Kap (kidney androgen regulated protein) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Kap (kidney androgen regulated protein) Rattus norvegicus
Analyze
Symbol: Kap
Name: kidney androgen regulated protein
RGD ID: 2947
Description: Predicted to be located in extracellular region. Orthologous to human TVP23C-CDRT4 (TVP23C-CDRT4 readthrough); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ARP; Kidney androgen-regulated protein
RGD Orthologs
Human
Mouse
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84168,405,981 - 168,409,032 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4168,405,988 - 168,409,032 (-)EnsemblGRCr8
mRatBN7.24166,674,595 - 166,677,639 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4166,674,595 - 166,677,639 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4172,968,010 - 172,971,054 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04168,751,059 - 168,754,103 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04167,377,016 - 167,380,060 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04167,549,922 - 167,552,973 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4167,549,929 - 167,552,973 (-)Ensemblrn6Rnor6.0
Rnor_5.04230,077,253 - 230,080,304 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44170,652,195 - 170,655,239 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4155,280,749 - 155,283,793 (-)NCBICelera
RGSC_v3.14170,897,130 - 170,900,175 (-)NCBI
Cytogenetic Map4q42NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
2. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Kap
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84168,405,981 - 168,409,032 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4168,405,988 - 168,409,032 (-)EnsemblGRCr8
mRatBN7.24166,674,595 - 166,677,639 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4166,674,595 - 166,677,639 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4172,968,010 - 172,971,054 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04168,751,059 - 168,754,103 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04167,377,016 - 167,380,060 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04167,549,922 - 167,552,973 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4167,549,929 - 167,552,973 (-)Ensemblrn6Rnor6.0
Rnor_5.04230,077,253 - 230,080,304 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44170,652,195 - 170,655,239 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4155,280,749 - 155,283,793 (-)NCBICelera
RGSC_v3.14170,897,130 - 170,900,175 (-)NCBI
Cytogenetic Map4q42NCBI
TVP23C-CDRT4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381715,436,015 - 15,563,483 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1715,436,021 - 15,563,561 (-)Ensemblhg38GRCh38
GRCh371715,339,332 - 15,466,797 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map17p12NCBI
HuRef1715,232,750 - 15,237,021 (-)NCBIHuRef
CHM1_11715,348,150 - 15,475,876 (-)NCBICHM1_1
T2T-CHM13v2.01715,342,066 - 15,469,716 (-)NCBIT2T-CHM13v2.0
Kap
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396133,826,818 - 133,830,630 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6133,826,814 - 133,830,725 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm386133,849,855 - 133,853,667 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6133,849,851 - 133,853,762 (-)Ensemblmm10GRCm38
MGSCv376133,799,873 - 133,803,685 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv366133,815,548 - 133,819,363 (-)NCBIMGSCv36mm8
Celera6136,799,740 - 136,803,560 (-)NCBICelera
Cytogenetic Map6G1NCBI
cM Map664.03NCBI

Variants

.
Variants in Kap
22 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:164
Count of miRNA genes:130
Interacting mature miRNAs:144
Transcripts:ENSRNOT00000007806
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4146370897184426481Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4134095016179095016Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4149763204169799698Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4146370897184426481Rat
6478757Anxrr44Anxiety related response QTL 440.01087locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
1358364Sradr4Stress Responsive Adrenal Weight QTL 44.92adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)4131384565176384565Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4123870974168870974Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4140059299181024663Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4157292416184426481Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)494638356168870820Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4106848959168870974Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4127263297172263297Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4126334185171334185Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4147299608184426481Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
6478782Anxrr52Anxiety related response QTL 520.02091locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4124700988169700988Rat
6478720Alc23Alcohol consumption QTL 230.00509drinking behavior trait (VT:0001422)ethanol drink intake rate to body weight ratio (CMO:0001616)4155834926184426481Rat
6478785Anxrr53Anxiety related response QTL 530.01397locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)4100752691179366077Rat
1581566Eae21Experimental allergic encephalomyelitis QTL 216.2body mass (VT:0001259)maximum body weight loss to initial body weight ratio (CMO:0001400)4137447185182447185Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4137430611182430611Rat
6478728Anxrr36Anxiety related response QTL 360.01061locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)486709649168870974Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4134199006168870974Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4148121375176967367Rat
6478733Anxrr37Anxiety related response QTL 370.00095locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
6478737Anxrr38Anxiety related response QTL 380.00159locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4160623982184426481Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
12798525Anxrr57Anxiety related response QTL 573.210.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4148834094168870974Rat

Markers in Region
RH134581  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24166,674,649 - 166,674,841 (+)MAPPERmRatBN7.2
Rnor_6.04167,549,984 - 167,550,175NCBIRnor6.0
Rnor_5.04230,077,315 - 230,077,506UniSTSRnor5.0
RGSC_v3.44170,652,250 - 170,652,441UniSTSRGSC3.4
Celera4155,280,804 - 155,280,995UniSTS
RH 3.4 Map41015.7UniSTS
Cytogenetic Map4q43UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
8 8 21 37 39 42 20 25 20 2 169 54 27 79 66 22

Sequence


Ensembl Acc Id: ENSRNOT00000007806   ⟹   ENSRNOP00000007806
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4168,405,988 - 168,409,032 (-)Ensembl
mRatBN7.2 Ensembl4166,674,595 - 166,677,639 (-)Ensembl
Rnor_6.0 Ensembl4167,549,929 - 167,552,973 (-)Ensembl
RefSeq Acc Id: NM_052802   ⟹   NP_434689
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84168,405,988 - 168,409,032 (-)NCBI
mRatBN7.24166,674,595 - 166,677,639 (-)NCBI
Rnor_6.04167,549,929 - 167,552,973 (-)NCBI
Rnor_5.04230,077,253 - 230,080,304 (-)NCBI
RGSC_v3.44170,652,195 - 170,655,239 (-)RGD
Celera4155,280,749 - 155,283,793 (-)RGD
Sequence:
RefSeq Acc Id: XM_063285571   ⟹   XP_063141641
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84168,405,981 - 168,409,024 (-)NCBI
Protein Sequences
Protein RefSeqs NP_434689 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141641 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA67078 (Get FASTA)   NCBI Sequence Viewer  
  EDM01663 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000007806
  ENSRNOP00000007806.1
GenBank Protein Q62781 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_434689   ⟸   NM_052802
- Peptide Label: precursor
- UniProtKB: Q62781 (UniProtKB/Swiss-Prot),   A6IMC6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000007806   ⟸   ENSRNOT00000007806
RefSeq Acc Id: XP_063141641   ⟸   XM_063285571
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62781-F1-model_v2 AlphaFold Q62781 1-120 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693447
Promoter ID:EPDNEW_R3971
Type:multiple initiation site
Name:Kap_1
Description:kidney androgen regulated protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04167,552,862 - 167,552,922EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2947 AgrOrtholog
BioCyc Gene G2FUF-42669 BioCyc
Ensembl Genes ENSRNOG00000005858 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000007806 ENTREZGENE
  ENSRNOT00000007806.3 UniProtKB/Swiss-Prot
InterPro KAR_prot UniProtKB/Swiss-Prot
KEGG Report rno:24937 UniProtKB/Swiss-Prot
NCBI Gene 24937 ENTREZGENE
Pfam KAR UniProtKB/Swiss-Prot
PhenoGen Kap PhenoGen
RatGTEx ENSRNOG00000005858 RatGTEx
UniProt A6IMC6 ENTREZGENE, UniProtKB/TrEMBL
  ANRE_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Kap  Kidney androgen-regulated protein      Symbol and Name status set to approved 70586 APPROVED