Mafb (MAF bZIP transcription factor B) - Rat Genome Database

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Gene: Mafb (MAF bZIP transcription factor B) Rattus norvegicus
Analyze
Symbol: Mafb
Name: MAF bZIP transcription factor B
RGD ID: 2982
Description: Enables DNA-binding transcription factor activity, RNA polymerase II-specific; identical protein binding activity; and sequence-specific double-stranded DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Duane retraction syndrome 3 and multicentric carpotarsal osteolysis syndrome. Orthologous to human MAFB (MAF bZIP transcription factor B); INTERACTS WITH (+)-schisandrin B; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1,2,4-trimethylbenzene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: b-maf; Kreisler (mouse) maf-related leucine zipper homolog (b-maf); Kreisler maf-related leucine zipper homolog (b-maf); Krml; maf-B; transcription factor Maf-1; transcription factor MafB; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian); v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83169,417,890 - 169,419,810 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3169,416,945 - 169,419,975 (-)EnsemblGRCr8
mRatBN7.23148,998,111 - 149,000,031 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3148,998,122 - 149,000,031 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3152,813,737 - 152,815,657 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03161,313,129 - 161,315,049 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03159,051,829 - 159,053,749 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03156,338,993 - 156,340,913 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3156,339,004 - 156,340,913 (-)Ensemblrn6Rnor6.0
Rnor_5.03162,572,668 - 162,574,588 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43151,116,831 - 151,118,751 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3147,675,895 - 147,677,815 (-)NCBICelera
RGSC_v3.13151,022,739 - 151,024,660 (-)NCBI
RH 3.4 Map31369.7RGD
Cytogenetic Map3q42NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2,4-trimethylbenzene  (EXP)
1,2-dichloroethane  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-amino-2-deoxy-D-glucopyranose  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
5-azacytidine  (ISO)
7,12-dimethyltetraphene  (EXP)
acrylamide  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (EXP)
all-trans-retinoic acid  (EXP,ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
asbestos  (ISO)
avobenzone  (ISO)
benzene-1,2,4-triol  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-D-glucosamine  (EXP)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
buta-1,3-diene  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
celastrol  (ISO)
choline  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
cyproconazole  (EXP)
DDE  (ISO)
dibenz[a,h]anthracene  (ISO)
Dibutyl phosphate  (ISO)
dichloromethane  (ISO)
diethylstilbestrol  (ISO)
dinophysistoxin 1  (ISO)
dioxygen  (ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
esketamine  (ISO)
fenitrothion  (ISO)
ferric oxide  (ISO)
flavonoids  (EXP)
flusilazole  (EXP,ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
gedunin  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
hexadecanoic acid  (ISO)
inulin  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
Licochalcone B  (ISO)
lipopolysaccharide  (ISO)
mercury dibromide  (ISO)
methotrexate  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
N-nitrosodiethylamine  (EXP)
naphthalenes  (EXP)
nefazodone  (EXP)
nickel atom  (ISO)
Nutlin-3  (ISO)
okadaic acid  (ISO)
orphenadrine  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (EXP,ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
propanal  (ISO)
SB 431542  (ISO)
sevoflurane  (EXP)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
Soman  (EXP)
succimer  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP,ISO)
Theaflavin 3,3'-digallate  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
triadimefon  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (EXP,ISO)
Triptolide  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
versicolorin A  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
4. Rat maf-related factors: the specificities of DNA binding and heterodimer formation. Matsushima-Hibiya Y, etal., Biochem Biophys Res Commun 1998 Apr 17;245(2):412-8.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Rat maf related genes: specific expression in chondrocytes, lens and spinal cord. Sakai M, etal., Oncogene 1997 Feb 13;14(6):745-50.
12. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:7925021   PMID:8620536   PMID:10698492   PMID:11823429   PMID:12701106   PMID:12798298   PMID:12917329   PMID:14513037   PMID:14581141   PMID:16325169   PMID:17928203   PMID:19164599  
PMID:19440205   PMID:22961837   PMID:26108485   PMID:27181683  


Genomics

Comparative Map Data
Mafb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83169,417,890 - 169,419,810 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3169,416,945 - 169,419,975 (-)EnsemblGRCr8
mRatBN7.23148,998,111 - 149,000,031 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3148,998,122 - 149,000,031 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3152,813,737 - 152,815,657 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03161,313,129 - 161,315,049 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03159,051,829 - 159,053,749 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03156,338,993 - 156,340,913 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3156,339,004 - 156,340,913 (-)Ensemblrn6Rnor6.0
Rnor_5.03162,572,668 - 162,574,588 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43151,116,831 - 151,118,751 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3147,675,895 - 147,677,815 (-)NCBICelera
RGSC_v3.13151,022,739 - 151,024,660 (-)NCBI
RH 3.4 Map31369.7RGD
Cytogenetic Map3q42NCBI
MAFB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382040,685,848 - 40,689,236 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2040,685,848 - 40,689,236 (-)Ensemblhg38GRCh38
GRCh372039,314,488 - 39,317,876 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362038,747,929 - 38,751,290 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342038,747,928 - 38,751,290NCBI
Celera2036,024,991 - 36,028,352 (-)NCBICelera
Cytogenetic Map20q12NCBI
HuRef2036,052,429 - 36,055,822 (-)NCBIHuRef
CHM1_12039,218,912 - 39,222,304 (-)NCBICHM1_1
T2T-CHM13v2.02042,417,334 - 42,420,722 (-)NCBIT2T-CHM13v2.0
Mafb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392160,205,597 - 160,208,985 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2160,205,623 - 160,208,985 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm382160,363,677 - 160,367,065 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2160,363,703 - 160,367,065 (-)Ensemblmm10GRCm38
MGSCv372160,189,413 - 160,192,801 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362160,055,202 - 160,058,455 (-)NCBIMGSCv36mm8
Celera2166,294,850 - 166,298,242 (-)NCBICelera
Cytogenetic Map2H2NCBI
cM Map280.92NCBI
Mafb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495544516,219,675 - 16,222,913 (+)NCBIChiLan1.0ChiLan1.0
MAFB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22146,425,575 - 46,429,119 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12046,418,674 - 46,422,133 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02037,023,988 - 37,027,446 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12038,125,705 - 38,128,724 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2038,127,722 - 38,128,693 (-)EnsemblpanPan2panpan1.1
MAFB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12428,769,904 - 28,772,519 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2428,770,944 - 28,774,948 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2428,416,065 - 28,419,157 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02429,474,707 - 29,477,799 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.12428,744,730 - 28,747,822 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02428,848,428 - 28,851,520 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02429,343,869 - 29,346,962 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mafb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640177,738,940 - 177,742,271 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365611,007,647 - 1,008,618 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365611,007,273 - 1,010,548 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAFB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1743,404,925 - 43,411,739 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11743,408,390 - 43,411,782 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21748,698,403 - 48,701,189 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MAFB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1223,092,547 - 23,097,721 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl223,094,713 - 23,095,684 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605071,901,067 - 71,904,494 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mafb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249191,339,228 - 1,340,208 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046249191,337,269 - 1,340,607 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Mafb
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15139,652,425 - 139,655,783 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:90
Count of miRNA genes:65
Interacting mature miRNAs:68
Transcripts:ENSRNOT00000021452
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141555229186555229Rat
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3141555229186555229Rat
1582233Insul10Insulin level QTL 105.40.0015blood insulin amount (VT:0001560)serum insulin level times blood glucose level (CMO:0002040)3133259579178259579Rat
1300113Bp176Blood pressure QTL 1763.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3166376089177728348Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3141555229186555229Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3151075912189428310Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3141555229186555229Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)3129154923182114333Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3141555229186555229Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3161492708189428310Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3141555229186555229Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3166376089189428310Rat
61335Bp20Blood pressure QTL 203arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3161799493176036425Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3161799270187311134Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3133134628178134628Rat
1582213Insul6Insulin level QTL 63.70.0009blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)3166376089189428310Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3152055202189428310Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3142898802187898802Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)3145335553189428310Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3125116475170116475Rat
1582256Insul9Insulin level QTL 94.40.0016blood insulin amount (VT:0001560)absolute change in serum insulin level (CMO:0002038)3155759447189428310Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3139299381184299381Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3141508991177728348Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3137114333182114333Rat
1582248Insul7Insulin level QTL 73.90.0041blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)3131036586176036586Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)3131036586176036586Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3151075912189428310Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3151075912189428310Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3141555229186555229Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3144575244189428310Rat

Markers in Region
RH94703  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23148,998,482 - 148,998,625 (+)MAPPERmRatBN7.2
Rnor_6.03156,339,365 - 156,339,507NCBIRnor6.0
Rnor_5.03162,573,040 - 162,573,182UniSTSRnor5.0
RGSC_v3.43151,117,203 - 151,117,345UniSTSRGSC3.4
Celera3147,676,267 - 147,676,409UniSTS
RH 3.4 Map31369.7UniSTS
Cytogenetic Map3q42UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 90 59 6 354 190 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000021452   ⟹   ENSRNOP00000021452
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3169,416,945 - 169,419,975 (-)Ensembl
mRatBN7.2 Ensembl3148,998,122 - 149,000,031 (-)Ensembl
Rnor_6.0 Ensembl3156,339,004 - 156,340,913 (-)Ensembl
RefSeq Acc Id: NM_019316   ⟹   NP_062189
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83169,417,890 - 169,419,810 (-)NCBI
mRatBN7.23148,998,111 - 149,000,031 (-)NCBI
Rnor_6.03156,338,993 - 156,340,913 (-)NCBI
Rnor_5.03162,572,668 - 162,574,588 (-)NCBI
RGSC_v3.43151,116,831 - 151,118,751 (-)RGD
Celera3147,675,895 - 147,677,815 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_062189 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB50062 (Get FASTA)   NCBI Sequence Viewer  
  EDL96623 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000021452.1
GenBank Protein P54842 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_062189   ⟸   NM_019316
- UniProtKB: P54842 (UniProtKB/Swiss-Prot),   A6JWY6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021452   ⟸   ENSRNOT00000021452
Protein Domains
bZIP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P54842-F1-model_v2 AlphaFold P54842 1-323 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2982 AgrOrtholog
BioCyc Gene G2FUF-46987 BioCyc
Ensembl Genes ENSRNOG00000016037 Ensembl, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000021452.4 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.170 UniProtKB/Swiss-Prot
InterPro bZIP UniProtKB/Swiss-Prot
  bZIP_Maf UniProtKB/Swiss-Prot
  bZIP_sf UniProtKB/Swiss-Prot
  Maf_TF_N UniProtKB/Swiss-Prot
  TF_DNA-bd_sf UniProtKB/Swiss-Prot
  Transciption_factor_Maf_fam UniProtKB/Swiss-Prot
KEGG Report rno:54264 UniProtKB/Swiss-Prot
NCBI Gene 54264 ENTREZGENE
PANTHER PTHR10129 UniProtKB/Swiss-Prot
  PTHR10129:SF10 UniProtKB/Swiss-Prot
Pfam bZIP_Maf UniProtKB/Swiss-Prot
  Maf_N UniProtKB/Swiss-Prot
PhenoGen Mafb PhenoGen
PROSITE BZIP UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000016037 RatGTEx
SMART BRLZ UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47454 UniProtKB/Swiss-Prot
  SSF57959 UniProtKB/Swiss-Prot
TIGR TC220758
UniProt A6JWY6 ENTREZGENE, UniProtKB/TrEMBL
  MAFB_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-18 Mafb  MAF bZIP transcription factor B  Mafb  v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-07-18 Mafb  v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B  Mafb  v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-30 Mafb  v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)  Mafb  v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2001-12-17 Mafb  v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)      Symbol and Name updated to reflect Human and Mouse nomenclature 69665 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in spleen, kidney, muscle and liver 69874