36	mm8
Celera	12	84,069,722 - 84,604,177 (+)	NCBI		Celera
Cytogenetic Map	12	D1	NCBI
cM Map	12	38.14	NCBI

Rgs6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955523	2,762,987 - 3,335,474 (-)	Ensembl
ChiLan1.0	NW_004955523	2,763,143 - 3,366,851 (-)	NCBI	ChiLan1.0	ChiLan1.0

RGS6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	73,042,379 - 73,677,406 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	72,258,892 - 72,893,920 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	52,511,846 - 53,146,872 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	71,377,567 - 72,012,766 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	71,409,701 - 72,008,988 (+)	Ensembl			panPan2	panpan1.1

RGS6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	45,392,246 - 45,975,073 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	45,438,239 - 46,009,049 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	45,077,684 - 45,656,669 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	45,630,187 - 46,197,033 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	45,654,256 - 46,194,458 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	45,301,232 - 45,866,115 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	45,329,999 - 45,882,332 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	45,692,998 - 46,272,644 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Rgs6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	30,144,323 - 30,732,878 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936488	1,361,310 - 1,921,353 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936488	1,336,075 - 1,924,635 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RGS6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	95,365,939 - 95,930,034 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	7	95,365,212 - 95,930,040 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

RGS6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	49,161,466 - 49,803,209 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	49,591,815 - 49,775,653 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666053	37,367,918 - 37,991,218 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rgs6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	28,829,698 - 29,411,779 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624734	28,830,254 - 29,436,945 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Rgs6
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	7	96,756,587 - 97,266,112 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Rgs6
3816 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	62
Count of miRNA genes:	56
Interacting mature miRNAs:	62
Transcripts:	ENSRNOT00000058181
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2293088	Iddm28	Insulin dependent diabetes mellitus QTL 28	5.21		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	6	68767270	135411972	Rat
1331799	Bp211	Blood pressure QTL 211	3.66407		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	88019181	136741135	Rat
1358355	Srcrt4	Stress Responsive Cort QTL 4	6.39		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	106095977	147156653	Rat
61329	Eae9	Experimental allergic encephalomyelitis QTL 9	3.7		body mass (VT:0001259)	change in body weight (CMO:0002045)	6	84490437	129490437	Rat
2313399	Anxrr28	Anxiety related response QTL 28			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	6	101593607	138161926	Rat
1331789	Rf37	Renal function QTL 37	3.224		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	6	86494122	112380234	Rat
1331725	Bp212	Blood pressure QTL 212	3.52475		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	99437079	125323237	Rat
1331722	Thshl1	Thyroid stimulating hormone level QTL 1	11.7	0.0001	blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	6	99708426	112483760	Rat
4145119	Mcs25	Mammary carcinoma susceptibility QTL 25		0.0001	mammary gland integrity trait (VT:0010552)	ratio of deaths to total study population during a period of time (CMO:0001023)	6	71278722	116278722	Rat
70176	Mcsm1	Mammary carcinoma susceptibility modifier QTL 1			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	64367996	109367996	Rat
10054138	Gmadr3	Adrenal mass QTL 3	3.68	0.00045	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	6	90871046	135871046	Rat
1581563	Uae33	Urinary albumin excretion QTL 33			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	93560258	136550638	Rat
1641917	Colcr5	Colorectal carcinoma resistance QTL 5	3.18	0.0009	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	6	98944780	143944780	Rat
61414	Pia3	Pristane induced arthritis QTL 3	4.5		joint integrity trait (VT:0010548)	post-insult time to onset of experimental arthritis (CMO:0001450)	6	100704576	136029228	Rat
724524	Uae2	Urinary albumin excretion QTL 2	2.7	0.0005	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	79198463	144254945	Rat
737827	Hcar11	Hepatocarcinoma resistance QTL 11	4.4		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	6	46050607	116278722	Rat
2303624	Vencon5	Ventilatory control QTL 5	4.45		respiration trait (VT:0001943)	minute ventilation (CMO:0000132)	6	93778632	138778632	Rat
1576309	Emca7	Estrogen-induced mammary cancer QTL 7	4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	20859430	113082285	Rat
2293837	Kiddil1	Kidney dilation QTL 1	3.7		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	86867923	110125012	Rat
2293842	Kiddil3	Kidney dilation QTL 3	4.3		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	86867923	110125012	Rat
10054123	Srcrt6	Stress Responsive Cort QTL 6	2.5	0.0043	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	90871046	135871046	Rat
724536	Uae7	Urinary albumin excretion QTL 7	3.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	93560258	136550638	Rat
1576302	Schws4	Schwannoma susceptibility QTL 4		0.0078	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	78204640	123204640	Rat
1581550	Pur8	Proteinuria QTL 8			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	93560258	136550638	Rat
1300075	Glom7	Glomerulus QTL 7	5.6	0.0000002	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	6	76937178	121937178	Rat
12801471	Schws9	Schwannoma susceptibility QTL 9			nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	101593607	146593607	Rat

Markers in Region

RH140792

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	102,792,686 - 102,792,927 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	106,598,200 - 106,598,440	NCBI	Rnor6.0
Rnor_5.0	6	114,736,322 - 114,736,562	UniSTS	Rnor5.0
RGSC_v3.4	6	106,987,770 - 106,988,010	UniSTS	RGSC3.4
Celera	6	100,625,182 - 100,625,422	UniSTS
RH 3.4 Map	6	732.5	UniSTS
Cytogenetic Map	6	q24	UniSTS

RH143195

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	102,792,822 - 102,793,075 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	106,598,336 - 106,598,588	NCBI	Rnor6.0
Rnor_5.0	6	114,736,458 - 114,736,710	UniSTS	Rnor5.0
RGSC_v3.4	6	106,987,906 - 106,988,158	UniSTS	RGSC3.4
Celera	6	100,625,318 - 100,625,570	UniSTS
RH 3.4 Map	6	738.0	UniSTS
Cytogenetic Map	6	q24	UniSTS

RH143409

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	6	108,423,622 - 108,423,874 (+)	Marker Load Pipeline
mRatBN7.2	6	102,692,460 - 102,692,712 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	106,499,816 - 106,500,067	NCBI	Rnor6.0
Rnor_5.0	6	114,639,079 - 114,639,330	UniSTS	Rnor5.0
RGSC_v3.4	6	106,876,517 - 106,876,768	UniSTS	RGSC3.4
Celera	6	100,526,473 - 100,526,724	UniSTS
RH 3.4 Map	6	738.0	UniSTS
Cytogenetic Map	6	q24	UniSTS

BF398997

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	102,773,210 - 102,773,402 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	106,578,724 - 106,578,915	NCBI	Rnor6.0
Rnor_5.0	6	114,716,846 - 114,717,037	UniSTS	Rnor5.0
RGSC_v3.4	6	106,968,294 - 106,968,485	UniSTS	RGSC3.4
Celera	6	100,605,596 - 100,605,787	UniSTS
RH 3.4 Map	6	738.0	UniSTS
Cytogenetic Map	6	q24	UniSTS

fc10a03.x1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	102,616,986 - 102,618,290 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	107,944,860 - 107,946,163	NCBI	Rnor6.0
Rnor_5.0	6	117,600,272 - 117,601,576	NCBI	Rnor5.0
RGSC_v3.4	6	106,800,999 - 106,802,302	UniSTS	RGSC3.4
Celera	6	100,451,085 - 100,452,388	UniSTS
Cytogenetic Map	6	q24	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
13	12	67	160	91	90	59	92	59	6	353	192	11	139	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_019342	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112783	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112784	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112785	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112787	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112789	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112790	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262367	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262368	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262369	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262370	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005505572	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U32436	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000058181 ⟹ ENSRNOP00000054984

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	107,995,999 - 108,524,602 (+)	Ensembl
mRatBN7.2 Ensembl	6	102,264,447 - 102,793,155 (+)	Ensembl
Rnor_6.0 Ensembl	6	106,497,125 - 106,598,668 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000086136 ⟹ ENSRNOP00000069089

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	107,996,208 - 108,527,480 (+)	Ensembl
mRatBN7.2 Ensembl	6	102,693,478 - 102,773,706 (+)	Ensembl
Rnor_6.0 Ensembl	6	106,496,992 - 106,602,139 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000095987 ⟹ ENSRNOP00000082201

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	107,996,208 - 108,555,840 (+)	Ensembl
mRatBN7.2 Ensembl	6	102,264,631 - 102,824,753 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000100420 ⟹ ENSRNOP00000077898

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	107,968,977 - 108,464,382 (+)	Ensembl
mRatBN7.2 Ensembl	6	102,264,447 - 102,733,221 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000103061 ⟹ ENSRNOP00000079796

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	107,968,977 - 108,504,465 (+)	Ensembl
mRatBN7.2 Ensembl	6	102,689,770 - 102,770,177 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000107970 ⟹ ENSRNOP00000091378

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	107,996,004 - 108,505,466 (+)	Ensembl
mRatBN7.2 Ensembl	6	102,264,447 - 102,773,304 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000109319 ⟹ ENSRNOP00000079945

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	107,996,626 - 108,527,480 (+)	Ensembl
mRatBN7.2 Ensembl	6	102,264,447 - 102,793,132 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000112595 ⟹ ENSRNOP00000092991

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	107,876,039 - 108,524,483 (+)	Ensembl
mRatBN7.2 Ensembl	6	102,264,447 - 102,793,132 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000113156 ⟹ ENSRNOP00000091512

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	107,876,039 - 108,524,483 (+)	Ensembl
mRatBN7.2 Ensembl	6	102,264,447 - 102,793,132 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000114544 ⟹ ENSRNOP00000085795

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	107,995,996 - 108,489,192 (+)	Ensembl
mRatBN7.2 Ensembl	6	102,264,447 - 102,824,753 (+)	Ensembl

RefSeq Acc Id:

NM_019342 ⟹ NP_062215

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	107,996,495 - 108,524,316 (+)	NCBI
mRatBN7.2	6	102,265,295 - 102,793,155 (+)	NCBI
Dahl_SR_JrHsd	6	109,248,226 - 109,776,683 (+)	NCBI
Lyon_Normotensive	6	108,657,734 - 109,186,199 (+)	NCBI
Lyon_Hypertensive	6	106,451,331 - 106,979,787 (+)	NCBI
F344_StmMcwi	6	105,603,650 - 106,132,124 (+)	NCBI
Rnor_6.0	6	106,310,442 - 106,598,668 (+)	NCBI
Rnor_5.0	6	114,636,387 - 114,736,790 (+)	NCBI
Celera	6	100,100,895 - 100,625,650 (+)	NCBI

Sequence:

show sequence

ATTTCAGATGCGTGACAGGTGCGGGTGTGTGTCTGCAGTTTGGGACTGTGCACGGCGAGCTTAC
TGTGGGAGAAGACACTCAGGATGGCTCAGGGATCCGGAGACCAGCGAGCAGTGGGGGTTGCTGA
TCCGGAAGAGAGTTCTCCCAACATGATTGTCTACTGCAAAATCGAGGACATCATTACGAAGATG
CAAGATGACAAGACAGGGGGTGTGCCCATCAGAACAGTTAAGAGCTTTCTCTCCAAAATCCCCA
GTGTCGTCACAGGTACTGACATTGTGCAGTGGCTTATGAAGAACCTTTCCATTGAAGACCCAGT
TGAAGCAATACACCTGGGAAGCCTTATCGCCGCCCAGGGCTACGTCTTCCCAATCTCAGACCAC
GTCCTCACCATGAAGGACGATGGCACCTTTTACCGTTTCCAGGCTCCTTACTTCTGGCCTTCAA
ACTGCTGGGAACCTGAAAACACAGACTATGCCATCTACCTCTGTAAGAGGACGATGCAGAACAA
GGCAAGGCTGGAATTGGCCGACTACGAAGCAGAAAACTTAGCGAGACTCCAGAGGGCCTTTGCA
AGGAAGTGGGAATTCATCTTTATGCAAGCAGAAGCGCAAGTCAAGATTGACCGGAAGAAAGATA
AGACGGAAAGGAAAATCTTGGATAGCCAAGAACGGGCCTTCTGGGATGTCCACAGGCCAGTGCC
AGGCTGTGTGAACACAACGGAAATGGATATCAGAAAATGTCGGCGTTTGAAGAATCCACAAAAG
GTTAAAAAGTCAGTATATGGTGTGACAGACGAGTCCCAGTCACAGAGTCCGGTGCACATACCAA
GCCAGCCAATCAGGAAAACTACAAAAGACGACATCCGAAAACAGATAACGTTTTTGAACGCACA
GATTGACAGACATTGTTTGAAAATGTCCAAAGTGGCTGAAAGCTTAATCGCTTACACGGAGCAG
TATGTGGAATACGACCCTTTCATAACACCAGCAGAGCCATCTAACCCTTGGATCAGCGATGACA
TCACCTTATGGGACATAGAGATGAGCAAAGAGCCCAGCCAGCAGCGAGTGAAGCGTTGGGGCTT
CTCTTTTGATGAGATACTGAAGGACCAGGTGGGGCGGGACCAGTTCCTCAGATTCCTGGAGTCA
GAATTCAGTTCAGAAAATCTCAGGTTCTGGCTGGCCGTCCAAGATCTCAAGAAGCAACCTCTAC
AGGATGTGGCCAAGAGGGTGGAGGAAATCTGGCAAGAGTTCCTAGCTCCCGGAGCCCCAAGTGC
AATCAACCTGGATTCTCACAGCTATGAGATAACCAGTCAGAATGTCAAAGATGGAGGGAGATAC
ACATTTGAAGATGCCCAGGAGCACATCTACAAGCTGATGAAGAGTGACAGCTACGCCCGCTTCC
TACGGTCCAATGCTTACCAGGATCTGTTGCTGGCCAAGAAGAAGGGAAAGTCGCTGGCGGGCAA
GCGCCTTACGGGCCTGATGCAGTCCTCCTGACCGCCCCGATCCCAGGCTCAGGGCCCGGGCCCA
CAGAGCACCCGGGCAGGCGACGCTCCACATCCAACGACAGAGCTTCCTTGCGGGGAGATTTGGT
CACTGTGAAGGAGAAAGAGTGAGGGCCATGGAGGGCACTGGTGGGAAGCTGCGGTGGGTGAATG
GGGAGACCAGAGAGAAAGAATCCACGGTGCTGGGCCAGCTGGGAGAGGCCCTGCTTATAGCCTC
TCTCTTGTACAGCCACACACCAATGCTCATTCTCAACAAGGGTCCATTTCTAACTGGGTCAGAG
AATGTCTCATGGGGTTCCTGTCTGACTATCTATCACTCAAGATGTTGTTGAACTCACCTGTCCA
GTCGTCTGGGGAATCCAGCAAACTTCAGAGGGACCCTGGGCACACAGTATTAAGCATCACCTCC
CTACCACTCTCTCTAAAGCATTGGCAGTGCTCACTGCCATCTGTTCCCCCTCCGCCACCCCACT
GGTATACCGGGTGGGTGACGGACGCTGCTTTCACACAAAATGTCACATCTTCAGTCCTAATGAC
CGTTCAAGTTCTCTCCACCCTCTGTGAGACCACATTTTAAATAAGTCTCCACGGGTGTGGTGGC
CAGCCCCAGTTCCCATCAAATGTCCAAAGGTCCTTGGCTTGAAGAGGCACCAGTACAGATAGTG
GAGTGTGTTGTTCAGCCACTGAAAGTTCGGGTGACAATCTTTTAAAAATATTACTACTTCCTGT
CTTCTGATTTTTGCCCCTTGCACCTTGACTTGTTCCCTTGTGTTTGGCTCGCAATAAACATGGC
CATGAACTCAGGGGCCATTAGGCTTCATCCCAA

hide sequence

RefSeq Acc Id:

XM_039112783 ⟹ XP_038968711

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	107,996,666 - 108,527,472 (+)	NCBI
mRatBN7.2	6	102,265,483 - 102,796,311 (+)	NCBI

RefSeq Acc Id:

XM_039112784 ⟹ XP_038968712

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	107,996,881 - 108,527,472 (+)	NCBI
mRatBN7.2	6	102,265,679 - 102,796,311 (+)	NCBI

RefSeq Acc Id:

XM_039112785 ⟹ XP_038968713

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	107,996,460 - 108,527,472 (+)	NCBI
mRatBN7.2	6	102,265,264 - 102,796,311 (+)	NCBI

RefSeq Acc Id:

XM_039112787 ⟹ XP_038968715

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	107,875,883 - 108,504,530 (+)	NCBI
mRatBN7.2	6	102,293,910 - 102,777,665 (+)	NCBI

RefSeq Acc Id:

XM_039112789 ⟹ XP_038968717

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	107,875,883 - 108,523,530 (+)	NCBI
mRatBN7.2	6	102,293,910 - 102,792,406 (+)	NCBI

RefSeq Acc Id:

XM_039112790 ⟹ XP_038968718

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	107,875,883 - 108,488,421 (+)	NCBI
mRatBN7.2	6	102,293,910 - 102,759,765 (+)	NCBI

RefSeq Acc Id:

XM_063262367 ⟹ XP_063118437

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	107,875,883 - 108,527,472 (+)	NCBI

RefSeq Acc Id:

XM_063262368 ⟹ XP_063118438

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	107,875,883 - 108,527,472 (+)	NCBI

RefSeq Acc Id:

XM_063262369 ⟹ XP_063118439

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	107,875,883 - 108,527,472 (+)	NCBI

RefSeq Acc Id:

XM_063262370 ⟹ XP_063118440

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	107,996,608 - 108,527,472 (+)	NCBI

RefSeq Acc Id:

XR_005505572

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	107,875,883 - 108,523,504 (+)	NCBI
mRatBN7.2	6	102,293,910 - 102,792,343 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_062215	(Get FASTA)	NCBI Sequence Viewer
	XP_038968711	(Get FASTA)	NCBI Sequence Viewer
	XP_038968712	(Get FASTA)	NCBI Sequence Viewer
	XP_038968713	(Get FASTA)	NCBI Sequence Viewer
	XP_038968715	(Get FASTA)	NCBI Sequence Viewer
	XP_038968717	(Get FASTA)	NCBI Sequence Viewer
	XP_038968718	(Get FASTA)	NCBI Sequence Viewer
	XP_063118437	(Get FASTA)	NCBI Sequence Viewer
	XP_063118438	(Get FASTA)	NCBI Sequence Viewer
	XP_063118439	(Get FASTA)	NCBI Sequence Viewer
	XP_063118440	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC52373	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000054984
	ENSRNOP00000069089
	ENSRNOP00000079945
	ENSRNOP00000085795
	ENSRNOP00000091378
	ENSRNOP00000091512
GenBank Protein	P49801	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_062215 ⟸ NM_019342

- UniProtKB:

F1LS67 (UniProtKB/TrEMBL), A0A8I6GJP9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAQGSGDQRAVGVADPEESSPNMIVYCKIEDIITKMQDDKTGGVPIRTVKSFLSKIPSVVTGTD
IVQWLMKNLSIEDPVEAIHLGSLIAAQGYVFPISDHVLTMKDDGTFYRFQAPYFWPSNCWEPEN
TDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKIL
DSQERAFWDVHRPVPGCVNTTEMDIRKCRRLKNPQKVKKSVYGVTDESQSQSPVHIPSQPIRKT
TKDDIRKQITFLNAQIDRHCLKMSKVAESLIAYTEQYVEYDPFITPAEPSNPWISDDITLWDIE
MSKEPSQQRVKRWGFSFDEILKDQVGRDQFLRFLESEFSSENLRFWLAVQDLKKQPLQDVAKRV
EEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGGRYTFEDAQEHIYKLMKSDSYARFLRSNAYQ
DLLLAKKKGKSLAGKRLTGLMQSS

hide sequence

Ensembl Acc Id:

ENSRNOP00000054984 ⟸ ENSRNOT00000058181

Ensembl Acc Id:

ENSRNOP00000069089 ⟸ ENSRNOT00000086136

RefSeq Acc Id:	XP_038968713 ⟸ XM_039112785
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6G3X7 (UniProtKB/TrEMBL), A0A8I6GJP9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038968711 ⟸ XM_039112783
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6G3X7 (UniProtKB/TrEMBL), A0A8I6GJP9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038968712 ⟸ XM_039112784
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6G3X7 (UniProtKB/TrEMBL), A0A8I6GJP9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038968717 ⟸ XM_039112789
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I6GJP9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038968715 ⟸ XM_039112787
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I6GJK3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038968718 ⟸ XM_039112790
- Peptide Label:	isoform X7
- UniProtKB:	A0A8I6GJP9 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000079796 ⟸ ENSRNOT00000103061

Ensembl Acc Id:

ENSRNOP00000079945 ⟸ ENSRNOT00000109319

Ensembl Acc Id:

ENSRNOP00000091512 ⟸ ENSRNOT00000113156

Ensembl Acc Id:

ENSRNOP00000092991 ⟸ ENSRNOT00000112595

Ensembl Acc Id:

ENSRNOP00000091378 ⟸ ENSRNOT00000107970

Ensembl Acc Id:

ENSRNOP00000085795 ⟸ ENSRNOT00000114544

Ensembl Acc Id:

ENSRNOP00000077898 ⟸ ENSRNOT00000100420

Ensembl Acc Id:

ENSRNOP00000082201 ⟸ ENSRNOT00000095987

RefSeq Acc Id:	XP_063118437 ⟸ XM_063262367
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6GJP9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063118438 ⟸ XM_063262368
- Peptide Label:	isoform X4
- UniProtKB:	A0A8I6GJP9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063118439 ⟸ XM_063262369
- Peptide Label:	isoform X5
- UniProtKB:	A0A8I6GJP9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063118440 ⟸ XM_063262370
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6G3X7 (UniProtKB/TrEMBL), A0A8I6GJP9 (UniProtKB/TrEMBL)

Protein Domains

DEP RGS

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P49801-F1-model_v2	AlphaFold	P49801	1-66	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:3569	AgrOrtholog
BioCyc Gene	G2FUF-36866	BioCyc
Ensembl Genes	ENSRNOG00000008082	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000058181	ENTREZGENE
	ENSRNOT00000086136	ENTREZGENE
	ENSRNOT00000107970	ENTREZGENE
	ENSRNOT00000109319	ENTREZGENE
	ENSRNOT00000113156	ENTREZGENE
	ENSRNOT00000114544	ENTREZGENE
Gene3D-CATH	1.10.167.10	UniProtKB/Swiss-Prot
InterPro	RGS	UniProtKB/Swiss-Prot
	RGS6/7/9/11	UniProtKB/Swiss-Prot
	RGS_sf	UniProtKB/Swiss-Prot
	RGS_subdomain_2	UniProtKB/Swiss-Prot
NCBI Gene	54295	ENTREZGENE
PANTHER	LP21163P	UniProtKB/Swiss-Prot
	REGULATOR OF G-PROTEIN SIGNALING 6	UniProtKB/Swiss-Prot
Pfam	RGS	UniProtKB/Swiss-Prot
PhenoGen	Rgs6	PhenoGen
PRINTS	RGSPROTEIN	UniProtKB/Swiss-Prot
PROSITE	RGS	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000008082	RatGTEx
Superfamily-SCOP	SSF48097	UniProtKB/Swiss-Prot
UniProt	A0A0G2JUG4_RAT	UniProtKB/TrEMBL
	A0A8I5YC31_RAT	UniProtKB/TrEMBL
	A0A8I5ZPB7_RAT	UniProtKB/TrEMBL
	A0A8I5ZTQ5_RAT	UniProtKB/TrEMBL
	A0A8I6A357_RAT	UniProtKB/TrEMBL
	A0A8I6AIT2_RAT	UniProtKB/TrEMBL
	A0A8I6G3X7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GJK3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GJP9	ENTREZGENE, UniProtKB/TrEMBL
	F1LS67	ENTREZGENE, UniProtKB/TrEMBL
	P49801	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2002-06-10	Rgs6	regulator of G-protein signaling 6			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_physical_interaction	human homolog binds neuronal growth associated protein SCG10	737642

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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RGD Manual Annotations