Rbbp9 (RB binding protein 9, serine hydrolase) - Rat Genome Database

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Gene: Rbbp9 (RB binding protein 9, serine hydrolase) Rattus norvegicus
Analyze
Symbol: Rbbp9
Name: RB binding protein 9, serine hydrolase
RGD ID: 3542
Description: Predicted to enable serine hydrolase activity. Involved in regulation of cell population proliferation. Orthologous to human RBBP9 (RB binding protein 9, serine hydrolase); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: B5T overexpressed gene protein; B5T-overexpressed gene protein; MGC124617; putative hydrolase RBBP9; RBBP-9; retinoblastoma binding protein 9; retinoblastoma-binding protein 9; serine hydrolase RBBP9
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83152,378,426 - 152,392,370 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3152,378,699 - 152,385,489 (-)EnsemblGRCr8
mRatBN7.23131,925,095 - 131,939,042 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3131,925,341 - 131,932,156 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3135,854,833 - 135,861,526 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03144,438,915 - 144,445,608 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03142,142,123 - 142,148,816 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03138,701,579 - 138,708,332 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3138,701,586 - 138,708,332 (-)Ensemblrn6Rnor6.0
Rnor_5.03145,131,493 - 145,138,246 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43133,091,157 - 133,097,910 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3130,819,354 - 130,826,133 (-)NCBICelera
RGSC_v3.13132,996,734 - 133,003,483 (-)NCBI
Cytogenetic Map3q41NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
amitrole  (EXP)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
diuron  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
epoxiconazole  (ISO)
fenvalerate  (EXP)
finasteride  (EXP)
gentamycin  (EXP)
ivermectin  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methapyrilene  (EXP)
methimazole  (EXP)
methylparaben  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-nitrosodiethylamine  (EXP)
nickel sulfate  (ISO)
nicotine  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (EXP,ISO)
pirinixic acid  (ISO)
pyrogallol  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
thiram  (ISO)
torcetrapib  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. A retinoblastoma-binding protein that affects cell-cycle control and confers transforming ability. Woitach JT, etal., Nat Genet 1998 Aug;19(4):371-4.
Additional References at PubMed
PMID:12477932   PMID:23376485  


Genomics

Comparative Map Data
Rbbp9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83152,378,426 - 152,392,370 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3152,378,699 - 152,385,489 (-)EnsemblGRCr8
mRatBN7.23131,925,095 - 131,939,042 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3131,925,341 - 131,932,156 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3135,854,833 - 135,861,526 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03144,438,915 - 144,445,608 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03142,142,123 - 142,148,816 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03138,701,579 - 138,708,332 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3138,701,586 - 138,708,332 (-)Ensemblrn6Rnor6.0
Rnor_5.03145,131,493 - 145,138,246 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43133,091,157 - 133,097,910 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3130,819,354 - 130,826,133 (-)NCBICelera
RGSC_v3.13132,996,734 - 133,003,483 (-)NCBI
Cytogenetic Map3q41NCBI
RBBP9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382018,486,540 - 18,497,225 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2018,486,540 - 18,497,234 (-)Ensemblhg38GRCh38
GRCh372018,467,184 - 18,477,869 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362018,415,184 - 18,425,887 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342018,415,189 - 18,425,887NCBI
Celera2018,541,234 - 18,551,942 (-)NCBICelera
Cytogenetic Map20p11.23NCBI
HuRef2018,429,215 - 18,439,909 (-)NCBIHuRef
CHM1_12018,467,190 - 18,477,891 (-)NCBICHM1_1
T2T-CHM13v2.02018,537,660 - 18,548,351 (-)NCBIT2T-CHM13v2.0
Rbbp9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392144,384,185 - 144,392,779 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2144,384,185 - 144,392,789 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm382144,542,265 - 144,550,859 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2144,542,265 - 144,550,869 (-)Ensemblmm10GRCm38
MGSCv372144,368,001 - 144,376,595 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362144,233,706 - 144,242,300 (-)NCBIMGSCv36mm8
MGSCv362145,595,875 - 145,604,246 (-)NCBIMGSCv36mm8
Celera2145,728,377 - 145,736,792 (-)NCBICelera
Cytogenetic Map2G1NCBI
cM Map271.02NCBI
Rbbp9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541527,033,658 - 27,044,558 (-)Ensembl
ChiLan1.0NW_00495541527,037,875 - 27,044,558 (-)NCBIChiLan1.0ChiLan1.0
RBBP9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22119,379,446 - 19,389,295 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12019,376,285 - 19,386,132 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02018,451,015 - 18,459,231 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12018,422,645 - 18,430,170 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2018,422,652 - 18,430,170 (-)EnsemblpanPan2panpan1.1
RBBP9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1244,704,957 - 4,712,644 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl244,704,362 - 4,710,798 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha244,635,528 - 4,643,633 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0245,112,474 - 5,120,576 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl245,112,440 - 5,120,570 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1244,712,327 - 4,720,421 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0244,816,933 - 4,825,030 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0245,095,537 - 5,103,633 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rbbp9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640153,355,664 - 153,366,992 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364851,787,028 - 1,798,277 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364851,787,048 - 1,796,233 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RBBP9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1726,736,526 - 26,760,242 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11726,740,559 - 26,749,698 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21730,230,145 - 30,239,276 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RBBP9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1247,549,090 - 47,559,459 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl247,552,024 - 47,559,365 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660782,282,476 - 2,292,825 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rbbp9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474119,214,536 - 19,222,530 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474119,214,436 - 19,222,511 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Rbbp9
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15124,188,119 - 124,194,352 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rbbp9
54 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:292
Count of miRNA genes:188
Interacting mature miRNAs:215
Transcripts:ENSRNOT00000010678
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3141555229186555229Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141555229186555229Rat
1582233Insul10Insulin level QTL 105.40.0015blood insulin amount (VT:0001560)serum insulin level times blood glucose level (CMO:0002040)3133259579178259579Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3141555229186555229Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3141555229186555229Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3151075912189428310Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)3129154923182114333Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3141555229186555229Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3141555229186555229Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3133134628178134628Rat
1300173Rf11Renal function QTL 113.38renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)3141508991166376254Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3152055202189428310Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)3112250810157250810Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3142898802187898802Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)3145335553189428310Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)3117537367162537367Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3125116475170116475Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3110225882155225882Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)3136091420155634702Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3139299381184299381Rat
5686842Rf59Renal function QTL 59urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)3122395989167395989Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3141508991177728348Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)3131036586176036586Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3137114333182114333Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)3131036586176036586Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)398651826167012663Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3151075912189428310Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3151075912189428310Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3110634702155634702Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3141555229186555229Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3144575244189428310Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)3116188400161188400Rat

Markers in Region
BF386174  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23131,930,904 - 131,931,056 (+)MAPPERmRatBN7.2
Rnor_6.03138,707,123 - 138,707,274NCBIRnor6.0
Rnor_5.03145,137,037 - 145,137,188UniSTSRnor5.0
RGSC_v3.43133,096,701 - 133,096,852UniSTSRGSC3.4
Celera3130,824,924 - 130,825,075UniSTS
RH 3.4 Map31181.2UniSTS
Cytogenetic Map3q41UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000010678   ⟹   ENSRNOP00000010678
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3152,378,699 - 152,385,489 (-)Ensembl
mRatBN7.2 Ensembl3131,925,341 - 131,932,156 (-)Ensembl
Rnor_6.0 Ensembl3138,701,586 - 138,708,332 (-)Ensembl
RefSeq Acc Id: NM_019219   ⟹   NP_062092
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83152,378,692 - 152,385,445 (-)NCBI
mRatBN7.23131,925,361 - 131,932,114 (-)NCBI
Rnor_6.03138,701,579 - 138,708,332 (-)NCBI
Rnor_5.03145,131,493 - 145,138,246 (-)NCBI
RGSC_v3.43133,091,157 - 133,097,910 (-)RGD
Celera3130,819,354 - 130,826,133 (-)RGD
Sequence:
RefSeq Acc Id: XM_039104444   ⟹   XP_038960372
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83152,378,426 - 152,392,370 (-)NCBI
mRatBN7.23131,925,095 - 131,939,042 (-)NCBI
RefSeq Acc Id: XM_039104445   ⟹   XP_038960373
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83152,378,426 - 152,385,480 (-)NCBI
mRatBN7.23131,925,095 - 131,932,146 (-)NCBI
RefSeq Acc Id: XM_063283215   ⟹   XP_063139285
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83152,378,426 - 152,392,320 (-)NCBI
RefSeq Acc Id: NP_062092   ⟸   NM_019219
- UniProtKB: Q3T1H7 (UniProtKB/Swiss-Prot),   O88350 (UniProtKB/Swiss-Prot),   A6K763 (UniProtKB/TrEMBL),   A0A8L2Q4I8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000010678   ⟸   ENSRNOT00000010678
RefSeq Acc Id: XP_038960372   ⟸   XM_039104444
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038960373   ⟸   XM_039104445
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063139285   ⟸   XM_063283215
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O88350-F1-model_v2 AlphaFold O88350 1-186 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692484
Promoter ID:EPDNEW_R3009
Type:initiation region
Name:Rbbp9_1
Description:RB binding protein 9, serine hydrolase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03138,708,356 - 138,708,416EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3542 AgrOrtholog
BioCyc Gene G2FUF-47597 BioCyc
Ensembl Genes ENSRNOG00000007972 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000010678 ENTREZGENE
Gene3D-CATH 3.40.50.1820 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7935765 IMAGE-MGC_LOAD
InterPro AB_hydrolase UniProtKB/Swiss-Prot
  Hydrolase_RBBP9/YdeN UniProtKB/Swiss-Prot
  RBBP9 UniProtKB/Swiss-Prot
KEGG Report rno:29459 UniProtKB/Swiss-Prot
MGC_CLONE MGC:124617 IMAGE-MGC_LOAD
NCBI Gene 29459 ENTREZGENE
PANTHER SERINE HYDROLASE RBBP9 UniProtKB/Swiss-Prot
  SERINE HYDROLASE RBBP9 UniProtKB/Swiss-Prot
Pfam Ser_hydrolase UniProtKB/Swiss-Prot
PhenoGen Rbbp9 PhenoGen
RatGTEx ENSRNOG00000007972 RatGTEx
Superfamily-SCOP SSF53474 UniProtKB/Swiss-Prot
UniProt A0A8L2Q4I8 ENTREZGENE, UniProtKB/TrEMBL
  A6K762_RAT UniProtKB/TrEMBL
  A6K763 ENTREZGENE, UniProtKB/TrEMBL
  O88350 ENTREZGENE
  Q3T1H7 ENTREZGENE
  RBBP9_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q3T1H7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-03 Rbbp9  RB binding protein 9, serine hydrolase  Rbbp9  retinoblastoma binding protein 9  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Rbbp9  retinoblastoma binding protein 9    retinoblastoma-binding protein 9  Name updated 1299863 APPROVED
2002-06-10 Rbbp9  retinoblastoma-binding protein 9      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_mutations_overexpression overexpression confers resistance to TGF-beta1 mediated growth inhibition in liver epithelial cells 69955
gene_physical_interaction binds retinoblastoma (Rb), can displace E2F from E2F-1 complexed with Rb in vitro 69955