Matr3 (matrin 3) - Rat Genome Database

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Pathways
Gene: Matr3 (matrin 3) Rattus norvegicus
Analyze
Symbol: Matr3
Name: matrin 3
RGD ID: 3052
Description: Predicted to enable identical protein binding activity and miRNA binding activity. Predicted to be involved in activation of innate immune response and post-transcriptional regulation of gene expression. Predicted to act upstream of or within blastocyst formation; heart valve development; and ventricular septum development. Located in nuclear matrix. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 21. Orthologous to human MATR3 (matrin 3); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: matrin-3; nuclear scaffold protein P130/MAT3; P130/MAT3; snhg4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Matr3-ps1   Matr3-ps3  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81827,428,190 - 27,474,421 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1827,432,179 - 27,470,421 (+)EnsemblGRCr8
mRatBN7.21827,154,098 - 27,193,212 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1827,163,714 - 27,193,166 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1827,291,153 - 27,320,586 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01828,053,486 - 28,082,679 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01827,388,370 - 27,417,564 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01828,351,691 - 28,390,764 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1828,361,283 - 28,390,717 (+)Ensemblrn6Rnor6.0
Rnor_5.01828,074,345 - 28,103,874 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41828,171,639 - 28,215,659 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1826,897,382 - 26,926,742 (+)NCBICelera
RGSC_v3.11828,221,884 - 28,242,302 (+)NCBI
Cytogenetic Map18p11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,6-dimethoxyphenol  (ISO)
2,6-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
3',5'-cyclic UMP  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acrolein  (ISO)
actinomycin D  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
Aroclor 1254  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumarin  (ISO)
DDT  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
enzyme inhibitor  (ISO)
ethyl methanesulfonate  (ISO)
flavonoids  (EXP)
FR900359  (ISO)
fulvestrant  (ISO)
furfural  (ISO)
gallic acid  (ISO)
geldanamycin  (ISO)
genistein  (ISO)
gentamycin  (EXP)
irinotecan  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
Nutlin-3  (ISO)
ozone  (ISO)
paracetamol  (EXP)
PCB138  (EXP)
pentachlorophenol  (ISO)
phenethyl isothiocyanate  (EXP)
phenobarbital  (ISO)
PhIP  (EXP)
raloxifene  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
succimer  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
tolcapone  (EXP)
Tributyltin oxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nuclear matrix  (IDA,IEA)
nucleus  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Molecular cloning of matrin 3. A 125-kilodalton protein of the nuclear matrix contains an extensive acidic domain. Belgrader P, etal., J Biol Chem 1991 May 25;266(15):9893-9.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Molecular properties and intracellular localization of rat liver nuclear scaffold protein P130. Hibino Y, etal., Biochim Biophys Acta. 2006 May;1759(5):195-207. Epub 2006 May 22.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
12. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:1575753   PMID:8250943   PMID:8357833   PMID:9111204   PMID:9524232   PMID:10860485   PMID:11112453   PMID:16396499   PMID:16641100   PMID:19946888   PMID:21771347   PMID:22082260  
PMID:22658674   PMID:22681889   PMID:22871113   PMID:24625528   PMID:25416956   PMID:25574029   PMID:27869233   PMID:28431233   PMID:28712728   PMID:28755400   PMID:29476059   PMID:30597036  
PMID:35736640  


Genomics

Comparative Map Data
Matr3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81827,428,190 - 27,474,421 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1827,432,179 - 27,470,421 (+)EnsemblGRCr8
mRatBN7.21827,154,098 - 27,193,212 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1827,163,714 - 27,193,166 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1827,291,153 - 27,320,586 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01828,053,486 - 28,082,679 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01827,388,370 - 27,417,564 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01828,351,691 - 28,390,764 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1828,361,283 - 28,390,717 (+)Ensemblrn6Rnor6.0
Rnor_5.01828,074,345 - 28,103,874 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41828,171,639 - 28,215,659 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1826,897,382 - 26,926,742 (+)NCBICelera
RGSC_v3.11828,221,884 - 28,242,302 (+)NCBI
Cytogenetic Map18p11NCBI
MATR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385139,274,101 - 139,331,677 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5139,273,752 - 139,331,677 (+)Ensemblhg38GRCh38
GRCh375138,609,790 - 138,667,366 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365138,637,691 - 138,694,029 (+)NCBIBuild 36Build 36hg18NCBI36
Build 345138,657,253 - 138,694,023NCBI
Celera5134,731,161 - 134,789,067 (+)NCBICelera
Cytogenetic Map5q31.2NCBI
HuRef5133,798,796 - 133,857,165 (+)NCBIHuRef
CHM1_15138,042,040 - 138,099,954 (+)NCBICHM1_1
T2T-CHM13v2.05139,800,176 - 139,857,743 (+)NCBIT2T-CHM13v2.0
Matr3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391835,686,462 - 35,724,526 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1835,695,191 - 35,726,888 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381835,562,158 - 35,592,045 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1835,562,138 - 35,593,835 (+)Ensemblmm10GRCm38
MGSCv371835,721,812 - 35,751,699 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361835,688,242 - 35,717,383 (+)NCBIMGSCv36mm8
Celera1836,018,404 - 36,048,039 (+)NCBICelera
Cytogenetic Map18B2NCBI
cM Map1819.14NCBI
Matr3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554181,213,503 - 1,269,746 (-)Ensembl
ChiLan1.0NW_0049554181,213,503 - 1,269,755 (-)NCBIChiLan1.0ChiLan1.0
MATR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24134,560,617 - 134,598,387 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15132,700,169 - 132,737,940 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05134,664,893 - 134,702,566 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15140,788,667 - 140,825,064 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5140,788,709 - 140,825,064 (+)EnsemblpanPan2panpan1.1
MATR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11126,736,728 - 26,790,449 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1126,758,261 - 26,790,449 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1125,527,245 - 25,559,143 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01127,616,211 - 27,648,180 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1127,594,256 - 27,648,043 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11126,323,723 - 26,355,841 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01126,145,651 - 26,177,531 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01126,810,878 - 26,842,761 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Matr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213153,192,756 - 153,239,429 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365318,385,743 - 8,420,836 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365318,385,919 - 8,418,753 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MATR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2141,179,566 - 141,231,015 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.12141,179,515 - 141,230,259 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22147,010,375 - 147,060,861 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MATR3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12341,955,451 - 41,992,280 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2341,969,459 - 41,994,233 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603435,898,083 - 35,935,039 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Matr3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474332,115,544 - 32,146,921 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474332,086,821 - 32,147,079 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Matr3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1158,777,040 - 8,805,189 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Matr3
149 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:107
Count of miRNA genes:88
Interacting mature miRNAs:97
Transcripts:ENSRNOT00000026949
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182507112683910656Rat
2301409Cm70Cardiac mass QTL 700.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)18706572852065728Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)182201556261600538Rat
1331735Rf44Renal function QTL 442.981urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)181564228031610627Rat
61382Bp46Blood pressure QTL 4618.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181221668431644508Rat
2301413Bp318Blood pressure QTL 3180.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182682218671822186Rat
12904716Am21Aortic mass QTL 210.005aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)18706572852065728Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182349405785487725Rat
12904714Cm131Cardiac mass QTL 1310.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)18706572852065728Rat
12904715Cm132Cardiac mass QTL 1320.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)18706572852065728Rat
6903345Bp349Blood pressure QTL 3493.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18391722648917226Rat
12904668Bw188Body weight QTL 1880.03body mass (VT:0001259)body weight (CMO:0000012)182682218671822186Rat
2313082Bss85Bone structure and strength QTL 850.80.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)181522610142690662Rat
12904669Cm125Cardiac mass QTL 1250.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)182682218671822186Rat
6903347Bp350Blood pressure QTL 3504.4arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18131610627Rat
12904670Cm126Cardiac mass QTL 1260.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)182682218671822186Rat
2312568Glom21Glomerulus QTL 2120.005kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)18546045542690191Rat
6903349Bp351Blood pressure QTL 3513.5arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18391722648917226Rat
631509Sald2Serum aldosterone level QTL 22.9blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)182641582171415821Rat
6903351Bp352Blood pressure QTL 3523.3arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18391722648917226Rat
12904677Kidm72Kidney mass QTL 720.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)182682218671822186Rat
1331766Bp236Blood pressure QTL 2363.022arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18131610627Rat
12904673Cm127Cardiac mass QTL 1270.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)182682218671822186Rat
12904675Am19Aortic mass QTL 190.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)182682218671822186Rat
631264Scl22Serum cholesterol level QTL 226.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)181221668431644508Rat
1331775Bp235Blood pressure QTL 2353.201arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181564228031610627Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)18144930869Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181955353285493247Rat
2293708Bss46Bone structure and strength QTL 468.80.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)181206648257066482Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181206648285493247Rat
2312598Bp340Blood pressure QTL 3400.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18381190230809809Rat
2300180Bmd67Bone mineral density QTL 674.80.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)18134566578Rat
2299160Iddm35Insulin dependent diabetes mellitus QTL 352.79blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)18448264849482648Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18154490981Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181206648285493247Rat
11565454Kidm59Kidney mass QTL 590.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)18706572852065728Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181564228086134022Rat
2293661Bss50Bone structure and strength QTL 504.640.0003lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)18134566578Rat
61375Bp41Blood pressure QTL 412.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)18430735449307354Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_019149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB205483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC135285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC062231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC168723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC420149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M63485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000026949   ⟹   ENSRNOP00000026949
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1827,432,179 - 27,467,237 (+)Ensembl
mRatBN7.2 Ensembl1827,163,714 - 27,193,166 (+)Ensembl
Rnor_6.0 Ensembl1828,361,283 - 28,390,696 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000083993   ⟹   ENSRNOP00000073436
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1828,370,085 - 28,390,717 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000141241   ⟹   ENSRNOP00000100340
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1827,432,179 - 27,467,237 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000146659   ⟹   ENSRNOP00000103016
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1827,437,809 - 27,467,421 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000147139   ⟹   ENSRNOP00000110855
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1827,432,179 - 27,470,421 (+)Ensembl
RefSeq Acc Id: NM_019149   ⟹   NP_062022
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,437,824 - 27,467,257 (+)NCBI
mRatBN7.21827,163,729 - 27,193,164 (+)NCBI
Rnor_6.01828,361,283 - 28,390,716 (+)NCBI
Rnor_5.01828,074,345 - 28,103,874 (+)NCBI
RGSC_v3.41828,171,639 - 28,215,659 (+)RGD
Celera1826,897,382 - 26,926,742 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006254534   ⟹   XP_006254596
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,437,730 - 27,467,258 (+)NCBI
mRatBN7.21827,163,644 - 27,193,212 (+)NCBI
Rnor_6.01828,361,227 - 28,390,764 (+)NCBI
Rnor_5.01828,074,345 - 28,103,874 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600886   ⟹   XP_017456375
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,428,190 - 27,467,258 (+)NCBI
mRatBN7.21827,154,098 - 27,193,212 (+)NCBI
Rnor_6.01828,351,691 - 28,390,764 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600887   ⟹   XP_017456376
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,437,959 - 27,467,258 (+)NCBI
mRatBN7.21827,163,891 - 27,193,212 (+)NCBI
Rnor_6.01828,361,365 - 28,390,764 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063277175   ⟹   XP_063133245
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,437,730 - 27,474,421 (+)NCBI
RefSeq Acc Id: XM_063277176   ⟹   XP_063133246
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,437,837 - 27,474,421 (+)NCBI
RefSeq Acc Id: XM_063277177   ⟹   XP_063133247
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,438,185 - 27,474,421 (+)NCBI
RefSeq Acc Id: XM_063277178   ⟹   XP_063133248
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,437,899 - 27,474,421 (+)NCBI
RefSeq Acc Id: XM_063277179   ⟹   XP_063133249
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,438,185 - 27,474,421 (+)NCBI
RefSeq Acc Id: XM_063277180   ⟹   XP_063133250
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,428,191 - 27,474,421 (+)NCBI
RefSeq Acc Id: XM_063277181   ⟹   XP_063133251
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,437,886 - 27,474,421 (+)NCBI
RefSeq Acc Id: XM_063277182   ⟹   XP_063133252
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,437,868 - 27,467,258 (+)NCBI
RefSeq Acc Id: XM_063277183   ⟹   XP_063133253
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,438,183 - 27,467,258 (+)NCBI
RefSeq Acc Id: XM_063277184   ⟹   XP_063133254
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,438,183 - 27,467,258 (+)NCBI
RefSeq Acc Id: XM_063277185   ⟹   XP_063133255
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,437,758 - 27,467,258 (+)NCBI
RefSeq Acc Id: XM_063277186   ⟹   XP_063133256
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,437,784 - 27,467,258 (+)NCBI
RefSeq Acc Id: XM_063277187   ⟹   XP_063133257
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,437,734 - 27,474,421 (+)NCBI
RefSeq Acc Id: NP_062022   ⟸   NM_019149
- UniProtKB: Q5DVW1 (UniProtKB/Swiss-Prot),   O35833 (UniProtKB/Swiss-Prot),   P43244 (UniProtKB/Swiss-Prot),   A0A0G2JSR7 (UniProtKB/TrEMBL),   A6J2X6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254596   ⟸   XM_006254534
- Peptide Label: isoform X2
- UniProtKB: Q5DVW1 (UniProtKB/Swiss-Prot),   O35833 (UniProtKB/Swiss-Prot),   P43244 (UniProtKB/Swiss-Prot),   A0A0G2JSR7 (UniProtKB/TrEMBL),   A6J2X6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456375   ⟸   XM_017600886
- Peptide Label: isoform X2
- UniProtKB: Q5DVW1 (UniProtKB/Swiss-Prot),   O35833 (UniProtKB/Swiss-Prot),   P43244 (UniProtKB/Swiss-Prot),   A0A0G2JSR7 (UniProtKB/TrEMBL),   A6J2X6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456376   ⟸   XM_017600887
- Peptide Label: isoform X2
- UniProtKB: Q5DVW1 (UniProtKB/Swiss-Prot),   O35833 (UniProtKB/Swiss-Prot),   P43244 (UniProtKB/Swiss-Prot),   A0A0G2JSR7 (UniProtKB/TrEMBL),   A6J2X6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000026949   ⟸   ENSRNOT00000026949
Ensembl Acc Id: ENSRNOP00000073436   ⟸   ENSRNOT00000083993
RefSeq Acc Id: XP_063133250   ⟸   XM_063277180
- Peptide Label: isoform X1
- UniProtKB: Q5DVW1 (UniProtKB/Swiss-Prot),   P43244 (UniProtKB/Swiss-Prot),   O35833 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063133245   ⟸   XM_063277175
- Peptide Label: isoform X1
- UniProtKB: O35833 (UniProtKB/Swiss-Prot),   Q5DVW1 (UniProtKB/Swiss-Prot),   P43244 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063133257   ⟸   XM_063277187
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZWP0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133255   ⟸   XM_063277185
- Peptide Label: isoform X3
- UniProtKB: A6J2Y0 (UniProtKB/TrEMBL),   A0A8I5ZWP0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133256   ⟸   XM_063277186
- Peptide Label: isoform X3
- UniProtKB: A6J2Y0 (UniProtKB/TrEMBL),   A0A8I5ZWP0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133246   ⟸   XM_063277176
- Peptide Label: isoform X1
- UniProtKB: Q5DVW1 (UniProtKB/Swiss-Prot),   P43244 (UniProtKB/Swiss-Prot),   O35833 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063133252   ⟸   XM_063277182
- Peptide Label: isoform X2
- UniProtKB: Q5DVW1 (UniProtKB/Swiss-Prot),   P43244 (UniProtKB/Swiss-Prot),   O35833 (UniProtKB/Swiss-Prot),   A0A0G2JSR7 (UniProtKB/TrEMBL),   A6J2X6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133251   ⟸   XM_063277181
- Peptide Label: isoform X1
- UniProtKB: Q5DVW1 (UniProtKB/Swiss-Prot),   P43244 (UniProtKB/Swiss-Prot),   O35833 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063133248   ⟸   XM_063277178
- Peptide Label: isoform X1
- UniProtKB: Q5DVW1 (UniProtKB/Swiss-Prot),   P43244 (UniProtKB/Swiss-Prot),   O35833 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063133254   ⟸   XM_063277184
- Peptide Label: isoform X2
- UniProtKB: Q5DVW1 (UniProtKB/Swiss-Prot),   P43244 (UniProtKB/Swiss-Prot),   O35833 (UniProtKB/Swiss-Prot),   A0A0G2JSR7 (UniProtKB/TrEMBL),   A6J2X6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133253   ⟸   XM_063277183
- Peptide Label: isoform X2
- UniProtKB: Q5DVW1 (UniProtKB/Swiss-Prot),   P43244 (UniProtKB/Swiss-Prot),   O35833 (UniProtKB/Swiss-Prot),   A0A0G2JSR7 (UniProtKB/TrEMBL),   A6J2X6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133247   ⟸   XM_063277177
- Peptide Label: isoform X1
- UniProtKB: Q5DVW1 (UniProtKB/Swiss-Prot),   P43244 (UniProtKB/Swiss-Prot),   O35833 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063133249   ⟸   XM_063277179
- Peptide Label: isoform X1
- UniProtKB: Q5DVW1 (UniProtKB/Swiss-Prot),   P43244 (UniProtKB/Swiss-Prot),   O35833 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSRNOP00000103016   ⟸   ENSRNOT00000146659
Ensembl Acc Id: ENSRNOP00000100340   ⟸   ENSRNOT00000141241
Ensembl Acc Id: ENSRNOP00000110855   ⟸   ENSRNOT00000147139
Protein Domains
Matrin-type   RRM   U1-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P43244-F1-model_v2 AlphaFold P43244 1-845 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700708
Promoter ID:EPDNEW_R11231
Type:initiation region
Name:Matr3_1
Description:matrin 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01828,361,286 - 28,361,346EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3052 AgrOrtholog
BioCyc Gene G2FUF-7909 BioCyc
Ensembl Genes ENSRNOG00000019875 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000026949 ENTREZGENE
  ENSRNOT00000147139 ENTREZGENE
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6921221 IMAGE-MGC_LOAD
InterPro MATR3_RRM1 UniProtKB/Swiss-Prot
  MATR3_RRM2 UniProtKB/Swiss-Prot
  Matrin/U1-C_Znf_C2H2 UniProtKB/Swiss-Prot
  Matrin/U1-like-C_Znf_C2H2 UniProtKB/Swiss-Prot
  Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot
  RBD_domain_sf UniProtKB/Swiss-Prot
  RRM_dom UniProtKB/Swiss-Prot
KEGG Report rno:29150 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72856 IMAGE-MGC_LOAD
NCBI Gene 29150 ENTREZGENE
PANTHER MATRIN 3/NUCLEAR PROTEIN 220-RELATED UniProtKB/Swiss-Prot
PhenoGen Matr3 PhenoGen
PROSITE RRM UniProtKB/Swiss-Prot
  ZF_MATRIN UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000019875 RatGTEx
SMART RRM UniProtKB/Swiss-Prot
  ZnF_U1 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot
TIGR TC217434
UniProt A0A0G2JSR7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZWP0 ENTREZGENE
  A0ABK0LAS9_RAT UniProtKB/TrEMBL
  A0ABK0LRD8_RAT UniProtKB/TrEMBL
  A0ABK0M5H9_RAT UniProtKB/TrEMBL
  A6J2X6 ENTREZGENE, UniProtKB/TrEMBL
  A6J2Y0 ENTREZGENE, UniProtKB/TrEMBL
  B5DEM0_RAT UniProtKB/TrEMBL
  MATR3_RAT UniProtKB/Swiss-Prot
  O35833 ENTREZGENE
  P43244 ENTREZGENE
  Q5DVW1 ENTREZGENE
  Q6P6H1_RAT UniProtKB/TrEMBL
UniProt Secondary O35833 UniProtKB/Swiss-Prot
  Q5DVW1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Matr3  matrin 3      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_domains contains a highly acidic domain and a putative nuclear targeting signal sequence 69882