MAFB (MAF bZIP transcription factor B) - Rat Genome Database

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Gene: MAFB (MAF bZIP transcription factor B) Chlorocebus sabaeus
Analyze
Symbol: MAFB
Name: MAF bZIP transcription factor B
RGD ID: 18589674
Description: ENCODES a protein that exhibits DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); identical protein binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN brain segmentation (ortholog); inner ear morphogenesis (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH cleft lip (ortholog); COVID-19 (ortholog); Duane retraction syndrome (ortholog); FOUND IN nucleus (ortholog); RNA polymerase II transcription regulator complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transcription factor MafB
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1223,092,547 - 23,097,721 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl223,094,713 - 23,095,684 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605071,901,067 - 71,904,494 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
MAFB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1223,092,547 - 23,097,721 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl223,094,713 - 23,095,684 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605071,901,067 - 71,904,494 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
MAFB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382040,685,848 - 40,689,236 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2040,685,848 - 40,689,236 (-)EnsemblGRCh38hg38GRCh38
GRCh372039,314,488 - 39,317,876 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362038,747,929 - 38,751,290 (-)NCBINCBI36Build 36hg18NCBI36
Build 342038,747,928 - 38,751,290NCBI
Celera2036,024,991 - 36,028,352 (-)NCBICelera
Cytogenetic Map20q12NCBI
HuRef2036,052,429 - 36,055,822 (-)NCBIHuRef
CHM1_12039,218,912 - 39,222,304 (-)NCBICHM1_1
T2T-CHM13v2.02042,417,334 - 42,420,722 (-)NCBIT2T-CHM13v2.0
Mafb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392160,205,597 - 160,208,985 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2160,205,623 - 160,208,985 (-)EnsemblGRCm39 Ensembl
GRCm382160,363,677 - 160,367,065 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2160,363,703 - 160,367,065 (-)EnsemblGRCm38mm10GRCm38
MGSCv372160,189,413 - 160,192,801 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362160,055,202 - 160,058,455 (-)NCBIMGSCv36mm8
Celera2166,294,850 - 166,298,242 (-)NCBICelera
Cytogenetic Map2H2NCBI
cM Map280.92NCBI
Mafb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83169,417,890 - 169,419,810 (-)NCBIGRCr8
mRatBN7.23148,998,111 - 149,000,031 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3148,998,122 - 149,000,031 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3152,813,737 - 152,815,657 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03161,313,129 - 161,315,049 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03159,051,829 - 159,053,749 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03156,338,993 - 156,340,913 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3156,339,004 - 156,340,913 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03162,572,668 - 162,574,588 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43151,116,831 - 151,118,751 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13151,022,739 - 151,024,660 (-)NCBI
Celera3147,675,895 - 147,677,815 (-)NCBICelera
RH 3.4 Map31369.7RGD
Cytogenetic Map3q42NCBI
Mafb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495544516,219,675 - 16,222,913 (+)NCBIChiLan1.0ChiLan1.0
MAFB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22146,425,575 - 46,429,119 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12046,418,674 - 46,422,133 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02037,023,988 - 37,027,446 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12038,125,705 - 38,128,724 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2038,127,722 - 38,128,693 (-)Ensemblpanpan1.1panPan2
MAFB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12428,769,904 - 28,772,519 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2428,770,944 - 28,774,948 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2428,416,065 - 28,419,157 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02429,474,707 - 29,477,799 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12428,744,730 - 28,747,822 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02428,848,428 - 28,851,520 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02429,343,869 - 29,346,962 (-)NCBIUU_Cfam_GSD_1.0
Mafb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640177,738,940 - 177,742,271 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365611,007,647 - 1,008,618 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365611,007,273 - 1,010,548 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAFB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1743,404,927 - 43,411,739 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11743,408,390 - 43,411,782 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21748,698,403 - 48,701,189 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Mafb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249191,339,228 - 1,340,208 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249191,337,269 - 1,340,607 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 12
Low 24 20 60
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008017360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000018843   ⟹   ENSCSAP00000018275
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl223,094,713 - 23,095,684 (+)Ensembl
RefSeq Acc Id: XM_008017360   ⟹   XP_008015551
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1223,092,547 - 23,097,721 (+)NCBI
Vero_WHO_p1.0NW_02366605071,901,067 - 71,904,494 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008015551 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000018275
  ENSCSAP00000018275.1
Reference Protein Sequences
RefSeq Acc Id: XP_008015551   ⟸   XM_008017360
- UniProtKB: A0A0D9SBN6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000018275   ⟸   ENSCSAT00000018843


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000018753 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000018843.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
InterPro bZIP UniProtKB/TrEMBL
  bZIP_Maf UniProtKB/TrEMBL
  bZIP_sf UniProtKB/TrEMBL
  Maf_TF_N UniProtKB/TrEMBL
  TF_DNA-bd_sf UniProtKB/TrEMBL
  Transcription_factor_Maf_fam UniProtKB/TrEMBL
KEGG Report csab:103246024 UniProtKB/TrEMBL
NCBI Gene MAFB ENTREZGENE
PANTHER PTHR10129 UniProtKB/TrEMBL
  PTHR10129:SF10 UniProtKB/TrEMBL
Pfam bZIP_Maf UniProtKB/TrEMBL
  Maf_N UniProtKB/TrEMBL
PROSITE BZIP UniProtKB/TrEMBL
SMART BRLZ UniProtKB/TrEMBL
Superfamily-SCOP SSF47454 UniProtKB/TrEMBL
  SSF57959 UniProtKB/TrEMBL
UniProt A0A0D9SBN6 ENTREZGENE, UniProtKB/TrEMBL