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Gene: Mras (muscle RAS oncogene homolog) Rattus norvegicus

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Symbol:

Mras

Name:

muscle RAS oncogene homolog

RGD ID:

3111

Description:

Predicted to enable GTP-dependent protein binding activity; GTPase activity; and guanyl ribonucleotide binding activity. Predicted to be involved in Ras protein signal transduction. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in membrane. Predicted to be part of protein phosphatase type 1 complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in Noonan syndrome 11. Orthologous to human MRAS (muscle RAS oncogene homolog); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

muscle and microspikes RAS; ras-related protein M-Ras; ras-related protein R-Ras3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MRAS (muscle RAS oncogene homolog)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Mras (muscle and microspikes RAS)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Mras (muscle RAS oncogene homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MRAS (muscle RAS oncogene homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MRAS (muscle RAS oncogene homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Mras (muscle RAS oncogene homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MRAS (muscle RAS oncogene homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MRAS (muscle RAS oncogene homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Mras (muscle RAS oncogene homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Mras (muscle RAS oncogene homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Mras (muscle and microspikes RAS)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	MRAS (muscle RAS oncogene homolog)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	mras (muscle RAS oncogene homolog)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:ch73-116o1.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ras-2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	mras	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	mras	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	108,823,374 - 108,886,104 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	108,823,374 - 108,875,911 (-)	Ensembl				GRCr8
mRatBN7.2	8	99,944,036 - 100,006,771 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	99,944,036 - 99,996,408 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	105,610,343 - 105,663,748 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	103,809,642 - 103,863,053 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	101,652,159 - 101,705,561 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	107,629,028 - 107,656,851 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	107,629,028 - 107,681,512 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	107,054,728 - 107,082,497 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	104,244,660 - 104,272,556 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	99,345,811 - 99,373,539 (-)	NCBI		Celera
RGSC_v3.1	8	104,264,114 - 104,292,011 (-)	NCBI
Cytogenetic Map	8	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

carotid artery disease (ISO)

coronary artery disease (ISO)

Coronary Disease (ISO)

Desbuquois dysplasia (ISO)

genetic disease (ISO)

Noonan syndrome 11 (ISO)

RASopathy (ISO)

spermatogenic failure 57 (ISO)

type 2 diabetes mellitus (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

15-acetyldeoxynivalenol (ISO)

17alpha-ethynylestradiol (EXP,ISO)

17beta-estradiol (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-hydroxypropanoic acid (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

5-fluorouracil (ISO)

6-propyl-2-thiouracil (EXP)

8-Br-cAMP (ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

aldehydo-D-glucose (EXP)

amitrole (EXP)

ammonium chloride (EXP)

amphetamine (EXP)

Aroclor 1254 (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP)

Butylbenzyl phthalate (ISO)

C60 fullerene (EXP)

cadmium dichloride (ISO)

carbamazepine (ISO)

carbonyl sulfide (EXP)

chlorpyrifos (ISO)

cisplatin (ISO)

cocaine (EXP)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

D-glucose (EXP)

dibutyl phthalate (ISO)

diclofenac (ISO)

diethylstilbestrol (EXP,ISO)

Doramectin (EXP)

ethanol (ISO)

etoposide (ISO)

febuxostat (ISO)

fipronil (EXP)

furan (EXP)

glucose (EXP)

indole-3-methanol (EXP)

inulin (ISO)

ketamine (EXP)

ketoconazole (ISO)

leflunomide (ISO)

lithocholic acid (EXP)

manumycin A (EXP)

methoxychlor (EXP,ISO)

N-nitrosodiethylamine (ISO)

nickel atom (ISO)

orphenadrine (EXP)

ouabain (ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

progesterone (ISO)

propiconazole (EXP)

rac-lactic acid (ISO)

rotenone (EXP)

simvastatin (EXP)

sodium arsenate (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

sulindac sulfide (ISO)

tetrachloromethane (EXP)

thiram (ISO)

tipifarnib (EXP)

titanium dioxide (ISO)

torcetrapib (ISO)

urethane (ISO)

valproic acid (ISO)

vanadyl sulfate (ISO)

zinc atom (ISO)

zinc sulfate (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to leukemia inhibitory factor (ISO)

establishment or maintenance of cell polarity (IBA)

Ras protein signal transduction (IBA,ISO)

signal transduction (IEA)

Cellular Component

cytoplasm (ISO)

membrane (IEA)

plasma membrane (IBA,IEA)

protein phosphatase type 1 complex (ISO)

Molecular Function

G protein activity (IEA)

GTP binding (IEA)

GTP-dependent protein binding (ISO)

GTPase activity (IBA,IEA,ISO)

hydrolase activity (IEA)

nucleotide binding (IEA)

protein binding (IPI,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

mitogen activated protein kinase signaling pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Novel small GTPase M-Ras participates in reorganization of actin cytoskeleton.	Matsumoto K, etal., Oncogene 1997 Nov 13;15(20):2409-17.
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
6.	GOA pipeline	RGD automated data pipeline
7.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
9.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
10.	Regulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector.	Willard FS, etal., PLoS One. 2009;4(3):e4884. doi: 10.1371/journal.pone.0004884. Epub 2009 Mar 25.

Additional References at PubMed

PMID:10934204	PMID:12477932	PMID:16923128	PMID:19444311	PMID:20439489	PMID:23376485	PMID:28289718

Genomics

Comparative Map Data

Mras
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	108,823,374 - 108,886,104 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	108,823,374 - 108,875,911 (-)	Ensembl				GRCr8
mRatBN7.2	8	99,944,036 - 100,006,771 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	99,944,036 - 99,996,408 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	105,610,343 - 105,663,748 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	103,809,642 - 103,863,053 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	101,652,159 - 101,705,561 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	107,629,028 - 107,656,851 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	107,629,028 - 107,681,512 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	107,054,728 - 107,082,497 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	104,244,660 - 104,272,556 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	99,345,811 - 99,373,539 (-)	NCBI		Celera
RGSC_v3.1	8	104,264,114 - 104,292,011 (-)	NCBI
Cytogenetic Map	8	q31	NCBI

MRAS
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	138,347,648 - 138,405,535 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	138,347,648 - 138,405,534 (+)	Ensembl			hg38	GRCh38
GRCh37	3	138,066,490 - 138,124,377 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	139,549,315 - 139,607,067 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	3	139,574,404 - 139,607,073	NCBI
Celera	3	136,491,513 - 136,549,286 (+)	NCBI		Celera
Cytogenetic Map	3	q22.3	NCBI
HuRef	3	135,441,552 - 135,499,356 (+)	NCBI		HuRef
CHM1_1	3	138,030,261 - 138,088,159 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	141,088,198 - 141,146,101 (+)	NCBI		T2T-CHM13v2.0

Mras
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	99,267,473 - 99,319,505 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	99,267,473 - 99,319,434 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	9	99,385,420 - 99,437,700 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	99,385,420 - 99,437,381 (-)	Ensembl			mm10	GRCm38
MGSCv37	9	99,285,839 - 99,337,131 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	9	99,197,328 - 99,246,063 (-)	NCBI		MGSCv36	mm8
Celera	9	98,920,430 - 98,971,712 (-)	NCBI		Celera
Cytogenetic Map	9	E3.3	NCBI
cM Map	9	51.63	NCBI

Mras
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955501	615,303 - 670,782 (-)	Ensembl
ChiLan1.0	NW_004955501	615,303 - 670,404 (-)	NCBI	ChiLan1.0	ChiLan1.0

MRAS
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	136,253,974 - 136,311,964 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	136,258,713 - 136,316,693 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	135,377,488 - 135,435,338 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	142,827,020 - 142,884,582 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	142,827,020 - 142,884,582 (+)	Ensembl			panPan2	panpan1.1

MRAS
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	34,558,278 - 34,613,987 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	34,582,314 - 34,611,763 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	34,550,398 - 34,607,319 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	35,098,326 - 35,155,275 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	23	35,099,325 - 35,157,728 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	23	34,779,709 - 34,836,613 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	34,845,153 - 34,902,406 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	35,096,331 - 35,153,294 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Mras
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	73,933,041 - 73,985,346 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936540	672,544 - 725,143 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936540	672,783 - 725,129 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MRAS
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	79,139,764 - 79,211,135 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	79,137,489 - 79,211,139 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	86,781,175 - 86,826,924 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MRAS
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	52,137,409 - 52,195,247 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	52,135,727 - 52,170,020 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666041	25,149,689 - 25,208,288 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mras
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	14,879,484 - 14,940,255 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624730	14,879,631 - 14,938,683 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Mras
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	8	90,726,227 - 90,778,971 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Mras
295 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	962
Count of miRNA genes:	331
Interacting mature miRNAs:	443
Transcripts:	ENSRNOT00000050374
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303171	Bp331	Blood pressure QTL 331	5.57	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	105462581	132782436	Rat
1300177	Cm2	Cardiac mass QTL 2	3.65		heart mass (VT:0007028)	heart weight (CMO:0000017)	8	63141536	109261840	Rat
1549909	Stresp11	Stress response QTL 11	6.83	0.0019	stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	8	82352698	127352698	Rat
631210	Bw3	Body weight QTL3	5.9		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	8	61019838	121662124	Rat
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	49849908	118871671	Rat
9590292	Uminl3	Urine mineral level QTL 3	3.62	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	8	80768445	125768445	Rat
8694446	Bw170	Body weight QTL 170	12.07	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	8	80768445	125768445	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	70041301	121080908	Rat
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	68690349	119799881	Rat
10450865	Bw175	Body weight QTL 175	4.1		total fat pad mass (VT:0015008)	adipose tissue molecular composition measurement (CMO:0000484)	8	84192326	129192326	Rat
724539	Cm19	Cardiac mass QTL 19	2.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	8	103375781	129871912	Rat
738011	Anxrr9	Anxiety related response QTL 9	6.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	8	102413464	132782436	Rat
71120	Niddm21	Non-insulin dependent diabetes mellitus QTL 21	3.73		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	8	66992095	111992095	Rat
8693654	Alc32	Alcohol consumption QTL 32	2	0.755	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	8	97492344	116428905	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	55428333	127966348	Rat
634332	Pia18	Pristane induced arthritis QTL 18	4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	84192326	132782436	Rat
2316950	Scl66	Serum cholesterol level QTL 66	4.1		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	39106363	114525825	Rat
2300181	Bmd55	Bone mineral density QTL 55	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	85348065	130348065	Rat
1300171	Bp184	Blood pressure QTL 184	3.66		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	8	79394435	132782436	Rat
2313400	Anxrr25	Anxiety related response QTL 25			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	8	98145073	122898010	Rat
8694200	Abfw4	Abdominal fat weight QTL 4	9.07	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	8	80768445	125768445	Rat
8694392	Bw161	Body weight QTL 161	8.06	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	8	80768445	125768445	Rat
61437	Cia6	Collagen induced arthritis QTL 6			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	91340911	131690273	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001388501	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_012981	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039080883	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039080884	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039080887	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063264949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC141164	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC085752	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D89863	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000050374 ⟹ ENSRNOP00000045851

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	108,823,374 - 108,869,968 (-)	Ensembl
mRatBN7.2 Ensembl	8	99,944,036 - 99,978,327 (-)	Ensembl
Rnor_6.0 Ensembl	8	107,629,028 - 107,656,861 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000077963 ⟹ ENSRNOP00000072543

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	99,946,502 - 99,996,408 (-)	Ensembl
Rnor_6.0 Ensembl	8	107,631,488 - 107,681,512 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000118697 ⟹ ENSRNOP00000085134

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	108,823,374 - 108,875,911 (-)	Ensembl
mRatBN7.2 Ensembl	8	99,944,036 - 99,973,929 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000157189 ⟹ ENSRNOP00000099587

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	108,823,374 - 108,858,008 (-)	Ensembl

RefSeq Acc Id:

NM_001388501 ⟹ NP_001375430

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	108,823,374 - 108,876,147 (-)	NCBI
mRatBN7.2	8	99,944,036 - 99,996,814 (-)	NCBI

RefSeq Acc Id:

NM_012981 ⟹ NP_037113

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	108,823,374 - 108,875,911 (-)	NCBI
mRatBN7.2	8	99,944,036 - 99,996,578 (-)	NCBI
Rnor_6.0	8	107,629,028 - 107,656,851 (-)	NCBI
Rnor_5.0	8	107,054,728 - 107,082,497 (-)	NCBI
RGSC_v3.4	8	104,244,660 - 104,272,556 (-)	RGD
Celera	8	99,345,811 - 99,373,539 (-)	RGD

Sequence:

show sequence

GTCATCCTGGGGTCTGACTACCAGAAGCATGGCGACCAGCGCTGTTCCCAGTGACAACCTTCCC
ACATATAAACTGGTAGTGGTGGGAGATGGCGGTGTGGGCAAGAGTGCTCTCACTATTCAGTTTT
TCCAGAAGATCTTCGTGCCTGACTACGACCCCACCATTGAAGACTCCTACCTGAAGCATACAGA
GATCGACAATCAATGGGCCATCTTGGACGTTCTGGACACAGCTGGGCAGGAGGAGTTCAGTGCC
ATGCGGGAGCAATACATGCGCACAGGGGATGGCTTCCTCATTGTCTACTCTGTCACCGACAAGG
CCAGCTTCGAGCACGTGGACCGCTTCCACCAGCTCATTCTGCGTGTCAAGGACAGGGAGTCATT
CCCAATGATCCTCGTGGCCAACAAAGTGGACCTGATGCACCTAAGGAAAATCACCAGGGACCAA
GGAAAAGAAATGGCGACCAAATACAATATCCCATATATAGAAACCAGTGCCAAGGACCCGCCTC
TCAACGTGGACAAAACCTTCCATGACCTAGTTAGAGTAATTAGGCAACAGGTTCCAGAGAAAAA
CCAGAAGAAGAAAAAGAAGACAAAATGGCGAGGGGACAGGGCCACCGGCACTCACAAACTACAG
TGTGTCATCTTGTGACAGCCTGAAGCCCTGGGCATAGCAACCGTGAACTGCCAGCCCTGGGACC
AGCCCACTGCCTAACTGCACTGAGAACCATTTCTAACCACAGCCCTTGGCTCTGGACTGGGCAC
AGGAAGAGAACGAGGGAGGAGGGGCAGGAGCAGGCAGGGGCTGGCTTTGCTGCTTCTCCCATGG
AGACATGGAGACAGCTTCCAAACCCTTGTTGTTGATTGAGCCCAGTTCCCAGTCTCTTGGTGGG
CTTGTTGTTTCTTTTAACTCCATAGGGCTGGTTTGCTGTGGAAGTGCTTTTATCCACATTCAAC
GCACCAGACAAGCCATGAGCAAGCTTCCTCCCTGACCCCGTCCCCAGTGTCTGAGCTCTTGTGT
CTTTTGTAGATTTTTAAATTATTTGAGTAATGATTATTTTATTAAAGAGGTCTGTGCCCATTGC
CTGGCAAAGCCCCAAGTCTTTGGCAGACCTCCGATAAATGTCTGGAACAGGGCTGTTGTCTTCT
TAACTGAGTGTTCCTAGCAGTGCCAAACTCCATGGATGGATGAAAGACGGCCGGCCGAATCGAG
TGGATTCTTATCAGAAGCCTGGAGTCAAACCCAGGAAGCAAACAGACCCCAGAGACTGGGGTGG
ATTTACCTTGAGGGCTTTGGTGTGGTTGAAAATGTCAGAGATTAGAAAATAAAACCCCCTCGCC
AATACATCCCCATCCCCGCCCACACTGAAGTGAGAGCCAGCTGGACCCGCTTCACCCCTGGAGG
GGATTCTCTCTCCCTGAGTGTGGAGAGGCCACTGACTGGTTTTGCACAAGTACTCATTTGCTTT
CCTGCTTTCTGGGCAGTGGATAAATTCTGTGTTCAGATGTGGACAGGACCTTGGGCTTCTCGAA
AGTGTCCCTGTTTGCTCTCAGACTGTGTGTTGCCGTGCCTCTGACACAAACATAGGGACATGTT
CAAGGAGTCGAAGGTGACAGCTCTGAACCGAAGGCACTGCTGTCTGGGAAGCCCCAGGACTGAA
GCCATCTCCACCTGGGTCAGCTGACCATCACCGTTATTGGTCCGGCCAATGAGCAAGCGCCTTC
TAGCACGAGTGGTATGGCTGCCTTTTGGGACACACTTCCTTTGCTCTCTGGTCAAAGTGGAAGA
AAAGCTGAGCCGGTGGCATGGCCCACACACTTATTTCAGCAGGGACACCTCCCGCCATGATGCA
CCCCTCCCTCTCTGGTGCTGCTAGTGGGGTAGAGATTGCCTTTTCCCAGCTAAGATTCCCCACG
GAGGAACAGCAAGAACAAAGTACACCCTGTGAGGGGGTCAGAAGCGGAGGTGGCAGCATAGTTA
GTGACCTGTCAGCTCACCTTGCAAAACTGAGGCTCCCCTCAGAGGCTGGGCCAATGTGGAGAAA
GAAACAGGTGGAAGGAAGTCCAAGGAAATCAGGCACCGAATGGATGTCCAGCCTCGTGATTCTT
TTTCAACCCAGAAAGTCCTAAGTTGTTCAAACACAGGGTCATCAGGACAGAAGGCCCCCATTCA
AGGGAAAATTCTGCTGCAGAAGGAGATGACCCAACGCTTGTGCCAGCTAGAGATCAAAATTCCT
ACTTACCAAACTGCCACCCACCCCGATTTTTATTTCTATTCCTTAAAAGGATGCCAGATGAGGT
ATCACACCATTTCTCGGATCCTGTAATCCTTACGATTATTTTCAACACTAAAAGGACCAGGCTT
GCTCCAGCCTCGGGCCACAGTAGCTGCAGCCTGGAGAGAGGACAGTTGGAAGAAAGGTCAGGAT
AGTCCACACTCAGGGCAGCAGCCACTGCCAGAGAAGCCATGTCCTGCCTGCCACCTGCTCCCGG
CACACCCCTGCTTCTGTGGACCAGCACCTCCACTGTGCAGAGTGGGGACTCTCCCCGGAAGCAG
AACAGCTGCCTAGACCAAAGCCCCCAAGTCACACAGATAACCAGAAGGGAGGCTCCCAGCACCC
CCGGCCCTCTCCGAGGCAGCAGTGCATTCAGACCCATCATCCAGGGCATCCATTCCAAACTGCC
CACGTCCTAAACTGACTGCACATGCGGATGGACAAACCGGCTGGCATCCCGCCTTCTGCAGTCT
CTAGAGCAGGGCTTTCATCTCCCACAATCCCGCCCCCTCCCCGTGTATGACACGCATAGCTGAC
ACATCAGAATTAGAAATGAGCCCTCTGACAGAGTTTCCAGGGAGGCAGAGTATGCCTAGTGAGT
CCCCATCACCAGCTGACAGGGGACATCGGGAAACTGTTGGCCGTGACACCACAGGACCGAGGAT
CCTTTGGGTCTGTATTGAGCTGTCATTCCGAGGTCCCCTCTAGCCAGAAACCTGTGTTCCCATC
ACATCCGATGCACCCCTGCGATCCCCTCACCCCTGGCTTCTATTGTGTGCTGATTTTCTTCCAT
TACTCTGCCATTTCTTCATAGGTTCGTTTCTCCCCCTAGCCATCCCCTCTCCCCCAGTATAGGG
CTATGCTGTGACCCCCTCCTTCTCAAGCACCTTGCCACACGGGGAACATCTGGATGTTTCCTTT
AGGACTTCCCCATCTCCCCATGACTCTCGACGTGGAGTACCTGATTGGATTAGTGCGGCCTGTC
TTGCCTCCCAGGAGAGATGACCCACTGACCATGTCAGCTCTAATCCCAAAGCCCCTCAGACCCA
CCACACTAAGTCCAGAGCCACAGAGGGGTCTCTTCTTTTAGCAGCCCACCTGGTTGGAGACTCC
ACATTGGGTCAGGTTTACCCAGAATGCCAGATACTTGAAACACTGAGCCCTTTGTGTGACAGTA
TTAGCAGGTGGCCGTTGTCATGCGGCAAGCAAGAATGATGATGCCTGGATATCTTGTTGATGCT
TGAGCCTTTTATGTACTTTTTATCAAGTCTTTGTGTATCTCTACTTATTAATAAACAAACAGAG
TTCCTGTCTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039080883 ⟹ XP_038936811

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	108,823,377 - 108,857,628 (-)	NCBI
mRatBN7.2	8	99,944,039 - 99,978,326 (-)	NCBI

RefSeq Acc Id:

XM_039080884 ⟹ XP_038936812

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	108,823,377 - 108,875,859 (-)	NCBI
mRatBN7.2	8	99,944,039 - 99,996,526 (-)	NCBI

RefSeq Acc Id:

XM_039080887 ⟹ XP_038936815

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	108,823,377 - 108,886,104 (-)	NCBI
mRatBN7.2	8	99,944,039 - 100,006,771 (-)	NCBI

RefSeq Acc Id:

XM_063264949 ⟹ XP_063121019

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	108,823,377 - 108,875,859 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001375430	(Get FASTA)	NCBI Sequence Viewer
	NP_037113	(Get FASTA)	NCBI Sequence Viewer
	XP_038936811	(Get FASTA)	NCBI Sequence Viewer
	XP_038936812	(Get FASTA)	NCBI Sequence Viewer
	XP_038936815	(Get FASTA)	NCBI Sequence Viewer
	XP_063121019	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH85752	(Get FASTA)	NCBI Sequence Viewer
	BAA20531	(Get FASTA)	NCBI Sequence Viewer
	EDL77441	(Get FASTA)	NCBI Sequence Viewer
	EDL77442	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000045851
	ENSRNOP00000085134
GenBank Protein	P97538	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_037113 ⟸ NM_012981
- UniProtKB:	P97538 (UniProtKB/Swiss-Prot), O09021 (UniProtKB/Swiss-Prot), Q5RKJ7 (UniProtKB/TrEMBL), A6I2D6 (UniProtKB/TrEMBL), A0A0G2K389 (UniProtKB/TrEMBL)
- Sequence:	show sequence MATSAVPSDNLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILD VLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKV DLMHLRKITRDQGKEMATKYNIPYIETSAKDPPLNVDKTFHDLVRVIRQQVPEKNQKKKKKTKW RGDRATGTHKLQCVIL hide sequence

Ensembl Acc Id:

ENSRNOP00000072543 ⟸ ENSRNOT00000077963

Ensembl Acc Id:

ENSRNOP00000045851 ⟸ ENSRNOT00000050374

RefSeq Acc Id:	NP_001375430 ⟸ NM_001388501
- UniProtKB:	P97538 (UniProtKB/Swiss-Prot), O09021 (UniProtKB/Swiss-Prot), Q5RKJ7 (UniProtKB/TrEMBL), A6I2D6 (UniProtKB/TrEMBL), A0A0G2K389 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038936815 ⟸ XM_039080887
- Peptide Label:	isoform X2
- UniProtKB:	P97538 (UniProtKB/Swiss-Prot), O09021 (UniProtKB/Swiss-Prot), Q5RKJ7 (UniProtKB/TrEMBL), A6I2D6 (UniProtKB/TrEMBL), A0A0G2K389 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038936812 ⟸ XM_039080884
- Peptide Label:	isoform X2
- UniProtKB:	P97538 (UniProtKB/Swiss-Prot), O09021 (UniProtKB/Swiss-Prot), Q5RKJ7 (UniProtKB/TrEMBL), A6I2D6 (UniProtKB/TrEMBL), A0A0G2K389 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038936811 ⟸ XM_039080883
- Peptide Label:	isoform X1
- UniProtKB:	F7FMZ0 (UniProtKB/TrEMBL), A0A8I6A109 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000085134 ⟸ ENSRNOT00000118697

RefSeq Acc Id:	XP_063121019 ⟸ XM_063264949
- Peptide Label:	isoform X2
- UniProtKB:	P97538 (UniProtKB/Swiss-Prot), O09021 (UniProtKB/Swiss-Prot), A0A0G2K389 (UniProtKB/TrEMBL), A6I2D6 (UniProtKB/TrEMBL), Q5RKJ7 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000099587 ⟸ ENSRNOT00000157189

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P97538-F1-model_v2	AlphaFold	P97538	1-208	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:3111	AgrOrtholog
BioCyc Gene	G2FUF-29396	BioCyc
Ensembl Genes	ENSRNOG00000014060	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000050374	ENTREZGENE
	ENSRNOT00000118697	ENTREZGENE
Gene3D-CATH	3.40.50.300	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7130510	IMAGE-MGC_LOAD
InterPro	P-loop_NTPase	UniProtKB/Swiss-Prot
	Small_GTP-bd_dom	UniProtKB/Swiss-Prot
	Small_GTPase	UniProtKB/Swiss-Prot
	Small_GTPase_Ras-type	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93575	IMAGE-MGC_LOAD
NCBI Gene	25482	ENTREZGENE
PANTHER	PTHR24070	UniProtKB/Swiss-Prot
Pfam	Ras	UniProtKB/Swiss-Prot
PhenoGen	Mras	PhenoGen
PRINTS	RASTRNSFRMNG	UniProtKB/Swiss-Prot
PROSITE	RAS	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000014060	RatGTEx
SMART	RAB	UniProtKB/Swiss-Prot
	RAN	UniProtKB/Swiss-Prot
	RAS	UniProtKB/Swiss-Prot
	RHO	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF52540	UniProtKB/Swiss-Prot
TIGR	TC206441
UniProt	A0A0G2K389	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A109	ENTREZGENE
	A0ABK0L9P9_RAT	UniProtKB/TrEMBL
	A6I2D6	ENTREZGENE, UniProtKB/TrEMBL
	F7FMZ0	ENTREZGENE, UniProtKB/TrEMBL
	O09021	ENTREZGENE
	P97538	ENTREZGENE
	Q5RKJ7	ENTREZGENE
	RASM_RAT	UniProtKB/Swiss-Prot
UniProt Secondary	O09021	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-11-11	Mras	muscle RAS oncogene homolog	Mras	muscle and microspikes RAS	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-06-10	Mras	Muscle and microspikes RAS			Symbol and Name status set to approved	70586	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_function	has GTP-binding and GTPase activities	729080

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)